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Conserved domains on  [gi|240279359|gb|EER42864|]
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M protein repeat protein [Histoplasma capsulatum H143]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TMF_TATA_bd pfam12325
TATA element modulatory factor 1 TATA binding; This is the C-terminal conserved coiled coil ...
 746-860 7.42e-46

TATA element modulatory factor 1 TATA binding; This is the C-terminal conserved coiled coil region of a family of TATA element modulatory factor 1 proteins conserved in eukaryotes. The proteins bind to the TATA element of some RNA polymerase II promoters and repress their activity. by competing with the binding of TATA binding protein. TMF1_TATA_bd is the most conserved part of the TMFs. TMFs are evolutionarily conserved golgins that bind Rab6, a ubiquitous ras-like GTP-binding Golgi protein, and contribute to Golgi organization in animal and plant cells. The Rab6-binding domain appears to be the same region as this C-terminal family.


:

Pssm-ID: 432481 [Multi-domain]  Cd Length: 115  Bit Score: 159.63  E-value: 7.42e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  746 SVSTVAAGPSVQVVERMSTTIRRLESERAAFKDEIVRLTAQRDEARQEVVELMREVEEKRKCDQRIQELEATVEQLDQRY 825
Cdd:pfam12325   1 SVSTSGAGPSVQLVERLSSTIRRLEGELASLKEELARLEAQRDEARQEIVKLMKENEELKELKKELEELEKELKELEQRY 80

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 240279359  826 QTTLEMLGEKSELVEELKADISDLKKIYRELVDST 860
Cdd:pfam12325  81 ETTLELLGEKSEEVEELKADVEDLKEMYREQVQQL 115
TMF_DNA_bd pfam12329
TATA element modulatory factor 1 DNA binding; This is the middle region of a family of TATA ...
 271-344 8.53e-21

TATA element modulatory factor 1 DNA binding; This is the middle region of a family of TATA element modulatory factor 1 proteins conserved in eukaryotes that contains at its N-terminal section a number of leucine zippers that could potentially form coiled coil structures.. The whole proteins bind to the TATA element of some RNA polymerase II promoters and repress their activity. by competing with the binding of TATA binding protein. TMFs are evolutionarily conserved golgins that bind Rab6, a ubiquitous ras-like GTP-binding Golgi protein, and contribute to Golgi organization in animal and plant cells.


:

Pssm-ID: 372049 [Multi-domain]  Cd Length: 74  Bit Score: 86.98  E-value: 8.53e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 240279359  271 GSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAE 344
Cdd:pfam12329   1 SSLEKLLKEKDEQIAQLMEEGEKLSKKELKLNNTIKKLRAKNKELEKEIAELKKKLEKLEKELENLEERLKRAE 74
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 302-616 2.67e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 2.67e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   302 RATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAeiaeQKALERLN-SVSKAEKQLETATAEREASNATITD 380
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQL----RKELEELSrQISALRKDLARLEAEVEQLEERIAQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   381 LKSQLARA-VSRAEAAERKARMEATEAE-KRQIAELRDDLSSAKIEREISEE---KLRREIRDLKEGIEREKERARIREI 455
Cdd:TIGR02168  752 LSKELTELeAEIEELEERLEEAEEELAEaEAEIEELEAQIEQLKEELKALREaldELRAELTLLNEEAANLRERLESLER 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   456 ELRGEQSVLESKMESLRSRAEEVSSSAtgESHAKLLRQIEVLQTQYAVASEnwhgiegsliaRLTAVETERDELERREGD 535
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLA--AEIEELEELIEELESELEALLN-----------ERASLEEALALLRSELEE 898

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   536 LRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLvvkQDLAKQKEAELTLIQRLEEERA 615
Cdd:TIGR02168  899 LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL---EEAEALENKIEDDEEEARRRLK 975


                   .
gi 240279359   616 R 616
Cdd:TIGR02168  976 R 976
 
Name Accession Description Interval E-value
TMF_TATA_bd pfam12325
TATA element modulatory factor 1 TATA binding; This is the C-terminal conserved coiled coil ...
 746-860 7.42e-46

TATA element modulatory factor 1 TATA binding; This is the C-terminal conserved coiled coil region of a family of TATA element modulatory factor 1 proteins conserved in eukaryotes. The proteins bind to the TATA element of some RNA polymerase II promoters and repress their activity. by competing with the binding of TATA binding protein. TMF1_TATA_bd is the most conserved part of the TMFs. TMFs are evolutionarily conserved golgins that bind Rab6, a ubiquitous ras-like GTP-binding Golgi protein, and contribute to Golgi organization in animal and plant cells. The Rab6-binding domain appears to be the same region as this C-terminal family.


Pssm-ID: 432481 [Multi-domain]  Cd Length: 115  Bit Score: 159.63  E-value: 7.42e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  746 SVSTVAAGPSVQVVERMSTTIRRLESERAAFKDEIVRLTAQRDEARQEVVELMREVEEKRKCDQRIQELEATVEQLDQRY 825
Cdd:pfam12325   1 SVSTSGAGPSVQLVERLSSTIRRLEGELASLKEELARLEAQRDEARQEIVKLMKENEELKELKKELEELEKELKELEQRY 80

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 240279359  826 QTTLEMLGEKSELVEELKADISDLKKIYRELVDST 860
Cdd:pfam12325  81 ETTLELLGEKSEEVEELKADVEDLKEMYREQVQQL 115
TMF_DNA_bd pfam12329
TATA element modulatory factor 1 DNA binding; This is the middle region of a family of TATA ...
 271-344 8.53e-21

TATA element modulatory factor 1 DNA binding; This is the middle region of a family of TATA element modulatory factor 1 proteins conserved in eukaryotes that contains at its N-terminal section a number of leucine zippers that could potentially form coiled coil structures.. The whole proteins bind to the TATA element of some RNA polymerase II promoters and repress their activity. by competing with the binding of TATA binding protein. TMFs are evolutionarily conserved golgins that bind Rab6, a ubiquitous ras-like GTP-binding Golgi protein, and contribute to Golgi organization in animal and plant cells.


Pssm-ID: 372049 [Multi-domain]  Cd Length: 74  Bit Score: 86.98  E-value: 8.53e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 240279359  271 GSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAE 344
Cdd:pfam12329   1 SSLEKLLKEKDEQIAQLMEEGEKLSKKELKLNNTIKKLRAKNKELEKEIAELKKKLEKLEKELENLEERLKRAE 74
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 302-616 2.67e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 2.67e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   302 RATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAeiaeQKALERLN-SVSKAEKQLETATAEREASNATITD 380
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQL----RKELEELSrQISALRKDLARLEAEVEQLEERIAQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   381 LKSQLARA-VSRAEAAERKARMEATEAE-KRQIAELRDDLSSAKIEREISEE---KLRREIRDLKEGIEREKERARIREI 455
Cdd:TIGR02168  752 LSKELTELeAEIEELEERLEEAEEELAEaEAEIEELEAQIEQLKEELKALREaldELRAELTLLNEEAANLRERLESLER 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   456 ELRGEQSVLESKMESLRSRAEEVSSSAtgESHAKLLRQIEVLQTQYAVASEnwhgiegsliaRLTAVETERDELERREGD 535
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLA--AEIEELEELIEELESELEALLN-----------ERASLEEALALLRSELEE 898

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   536 LRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLvvkQDLAKQKEAELTLIQRLEEERA 615
Cdd:TIGR02168  899 LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL---EEAEALENKIEDDEEEARRRLK 975


                   .
gi 240279359   616 R 616
Cdd:TIGR02168  976 R 976
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 321-616 1.43e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.52  E-value: 1.43e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 321 ETKKRLEKVEKDLVNAEDRVS-----------QAEIAEQ-----------KALERLNSVSKAEKQLETATAEREASNATI 378
Cdd:COG1196  176 EAERKLEATEENLERLEDILGelerqleplerQAEKAERyrelkeelkelEAELLLLKLRELEAELEELEAELEELEAEL 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 379 TDLKSQLARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRReiRDLKEGIEREKERARIREIELR 458
Cdd:COG1196  256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR--RELEERLEELEEELAELEEELE 333

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 459 GEQSVLESKMESLRSRAEEVSSSAtgESHAKLLRQIEVLQTQYAVASENWHGIEGSLIARLTAVETERDELERREGDLRR 538
Cdd:COG1196  334 ELEEELEELEEELEEAEEELEEAE--AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEA 411

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 240279359 539 KAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERAR 616
Cdd:COG1196  412 LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
PTZ00121 PTZ00121
MAEBL; Provisional
 240-631 2.37e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.86  E-value: 2.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  240 VERIDALQSKLKYLAKEAAESAKNAAASAEAGSLEKKLLE--KDEQIANLMEEGQKLSktELDHRATIKKLrqsiAESAK 317
Cdd:PTZ00121 1390 KKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEkkKADEAKKKAEEAKKAD--EAKKKAEEAKK----AEEAK 1463

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  318 SQAETKKRLEKVEKdlvNAEDRvSQAEIAEQKALERLNSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAER 397
Cdd:PTZ00121 1464 KKAEEAKKADEAKK---KAEEA-KKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEA 1539

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  398 KARMEATEAEK-RQIAELRDDLSSAKIEREISEEKlRREIRDLKEGIEREKERARIREIELRGEQSVLES-----KMESL 471
Cdd:PTZ00121 1540 KKAEEKKKADElKKAEELKKAEEKKKAEEAKKAEE-DKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKaeeakKAEEA 1618

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  472 RSRAEEVSSSATGESHAKLLRQI---EVLQTQYAVASENWHGIEGSLIARLTAVETERDELERREGDLRRKAREASLKAK 548
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKeaeEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA 1698

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  549 KVEGELENSRAVIQEIERNLEASK--QEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERARWQELARRPSS 626
Cdd:PTZ00121 1699 EEAKKAEELKKKEAEEKKKAEELKkaEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778


                  ....*
gi 240279359  627 PFLQE 631
Cdd:PTZ00121 1779 AVIEE 1783
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 274-619 2.73e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 54.41  E-value: 2.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   274 EKKLLEK--DEQIANLMEEGQK---LSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVS--QAEIA 346
Cdd:pfam01576  153 ERKLLEEriSEFTSNLAEEEEKaksLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAelQAQIA 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   347 EQKAlerlnSVSKAEKQLETA-------TAEREASNATITDLKSQLARAVSRAEaAERKARMEAtEAEKRQIA------- 412
Cdd:pfam01576  233 ELRA-----QLAKKEEELQAAlarleeeTAQKNNALKKIRELEAQISELQEDLE-SERAARNKA-EKQRRDLGeelealk 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   413 -ELRDDLSSAKIEREIsEEKLRREIRDLKEGIEREKERARIREIELRGEQSvleSKMESLRSRAEEVSSSATGESHAKLL 491
Cdd:pfam01576  306 tELEDTLDTTAAQQEL-RSKREQEVTELKKALEEETRSHEAQLQEMRQKHT---QALEELTEQLEQAKRNKANLEKAKQA 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   492 RQIEVLQTQYAVASENWHGIEGSliARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEAS 571
Cdd:pfam01576  382 LESENAELQAELRTLQQAKQDSE--HKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKL 459

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 240279359   572 KQEIQNLTRKLTKAENdflvVKQDLAKQKEAELTLIQRLEEERARWQE 619
Cdd:pfam01576  460 SKDVSSLESQLQDTQE----LLQEETRQKLNLSTRLRQLEDERNSLQE 503
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 275-650 6.44e-06

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 50.01  E-value: 6.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 275 KKLLEKDEQIANLmEEGQKLS--KTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEiaeqkale 352
Cdd:NF033838  75 QKSLDKRKHTQNV-ALNKKLSdiKTEYLYELNVLKEKSEAELTSKTKKELDAAFEQFKKDTLEPGKKVAEAT-------- 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 353 rlNSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEKRQiAELRDDLSSAKIEREISEEKL 432
Cdd:NF033838 146 --KKVEEAEKKAKDQKEEDRRNYPTNTYKTLELEIAESDVEVKKAELELVKEEAKEPR-DEEKIKQAKAKVESKKAEATR 222

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 433 RREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEvssSATGESHAKLLRQIEVLQTQYAVASENWHGIE 512
Cdd:NF033838 223 LEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKR---GVLGEPATPDKKENDAKSSDSSVGEETLPSPS 299

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 513 GSLIARLTAVETERDELERREGDLRRKARE--ASLKAKKVEGELENSRAVIQEIErnLEASKQEiqnltrklTKAENDFL 590
Cdd:NF033838 300 LKPEKKVAEAEKKVEEAKKKAKDQKEEDRRnyPTNTYKTLELEIAESDVKVKEAE--LELVKEE--------AKEPRNEE 369

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 240279359 591 VVKQDLAK--QKEAELTLIQRLEEERARWQELARRPSSPF--LQEPPTGSPITFNRKQTAGPDP 650
Cdd:NF033838 370 KIKQAKAKveSKKAEATRLEKIKTDRKKAEEEAKRKAAEEdkVKEKPAEQPQPAPAPQPEKPAP 433
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 271-409 6.91e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.30  E-value: 6.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 271 GSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKV---------EKDLVNAEDRVS 341
Cdd:COG1579   27 KELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVrnnkeyealQKEIESLKRRIS 106

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 240279359 342 QAEIAEQKALERLnsvSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEKR 409
Cdd:COG1579  107 DLEDEILELMERI---EELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
PilO COG3167
Type IV pilus assembly protein PilO [Cell motility, Extracellular structures];
785-849 7.74e-05

Type IV pilus assembly protein PilO [Cell motility, Extracellular structures];


Pssm-ID: 442400 [Multi-domain]  Cd Length: 202  Bit Score: 44.55  E-value: 7.74e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240279359 785 AQRDEARQEVVELMREVEEKRKCDQRIQELEATVEQLDQRYQTTLEMLGEKSElVEELKADISDL 849
Cdd:COG3167   46 EELEELEAEEAQLKQELEKKQAKAANLPALKAQLEELEQQLGELLKQLPSKAE-VPALLDDISQA 109
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 291-399 2.46e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 41.74  E-value: 2.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  291 GQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLvnaEDRVSQAEIAEQKALERLNSVSKAEKQLETAT-- 368
Cdd:NF012221 1670 GKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQDI---DDAKADAEKRKDDALAKQNEAQQAESDANAAAnd 1746

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 240279359  369 ----AEREASNAtitdlKSQLARAVSRAEAAERKA 399
Cdd:NF012221 1747 aqsrGEQDASAA-----ENKANQAQADAKGAKQDE 1776
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 273-542 5.30e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 40.38  E-value: 5.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 273 LEKKLLEKDEQIANL---MEEGQKLSK--TELDHR----ATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQA 343
Cdd:NF033838 130 FKKDTLEPGKKVAEAtkkVEEAEKKAKdqKEEDRRnyptNTYKTLELEIAESDVEVKKAELELVKEEAKEPRDEEKIKQA 209

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 344 EI---AEQKALERLNSVSKAEKQletatAEREASNATITDLKSQLARAVSRAEAAERKARME-------ATEAEKRQIAE 413
Cdd:NF033838 210 KAkveSKKAEATRLEKIKTDREK-----AEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKrgvlgepATPDKKENDAK 284

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 414 LRDDL--------SSAKIEREISE-----EKLRREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEVSS 480
Cdd:NF033838 285 SSDSSvgeetlpsPSLKPEKKVAEaekkvEEAKKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELELVKEEAKE 364

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240279359 481 SATGEshakllrqiEVLQTQYAVASENwhgiegsliARLTAVETERDELERREGDLRRKARE 542
Cdd:NF033838 365 PRNEE---------KIKQAKAKVESKK---------AEATRLEKIKTDRKKAEEEAKRKAAE 408
ATP-synt_Fo_b cd06503
F-type ATP synthase, membrane subunit b; Membrane subunit b is a component of the Fo complex ...
 323-439 5.82e-03

F-type ATP synthase, membrane subunit b; Membrane subunit b is a component of the Fo complex of FoF1-ATP synthase. The F-type ATP synthases (FoF1-ATPase) consist of two structural domains: the F1 (assembly factor one) complex containing the soluble catalytic core, and the Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F1 is composed of alpha (or A), beta (B), gamma (C), delta (D) and epsilon (E) subunits with a stoichiometry of 3:3:1:1:1, while Fo consists of the three subunits a, b, and c (1:2:10-14). An oligomeric ring of 10-14 c subunits (c-ring) make up the Fo rotor. The flux of protons through the ATPase channel (Fo) drives the rotation of the c-ring, which in turn is coupled to the rotation of the F1 complex gamma subunit rotor due to the permanent binding between the gamma and epsilon subunits of F1 and the c-ring of Fo. The F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. The F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis. This group also includes F-ATP synthase that has also been found in the archaea Candidatus Methanoperedens.


Pssm-ID: 349951 [Multi-domain]  Cd Length: 132  Bit Score: 37.80  E-value: 5.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 323 KKRLEKVEKDLVNAEDRVSQAEIAEQkalerlnsvsKAEKQLETATAEREAsnatitdlksQLARAVSRAEAAERKARME 402
Cdd:cd06503   29 DEREEKIAESLEEAEKAKEEAEELLA----------EYEEKLAEARAEAQE----------IIEEARKEAEKIKEEILAE 88

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 240279359 403 ATEAEKRQIAELRDDLSSakiEREISEEKLRREIRDL 439
Cdd:cd06503   89 AKEEAERILEQAKAEIEQ---EKEKALAELRKEVADL 122
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
766-856 8.70e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 39.66  E-value: 8.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 766 IRRLESERAAFKDEIVRLTAQRDEARQEVVELMREVEEKRKCDQRIQELEATVEQLDQRYQTTLEMLGEKSELVEELKAD 845
Cdd:PRK03918 195 IKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKE 274

                         90
                 ....*....|.
gi 240279359 846 ISDLKKIYREL 856
Cdd:PRK03918 275 IEELEEKVKEL 285
 
Name Accession Description Interval E-value
TMF_TATA_bd pfam12325
TATA element modulatory factor 1 TATA binding; This is the C-terminal conserved coiled coil ...
 746-860 7.42e-46

TATA element modulatory factor 1 TATA binding; This is the C-terminal conserved coiled coil region of a family of TATA element modulatory factor 1 proteins conserved in eukaryotes. The proteins bind to the TATA element of some RNA polymerase II promoters and repress their activity. by competing with the binding of TATA binding protein. TMF1_TATA_bd is the most conserved part of the TMFs. TMFs are evolutionarily conserved golgins that bind Rab6, a ubiquitous ras-like GTP-binding Golgi protein, and contribute to Golgi organization in animal and plant cells. The Rab6-binding domain appears to be the same region as this C-terminal family.


Pssm-ID: 432481 [Multi-domain]  Cd Length: 115  Bit Score: 159.63  E-value: 7.42e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  746 SVSTVAAGPSVQVVERMSTTIRRLESERAAFKDEIVRLTAQRDEARQEVVELMREVEEKRKCDQRIQELEATVEQLDQRY 825
Cdd:pfam12325   1 SVSTSGAGPSVQLVERLSSTIRRLEGELASLKEELARLEAQRDEARQEIVKLMKENEELKELKKELEELEKELKELEQRY 80

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 240279359  826 QTTLEMLGEKSELVEELKADISDLKKIYRELVDST 860
Cdd:pfam12325  81 ETTLELLGEKSEEVEELKADVEDLKEMYREQVQQL 115
TMF_DNA_bd pfam12329
TATA element modulatory factor 1 DNA binding; This is the middle region of a family of TATA ...
 271-344 8.53e-21

TATA element modulatory factor 1 DNA binding; This is the middle region of a family of TATA element modulatory factor 1 proteins conserved in eukaryotes that contains at its N-terminal section a number of leucine zippers that could potentially form coiled coil structures.. The whole proteins bind to the TATA element of some RNA polymerase II promoters and repress their activity. by competing with the binding of TATA binding protein. TMFs are evolutionarily conserved golgins that bind Rab6, a ubiquitous ras-like GTP-binding Golgi protein, and contribute to Golgi organization in animal and plant cells.


Pssm-ID: 372049 [Multi-domain]  Cd Length: 74  Bit Score: 86.98  E-value: 8.53e-21
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 240279359  271 GSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAE 344
Cdd:pfam12329   1 SSLEKLLKEKDEQIAQLMEEGEKLSKKELKLNNTIKKLRAKNKELEKEIAELKKKLEKLEKELENLEERLKRAE 74
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 302-616 2.67e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 2.67e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   302 RATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAeiaeQKALERLN-SVSKAEKQLETATAEREASNATITD 380
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQL----RKELEELSrQISALRKDLARLEAEVEQLEERIAQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   381 LKSQLARA-VSRAEAAERKARMEATEAE-KRQIAELRDDLSSAKIEREISEE---KLRREIRDLKEGIEREKERARIREI 455
Cdd:TIGR02168  752 LSKELTELeAEIEELEERLEEAEEELAEaEAEIEELEAQIEQLKEELKALREaldELRAELTLLNEEAANLRERLESLER 831

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   456 ELRGEQSVLESKMESLRSRAEEVSSSAtgESHAKLLRQIEVLQTQYAVASEnwhgiegsliaRLTAVETERDELERREGD 535
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIESLA--AEIEELEELIEELESELEALLN-----------ERASLEEALALLRSELEE 898

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   536 LRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLvvkQDLAKQKEAELTLIQRLEEERA 615
Cdd:TIGR02168  899 LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL---EEAEALENKIEDDEEEARRRLK 975


                   .
gi 240279359   616 R 616
Cdd:TIGR02168  976 R 976
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 321-616 1.43e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 81.52  E-value: 1.43e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 321 ETKKRLEKVEKDLVNAEDRVS-----------QAEIAEQ-----------KALERLNSVSKAEKQLETATAEREASNATI 378
Cdd:COG1196  176 EAERKLEATEENLERLEDILGelerqleplerQAEKAERyrelkeelkelEAELLLLKLRELEAELEELEAELEELEAEL 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 379 TDLKSQLARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRReiRDLKEGIEREKERARIREIELR 458
Cdd:COG1196  256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR--RELEERLEELEEELAELEEELE 333

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 459 GEQSVLESKMESLRSRAEEVSSSAtgESHAKLLRQIEVLQTQYAVASENWHGIEGSLIARLTAVETERDELERREGDLRR 538
Cdd:COG1196  334 ELEEELEELEEELEEAEEELEEAE--AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEA 411

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 240279359 539 KAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERAR 616
Cdd:COG1196  412 LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA 489
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 219-633 1.22e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 1.22e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 219 AQMRADHEMSELRWQEELHAYVERIDALQSKLK-YLAKEAAESAKNAAASAEAGSLEKKLLEKDEQIANLMEEGQKLSKT 297
Cdd:COG1196  308 EERRRELEERLEELEEELAELEEELEELEEELEeLEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 298 ELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLETATAEREASNAT 377
Cdd:COG1196  388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 378 ITDLKSQLARAVSRAEAAERKAR---------MEATEAEKRQIAELRDDLSSAKIEREISEE------------------ 430
Cdd:COG1196  468 LLEEAALLEAALAELLEELAEAAarllllleaEADYEGFLEGVKAALLLAGLRGLAGAVAVLigveaayeaaleaalaaa 547

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 431 ---KLRREIRDLKEGIEREKERA-------RIREIELRGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQ 500
Cdd:COG1196  548 lqnIVVEDDEVAAAAIEYLKAAKagratflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 501 YAVASENWHGIEGSLIARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTR 580
Cdd:COG1196  628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|...
gi 240279359 581 KLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERARWQELARRPSSPFLQEPP 633
Cdd:COG1196  708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 321-623 1.35e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 1.35e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   321 ETKKRLEKVEKDLVNAEDRVSQAEiaeqKALERLnsvskaEKQLETATAEREasnatITDLKSQLARAVSRAEAAERKAR 400
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELE----RQLKSL------ERQAEKAERYKE-----LKAELRELELALLVLRLEELREE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   401 MEATEAEKRQIAELRDDLSSAKIEREISEEKLRREIRDLkegiEREKERARIREIELRGEQSVLESKMESLRSRAEEVSS 480
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL----EEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   481 S--ATGESHAKLLRQIEVLQTQYAVASENWHGIEG---SLIARLTAVETERDELERREGDL-------RRKAREASLKAK 548
Cdd:TIGR02168  317 QleELEAQLEELESKLDELAEELAELEEKLEELKEeleSLEAELEELEAELEELESRLEELeeqletlRSKVAQLELQIA 396

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240279359   549 KVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTkaENDFLVVKQDLAKQKEAELTLIQRLEEERARWQELARR 623
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERLEEALEELREE 469
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 302-586 1.84e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.72  E-value: 1.84e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   302 RATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAED-RVSQAEIAEQKALERLNSVSKAEKQLETATAEREASNATITD 380
Cdd:TIGR02169  176 LEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   381 LKSQLARAVSRAEAAER--------------------KARMEATEAE----KRQIAELRDDLSSAKIEREISEEKLRREI 436
Cdd:TIGR02169  256 LTEEISELEKRLEEIEQlleelnkkikdlgeeeqlrvKEKIGELEAEiaslERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   437 RDlKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEVSSSA--TGESHAKLLRQIEVLQTQYAVASENWHGIEGS 514
Cdd:TIGR02169  336 AE-IEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaeTRDELKDYREKLEKLKREINELKRELDRLQEE 414

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240279359   515 LIARLTAVETERDELERREGD---LRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAE 586
Cdd:TIGR02169  415 LQRLSEELADLNAAIAGIEAKineLEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 276-624 3.82e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.43  E-value: 3.82e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 276 KLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLN 355
Cdd:COG1196  233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 356 SVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEKRQIAELRD-----DLSSAKIEREISEE 430
Cdd:COG1196  313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAElaeaeEELEELAEELLEAL 392

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 431 KLRREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEVSSSATGESHA---------KLLRQIEVLQTQY 501
Cdd:COG1196  393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEeaeleeeeeALLELLAELLEEA 472

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 502 AVASENWHGIEGSLIARLTAVETERDELERREGDLR-RKAREASLKAKKVEGELENSRAVIQEIERNLEASkqEIQNLTR 580
Cdd:COG1196  473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA--LAAALQN 550

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 240279359 581 KLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERARWQELARRP 624
Cdd:COG1196  551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALAR 594
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 346-623 5.83e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 5.83e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   346 AEQKALERLNSVSKAEKQLETATAEREASNATITDLKSQLaravSRAEAAERKARMEATEAEkRQIAELRDDLSSAKIER 425
Cdd:TIGR02168  668 TNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL----EELEEELEQLRKELEELS-RQISALRKDLARLEAEV 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   426 EISEEKLRREIRDLKEGIEREKERARIREiELRGEQSVLESKMESLRSRAEEVSssatgESHAKLLRQIEVLQTQYAVAS 505
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIEELEERLE-EAEEELAEAEAEIEELEAQIEQLK-----EELKALREALDELRAELTLLN 816

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   506 ENWHgiegSLIARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEI---------- 575
Cdd:TIGR02168  817 EEAA----NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERasleealall 892

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 240279359   576 ----QNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERARWQELARR 623
Cdd:TIGR02168  893 rselEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 215-614 1.02e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.81  E-value: 1.02e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 215 EEAMAQMRADHEMSELRwQEELHAYVERIDALQSKLKYLAKEAAESAKNAAASAEAGSLEKKLLEKDEQIANLMEEGQKL 294
Cdd:COG1196  383 ELAEELLEALRAAAELA-AQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 295 SKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNS---------VSKAEKQLE 365
Cdd:COG1196  462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgavavligvEAAYEAALE 541

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 366 TATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEKRQIA------------------ELRDDLSSAKIEREI 427
Cdd:COG1196  542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALaaalargaigaavdlvasDLREADARYYVLGDT 621

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 428 SEEKLRREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAVASEN 507
Cdd:COG1196  622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 508 WHGIEGSLIARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKL----- 582
Cdd:COG1196  702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIealgp 781

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....
gi 240279359 583 -----------TKAENDFLVV-KQDLAKQKEAELTLIQRLEEER 614
Cdd:COG1196  782 vnllaieeyeeLEERYDFLSEqREDLEEARETLEEAIEEIDRET 825
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 215-623 1.72e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 1.72e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 215 EEAMAQMRADHEMSELRWQEELHA-YVERIDALQSKLKYLAKEAAESAKNAAASAEAGSLEKKLLEKDEQIANLMEEGQK 293
Cdd:COG1196  360 LAEAEEALLEAEAELAEAEEELEElAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 294 LSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAE------IAEQKALERLNSVSKAEKQLETA 367
Cdd:COG1196  440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAarllllLEAEADYEGFLEGVKAALLLAGL 519

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 368 TAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRREIRDLKEGIEREK 447
Cdd:COG1196  520 RGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 448 ERARIREiELRGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAVASENWHGIEGSLIARLTAVETERD 527
Cdd:COG1196  600 AVDLVAS-DLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 528 ELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQN-LTRKLTKAENDFLVVKQDLAKQKEAELTL 606
Cdd:COG1196  679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEqLEAEREELLEELLEEEELLEEEALEELPE 758

                        410
                 ....*....|....*..
gi 240279359 607 IQRLEEERARWQELARR 623
Cdd:COG1196  759 PPDLEELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 215-623 2.18e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 2.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 215 EEAMAQMRADHEMSELRW---QEELHAYVERIDALQSKLKYLA-KEAAESAKNAAASAEAGSLEKKLLEKDEQIANLMEE 290
Cdd:COG1196  266 EAELEELRLELEELELELeeaQAEEYELLAELARLEQDIARLEeRRRELEERLEELEEELAELEEELEELEEELEELEEE 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 291 GQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLETATAE 370
Cdd:COG1196  346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 371 REASNATITDLKSQLARAVSRAEAAERKARMEATEAEKRQIAELR--------DDLSSAKIEREISEEKLRREIRDLKEG 442
Cdd:COG1196  426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEeaalleaaLAELLEELAEAAARLLLLLEAEADYEG 505

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 443 IER-------------------------EKERARIREIELRGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVL 497
Cdd:COG1196  506 FLEgvkaalllaglrglagavavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRAR 585

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 498 QTQYAVASENWHGIEGSLIARLTAVETER-----DELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASK 572
Cdd:COG1196  586 AALAAALARGAIGAAVDLVASDLREADARyyvlgDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|.
gi 240279359 573 QEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERARWQELARR 623
Cdd:COG1196  666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716
PTZ00121 PTZ00121
MAEBL; Provisional
 240-631 2.37e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.86  E-value: 2.37e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  240 VERIDALQSKLKYLAKEAAESAKNAAASAEAGSLEKKLLE--KDEQIANLMEEGQKLSktELDHRATIKKLrqsiAESAK 317
Cdd:PTZ00121 1390 KKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEkkKADEAKKKAEEAKKAD--EAKKKAEEAKK----AEEAK 1463

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  318 SQAETKKRLEKVEKdlvNAEDRvSQAEIAEQKALERLNSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAER 397
Cdd:PTZ00121 1464 KKAEEAKKADEAKK---KAEEA-KKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEA 1539

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  398 KARMEATEAEK-RQIAELRDDLSSAKIEREISEEKlRREIRDLKEGIEREKERARIREIELRGEQSVLES-----KMESL 471
Cdd:PTZ00121 1540 KKAEEKKKADElKKAEELKKAEEKKKAEEAKKAEE-DKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKaeeakKAEEA 1618

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  472 RSRAEEVSSSATGESHAKLLRQI---EVLQTQYAVASENWHGIEGSLIARLTAVETERDELERREGDLRRKAREASLKAK 548
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKeaeEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEA 1698

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  549 KVEGELENSRAVIQEIERNLEASK--QEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERARWQELARRPSS 626
Cdd:PTZ00121 1699 EEAKKAEELKKKEAEEKKKAEELKkaEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778


                  ....*
gi 240279359  627 PFLQE 631
Cdd:PTZ00121 1779 AVIEE 1783
PTZ00121 PTZ00121
MAEBL; Provisional
 215-623 5.90e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 63.62  E-value: 5.90e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  215 EEAMAQMRADHEMSELRWQEELHAYVERIDALQSKLKYLAKEAAESAKNAAASAEAGSLEKKLLEKDEQIANLMEEGQKL 294
Cdd:PTZ00121 1299 EEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  295 SKTELDHRATIKK----LRQSIAESAKSQAETKKRLEKVEK--DLVNAEDRVSQAEIAEQKALERLNS---VSKAEKQLE 365
Cdd:PTZ00121 1379 KADAAKKKAEEKKkadeAKKKAEEDKKKADELKKAAAAKKKadEAKKKAEEKKKADEAKKKAEEAKKAdeaKKKAEEAKK 1458

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  366 TATAEREASNATITDLKSQLARAVSRAEAAERKA---RMEATEAEKRQIAELRDDLSSAKIEREISEEKLRREIRDLKEG 442
Cdd:PTZ00121 1459 AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAeeaKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE 1538

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  443 IEREKERARIREIELRGEQSVLESKMESLRSRAEEvSSSATGESHAKLLRQIEVlqtqyavasenwhgiegsliARLTAV 522
Cdd:PTZ00121 1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAE-EDKNMALRKAEEAKKAEE--------------------ARIEEV 1597

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  523 ETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQeiqnlTRKLTKAENDFLVVKQDLAKQKEA 602
Cdd:PTZ00121 1598 MKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKK-----AEELKKAEEENKIKAAEEAKKAEE 1672

                         410       420
                  ....*....|....*....|....*
gi 240279359  603 ELTLIQRL----EEERARWQELARR 623
Cdd:PTZ00121 1673 DKKKAEEAkkaeEDEKKAAEALKKE 1697
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
308-501 7.31e-10

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 62.73  E-value: 7.31e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 308 LRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQ-------AEIAEQKALErLNSVSKAEKQLETATAEREASNATITD 380
Cdd:COG3206  166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEfrqknglVDLSEEAKLL-LQQLSELESQLAEARAELAEAEARLAA 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 381 LKSQLARAVSRAEAAERKARMEATEAE----KRQIAELRDDLS-------SAKIEREISEEKLRREIRDLKEGIEREKER 449
Cdd:COG3206  245 LRAQLGSGPDALPELLQSPVIQQLRAQlaelEAELAELSARYTpnhpdviALRAQIAALRAQLQQEAQRILASLEAELEA 324

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 240279359 450 ARIREIELRGEQSVLESKMESLRSRAEEVsssatgeshAKLLRQIEVLQTQY 501
Cdd:COG3206  325 LQAREASLQAQLAQLEARLAELPELEAEL---------RRLEREVEVARELY 367
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
241-623 1.81e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 61.62  E-value: 1.81e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 241 ERIDALQSKLKYLAKEAAESAKNAAASAEAGSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQA 320
Cdd:PRK03918 259 EKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEE 338

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 321 ---ETKKRLEKVEKDLVNAEDRVSQAEIAEQKaLERLNSVSK----------------AEKQLETATAEREASNATITDL 381
Cdd:PRK03918 339 rleELKKKLKELEKRLEELEERHELYEEAKAK-KEELERLKKrltgltpeklekeleeLEKAKEEIEEEISKITARIGEL 417

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 382 KS---QLARAVSRAEAAERKA---RMEATEAEKRQI-----AELRDdLSSAKIEREISEEKLRREIRDLKegIEREKERA 450
Cdd:PRK03918 418 KKeikELKKAIEELKKAKGKCpvcGRELTEEHRKELleeytAELKR-IEKELKEIEEKERKLRKELRELE--KVLKKESE 494

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 451 RIREIELRGEQSVLESKMESLRsrAEEVSSSAtgESHAKLLRQIEVLQTQYAVASENWHGIEGsLIARLTAVETERDELE 530
Cdd:PRK03918 495 LIKLKELAEQLKELEEKLKKYN--LEELEKKA--EEYEKLKEKLIKLKGEIKSLKKELEKLEE-LKKKLAELEKKLDELE 569

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 531 RREGDLRRKAREASLKA-KKVEGELENSRAVIQEIERnLEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKeaeltliQR 609
Cdd:PRK03918 570 EELAELLKELEELGFESvEELEERLKELEPFYNEYLE-LKDAEKELEREEKELKKLEEELDKAFEELAETE-------KR 641

                        410
                 ....*....|....
gi 240279359 610 LEEERARWQELARR 623
Cdd:PRK03918 642 LEELRKELEELEKK 655
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 314-850 2.52e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.23  E-value: 2.52e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   314 ESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKA-LERLNS-VSKAEKQLETATAEREASNATITDLKSQLARAVSR 391
Cdd:TIGR02168  203 KSLERQAEKAERYKELKAELRELELALLVLRLEELREeLEELQEeLKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   392 AEAAERK-----ARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRR----------EIRDLKEGIEREKERARIREIE 456
Cdd:TIGR02168  283 IEELQKElyalaNEISRLEQQKQILRERLANLERQLEELEAQLEELESkldelaeelaELEEKLEELKEELESLEAELEE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   457 LRGEQSVLESKMESLRSRAEEVSSSAtgeshAKLLRQIEVLQTQYAVASenwhgiegsliARLTAVETERDELERREGDL 536
Cdd:TIGR02168  363 LEAELEELESRLEELEEQLETLRSKV-----AQLELQIASLNNEIERLE-----------ARLERLEDRRERLQQEIEEL 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   537 RRKAREAslKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVVKQDLAkQKEAELTLIQRLEE---- 612
Cdd:TIGR02168  427 LKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARLDSLERLQEnleg 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   613 --ERARWQELARRPSSPFLqePPTGSPITFNRKQTA------GPDPTRPMSDRALSRRS--SSIPPALFSELTTPPYQNH 682
Cdd:TIGR02168  504 fsEGVKALLKNQSGLSGIL--GVLSELISVDEGYEAaieaalGGRLQAVVVENLNAAKKaiAFLKQNELGRVTFLPLDSI 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   683 FSPTNSNPQQPRITPSHEFSGDLTHAQTYEPE-----EYFNGMSTPVTPSAQGT---HTLTHHSRGV---NDIISVSTVA 751
Cdd:TIGR02168  582 KGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalSYLLGGVLVVDDLDNALelaKKLRPGYRIVtldGDLVRPGGVI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   752 AGPSVQ----VVERmSTTIRRLESERAAFKDEIVRLTAQRDEARQEVVELMREVEEKRK--------------------- 806
Cdd:TIGR02168  662 TGGSAKtnssILER-RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKeleelsrqisalrkdlarlea 740

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 240279359   807 ----CDQRIQELEATVEQLDQRYQTTLEMLGEKSEL-------VEELKADISDLK 850
Cdd:TIGR02168  741 eveqLEERIAQLSKELTELEAEIEELEERLEEAEEElaeaeaeIEELEAQIEQLK 795
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
233-623 2.92e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 60.55  E-value: 2.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 233 QEELHAYVERIDALQSKLKYLAKEAAE---SAKNAAASAEAGSLEKKLLEKDEQIANLMEEGQKLSKTELD---HRATIK 306
Cdd:COG4717   94 QEELEELEEELEELEAELEELREELEKlekLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEEleeLEAELA 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 307 KLRQSIAESAKS-QAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLEtATAEREASNATITDLKSQL 385
Cdd:COG4717  174 ELQEELEELLEQlSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE-NELEAAALEERLKEARLLL 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 386 ----------ARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRREIRDL-KEGIEREKERARIRE 454
Cdd:COG4717  253 liaaallallGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELeEEELEELLAALGLPP 332

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 455 IELRGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAVASENwhgiegSLIARLTAVEtERDELERREG 534
Cdd:COG4717  333 DLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEE------ELRAALEQAE-EYQELKEELE 405

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 535 DLRRK--AREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFlvvkQDLAKQKEAElTLIQRLEE 612
Cdd:COG4717  406 ELEEQleELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAEL----EQLEEDGELA-ELLQELEE 480

                        410
                 ....*....|.
gi 240279359 613 ERARWQELARR 623
Cdd:COG4717  481 LKAELRELAEE 491
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
301-575 3.35e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.85  E-value: 3.35e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 301 HRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQ-KALERLNSVSKAEKqLETATAEREASNATIT 379
Cdd:PRK03918 457 YTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQlKELEEKLKKYNLEE-LEKKAEEYEKLKEKLI 535

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 380 DLKSQLARAVSRAE-AAERKARMEATEAEKRQIAELRDDL----------SSAKIEREISE-EKLRR---EIRDLKEGIE 444
Cdd:PRK03918 536 KLKGEIKSLKKELEkLEELKKKLAELEKKLDELEEELAELlkeleelgfeSVEELEERLKElEPFYNeylELKDAEKELE 615

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 445 REKERARIREIEL---RGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAvasenwhgiegSLIARLTA 521
Cdd:PRK03918 616 REEKELKKLEEELdkaFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELA-----------GLRAELEE 684

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 240279359 522 VETERDELERREGDLRRKAREASLKAKKVEgELENSRAVIQEIERNLEASKQEI 575
Cdd:PRK03918 685 LEKRREEIKKTLEKLKEELEEREKAKKELE-KLEKALERVEELREKVKKYKALL 737
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
233-621 4.18e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 60.17  E-value: 4.18e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 233 QEELHAYVERIDALQSKLKYLAKEAAESAKNAAASAEAGSLEKKLLEKDEQIANLMEEGQKLSKTELD---HRATIKKLR 309
Cdd:COG4717   97 LEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELEEEleeLEAELAELQ 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 310 QSIAESAKS-QAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLEtATAEREASNATITDLKSQL--- 385
Cdd:COG4717  177 EELEELLEQlSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE-NELEAAALEERLKEARLLLlia 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 386 -------ARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRREIRDL-KEGIEREKERARIREIEL 457
Cdd:COG4717  256 aallallGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELeEEELEELLAALGLPPDLS 335

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 458 RGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAVASENwhgiegSLIARLTAVEtERDELERREGDLR 537
Cdd:COG4717  336 PEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEE------ELRAALEQAE-EYQELKEELEELE 408

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 538 RK--AREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVVKQD--LAKQKEAELTLIQRLEEE 613
Cdd:COG4717  409 EQleELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDgeLAELLQELEELKAELREL 488


                 ....*...
gi 240279359 614 RARWQELA 621
Cdd:COG4717  489 AEEWAALK 496
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
274-601 4.60e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.08  E-value: 4.60e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 274 EKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEiaeqkalER 353
Cdd:PRK03918 164 YKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE-------EL 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 354 LNSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKAR----MEATEAEKRQIAELRDDLSSAKIEREISE 429
Cdd:PRK03918 237 KEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKelkeLKEKAEEYIKLSEFYEEYLDELREIEKRL 316

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 430 EKLRREIRDLKEGI-EREKERARIREI-----ELRGEQSVLESKME------SLRSRAEEVSSSATGESHAKLLRQIEVL 497
Cdd:PRK03918 317 SRLEEEINGIEERIkELEEKEERLEELkkklkELEKRLEELEERHElyeeakAKKEELERLKKRLTGLTPEKLEKELEEL 396

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 498 QTqyavasenwhgiegsliaRLTAVETERDELERREGDL------RRKAREASLKAKKV------EGELENSRAVIQEIE 565
Cdd:PRK03918 397 EK------------------AKEEIEEEISKITARIGELkkeikeLKKAIEELKKAKGKcpvcgrELTEEHRKELLEEYT 458

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 240279359 566 RNLEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKE 601
Cdd:PRK03918 459 AELKRIEKELKEIEEKERKLRKELRELEKVLKKESE 494
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 273-569 5.84e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.08  E-value: 5.84e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   273 LEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSI-AESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKAL 351
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAE 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   352 ERLnsvSKAEKQLETATAEREASNATITDLKSQlaRAVSRAEAAERKARMEATEAEKRQI----AELRDDLSSAKIEREi 427
Cdd:TIGR02169  322 ERL---AKLEAEIDKLLAEIEELEREIEEERKR--RDKLTEEYAELKEELEDLRAELEEVdkefAETRDELKDYREKLE- 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   428 seeKLRREIRDLKEGIER---EKERARIREIELRGEQSVLESKMESLRSRAEEVsssatGESHAKLLRQIEVLQTQYAVA 504
Cdd:TIGR02169  396 ---KLKREINELKRELDRlqeELQRLSEELADLNAAIAGIEAKINELEEEKEDK-----ALEIKKQEWKLEQLAADLSKY 467

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240279359   505 SEnwhgiegsliaRLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLE 569
Cdd:TIGR02169  468 EQ-----------ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQ 521
PTZ00121 PTZ00121
MAEBL; Provisional
 203-623 8.36e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.77  E-value: 8.36e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  203 VTEPTETSTDDYEEAMAQMRADHEMSELRWQEELHAYVERIDALQSKLKYLAKEAAESAKNAAASAEAGSLEKKLLEKDE 282
Cdd:PTZ00121 1229 VKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAK 1308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  283 QIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRvsqAEIAEQKALERLNSVSKAEK 362
Cdd:PTZ00121 1309 KKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK---AEAAEKKKEEAKKKADAAKK 1385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  363 QLETATAEREASNATITDLKSqlARAVSRAEAAERKARMEATEA-EKRQIAELRDDLSSAKIEREIseEKLRREIRDLKE 441
Cdd:PTZ00121 1386 KAEEKKKADEAKKKAEEDKKK--ADELKKAAAAKKKADEAKKKAeEKKKADEAKKKAEEAKKADEA--KKKAEEAKKAEE 1461

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  442 GIEREKERARIREIELRGEQSV----LESKMESLRSRAEEVSSSATGESHAKLLRQIEvlqtQYAVASENWHGIEGSLIA 517
Cdd:PTZ00121 1462 AKKKAEEAKKADEAKKKAEEAKkadeAKKKAEEAKKKADEAKKAAEAKKKADEAKKAE----EAKKADEAKKAEEAKKAD 1537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  518 RLTAVETERDELERREGDLRRKAREA-SLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVVKQDL 596
Cdd:PTZ00121 1538 EAKKAEEKKKADELKKAEELKKAEEKkKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE 1617

                         410       420
                  ....*....|....*....|....*..
gi 240279359  597 AKQKEAELtliQRLEEERARWQELARR 623
Cdd:PTZ00121 1618 AKIKAEEL---KKAEEEKKKVEQLKKK 1641
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 275-850 1.23e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 1.23e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   275 KKLLEKDEQIANLMEEGQKLSKTELdhRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERL 354
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL--REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   355 NS----VSKAEKQLETATAEREASNATITDLKSQLARAVSRA-EAAERKARMEATEAE-KRQIAELRDDLSSAKIEREIS 428
Cdd:TIGR02168  291 YAlaneISRLEQQKQILRERLANLERQLEELEAQLEELESKLdELAEELAELEEKLEElKEELESLEAELEELEAELEEL 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   429 EEKLRreirDLKEGIEREkeRARIREIE-----LRGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAV 503
Cdd:TIGR02168  371 ESRLE----ELEEQLETL--RSKVAQLElqiasLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   504 ASENWHGIEGSLIARLTAVETERDELErregdlrrKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLT 583
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELE--------EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQS 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   584 KAENDFLVVKQDLAKQKEAELTLIQRLEEeraRWQELARRPSSPFLQEpptgspITFNRKQTAG---------PDPTRPM 654
Cdd:TIGR02168  517 GLSGILGVLSELISVDEGYEAAIEAALGG---RLQAVVVENLNAAKKA------IAFLKQNELGrvtflpldsIKGTEIQ 587

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   655 SDRALSRRSSSIPPALFSELTT--PPYQNHFSP-----------TNSNPQQPRITPSHEF---SGDLTH---AQTYEPEE 715
Cdd:TIGR02168  588 GNDREILKNIEGFLGVAKDLVKfdPKLRKALSYllggvlvvddlDNALELAKKLRPGYRIvtlDGDLVRpggVITGGSAK 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   716 YFNGM------------------------STPVTPSAQGTHTLTHHSRGVNDIISVSTVAAGPSVQVVERMSTTIRRLES 771
Cdd:TIGR02168  668 TNSSIlerrreieeleekieeleekiaelEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE 747

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240279359   772 ERAAFKDEIVRLTAQRDEARQEVVELMREVEEkrkCDQRIQELEATVEQLDQRYQTTLEMLGEKSELVEELKADISDLK 850
Cdd:TIGR02168  748 RIAQLSKELTELEAEIEELEERLEEAEEELAE---AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 272-490 1.65e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.47  E-value: 1.65e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 272 SLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVS--QAEIAEQK 349
Cdd:COG4942   24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAelRAELEAQK 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 350 AL--ERLNSVSKAEKQLETATAEReASNATITDLKSQLARAVSRAeaaeRKARMEATEAEKRQIAELRDDLSSAKIEREI 427
Cdd:COG4942  104 EElaELLRALYRLGRQPPLALLLS-PEDFLDAVRRLQYLKYLAPA----RREQAEELRADLAELAALRAELEAERAELEA 178

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 240279359 428 SEEKLRREIRDLKE----------GIEREKERARIREIELRGEQSVLESKMESLRSRAEEVSSSATGESHAKL 490
Cdd:COG4942  179 LLAELEEERAALEAlkaerqkllaRLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
272-620 2.06e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.13  E-value: 2.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 272 SLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSI----AESAKSQAETK---KRLEKVEKDLVNAEDRVSQAE 344
Cdd:PRK02224 255 TLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERddllAEAGLDDADAEaveARREELEDRDEELRDRLEECR 334

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 345 IAEQKALERLNSVSKAEKQLET---------ATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEKRQIAELR 415
Cdd:PRK02224 335 VAAQAHNEEAESLREDADDLEEraeelreeaAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFL 414

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 416 DDLSSAKIEREISEEKLRREIRDLKEGIErekERARIREI--------------------ELRGEQSVLESKMESLRSRA 475
Cdd:PRK02224 415 EELREERDELREREAELEATLRTARERVE---EAEALLEAgkcpecgqpvegsphvetieEDRERVEELEAELEDLEEEV 491

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 476 EEVSSS-ATGESHAKLLRQIEVLQTQYAVASEnwhgiegsLIA----RLTAVETERDELERREGDLRRKAREASLKAKKV 550
Cdd:PRK02224 492 EEVEERlERAEDLVEAEDRIERLEERREDLEE--------LIAerreTIEEKRERAEELRERAAELEAEAEEKREAAAEA 563

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 551 EGELENSRAVIQEIERNLEASKQEIQNLTRkltkaendflvVKQDLAKQKEAELTlIQRLEEERARWQEL 620
Cdd:PRK02224 564 EEEAEEAREEVAELNSKLAELKERIESLER-----------IRTLLAAIADAEDE-IERLREKREALAEL 621
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 306-586 2.37e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.16  E-value: 2.37e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   306 KKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLnsvSKAEKQLETATAEREASNATITDLKSQL 385
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKI---GEIEKEIEQLEQEEEKLKERLEELEEDL 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   386 -----ARAVSRAEAAERKARMEATEAekrQIAELRDDLssAKIEREISEEK---LRREIRDLKEgiEREKERARIREIEL 457
Cdd:TIGR02169  747 ssleqEIENVKSELKELEARIEELEE---DLHKLEEAL--NDLEARLSHSRipeIQAELSKLEE--EVSRIEARLREIEQ 819

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   458 RGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAvasenwhgiegSLIARLTAVETERDELERREGDLR 537
Cdd:TIGR02169  820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE-----------ELEEELEELEAALRDLESRLGDLK 888

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 240279359   538 RKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAE 586
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIE 937
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 214-547 2.67e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.77  E-value: 2.67e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   214 YEEAMAQMRADH---EMSELRWQEELHAYVERIDALQSKLKYLAKEAAESAKNAAAsaeagsLEKKLLEKDEQIANLMEE 290
Cdd:TIGR02169  672 EPAELQRLRERLeglKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ------LEQEEEKLKERLEELEED 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   291 GQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKAL------------ERLNSVS 358
Cdd:TIGR02169  746 LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEvsriearlreieQKLNRLT 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   359 KAEKQLETATAEREASNATITDLKSQLARAV--SRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRREI 436
Cdd:TIGR02169  826 LEKEYLEKEIQELQEQRIDLKEQIKSIEKEIenLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   437 RDLKEGIEREKERARIREIELrgeQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIE-VLQTQYAVASENWHGIE--- 512
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKL---EALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQrVEEEIRALEPVNMLAIQeye 982

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 240279359   513 ------GSLIARLTAVETERDELERREGDLRRKAREASLKA 547
Cdd:TIGR02169  983 evlkrlDELKEKRAKLEEERKAILERIEEYEKKKREVFMEA 1023
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 355-628 5.70e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 5.70e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 355 NSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKArmeatEAEKRQIAELRDDLssAKIEREISEekLRR 434
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-----AALARRIRALEQEL--AALEAELAE--LEK 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 435 EIRDLKEGIEREKER--ARIREIELRGEQSVLESKMESlrsraeevsssatgESHAKLLRQIEVLQTqyavasenwhgIE 512
Cdd:COG4942   91 EIAELRAELEAQKEElaELLRALYRLGRQPPLALLLSP--------------EDFLDAVRRLQYLKY-----------LA 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 513 GSLIARLTAVETERDELERREGDLRRKAREaslkakkvegeLENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVV 592
Cdd:COG4942  146 PARREQAEELRADLAELAALRAELEAERAE-----------LEALLAELEEERAALEALKAERQKLLARLEKELAELAAE 214

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 240279359 593 KQDLAKQKEAELTLIQRLEEERARwqELARRPSSPF 628
Cdd:COG4942  215 LAELQQEAEELEALIARLEAEAAA--AAERTPAAGF 248
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
327-638 1.42e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.43  E-value: 1.42e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 327 EKVEKDLVNAEDRV-SQAEIAEQKAL-ERLNSVSKAEKQ----LETATAEREASNATITDLKSQLAravsraEAAERKAR 400
Cdd:PRK02224 179 ERVLSDQRGSLDQLkAQIEEKEEKDLhERLNGLESELAEldeeIERYEEQREQARETRDEADEVLE------EHEERREE 252

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 401 MEATEAEkrqIAELRDDLSSAKIEREiseeKLRREIRDLKEGIE--REKERARIREIEL-RGEQSVLESKMESLRSRAEE 477
Cdd:PRK02224 253 LETLEAE---IEDLRETIAETERERE----ELAEEVRDLRERLEelEEERDDLLAEAGLdDADAEAVEARREELEDRDEE 325

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 478 VSssatgeshakllrqiEVLQTQYAVASENWHGIEGsliarltavETER-DELERREGDLRRKAREASLKAKKVEGELEN 556
Cdd:PRK02224 326 LR---------------DRLEECRVAAQAHNEEAES---------LREDaDDLEERAEELREEAAELESELEEAREAVED 381

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 557 SRAVIQEIERNLEASKQEIQNLTRKLTKAE--NDFLVVKQDLAKQKEAEL-TLIQRLEEERARWQELARRPSSPFLQEPP 633
Cdd:PRK02224 382 RREEIEELEEEIEELRERFGDAPVDLGNAEdfLEELREERDELREREAELeATLRTARERVEEAEALLEAGKCPECGQPV 461


                 ....*
gi 240279359 634 TGSPI 638
Cdd:PRK02224 462 EGSPH 466
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 274-619 2.73e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 54.41  E-value: 2.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   274 EKKLLEK--DEQIANLMEEGQK---LSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVS--QAEIA 346
Cdd:pfam01576  153 ERKLLEEriSEFTSNLAEEEEKaksLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAelQAQIA 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   347 EQKAlerlnSVSKAEKQLETA-------TAEREASNATITDLKSQLARAVSRAEaAERKARMEAtEAEKRQIA------- 412
Cdd:pfam01576  233 ELRA-----QLAKKEEELQAAlarleeeTAQKNNALKKIRELEAQISELQEDLE-SERAARNKA-EKQRRDLGeelealk 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   413 -ELRDDLSSAKIEREIsEEKLRREIRDLKEGIEREKERARIREIELRGEQSvleSKMESLRSRAEEVSSSATGESHAKLL 491
Cdd:pfam01576  306 tELEDTLDTTAAQQEL-RSKREQEVTELKKALEEETRSHEAQLQEMRQKHT---QALEELTEQLEQAKRNKANLEKAKQA 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   492 RQIEVLQTQYAVASENWHGIEGSliARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEAS 571
Cdd:pfam01576  382 LESENAELQAELRTLQQAKQDSE--HKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKL 459

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 240279359   572 KQEIQNLTRKLTKAENdflvVKQDLAKQKEAELTLIQRLEEERARWQE 619
Cdd:pfam01576  460 SKDVSSLESQLQDTQE----LLQEETRQKLNLSTRLRQLEDERNSLQE 503
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 233-453 3.16e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 3.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 233 QEELHAYVERIDALQSKLKYLAKEAAesaknaaasaeagSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSI 312
Cdd:COG4942   26 EAELEQLQQEIAELEKELAALKKEEK-------------ALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 313 AESAKSQAETKKRLEKVEKDLVNAEDR------VSQAEIAE-QKALERLNSVSKA-EKQLETATAEREASNATITDLKSQ 384
Cdd:COG4942   93 AELRAELEAQKEELAELLRALYRLGRQpplallLSPEDFLDaVRRLQYLKYLAPArREQAEELRADLAELAALRAELEAE 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 240279359 385 LAR-AVSRAEAAERKARMEATEAEKRQ-IAELRDDLSSAKIEREISEEKlRREIRDLKEGIEREKERARIR 453
Cdd:COG4942  173 RAElEALLAELEEERAALEALKAERQKlLARLEKELAELAAELAELQQE-AEELEALIARLEAEAAAAAER 242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
370-626 3.75e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.15  E-value: 3.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  370 EREASNATITDLKSQLARaVSRAEAAERKARmeateaEKR----QIAELRDDLSSAKIEREISEEkLRREIRDlkEGIER 445
Cdd:COG4913   219 EEPDTFEAADALVEHFDD-LERAHEALEDAR------EQIellePIRELAERYAAARERLAELEY-LRAALRL--WFAQR 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  446 EKERARIREIELRGEQSVLESKMESLRSRAEEvsssatgeshakLLRQIEVLQTQYAvasenwhGIEGSLIARLtavETE 525
Cdd:COG4913   289 RLELLEAELEELRAELARLEAELERLEARLDA------------LREELDELEAQIR-------GNGGDRLEQL---ERE 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  526 RDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKEAelt 605
Cdd:COG4913   347 IERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRE--- 423

                         250       260
                  ....*....|....*....|.
gi 240279359  606 liqrLEEERARwqeLARRPSS 626
Cdd:COG4913   424 ----LEAEIAS---LERRKSN 437
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
305-619 3.87e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.62  E-value: 3.87e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 305 IKKLRQSIAESAKSQAETK----KRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLETATAEREASNATITD 380
Cdd:COG4717   48 LERLEKEADELFKPQGRKPelnlKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 381 LKSQLARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRREIRDLKEGIE-------REKERARIR 453
Cdd:COG4717  128 LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEeelqdlaEELEELQQR 207

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 454 EIELRGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQ----------IEVLQTQYAVASENWHGIEGSLIARLTAVE 523
Cdd:COG4717  208 LAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEarlllliaaaLLALLGLGGSLLSLILTIAGVLFLVLGLLA 287

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 524 TERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKaendfLVVKQDLAKQKEAE 603
Cdd:COG4717  288 LLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEE-----LQELLREAEELEEE 362

                        330
                 ....*....|....*.
gi 240279359 604 LTLIQRLEEERARWQE 619
Cdd:COG4717  363 LQLEELEQEIAALLAE 378
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 272-612 6.44e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.10  E-value: 6.44e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  272 SLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAE--IAEQK 349
Cdd:TIGR04523 215 SLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEkqLNQLK 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  350 A-LERLNS-------------VSKAEKQLETATAEREASNATITDLKSQLARAVSraeaaERKARMEATEAEKRQIAELR 415
Cdd:TIGR04523 295 SeISDLNNqkeqdwnkelkseLKNQEKKLEEIQNQISQNNKIISQLNEQISQLKK-----ELTNSESENSEKQRELEEKQ 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  416 DDLSsaKIEREISE-----EKLRREIRDLKEGIEREKERARIREIELRGEQSVLESKME------SLRSRAEEVSSSATG 484
Cdd:TIGR04523 370 NEIE--KLKKENQSykqeiKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKeierlkETIIKNNSEIKDLTN 447

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  485 ESHAK-------------LLRQIEVLQTQYAVASENWHGIE----------GSLIARLTAVETERDELERREGDLRRKAR 541
Cdd:TIGR04523 448 QDSVKeliiknldntresLETQLKVLSRSINKIKQNLEQKQkelkskekelKKLNEEKKELEEKVKDLTKKISSLKEKIE 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  542 EASLKAKKVEGEL----------------ENSRAVIQEIERNLEASKQEIQNLTRKLTKaendflvvKQDLAKQKEAE-L 604
Cdd:TIGR04523 528 KLESEKKEKESKIsdledelnkddfelkkENLEKEIDEKNKEIEELKQTQKSLKKKQEE--------KQELIDQKEKEkK 599


                  ....*...
gi 240279359  605 TLIQRLEE 612
Cdd:TIGR04523 600 DLIKEIEE 607
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 210-851 8.09e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 8.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   210 STDDYEEAMAQMRAdHEMSELRWQEELHAYVERIDALQSKLKYL--------AKEAAESAKNAAASAEAGSLEKKLLEKD 281
Cdd:TIGR02168  230 LVLRLEELREELEE-LQEELKEAEEELEELTAELQELEEKLEELrlevseleEEIEELQKELYALANEISRLEQQKQILR 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   282 EQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAE---IAEQKALERLNS-V 357
Cdd:TIGR02168  309 ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELEsrlEELEEQLETLRSkV 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   358 SKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRReIR 437
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEE-LR 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   438 DLKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEV-----SSSATGESHAKLLRQIEVlQTQYAVASEN----- 507
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkallkNQSGLSGILGVLSELISV-DEGYEAAIEAalggr 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   508 --------------------------WHGIEGSLIARLTAVETERDELERREGDLRRKAR--EASLKAKKV--------- 550
Cdd:TIGR02168  547 lqavvvenlnaakkaiaflkqnelgrVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDlvKFDPKLRKAlsyllggvl 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   551 ------------------------EGELENSRAVI---------------QEIERN---LEASKQEIQNLTRKLTKAEND 588
Cdd:TIGR02168  627 vvddldnalelakklrpgyrivtlDGDLVRPGGVItggsaktnssilerrREIEELeekIEELEEKIAELEKALAELRKE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   589 FLVVKQDLAKQKEAELTLIQRLEEERARWQELARRPSSPFLQEPPTGSPITFNRKQTAGPDPTRPMSDRALSRRSSSIpp 668
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI-- 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   669 alfsELTTPPYQNHFSPTNSNPQQPRitpshEFSGDLT------HAQTYEPEEYFNGMS---TPVTPSAQGTHTLTHHSR 739
Cdd:TIGR02168  785 ----EELEAQIEQLKEELKALREALD-----ELRAELTllneeaANLRERLESLERRIAateRRLEDLEEQIEELSEDIE 855

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   740 GVNDIISVSTVAAGPSVQVVERMSTTIRRLESERAAFKDEIVRLTAQRDEARQEVVELMREVEEKR----KCDQRIQELE 815
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELReklaQLELRLEGLE 935

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 240279359   816 ATVEQLDQR----YQTTLEMLGEKSELVE----ELKADISDLKK 851
Cdd:TIGR02168  936 VRIDNLQERlseeYSLTLEEAEALENKIEddeeEARRRLKRLEN 979
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 275-612 8.48e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 53.13  E-value: 8.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   275 KKLLEKDEQIANLMEEGQKLSKTELDHRAT-IKKLRQSIA-ESAKSQAETK---KRLE------KVEKDLVNAEDrvSQA 343
Cdd:TIGR01612 1361 KKIIDEVKEYTKEIEENNKNIKDELDKSEKlIKKIKDDINlEECKSKIESTlddKDIDecikkiKELKNHILSEE--SNI 1438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   344 EIAEQKALERLNSVSKAEKQLETATAERE------ASNAT------ITDLKSQLARAVSRAEAAERKARM-----EATEA 406
Cdd:TIGR01612 1439 DTYFKNADENNENVLLLFKNIEMADNKSQhilkikKDNATndhdfnINELKEHIDKSKGCKDEADKNAKAieknkELFEQ 1518

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   407 EKRQIAELRDDLSSAKIEREISEEK-----LRREIRDLKEGIEREKERArireielrgEQSVLESKMESLRSRAEEVSSS 481
Cdd:TIGR01612 1519 YKKDVTELLNKYSALAIKNKFAKTKkdseiIIKEIKDAHKKFILEAEKS---------EQKIKEIKKEKFRIEDDAAKND 1589

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   482 ATGESHAKLLRQIEVLQTQYAVASENWHGIEGSLiarltaveTERDELERREGDLRRKAREASLKAKKVE-GELENSRAV 560
Cdd:TIGR01612 1590 KSNKAAIDIQLSLENFENKFLKISDIKKKINDCL--------KETESIEKKISSFSIDSQDTELKENGDNlNSLQEFLES 1661

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 240279359   561 IQEIERNLEASKQEIQNLTRKLTKAENDflvVKQdlaKQKEAELTLIQRLEE 612
Cdd:TIGR01612 1662 LKDQKKNIEDKKKELDELDSEIEKIEID---VDQ---HKKNYEIGIIEKIKE 1707
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
300-586 1.48e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 1.48e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  300 DHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNsVSKAEKQLETATAER---EASNA 376
Cdd:COG4913   607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEID-VASAEREIAELEAELerlDASSD 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  377 TITDLKSQLARAVSRAEAAERKArmeatEAEKRQIAELRDDLSSAkiereiseEKLRREIRDLKEGIEREKERARIREIE 456
Cdd:COG4913   686 DLAALEEQLEELEAELEELEEEL-----DELKGEIGRLEKELEQA--------EEELDELQDRLEAAEDLARLELRALLE 752

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  457 LRGEQSVLESKMESLRSRAEEVSSSATGEsHAKLLRQIEVLQTQYavaSENWHGIEGSLIARLTAVETERDELERREGD- 535
Cdd:COG4913   753 ERFAAALGDAVERELRENLEERIDALRAR-LNRAEEELERAMRAF---NREWPAETADLDADLESLPEYLALLDRLEEDg 828

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 240279359  536 -LRRKAREASLKAKKVEGELENsraVIQEIERNLEASKQEIQNLTRKLTKAE 586
Cdd:COG4913   829 lPEYEERFKELLNENSIEFVAD---LLSKLRRAIREIKERIDPLNDSLKRIP 877
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
331-563 1.52e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 1.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  331 KDLVNAEDRVSQAEiAEQKALERLNSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEKRQ 410
Cdd:COG4913   235 DDLERAHEALEDAR-EQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELER 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  411 IAELRDDLssakierEISEEKLRREIR----DLKEGIEREKERARIREIELRGEQSVLESKMESLrsraeEVSSSATGES 486
Cdd:COG4913   314 LEARLDAL-------REELDELEAQIRgnggDRLEQLEREIERLERELEERERRRARLEALLAAL-----GLPLPASAEE 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  487 HAKLLRQIEVLQTQYAvasenwhgiegsliARLTAVETERDELERREGDLRRKARE-----ASLKAKK--VEGELENSRA 559
Cdd:COG4913   382 FAALRAEAAALLEALE--------------EELEALEEALAEAEAALRDLRRELREleaeiASLERRKsnIPARLLALRD 447


                  ....
gi 240279359  560 VIQE 563
Cdd:COG4913   448 ALAE 451
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
233-615 2.65e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 2.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 233 QEELHAYVERIDALQSKLKYLAKEAAESAknaaasaeagSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSI 312
Cdd:PRK03918 199 EKELEEVLREINEISSELPELREELEKLE----------KEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERI 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 313 AESAKSQAETK---KRLEKVEKD----------LVNAEDRVSQAEIAEQKALERLNSVSKAEKQLETATAEREASNATIT 379
Cdd:PRK03918 269 EELKKEIEELEekvKELKELKEKaeeyiklsefYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLK 348

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 380 DLKSQLARAVSRAEAAErkaRMEATEAEKRQIAELRDDLSSAKIEREISE-EKLRREIRDlkegiEREKERARIREIELR 458
Cdd:PRK03918 349 ELEKRLEELEERHELYE---EAKAKKEELERLKKRLTGLTPEKLEKELEElEKAKEEIEE-----EISKITARIGELKKE 420

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 459 GEQsvLESKMESLRSRAEE--VSSSATGESHakllrqievlqtqyavasenwhgiEGSLIARLTA----VETERDELERR 532
Cdd:PRK03918 421 IKE--LKKAIEELKKAKGKcpVCGRELTEEH------------------------RKELLEEYTAelkrIEKELKEIEEK 474

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 533 EGDLRRKAREAS---------LKAKKVEGELENSRAVIQEIE-RNLEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKEA 602
Cdd:PRK03918 475 ERKLRKELRELEkvlkkeselIKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEEL 554

                        410
                 ....*....|....*....
gi 240279359 603 ELTL------IQRLEEERA 615
Cdd:PRK03918 555 KKKLaelekkLDELEEELA 573
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
348-856 3.59e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 3.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  348 QKALERLNSVSKAEKQLETATAERE------ASNATITDLKSQLARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSA 421
Cdd:COG4913   228 DALVEHFDDLERAHEALEDAREQIEllepirELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  422 KIEREIseekLRREIRDLKEgiEREKERARIREIELRGEQSvLESKMESLRSRAEEVSssatgESHAKLLRQIEVLQTQY 501
Cdd:COG4913   308 EAELER----LEARLDALRE--ELDELEAQIRGNGGDRLEQ-LEREIERLERELEERE-----RRRARLEALLAALGLPL 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  502 AVASENWHGIEGSLIARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQnltRK 581
Cdd:COG4913   376 PASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALA---EA 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  582 LTKAENDFLVVkqdlakqkeAELtlIQRLEEERaRWQELARRPSSPF----LQEP-------------PTGSPITFNRKQ 644
Cdd:COG4913   453 LGLDEAELPFV---------GEL--IEVRPEEE-RWRGAIERVLGGFaltlLVPPehyaaalrwvnrlHLRGRLVYERVR 520

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  645 TAGPDPTRPmsdrALSRRSssippaLFSELTTPPyqnhfsptnsNPQQPRItpSHEFSGDLTHAQTYEPEEyFNGMSTPV 724
Cdd:COG4913   521 TGLPDPERP----RLDPDS------LAGKLDFKP----------HPFRAWL--EAELGRRFDYVCVDSPEE-LRRHPRAI 577

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  725 TPSAQGTHTLTHHSRGVND------IISVSTVAAgpsvqvvermsttIRRLESERAAFKDEIVRLTAQRDEARQEvvelM 798
Cdd:COG4913   578 TRAGQVKGNGTRHEKDDRRrirsryVLGFDNRAK-------------LAALEAELAELEEELAEAEERLEALEAE----L 640

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 240279359  799 REVEEKRKCDQRIQELEATveqlDQRYQTTLEMLGEKSELVEELKADISDLKKIYREL 856
Cdd:COG4913   641 DALQERREALQRLAEYSWD----EIDVASAEREIAELEAELERLDASSDDLAALEEQL 694
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 279-576 3.95e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.99  E-value: 3.95e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   279 EKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAE-SAKSQAETKKRLEKVEKDLVNAEDRVSQAEiAEQKALERLNSV 357
Cdd:pfam12128  622 AAEEQLVQANGELEKASREETFARTALKNARLDLRRlFDEKQSEKDKKNKALAERKDSANERLNSLE-AQLKQLDKKHQA 700

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   358 SKAEKQ---LETATAEREASNATITDLKSQLARAVSRAEAAE--RKARMEATEAE-KRQIAELRDDlssakierEISEEK 431
Cdd:pfam12128  701 WLEEQKeqkREARTEKQAYWQVVEGALDAQLALLKAAIAARRsgAKAELKALETWyKRDLASLGVD--------PDVIAK 772

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   432 LRREIRDLKEGIER-EKERARIREIElRGEQSVLESKMESLRSRAEEVSSSATgESHAKLLRQIEVLQTQYAVASENWHG 510
Cdd:pfam12128  773 LKREIRTLERKIERiAVRRQEVLRYF-DWYQETWLQRRPRLATQLSNIERAIS-ELQQQLARLIADTKLRRAKLEMERKA 850

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 240279359   511 IEGSLIaRLTAVETERDELERREGDLRRKAREASLkakkvEGELENSRAVIQEIERNLEASKQEIQ 576
Cdd:pfam12128  851 SEKQQV-RLSENLRGLRCEMSKLATLKEDANSEQA-----QGSIGERLAQLEDLKLKRDYLSESVK 910
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 275-650 6.44e-06

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 50.01  E-value: 6.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 275 KKLLEKDEQIANLmEEGQKLS--KTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEiaeqkale 352
Cdd:NF033838  75 QKSLDKRKHTQNV-ALNKKLSdiKTEYLYELNVLKEKSEAELTSKTKKELDAAFEQFKKDTLEPGKKVAEAT-------- 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 353 rlNSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEKRQiAELRDDLSSAKIEREISEEKL 432
Cdd:NF033838 146 --KKVEEAEKKAKDQKEEDRRNYPTNTYKTLELEIAESDVEVKKAELELVKEEAKEPR-DEEKIKQAKAKVESKKAEATR 222

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 433 RREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEvssSATGESHAKLLRQIEVLQTQYAVASENWHGIE 512
Cdd:NF033838 223 LEKIKTDREKAEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKR---GVLGEPATPDKKENDAKSSDSSVGEETLPSPS 299

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 513 GSLIARLTAVETERDELERREGDLRRKARE--ASLKAKKVEGELENSRAVIQEIErnLEASKQEiqnltrklTKAENDFL 590
Cdd:NF033838 300 LKPEKKVAEAEKKVEEAKKKAKDQKEEDRRnyPTNTYKTLELEIAESDVKVKEAE--LELVKEE--------AKEPRNEE 369

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 240279359 591 VVKQDLAK--QKEAELTLIQRLEEERARWQELARRPSSPF--LQEPPTGSPITFNRKQTAGPDP 650
Cdd:NF033838 370 KIKQAKAKveSKKAEATRLEKIKTDRKKAEEEAKRKAAEEdkVKEKPAEQPQPAPAPQPEKPAP 433
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
305-454 7.49e-06

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 49.49  E-value: 7.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 305 IKKLRQSIAESAKSQAETKKRLEKVEKdlvNAEDRVSQAEIAEQKALERLnSVSKAEKQLETATAEREAsnatitdlKSQ 384
Cdd:COG2268  191 RRKIAEIIRDARIAEAEAERETEIAIA---QANREAEEAELEQEREIETA-RIAEAEAELAKKKAEERR--------EAE 258

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 385 LARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRREIRdlkEGIEREKERARIRE 454
Cdd:COG2268  259 TARAEAEAAYEIAEANAEREVQRQLEIAEREREIELQEKEAEREEAELEADVR---KPAEAEKQAAEAEA 325
PTZ00121 PTZ00121
MAEBL; Provisional
 215-595 9.67e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 9.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  215 EEAMAQMRADHEMSELRWQEELHAYVE---RIDALQSKLKYLAKEAAESAKNAAASAEAGSLEKKLLEKDEqiANLMEEG 291
Cdd:PTZ00121 1441 EEAKKADEAKKKAEEAKKAEEAKKKAEeakKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKK--ADEAKKA 1518

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  292 QKLSKTELDHRATIKKLrqsiAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLETATAER 371
Cdd:PTZ00121 1519 EEAKKADEAKKAEEAKK----ADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI 1594

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  372 EASNATITDLKSQLARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRREIRDLKEGIEREKERAR 451
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  452 IREIELRGEQSVLESKMESLRSRAEEVsssatgeshakllRQIEVLQTQYAVASENWHGIEGSLIARLTAVEterdELER 531
Cdd:PTZ00121 1675 KKAEEAKKAEEDEKKAAEALKKEAEEA-------------KKAEELKKKEAEEKKKAEELKKAEEENKIKAE----EAKK 1737

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 240279359  532 REGDLRRKAREaslkAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVVKQD 595
Cdd:PTZ00121 1738 EAEEDKKKAEE----AKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVD 1797
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 231-620 1.06e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.30  E-value: 1.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   231 RWQEELHAYVERIDALQSKLKYLAKEAAESAKNAAAsaeagsLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQ 310
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREINELKRELDRLQEELQR------LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW 455

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   311 SIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLETATAEREASNATITDLKSQLAR--- 387
Cdd:TIGR02169  456 KLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSvge 535

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   388 ----AVSRAEAAERKARMEATEAEKRQIAELrddLSSAKIERE--ISEEKLRREIRDL----KEG--------IEREKER 449
Cdd:TIGR02169  536 ryatAIEVAAGNRLNNVVVEDDAVAKEAIEL---LKRRKAGRAtfLPLNKMRDERRDLsilsEDGvigfavdlVEFDPKY 612

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   450 ARI-----------REIELrGEQSVLESKMESLRSRAEEVSSSATGeSHAKLLRQIEVLQTQYAVASENWHGIEG----- 513
Cdd:TIGR02169  613 EPAfkyvfgdtlvvEDIEA-ARRLMGKYRMVTLEGELFEKSGAMTG-GSRAPRGGILFSRSEPAELQRLRERLEGlkrel 690

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   514 -SLIARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVV 592
Cdd:TIGR02169  691 sSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                          410       420
                   ....*....|....*....|....*...
gi 240279359   593 KQDLAKQKEAELTLIQRLEEEraRWQEL 620
Cdd:TIGR02169  771 EEDLHKLEEALNDLEARLSHS--RIPEI 796
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 229-616 1.15e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 49.25  E-value: 1.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  229 ELRWQEELHAYV-ERIDALQSKLKYL-AKEAAESAKNAAASAEAGSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIK 306
Cdd:TIGR04523 132 QKKENKKNIDKFlTEIKKKEKELEKLnNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQ 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  307 KLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLETATAEREASNATITDLKSQLA 386
Cdd:TIGR04523 212 KNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLN 291

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  387 RAVSRAEA----------AERKARMEATEAEKRQ-----------IAELRDDLSSAKIEREISE---EKLRREIRDLK-- 440
Cdd:TIGR04523 292 QLKSEISDlnnqkeqdwnKELKSELKNQEKKLEEiqnqisqnnkiISQLNEQISQLKKELTNSEsenSEKQRELEEKQne 371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  441 -EGIEREKErARIREIE-LRGEQSVLESKMESLRSRAEEVSSSATG--ESHAKLLRQIEVLQTQYAVASENwhgIEgSLI 516
Cdd:TIGR04523 372 iEKLKKENQ-SYKQEIKnLESQINDLESKIQNQEKLNQQKDEQIKKlqQEKELLEKEIERLKETIIKNNSE---IK-DLT 446

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  517 ARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENsraviqeIERNLEASKQEIQNLTRKLTKAENDFlvvkQDL 596
Cdd:TIGR04523 447 NQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ-------KQKELKSKEKELKKLNEEKKELEEKV----KDL 515

                         410       420
                  ....*....|....*....|
gi 240279359  597 AKQKEAELTLIQRLEEERAR 616
Cdd:TIGR04523 516 TKKISSLKEKIEKLESEKKE 535
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 311-544 1.69e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 48.80  E-value: 1.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  311 SIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLETATAEREASNA--TITDLKSQLARA 388
Cdd:COG3096   435 TPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERSQAWQTARELlrRYRSQQALAQRL 514

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  389 VS-RAEAAERKARMEATEAEKRQIAELrDDLSSAKIEREISEEKLRREIRDLKEGIEREKERARIREIELRGEQSVLESK 467
Cdd:COG3096   515 QQlRAQLAELEQRLRQQQNAERLLEEF-CQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRAR 593

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  468 MESLRSRAeevssSATGESHAKLLRqievLQTQYAVASENWHGIEG---SLIARLTAVETERDELERREGDLRRKAREAS 544
Cdd:COG3096   594 IKELAARA-----PAWLAAQDALER----LREQSGEALADSQEVTAamqQLLEREREATVERDELAARKQALESQIERLS 664
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
241-441 2.05e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 2.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  241 ERIDALQSKLKYLAKEAAESAKNAAASaeagsleKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAEsaksqa 320
Cdd:COG4913   610 AKLAALEAELAELEEELAEAEERLEAL-------EAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAE------ 676

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  321 etKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLETataEREASNATITDLKSQLARAVS------RAEA 394
Cdd:COG4913   677 --LERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEK---ELEQAEEELDELQDRLEAAEDlarlelRALL 751

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 240279359  395 AERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRREIRDLKE 441
Cdd:COG4913   752 EERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNR 798
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
274-623 2.25e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.11  E-value: 2.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 274 EKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAE--IAEQK-- 349
Cdd:PRK02224 376 REAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEalLEAGKcp 455

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 350 --------------ALERLNSVSKAEKQLETATAEREasnatitDLKSQLARAVSRAEAAERKARMEateaEKRQIAELR 415
Cdd:PRK02224 456 ecgqpvegsphvetIEEDRERVEELEAELEDLEEEVE-------EVEERLERAEDLVEAEDRIERLE----ERREDLEEL 524

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 416 ddlssakiereiseeklrreIRDLKEGIEREKERARireiELRGEQSVLESKMESLRSRAEEVSSSAtgESHAKLLRQIE 495
Cdd:PRK02224 525 --------------------IAERRETIEEKRERAE----ELRERAAELEAEAEEKREAAAEAEEEA--EEAREEVAELN 578

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 496 VLQTQYAVASENWHGIEGSLiARLTAVETERDEL-ERREG-----DLRR-KAREASLKAKKVEGELENSRavIQEIERNL 568
Cdd:PRK02224 579 SKLAELKERIESLERIRTLL-AAIADAEDEIERLrEKREAlaelnDERReRLAEKRERKRELEAEFDEAR--IEEAREDK 655

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 240279359 569 EASKQEIQNLTRKLTKAENDflvvKQDLAKQKEAELTLIQRLEEERARWQELARR 623
Cdd:PRK02224 656 ERAEEYLEQVEEKLDELREE----RDDLQAEIGAVENELEELEELRERREALENR 706
PTZ00121 PTZ00121
MAEBL; Provisional
 264-586 2.95e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 2.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  264 AAASAEAGSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQA 343
Cdd:PTZ00121 1202 AEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKAD 1281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  344 EIAEQKALERLNSVSKAEKQLETATAEREASNATITD-LKSQLARAVSRAEAAERKA--RMEATEAEKRQIAELRDDLSS 420
Cdd:PTZ00121 1282 ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADeAKKKAEEAKKKADAAKKKAeeAKKAAEAAKAEAEAAADEAEA 1361

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  421 AKIEREISEEKLRREIRDLKEGIEREKERARIREIELRGEQ-----------SVLESKMESLRSRAEEVSSSATGESHAK 489
Cdd:PTZ00121 1362 AEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEdkkkadelkkaAAAKKKADEAKKKAEEKKKADEAKKKAE 1441

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  490 LLRQIEVL--QTQYAVASENwhgiegsliARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERN 567
Cdd:PTZ00121 1442 EAKKADEAkkKAEEAKKAEE---------AKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA 1512

                         330
                  ....*....|....*....
gi 240279359  568 LEASKQEIQNLTRKLTKAE 586
Cdd:PTZ00121 1513 DEAKKAEEAKKADEAKKAE 1531
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
396-616 3.88e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.37  E-value: 3.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 396 ERKARMEATEAEKRQIAELRDDLSS--AKIEREISE-EKLRREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLR 472
Cdd:PRK03918 197 EKEKELEEVLREINEISSELPELREelEKLEKEVKElEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE 276

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 473 SRAEEVSSSATGESHAKLLRQIEVLQTQYAVASENWHGIEGSLIARLTAVETERDELERREGDLRrkareaslKAKKVEG 552
Cdd:PRK03918 277 ELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLE--------ELKKKLK 348

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 240279359 553 ELENSRAVIQEIERNLEASKQ---EIQNLTRKLTKAENDFLVVKQDLAKQKEAELTL-IQRLEEERAR 616
Cdd:PRK03918 349 ELEKRLEELEERHELYEEAKAkkeELERLKKRLTGLTPEKLEKELEELEKAKEEIEEeISKITARIGE 416
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 276-443 5.07e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.69  E-value: 5.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 276 KLLEKDEQIANLMEEGQKLskteldhRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLN 355
Cdd:COG1579   11 DLQELDSELDRLEHRLKEL-------PAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 356 SVSKA------EKQLETATAEREASNATITDLKSQLARAVSR-----AEAAERKARMEATEAE-KRQIAELRDDLSSAKI 423
Cdd:COG1579   84 NVRNNkeyealQKEIESLKRRISDLEDEILELMERIEELEEElaeleAELAELEAELEEKKAElDEELAELEAELEELEA 163

                        170       180
                 ....*....|....*....|
gi 240279359 424 EREISEEKLRREIRDLKEGI 443
Cdd:COG1579  164 EREELAAKIPPELLALYERI 183
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 271-409 6.91e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.30  E-value: 6.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 271 GSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKV---------EKDLVNAEDRVS 341
Cdd:COG1579   27 KELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVrnnkeyealQKEIESLKRRIS 106

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 240279359 342 QAEIAEQKALERLnsvSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEKR 409
Cdd:COG1579  107 DLEDEILELMERI---EELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 380-623 7.38e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.76  E-value: 7.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   380 DLKSQLARAVSRAEAAERKARMEATEAEKR------QIAELRDDLSSAKIEREISEEKLRR-------EIRDLKEGIERE 446
Cdd:pfam12128  597 ASEEELRERLDKAEEALQSAREKQAAAEEQlvqangELEKASREETFARTALKNARLDLRRlfdekqsEKDKKNKALAER 676

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   447 KERARIREIELRGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAVASENWHGIEGSLIARLTAVETER 526
Cdd:pfam12128  677 KDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWY 756

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   527 DElerregdlrrkareaSLKAKKVEGElensraviqeierNLEASKQEIQNLTRKLTKAEND--------------FLVV 592
Cdd:pfam12128  757 KR---------------DLASLGVDPD-------------VIAKLKREIRTLERKIERIAVRrqevlryfdwyqetWLQR 808

                          250       260       270
                   ....*....|....*....|....*....|.
gi 240279359   593 KQDLAKQKEAELTLIQRLEEERARWQELARR 623
Cdd:pfam12128  809 RPRLATQLSNIERAISELQQQLARLIADTKL 839
PilO COG3167
Type IV pilus assembly protein PilO [Cell motility, Extracellular structures];
785-849 7.74e-05

Type IV pilus assembly protein PilO [Cell motility, Extracellular structures];


Pssm-ID: 442400 [Multi-domain]  Cd Length: 202  Bit Score: 44.55  E-value: 7.74e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240279359 785 AQRDEARQEVVELMREVEEKRKCDQRIQELEATVEQLDQRYQTTLEMLGEKSElVEELKADISDL 849
Cdd:COG3167   46 EELEELEAEEAQLKQELEKKQAKAANLPALKAQLEELEQQLGELLKQLPSKAE-VPALLDDISQA 109
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 398-623 7.81e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.50  E-value: 7.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   398 KARMEATEAEKRQIAELRDDLSSAKIEREISEEKL-RREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLRS--- 473
Cdd:pfam02463  168 KRKKKEALKKLIEETENLAELIIDLEELKLQELKLkEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEllr 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   474 --RAEEVSSSATGESHAKLLRQIEVLQTQYAVASENWHGIEGSLIARLTAVETERDELERREGDLRRKAREASLKAKKVE 551
Cdd:pfam02463  248 deQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAE 327

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240279359   552 GELENSRAVIQEIE-------RNLEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERARWQELARR 623
Cdd:pfam02463  328 KELKKEKEEIEELEkelkeleIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKE 406
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 271-620 7.87e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.50  E-value: 7.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   271 GSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLE---KVEKDLVNAEDRVSQAEIAE 347
Cdd:pfam02463  667 SLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLadrVQEAQDKINEELKLLKQKID 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   348 QKALERLNSVSKAEKQLETA-------TAEREASNATITDLKSQLARAVSRAEAAERKARMEA-TEAEKRQIAELRDDLS 419
Cdd:pfam02463  747 EEEEEEEKSRLKKEEKEEEKselslkeKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEElKEEAELLEEEQLLIEQ 826

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   420 SAKIEREISEEKLRREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQT 499
Cdd:pfam02463  827 EEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEES 906

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   500 QYAVASENWHGIEGSLIARLTAVETERDELERRegdlrrkareaSLKAKKVEGELENSRAVIQEIERNLEasKQEIQNLT 579
Cdd:pfam02463  907 QKLNLLEEKENEIEERIKEEAEILLKYEEEPEE-----------LLLEEADEKEKEENNKEEEEERNKRL--LLAKEELG 973

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 240279359   580 RKLTKAENDFlvvkQDLAKQKEAELTLIQRLEEERARWQEL 620
Cdd:pfam02463  974 KVNLMAIEEF----EEKEERYNKDELEKERLEEEKKKLIRA 1010
46 PHA02562
endonuclease subunit; Provisional
 283-436 8.21e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.16  E-value: 8.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 283 QIANLMEEGQKLSKTELDHRATIKKLRQSIAEsAKSQAETKKRLEKVEKD-----------------LVNAEDRVSQAEI 345
Cdd:PHA02562 235 EIEELTDELLNLVMDIEDPSAALNKLNTAAAK-IKSKIEQFQKVIKMYEKggvcptctqqisegpdrITKIKDKLKELQH 313

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 346 AEQKALERLNSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAErkARMEATEAE----KRQIAELRDDLSSA 421
Cdd:PHA02562 314 SLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVK--AAIEELQAEfvdnAEELAKLQDELDKI 391

                        170
                 ....*....|....*.
gi 240279359 422 KIER-EISEEKLRREI 436
Cdd:PHA02562 392 VKTKsELVKEKYHRGI 407
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
279-551 1.37e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.80  E-value: 1.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 279 EKDEQIANLMEEgqkLSKTELDHRATIKKLrqsiaESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVS 358
Cdd:PRK02224 472 EDRERVEELEAE---LEDLEEEVEEVEERL-----ERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELR 543

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 359 KAEKQLETATAEREASNAtitdlKSQLARAVSRAEAAERKARMEATEAEKRQIAELRDDLSS-AKIEREISEEKLRREIR 437
Cdd:PRK02224 544 ERAAELEAEAEEKREAAA-----EAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAiADAEDEIERLREKREAL 618

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 438 DLKEGIEREK---ERARIREIELRGEQSVLEsKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAVASE-------- 506
Cdd:PRK02224 619 AELNDERRERlaeKRERKRELEAEFDEARIE-EAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEleeleelr 697

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 240279359 507 NWHGIEGSLIARLTAVETERDELERREGDLRrkareASLKAKKVE 551
Cdd:PRK02224 698 ERREALENRVEALEALYDEAEELESMYGDLR-----AELRQRNVE 737
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
233-445 1.37e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 1.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  233 QEELHAYVERIDALQSKLKYLAKEAAESAKNAAASAEA---GSLEKKLLEKDEQIANLMEEGQKLS--KTELDH-RATIK 306
Cdd:COG4913   623 EEELAEAEERLEALEAELDALQERREALQRLAEYSWDEidvASAEREIAELEAELERLDASSDDLAalEEQLEElEAELE 702

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  307 KLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALE-------RLNSVSKAEKQL-ETATAEREASNATI 378
Cdd:COG4913   703 ELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRalleerfAAALGDAVERELrENLEERIDALRARL 782

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  379 TDLKSQLARAVSR------AEAAERKARMEATEA--------EKRQIAELRDDLSSAKIEREISE-----EKLRREIRDL 439
Cdd:COG4913   783 NRAEEELERAMRAfnrewpAETADLDADLESLPEylalldrlEEDGLPEYEERFKELLNENSIEFvadllSKLRRAIREI 862


                  ....*.
gi 240279359  440 KEGIER 445
Cdd:COG4913   863 KERIDP 868
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 307-623 1.42e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.71  E-value: 1.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  307 KLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQ----------LETATAEREASNA 376
Cdd:COG3096   289 ELRRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQqekieryqedLEELTERLEEQEE 368

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  377 TITDLKSQLARAVSRAEAAErkarmEATEAEKRQIAELR---DDLSSAKIEREISEEKLRR-----EIRDLK-EGIEREK 447
Cdd:COG3096   369 VVEEAAEQLAEAEARLEAAE-----EEVDSLKSQLADYQqalDVQQTRAIQYQQAVQALEKaralcGLPDLTpENAEDYL 443

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  448 ERARIREIELRGEQSVLESKM--------------ESLRSRAEEVSSSATGESHAKLLRQIEVLQtqyavasenwhgieg 513
Cdd:COG3096   444 AAFRAKEQQATEEVLELEQKLsvadaarrqfekayELVCKIAGEVERSQAWQTARELLRRYRSQQ--------------- 508

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  514 SLIARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSraviQEIERNLEASKQEIQNLTrkltkaendflvvk 593
Cdd:COG3096   509 ALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAA----EELEELLAELEAQLEELE-------------- 570

                         330       340       350
                  ....*....|....*....|....*....|
gi 240279359  594 QDLAKQKEAELTLIQRLEEERARWQELARR 623
Cdd:COG3096   571 EQAAEAVEQRSELRQQLEQLRARIKELAAR 600
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 312-481 1.51e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.15  E-value: 1.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 312 IAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAeqkalerlnsVSKAEKQLETATAEREASNATITDLKSQLARAVSr 391
Cdd:COG1579   19 LDRLEHRLKELPAELAELEDELAALEARLEAAKTE----------LEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRN- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 392 aeAAERKARMEATEAEKRQIAELRDDLSSAKIEREiseeKLRREIRDLKEGIEREKERARIREIELRGEQSVLESKMESL 471
Cdd:COG1579   88 --NKEYEALQKEIESLKRRISDLEDEILELMERIE----ELEEELAELEAELAELEAELEEKKAELDEELAELEAELEEL 161

                        170
                 ....*....|
gi 240279359 472 RSRAEEVSSS 481
Cdd:COG1579  162 EAEREELAAK 171
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 407-623 2.52e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 2.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   407 EKRQIAELRDDLSSAKIEREiseEKLRREIRDLKEGIEREKERA-RIREIELRGEQ---SVLESKMESLRSRAEEVSSSA 482
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRL---EDILNELERQLKSLERQAEKAeRYKELKAELRElelALLVLRLEELREELEELQEEL 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   483 tgeshAKLLRQIEVLQTQYAVASEnwhgiegsliaRLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQ 562
Cdd:TIGR02168  249 -----KEAEEELEELTAELQELEE-----------KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 240279359   563 EIERNLEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERARWQELARR 623
Cdd:TIGR02168  313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
273-451 2.56e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 2.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  273 LEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAksqaetKKRLEKVEKDLVNAEDRVSQAEiaeqKALE 352
Cdd:COG4913   293 LEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNG------GDRLEQLEREIERLERELEERE----RRRA 362

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  353 RLnsvskaEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEkRQIAELRDDLssakiereiseEKL 432
Cdd:COG4913   363 RL------EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAE-AALRDLRREL-----------REL 424

                         170       180
                  ....*....|....*....|..
gi 240279359  433 RREIRDLKEG---IEREKERAR 451
Cdd:COG4913   425 EAEIASLERRksnIPARLLALR 446
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 274-577 3.03e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 44.34  E-value: 3.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  274 EKKLLEKDEQIANLMEEGQKLSKTELDHRATIkklrqsIAESAKSQAETKKRLEKVEKDLVNAE-DRVSQAEIAEQkaLE 352
Cdd:pfam17380 304 EKEEKAREVERRRKLEEAEKARQAEMDRQAAI------YAEQERMAMERERELERIRQEERKRElERIRQEEIAME--IS 375

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  353 RLnsvskaeKQLETATAEREASNatitdlksqlARAVSRAEAAERKARMEatEAEKRQIAELRDDLSSAKIEReisEEKL 432
Cdd:pfam17380 376 RM-------RELERLQMERQQKN----------ERVRQELEAARKVKILE--EERQRKIQQQKVEMEQIRAEQ---EEAR 433

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  433 RREIRDLKEGIEREKERARIREIELRGEQSVL-----ESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAVASEN 507
Cdd:pfam17380 434 QREVRRLEEERAREMERVRLEEQERQQQVERLrqqeeERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEER 513

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 240279359  508 WHGI-EGSLIARLTAVETERdelERREGDLRRKAREASLKAKKVEGELENS---RAVIQEIERNLEASKQEIQN 577
Cdd:pfam17380 514 KRKLlEKEMEERQKAIYEEE---RRREAEEERRKQQEMEERRRIQEQMRKAteeRSRLEAMEREREMMRQIVES 584
AtpF COG0711
FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]; FoF1-type ...
 323-443 3.32e-04

FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit b or b' is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440475 [Multi-domain]  Cd Length: 152  Bit Score: 41.70  E-value: 3.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 323 KKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSV-SKAEKQLETATAEREA-SNATITDLKSQLARAVSRAEAAERKAR 400
Cdd:COG0711   30 DERQEKIADGLAEAERAKEEAEAALAEYEEKLAEArAEAAEIIAEARKEAEAiAEEAKAEAEAEAERIIAQAEAEIEQER 109

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 240279359 401 MEATEAEKRQIAELRDDLSSAKIEREISEEKLRREIRDLKEGI 443
Cdd:COG0711  110 AKALAELRAEVADLAVAIAEKILGKELDAAAQAALVDRFIAEL 152
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 233-610 3.40e-04

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 44.36  E-value: 3.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  233 QEELHAYVERIDALQSKLKylAKEAAESAKNAAASAEAGSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSI 312
Cdd:pfam07111 305 RSLLNRWREKVFALMVQLK--AQDLEHRDSVKQLRGQVAELQEQVTSQSQEQAILQRALQDKAAEVEVERMSAKGLQMEL 382

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  313 AESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNsvsKAEKQLETATAEREASNATITDLKSQLARAVS-- 390
Cdd:pfam07111 383 SRAQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRVE---QAVARIPSLSNRLSYAVRKVHTIKGLMARKVAla 459

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  391 --RAEAAERKARMEATEAE-KRQIAELRDDLSSAKIEREISEEKLRREIRDLKEgiEREKERARIREIELRGEQSvLESK 467
Cdd:pfam07111 460 qlRQESCPPPPPAPPVDADlSLELEQLREERNRLDAELQLSAHLIQQEVGRARE--QGEAERQQLSEVAQQLEQE-LQRA 536

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  468 MESLRSRAEEVSSSATGESH----AKLLRQiEVLQTQYAVASenwhgiegSLIARLTAVETE-RDEL---ERREGDLRRK 539
Cdd:pfam07111 537 QESLASVGQQLEVARQGQQEsteeAASLRQ-ELTQQQEIYGQ--------ALQEKVAEVETRlREQLsdtKRRLNEARRE 607

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240279359  540 AREASLKAKKVEGELENSRAVIQEIER-NLEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRL 610
Cdd:pfam07111 608 QAKAVVSLRQIQHRATQEKERNQELRRlQDEARKEEGQRLARRVQELERDKNLMLATLQQEGLLSRYKQQRL 679
PRK12704 PRK12704
phosphodiesterase; Provisional
 358-497 3.65e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.00  E-value: 3.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 358 SKAEKQLETAtaEREAsnatitdlKSQLARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRREir 437
Cdd:PRK12704  27 KIAEAKIKEA--EEEA--------KRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQK-- 94

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 438 dlKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEVSssatgESHAKLLRQIEVL 497
Cdd:PRK12704  95 --EENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELE-----ELIEEQLQELERI 147
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
408-612 3.75e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 3.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 408 KRQIAELRDDLSSAK--IEREIseEKLRREIRDLKEGIEREKERARIreIELRGEQSVLESKMESLRSRAEEVSSSAtge 485
Cdd:COG3206  163 EQNLELRREEARKALefLEEQL--PELRKELEEAEAALEEFRQKNGL--VDLSEEAKLLLQQLSELESQLAEARAEL--- 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 486 shAKLLRQIEVLQTQYAVASENWHGIEGSliARLTAVETERDELERREGDLRR------------KAREASLKA------ 547
Cdd:COG3206  236 --AEAEARLAALRAQLGSGPDALPELLQS--PVIQQLRAQLAELEAELAELSArytpnhpdvialRAQIAALRAqlqqea 311

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240279359 548 KKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRLEE 612
Cdd:COG3206  312 QRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEE 376
CCCAP pfam15964
Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ...
 303-595 4.15e-04

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.


Pssm-ID: 435040 [Multi-domain]  Cd Length: 703  Bit Score: 44.13  E-value: 4.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  303 ATIKKLRQSIAESAKSQAETKKRLEKVEKDLV-NAEDRVSQA--EIAEQKALERLNSVSKAEKQLETATAEREASNATIT 379
Cdd:pfam15964 238 SQVKSLRKDLAESQKTCEDLKERLKHKESLVAaSTSSRVGGLclKCAQHEAVLAQTHTNVHMQTIERLTKERDDLMSALV 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  380 DLKSQLARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREIS--EEKLRREIRDLKEGIEREKERARIreiEL 457
Cdd:pfam15964 318 SVRSSLAEAQQRESSAYEQVKQAVQMTEEANFEKTKALIQCEQLKSELErqKERLEKELASQQEKRAQEKEALRK---EM 394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  458 RGEQSVLESKMESLRSRAEEVSSSATGESHAK--LLRQIEVLQTQYAVASENWHGIEGSLIARLTAVETERDELERREGD 535
Cdd:pfam15964 395 KKEREELGATMLALSQNVAQLEAQVEKVTREKnsLVSQLEEAQKQLASQEMDVTKVCGEMRYQLNQTKMKKDEAEKEHRE 474

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 240279359  536 LRRKA-REASLKAKKVEG---ELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVVKQD 595
Cdd:pfam15964 475 YRTKTgRQLEIKDQEIEKlglELSESKQRLEQAQQDAARAREECLKLTELLGESEHQLHLTRLE 538
mukB PRK04863
chromosome partition protein MukB;
320-589 4.26e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.18  E-value: 4.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  320 AETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLetATAEREASNATITDLKSQLARAvSRAEAAERKA 399
Cdd:PRK04863  840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRL--NLLADETLADRVEEIREQLDEA-EEAKRFVQQH 916

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  400 RMEATEAEK---------RQIAELRDDLSSAKIEREiseeKLRREIRDLKEGIEREKERARIREIELRGEQSVLESKMES 470
Cdd:PRK04863  917 GNALAQLEPivsvlqsdpEQFEQLKQDYQQAQQTQR----DAKQQAFALTEVVQRRAHFSYEDAAEMLAKNSDLNEKLRQ 992

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  471 LRSRAEEVSSSATGEshaklLRQIEVLQTQYavasenwHGIEGSLIARLTAVETERDELERREGDLRRKARE-----ASL 545
Cdd:PRK04863  993 RLEQAEQERTRAREQ-----LRQAQAQLAQY-------NQVLASLKSSYDAKRQMLQELKQELQDLGVPADSgaeerARA 1060

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 240279359  546 KAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDF 589
Cdd:PRK04863 1061 RRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDY 1104
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
277-851 5.34e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.88  E-value: 5.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 277 LLEKDEQIANlmEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEkvEKDLVNAEDRVSQAEIAEQKAlerlnS 356
Cdd:PRK02224 189 LDQLKAQIEE--KEEKDLHERLNGLESELAELDEEIERYEEQREQARETRD--EADEVLEEHEERREELETLEA-----E 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 357 VSKAEKQLETATAEREASNATITDLKSQLARAvsRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRREI 436
Cdd:PRK02224 260 IEDLRETIAETEREREELAEEVRDLRERLEEL--EEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAA 337

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 437 RDLKEGIEREKERARIRE---IELRGEQSVLESKMESLRSRAEEVSSsatgeshakllrQIEVLQTQYAVASENWHGIEg 513
Cdd:PRK02224 338 QAHNEEAESLREDADDLEeraEELREEAAELESELEEAREAVEDRRE------------EIEELEEEIEELRERFGDAP- 404

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 514 sliARLTAVETERDELERREGDLRrkAREASLKAkkvegELENSRAVIQEIERNLEASK-----QEIQNLTRKLTKAEND 588
Cdd:PRK02224 405 ---VDLGNAEDFLEELREERDELR--EREAELEA-----TLRTARERVEEAEALLEAGKcpecgQPVEGSPHVETIEEDR 474

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 589 FLVVK--QDLAKQKEAELTLIQRLEEERArWQELARRPSSpfLQEpptgspitfnrkqtagpdpTRPMSDRALSRRSSSI 666
Cdd:PRK02224 475 ERVEEleAELEDLEEEVEEVEERLERAED-LVEAEDRIER--LEE-------------------RREDLEELIAERRETI 532

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 667 ppalfselttppyqnhfsptnsNPQQPRITPSHEFSGDL-THAQTYEPEeyfngmstpvtpsAQGTHTLTHHSRGVNDII 745
Cdd:PRK02224 533 ----------------------EEKRERAEELRERAAELeAEAEEKREA-------------AAEAEEEAEEAREEVAEL 577

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 746 SVSTVAAGPSVQVVERmsttIRRLESERAAFKDEIVRLTAQRdEARQEVVELMRE-VEEKRkcdQRIQELEAT-----VE 819
Cdd:PRK02224 578 NSKLAELKERIESLER----IRTLLAAIADAEDEIERLREKR-EALAELNDERRErLAEKR---ERKRELEAEfdearIE 649

                        570       580       590
                 ....*....|....*....|....*....|..
gi 240279359 820 QLDQRYQTTLEMLGEKSELVEELKADISDLKK 851
Cdd:PRK02224 650 EAREDKERAEEYLEQVEEKLDELREERDDLQA 681
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 277-606 5.43e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 5.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  277 LLEKDEQIANLMEEGQKLS----KTELDHRATIKKLRQSIAESAKSQAETKKRLEKvekDLVNAEDRVSQAEIAEQKALE 352
Cdd:pfam05483 262 LLEESRDKANQLEEKTKLQdenlKELIEKKDHLTKELEDIKMSLQRSMSTQKALEE---DLQIATKTICQLTEEKEAQME 338

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  353 RLNsvsKAEKQLETATAEREASNATITDLksqLARAVSRAEAAERKARMEATEAEKRQiAELrDDLSSAKIEREISEEKL 432
Cdd:pfam05483 339 ELN---KAKAAHSFVVTEFEATTCSLEEL---LRTEQQRLEKNEDQLKIITMELQKKS-SEL-EEMTKFKNNKEVELEEL 410

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  433 RREIRDLKEGIEREKERARIREiELRGEQSVLESKMESLRSRAE--EVSSSATGESHAKLLRQIEVLQTQyaVASENWHG 510
Cdd:pfam05483 411 KKILAEDEKLLDEKKQFEKIAE-ELKGKEQELIFLLQAREKEIHdlEIQLTAIKTSEEHYLKEVEDLKTE--LEKEKLKN 487

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  511 IEgsLIARLTAVETERDELERREGDLR---RKAREASLKAKKVEGELENSRAVIQEIERNL--------EASKQEIQNLT 579
Cdd:pfam05483 488 IE--LTAHCDKLLLENKELTQEASDMTlelKKHQEDIINCKKQEERMLKQIENLEEKEMNLrdelesvrEEFIQKGDEVK 565

                         330       340
                  ....*....|....*....|....*..
gi 240279359  580 RKLTKAENDFLVVKQDLAKQKEAELTL 606
Cdd:pfam05483 566 CKLDKSEENARSIEYEVLKKEKQMKIL 592
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 397-626 6.44e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 6.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   397 RKARMEATEAEKRQ------IAELRDDLSSAKIEREISEE--KLRREIRDL--------KEGIEREKERARIREIELRGE 460
Cdd:TIGR02169  173 EKALEELEEVEENIerldliIDEKRQQLERLRREREKAERyqALLKEKREYegyellkeKEALERQKEAIERQLASLEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   461 QSVLESKMESLRSRAEEVsssatgeshAKLLRQIEvlqtqyavasenwHGIEGSLIARLTAVETERDELERREGDLRRKA 540
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEI---------EQLLEELN-------------KKIKDLGEEEQLRVKEKIGELEAEIASLERSI 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   541 REASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKaendflvVKQDLAKQKEAELTLIQRLEEERARWQEL 620
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDK-------LTEEYAELKEELEDLRAELEEVDKEFAET 383


                   ....*.
gi 240279359   621 ARRPSS 626
Cdd:TIGR02169  384 RDELKD 389
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 272-488 6.48e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 6.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 272 SLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKD-------------LVNAE- 337
Cdd:COG3883   34 AAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAlyrsggsvsyldvLLGSEs 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 338 -----DRVSQAEIAEQKALERLNSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEA--AERKARMEATEAEKRQ 410
Cdd:COG3883  114 fsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAqqAEQEALLAQLSAEEAA 193

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 240279359 411 IAELRDDLSSAKIEREiSEEKLRREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEVSSSATGESHA 488
Cdd:COG3883  194 AEAQLAELEAELAAAE-AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAGAAGAAAG 270
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 274-578 7.23e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 7.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  274 EKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALER 353
Cdd:TIGR04523 334 NKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQ 413

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  354 LNSV----SKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKarmeaTEAEKRQIAELRDDLSSAK-----IE 424
Cdd:TIGR04523 414 IKKLqqekELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNT-----RESLETQLKVLSRSINKIKqnleqKQ 488

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  425 REISE-----EKLRREIRDLKEGI---EREKERARIREIELRGEQSVLESKMESLRSRAEEVSSSATgeshaKLLRQIEV 496
Cdd:TIGR04523 489 KELKSkekelKKLNEEKKELEEKVkdlTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELK-----KENLEKEI 563

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  497 LQTQYAVasENWHGIEGSLIARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRA---VIQEIERNLEASKQ 573
Cdd:TIGR04523 564 DEKNKEI--EELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKeneKLSSIIKNIKSKKN 641


                  ....*
gi 240279359  574 EIQNL 578
Cdd:TIGR04523 642 KLKQE 646
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 397-615 8.11e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 8.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 397 RKARMEATEAEKRqIAELRDDLSSAKIEREISEEKLRREIRDLKEGIEREKERA--RIREIElrGEQSVLESKMESLRSR 474
Cdd:PRK05771  46 RKLRSLLTKLSEA-LDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEKIekEIKELE--EEISELENEIKELEQE 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 475 AEEVSSSATGESHAKLLRQIEVLQTQYAVASENwHGIEGSLIARLTAVETERDE----------LERREGDLRRKAREAS 544
Cdd:PRK05771 123 IERLEPWGNFDLDLSLLLGFKYVSVFVGTVPED-KLEELKLESDVENVEYISTDkgyvyvvvvvLKELSDEVEEELKKLG 201

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240279359 545 LKAKKVEgELENSRAVIQEIERNLEASKQEIQNLTRKL----TKAENDFLVVKQDLAKQKEAELTLIQRLEEERA 615
Cdd:PRK05771 202 FERLELE-EEGTPSELIREIKEELEEIEKERESLLEELkelaKKYLEELLALYEYLEIELERAEALSKFLKTDKT 275
PRK11281 PRK11281
mechanosensitive channel MscK;
244-623 8.66e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.98  E-value: 8.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  244 DALQSKLKYLAKEAAESAknaaasaeagslEKKLLekdeqIANLMEEGQKLSKTElDHRATIKKLRQSIAESAKSQAETK 323
Cdd:PRK11281   39 ADVQAQLDALNKQKLLEA------------EDKLV-----QQDLEQTLALLDKID-RQKEETEQLKQQLAQAPAKLRQAQ 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  324 KRLEKVEKDLVNaedrvsqaeiAEQKALERLnSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEaaerKARMEA 403
Cdd:PRK11281  101 AELEALKDDNDE----------ETRETLSTL-SLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPE----RAQAAL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  404 TEAEKRqIAELRDDLSSAKiereISEEKLRREIRDLkegierekerarireieLRGEQSVLESKMESLRsraeevsssat 483
Cdd:PRK11281  166 YANSQR-LQQIRNLLKGGK----VGGKALRPSQRVL-----------------LQAEQALLNAQNDLQR----------- 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  484 geshaKLLRQIEVLQTQYavasenwhgiegsliarltavETERDELerregdlrrkareaSLKAKKVEGELENSRAVIQe 563
Cdd:PRK11281  213 -----KSLEGNTQLQDLL---------------------QKQRDYL--------------TARIQRLEHQLQLLQEAIN- 251

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240279359  564 iERNLEASKQEIQNLT--RKLTKAENDFLVvkqdlAKQKEAELTLIQRLEEERARWQELARR 623
Cdd:PRK11281  252 -SKRLTLSEKTVQEAQsqDEAARIQANPLV-----AQELEINLQLSQRLLKATEKLNTLTQQ 307
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 292-450 9.13e-04

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 42.53  E-value: 9.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  292 QKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLETATAER 371
Cdd:TIGR02794  57 QQKKPAAKKEQERQKKLEQQAEEAEKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKA 136

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240279359  372 EASNAtitdlKSQLARAVSRAEAaerKARMEATEAEKRQIAELRDDLSSAKIEREISEEKLRREIRDLKEGIEREKERA 450
Cdd:TIGR02794 137 EAEAE-----RKAKEEAAKQAEE---EAKAKAAAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAEEAKAKAEAAKAKAAA 207
PTZ00121 PTZ00121
MAEBL; Provisional
 229-581 9.48e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 9.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  229 ELRWQEELHAYVERIDALQSKLKYLAKEAAESAKNAAASAEAGSL-EKKLLEKDEQIANlmEEGQKLSKTELDHRATIKK 307
Cdd:PTZ00121 1556 ELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLyEEEKKMKAEEAKK--AEEAKIKAEELKKAEEEKK 1633

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  308 lrqSIAESAKSQAETKKRLEKV----EKDLVNAEDRVSQAEIAEQKAlERLNSVSKAEKQLETATAEREASNATITDLKS 383
Cdd:PTZ00121 1634 ---KVEQLKKKEAEEKKKAEELkkaeEENKIKAAEEAKKAEEDKKKA-EEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  384 QLARAVSRAEAA-----ERKARME----ATEAEKRQIAELRDDLSSAK--IEREISEEKLRREIRDLKEGIERE--KERA 450
Cdd:PTZ00121 1710 KEAEEKKKAEELkkaeeENKIKAEeakkEAEEDKKKAEEAKKDEEEKKkiAHLKKEEEKKAEEIRKEKEAVIEEelDEED 1789

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  451 RIREIELRGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAVASE---------NWHGIEGSLIARLTA 521
Cdd:PTZ00121 1790 EKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEadafekhkfNKNNENGEDGNKEAD 1869

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 240279359  522 VETERDELERREGDLRRKAREASLKAKKVEGELENSRA-------------VIQEIERNLEASKQEIQNLTRK 581
Cdd:PTZ00121 1870 FNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMagknndiiddkldKDEYIKRDAEETREEIIKISKK 1942
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 760-856 9.69e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 9.69e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 760 ERMSTTIRRLESERAAFKDEIVRLTAQRDEARQEVVELMREVEEKRK----CDQRIQELEATVEQLDQRYQTTLEMLGEK 835
Cdd:COG1196  256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQdiarLEERRRELEERLEELEEELAELEEELEEL 335

                         90       100
                 ....*....|....*....|.
gi 240279359 836 SELVEELKADISDLKKIYREL 856
Cdd:COG1196  336 EEELEELEEELEEAEEELEEA 356
PTZ00121 PTZ00121
MAEBL; Provisional
 313-623 1.05e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 1.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  313 AESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALER-LNSVSKAE--------KQLETATAEREASNATITDLKS 383
Cdd:PTZ00121 1172 AEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERkAEEARKAEdakkaeavKKAEEAKKDAEEAKKAEEERNN 1251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  384 QLARAVSRAEAAERKARMEATEAEKRQIAelrDDLSSAKIEREISEEKLRREIRDLKEGIEREKERARIREIELRGEQSv 463
Cdd:PTZ00121 1252 EEIRKFEEARMAHFARRQAAIKAEEARKA---DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEA- 1327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  464 lESKMESLRSRAEEVSSSAtgeshakllrqiEVLQTQYAVASENWHGIEgsliARLTAVETERDELERREGDLRRKAREA 543
Cdd:PTZ00121 1328 -KKKADAAKKKAEEAKKAA------------EAAKAEAEAAADEAEAAE----EKAEAAEKKKEEAKKKADAAKKKAEEK 1390

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  544 SlKAKKVEGELENSRAVIQEIERNLEASKQ--EIQNLTRKLTKAENdflvVKQDLAKQKEAEltLIQRLEEERARWQELA 621
Cdd:PTZ00121 1391 K-KADEAKKKAEEDKKKADELKKAAAAKKKadEAKKKAEEKKKADE----AKKKAEEAKKAD--EAKKKAEEAKKAEEAK 1463


                  ..
gi 240279359  622 RR 623
Cdd:PTZ00121 1464 KK 1465
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 215-613 1.18e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.65  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   215 EEAMAQMRADHEM---------SELRWQEELHAYVERIDALQSKLKYLAKEAAESAKNAAASAEAgSLEKKLLEKDEQIA 285
Cdd:TIGR00618  232 REALQQTQQSHAYltqkreaqeEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLA-AHIKAVTQIEQQAQ 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   286 NLMEEGQ---KLSKTELDHRATIKKLRQSIAESAKSQA--------------ETKKRLEKVEKDLVNAEDRVSQAEIAEQ 348
Cdd:TIGR00618  311 RIHTELQskmRSRAKLLMKRAAHVKQQSSIEEQRRLLQtlhsqeihirdaheVATSIREISCQQHTLTQHIHTLQQQKTT 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   349 kALERLNSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEKR-QIAELRDDLSSAKIEREI 427
Cdd:TIGR00618  391 -LTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTaQCEKLEKIHLQESAQSLK 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   428 SEEKLRREIRDLKEGIEREKERARIREIELRGEQSVLEskmESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAVASEN 507
Cdd:TIGR00618  470 EREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLC---GSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEED 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   508 WHGIEGSLIARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAEN 587
Cdd:TIGR00618  547 VYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQD 626

                          410       420
                   ....*....|....*....|....*...
gi 240279359   588 DFLVVKQDLAKQKE--AELTLIQRLEEE 613
Cdd:TIGR00618  627 LQDVRLHLQQCSQElaLKLTALHALQLT 654
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 320-601 1.60e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.25  E-value: 1.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  320 AETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQL-----ETATAEREASNATITDLKSQLARAVSRAEA 394
Cdd:COG3096   839 AALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQAnlladETLADRLEELREELDAAQEAQAFIQQHGKA 918

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  395 AERKARMEAT-EAEKRQIAELRDDLSSAKIEREiseeKLRREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLRS 473
Cdd:COG3096   919 LAQLEPLVAVlQSDPEQFEQLQADYLQAKEQQR----RLKQQIFALSEVVQRRPHFSYEDAVGLLGENSDLNEKLRARLE 994

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  474 RAEEVSSSATgeshakllRQIEVLQTQYAVASENWHGIEGSLIAR---LTAVETERDELE-RREGDLRRKAREaslKAKK 549
Cdd:COG3096   995 QAEEARREAR--------EQLRQAQAQYSQYNQVLASLKSSRDAKqqtLQELEQELEELGvQADAEAEERARI---RRDE 1063

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 240279359  550 VEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKE 601
Cdd:COG3096  1064 LHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAKA 1115
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 249-565 1.67e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.27  E-value: 1.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   249 KLKYLAKEAAESAKNAAASAEagsLEKKLLEKDEQ--IANLMEEGQKLSKTELDHRATIKKLRQSIAESAKsQAETKKRL 326
Cdd:pfam02463  201 KLKEQAKKALEYYQLKEKLEL---EEEYLLYLDYLklNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLA-QVLKENKE 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   327 EKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEA 406
Cdd:pfam02463  277 EEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   407 EKRQIAELRDDLSSAKIEREISEEKLRREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEVSSSATGES 486
Cdd:pfam02463  357 EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEE 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   487 HAKLLRQIEVLQTQYAVASENWHGIEGSLIARLTAVETERDEL-----ERREGDLRRKAREASLKAKKVEGELENSRAVI 561
Cdd:pfam02463  437 ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLvklqeQLELLLSRQKLEERSQKESKARSGLKVLLALI 516


                   ....
gi 240279359   562 QEIE 565
Cdd:pfam02463  517 KDGV 520
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 345-647 1.73e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.13  E-value: 1.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   345 IAEQKALERLNSVSKAEKQLETATAEREASNATITDLKSQLaRAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIE 424
Cdd:pfam12128  227 IRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGY-KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDE 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   425 REISEEKLRREIRDLKEGIEREKERARIREiELRGEQSVLESKME-SLRSRAEEVSssatgESHAKLLRQIEVLQTQY-- 501
Cdd:pfam12128  306 LNGELSAADAAVAKDRSELEALEDQHGAFL-DADIETAAADQEQLpSWQSELENLE-----ERLKALTGKHQDVTAKYnr 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   502 ---AVASENWHGIEG---------SLIARLTAVetERDELERREGDLR-------RKAREASLKAKKVEGELE---NSRA 559
Cdd:pfam12128  380 rrsKIKEQNNRDIAGikdklakirEARDRQLAV--AEDDLQALESELReqleagkLEFNEEEYRLKSRLGELKlrlNQAT 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   560 VIQEIERNLEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERARWQELARRPSSPFLQ-EPPTGSPI 638
Cdd:pfam12128  458 ATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQlFPQAGTLL 537


                   ....*....
gi 240279359   639 TFNRKQTAG 647
Cdd:pfam12128  538 HFLRKEAPD 546
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 306-450 2.13e-03

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 41.33  E-value: 2.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 306 KKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALErlnsvskAEKQLETATAEREASNATITDLKSQL 385
Cdd:PRK09510  83 KKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAAL-------KQKQAEEAAAKAAAAAKAKAEAEAKR 155

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 240279359 386 ARAVSRAEAAERKARMEAtEAEKRQIAELRDDLSSAKIEREISEEKLRREIRDLKEGIEREKERA 450
Cdd:PRK09510 156 AAAAAKKAAAEAKKKAEA-EAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKKKAAAEAKKKA 219
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 229-619 2.23e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.96  E-value: 2.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   229 ELRWQEELHAYVERIDALQSKLKyLAKEAAESAKNAAASAEAGSLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKL 308
Cdd:TIGR00606  497 ETLKKEVKSLQNEKADLDRKLRK-LDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQL 575

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   309 RQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKA----------EKQLETATAEREASNATI 378
Cdd:TIGR00606  576 EDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgsqdeESDLERLKEEIEKSSKQR 655

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   379 TDLKSQLARAVSRAEAAERKA--------RMEATEAEKRQ-IAELRDDLSSAKIEREISE------EKLRREIRDLKEGI 443
Cdd:TIGR00606  656 AMLAGATAVYSQFITQLTDENqsccpvcqRVFQTEAELQEfISDLQSKLRLAPDKLKSTEselkkkEKRRDEMLGLAPGR 735

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   444 EREKERARIREIELRGEQSVLESKMESLRSRAEEVSS-----SATGESHAKLLRQIEVLQTQYAVASENWHGIEGsliar 518
Cdd:TIGR00606  736 QSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETllgtiMPEEESAKVCLTDVTIMERFQMELKDVERKIAQ----- 810

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359   519 lTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQE-------------------------------IERN 567
Cdd:TIGR00606  811 -QAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDqqeqiqhlksktnelkseklqigtnlqrrqqFEEQ 889

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|..
gi 240279359   568 LEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERARWQE 619
Cdd:TIGR00606  890 LVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQD 941
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
210-479 2.29e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.56  E-value: 2.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 210 STDDYEEAMAQMRADHEMSELRwQEELHAYVERIDALQSKLKYLAKEAAESAKNAAASAEAgslEKKLLEKDEQIANLME 289
Cdd:PRK02224 469 TIEEDRERVEELEAELEDLEEE-VEEVEERLERAEDLVEAEDRIERLEERREDLEELIAER---RETIEEKRERAEELRE 544

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 290 EGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAED-RVSQAEIAE-QKALERLNSVSKAEKQLETA 367
Cdd:PRK02224 545 RAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERiRTLLAAIADaEDEIERLREKREALAELNDE 624

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 368 TAEReasnatitdlksqlaravsRAEAAERKARMEATEAEKRqIAELRDDLSSAKIEREISEEKLR--REIRD--LKE-- 441
Cdd:PRK02224 625 RRER-------------------LAEKRERKRELEAEFDEAR-IEEAREDKERAEEYLEQVEEKLDelREERDdlQAEig 684

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 240279359 442 GIEREKERARireiELRGEQSVLESKMESLRSRAEEVS 479
Cdd:PRK02224 685 AVENELEELE----ELRERREALENRVEALEALYDEAE 718
PspA COG1842
Phage shock protein A [Transcription, Signal transduction mechanisms];
302-476 2.30e-03

Phage shock protein A [Transcription, Signal transduction mechanisms];


Pssm-ID: 441447 [Multi-domain]  Cd Length: 217  Bit Score: 40.19  E-value: 2.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 302 RATIKKLRQSIAESAKSQAETKKRLEKVEKDlvnAEDRVSQAEIA-----EQKALERLNSVSKAEKQLETATAEREASNA 376
Cdd:COG1842   36 EEDLVEARQALAQVIANQKRLERQLEELEAE---AEKWEEKARLAlekgrEDLAREALERKAELEAQAEALEAQLAQLEE 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 377 TITDLKSQLARA--------------VSRAEAAErkarmeATEAEKRQIAELRDDLSSAKIEReiseeklrreirdLKEG 442
Cdd:COG1842  113 QVEKLKEALRQLeskleelkakkdtlKARAKAAK------AQEKVNEALSGIDSDDATSALER-------------MEEK 173

                        170       180       190
                 ....*....|....*....|....*....|....
gi 240279359 443 IEREKERARIREiELRGEQSvLESKMESLRSRAE 476
Cdd:COG1842  174 IEEMEARAEAAA-ELAAGDS-LDDELAELEADSE 205
PspA_IM30 pfam04012
PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent ...
 300-465 2.36e-03

PspA/IM30 family; This family includes PspA a protein that suppresses sigma54-dependent transcription. The PspA protein, a negative regulator of the Escherichia coli phage shock psp operon, is produced when virulence factors are exported through secretins in many Gram-negative pathogenic bacteria and its homolog in plants, VIPP1, plays a critical role in thylakoid biogenesis, essential for photosynthesis. Activation of transcription by the enhancer-dependent bacterial sigma(54) containing RNA polymerase occurs through ATP hydrolysis-driven protein conformational changes enabled by activator proteins that belong to the large AAA(+) mechanochemical protein family. It has been shown that PspA directly and specifically acts upon and binds to the AAA(+) domain of the PspF transcription activator.


Pssm-ID: 461130 [Multi-domain]  Cd Length: 215  Bit Score: 40.43  E-value: 2.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  300 DHRATIKKLRQSIAESAKSQAETKKRLEKVEKDlvnAEDRVSQAEIA-----EQKALERLNSVSKAEKQLETATAEREAS 374
Cdd:pfam04012  33 DMQSELVKARQALAQTIARQKQLERRLEQQTEQ---AKKLEEKAQAAltkgnEELAREALAEKKSLEKQAEALETQLAQQ 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  375 NATITDLKSQLARAVSRAEAAERKARMEATEaEKRQIAELRDDLSSAKIEREISEEKLRReirdLKEGIEREKERARIRE 454
Cdd:pfam04012 110 RSAVEQLRKQLAALETKIQQLKAKKNLLKAR-LKAAKAQEAVQTSLGSLSTSSATDSFER----IEEKIEEREARADAAA 184

                         170
                  ....*....|.
gi 240279359  455 iELRGEQSVLE 465
Cdd:pfam04012 185 -ELASAVDLDA 194
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 291-399 2.46e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 41.74  E-value: 2.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  291 GQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLvnaEDRVSQAEIAEQKALERLNSVSKAEKQLETAT-- 368
Cdd:NF012221 1670 GKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQDI---DDAKADAEKRKDDALAKQNEAQQAESDANAAAnd 1746

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 240279359  369 ----AEREASNAtitdlKSQLARAVSRAEAAERKA 399
Cdd:NF012221 1747 aqsrGEQDASAA-----ENKANQAQADAKGAKQDE 1776
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 272-613 2.62e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.54  E-value: 2.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  272 SLEKKLLEKDEQIANLMEEgqklskteldhratIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKAL 351
Cdd:TIGR04523 128 KLEKQKKENKKNIDKFLTE--------------IKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIK 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  352 ERLNSVSKAEKQLETATAEREASNATITDLKSQlaravsraeaaeRKARMEATEAEKRQIAELRDDLSSAKIEREISEEK 431
Cdd:TIGR04523 194 NKLLKLELLLSNLKKKIQKNKSLESQISELKKQ------------NNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDE 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  432 LRREIRDLKEGIeREKERARIREIELRGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYavaSENWHGI 511
Cdd:TIGR04523 262 QNKIKKQLSEKQ-KELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQI---SQNNKII 337

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  512 EgSLIARLTAVETERDELERREGDLRRkareaslkakkvegELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLV 591
Cdd:TIGR04523 338 S-QLNEQISQLKKELTNSESENSEKQR--------------ELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQN 402

                         330       340
                  ....*....|....*....|..
gi 240279359  592 VKQdLAKQKEAEltlIQRLEEE 613
Cdd:TIGR04523 403 QEK-LNQQKDEQ---IKKLQQE 420
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 513-623 2.72e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.29  E-value: 2.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 513 GSLIARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASK---------QEIQNLTRKLT 583
Cdd:COG1579   27 KELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRnnkeyealqKEIESLKRRIS 106

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 240279359 584 KAENDFLVVKQDLAKQKEAELTLIQRLEEERARWQELARR 623
Cdd:COG1579  107 DLEDEILELMERIEELEEELAELEAELAELEAELEEKKAE 146
PHA01972 PHA01972
structural protein
 273-451 3.21e-03

structural protein


Pssm-ID: 222842  Cd Length: 828  Bit Score: 41.06  E-value: 3.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 273 LEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKkRLEKVEKDLVNAED---------RVSQA 343
Cdd:PHA01972   1 MPQKCVEAVAQAAGRQLTADEIKGIEDRIKEAMRSVARKDPKGWKEESIAK-RFYKTDADLARQELvhdaikkkkRVALA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 344 EIAEQKALERLNSVSKAEKQLET------ATAEREASNATITDLKSQLARAVSRAEAAE-RKARMEATEAEKRQIA--EL 414
Cdd:PHA01972  80 IAKQAEATKKINEVLTADKDPAAallgmlSRDPNEEAKFLSVEQRINATRDVSKAKISDfMAALDPTTRQIFAGIAtgER 159

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 240279359 415 RDDLSSAKIEREISeeklrREIRDLKEGIEREKERAR 451
Cdd:PHA01972 160 RFDKAQQRLLDDIV-----HELYGRQTGNADAKKAAK 191
HOOK pfam05622
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...
 275-588 3.31e-03

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.


Pssm-ID: 461694 [Multi-domain]  Cd Length: 528  Bit Score: 40.83  E-value: 3.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  275 KKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVE--KD----LVNAEDRVSQAEIAEQ 348
Cdd:pfam05622  59 KKYLLLQKQLEQLQEENFRLETARDDYRIKCEELEKEVLELQHRNEELTSLAEEAQalKDemdiLRESSDKVKKLEATVE 138

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  349 ---KALERLNSVSKAEKQLEtataEReasNATITDLKSQLARAVSRAEAAERKarmeaTEAEKRQIAELRDDLSsakiER 425
Cdd:pfam05622 139 tykKKLEDLGDLRRQVKLLE----ER---NAEYMQRTLQLEEELKKANALRGQ-----LETYKRQVQELHGKLS----EE 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  426 EISEEKLRREIRDLKEGIE---REKERARI-----REI--ELRGEQSvleSKMESLRSRAEEVSSSATGESHAKLLRQIE 495
Cdd:pfam05622 203 SKKADKLEFEYKKLEEKLEalqKEKERLIIerdtlRETneELRCAQL---QQAELSQADALLSPSSDPGDNLAAEIMPAE 279

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  496 VLQTQYAVASEN---WHGIEGSLIARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEAS- 571
Cdd:pfam05622 280 IREKLIRLQHENkmlRLGQEGSYRERLTELQQLLEDANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSs 359

                         330
                  ....*....|....*....
gi 240279359  572 --KQEIQNLTRKLTKAEND 588
Cdd:pfam05622 360 llKQKLEEHLEKLHEAQSE 378
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
766-858 3.38e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 3.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  766 IRRLESERAAFKDEIVRLTAQRDEARQEVVELMREVEEKRkcDQRIQELEATVEQLDQRYQTTLEMLGEKSELVEELKAD 845
Cdd:COG4913   297 LEELRAELARLEAELERLEARLDALREELDELEAQIRGNG--GDRLEQLEREIERLERELEERERRRARLEALLAALGLP 374

                          90
                  ....*....|...
gi 240279359  846 ISDLKKIYRELVD 858
Cdd:COG4913   375 LPASAEEFAALRA 387
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
273-489 3.41e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.20  E-value: 3.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 273 LEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRqsiaESAKSQAETKKRLEKVE-KDLVNAEDRVSQAEIAEQKAL 351
Cdd:PRK03918 530 LKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLD----ELEEELAELLKELEELGfESVEELEERLKELEPFYNEYL 605

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 352 ERLNSVSKAE---KQLETATAEREASNATITDLKSQLARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREIS 428
Cdd:PRK03918 606 ELKDAEKELEreeKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEEL 685

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 240279359 429 EEKLRREIRDLKEGIEREKERARIREiELRGEQSVLEsKMESLRSRAEEVSSSATGESHAK 489
Cdd:PRK03918 686 EKRREEIKKTLEKLKEELEEREKAKK-ELEKLEKALE-RVEELREKVKKYKALLKERALSK 744
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
770-856 3.92e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.00  E-value: 3.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 770 ESERAAFKDEIVRLTAQRDEARQEVVELMREVEEKrkcDQRIQELEATVEQLDQRYQTTLemlgEKSELVEELKADISDL 849
Cdd:COG2433  405 ERELTEEEEEIRRLEEQVERLEAEVEELEAELEEK---DERIERLERELSEARSEERREI----RKDREISRLDREIERL 477


                 ....*..
gi 240279359 850 KKIYREL 856
Cdd:COG2433  478 ERELEEE 484
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 241-462 4.14e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 40.81  E-value: 4.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  241 ERIDALQSKLKYLAKEAAESAKNAAASAEAGSLEKKLLEKDEQIANLMEEGQKLSKTEldhraTIKKLRQSIAEsAKSQA 320
Cdd:PRK10929   45 EIVEALQSALNWLEERKGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSVPPNM-----STDALEQEILQ-VSSQL 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  321 ETKKRLEKVEKDLVNA-EDRVSQaeIAEQKalerlnsvSKAEKQLETATAEREASNATITDLkSQLARAVSRAEAAERKA 399
Cdd:PRK10929  119 LEKSRQAQQEQDRAREiSDSLSQ--LPQQQ--------TEARRQLNEIERRLQTLGTPNTPL-AQAQLTALQAESAALKA 187

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  400 RMEATE-----AEKRQ-IAELRDDLSSAKIER-EISEEKLRREIRDLKegiEREKERArIREIELRGEQS 462
Cdd:PRK10929  188 LVDELElaqlsANNRQeLARLRSELAKKRSQQlDAYLQALRNQLNSQR---QREAERA-LESTELLAEQS 253
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 346-554 4.54e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.52  E-value: 4.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 346 AEQKALERLNSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAErkarmEATEAEKRQIAELRDDLSSAKIER 425
Cdd:COG1579    1 AMPEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAK-----TELEDLEKEIKRLELEIEEVEARI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 426 EISEEKLrREIRDLKE--GIEREKErarireiELRGEQSVLESKMeslrsraeevsssatgeshAKLLRQIEVLQTQYAV 503
Cdd:COG1579   76 KKYEEQL-GNVRNNKEyeALQKEIE-------SLKRRISDLEDEI-------------------LELMERIEELEEELAE 128

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 240279359 504 ASENWHGIEGSLIARLTAVETERDELERREGDLRRKAREAslkAKKVEGEL 554
Cdd:COG1579  129 LEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL---AAKIPPEL 176
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
492-631 4.82e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 4.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  492 RQIEVLQTQYAVASENWHGIEgsliARLTAVETERDELERREGDLRR--KAREASLKAKKVEGELENSRAVIQEIERN-- 567
Cdd:COG4913   610 AKLAALEAELAELEEELAEAE----ERLEALEAELDALQERREALQRlaEYSWDEIDVASAEREIAELEAELERLDASsd 685

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 240279359  568 -LEASKQEIQNLTRKLTKAENDFLVVKQD---LAKQKEAELTLIQRLEEERARWQELARRPSSPFLQE 631
Cdd:COG4913   686 dLAALEEQLEELEAELEELEEELDELKGEigrLEKELEQAEEELDELQDRLEAAEDLARLELRALLEE 753
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
272-594 4.88e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.27  E-value: 4.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 272 SLEKKLLEKDEQIANLMEEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKAL 351
Cdd:COG4372   49 QLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLE 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 352 ERLNSVSKAEKQLETATAEREasnATITDLKSQLARAVSRAEAAERKARMEATEAEKRQIAELRDDLSSAKIEREISEEK 431
Cdd:COG4372  129 QQRKQLEAQIAELQSEIAERE---EELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEA 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 432 LRREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEVSSSATGESHAKLLRQIEVLQTQYAVasENWHGI 511
Cdd:COG4372  206 EKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEE--LEIAAL 283

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 512 EGSLIARLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLV 591
Cdd:COG4372  284 ELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKGA 363


                 ...
gi 240279359 592 VKQ 594
Cdd:COG4372  364 EAG 366
Tropomyosin pfam00261
Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 ...
 312-439 5.17e-03

Tropomyosin; Tropomyosin is an alpha-helical protein that forms a coiled-coil structure of 2 parallel helices containing 2 sets of 7 alternating actin binding sites. The protein is best known for its role in regulating the interaction between actin and myosin in muscle contraction, but is also involved in the organization and dynamics of the cytoskeleton in non-muscle cells. There are multiple cell-specific isoforms, expressed by alternative promoters and alternative RNA processing of at least four genes. Muscle isoforms of tropomyosin are characterized by having 284 amino acid residues and a highly conserved N-terminal region, whereas non-muscle forms are generally smaller and are heterogeneous in their N-terminal region.


Pssm-ID: 459736 [Multi-domain]  Cd Length: 235  Bit Score: 39.63  E-value: 5.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  312 IAESA-KSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLNSVSKAEKQLET---ATAEREASNA-TITDLKSQLA 386
Cdd:pfam00261 107 IAEEAdRKYEEVARKLVVVEGDLERAEERAELAESKIVELEEELKVVGNNLKSLEAseeKASEREDKYEeQIRFLTEKLK 186

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 240279359  387 RAVSRAEAAERKA-RMEateaekRQIAELRDDLSSAKIEREISEEKLRREIRDL 439
Cdd:pfam00261 187 EAETRAEFAERSVqKLE------KEVDRLEDELEAEKEKYKAISEELDQTLAEL 234
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 273-542 5.30e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 40.38  E-value: 5.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 273 LEKKLLEKDEQIANL---MEEGQKLSK--TELDHR----ATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQA 343
Cdd:NF033838 130 FKKDTLEPGKKVAEAtkkVEEAEKKAKdqKEEDRRnyptNTYKTLELEIAESDVEVKKAELELVKEEAKEPRDEEKIKQA 209

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 344 EI---AEQKALERLNSVSKAEKQletatAEREASNATITDLKSQLARAVSRAEAAERKARME-------ATEAEKRQIAE 413
Cdd:NF033838 210 KAkveSKKAEATRLEKIKTDREK-----AEEEAKRRADAKLKEAVEKNVATSEQDKPKRRAKrgvlgepATPDKKENDAK 284

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 414 LRDDL--------SSAKIEREISE-----EKLRREIRDLKEGIEREKERARIREIELRGEQSVLESKMESLRSRAEEVSS 480
Cdd:NF033838 285 SSDSSvgeetlpsPSLKPEKKVAEaekkvEEAKKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKEAELELVKEEAKE 364

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240279359 481 SATGEshakllrqiEVLQTQYAVASENwhgiegsliARLTAVETERDELERREGDLRRKARE 542
Cdd:NF033838 365 PRNEE---------KIKQAKAKVESKK---------AEATRLEKIKTDRKKAEEEAKRKAAE 408
ATP-synt_Fo_b cd06503
F-type ATP synthase, membrane subunit b; Membrane subunit b is a component of the Fo complex ...
 323-439 5.82e-03

F-type ATP synthase, membrane subunit b; Membrane subunit b is a component of the Fo complex of FoF1-ATP synthase. The F-type ATP synthases (FoF1-ATPase) consist of two structural domains: the F1 (assembly factor one) complex containing the soluble catalytic core, and the Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F1 is composed of alpha (or A), beta (B), gamma (C), delta (D) and epsilon (E) subunits with a stoichiometry of 3:3:1:1:1, while Fo consists of the three subunits a, b, and c (1:2:10-14). An oligomeric ring of 10-14 c subunits (c-ring) make up the Fo rotor. The flux of protons through the ATPase channel (Fo) drives the rotation of the c-ring, which in turn is coupled to the rotation of the F1 complex gamma subunit rotor due to the permanent binding between the gamma and epsilon subunits of F1 and the c-ring of Fo. The F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. The F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis. This group also includes F-ATP synthase that has also been found in the archaea Candidatus Methanoperedens.


Pssm-ID: 349951 [Multi-domain]  Cd Length: 132  Bit Score: 37.80  E-value: 5.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 323 KKRLEKVEKDLVNAEDRVSQAEIAEQkalerlnsvsKAEKQLETATAEREAsnatitdlksQLARAVSRAEAAERKARME 402
Cdd:cd06503   29 DEREEKIAESLEEAEKAKEEAEELLA----------EYEEKLAEARAEAQE----------IIEEARKEAEKIKEEILAE 88

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 240279359 403 ATEAEKRQIAELRDDLSSakiEREISEEKLRREIRDL 439
Cdd:cd06503   89 AKEEAERILEQAKAEIEQ---EKEKALAELRKEVADL 122
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 518-613 6.11e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.14  E-value: 6.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 518 RLTAVETERDELERREGDLRRKAREASLKAKKVEGELENSRAVIQEIERNLEASKQEIQNLTRKLTKAENDFLVVK---- 593
Cdd:COG1579   11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRnnke 90

                         90       100
                 ....*....|....*....|.
gi 240279359 594 -QDLAKQKEAELTLIQRLEEE 613
Cdd:COG1579   91 yEALQKEIESLKRRISDLEDE 111
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 410-759 6.75e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 39.81  E-value: 6.75e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 410 QIAELRDDLSSAKIEREISEEKLRReirdlkegIEREKERARIREIELRGEQSVLESKMESLRSRAEEVSssatgeshAK 489
Cdd:COG3883   17 QIQAKQKELSELQAELEAAQAELDA--------LQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAE--------AE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 490 LLRQIEVLQTQYAVASENwhGIEGSLIARLTAVETERDELERRE--GDLRRKAREASLKAKKVEGELENSRAVIQEIERN 567
Cdd:COG3883   81 IEERREELGERARALYRS--GGSVSYLDVLLGSESFSDFLDRLSalSKIADADADLLEELKADKAELEAKKAELEAKLAE 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 568 LEASKQEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRLEEERARWQELARRPSSPFLQEPPTGSPITFNRKQTAG 647
Cdd:COG3883  159 LEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 648 PDPTRPMSDRALSRRSSSIPPALFSELTTPPYQNHFSPTNSNPQQPRITPSHEFSGDLTHAQTYEPEEYFNGMSTPVTPS 727
Cdd:COG3883  239 AAAAAASAAGAGAAGAAGAAAGSAGAAGAAAGAAGAGAAAASAAGGGAGGAGGGGGGGGAASGGSGGGSGGAGGVGSGGG 318

                        330       340       350
                 ....*....|....*....|....*....|..
gi 240279359 728 AQGTHTLTHHSRGVNDIISVSTVAAGPSVQVV 759
Cdd:COG3883  319 AGAVVGGASAGGGGGSGGGGGSSGGGSGGGGG 350
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
425-619 7.13e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.14  E-value: 7.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 425 REISEEKLRREIRDLkegierEKERARIREIELRgEQSVLESKMESLRSRAEEvsssatgesHAKLLRQIEVLQTQYAva 504
Cdd:COG4717   44 RAMLLERLEKEADEL------FKPQGRKPELNLK-ELKELEEELKEAEEKEEE---------YAELQEELEELEEELE-- 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 505 senwhgiegSLIARLTAVETERDELERREGDLRRKAREASLKAKKVEG-----ELENSRAVIQEIERNLEASKQEIQNLT 579
Cdd:COG4717  106 ---------ELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELperleELEERLEELRELEEELEELEAELAELQ 176

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 240279359 580 RKLTKAENDFLVVK----QDLAKQKEAELTLIQRLEEERARWQE 619
Cdd:COG4717  177 EELEELLEQLSLATeeelQDLAEELEELQQRLAELEEELEEAQE 220
PTZ00491 PTZ00491
major vault protein; Provisional
 301-465 7.72e-03

major vault protein; Provisional


Pssm-ID: 240439 [Multi-domain]  Cd Length: 850  Bit Score: 40.00  E-value: 7.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 301 HRATIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAEDRVSQAEIAEQKALERLN-SVSKAekqLETATAEREASNATIT 379
Cdd:PTZ00491 596 HKNSAKIIRQAVFGSNDETGEVRDSLRFPANNLVITNVDVQSVEPVDERTRDSLQkSVQLA---IEITTKSQEAAARHQA 672

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 380 DLKSQLARA-------VSRAEAAERK-------ARMEATEAEKRQIAELRDDLSSAKIE--REISEEKLRREIRDLKEGI 443
Cdd:PTZ00491 673 ELLEQEARGrlerqkmHDKAKAEEQRtkllelqAESAAVESSGQSRAEALAEAEARLIEaeAEVEQAELRAKALRIEAEA 752

                        170       180
                 ....*....|....*....|..
gi 240279359 444 EREKERARiREIELRGEQSVLE 465
Cdd:PTZ00491 753 ELEKLRKR-QELELEYEQAQNE 773
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 272-609 8.07e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.00  E-value: 8.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  272 SLEKKLLEKDEQIANLMEEgqklskteldhratIKKLRQSIAESAKSQAETKKRLEKVEKDLVNAedrVSQAEIAEQKAL 351
Cdd:TIGR04523  58 NLDKNLNKDEEKINNSNNK--------------IKILEQQIKDLNDKLKKNKDKINKLNSDLSKI---NSEIKNDKEQKN 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  352 ERLNSVSKAEKQLETATAEREASNATITDLKSQLarAVSRAEAAERKARMEATEAEK----RQIAELRDDLSSAKIEREI 427
Cdd:TIGR04523 121 KLEVELNKLEKQKKENKKNIDKFLTEIKKKEKEL--EKLNNKYNDLKKQKEELENELnlleKEKLNIQKNIDKIKNKLLK 198

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  428 SEEKLrreiRDLKEGIEREKErARIREIELRGEQSVLESKMESLRSRAEEVSS---------SATGESHAKLLRQIEVLQ 498
Cdd:TIGR04523 199 LELLL----SNLKKKIQKNKS-LESQISELKKQNNQLKDNIEKKQQEINEKTTeisntqtqlNQLKDEQNKIKKQLSEKQ 273

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  499 TQyavaSENWHGIEGSLIARLTAVETERDELER-REGDLRRKAREaslKAKKVEGELENSRAVIQEIERNLEASKQEIQN 577
Cdd:TIGR04523 274 KE----LEQNNKKIKELEKQLNQLKSEISDLNNqKEQDWNKELKS---ELKNQEKKLEEIQNQISQNNKIISQLNEQISQ 346

                         330       340       350
                  ....*....|....*....|....*....|..
gi 240279359  578 LTRKLTKAENDFLVVKQDLaKQKEAELTLIQR 609
Cdd:TIGR04523 347 LKKELTNSESENSEKQREL-EEKQNEIEKLKK 377
PspA COG1842
Phage shock protein A [Transcription, Signal transduction mechanisms];
336-531 8.29e-03

Phage shock protein A [Transcription, Signal transduction mechanisms];


Pssm-ID: 441447 [Multi-domain]  Cd Length: 217  Bit Score: 38.65  E-value: 8.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 336 AEDRVsqaEIAEQKALERLNSVSKAEKQLETATAEREASNATITDLKSQLARAVSRAEAAERKARME-ATEA--EKRQIA 412
Cdd:COG1842   21 AEDPE---KMLDQAIRDMEEDLVEARQALAQVIANQKRLERQLEELEAEAEKWEEKARLALEKGREDlAREAleRKAELE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 413 ELRDDLSSAKIEREISEEKLRREIRDLKEGIerekERARIREIELRGEQSVLESKmESLRSRAEEVSSSATGESHAKLLR 492
Cdd:COG1842   98 AQAEALEAQLAQLEEQVEKLKEALRQLESKL----EELKAKKDTLKARAKAAKAQ-EKVNEALSGIDSDDATSALERMEE 172

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 240279359 493 QIEVLQTQYAVASEnwHGIEGSLIARLTAVETE---RDELER 531
Cdd:COG1842  173 KIEEMEARAEAAAE--LAAGDSLDDELAELEADsevEDELAA 212
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
766-856 8.70e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 39.66  E-value: 8.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 766 IRRLESERAAFKDEIVRLTAQRDEARQEVVELMREVEEKRKCDQRIQELEATVEQLDQRYQTTLEMLGEKSELVEELKAD 845
Cdd:PRK03918 195 IKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKE 274

                         90
                 ....*....|.
gi 240279359 846 ISDLKKIYREL 856
Cdd:PRK03918 275 IEELEEKVKEL 285
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 289-610 8.79e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 39.94  E-value: 8.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  289 EEGQKLSKTELDHRATIKKLRQSIAESAKSQAETKKRLEK-------VEKDLVNAEDR-------VSQAEIAE--QKALE 352
Cdd:COG3096   278 NERRELSERALELRRELFGARRQLAEEQYRLVEMARELEElsaresdLEQDYQAASDHlnlvqtaLRQQEKIEryQEDLE 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  353 RLNS--------VSKAEKQLETATAEREASNATITDLKSQLA--------------------RAVSRAEAAERKARMEAT 404
Cdd:COG3096   358 ELTErleeqeevVEEAAEQLAEAEARLEAAEEEVDSLKSQLAdyqqaldvqqtraiqyqqavQALEKARALCGLPDLTPE 437

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  405 EAEKRQiAELRDDLSSAKIEREISEEKL------RRE-------IRDLKEGIEREKERARIREIELRG-EQSVLESKMES 470
Cdd:COG3096   438 NAEDYL-AAFRAKEQQATEEVLELEQKLsvadaaRRQfekayelVCKIAGEVERSQAWQTARELLRRYrSQQALAQRLQQ 516

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  471 LRSRAEEVsssatgESHAKLLRQIEVLQTQYAVASenwhgieGSLIARLTAVETERDELERREGDLRRKAREASLKAKKV 550
Cdd:COG3096   517 LRAQLAEL------EQRLRQQQNAERLLEEFCQRI-------GQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSEL 583

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359  551 EGELENSRAVIQEIERN----------LE----------ASKQEIQNLTRKLTKAENDFLVVKQDLAKQKEAELTLIQRL 610
Cdd:COG3096   584 RQQLEQLRARIKELAARapawlaaqdaLErlreqsgealADSQEVTAAMQQLLEREREATVERDELAARKQALESQIERL 663
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 760-851 9.78e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 39.53  E-value: 9.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240279359 760 ERMSTTIRRLESERAAFKDEIVRLTAQRDEARQEVVELMREVEEKRkcdQRIQELEATVEQLDQRYQTTLEMLGEKSELV 839
Cdd:COG1196  242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ---AEEYELLAELARLEQDIARLEERRRELEERL 318

                         90
                 ....*....|..
gi 240279359 840 EELKADISDLKK 851
Cdd:COG1196  319 EELEEELAELEE 330
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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