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Conserved domains on  [gi|351701062|gb|EHB03981|]
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hypothetical protein GW7_15988, partial [Heterocephalus glaber]

Protein Classification

TBC domain-containing protein; TBC and TLD domain-containing protein( domain architecture ID 10633145)

TBC (Tre-2, BUB2p, Cdc16p) domain-containing protein may perform a GTP-activator activity on Rab-like GTPases| TBC (Tre-2/Bub2/Cdc1) and TLD domain-containing protein may function as a GTPase activator protein of Rab-like small GTPases; similar to Drosophila melanogaster GTPase-activating protein skywalker

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BROMI pfam14961
Broad-minded protein; Broad-minded protein (BROMI) interacts with cell cycle-related kinase ...
 12-1301 0e+00

Broad-minded protein; Broad-minded protein (BROMI) interacts with cell cycle-related kinase (CCRK), together these proteins regulate ciliary membrane and axonemal growth.


:

Pssm-ID: 464406  Cd Length: 1292  Bit Score: 2311.65  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062    12 LRAMLRQLIQSVKERVTGAPSLQCAKEVLLRLEETDANFHNYELVRYLRQHICSTLGPMIEEEMEKCASEKNQGEEPGYD 91
Cdd:pfam14961    1 LQSLLRQLLQSVKEKISGAPSVECAEEILLHLEETDENFHNYEFVKYLRQYIESTLGSVIEEETEKCTSEEGQGEGSGQD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062    92 TVVQCVLARVQESAQYKDMMHSLKGVMTAMVGCMSSGFEEQEeeeeeTQRPERQRKAHREKGSRHCTDSCSDSDSSFSQS 171
Cdd:pfam14961   81 TLVQAVTKRTRESKEYKEMMHSLKNVMMVVVESLINKFEEDQ-----MRKEEMHRKSQHEQLSSHYTDNCSDSDSSFNQS 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   172 YKF-CPGKLQLIVDQLDPRQPKEVRHEALQMLCSAPPSDILGCENGASLCQRLTAALSDPDPVLSDRILKFYAQAFILLP 250
Cdd:pfam14961  156 YTFmSQEQLQLIAEKLDPRQPKEVRWEALQTLCHAPPSDVLSCESWTSLRRNLMAALSDPDPALSDKILRFYAKTFSSSP 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   251 LHMTNEIYTSLAKYLELYFLSRESHIPTLSAGVDVNNPDVTRLLKKVRLLSEYQKEAPSFWIRHPEKYMEEIVESTLSLL 330
Cdd:pfam14961  236 LNITREIYTSLAKHLESYFLSSKLSFPSLSAGLDINNPDVARLLKKIRLLNEFQKEVPSFWIRHPEKYMEEIVESTLSLL 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   331 SAEHAPG--PLLSPKILDPICFFALVDTKAVWFKKWTHAYYSRTTVLKLLEKKYKSLIIAAVQQCIQYLELCETSKADLI 408
Cdd:pfam14961  316 SLHHEQGlnSPGSDKVLDPIYFLALLDIKATWFKKWMHGYYSRTVVLRLLEKKYKSLIVAAVQQCIDYFESCEASVDKTT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   409 ----LGHSKHCGDKQKTlYYSGQEVQYIYFIHSLCLLGRLLIYTQGRKLFPIKLKNRHDSVSLTDLVVLFIRLIYYSPSH 484
Cdd:pfam14961  396 eishSSHQQHIGNKQRT-FYTGKELQYIYFVHSLCLLGRLLIYTQGRKLFPIKLKNRKDPVSLTDLLVLLIRLIYYSPSL 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   485 PDTTPDVDSEDYSPASMVTEILQILCDQKECAMECLYSSTVISTLLQPIHNLMKGNEAAPHCSETALIHAAGVLARIASA 564
Cdd:pfam14961  475 PKETPHVGSDNYSPASLVMEVLQILCDRKECAAECLYQDTVIETLLQPIITLLNGKEAKLNCSETTLIHIADILARIAST 554

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   565 EEGLALLLYGEDMSPSEEDSLTGAHVTAQFTKRLLEGEVPGLAGSALLPAVQRAFVSLCCQMCGTCEGLQALLPYSLHEA 644
Cdd:pfam14961  555 ERGLSLLLYGGNLSSAEEESISAAHVIVQFTKKLLDKEIPVLSGSELLPSLKGAFIFVCRQMYNTCEGLQVLLPYGLHES 634

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   645 VAQARRKASLPSEGIPTPVLGSHSVSSVSQGSQNIMAWEESLLDDLLNFAATPKGLLLLHRAGVINDCVTFMSNQYAENL 724
Cdd:pfam14961  635 IAEAWKKASLLSERVPTPVPGADCSSSVSQESQNVVVWEETLLDNLLNFAATPKGLLLLQQTGAINECVTYMFSRFTKKL 714

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   725 QVSRQKKVGYGVLVTQVASTAAGAAVLRDSGFVSALVAGLWSSLECGGEDTMVNHPRPTPVEPIDRSCQKSFLALVSLLS 804
Cdd:pfam14961  715 QVSRCEKFGYGVMVTQVAATAPGAVALQSSGFVRALVLELWSVLECGRDDVRVTHPKSTPVDPIDRSCQKSFLALVNLLS 794

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   805 S-PAGYELLGLQDLPNRAEYSLHELPTCVTDIIDRLIILNSEAKIHSLFNYEQSHIFGLRLLSVMCCDLDLLLLLEAQYQ 883
Cdd:pfam14961  795 SyPAVYELLGNQELPNKTEYSLREMPTSIIDLIDRLIIINSEAKIHSLFNYEQSHTFGLRLLSVLCCNLDSLLLLESQYN 874

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   884 VSRVLLRAQEENISEVSGSHRGFIIDGLSVERNHVLVRMNLIGGPLERTVPPRTLDKGENPYPWPMFSSYPLPHCYRSKA 963
Cdd:pfam14961  875 ISEVLLQAQKENVTEPSGSEGEFIIDGLSVERNHILVRINLIGGPSERILPPRALQKGEDPYPWPMFSSYPLPKCYLPDV 954

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   964 TRNPDIKQDADLSQLLSCFMISDKQTEWVENCQRQFCTAMKSKGHVISGGALGELLEKFVLHLTEIPAECYFPSVEYTAA 1043
Cdd:pfam14961  955 PRITDTKQDSELSKFLSSSKNPEKQAEWMENCRRQFCKIMKTKPDTISGGVLAELLEKFVLHLSESPSECYFSSTEYKAA 1034

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062  1044 DADVRSESLSSVQQLGVRMAISYGKFLNLLNDGAESDLALVLKHCERFLKQQQAPVKSSLFCLQGAYAGHDWFVSSLFLM 1123
Cdd:pfam14961 1035 DADVKNASLSSVQQLGVKMTIRYGKYLNLLKEDAENDLCLVLKHCEQFLKQQQVKVSSSLRCLQGGYPGHDWFASSVFLI 1114

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062  1124 LSGDGERTLRFLLRFSRLLASALLWLPRLHLSRYLPADTVASGIHPAYFCSAHCTEMLLKTEVPLVYSAFHMSGFAPSQI 1203
Cdd:pfam14961 1115 MSGDKERSLSFLLRFSHLLVSAFLWPPRLHASIHLPADTAESGIHPVYSCTAHYVEMLLKAEVPLVFSAFRMSGFTPSQI 1194

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062  1204 CLQWITQCFWNYLDWIEICHYIATCVFLGPDYQVYICIAIFKHLQQEILQHTQTQDLQVFLKEEALRGFRVSDHFEYMEM 1283
Cdd:pfam14961 1195 CLQWLTQCFWNYLDWTEICHYIATCIFMGPDYQVYMCISILKHLQQEILQHTQTQDLQVFLKEEPIHGFRVSNYLEYMES 1274

                         1290
                   ....*....|....*...
gi 351701062  1284 LERNYRPALLRDMRAIRE 1301
Cdd:pfam14961 1275 LEQTYRPMVLTDMRNIRV 1292
 
Name Accession Description Interval E-value
BROMI pfam14961
Broad-minded protein; Broad-minded protein (BROMI) interacts with cell cycle-related kinase ...
 12-1301 0e+00

Broad-minded protein; Broad-minded protein (BROMI) interacts with cell cycle-related kinase (CCRK), together these proteins regulate ciliary membrane and axonemal growth.


Pssm-ID: 464406  Cd Length: 1292  Bit Score: 2311.65  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062    12 LRAMLRQLIQSVKERVTGAPSLQCAKEVLLRLEETDANFHNYELVRYLRQHICSTLGPMIEEEMEKCASEKNQGEEPGYD 91
Cdd:pfam14961    1 LQSLLRQLLQSVKEKISGAPSVECAEEILLHLEETDENFHNYEFVKYLRQYIESTLGSVIEEETEKCTSEEGQGEGSGQD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062    92 TVVQCVLARVQESAQYKDMMHSLKGVMTAMVGCMSSGFEEQEeeeeeTQRPERQRKAHREKGSRHCTDSCSDSDSSFSQS 171
Cdd:pfam14961   81 TLVQAVTKRTRESKEYKEMMHSLKNVMMVVVESLINKFEEDQ-----MRKEEMHRKSQHEQLSSHYTDNCSDSDSSFNQS 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   172 YKF-CPGKLQLIVDQLDPRQPKEVRHEALQMLCSAPPSDILGCENGASLCQRLTAALSDPDPVLSDRILKFYAQAFILLP 250
Cdd:pfam14961  156 YTFmSQEQLQLIAEKLDPRQPKEVRWEALQTLCHAPPSDVLSCESWTSLRRNLMAALSDPDPALSDKILRFYAKTFSSSP 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   251 LHMTNEIYTSLAKYLELYFLSRESHIPTLSAGVDVNNPDVTRLLKKVRLLSEYQKEAPSFWIRHPEKYMEEIVESTLSLL 330
Cdd:pfam14961  236 LNITREIYTSLAKHLESYFLSSKLSFPSLSAGLDINNPDVARLLKKIRLLNEFQKEVPSFWIRHPEKYMEEIVESTLSLL 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   331 SAEHAPG--PLLSPKILDPICFFALVDTKAVWFKKWTHAYYSRTTVLKLLEKKYKSLIIAAVQQCIQYLELCETSKADLI 408
Cdd:pfam14961  316 SLHHEQGlnSPGSDKVLDPIYFLALLDIKATWFKKWMHGYYSRTVVLRLLEKKYKSLIVAAVQQCIDYFESCEASVDKTT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   409 ----LGHSKHCGDKQKTlYYSGQEVQYIYFIHSLCLLGRLLIYTQGRKLFPIKLKNRHDSVSLTDLVVLFIRLIYYSPSH 484
Cdd:pfam14961  396 eishSSHQQHIGNKQRT-FYTGKELQYIYFVHSLCLLGRLLIYTQGRKLFPIKLKNRKDPVSLTDLLVLLIRLIYYSPSL 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   485 PDTTPDVDSEDYSPASMVTEILQILCDQKECAMECLYSSTVISTLLQPIHNLMKGNEAAPHCSETALIHAAGVLARIASA 564
Cdd:pfam14961  475 PKETPHVGSDNYSPASLVMEVLQILCDRKECAAECLYQDTVIETLLQPIITLLNGKEAKLNCSETTLIHIADILARIAST 554

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   565 EEGLALLLYGEDMSPSEEDSLTGAHVTAQFTKRLLEGEVPGLAGSALLPAVQRAFVSLCCQMCGTCEGLQALLPYSLHEA 644
Cdd:pfam14961  555 ERGLSLLLYGGNLSSAEEESISAAHVIVQFTKKLLDKEIPVLSGSELLPSLKGAFIFVCRQMYNTCEGLQVLLPYGLHES 634

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   645 VAQARRKASLPSEGIPTPVLGSHSVSSVSQGSQNIMAWEESLLDDLLNFAATPKGLLLLHRAGVINDCVTFMSNQYAENL 724
Cdd:pfam14961  635 IAEAWKKASLLSERVPTPVPGADCSSSVSQESQNVVVWEETLLDNLLNFAATPKGLLLLQQTGAINECVTYMFSRFTKKL 714

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   725 QVSRQKKVGYGVLVTQVASTAAGAAVLRDSGFVSALVAGLWSSLECGGEDTMVNHPRPTPVEPIDRSCQKSFLALVSLLS 804
Cdd:pfam14961  715 QVSRCEKFGYGVMVTQVAATAPGAVALQSSGFVRALVLELWSVLECGRDDVRVTHPKSTPVDPIDRSCQKSFLALVNLLS 794

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   805 S-PAGYELLGLQDLPNRAEYSLHELPTCVTDIIDRLIILNSEAKIHSLFNYEQSHIFGLRLLSVMCCDLDLLLLLEAQYQ 883
Cdd:pfam14961  795 SyPAVYELLGNQELPNKTEYSLREMPTSIIDLIDRLIIINSEAKIHSLFNYEQSHTFGLRLLSVLCCNLDSLLLLESQYN 874

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   884 VSRVLLRAQEENISEVSGSHRGFIIDGLSVERNHVLVRMNLIGGPLERTVPPRTLDKGENPYPWPMFSSYPLPHCYRSKA 963
Cdd:pfam14961  875 ISEVLLQAQKENVTEPSGSEGEFIIDGLSVERNHILVRINLIGGPSERILPPRALQKGEDPYPWPMFSSYPLPKCYLPDV 954

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   964 TRNPDIKQDADLSQLLSCFMISDKQTEWVENCQRQFCTAMKSKGHVISGGALGELLEKFVLHLTEIPAECYFPSVEYTAA 1043
Cdd:pfam14961  955 PRITDTKQDSELSKFLSSSKNPEKQAEWMENCRRQFCKIMKTKPDTISGGVLAELLEKFVLHLSESPSECYFSSTEYKAA 1034

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062  1044 DADVRSESLSSVQQLGVRMAISYGKFLNLLNDGAESDLALVLKHCERFLKQQQAPVKSSLFCLQGAYAGHDWFVSSLFLM 1123
Cdd:pfam14961 1035 DADVKNASLSSVQQLGVKMTIRYGKYLNLLKEDAENDLCLVLKHCEQFLKQQQVKVSSSLRCLQGGYPGHDWFASSVFLI 1114

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062  1124 LSGDGERTLRFLLRFSRLLASALLWLPRLHLSRYLPADTVASGIHPAYFCSAHCTEMLLKTEVPLVYSAFHMSGFAPSQI 1203
Cdd:pfam14961 1115 MSGDKERSLSFLLRFSHLLVSAFLWPPRLHASIHLPADTAESGIHPVYSCTAHYVEMLLKAEVPLVFSAFRMSGFTPSQI 1194

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062  1204 CLQWITQCFWNYLDWIEICHYIATCVFLGPDYQVYICIAIFKHLQQEILQHTQTQDLQVFLKEEALRGFRVSDHFEYMEM 1283
Cdd:pfam14961 1195 CLQWLTQCFWNYLDWTEICHYIATCIFMGPDYQVYMCISILKHLQQEILQHTQTQDLQVFLKEEPIHGFRVSNYLEYMES 1274

                         1290
                   ....*....|....*...
gi 351701062  1284 LERNYRPALLRDMRAIRE 1301
Cdd:pfam14961 1275 LEQTYRPMVLTDMRNIRV 1292
 
Name Accession Description Interval E-value
BROMI pfam14961
Broad-minded protein; Broad-minded protein (BROMI) interacts with cell cycle-related kinase ...
 12-1301 0e+00

Broad-minded protein; Broad-minded protein (BROMI) interacts with cell cycle-related kinase (CCRK), together these proteins regulate ciliary membrane and axonemal growth.


Pssm-ID: 464406  Cd Length: 1292  Bit Score: 2311.65  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062    12 LRAMLRQLIQSVKERVTGAPSLQCAKEVLLRLEETDANFHNYELVRYLRQHICSTLGPMIEEEMEKCASEKNQGEEPGYD 91
Cdd:pfam14961    1 LQSLLRQLLQSVKEKISGAPSVECAEEILLHLEETDENFHNYEFVKYLRQYIESTLGSVIEEETEKCTSEEGQGEGSGQD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062    92 TVVQCVLARVQESAQYKDMMHSLKGVMTAMVGCMSSGFEEQEeeeeeTQRPERQRKAHREKGSRHCTDSCSDSDSSFSQS 171
Cdd:pfam14961   81 TLVQAVTKRTRESKEYKEMMHSLKNVMMVVVESLINKFEEDQ-----MRKEEMHRKSQHEQLSSHYTDNCSDSDSSFNQS 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   172 YKF-CPGKLQLIVDQLDPRQPKEVRHEALQMLCSAPPSDILGCENGASLCQRLTAALSDPDPVLSDRILKFYAQAFILLP 250
Cdd:pfam14961  156 YTFmSQEQLQLIAEKLDPRQPKEVRWEALQTLCHAPPSDVLSCESWTSLRRNLMAALSDPDPALSDKILRFYAKTFSSSP 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   251 LHMTNEIYTSLAKYLELYFLSRESHIPTLSAGVDVNNPDVTRLLKKVRLLSEYQKEAPSFWIRHPEKYMEEIVESTLSLL 330
Cdd:pfam14961  236 LNITREIYTSLAKHLESYFLSSKLSFPSLSAGLDINNPDVARLLKKIRLLNEFQKEVPSFWIRHPEKYMEEIVESTLSLL 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   331 SAEHAPG--PLLSPKILDPICFFALVDTKAVWFKKWTHAYYSRTTVLKLLEKKYKSLIIAAVQQCIQYLELCETSKADLI 408
Cdd:pfam14961  316 SLHHEQGlnSPGSDKVLDPIYFLALLDIKATWFKKWMHGYYSRTVVLRLLEKKYKSLIVAAVQQCIDYFESCEASVDKTT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   409 ----LGHSKHCGDKQKTlYYSGQEVQYIYFIHSLCLLGRLLIYTQGRKLFPIKLKNRHDSVSLTDLVVLFIRLIYYSPSH 484
Cdd:pfam14961  396 eishSSHQQHIGNKQRT-FYTGKELQYIYFVHSLCLLGRLLIYTQGRKLFPIKLKNRKDPVSLTDLLVLLIRLIYYSPSL 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   485 PDTTPDVDSEDYSPASMVTEILQILCDQKECAMECLYSSTVISTLLQPIHNLMKGNEAAPHCSETALIHAAGVLARIASA 564
Cdd:pfam14961  475 PKETPHVGSDNYSPASLVMEVLQILCDRKECAAECLYQDTVIETLLQPIITLLNGKEAKLNCSETTLIHIADILARIAST 554

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   565 EEGLALLLYGEDMSPSEEDSLTGAHVTAQFTKRLLEGEVPGLAGSALLPAVQRAFVSLCCQMCGTCEGLQALLPYSLHEA 644
Cdd:pfam14961  555 ERGLSLLLYGGNLSSAEEESISAAHVIVQFTKKLLDKEIPVLSGSELLPSLKGAFIFVCRQMYNTCEGLQVLLPYGLHES 634

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   645 VAQARRKASLPSEGIPTPVLGSHSVSSVSQGSQNIMAWEESLLDDLLNFAATPKGLLLLHRAGVINDCVTFMSNQYAENL 724
Cdd:pfam14961  635 IAEAWKKASLLSERVPTPVPGADCSSSVSQESQNVVVWEETLLDNLLNFAATPKGLLLLQQTGAINECVTYMFSRFTKKL 714

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   725 QVSRQKKVGYGVLVTQVASTAAGAAVLRDSGFVSALVAGLWSSLECGGEDTMVNHPRPTPVEPIDRSCQKSFLALVSLLS 804
Cdd:pfam14961  715 QVSRCEKFGYGVMVTQVAATAPGAVALQSSGFVRALVLELWSVLECGRDDVRVTHPKSTPVDPIDRSCQKSFLALVNLLS 794

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   805 S-PAGYELLGLQDLPNRAEYSLHELPTCVTDIIDRLIILNSEAKIHSLFNYEQSHIFGLRLLSVMCCDLDLLLLLEAQYQ 883
Cdd:pfam14961  795 SyPAVYELLGNQELPNKTEYSLREMPTSIIDLIDRLIIINSEAKIHSLFNYEQSHTFGLRLLSVLCCNLDSLLLLESQYN 874

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   884 VSRVLLRAQEENISEVSGSHRGFIIDGLSVERNHVLVRMNLIGGPLERTVPPRTLDKGENPYPWPMFSSYPLPHCYRSKA 963
Cdd:pfam14961  875 ISEVLLQAQKENVTEPSGSEGEFIIDGLSVERNHILVRINLIGGPSERILPPRALQKGEDPYPWPMFSSYPLPKCYLPDV 954

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062   964 TRNPDIKQDADLSQLLSCFMISDKQTEWVENCQRQFCTAMKSKGHVISGGALGELLEKFVLHLTEIPAECYFPSVEYTAA 1043
Cdd:pfam14961  955 PRITDTKQDSELSKFLSSSKNPEKQAEWMENCRRQFCKIMKTKPDTISGGVLAELLEKFVLHLSESPSECYFSSTEYKAA 1034

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062  1044 DADVRSESLSSVQQLGVRMAISYGKFLNLLNDGAESDLALVLKHCERFLKQQQAPVKSSLFCLQGAYAGHDWFVSSLFLM 1123
Cdd:pfam14961 1035 DADVKNASLSSVQQLGVKMTIRYGKYLNLLKEDAENDLCLVLKHCEQFLKQQQVKVSSSLRCLQGGYPGHDWFASSVFLI 1114

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062  1124 LSGDGERTLRFLLRFSRLLASALLWLPRLHLSRYLPADTVASGIHPAYFCSAHCTEMLLKTEVPLVYSAFHMSGFAPSQI 1203
Cdd:pfam14961 1115 MSGDKERSLSFLLRFSHLLVSAFLWPPRLHASIHLPADTAESGIHPVYSCTAHYVEMLLKAEVPLVFSAFRMSGFTPSQI 1194

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351701062  1204 CLQWITQCFWNYLDWIEICHYIATCVFLGPDYQVYICIAIFKHLQQEILQHTQTQDLQVFLKEEALRGFRVSDHFEYMEM 1283
Cdd:pfam14961 1195 CLQWLTQCFWNYLDWTEICHYIATCIFMGPDYQVYMCISILKHLQQEILQHTQTQDLQVFLKEEPIHGFRVSNYLEYMES 1274

                         1290
                   ....*....|....*...
gi 351701062  1284 LERNYRPALLRDMRAIRE 1301
Cdd:pfam14961 1275 LEQTYRPMVLTDMRNIRV 1292
RabGAP-TBC pfam00566
Rab-GTPase-TBC domain; Identification of a TBC domain in GYP6_YEAST and GYP7_YEAST, which are ...
 1181-1252 1.15e-03

Rab-GTPase-TBC domain; Identification of a TBC domain in GYP6_YEAST and GYP7_YEAST, which are GTPase activator proteins of yeast Ypt6 and Ypt7, implies that these domains are GTPase activator proteins of Rab-like small GTPases.


Pssm-ID: 459855  Cd Length: 178  Bit Score: 41.47  E-value: 1.15e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 351701062  1181 LLKTEVPLVYSAFHMSGFAPSQICLQWITQCFWNYLDWIEICHYIATCVFLGPDYQVY-ICIAIFKHLQQEIL 1252
Cdd:pfam00566  106 LLKKKLPKLYKHLKELGLDPDLFASQWFLTLFAREFPLSTVLRIWDYFFLEGEKFVLFrVALAILKRFREELL 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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