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Conserved domains on  [gi|163776656|gb|EDQ90275|]
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predicted protein [Monosiga brevicollis MX1]

Protein Classification

ESCRT-I complex subunit VPS28( domain architecture ID 10512640)

ESCRT-I complex subunit VPS28 (vacuolar protein sorting-associated protein 28) is a component of the endosomal sorting complex required for transport I, which is a regulator of vesicular trafficking processes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
VPS28 pfam03997
VPS28 protein;
35-219 9.23e-79

VPS28 protein;


:

Pssm-ID: 427639  Cd Length: 187  Bit Score: 234.33  E-value: 9.23e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163776656   35 LAAVYEILLTLEHIERAYVHDNIGEAEYTETCKKLLTRFKACRNLLPSDVANDIPAFAATYRLECPAALQRIRVGVPATT 114
Cdd:pfam03997   1 LAELYSIIVTLEHLEKAYIKDSITAKEYTSTCSRLLAQYKTILDELVKDEFPDLEEFMKKYRLDCPAALERLREGVPATV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163776656  115 EFGSGPSADHVKRSRHVMAATEHFISITDTFSMDIGDVDKLHNEVSGLMDQLNKLDDLSPDHISKRNVLKWLEVLSAMKA 194
Cdd:pfam03997  81 EHSASSSADGGNSAKLVAEATQNFITLMDALKLNYRAKDQLHPLLSDLLQSLNKLSLLPPDFEGKSKLVKWLIKLNNMKA 160

                         170       180
                  ....*....|....*....|....*
gi 163776656  195 TDALSPEQIREALMDFDMAYDAYKR 219
Cdd:pfam03997 161 SDELSEEQARQLLFDLESAYNAFYR 185
 
Name Accession Description Interval E-value
VPS28 pfam03997
VPS28 protein;
35-219 9.23e-79

VPS28 protein;


Pssm-ID: 427639  Cd Length: 187  Bit Score: 234.33  E-value: 9.23e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163776656   35 LAAVYEILLTLEHIERAYVHDNIGEAEYTETCKKLLTRFKACRNLLPSDVANDIPAFAATYRLECPAALQRIRVGVPATT 114
Cdd:pfam03997   1 LAELYSIIVTLEHLEKAYIKDSITAKEYTSTCSRLLAQYKTILDELVKDEFPDLEEFMKKYRLDCPAALERLREGVPATV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163776656  115 EFGSGPSADHVKRSRHVMAATEHFISITDTFSMDIGDVDKLHNEVSGLMDQLNKLDDLSPDHISKRNVLKWLEVLSAMKA 194
Cdd:pfam03997  81 EHSASSSADGGNSAKLVAEATQNFITLMDALKLNYRAKDQLHPLLSDLLQSLNKLSLLPPDFEGKSKLVKWLIKLNNMKA 160

                         170       180
                  ....*....|....*....|....*
gi 163776656  195 TDALSPEQIREALMDFDMAYDAYKR 219
Cdd:pfam03997 161 SDELSEEQARQLLFDLESAYNAFYR 185
 
Name Accession Description Interval E-value
VPS28 pfam03997
VPS28 protein;
35-219 9.23e-79

VPS28 protein;


Pssm-ID: 427639  Cd Length: 187  Bit Score: 234.33  E-value: 9.23e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163776656   35 LAAVYEILLTLEHIERAYVHDNIGEAEYTETCKKLLTRFKACRNLLPSDVANDIPAFAATYRLECPAALQRIRVGVPATT 114
Cdd:pfam03997   1 LAELYSIIVTLEHLEKAYIKDSITAKEYTSTCSRLLAQYKTILDELVKDEFPDLEEFMKKYRLDCPAALERLREGVPATV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 163776656  115 EFGSGPSADHVKRSRHVMAATEHFISITDTFSMDIGDVDKLHNEVSGLMDQLNKLDDLSPDHISKRNVLKWLEVLSAMKA 194
Cdd:pfam03997  81 EHSASSSADGGNSAKLVAEATQNFITLMDALKLNYRAKDQLHPLLSDLLQSLNKLSLLPPDFEGKSKLVKWLIKLNNMKA 160

                         170       180
                  ....*....|....*....|....*
gi 163776656  195 TDALSPEQIREALMDFDMAYDAYKR 219
Cdd:pfam03997 161 SDELSEEQARQLLFDLESAYNAFYR 185
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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