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Conserved domains on  [gi|149063417|gb|EDM13740|]
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similar to hypothetical protein FLJ13089, isoform CRA_a [Rattus norvegicus]

Protein Classification

TPR and NatB_MDM20 domain-containing protein( domain architecture ID 11420853)

TPR and NatB_MDM20 domain-containing protein

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
NatB_MDM20 pfam09797
N-acetyltransferase B complex (NatB) non catalytic subunit; This is the non-catalytic subunit ...
 263-658 3.40e-158

N-acetyltransferase B complex (NatB) non catalytic subunit; This is the non-catalytic subunit of the N-terminal acetyltransferase B complex (NatB). The NatB complex catalyzes the acetylation of the amino-terminal methionine residue of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met. In Saccharomyces cerevisiae this subunit is called MDM20 and in Schizosaccharomyces pombe it is called Arm1. NatB acetylates the Tpm1 protein and regulates and tropomyocin-actin interactions. This subunit is required by the NatB complex for the N-terminal acetylation of Tpm1.


:

Pssm-ID: 430834  Cd Length: 368  Bit Score: 469.86  E-value: 3.40e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  263 WQFYLTYFDSVFRLIEEawtppaegehslegevHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIRRLRSQGCNDE 342
Cdd:pfam09797   1 WSVWKLYIDSTFKLIEA----------------KESLEEAQKFIEELIKAEEAKSPKSRNPYLARLELISRLRKRSDDAE 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  343 FRLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLgvvpLSTPTEDKLAlPADIRGLQQHLCVVQLTR 422
Cdd:pfam09797  65 EDLGPLVELILEYFDKFGSKPCCFDDLKPYLELLSDEQRKEFLEKVS----PSKSELDSLV-PGDEKQLRRHINALKLSR 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  423 LLGLYHSMDKNQKLDVVRELMLRYQHGLEFGRSCLKTELQFSDYYCLLAVHVLIDIWREAGEETAVWQALTLLEEGLTHS 502
Cdd:pfam09797 140 CLGLHSKLSEEEKEALVTELLAIYRAGLRLGASLLTTELQPSDDLALLAAHALLDLYRLTGDLTYLIQAILLLEFLLTKS 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  503 PSNAQFKLLLVRIYCVLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYII 582
Cdd:pfam09797 220 PHNFQLKLLLVRLYLLLGAGSLALDLYSKLDIKQIQLDTLGHLLFTRLSTLGPFSLALNLLEQALRFYRNNEKETPEMIS 299

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 149063417  583 QAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTslaesikSMNLRPEEDDVPWEDLRDNRDL 658
Cdd:pfam09797 300 QAYEYGSYSKIEEFIEFRERLKNSLQRAMVRLERRRLDRLLGGDISD-------EMSLYPDEDRIDWSELSDNRDF 368
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 21-146 2.72e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.13  E-value: 2.72e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG4783   14 LLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALA 93

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 149063417 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKN 146
Cdd:COG4783   94 LLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
 
Name Accession Description Interval E-value
NatB_MDM20 pfam09797
N-acetyltransferase B complex (NatB) non catalytic subunit; This is the non-catalytic subunit ...
 263-658 3.40e-158

N-acetyltransferase B complex (NatB) non catalytic subunit; This is the non-catalytic subunit of the N-terminal acetyltransferase B complex (NatB). The NatB complex catalyzes the acetylation of the amino-terminal methionine residue of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met. In Saccharomyces cerevisiae this subunit is called MDM20 and in Schizosaccharomyces pombe it is called Arm1. NatB acetylates the Tpm1 protein and regulates and tropomyocin-actin interactions. This subunit is required by the NatB complex for the N-terminal acetylation of Tpm1.


Pssm-ID: 430834  Cd Length: 368  Bit Score: 469.86  E-value: 3.40e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  263 WQFYLTYFDSVFRLIEEawtppaegehslegevHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIRRLRSQGCNDE 342
Cdd:pfam09797   1 WSVWKLYIDSTFKLIEA----------------KESLEEAQKFIEELIKAEEAKSPKSRNPYLARLELISRLRKRSDDAE 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  343 FRLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLgvvpLSTPTEDKLAlPADIRGLQQHLCVVQLTR 422
Cdd:pfam09797  65 EDLGPLVELILEYFDKFGSKPCCFDDLKPYLELLSDEQRKEFLEKVS----PSKSELDSLV-PGDEKQLRRHINALKLSR 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  423 LLGLYHSMDKNQKLDVVRELMLRYQHGLEFGRSCLKTELQFSDYYCLLAVHVLIDIWREAGEETAVWQALTLLEEGLTHS 502
Cdd:pfam09797 140 CLGLHSKLSEEEKEALVTELLAIYRAGLRLGASLLTTELQPSDDLALLAAHALLDLYRLTGDLTYLIQAILLLEFLLTKS 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  503 PSNAQFKLLLVRIYCVLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYII 582
Cdd:pfam09797 220 PHNFQLKLLLVRLYLLLGAGSLALDLYSKLDIKQIQLDTLGHLLFTRLSTLGPFSLALNLLEQALRFYRNNEKETPEMIS 299

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 149063417  583 QAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTslaesikSMNLRPEEDDVPWEDLRDNRDL 658
Cdd:pfam09797 300 QAYEYGSYSKIEEFIEFRERLKNSLQRAMVRLERRRLDRLLGGDISD-------EMSLYPDEDRIDWSELSDNRDF 368
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 21-146 2.72e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.13  E-value: 2.72e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG4783   14 LLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALA 93

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 149063417 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKN 146
Cdd:COG4783   94 LLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 445-561 2.51e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 2.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417 445 RYQHGLEFGRSCLKTELQFSDYYCLLAvhvliDIWREAGEETavwQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFEP 524
Cdd:COG2956  125 DWEKAIEVLERLLKLGPENAHAYCELA-----ELYLEQGDYD---EAIEALEKALKLDPDCARALLLLAELYLEQGDYEE 196

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 149063417 525 VVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQ 561
Cdd:COG2956  197 AIAALERALEQDPDYLPALPRLAELYEKLGDPEEALE 233
 
Name Accession Description Interval E-value
NatB_MDM20 pfam09797
N-acetyltransferase B complex (NatB) non catalytic subunit; This is the non-catalytic subunit ...
 263-658 3.40e-158

N-acetyltransferase B complex (NatB) non catalytic subunit; This is the non-catalytic subunit of the N-terminal acetyltransferase B complex (NatB). The NatB complex catalyzes the acetylation of the amino-terminal methionine residue of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met. In Saccharomyces cerevisiae this subunit is called MDM20 and in Schizosaccharomyces pombe it is called Arm1. NatB acetylates the Tpm1 protein and regulates and tropomyocin-actin interactions. This subunit is required by the NatB complex for the N-terminal acetylation of Tpm1.


Pssm-ID: 430834  Cd Length: 368  Bit Score: 469.86  E-value: 3.40e-158
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  263 WQFYLTYFDSVFRLIEEawtppaegehslegevHCSAEDAVKFIEDRITEASQSSRHVRGPHLAKLELIRRLRSQGCNDE 342
Cdd:pfam09797   1 WSVWKLYIDSTFKLIEA----------------KESLEEAQKFIEELIKAEEAKSPKSRNPYLARLELISRLRKRSDDAE 64

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  343 FRLGDPEELMFQYFKKFGDKPCCFTDLKVFVDLLPAAQCTQFINQLLgvvpLSTPTEDKLAlPADIRGLQQHLCVVQLTR 422
Cdd:pfam09797  65 EDLGPLVELILEYFDKFGSKPCCFDDLKPYLELLSDEQRKEFLEKVS----PSKSELDSLV-PGDEKQLRRHINALKLSR 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  423 LLGLYHSMDKNQKLDVVRELMLRYQHGLEFGRSCLKTELQFSDYYCLLAVHVLIDIWREAGEETAVWQALTLLEEGLTHS 502
Cdd:pfam09797 140 CLGLHSKLSEEEKEALVTELLAIYRAGLRLGASLLTTELQPSDDLALLAAHALLDLYRLTGDLTYLIQAILLLEFLLTKS 219

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  503 PSNAQFKLLLVRIYCVLGAFEPVVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALRFFHSNQKDTSEYII 582
Cdd:pfam09797 220 PHNFQLKLLLVRLYLLLGAGSLALDLYSKLDIKQIQLDTLGHLLFTRLSTLGPFSLALNLLEQALRFYRNNEKETPEMIS 299

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 149063417  583 QAYKYGAFEKIPEFIAFRNRLNNSLHFAQVRTERMLLDLLLEANISTslaesikSMNLRPEEDDVPWEDLRDNRDL 658
Cdd:pfam09797 300 QAYEYGSYSKIEEFIEFRERLKNSLQRAMVRLERRRLDRLLGGDISD-------EMSLYPDEDRIDWSELSDNRDF 368
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 21-146 2.72e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.13  E-value: 2.72e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG4783   14 LLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALA 93

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 149063417 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKN 146
Cdd:COG4783   94 LLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 13-160 7.08e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.09  E-value: 7.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  13 RRLRPIYDYLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREM 92
Cdd:COG3914   80 LLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL 159

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 149063417  93 HRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYFWSVMSLIMQS 160
Cdd:COG3914  160 GRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQA 227
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 21-142 2.35e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.16  E-value: 2.35e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG3914  122 LLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIA 201

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 149063417 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKI 142
Cdd:COG3914  202 AYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAAL 243
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 21-220 5.11e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.59  E-value: 5.11e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG2956   52 YRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIE 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYfwsvmSLIMQSISARDENLSKtmflplAERM 180
Cdd:COG2956  132 VLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARA-----LLLLAELYLEQGDYEE------AIAA 200

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 149063417 181 VEKMVKEDKIEAEAEVELYYmILERLGKYQEALDVIRGKL 220
Cdd:COG2956  201 LERALEQDPDYLPALPRLAE-LYEKLGDPEEALELLRKAL 239
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
21-156 3.46e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.40  E-value: 3.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG0457   18 YRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALE 97

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 149063417 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYkkmQQAGMALYKIVPKNPYYFWSVMSL 156
Cdd:COG0457   98 DYDKALELDPDDAEALYNLGLALLELGRY---DEAIEAYERALELDPDDADALYNL 150
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 20-220 6.93e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.12  E-value: 6.93e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  20 DYLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVT 99
Cdd:COG2956   85 DYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAI 164

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417 100 KLYEAAVKKVPNSEEYHSHLFMAYARVGEYkkmQQAGMALYKIVPKNPYYFwSVMSLIMQSISARDEnlsktmfLPLAER 179
Cdd:COG2956  165 EALEKALKLDPDCARALLLLAELYLEQGDY---EEAIAALERALEQDPDYL-PALPRLAELYEKLGD-------PEEALE 233

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 149063417 180 MVEKMVKEDkiEAEAEVELYYMILERLGKYQEALDVIRGKL 220
Cdd:COG2956  234 LLRKALELD--PSDDLLLALADLLERKEGLEAALALLERQL 272
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 30-147 1.70e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 1.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  30 AIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKV 109
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 149063417 110 PNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNP 147
Cdd:COG4235   82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
21-131 5.12e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.93  E-value: 5.12e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG0457   52 YLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIE 131

                         90       100       110
                 ....*....|....*....|....*....|.
gi 149063417 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKK 131
Cdd:COG0457  132 AYERALELDPDDADALYNLGIALEKLGRYEE 162
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
51-217 1.78e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.39  E-value: 1.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  51 KAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYk 130
Cdd:COG0457   14 LGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRY- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417 131 kmQQAGMALYKIVPKNPYYF--WSVMSLIMQSISARDEnlsktmflplAERMVEKMVKEDKIEAEAEVELyYMILERLGK 208
Cdd:COG0457   93 --EEALEDYDKALELDPDDAeaLYNLGLALLELGRYDE----------AIEAYERALELDPDDADALYNL-GIALEKLGR 159


                 ....*....
gi 149063417 209 YQEALDVIR 217
Cdd:COG0457  160 YEEALELLE 168
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 47-151 1.76e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.57  E-value: 1.76e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  47 AKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARV 126
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                         90       100
                 ....*....|....*....|....*....
gi 149063417 127 GEYKKmqqaGMALYKIV----PKNPYYFW 151
Cdd:COG4783   86 GDYDE----ALALLEKAlkldPEHPEAYL 110
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 50-217 2.10e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.42  E-value: 2.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  50 LKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEY 129
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417 130 KKMQQAGMALYKIVPKNPYYFWSVMslimqSISARDENLSKtmflplAERMVEKMVKEDKIEAEAEVELyYMILERLGKY 209
Cdd:COG2956   93 DRAEELLEKLLELDPDDAEALRLLA-----EIYEQEGDWEK------AIEVLERLLKLGPENAHAYCEL-AELYLEQGDY 160


                 ....*...
gi 149063417 210 QEALDVIR 217
Cdd:COG2956  161 DEAIEALE 168
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 55-135 3.25e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.34  E-value: 3.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  55 LQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQ 134
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143


                 .
gi 149063417 135 A 135
Cdd:COG5010  144 A 144
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 8-115 5.74e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.84  E-value: 5.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417   8 QDPND----RRLRPIYdyLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQ 83
Cdd:COG4235   12 ANPNDaegwLLLGRAY--LRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALY 89

                         90       100       110
                 ....*....|....*....|....*....|..
gi 149063417  84 ALTILYREMHRPELVTKLYEAAVKKVPNSEEY 115
Cdd:COG4235   90 LLGLAAFQQGDYAEAIAAWQKLLALLPADAPA 121
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 63-151 3.57e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 41.53  E-value: 3.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  63 EAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKI 142
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                 ....*....
gi 149063417 143 VPKNPYYFW 151
Cdd:COG4235   81 DPDNPEALY 89
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
55-145 6.49e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.77  E-value: 6.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  55 LQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKlYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQ 134
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                         90
                 ....*....|.
gi 149063417 135 AGMALYKIVPK 145
Cdd:COG3063   81 YLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 21-110 7.44e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.10  E-value: 7.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143

                         90
                 ....*....|
gi 149063417 101 LYEAAVKKVP 110
Cdd:COG5010  144 ALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
21-111 9.49e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.38  E-value: 9.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  21 YLDNGNNKMAIQQADKLLKKHRDLhcAKVLKAIG--LQRTGRQEEAFTLaQEVAALEPTDDNSLQALTILYREMHRPELV 98
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDN--ADALNNLGllLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEA 78

                         90
                 ....*....|...
gi 149063417  99 TKLYEAAVKKVPN 111
Cdd:COG3063   79 LAYLERALELDPS 91
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
21-140 1.51e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.53  E-value: 1.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  21 YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTK 100
Cdd:COG0457   86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALE 165

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 149063417 101 LYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALY 140
Cdd:COG0457  166 LLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQ 205
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
73-217 1.96e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.15  E-value: 1.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  73 ALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARVGEYKKMQQAGMALYKIVPKNPYYfWS 152
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEA-LN 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 149063417 153 VMSLIMQSISARDEnlsktmflplAERMVEKMVKEDKIEAEAeveLYY--MILERLGKYQEALDVIR 217
Cdd:COG0457   81 NLGLALQALGRYEE----------ALEDYDKALELDPDDAEA---LYNlgLALLELGRYDEAIEAYE 134
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 445-561 2.51e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.87  E-value: 2.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417 445 RYQHGLEFGRSCLKTELQFSDYYCLLAvhvliDIWREAGEETavwQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFEP 524
Cdd:COG2956  125 DWEKAIEVLERLLKLGPENAHAYCELA-----ELYLEQGDYD---EAIEALEKALKLDPDCARALLLLAELYLEQGDYEE 196

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 149063417 525 VVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQ 561
Cdd:COG2956  197 AIAALERALEQDPDYLPALPRLAELYEKLGDPEEALE 233
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 47-147 2.72e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.56  E-value: 2.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417  47 AKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLQALTILYREMHRPELVTKLYEAAVKKVPNSEEYHSHLFMAYARV 126
Cdd:COG5010   22 TLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRS 101

                         90       100
                 ....*....|....*....|.
gi 149063417 127 GEYKKMQQAGMALYKIVPKNP 147
Cdd:COG5010  102 GDKDEAKEYYEKALALSPDNP 122
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 445-568 3.84e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.63  E-value: 3.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417 445 RYQHGLEFGRSCLKTELQFSDYYCLLAvhvliDIWREAGEETavwQALTLLEEGLTHSPSNAQFKLLLVRIYCVLGAFEP 524
Cdd:COG4783   19 DYDEAEALLEKALELDPDNPEAFALLG-----EILLQLGDLD---EAIVLLHEALELDPDEPEARLNLGLALLKAGDYDE 90

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 149063417 525 VVDLYSSLDAKHIQHDTIGYLLTRYAASLGQYAAASQSCNFALR 568
Cdd:COG4783   91 ALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 9-108 4.62e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.10  E-value: 4.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149063417   9 DPNDRRLRPIYD--YLDNGNNKMAIQQADKLLKKHRDLHCAKVLKAIGLQRTGRQEEAFTLAQEVAALEPTDDNSLqALT 86
Cdd:COG2956  174 DPDCARALLLLAelYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLL-ALA 252

                         90       100
                 ....*....|....*....|..
gi 149063417  87 ILYREMHRPELVTKLYEAAVKK 108
Cdd:COG2956  253 DLLERKEGLEAALALLERQLRR 274
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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