NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|149041493|gb|EDL95334|]
View 

similar to hypothetical protein FLJ21827, isoform CRA_b [Rattus norvegicus]

Protein Classification

intraflagellar transport 46 family protein( domain architecture ID 37868)

intraflagellar transport protein 46 (IFT46) family protein such as IFT46 that forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia

Gene Ontology:  GO:0005929|GO:0060271
PubMed:  25722189|17312020

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
IFT46_B_C super family cl13716
Intraflagellar transport complex B protein 46 C terminal; This family of proteins is found in ...
 1-64 8.37e-40

Intraflagellar transport complex B protein 46 C terminal; This family of proteins is found in eukaryotes. Proteins in this family are typically between 298 and 416 amino acids in length. IFT46 is a flagellar protein of complex B. Like all IFT proteins, it is required for transport of IFT particles into the flagella.


The actual alignment was detected with superfamily member pfam12317:

Pssm-ID: 463532  Cd Length: 203  Bit Score: 130.77  E-value: 8.37e-40
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 149041493    1 MPDIDTLMQEWSPEFEELLGKVSLPTVEIDCSLAEYIDMICAILDIPFYKSRIQSLHLLFSLYS 64
Cdd:pfam12317 140 MPDIETLMQEWPPEFEEALNKVGLPSAELDCDLAEYVDIICAILDIPVYGSRIESLHLLFTLYL 203
 
Name Accession Description Interval E-value
IFT46_B_C pfam12317
Intraflagellar transport complex B protein 46 C terminal; This family of proteins is found in ...
 1-64 8.37e-40

Intraflagellar transport complex B protein 46 C terminal; This family of proteins is found in eukaryotes. Proteins in this family are typically between 298 and 416 amino acids in length. IFT46 is a flagellar protein of complex B. Like all IFT proteins, it is required for transport of IFT particles into the flagella.


Pssm-ID: 463532  Cd Length: 203  Bit Score: 130.77  E-value: 8.37e-40
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 149041493    1 MPDIDTLMQEWSPEFEELLGKVSLPTVEIDCSLAEYIDMICAILDIPFYKSRIQSLHLLFSLYS 64
Cdd:pfam12317 140 MPDIETLMQEWPPEFEEALNKVGLPSAELDCDLAEYVDIICAILDIPVYGSRIESLHLLFTLYL 203
 
Name Accession Description Interval E-value
IFT46_B_C pfam12317
Intraflagellar transport complex B protein 46 C terminal; This family of proteins is found in ...
 1-64 8.37e-40

Intraflagellar transport complex B protein 46 C terminal; This family of proteins is found in eukaryotes. Proteins in this family are typically between 298 and 416 amino acids in length. IFT46 is a flagellar protein of complex B. Like all IFT proteins, it is required for transport of IFT particles into the flagella.


Pssm-ID: 463532  Cd Length: 203  Bit Score: 130.77  E-value: 8.37e-40
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 149041493    1 MPDIDTLMQEWSPEFEELLGKVSLPTVEIDCSLAEYIDMICAILDIPFYKSRIQSLHLLFSLYS 64
Cdd:pfam12317 140 MPDIETLMQEWPPEFEEALNKVGLPSAELDCDLAEYVDIICAILDIPVYGSRIESLHLLFTLYL 203
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH