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Conserved domains on  [gi|239605743|gb|EEQ82769|]
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hypothetical protein NCER_100460 [Vairimorpha ceranae BRL01]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DBF4 super family cl34887
Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, ...
 1-108 2.12e-19

Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, and repair / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5067:

Pssm-ID: 227399 [Multi-domain]  Cd Length: 468  Bit Score: 83.84  E-value: 2.12e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239605743   1 MKNYKVFKNKYILIEDIKGTHQPFHKEYT--KPPQLSLNSKPLGCPFQENKKFKPS---SKKRGPKSGFCEVCYNKFTDY 75
Cdd:COG5067   77 MKNALVPKKPYILIEDESNKYQKFLKEYAssEKPKLHLDSRTYCCAFPAFKFYKDNksgKRKHRVKEGFCELGAVVFTFF 156

                         90       100       110
                 ....*....|....*....|....*....|...
gi 239605743  76 DLHVREYEHREFARDSNNYKKIDHFISTTKFSS 108
Cdd:COG5067  157 EEHVTHFITRRFAKDNSNYKKLDVLISAKAFNM 189
 
Name Accession Description Interval E-value
DBF4 COG5067
Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, ...
 1-108 2.12e-19

Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, and repair / Cell division and chromosome partitioning];


Pssm-ID: 227399 [Multi-domain]  Cd Length: 468  Bit Score: 83.84  E-value: 2.12e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239605743   1 MKNYKVFKNKYILIEDIKGTHQPFHKEYT--KPPQLSLNSKPLGCPFQENKKFKPS---SKKRGPKSGFCEVCYNKFTDY 75
Cdd:COG5067   77 MKNALVPKKPYILIEDESNKYQKFLKEYAssEKPKLHLDSRTYCCAFPAFKFYKDNksgKRKHRVKEGFCELGAVVFTFF 156

                         90       100       110
                 ....*....|....*....|....*....|...
gi 239605743  76 DLHVREYEHREFARDSNNYKKIDHFISTTKFSS 108
Cdd:COG5067  157 EEHVTHFITRRFAKDNSNYKKLDVLISAKAFNM 189
zf-DBF pfam07535
DBF zinc finger; This domain is predicted to bind metal ions and is often found associated ...
 63-103 3.55e-14

DBF zinc finger; This domain is predicted to bind metal ions and is often found associated with pfam00533 and pfam02178. It was first identified in the Drosophila chiffon gene product, and is associated with initiation of DNA replication.


Pssm-ID: 462197  Cd Length: 42  Bit Score: 62.90  E-value: 3.55e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 239605743   63 GFCEVCYNKFTDYDLHVREYEHREFARDSNNYKKIDHFIST 103
Cdd:pfam07535   1 GYCENCRVKYEDLEEHIVSEKHRKFAENDSNFKELDELISK 41
ZnF_DBF smart00586
Zinc finger in DBF-like proteins;
60-106 8.29e-08

Zinc finger in DBF-like proteins;


Pssm-ID: 128854 [Multi-domain]  Cd Length: 49  Bit Score: 46.32  E-value: 8.29e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 239605743    60 PKSGFCEVCYNKFTDYDLHVREYEHREFARDSNNYKKIDHFISTTKF 106
Cdd:smart00586   3 KKPGYCENCREKYDDLETHLLSEKHRRFAENNDNFQALDDLISQLRR 49
 
Name Accession Description Interval E-value
DBF4 COG5067
Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, ...
 1-108 2.12e-19

Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, and repair / Cell division and chromosome partitioning];


Pssm-ID: 227399 [Multi-domain]  Cd Length: 468  Bit Score: 83.84  E-value: 2.12e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 239605743   1 MKNYKVFKNKYILIEDIKGTHQPFHKEYT--KPPQLSLNSKPLGCPFQENKKFKPS---SKKRGPKSGFCEVCYNKFTDY 75
Cdd:COG5067   77 MKNALVPKKPYILIEDESNKYQKFLKEYAssEKPKLHLDSRTYCCAFPAFKFYKDNksgKRKHRVKEGFCELGAVVFTFF 156

                         90       100       110
                 ....*....|....*....|....*....|...
gi 239605743  76 DLHVREYEHREFARDSNNYKKIDHFISTTKFSS 108
Cdd:COG5067  157 EEHVTHFITRRFAKDNSNYKKLDVLISAKAFNM 189
zf-DBF pfam07535
DBF zinc finger; This domain is predicted to bind metal ions and is often found associated ...
 63-103 3.55e-14

DBF zinc finger; This domain is predicted to bind metal ions and is often found associated with pfam00533 and pfam02178. It was first identified in the Drosophila chiffon gene product, and is associated with initiation of DNA replication.


Pssm-ID: 462197  Cd Length: 42  Bit Score: 62.90  E-value: 3.55e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 239605743   63 GFCEVCYNKFTDYDLHVREYEHREFARDSNNYKKIDHFIST 103
Cdd:pfam07535   1 GYCENCRVKYEDLEEHIVSEKHRKFAENDSNFKELDELISK 41
ZnF_DBF smart00586
Zinc finger in DBF-like proteins;
60-106 8.29e-08

Zinc finger in DBF-like proteins;


Pssm-ID: 128854 [Multi-domain]  Cd Length: 49  Bit Score: 46.32  E-value: 8.29e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*..
gi 239605743    60 PKSGFCEVCYNKFTDYDLHVREYEHREFARDSNNYKKIDHFISTTKF 106
Cdd:smart00586   3 KKPGYCENCREKYDDLETHLLSEKHRRFAENNDNFQALDDLISQLRR 49
DBF4 COG5067
Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, ...
 57-106 2.52e-05

Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, and repair / Cell division and chromosome partitioning];


Pssm-ID: 227399 [Multi-domain]  Cd Length: 468  Bit Score: 43.40  E-value: 2.52e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 239605743  57 KRGPKSGFCEVCYNKFTDYDLHVREYEHREFARDSNNYKKIDHFISTTKF 106
Cdd:COG5067  417 KKETKKGYCENCREKYESLEQHIVSEKHRRFAENDLNFEALDSLFELLRR 466
Dfp1_Him1_M pfam08630
Dfp1/Him1, central region; This is the middle regions described by Ogino et al. This region, ...
 2-47 8.52e-04

Dfp1/Him1, central region; This is the middle regions described by Ogino et al. This region, together with the C-terminal zinc finger (pfam07535) is essential for the mitotic and kinase activation functions of Dfp1/Him1.


Pssm-ID: 430116  Cd Length: 128  Bit Score: 37.56  E-value: 8.52e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 239605743    2 KNYKVFKNKYILIEDIKGTHQPFH-KEYTKP---------PQLSLNskPLG-CPFQE 47
Cdd:pfam08630  74 DDLHYFKGPYVYVYDLDQKTRPIMvREYPKVapkekdgpwPQFRST--TDGrCPFIE 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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