NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|328766929|gb|EGF76981|]
View 

hypothetical protein BATDEDRAFT_5722, partial [Batrachochytrium dendrobatidis JAM81]

Protein Classification

mitochondrial fission process 1 family protein( domain architecture ID 10565868)

mitochondrial fission process 1 (MTFP1) family protein such as MTFP1 (also known as MTP18) which is a 18KDa mitochondria-localized protein involved in mitochondrial fission

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
MTP18 pfam10558
Mitochondrial 18 KDa protein (MTP18); This family of proteins are mitochondrial 18KDa proteins ...
10-151 7.60e-70

Mitochondrial 18 KDa protein (MTP18); This family of proteins are mitochondrial 18KDa proteins that are often misannotated as carbonic anhydrases. It was shown that knockdown of MTP18 protein results in a cytochrome c release from mitochondria and consequently leads to apoptosis. Overexpression studies suggest that MTP18 is required for mitochondrial fission.


:

Pssm-ID: 431357  Cd Length: 169  Bit Score: 208.25  E-value: 7.60e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328766929   10 LRILGYAGRLRNFVTAGSRYLAYTSDMGEAFRPVVPRSVVNAAYGVSFAYVGIDVAYEGYKSSLRGDSPM---------- 79
Cdd:pfam10558   1 LRYAAYANRLRTILLSAHRYVAYTSDIGESFRPVAHPYLVRAAYGVSWAYILGDVSYEGYKAYLRNQRPLdpslepwkda 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328766929   80 ----------------EVTRTV-VERTIFQGLASLLLPAITIHSVVDLTTKALKNTSINALKRWGPTAAGLAVLPVLPIL 142
Cdd:pfam10558  81 ppddlaplppskvpllEDYRTVmAKRAVFQSIASMGLPAFTIHSVVRYSGRAFKNVKNPRIRTWGPIGLGLAVVPALPYL 160

                  ....*....
gi 328766929  143 LDRPVEYVM 151
Cdd:pfam10558 161 FDEPVEHAV 169
 
Name Accession Description Interval E-value
MTP18 pfam10558
Mitochondrial 18 KDa protein (MTP18); This family of proteins are mitochondrial 18KDa proteins ...
10-151 7.60e-70

Mitochondrial 18 KDa protein (MTP18); This family of proteins are mitochondrial 18KDa proteins that are often misannotated as carbonic anhydrases. It was shown that knockdown of MTP18 protein results in a cytochrome c release from mitochondria and consequently leads to apoptosis. Overexpression studies suggest that MTP18 is required for mitochondrial fission.


Pssm-ID: 431357  Cd Length: 169  Bit Score: 208.25  E-value: 7.60e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328766929   10 LRILGYAGRLRNFVTAGSRYLAYTSDMGEAFRPVVPRSVVNAAYGVSFAYVGIDVAYEGYKSSLRGDSPM---------- 79
Cdd:pfam10558   1 LRYAAYANRLRTILLSAHRYVAYTSDIGESFRPVAHPYLVRAAYGVSWAYILGDVSYEGYKAYLRNQRPLdpslepwkda 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328766929   80 ----------------EVTRTV-VERTIFQGLASLLLPAITIHSVVDLTTKALKNTSINALKRWGPTAAGLAVLPVLPIL 142
Cdd:pfam10558  81 ppddlaplppskvpllEDYRTVmAKRAVFQSIASMGLPAFTIHSVVRYSGRAFKNVKNPRIRTWGPIGLGLAVVPALPYL 160

                  ....*....
gi 328766929  143 LDRPVEYVM 151
Cdd:pfam10558 161 FDEPVEHAV 169
 
Name Accession Description Interval E-value
MTP18 pfam10558
Mitochondrial 18 KDa protein (MTP18); This family of proteins are mitochondrial 18KDa proteins ...
10-151 7.60e-70

Mitochondrial 18 KDa protein (MTP18); This family of proteins are mitochondrial 18KDa proteins that are often misannotated as carbonic anhydrases. It was shown that knockdown of MTP18 protein results in a cytochrome c release from mitochondria and consequently leads to apoptosis. Overexpression studies suggest that MTP18 is required for mitochondrial fission.


Pssm-ID: 431357  Cd Length: 169  Bit Score: 208.25  E-value: 7.60e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328766929   10 LRILGYAGRLRNFVTAGSRYLAYTSDMGEAFRPVVPRSVVNAAYGVSFAYVGIDVAYEGYKSSLRGDSPM---------- 79
Cdd:pfam10558   1 LRYAAYANRLRTILLSAHRYVAYTSDIGESFRPVAHPYLVRAAYGVSWAYILGDVSYEGYKAYLRNQRPLdpslepwkda 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328766929   80 ----------------EVTRTV-VERTIFQGLASLLLPAITIHSVVDLTTKALKNTSINALKRWGPTAAGLAVLPVLPIL 142
Cdd:pfam10558  81 ppddlaplppskvpllEDYRTVmAKRAVFQSIASMGLPAFTIHSVVRYSGRAFKNVKNPRIRTWGPIGLGLAVVPALPYL 160

                  ....*....
gi 328766929  143 LDRPVEYVM 151
Cdd:pfam10558 161 FDEPVEHAV 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH