hypothetical protein YWA314_00159 [Yersinia enterocolitica subsp. enterocolitica WA-314]
Protein Classification
glycosyltransferase family protein( domain architecture ID 56)
glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| Glycosyltransferase_GTB-type super family | cl10013 | glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ... |
206-428 | 1.22e-11 | ||||
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The actual alignment was detected with superfamily member cd03801: Pssm-ID: 471961 [Multi-domain] Cd Length: 366 Bit Score: 66.02 E-value: 1.22e-11
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| ERG3 super family | cl27195 | Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid ... |
153-190 | 4.24e-04 | ||||
Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]; The actual alignment was detected with superfamily member COG3000: Pssm-ID: 442238 Cd Length: 158 Bit Score: 40.69 E-value: 4.24e-04
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| Name | Accession | Description | Interval | E-value | ||||
| GT4_PimA-like | cd03801 | phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
206-428 | 1.22e-11 | ||||
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 66.02 E-value: 1.22e-11
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| ERG3 | COG3000 | Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid ... |
153-190 | 4.24e-04 | ||||
Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]; Pssm-ID: 442238 Cd Length: 158 Bit Score: 40.69 E-value: 4.24e-04
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| Name | Accession | Description | Interval | E-value | ||||
| GT4_PimA-like | cd03801 | phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ... |
206-428 | 1.22e-11 | ||||
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. Pssm-ID: 340831 [Multi-domain] Cd Length: 366 Bit Score: 66.02 E-value: 1.22e-11
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| GT4_ALG11-like | cd03806 | alpha-1,2-mannosyltransferase ALG11 and similar proteins; This family is most closely related ... |
237-346 | 2.52e-04 | ||||
alpha-1,2-mannosyltransferase ALG11 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides. Pssm-ID: 340835 [Multi-domain] Cd Length: 419 Bit Score: 43.37 E-value: 2.52e-04
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| ERG3 | COG3000 | Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid ... |
153-190 | 4.24e-04 | ||||
Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]; Pssm-ID: 442238 Cd Length: 158 Bit Score: 40.69 E-value: 4.24e-04
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| GT4_MtfB-like | cd03809 | glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ... |
207-336 | 3.85e-03 | ||||
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide. Pssm-ID: 340838 [Multi-domain] Cd Length: 362 Bit Score: 39.27 E-value: 3.85e-03
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| Blast search parameters | ||||
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