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Conserved domains on  [gi|398218360|gb|EJN04870|]
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NADH dehydrogenase, FAD-containing subunit [Phyllobacterium sp. YR531]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11441299)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; similar to sulfide:quinone oxidoreductase which catalyzes the oxidation of hydrogen sulfide using quinone as the electron acceptor

EC:  1.6.-.-
Gene Ontology:  GO:0003954|GO:0006116
PubMed:  15590775|28181562

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
10-402 4.39e-167

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


:

Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 474.24  E-value: 4.39e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  10 RHRLVIVGAGFGGLVTVQNLRK---ADIDITLIDQRNHHLFQPLLYQVATSTLATSEIAWPIRHLLRKfKNVKTLLGTVD 86
Cdd:COG1252    1 MKRIVIVGGGFAGLEAARRLRKklgGDAEVTLIDPNPYHLFQPLLPEVAAGTLSPDDIAIPLRELLRR-AGVRFIQGEVT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  87 HVDTAKRTVSTVDGETIPYDTLVLATGARHAYFGHDDWEPFAPGLKTLEDATMIRRRILTAFEKAEREpdpakreELLTF 166
Cdd:COG1252   80 GIDPEARTVTLADGRTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAFERAERR-------RLLTI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 167 VIIGGGPTGVEIAGTLADLARDTLKgdFRVIDPAMAKVVLIEGGSRVLGAFNEELSAYAQRALEKLGVTVHVGNPVTACH 246
Cdd:COG1252  153 VVVGGGPTGVELAGELAELLRKLLR--YPGIDPDKVRITLVEAGPRILPGLGEKLSEAAEKELEKRGVEVHTGTRVTEVD 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 247 ADGVEFA-GHSLRAKTIIWAAGVQASPAAKWLNAPADRAGRLAVNPDLTAPDHPEIFVIGDTATVANGDKGNVPGIAPAA 325
Cdd:COG1252  231 ADGVTLEdGEEIPADTVIWAAGVKAPPLLADLGLPTDRRGRVLVDPTLQVPGHPNVFAIGDCAAVPDPDGKPVPKTAQAA 310

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 398218360 326 KQQGAHVAKTIKARLAGDnEPKPFRYRHAGDLATIGKRAAVTDFGFIKLKGYPAWWLWGLAHIYFLIGVRNRLAVAL 402
Cdd:COG1252  311 VQQAKVLAKNIAALLRGK-PLKPFRYRDKGCLASLGRGAAVADVGGLKLSGFLAWLLKRAIHLYFLPGFRGRLRVLL 386
 
Name Accession Description Interval E-value
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
10-402 4.39e-167

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 474.24  E-value: 4.39e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  10 RHRLVIVGAGFGGLVTVQNLRK---ADIDITLIDQRNHHLFQPLLYQVATSTLATSEIAWPIRHLLRKfKNVKTLLGTVD 86
Cdd:COG1252    1 MKRIVIVGGGFAGLEAARRLRKklgGDAEVTLIDPNPYHLFQPLLPEVAAGTLSPDDIAIPLRELLRR-AGVRFIQGEVT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  87 HVDTAKRTVSTVDGETIPYDTLVLATGARHAYFGHDDWEPFAPGLKTLEDATMIRRRILTAFEKAEREpdpakreELLTF 166
Cdd:COG1252   80 GIDPEARTVTLADGRTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAFERAERR-------RLLTI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 167 VIIGGGPTGVEIAGTLADLARDTLKgdFRVIDPAMAKVVLIEGGSRVLGAFNEELSAYAQRALEKLGVTVHVGNPVTACH 246
Cdd:COG1252  153 VVVGGGPTGVELAGELAELLRKLLR--YPGIDPDKVRITLVEAGPRILPGLGEKLSEAAEKELEKRGVEVHTGTRVTEVD 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 247 ADGVEFA-GHSLRAKTIIWAAGVQASPAAKWLNAPADRAGRLAVNPDLTAPDHPEIFVIGDTATVANGDKGNVPGIAPAA 325
Cdd:COG1252  231 ADGVTLEdGEEIPADTVIWAAGVKAPPLLADLGLPTDRRGRVLVDPTLQVPGHPNVFAIGDCAAVPDPDGKPVPKTAQAA 310

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 398218360 326 KQQGAHVAKTIKARLAGDnEPKPFRYRHAGDLATIGKRAAVTDFGFIKLKGYPAWWLWGLAHIYFLIGVRNRLAVAL 402
Cdd:COG1252  311 VQQAKVLAKNIAALLRGK-PLKPFRYRDKGCLASLGRGAAVADVGGLKLSGFLAWLLKRAIHLYFLPGFRGRLRVLL 386
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 10-405 2.78e-80

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 253.92  E-value: 2.78e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  10 RHRLVIVGAGFGGLVTVQNLRKADIDITLIDQRNHHLFQPLLYQVATSTLATSEIAWPIRHLLRKFKNvKTLLGTVDHVD 89
Cdd:PTZ00318  10 KPNVVVLGTGWAGAYFVRNLDPKKYNITVISPRNHMLFTPLLPQTTTGTLEFRSICEPVRPALAKLPN-RYLRAVVYDVD 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  90 TAKRTV----------STVDGETIPYDTLVLATGARHAYFGHDDWEPFAPGLKTLEDATMIRRRILTAFEKAER-EPDPA 158
Cdd:PTZ00318  89 FEEKRVkcgvvsksnnANVNTFSVPYDKLVVAHGARPNTFNIPGVEERAFFLKEVNHARGIRKRIVQCIERASLpTTSVE 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 159 KREELLTFVIIGGGPTGVEIAGTLADLARDtlkgDFRVIDPAM---AKVVLIEGGSRVLGAFNEELSAYAQRALEKLGVT 235
Cdd:PTZ00318 169 ERKRLLHFVVVGGGPTGVEFAAELADFFRD----DVRNLNPELveeCKVTVLEAGSEVLGSFDQALRKYGQRRLRRLGVD 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 236 VHVGNPVTACHADGVEF-AGHSLRAKTIIWAAGVQASPAAKWLNAPADRAGRLAVNPDLTAPDHPEIFVIGDTATVangD 314
Cdd:PTZ00318 245 IRTKTAVKEVLDKEVVLkDGEVIPTGLVVWSTGVGPGPLTKQLKVDKTSRGRISVDDHLRVKPIPNVFALGDCAAN---E 321

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 315 KGNVPGIAPAAKQQGAHVAKTIKARLAGDNEPKPFRYRHAGDLATIGKRAAVTDFGFIKLKGYPAWWLWGLAHIYFLIGV 394
Cdd:PTZ00318 322 ERPLPTLAQVASQQGVYLAKEFNNELKGKPMSKPFVYRSLGSLAYLGNYSAIVQLGAFDLSGFKALLFWRSAYLTILGSW 401

                        410
                 ....*....|.
gi 398218360 395 RNRLAVALSWL 405
Cdd:PTZ00318 402 RSKLYVLVNWA 412
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 11-329 2.97e-45

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 159.02  E-value: 2.97e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360   11 HRLVIVGAGFGGLVTVQNLRKADIDITLI-DQRNHHLFQPLLYQVATSTLATSEIAWPIRHLLRKFK--------NVKTL 81
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIeDEGTCPYGGCVLSKALLGAAEAPEIASLWADLYKRKEevvkklnnGIEVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360   82 LGT-VDHVDTAKRTV-----STVDGETIPYDTLVLATGARhayfghddwePFAPGLKTLEDATMIRRRILTAFEKAEREP 155
Cdd:pfam07992  81 LGTeVVSIDPGAKKVvleelVDGDGETITYDRLVIATGAR----------PRLPPIPGVELNVGFLVRTLDSAEALRLKL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  156 DPAKreelltFVIIGGGPTGVEIAGTLADLArdtlkgdfrvidpamAKVVLIEGGSRVLGAFNEELSAYAQRALEKLGVT 235
Cdd:pfam07992 151 LPKR------VVVVGGGYIGVELAAALAKLG---------------KEVTLIEALDRLLRAFDEEISAALEKALEKNGVE 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  236 VHVGNPVTACHADGVEFA-----GHSLRAKTIIWAAGVQASPA-AKWLNAPADRAGRLAVNPDLtAPDHPEIFVIGDTat 309
Cdd:pfam07992 210 VRLGTSVKEIIGDGDGVEvilkdGTEIDADLVVVAIGRRPNTElLEAAGLELDERGGIVVDEYL-RTSVPGIYAAGDC-- 286

                         330       340
                  ....*....|....*....|
gi 398218360  310 vangdKGNVPGIAPAAKQQG 329
Cdd:pfam07992 287 -----RVGGPELAQNAVAQG 301
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 13-371 1.16e-17

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 85.65  E-value: 1.16e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360   13 LVIVGAGFGGLVTVQNLRKAD---IDITLIDQRNHHLFQPLLYQVATSTLAT-SEIAWPIRHLLRKfKNVKTLLG-TVDH 87
Cdd:TIGR02374   1 LVLVGNGMAGHRCIEEVLKLNrhmFEITIFGEEPHPNYNRILLSSVLQGEADlDDITLNSKDWYEK-HGITLYTGeTVIQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360   88 VDTAKRTVSTVDGETIPYDTLVLATGArHAYF----GHDdwEPFAPGLKTLEDATMIRrriltafEKAEREPDPAkreel 163
Cdd:TIGR02374  80 IDTDQKQVITDAGRTLSYDKLILATGS-YPFIlpipGAD--KKGVYVFRTIEDLDAIM-------AMAQRFKKAA----- 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  164 ltfvIIGGGPTGVEIAGTLADLARDTlkgdfRVIDPA---MAKvVLIEGGSRVLgafneelsayaQRALEKLGVTVHVGN 240
Cdd:TIGR02374 145 ----VIGGGLLGLEAAVGLQNLGMDV-----SVIHHApglMAK-QLDQTAGRLL-----------QRELEQKGLTFLLEK 203

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  241 P----VTACHADGVEFA-GHSLRAKTIIWAAGVQasPAAKWLNAPADRAGRLAVNPDLTAPDHPEIFVIGDTATVangdK 315
Cdd:TIGR02374 204 DtveiVGATKADRIRFKdGSSLEADLIVMAAGIR--PNDELAVSAGIKVNRGIIVNDSMQTSDPDIYAVGECAEH----N 277

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 398218360  316 GNVPG-IAPAAKQqgahvAKTIKARLAGdNEPKPFRyrhAGDLATIGKRAAVTDFGF 371
Cdd:TIGR02374 278 GRVYGlVAPLYEQ-----AKVLADHICG-VECEEYE---GSDLSAKLKLLGVDVWSA 325
 
Name Accession Description Interval E-value
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
10-402 4.39e-167

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 474.24  E-value: 4.39e-167
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  10 RHRLVIVGAGFGGLVTVQNLRK---ADIDITLIDQRNHHLFQPLLYQVATSTLATSEIAWPIRHLLRKfKNVKTLLGTVD 86
Cdd:COG1252    1 MKRIVIVGGGFAGLEAARRLRKklgGDAEVTLIDPNPYHLFQPLLPEVAAGTLSPDDIAIPLRELLRR-AGVRFIQGEVT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  87 HVDTAKRTVSTVDGETIPYDTLVLATGARHAYFGHDDWEPFAPGLKTLEDATMIRRRILTAFEKAEREpdpakreELLTF 166
Cdd:COG1252   80 GIDPEARTVTLADGRTLSYDYLVIATGSVTNFFGIPGLAEHALPLKTLEDALALRERLLAAFERAERR-------RLLTI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 167 VIIGGGPTGVEIAGTLADLARDTLKgdFRVIDPAMAKVVLIEGGSRVLGAFNEELSAYAQRALEKLGVTVHVGNPVTACH 246
Cdd:COG1252  153 VVVGGGPTGVELAGELAELLRKLLR--YPGIDPDKVRITLVEAGPRILPGLGEKLSEAAEKELEKRGVEVHTGTRVTEVD 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 247 ADGVEFA-GHSLRAKTIIWAAGVQASPAAKWLNAPADRAGRLAVNPDLTAPDHPEIFVIGDTATVANGDKGNVPGIAPAA 325
Cdd:COG1252  231 ADGVTLEdGEEIPADTVIWAAGVKAPPLLADLGLPTDRRGRVLVDPTLQVPGHPNVFAIGDCAAVPDPDGKPVPKTAQAA 310

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 398218360 326 KQQGAHVAKTIKARLAGDnEPKPFRYRHAGDLATIGKRAAVTDFGFIKLKGYPAWWLWGLAHIYFLIGVRNRLAVAL 402
Cdd:COG1252  311 VQQAKVLAKNIAALLRGK-PLKPFRYRDKGCLASLGRGAAVADVGGLKLSGFLAWLLKRAIHLYFLPGFRGRLRVLL 386
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 10-405 2.78e-80

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 253.92  E-value: 2.78e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  10 RHRLVIVGAGFGGLVTVQNLRKADIDITLIDQRNHHLFQPLLYQVATSTLATSEIAWPIRHLLRKFKNvKTLLGTVDHVD 89
Cdd:PTZ00318  10 KPNVVVLGTGWAGAYFVRNLDPKKYNITVISPRNHMLFTPLLPQTTTGTLEFRSICEPVRPALAKLPN-RYLRAVVYDVD 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  90 TAKRTV----------STVDGETIPYDTLVLATGARHAYFGHDDWEPFAPGLKTLEDATMIRRRILTAFEKAER-EPDPA 158
Cdd:PTZ00318  89 FEEKRVkcgvvsksnnANVNTFSVPYDKLVVAHGARPNTFNIPGVEERAFFLKEVNHARGIRKRIVQCIERASLpTTSVE 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 159 KREELLTFVIIGGGPTGVEIAGTLADLARDtlkgDFRVIDPAM---AKVVLIEGGSRVLGAFNEELSAYAQRALEKLGVT 235
Cdd:PTZ00318 169 ERKRLLHFVVVGGGPTGVEFAAELADFFRD----DVRNLNPELveeCKVTVLEAGSEVLGSFDQALRKYGQRRLRRLGVD 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 236 VHVGNPVTACHADGVEF-AGHSLRAKTIIWAAGVQASPAAKWLNAPADRAGRLAVNPDLTAPDHPEIFVIGDTATVangD 314
Cdd:PTZ00318 245 IRTKTAVKEVLDKEVVLkDGEVIPTGLVVWSTGVGPGPLTKQLKVDKTSRGRISVDDHLRVKPIPNVFALGDCAAN---E 321

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 315 KGNVPGIAPAAKQQGAHVAKTIKARLAGDNEPKPFRYRHAGDLATIGKRAAVTDFGFIKLKGYPAWWLWGLAHIYFLIGV 394
Cdd:PTZ00318 322 ERPLPTLAQVASQQGVYLAKEFNNELKGKPMSKPFVYRSLGSLAYLGNYSAIVQLGAFDLSGFKALLFWRSAYLTILGSW 401

                        410
                 ....*....|.
gi 398218360 395 RNRLAVALSWL 405
Cdd:PTZ00318 402 RSKLYVLVNWA 412
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 11-329 2.97e-45

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 159.02  E-value: 2.97e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360   11 HRLVIVGAGFGGLVTVQNLRKADIDITLI-DQRNHHLFQPLLYQVATSTLATSEIAWPIRHLLRKFK--------NVKTL 81
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIeDEGTCPYGGCVLSKALLGAAEAPEIASLWADLYKRKEevvkklnnGIEVL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360   82 LGT-VDHVDTAKRTV-----STVDGETIPYDTLVLATGARhayfghddwePFAPGLKTLEDATMIRRRILTAFEKAEREP 155
Cdd:pfam07992  81 LGTeVVSIDPGAKKVvleelVDGDGETITYDRLVIATGAR----------PRLPPIPGVELNVGFLVRTLDSAEALRLKL 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  156 DPAKreelltFVIIGGGPTGVEIAGTLADLArdtlkgdfrvidpamAKVVLIEGGSRVLGAFNEELSAYAQRALEKLGVT 235
Cdd:pfam07992 151 LPKR------VVVVGGGYIGVELAAALAKLG---------------KEVTLIEALDRLLRAFDEEISAALEKALEKNGVE 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  236 VHVGNPVTACHADGVEFA-----GHSLRAKTIIWAAGVQASPA-AKWLNAPADRAGRLAVNPDLtAPDHPEIFVIGDTat 309
Cdd:pfam07992 210 VRLGTSVKEIIGDGDGVEvilkdGTEIDADLVVVAIGRRPNTElLEAAGLELDERGGIVVDEYL-RTSVPGIYAAGDC-- 286

                         330       340
                  ....*....|....*....|
gi 398218360  310 vangdKGNVPGIAPAAKQQG 329
Cdd:pfam07992 287 -----RVGGPELAQNAVAQG 301
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
10-346 2.72e-38

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 142.97  E-value: 2.72e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  10 RHRLVIVGAGFGGLVTVQNLRKAD--IDITLIDQRNHHLFQ--PLLYQVATST----LATSEIAWPIRHllrkfkNVKTL 81
Cdd:COG1251    1 KMRIVIIGAGMAGVRAAEELRKLDpdGEITVIGAEPHPPYNrpPLSKVLAGETdeedLLLRPADFYEEN------GIDLR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  82 LGT-VDHVDTAKRTVSTVDGETIPYDTLVLATGARhayfghddwePFAP-----------GLKTLEDAtmirRRILTAFE 149
Cdd:COG1251   75 LGTrVTAIDRAARTVTLADGETLPYDKLVLATGSR----------PRVPpipgadlpgvfTLRTLDDA----DALRAALA 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 150 KAERepdpakreelltFVIIGGGPTGVEIAGTLADLardtlkGdfrvidpamAKVVLIEGGSRVL-GAFNEELSAYAQRA 228
Cdd:COG1251  141 PGKR------------VVVIGGGLIGLEAAAALRKR------G---------LEVTVVERAPRLLpRQLDEEAGALLQRL 193

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 229 LEKLGVTVHVGNPVTACHAD----GVEFA-GHSLRAKTIIWAAGVQasPAAKWL-NAPADRAGRLAVNPDLTAPDhPEIF 302
Cdd:COG1251  194 LEALGVEVRLGTGVTEIEGDdrvtGVRLAdGEELPADLVVVAIGVR--PNTELArAAGLAVDRGIVVDDYLRTSD-PDIY 270

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 398218360 303 VIGDTATVANGDKGNVP-GIAPAAKQQGAHVAKTikarLAGDNEP 346
Cdd:COG1251  271 AAGDCAEHPGPVYGRRVlELVAPAYEQARVAAAN----LAGGPAA 311
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 30-344 3.27e-33

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 127.23  E-value: 3.27e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  30 RKADIDITLIDQRNHHLFQP--LLYQVATSTLATSEIAW-PIRHLLRKfkNVKTLLGT-VDHVDTAKRTVSTVDGETIPY 105
Cdd:COG0446    2 LGPDAEITVIEKGPHHSYQPcgLPYYVGGGIKDPEDLLVrTPESFERK--GIDVRTGTeVTAIDPEAKTVTLRDGETLSY 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 106 DTLVLATGARhayfghDDWEPFaPG--------LKTLEDATMIRRRIltafekaerepdpaKREELLTFVIIGGGPTGVE 177
Cdd:COG0446   80 DKLVLATGAR------PRPPPI-PGldlpgvftLRTLDDADALREAL--------------KEFKGKRAVVIGGGPIGLE 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 178 IAGTLADLARdtlkgdfrvidpamaKVVLIEGGSRVLGAFNEELSAYAQRALEKLGVTVHVGNPVTACHADG---VEFA- 253
Cdd:COG0446  139 LAEALRKRGL---------------KVTLVERAPRLLGVLDPEMAALLEEELREHGVELRLGETVVAIDGDDkvaVTLTd 203

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 254 GHSLRAKTIIWAAGVQasPAAKWL-NAPA--DRAGRLAVNPDL-TapDHPEIFVIGDTATVAN---GDKGNVPGIAPAAK 326
Cdd:COG0446  204 GEEIPADLVVVAPGVR--PNTELAkDAGLalGERGWIKVDETLqT--SDPDVYAAGDCAEVPHpvtGKTVYIPLASAANK 279

                        330
                 ....*....|....*...
gi 398218360 327 QqgahvaktikARLAGDN 344
Cdd:COG0446  280 Q----------GRVAAEN 287
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 90-353 1.83e-20

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 93.23  E-value: 1.83e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  90 TAKRTVSTVDGETIPYDTLVLATGARhayfghddwePFAPGLKTLEDAtmirrRILT---AFEKAERepdPAKreelltF 166
Cdd:COG1249  116 VDPHTVEVTGGETLTADHIVIATGSR----------PRVPPIPGLDEV-----RVLTsdeALELEEL---PKS------L 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 167 VIIGGGPTGVEIAGTLADLardtlkGdfrvidpamAKVVLIEGGSRVLGAFNEELSAYAQRALEKLGVTVHVGNPVTACH 246
Cdd:COG1249  172 VVIGGGYIGLEFAQIFARL------G---------SEVTLVERGDRLLPGEDPEISEALEKALEKEGIDILTGAKVTSVE 236

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 247 ADG----VEFAG----HSLRAKTIIWAAGVQasPAAKWLNAPA-----DRAGRLAVNPDL-TAPDHpeIFVIGDtatVAN 312
Cdd:COG1249  237 KTGdgvtVTLEDgggeEAVEADKVLVATGRR--PNTDGLGLEAagvelDERGGIKVDEYLrTSVPG--IYAIGD---VTG 309

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 398218360 313 GdkgnvPGIAPAAKQQGAHVAKTIkarlAGDNePKPFRYRH 353
Cdd:COG1249  310 G-----PQLAHVASAEGRVAAENI----LGKK-PRPVDYRA 340
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
14-308 3.86e-20

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 91.52  E-value: 3.86e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  14 VIVGAGFGGLVTVQNLRK--ADIDITLI-----DQRNH----HLFQplLYQVAT--STLATSEIAwpirhllRKFkNVKT 80
Cdd:PRK04965   6 VIIGSGFAARQLVKNIRKqdAHIPITLItadsgDEYNKpdlsHVFS--QGQRADdlTRQSAGEFA-------EQF-NLRL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  81 LLGT-VDHVDTAKRTVsTVDGETIPYDTLVLATGARhayfghddwePFAPGLKTleDATMIRRRILTAFEKAEREPDPAK 159
Cdd:PRK04965  76 FPHTwVTDIDAEAQVV-KSQGNQWQYDKLVLATGAS----------AFVPPIPG--RELMLTLNSQQEYRAAETQLRDAQ 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 160 ReelltFVIIGGGPTGVEIAgtlADLARdtlkgdfrvidpAMAKVVLIEGGSRVLGAF-NEELSAYAQRALEKLGVTVHV 238
Cdd:PRK04965 143 R-----VLVVGGGLIGTELA---MDLCR------------AGKAVTLVDNAASLLASLmPPEVSSRLQHRLTEMGVHLLL 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 239 GNPVTAC--HADGVEF---AGHSLRAKTIIWAAGVQASPAAkwlnapADRAGrLAVNPDLTAPDH-----PEIFVIGDTA 308
Cdd:PRK04965 203 KSQLQGLekTDSGIRAtldSGRSIEVDAVIAAAGLRPNTAL------ARRAG-LAVNRGIVVDSYlqtsaPDIYALGDCA 275
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 13-371 1.16e-17

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 85.65  E-value: 1.16e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360   13 LVIVGAGFGGLVTVQNLRKAD---IDITLIDQRNHHLFQPLLYQVATSTLAT-SEIAWPIRHLLRKfKNVKTLLG-TVDH 87
Cdd:TIGR02374   1 LVLVGNGMAGHRCIEEVLKLNrhmFEITIFGEEPHPNYNRILLSSVLQGEADlDDITLNSKDWYEK-HGITLYTGeTVIQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360   88 VDTAKRTVSTVDGETIPYDTLVLATGArHAYF----GHDdwEPFAPGLKTLEDATMIRrriltafEKAEREPDPAkreel 163
Cdd:TIGR02374  80 IDTDQKQVITDAGRTLSYDKLILATGS-YPFIlpipGAD--KKGVYVFRTIEDLDAIM-------AMAQRFKKAA----- 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  164 ltfvIIGGGPTGVEIAGTLADLARDTlkgdfRVIDPA---MAKvVLIEGGSRVLgafneelsayaQRALEKLGVTVHVGN 240
Cdd:TIGR02374 145 ----VIGGGLLGLEAAVGLQNLGMDV-----SVIHHApglMAK-QLDQTAGRLL-----------QRELEQKGLTFLLEK 203

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  241 P----VTACHADGVEFA-GHSLRAKTIIWAAGVQasPAAKWLNAPADRAGRLAVNPDLTAPDHPEIFVIGDTATVangdK 315
Cdd:TIGR02374 204 DtveiVGATKADRIRFKdGSSLEADLIVMAAGIR--PNDELAVSAGIKVNRGIIVNDSMQTSDPDIYAVGECAEH----N 277

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 398218360  316 GNVPG-IAPAAKQqgahvAKTIKARLAGdNEPKPFRyrhAGDLATIGKRAAVTDFGF 371
Cdd:TIGR02374 278 GRVYGlVAPLYEQ-----AKVLADHICG-VECEEYE---GSDLSAKLKLLGVDVWSA 325
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 68-352 9.77e-12

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 66.35  E-value: 9.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  68 IRHLLRKFKNVKTLLGTVDHVDTakRTVStVDGETIPYDTLVLATGARhayfghddwEPFAPGLKTLEDAtmirrRILTA 147
Cdd:PRK06292  97 VVEGLEKKPKIDKIKGTARFVDP--NTVE-VNGERIEAKNIVIATGSR---------VPPIPGVWLILGD-----RLLTS 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 148 FEKAEREPDPAKreelltFVIIGGGPTGVEIAGTLADLArdtlkgdfrvidpamAKVVLIEGGSRVLGAFNEELSAYAQR 227
Cdd:PRK06292 160 DDAFELDKLPKS------LAVIGGGVIGLELGQALSRLG---------------VKVTVFERGDRILPLEDPEVSKQAQK 218

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 228 ALEKlGVTVHVGNPVTACHADGVEF--------AGHSLRAKTIIWAAGVQA---SPAAKWLNAPADRAGRLAVNPdLTAP 296
Cdd:PRK06292 219 ILSK-EFKIKLGAKVTSVEKSGDEKveelekggKTETIEADYVLVATGRRPntdGLGLENTGIELDERGRPVVDE-HTQT 296

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 398218360 297 DHPEIFVIGDtatvANGDkgnvPGIAPAAKQQGaHVAktikARLAGDNEPKPFRYR 352
Cdd:PRK06292 297 SVPGIYAAGD----VNGK----PPLLHEAADEG-RIA----AENAAGDVAGGVRYH 339
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 70-251 2.72e-11

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 65.17  E-value: 2.72e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  70 HLLRKFKnVKTLLGTVDHVDTAKRTVSTVDGE-TIPYDTLVLATGARhayfghddwePFA-PGLKTLEdatmirRRILTA 147
Cdd:PRK06416 100 GLLKKNK-VDIIRGEAKLVDPNTVRVMTEDGEqTYTAKNIILATGSR----------PRElPGIEIDG------RVIWTS 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 148 FEKAEREPDPAKreelltFVIIGGGPTGVEIAGTLADLArdtlkgdfrvidpamAKVVLIEGGSRVLGAFNEELSAYAQR 227
Cdd:PRK06416 163 DEALNLDEVPKS------LVVIGGGYIGVEFASAYASLG---------------AEVTIVEALPRILPGEDKEISKLAER 221

                        170       180
                 ....*....|....*....|....*.
gi 398218360 228 ALEKLGVTVHVGNPVTAC--HADGVE 251
Cdd:PRK06416 222 ALKKRGIKIKTGAKAKKVeqTDDGVT 247
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 167-250 3.04e-11

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 59.14  E-value: 3.04e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  167 VIIGGGPTGVEIAGTLADLArdtlkgdfrvidpamAKVVLIEGGSRVLGAFNEELSAYAQRALEKLGVTVHVGNPVTACH 246
Cdd:pfam00070   3 VVVGGGYIGLELAGALARLG---------------SKVTVVERRDRLLPGFDPEIAKILQEKLEKNGIEFLLNTTVEAIE 67


                  ....
gi 398218360  247 ADGV 250
Cdd:pfam00070  68 GNGD 71
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 12-115 1.01e-10

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 62.52  E-value: 1.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  12 RLVIVGAGFGGLVTVQNLRKADIDITLIDqRNHHLFQPLLYqvatstlatsEIAWPIRHLLRKfKNVKTLLG-TVDHVD- 89
Cdd:COG0446  126 RAVVIGGGPIGLELAEALRKRGLKVTLVE-RAPRLLGVLDP----------EMAALLEEELRE-HGVELRLGeTVVAIDg 193

                         90       100
                 ....*....|....*....|....*.
gi 398218360  90 TAKRTVSTVDGETIPYDTLVLATGAR 115
Cdd:COG0446  194 DDKVAVTLTDGEEIPADLVVVAPGVR 219
PRK14989 PRK14989
nitrite reductase subunit NirD; Provisional
 77-309 1.67e-10

nitrite reductase subunit NirD; Provisional


Pssm-ID: 184951 [Multi-domain]  Cd Length: 847  Bit Score: 63.21  E-value: 1.67e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  77 NVKTLLGT-VDHVDTAKRTVSTVDGETIPYDTLVLATGARhayfghddwePFAPGLK-----------TLEDatmirrri 144
Cdd:PRK14989  73 GIKVLVGErAITINRQEKVIHSSAGRTVFYDKLIMATGSY----------PWIPPIKgsetqdcfvyrTIED-------- 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 145 LTAFEKAEREpdpAKREelltfVIIGGGPTGVEIAGTLADLARDTlkgdfRVIDPA---MAKVVLIEGGSRVlgafneel 221
Cdd:PRK14989 135 LNAIEACARR---SKRG-----AVVGGGLLGLEAAGALKNLGVET-----HVIEFApmlMAEQLDQMGGEQL-------- 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 222 sayaQRALEKLGVTVHVGNPVTACHADGVE------FA-GHSLRAKTIIWAAGVQASPA-AKWLNAPADRAGRLAVNPDL 293
Cdd:PRK14989 194 ----RRKIESMGVRVHTSKNTLEIVQEGVEarktmrFAdGSELEVDFIVFSTGIRPQDKlATQCGLAVAPRGGIVINDSC 269

                        250
                 ....*....|....*.
gi 398218360 294 TAPDhPEIFVIGDTAT 309
Cdd:PRK14989 270 QTSD-PDIYAIGECAS 284
PRK06370 PRK06370
FAD-containing oxidoreductase;
72-249 1.46e-08

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 56.36  E-value: 1.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  72 LRKFKNVKTLLGTVdhVDTAKRTVStVDGETIPYDTLVLATGARhayfghddwePFAPGLKTLEDAtmirrRILTA---F 148
Cdd:PRK06370 104 LRGLEGVDVFRGHA--RFESPNTVR-VGGETLRAKRIFINTGAR----------AAIPPIPGLDEV-----GYLTNetiF 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 149 EKAERepdPAKreelltFVIIGGGPTGVEIAGTLADLArdtlkgdfrvidpamAKVVLIEGGSRVLGAFNEELSAYAQRA 228
Cdd:PRK06370 166 SLDEL---PEH------LVIIGGGYIGLEFAQMFRRFG---------------SEVTVIERGPRLLPREDEDVAAAVREI 221

                        170       180
                 ....*....|....*....|.
gi 398218360 229 LEKLGVTVHVGNPVTACHADG 249
Cdd:PRK06370 222 LEREGIDVRLNAECIRVERDG 242
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 6-343 1.25e-07

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 53.33  E-value: 1.25e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360   6 TVAPRHRLVIVGAGFGGLVTVQNLRKADIDITLIDQR--------------------NHHL---FQPllYQVATSTLAT- 61
Cdd:COG2072    2 AATEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKAddvggtwrdnrypglrldtpSHLYslpFFP--NWSDDPDFPTg 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  62 SEIAWPIRHLLRKFK-NVKTLLGT-VDHV----DTAKRTVSTVDGETIPYDTLVLATGarhaYFghddWEPFAPGLKTLE 135
Cdd:COG2072   80 DEILAYLEAYADKFGlRRPIRFGTeVTSArwdeADGRWTVTTDDGETLTARFVVVATG----PL----SRPKIPDIPGLE 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 136 DATMirrRILTAfekAE-REPD--PAKReelltFVIIGGGPTGVEIAGTLADLARDTL--------KGDFRVIDPAMAKV 204
Cdd:COG2072  152 DFAG---EQLHS---ADwRNPVdlAGKR-----VLVVGTGASAVQIAPELARVAAHVTvfqrtppwVLPRPNYDPERGRP 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 205 VLIEGGSRVLGAFNEELSAYAQR---------ALEKL------------------------GVTVhVGNPVTACHADGVE 251
Cdd:COG2072  221 ANYLGLEAPPALNRRDARAWLRRllraqvkdpELGLLtpdyppgckrpllstdyyealrrgNVEL-VTGGIERITEDGVV 299

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 252 FA-GHSLRAKTIIWAAGVQASPAakWLNAPA--DRAGRLAVNPDL--TAPDHPEIFVIGDTATVANGdkgnvpGIAPAAK 326
Cdd:COG2072  300 FAdGTEHEVDVIVWATGFRADLP--WLAPLDvrGRDGRSGPRAYLgvVVPGFPNLFFLGPNSPSGHS------SLTLGAE 371

                        410
                 ....*....|....*..
gi 398218360 327 QQGAHVAKTIKARLAGD 343
Cdd:COG2072  372 RQARYIARLIAHMRRRG 388
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 105-346 1.63e-07

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 53.12  E-value: 1.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 105 YDTLVLATGARHAY--FGHDDWEPFApGLKTLEDATMIRRRIltafekaerepdpaKREELLTFVIIGGGPTGVEIAGTL 182
Cdd:PRK09564 104 YDKLMIATGARPIIppIKNINLENVY-TLKSMEDGLALKELL--------------KDEEIKNIVIIGAGFIGLEAVEAA 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 183 ADLARDtlkgdfrvidpamakVVLIEGGSRVLG-AFNEELSAYAQRALEKLGVTVHVGNPVTACHAD----GVEFAGHSL 257
Cdd:PRK09564 169 KHLGKN---------------VRIIQLEDRILPdSFDKEITDVMEEELRENGVELHLNEFVKSLIGEdkveGVVTDKGEY 233

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 258 RAKTIIWAAGVQ-ASPAAKWLNAPADRAGRLAVNpDLTAPDHPEIFVIGDTATVAN---GDKGNVPgIAPAAKQQGAHVA 333
Cdd:PRK09564 234 EADVVIVATGVKpNTEFLEDTGLKTLKNGAIIVD-EYGETSIENIYAAGDCATIYNivsNKNVYVP-LATTANKLGRMVG 311

                        250
                 ....*....|...
gi 398218360 334 KtikaRLAGDNEP 346
Cdd:PRK09564 312 E----NLAGRHVS 320
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
167-333 4.23e-07

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 52.08  E-value: 4.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 167 VIIGGGPTGVEIAGTLADLarDTlkgdfrvidpamaKVVLIEGGSRVLGAFNEELSAYAQRALEKLGVTVHVGNPVTAC- 245
Cdd:PRK05249 179 IIYGAGVIGCEYASIFAAL--GV-------------KVTLINTRDRLLSFLDDEISDALSYHLRDSGVTIRHNEEVEKVe 243

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 246 -HADGVEFA---GHSLRAKTIIWAAGVQASPAAkwLNAP-----ADRAGRLAVNPDL-TAPDHpeIFVIGDtatvangdk 315
Cdd:PRK05249 244 gGDDGVIVHlksGKKIKADCLLYANGRTGNTDG--LNLEnagleADSRGQLKVNENYqTAVPH--IYAVGD--------- 310

                        170       180
                 ....*....|....*....|.
gi 398218360 316 gnV---PGIAPAAKQQGAHVA 333
Cdd:PRK05249 311 --VigfPSLASASMDQGRIAA 329
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
11-306 4.45e-07

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 51.27  E-value: 4.45e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  11 HRLVIVGAGFGGLVTVQNLRKADIDITLIDQRnhhlfqpllyQVATSTLATSEI------AWPIR--HLLRKFK------ 76
Cdd:COG0492    1 YDVVIIGAGPAGLTAAIYAARAGLKTLVIEGG----------EPGGQLATTKEIenypgfPEGISgpELAERLReqaerf 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  77 NVKTLLGTVDHVDTAKR--TVSTVDGETIPYDTLVLATGARHAYFGHDDWEPFapglktledatmiRRRILTAFEKAERE 154
Cdd:COG0492   71 GAEILLEEVTSVDKDDGpfRVTTDDGTEYEAKAVIIATGAGPRKLGLPGEEEF-------------EGRGVSYCATCDGF 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 155 PDPAKReelltFVIIGGGPTGVEIAGTLADLArdtlkgdfrvidpamAKVVLIeggsrvlgAFNEELSA---YAQRALEK 231
Cdd:COG0492  138 FFRGKD-----VVVVGGGDSALEEALYLTKFA---------------SKVTLI--------HRRDELRAskiLVERLRAN 189

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 232 LGVTVHVGNPVTACHAD----GVEFAGHSLRAKTIIWAAGV----QASPAAKWL---NAPADRAGRLAVNPDlTAPDHPE 300
Cdd:COG0492  190 PKIEVLWNTEVTEIEGDgrveGVTLKNVKTGEEKELEVDGVfvaiGLKPNTELLkglGLELDEDGYIVVDED-METSVPG 268


                 ....*.
gi 398218360 301 IFVIGD 306
Cdd:COG0492  269 VFAAGD 274
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
5-115 2.10e-06

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 49.75  E-value: 2.10e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360   5 ETVAPRHRLVIVGAGFGGLVTVQNLRKADIDITLIDQRNHhlfqPLLYQVATstlATSEIawpIRHLLRKfKNVKTLLGT 84
Cdd:COG1251  137 AALAPGKRVVVIGGGLIGLEAAAALRKRGLEVTVVERAPR----LLPRQLDE---EAGAL---LQRLLEA-LGVEVRLGT 205

                         90       100       110
                 ....*....|....*....|....*....|....
gi 398218360  85 -VDHV--DTAKRTVSTVDGETIPYDTLVLATGAR 115
Cdd:COG1251  206 gVTEIegDDRVTGVRLADGEELPADLVVVAIGVR 239
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 13-308 6.68e-06

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 48.00  E-value: 6.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  13 LVIVGAGFGGLVTVQNLRKA--DIDITLIDQRNHHLFQ-PLLyqvATSTLATSEIAwPIRHLLRKF---KNVKTLLG-TV 85
Cdd:PRK09754   6 IIIVGGGQAAAMAAASLRQQgfTGELHLFSDERHLPYErPPL---SKSMLLEDSPQ-LQQVLPANWwqeNNVHLHSGvTI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  86 DHVDTAKRTVSTVDGETIPYDTLVLATGARHAYFGHDDwepfAPG-----LKTLEDATMIRRRIltafekaerepDPAKR 160
Cdd:PRK09754  82 KTLGRDTRELVLTNGESWHWDQLFIATGAAARPLPLLD----ALGercftLRHAGDAARLREVL-----------QPERS 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 161 eelltFVIIGGGPTGVEIAGTLADLArdtlkgdfrvidpamAKVVLIEGGSRVLGAFNEEL--SAYAQRALEKlGVTVHV 238
Cdd:PRK09754 147 -----VVIVGAGTIGLELAASATQRR---------------CKVTVIELAATVMGRNAPPPvqRYLLQRHQQA-GVRILL 205

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 398218360 239 GNP-VTACHADGVEF---AGHSLRAKTIIWAAGVQASPAAKwLNAPADRAGRLAVNPDLTAPDhPEIFVIGDTA 308
Cdd:PRK09754 206 NNAiEHVVDGEKVELtlqSGETLQADVVIYGIGISANDQLA-REANLDTANGIVIDEACRTCD-PAIFAGGDVA 277
PRK07251 PRK07251
FAD-containing oxidoreductase;
68-267 2.58e-05

FAD-containing oxidoreductase;


Pssm-ID: 180907 [Multi-domain]  Cd Length: 438  Bit Score: 46.28  E-value: 2.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  68 IRHLLRKfKNVKTLLGT-VDHVDTAKRTVST--------VDGETIPYDTLVLATGARHAYFghddwePFaPGLKTLE--- 135
Cdd:PRK07251  74 VTSRLRG-KNYAMLAGSgVDLYDAEAHFVSNkvievqagDEKIELTAETIVINTGAVSNVL------PI-PGLADSKhvy 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 136 DATMIrrriltafEKAEREPDpakreellTFVIIGGGPTGVEIAGTLADLArdtlkgdfrvidpamAKVVLIEGGSRVLG 215
Cdd:PRK07251 146 DSTGI--------QSLETLPE--------RLGIIGGGNIGLEFAGLYNKLG---------------SKVTVLDAASTILP 194

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 398218360 216 AFNEELSAYAQRALEKLGVTVHVGNPVTACHADG----VEFAGHSLRAKTIIWAAG 267
Cdd:PRK07251 195 REEPSVAALAKQYMEEDGITFLLNAHTTEVKNDGdqvlVVTEDETYRFDALLYATG 250
PRK13512 PRK13512
coenzyme A disulfide reductase; Provisional
 12-343 5.65e-05

coenzyme A disulfide reductase; Provisional


Pssm-ID: 184103 [Multi-domain]  Cd Length: 438  Bit Score: 45.16  E-value: 5.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  12 RLVIVGAGFGGLVTVQNLRK--ADIDITLIDQRNHHLFQ--PLLYQVATSTLATSEI--AWPIRHLLRKFKNVKTLlGTV 85
Cdd:PRK13512   3 KIIVVGAVAGGATCASQIRRldKESDIIIFEKDRDMSFAncALPYYIGEVVEDRKYAlaYTPEKFYDRKQITVKTY-HEV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360  86 DHVDTAKRTVSTVDGET-----IPYDTLVLATGARHAYFGHDdwEPFAPGLKTLEDATMIRRRIltafekaerEPDPAKR 160
Cdd:PRK13512  82 IAINDERQTVTVLNRKTneqfeESYDKLILSPGASANSLGFE--SDITFTLRNLEDTDAIDQFI---------KANQVDK 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 161 EelltfVIIGGGPTGVEIAGTLADlardtlkgdfRVIDPAmakvvLIEGGSRVLGAFNEELSAYAQRALEKLGVTVHVGN 240
Cdd:PRK13512 151 A-----LVVGAGYISLEVLENLYE----------RGLHPT-----LIHRSDKINKLMDADMNQPILDELDKREIPYRLNE 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398218360 241 PVTACHADGVEF-AGHSLRAKTIIWAAGVQasPAAKWL---NAPADRAGRLAVNpDLTAPDHPEIFVIGDTATvANGDKG 316
Cdd:PRK13512 211 EIDAINGNEVTFkSGKVEHYDMIIEGVGTH--PNSKFIessNIKLDDKGFIPVN-DKFETNVPNIYAIGDIIT-SHYRHV 286

                        330       340
                 ....*....|....*....|....*...
gi 398218360 317 NVPGIAPAAkqQGAHVAKTIKA-RLAGD 343
Cdd:PRK13512 287 DLPASVPLA--WGAHRAASIVAeQIAGN 312
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
15-44 1.24e-04

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 39.82  E-value: 1.24e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 398218360   15 IVGAGFGGLVTVQNLRKADIDITLIDQRNH 44
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDR 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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