|
Name |
Accession |
Description |
Interval |
E-value |
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
109-466 |
4.20e-20 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 96.55 E-value: 4.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 109 PSPPERQNPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAGPLISPEPQAPCLPAEASKAAPvpcPERVD 188
Cdd:PHA03247 2592 PPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR---PRRAR 2668
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 189 PPCELPELEKPERGPSPESVKSALVSSkppkhSSFADTGAAPSalSPESPVLATSPEPWGPSLSASPESRKPARTASPEP 268
Cdd:PHA03247 2669 RLGRAAQASSPPQRPRRRAARPTVGSL-----TSLADPPPPPP--TPEPAPHALVSATPLPPGPAAARQASPALPAAPAP 2741
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 269 rkPSPAESP-----ELWKPFPAIASEPRRPTPAVSPGSwkPGPPGSPRPWKSSPSATS----GPWKSSKPVQPMSPGPWK 339
Cdd:PHA03247 2742 --PAVPAGPatpggPARPARPPTTAGPPAPAPPAAPAA--GPPRRLTRPAVASLSESReslpSPWDPADPPAAVLAPAAA 2817
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 340 PIPSVSPGPWKPAPsmSTASWKSSVSSGSWKTPPTSPESWKSGPPELRKTALPLSPEHWKAVPPVSPELRRPGPPLSPEI 419
Cdd:PHA03247 2818 LPPAASPAGPLPPP--TSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRST 2895
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 148690223 420 RSPAGSPELKKPSSSPDLWKVSPDQRKTSPASLDFPEPQKSSCGSPP 466
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP 2942
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
88-560 |
6.44e-18 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 89.23 E-value: 6.44e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 88 SDKWSEQPKEQPSKDTESGKSPSPPERQNPAFDPAEARPTPALPMEAQKTSPSlcpESQASGPPVLEPQGAGPLISPEPQ 167
Cdd:PHA03247 2605 RGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPA---PGRVSRPRRARRLGRAAQASSPPQ 2681
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 168 APCLPAEASKAAPVPCPERVDPPcelpelekperGPSPESVKSALVSSKPPKHSSFADTGAAPSAL-------SPESPVL 240
Cdd:PHA03247 2682 RPRRRAARPTVGSLTSLADPPPP-----------PPTPEPAPHALVSATPLPPGPAAARQASPALPaapappaVPAGPAT 2750
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 241 ATSPEPWG-PSLSASPESRKPAR--TASPEPRKPSPAESPELwkpfPAIASEPRRPTPAVSPGSwkPGPPGSPRPWKSSP 317
Cdd:PHA03247 2751 PGGPARPArPPTTAGPPAPAPPAapAAGPPRRLTRPAVASLS----ESRESLPSPWDPADPPAA--VLAPAAALPPAASP 2824
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 318 SATSGPWKSSKPVQPMSPGPWKPIP-----SVSPG------------PWKPA-----PSMSTASWKSSVSSGSWKTPPTS 375
Cdd:PHA03247 2825 AGPLPPPTSAQPTAPPPPPGPPPPSlplggSVAPGgdvrrrppsrspAAKPAaparpPVRRLARPAVSRSTESFALPPDQ 2904
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 376 PESWKSGPPELRKTALPLSPEHWKAVPPVSPElRRPGPPLSPEiRSPAGSPELKKPSSSPDLWKVSPDQ----RKTSPAS 451
Cdd:PHA03247 2905 PERPPQPQAPPPPQPQPQPPPPPQPQPPPPPP-PRPQPPLAPT-TDPAGAGEPSGAVPQPWLGALVPGRvavpRFRVPQP 2982
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 452 LDFPEPQKSSCGSPPDL-------WKSSFIM--ESQKPNVfseTRKHTASGSSESPKvaSDIWKPVLSIDAEPRKSTLFP 522
Cdd:PHA03247 2983 APSREAPASSTPPLTGHslsrvssWASSLALheETDPPPV---SLKQTLWPPDDTED--SDADSLFDSDSERSDLEALDP 3057
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 148690223 523 EPTKAVLPASPEPRKRALFPESRK----HVFLPELPKSAVFS 560
Cdd:PHA03247 3058 LPPEPHDPFAHEPDPATPEAGAREspssQFGPPPLSANAALS 3099
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
88-443 |
6.02e-16 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 82.53 E-value: 6.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 88 SDKWSEQPKEQPSKDTESGKSPSPPErqnPAFDPAEARPTPALPM-EAQKTSPSLCPESQASGPPVLEPQGAGPLISPEP 166
Cdd:PHA03307 93 STLAPASPAREGSPTPPGPSSPDPPP---PTPPPASPPPSPAPDLsEMLRPVGSPGPPPAASPPAAGASPAAVASDAASS 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 167 QAPCLPA---EASKAAPVPCPERVDPPCELPELEKPERGP-SPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLAT 242
Cdd:PHA03307 170 RQAALPLsspEETARAPSSPPAEPPPSTPPAAASPRPPRRsSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGW 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 243 SPEPWGPSLSASPESRKPARTASPEPRKPSPAESPElwKPFPAIASEPRRPTPAVSPGSWKPGPPGSPRPWKSSPSA-TS 321
Cdd:PHA03307 250 GPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPA--SSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESsSS 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 322 GPWKSSKPVQPMSPGPWKPiPSVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTSPeswkSGPPELRKT-ALPLSPEHWKA 400
Cdd:PHA03307 328 STSSSSESSRGAAVSPGPS-PSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAAS----AGRPTRRRArAAVAGRARRRD 402
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 148690223 401 VPPVSPELRRPGPPLSPEIRSPAGSPELKKPSSSPDLWKVSPD 443
Cdd:PHA03307 403 ATGRFPAGRPRPSPLDAGAASGAFYARYPLLTPSGEPWPGSPP 445
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
234-468 |
1.14e-14 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 77.89 E-value: 1.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 234 SPESPVLATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPELWKPFPAIASEPRRPTPAVSPGSWKPGPPGSPRPW 313
Cdd:NF033839 302 SPQPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPE 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 314 KSSPSATSGPwksSKPVQPMSPGPWKPIPSVSPGPWKPAPSMSTASWKSSVSSGSWktpPTSPESWKSGPPELRKTALPL 393
Cdd:NF033839 382 TPKPEVKPQP---EKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQ---PEKPKPEVKPQPEKPKPEVKP 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 394 SPEhwKAVPPVSPELRRPGPPLSPEIRSPAGS-----PELKKPSSSPDLW--KVSPDQRKTSPASLDFPEPQKSSCGSPP 466
Cdd:NF033839 456 QPE--TPKPEVKPQPEKPKPEVKPQPEKPKPDnskpqADDKKPSTPNNLSkdKQPSNQASTNEKATNKPKKSLPSTGSIS 533
|
..
gi 148690223 467 DL 468
Cdd:NF033839 534 NL 535
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
80-480 |
9.85e-14 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 75.59 E-value: 9.85e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 80 HITARHAASDKWSEQPKEQPSKDTESGKSPSPPERQNPAFDPAEARPTPALPMEAQKTSPslcPESQASGPPVLEPQGAG 159
Cdd:PHA03307 49 ELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTP---PGPSSPDPPPPTPPPAS 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 160 PLISPEPQAPCLPAEASKAAPVPCPERVDPPCELPELEKPERGPSPesvkSALVSSKPPKHSSFADTGAAPSALSPESPV 239
Cdd:PHA03307 126 PPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQ----AALPLSSPEETARAPSSPPAEPPPSTPPAA 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 240 LATSPEPWGPSLSASPESRKPARTASPEpRKPSPAESPELWKPFPAIASEPRRPTPAVSPGSWK-PGPPGSPRPWKSsPS 318
Cdd:PHA03307 202 ASPRPPRRSSPISASASSPAPAPGRSAA-DDAGASSSDSSSSESSGCGWGPENECPLPRPAPITlPTRIWEASGWNG-PS 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 319 ATSGPWKSSKPVQPMSPgpwKPIPSVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTSPESWKSGPPELRKTALPLSPEHW 398
Cdd:PHA03307 280 SRPGPASSSSSPRERSP---SPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRP 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 399 KAVPPVSPELRRPGPPLSPEIRS-PAGSPELKKPSSSPDLWKVSPDQRKTSPASLDFPEPQKSSCGSPPDLWKSSFIMES 477
Cdd:PHA03307 357 PPPADPSSPRKRPRPSRAPSSPAaSAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYPLLTPS 436
|
...
gi 148690223 478 QKP 480
Cdd:PHA03307 437 GEP 439
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
118-461 |
3.77e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 73.82 E-value: 3.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 118 AFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVlEPQGAGPLISPEPQAPCLPAEASKAAPVPCPervdpPCELPELE 197
Cdd:PHA03247 2548 AGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAV-TSRARRPDAPPQSARPRAPVDDRGDPRGPAP-----PSPLPPDT 2621
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 198 KPERGPSPesvksalvsskppkhssfadtGAAPSALSPESPVLATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESP 277
Cdd:PHA03247 2622 HAPDPPPP---------------------SPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPP 2680
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 278 ELWKPFPA------IASEPRRP----TPAVSPGSWKPG---PPGSPRPWKSSPSATSGPWKSSKPVQPMSPGPWKPI--P 342
Cdd:PHA03247 2681 QRPRRRAArptvgsLTSLADPPppppTPEPAPHALVSAtplPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARParP 2760
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 343 SVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTSPESWKSGPPELRKTALPLSPEHWKAVPPVSPELRRPgPPLSPEIRSP 422
Cdd:PHA03247 2761 PTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLP-PPTSAQPTAP 2839
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 148690223 423 AGSPELKKPSSSPDLWkVSP--DQRKTSPASLDFPEPQKSS 461
Cdd:PHA03247 2840 PPPPGPPPPSLPLGGS-VAPggDVRRRPPSRSPAAKPAAPA 2879
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
95-427 |
2.59e-11 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 67.32 E-value: 2.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 95 PKEQPSKDTESGKSP-SPPERQNPAFDPAEARPTPALPMEAQ--KTSPSLCPESQASGPPVLEPQGAGPLISPEP--QAP 169
Cdd:PRK07764 394 PAAAAPSAAAAAPAAaPAPAAAAPAAAAAPAPAAAPQPAPAPapAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPapAAA 473
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 170 CLPAEASKAAPVPCPERVDPPcELPELEKPERGPSP------------ESVK-------SALVS---------------- 214
Cdd:PRK07764 474 PEPTAAPAPAPPAAPAPAAAP-AAPAAPAAPAGADDaatlrerwpeilAAVPkrsrktwAILLPeatvlgvrgdtlvlgf 552
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 215 SKPPKHSSFADT------------------------GAAPSALSPESPVLATSPePWGPSLSASPESRKPARTASPEPRK 270
Cdd:PRK07764 553 STGGLARRFASPgnaevlvtalaeelggdwqveavvGPAPGAAGGEGPPAPASS-GPPEEAARPAAPAAPAAPAAPAPAG 631
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 271 PSPAESPELWKPFPAIASEPRRPTPAVSP-----GSWKPGPPGSPRPWKSSPSATSGPWKSSKPV---QPMSPGPWKPIP 342
Cdd:PRK07764 632 AAAAPAEASAAPAPGVAAPEHHPKHVAVPdasdgGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAapaQPAPAPAATPPA 711
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 343 SVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTSPESWKSGPPELRKTALPLSPEHWKAVPPVSPELRRPGPPLSPEIRSP 422
Cdd:PRK07764 712 GQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAP 791
|
....*
gi 148690223 423 AGSPE 427
Cdd:PRK07764 792 SMDDE 796
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
146-418 |
2.82e-11 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 67.21 E-value: 2.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 146 QASGPPVLEPQGAGPLISPEPQAPCLPAEASKAAPVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKHSSFAD 225
Cdd:PRK12323 371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAP 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 226 TGAAPSALSPESPVLATSPEPWGPSLSASPESRKPARTASPEPRKPSPAEspELWKPFPAIASEPRRPTPAVSPGSwkpg 305
Cdd:PRK12323 451 APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWE--ELPPEFASPAPAQPDAAPAGWVAE---- 524
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 306 ppGSPRPWKSSPSATSGPWKSSKPVQPMSPGPWKPIPSVSPGPwkPAPSMStaswkssvssgswKTPPTSPESWKSGPPE 385
Cdd:PRK12323 525 --SIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRP--PRASAS-------------GLPDMFDGDWPALAAR 587
|
250 260 270
....*....|....*....|....*....|....*.
gi 148690223 386 LRKTALPLSPEH---WKAVPPVSPELRRPGPPLSPE 418
Cdd:PRK12323 588 LPVRGLAQQLARqseLAGVEGDTVRLRVPVPALAEA 623
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
144-539 |
9.26e-11 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 65.96 E-value: 9.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 144 ESQASGPPVLEPQGAGPLISPEPQAPCLPAEASKAAPVPCPERVDPPCELpelEKPERGPSPESVKSAlVSSKPPKHSSF 223
Cdd:PHA03307 19 EFFPRPPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPP---TGPPPGPGTEAPANE-SRSTPTWSLST 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 224 ADTGAAPSALSPESPVLATSPEPWGPSLSASPESRKParTASPEPRKPSPAESPElWKPFPAIASEPRRPTPAVSPGSWK 303
Cdd:PHA03307 95 LAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPA--PDLSEMLRPVGSPGPP-PAASPPAAGASPAAVASDAASSRQ 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 304 PGPP----GSPRPWKSSPSATSGPWKSSKPVQPMSPGPWKPIPSVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTSPESW 379
Cdd:PHA03307 172 AALPlsspEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGP 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 380 KSGPPELRKTALPLSPEHWKAVPPVSPELRRPGPPLSPEIRSPAGSPELKKPSSSPdlwkvspdqRKTSPASLDFPEPQK 459
Cdd:PHA03307 252 ENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGP---------APSSPRASSSSSSSR 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 460 SScgsppDLWKSSFIMESQKPNVFSETRKHTASGSSESPkvasdiwKPVLSIDAEPRKSTLFPEP-TKAVLPASPEPRKR 538
Cdd:PHA03307 323 ES-----SSSSTSSSSESSRGAAVSPGPSPSRSPSPSRP-------PPPADPSSPRKRPRPSRAPsSPAASAGRPTRRRA 390
|
.
gi 148690223 539 A 539
Cdd:PHA03307 391 R 391
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
202-426 |
7.61e-10 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 62.59 E-value: 7.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 202 GPSPESVKSALVSSKPPKHSSFADTGAAPSAlSPESPVLATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPELWK 281
Cdd:PRK12323 371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAA-PPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPA 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 282 PFPAIASEPRRPTPAVSPGSWKPGPPGSPRPWKSSPSATSGPwksskpvQPMSPGPWKPIPS--VSPGPWKPAPSMSTAS 359
Cdd:PRK12323 450 PAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP-------ADDDPPPWEELPPefASPAPAQPDAAPAGWV 522
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 148690223 360 WKSSVSSGSWKTPPTSPESWKSGPPelrktalPLSPEHWKAVPPVSPelrrPGPPLSPEIRSPAGSP 426
Cdd:PRK12323 523 AESIPDPATADPDDAFETLAPAPAA-------APAPRAAAATEPVVA----PRPPRASASGLPDMFD 578
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
83-302 |
1.08e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 61.82 E-value: 1.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 83 ARHAASDKWSEQPKEQPSKDTESGKSPSPPErqnPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAGPLI 162
Cdd:PRK12323 375 ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAA---PAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 163 SPEPQAPClPAEASKAAPVPCPERVDPPCELPELEKPERGPSPESVksalvsskPPKHS---SFADTGAAPSALSPESPV 239
Cdd:PRK12323 452 PAPAAAPA-AAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDP--------PPWEElppEFASPAPAQPDAAPAGWV 522
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 148690223 240 LATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPElwKPFPAIASEPRrpTPAVSPGSW 302
Cdd:PRK12323 523 AESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVV--APRPPRASASG--LPDMFDGDW 581
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
230-455 |
7.21e-09 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 59.69 E-value: 7.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 230 PSALSPESPVlaTSPEPWGPSLSASPESRKPARTASPEP---RKPSPAESPELWKPFPaIASEPRRPTPAVSPGSWKPGP 306
Cdd:PHA03379 411 PTYGTPRPPV--EKPRPEVPQSLETATSHGSAQVPEPPPvhdLEPGPLHDQHSMAPCP-VAQLPPGPLQDLEPGDQLPGV 487
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 307 PGSPRPWKSSPSATSGPWksskpVQPMSPGPWKpIPSVSPGPWKPAPsMSTASWKSSVSSGSWKTPPTSPESWKSGPPE- 385
Cdd:PHA03379 488 VQDGRPACAPVPAPAGPI-----VRPWEASLSQ-VPGVAFAPVMPQP-MPVEPVPVPTVALERPVCPAPPLIAMQGPGEt 560
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 148690223 386 --LRKTALPLSPEHWKAVPP--VSPELRRPGPPLSPEIRSPAGSPELKKPSSSPDLWKVSPDQRKTSPASLDFP 455
Cdd:PHA03379 561 sgIVRVRERWRPAPWTPNPPrsPSQMSVRDRLARLRAEAQPYQASVEVQPPQLTQVSPQQPMEYPLEPEQQMFP 634
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
106-353 |
9.71e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 59.09 E-value: 9.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 106 GKSPSPPERQNPAfdPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAGPLISPEPQAPCLPAE------ASKAA 179
Cdd:PRK07003 370 GGVPARVAGAVPA--PGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATAdrgddaADGDA 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 180 PVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKhssfADTGAAPSALSPESPVLATSPEPWGPSlsASPESRK 259
Cdd:PRK07003 448 PVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPD----AAFEPAPRAAAPSAATPAAVPDARAPA--AASREDA 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 260 PARTASPEPRKPSPAespelwkpfPAIASEPRRPTPA-------------VSPGSWKpGPPGSPRPwKSSPSATSGPWKS 326
Cdd:PRK07003 522 PAAAAPPAPEARPPT---------PAAAAPAARAGGAaaaldvlrnagmrVSSDRGA-RAAAAAKP-AAAPAAAPKPAAP 590
|
250 260
....*....|....*....|....*..
gi 148690223 327 SKPVQPMSPGPWKPIPSVSPGPWKPAP 353
Cdd:PRK07003 591 RVAVQVPTPRARAATGDAPPNGAARAE 617
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
95-347 |
3.53e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 54.02 E-value: 3.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 95 PKEQPSKDTESGKSPSPPERQNPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVLE--PQGAGPLISPEPQA-PCL 171
Cdd:PHA03307 189 PPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGwgPENECPLPRPAPITlPTR 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 172 PAEASkaapVPCPERVDPPCELPELEKPERGPSPESVKS---ALVSSKPPKHSSFADTGAAPSALSPESPVLATSPEPWG 248
Cdd:PHA03307 269 IWEAS----GWNGPSSRPGPASSSSSPRERSPSPSPSSPgsgPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPG 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 249 PSL--SASPESRKPARTASPEPRKPSPAESPelwkPFPAIAS-EPRRPTPAVSPGSW-----KPGPPGSPRPWKSSPSAT 320
Cdd:PHA03307 345 PSPsrSPSPSRPPPPADPSSPRKRPRPSRAP----SSPAASAgRPTRRRARAAVAGRarrrdATGRFPAGRPRPSPLDAG 420
|
250 260
....*....|....*....|....*....
gi 148690223 321 SGPWKSSKPVQPMSPG--PWKPIPSVSPG 347
Cdd:PHA03307 421 AASGAFYARYPLLTPSgePWPGSPPPPPG 449
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
222-444 |
2.00e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 51.42 E-value: 2.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 222 SFADTGAAPSALSPES---------PVLATSPEPWG-----PSLSASPESRKPARTASPEPRKPSPAESPElwKPFPAIA 287
Cdd:PRK12323 334 QIANLGRSELALAPDEyagftmtllRMLAFRPGQSGggagpATAAAAPVAQPAPAAAAPAAAAPAPAAPPA--APAAAPA 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 288 SEPRRPTPAVSPGSWKPGPPGSPRPWKSSPSatsGPWKSSKPVQPMSPGPWKPIPSVSPGPwKPAPSMSTASWKSSVSSG 367
Cdd:PRK12323 412 AAAAARAVAAAPARRSPAPEALAAARQASAR---GPGGAPAPAPAPAAAPAAAARPAAAGP-RPVAAAAAAAPARAAPAA 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 368 SWKTPPTSPESWKSGPPELRKTALPLS---PEHWKAVPPVSPELRRPGPPLSPEIRSPAGSP-ELKKPSSSPDLWKVSPD 443
Cdd:PRK12323 488 APAPADDDPPPWEELPPEFASPAPAQPdaaPAGWVAESIPDPATADPDDAFETLAPAPAAAPaPRAAAATEPVVAPRPPR 567
|
.
gi 148690223 444 Q 444
Cdd:PRK12323 568 A 568
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
95-480 |
2.26e-06 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 51.31 E-value: 2.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 95 PKEQPSKDTESGKSPSPPerqnPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAgplisPEPQAPCLPae 174
Cdd:pfam03154 183 PPSPPPPGTTQAATAGPT----PSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRL-----PSPHPPLQP-- 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 175 askaAPVPCPERVDPPCELPELEKPERG-PSPESVKSALVSSKPPkhssfadtgaAPSALSPESPVLATSPEPWGPSLSA 253
Cdd:pfam03154 252 ----MTQPPPPSQVSPQPLPQPSLHGQMpPMPHSLQTGPSHMQHP----------VPPQPFPLTPQSSQSQVPPGPSPAA 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 254 SPESRKPARTASPEPRKPSPAESPELWKPfPAIASEPRRPTPAVSPGSWKPGPPGsprpwKSSPSATSGPWKSSKPVQPM 333
Cdd:pfam03154 318 PGQSQQRIHTPPSQSQLQSQQPPREQPLP-PAPLSMPHIKPPPTTPIPQLPNPQS-----HKHPPHLSGPSPFQMNSNLP 391
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 334 SPGPWKPIPSVSPgpwKPAPSMSTASWKSSVSSGSWKTPPTSPESWKSGPPELRKTALPLSPEHWKAVPPVSPELRRPGP 413
Cdd:pfam03154 392 PPPALKPLSSLST---HHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFV 468
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 148690223 414 PLSPEIRSPAGSPELKKPSSSPDLwkvspDQRKTSPASLDFPEPQKSSCGSPPDLWKSSFIMESQKP 480
Cdd:pfam03154 469 PGGPPPITPPSGPPTSTSSAMPGI-----QPPSSASVSSSGPVPAAVSCPLPPVQIKEEALDEAEEP 530
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
155-295 |
3.03e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 50.87 E-value: 3.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 155 PQGAGPLISPEPQAPCLPAEASKAAPVPCPERVDPPCelpelekpeRGPSPESVKSALVSSKPPKHSSFAdtgAAPSALS 234
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPA---------PAAAPAAAASAPAAPPAAAPPAPV---AAPAAAA 433
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 148690223 235 PES---PVLATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPElwkpfPAIASEPRRPTP 295
Cdd:PRK14951 434 PAAapaAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPA-----AAPAAARLTPTE 492
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
130-466 |
3.42e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 50.75 E-value: 3.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 130 LPMEAQKTSPSLCPESQASGPPVLEPQGAGPlispEPQAPCLPAEASKAAPVPCPERVDPPCELPELEKPERGPSPESVK 209
Cdd:PRK07764 385 LGVAGGAGAPAAAAPSAAAAAPAAAPAPAAA----APAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAA 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 210 SALVSSKPPKHSSFADTGAAPSALSPESPVLATSPEPWGPSLSASP-------------------ESRKPARTASPEPRk 270
Cdd:PRK07764 461 APSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGAddaatlrerwpeilaavpkRSRKTWAILLPEAT- 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 271 PSPAESPELWKPFPAIASEPR----------------------RPTPAVSPGSWKPGPPGSPRPWKS-SPSATSGPWKSS 327
Cdd:PRK07764 540 VLGVRGDTLVLGFSTGGLARRfaspgnaevlvtalaeelggdwQVEAVVGPAPGAAGGEGPPAPASSgPPEEAARPAAPA 619
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 328 KPVQPMSPGPwkPIPSVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTSPESWKSGPPELRKTALPLSPEHWKAVPPVSPE 407
Cdd:PRK07764 620 APAAPAAPAP--AGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAA 697
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 148690223 408 LRRPGPPLSPEIRSPAGSPELKKPSSSPdlWKVSPDQRKTSPASLDFPEPQKSSCGSPP 466
Cdd:PRK07764 698 PAQPAPAPAATPPAGQADDPAAQPPQAA--QGASAPSPAADDPVPLPPEPDDPPDPAGA 754
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
108-417 |
3.47e-06 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 50.82 E-value: 3.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 108 SPSPPERQNPAFDPAEARPTPALPMEAQK-TSPSLCPESQASGPPVLEPQGAGPLISPEPQAPCLPAEASKAAPVPCPER 186
Cdd:PHA03377 604 KDGPPASGPHEKQPPSSAPRDMAPSVVRMfLRERLLEQSTGPKPKSFWEMRAGRDGSGIQQEPSSRRQPATQSTPPRPSW 683
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 187 VDPPCELPELEKPERGPSPESVKSALVSSKPPKHSSfadtgaAPSALSPESPVLATSpepwgpslsaspesrKPARTASP 266
Cdd:PHA03377 684 LPSVFVLPSVDAGRAQPSEESHLSSMSPTQPISHEE------QPRYEDPDDPLDLSL---------------HPDQAPPP 742
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 267 EPRKPSPAESpelwkpfpaiasEPRRPTpAVSPGSWKPGPPGSPRPWKSSPSAT----------SGPWKSSKPVQ----P 332
Cdd:PHA03377 743 SHQAPYSGHE------------EPQAQQ-APYPGYWEPRPPQAPYLGYQEPQAQgvqvssypgyAGPWGLRAQHPryrhS 809
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 333 MSPGPWKPIPSVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTSPESWKSGPPELRKTALPLSPEHWKAVPPVSPELRRPG 412
Cdd:PHA03377 810 WAYWSQYPGHGHPQGPWAPRPPHLPPQWDGSAGHGQDQVSQFPHLQSETGPPRLQLSQVPQLPYSQTLVSSSAPSWSSPQ 889
|
....*..
gi 148690223 413 P--PLSP 417
Cdd:PHA03377 890 PraPIRP 896
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
218-451 |
3.83e-06 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 50.85 E-value: 3.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 218 PKHSSFADTGAAPSALSPESPVLATSPEPWGPSLSASPESrkpARTASPEPRKPSP--AESPELWKPFPAIAseprRPTP 295
Cdd:PRK10263 319 PVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTV---AWQPVPGPQTGEPviAPAPEGYPQQSQYA----QPAV 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 296 AVSPGSWKPGPPGSPRPWKSSPSATSGPWKSSKPVQPMSPGPWKPIPS--VSPGPWKPAPSMSTASWKSSVSSGSWKTPP 373
Cdd:PRK10263 392 QYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEqpVAGNAWQAEEQQSTFAPQSTYQTEQTYQQP 471
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 374 TSPESWKSGPPelrktalPLSPEHWKAVPPVSPELRRPGPPL--------------------SPEIRSPAGSPELKKPSS 433
Cdd:PRK10263 472 AAQEPLYQQPQ-------PVEQQPVVEPEPVVEETKPARPPLyyfeeveekrarereqlaawYQPIPEPVKEPEPIKSSL 544
|
250
....*....|....*...
gi 148690223 434 SPDLWKVSPDQRKTSPAS 451
Cdd:PRK10263 545 KAPSVAAVPPVEAAAAVS 562
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
227-426 |
5.31e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.17 E-value: 5.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 227 GAAPSALSPESPVLATSP-----EPWGPSLSASPE---SRKPARTAS----PEPRKPSPAESPELWKPFPAIASEPRRPT 294
Cdd:PHA03307 708 GDLPVAGGREERVAAVRAvslvaRTVAPLVRYSPRrarARASAWDITdalfSNPSLVPAKLAEALALLEPAEPQRGAGSS 787
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 295 PAVSPGSWKPGPPGSPRPWKSSPSATSGPWKSSKPVQPMSPGPWKPIPSVSPGPWKPAPSMSTASWKSSVSSGSWKTPPT 374
Cdd:PHA03307 788 PPVRAEAAFRRPGRLRRSGPAADAASRTASKRKSRSHTPDGGSESSGPARPPGAAARPPPARSSESSKSKPAAAGGRARG 867
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 148690223 375 SPESWKSGPPELRKTALPLSPEHWKAVPPV--SPELRRPGPPLSPEIRSPAGSP 426
Cdd:PHA03307 868 KNGRRRPRPPEPRARPGAAAPPKAAAAAPPagAPAPRPRPAPRVKLGPMPPGGP 921
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
223-358 |
5.97e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 49.71 E-value: 5.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 223 FADTGAAPSALSPESpvlATSPEPWGPSLSASPEsrkPARTASPEPRKPSPAESPELWKPFPAIASEPRRPTPAVSPGSw 302
Cdd:PRK14951 364 FKPAAAAEAAAPAEK---KTPARPEAAAPAAAPV---AQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAA- 436
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 148690223 303 KPGPPGSPRPWKSSPSATSGPWKSSKPVQpMSPGPWKPIPSVSPGPWKPAPSMSTA 358
Cdd:PRK14951 437 APAAAPAAVALAPAPPAQAAPETVAIPVR-VAPEPAVASAAPAPAAAPAAARLTPT 491
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
96-449 |
6.11e-06 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 50.07 E-value: 6.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 96 KEQPSKDTESGKSPSPPErqnpafDPAEARPTPALPMEAQKTSPSLCPESQASGPPvlepQGAGPLISPEPQAPCLPAEA 175
Cdd:PTZ00449 495 KLAPIEEEDSDKHDEPPE------GPEASGLPPKAPGDKEGEEGEHEDSKESDEPK----EGGKPGETKEGEVGKKPGPA 564
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 176 SKAAPVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPpkhssfadtgaapsaLSPESPVLatspepwgPSLSASP 255
Cdd:PTZ00449 565 KEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRP---------------TRPKSPKL--------PELLDIP 621
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 256 ESrkPARTASPE-PRKPSPAESPelwkpfpaiaSEPRRPTPAVSPGSwkPGPPGSPRP----------WKSSPSATSGPW 324
Cdd:PTZ00449 622 KS--PKRPESPKsPKRPPPPQRP----------SSPERPEGPKIIKS--PKPPKSPKPpfdpkfkekfYDDYLDAAAKSK 687
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 325 KSSKPVQPMSPGPWKPIPSVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTSPESWKS------GPPELRKTALPLSPEHw 398
Cdd:PTZ00449 688 ETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQPddieffTPPEEERTFFHETPAD- 766
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 148690223 399 KAVPPVSPELRRpgpplSPEIRSPAGSPE--LKKPSSSPDLWKVSPDQRKTSP 449
Cdd:PTZ00449 767 TPLPDILAEEFK-----EEDIHAETGEPDeaMKRPDSPSEHEDKPPGDHPSLP 814
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
100-456 |
7.22e-06 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 49.57 E-value: 7.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 100 SKDTESGKSPSPPERQNPAFDPAEARpTPALPMEAQKTSPSLCPESQASGPPVLEPQgagpliSPEPQAPCLPAEASKAA 179
Cdd:pfam17823 88 AEHTPHGTDLSEPATREGAADGAASR-ALAAAASSSPSSAAQSLPAAIAALPSEAFS------APRAAACRANASAAPRA 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 180 PVPCPErvdppcelpeleKPERG-PSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLATSPEPWGPSLSASPESR 258
Cdd:pfam17823 161 AIAAAS------------APHAAsPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHPAAGTAL 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 259 KPARTASPEPRKPSPAESPELWKPFPAIASEPRrpTPAVSPGSWKPGPPGS--PRPWKSSPSATSgpwkSSKPVQPMSPG 336
Cdd:pfam17823 229 AAVGNSSPAAGTVTAAVGTVTPAALATLAAAAG--TVASAAGTINMGDPHArrLSPAKHMPSDTM----ARNPAAPMGAQ 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 337 PWKPIPSVSpgpwKPAPSMSTASWKSSVSSGSWKTPPTsPESWKSGPPELRKTALPLSPEHWKAVPPVSPELRrpgpplS 416
Cdd:pfam17823 303 AQGPIIQVS----TDQPVHNTAGEPTPSPSNTTLEPNT-PKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSM------I 371
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 148690223 417 PEIRspAGSPElKKPSSSPdlwkvsPDQRKTSPASLDFPE 456
Cdd:pfam17823 372 PEVE--ATSPT-TQPSPLL------PTQGAAGPGILLAPE 402
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
202-469 |
1.17e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 49.08 E-value: 1.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 202 GPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLATSPEPWGPSLSASpesRKPARTASPePRKPSPAESPE--- 278
Cdd:PRK07003 365 GGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAA---AAATRAEAP-PAAPAPPATADrgd 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 279 --LWKPFPAIASEPRRPTPAVSPGSWKPGPPGSPRPwksspsaTSGPWKSSKPVQPMSPGPW--KPIPSVSPGPWKPAPS 354
Cdd:PRK07003 441 daADGDAPVPAKANARASADSRCDERDAQPPADSGS-------ASAPASDAPPDAAFEPAPRaaAPSAATPAAVPDARAP 513
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 355 MSTASWKSSVSSGSWKTPPTSPESWKSGPPE-----------LRKTALPLSPEHWKAVPPvspelrRPGPPLSPEIRSPA 423
Cdd:PRK07003 514 AAASREDAPAAAAPPAPEARPPTPAAAAPAAraggaaaaldvLRNAGMRVSSDRGARAAA------AAKPAAAPAAAPKP 587
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 148690223 424 GSPELKKPSSSPDLWKVSPDQRKTSPAsldfPEPQKSSCGSPPDLW 469
Cdd:PRK07003 588 AAPRVAVQVPTPRARAATGDAPPNGAA----RAEQAAESRGAPPPW 629
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
143-322 |
1.59e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 48.69 E-value: 1.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 143 PESQASGPPVLEPQGAGPLISPEPQAPCLPAEASKAAPVPCPERVDPPCELPELEKPERGPSPESvkSALVSSKPPKHSS 222
Cdd:PRK07003 360 PAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAE--APPAAPAPPATAD 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 223 FADTGAAPSALSPESPVLATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPELW--KPFPAIASEPRRP-TPAVSP 299
Cdd:PRK07003 438 RGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRaaAPSAATPAAVPDArAPAAAS 517
|
170 180
....*....|....*....|...
gi 148690223 300 GSWKPGPPGSPRPWKSSPSATSG 322
Cdd:PRK07003 518 REDAPAAAAPPAPEARPPTPAAA 540
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
95-441 |
1.71e-05 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 48.37 E-value: 1.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 95 PKEQPSKDTESGKSP--SPPERQNPAFDPAEARPTPALPMEA-QKTSPSLCPESQASGPPVLEPQGAGP---LISPEPQA 168
Cdd:pfam05109 490 PSPSPRDNGTESKAPdmTSPTSAVTTPTPNATSPTPAVTTPTpNATSPTLGKTSPTSAVTTPTPNATSPtpaVTTPTPNA 569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 169 --PCL-PAEASKAAPVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLATSP- 244
Cdd:pfam05109 570 tiPTLgKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPs 649
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 245 ---EPWGPSLSASPESRKPARTASpeprKPSPAESPELWKPFPAIASEPRRPTPAVSPG--SWKPGPPGSP---RPWKSS 316
Cdd:pfam05109 650 sisETLSPSTSDNSTSHMPLLTSA----HPTGGENITQVTPASTSTHHVSTSSPAPRPGttSQASGPGNSStstKPGEVN 725
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 317 PSATSGPWKSSKPVQPmsPGPWKPIPSVSPGPWKpaPSMSTASWKSSVSSGSWKTPPTSPESWKSGPPELRKTALPLSPe 396
Cdd:pfam05109 726 VTKGTPPKNATSPQAP--SGQKTAVPTVTSTGGK--ANSTTGGKHTTGHGARTSTEPTTDYGGDSTTPRTRYNATTYLP- 800
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 148690223 397 hwkavPPVSPELRRPGPPLSPEIRSPAGSPELkKPSSSPDLWKVS 441
Cdd:pfam05109 801 -----PSTSSKLRPRWTFTSPPVTTAQATVPV-PPTSQPRFSNLS 839
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
118-280 |
1.90e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 48.17 E-value: 1.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 118 AFDPAEARPTPALpmeaqktspslcPESQASGPPVLEPQGAGPLISPE-PQAPCLPAEASKAAPVPCPERVDPPcelPEL 196
Cdd:PRK14951 363 AFKPAAAAEAAAP------------AEKKTPARPEAAAPAAAPVAQAAaAPAPAAAPAAAASAPAAPPAAAPPA---PVA 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 197 EKPERGPSPESVKSALVSSKPPKHSsfadtgaAPSALSPESPVLATSPEPwgpslsaSPESRKPARTASPEPRKPSPAES 276
Cdd:PRK14951 428 APAAAAPAAAPAAAPAAVALAPAPP-------AQAAPETVAIPVRVAPEP-------AVASAAPAPAAAPAAARLTPTEE 493
|
....
gi 148690223 277 PELW 280
Cdd:PRK14951 494 GDVW 497
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
235-565 |
2.19e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.40 E-value: 2.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 235 PESPVLATSPEPWGPSLS-ASPE---SRKPARTASPEPRKPSPA----------ESPELW---KPFPAIASE------PR 291
Cdd:PHA03247 2475 PGAPVYRRPAEARFPFAAgAAPDpggGGPPDPDAPPAPSRLAPAilpdepvgepVHPRMLtwiRGLEELASDdagdppPP 2554
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 292 RPTPAVSPGSWKPGPPGSPRPWKSSPSATSGPWKSSKPVQPMSPGPWKPIPSVSPGPWKPAPSmstaswKSSVSSGSWKT 371
Cdd:PHA03247 2555 LPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPL------PPDTHAPDPPP 2628
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 372 PPTSPESWKSGPPELRKTALPLSPEHWKAVPPVSPELRRPGPPLSPEIRSPAGSPelKKPSSSPDLWKVSPDQRKTSPAS 451
Cdd:PHA03247 2629 PSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRP--RRRAARPTVGSLTSLADPPPPPP 2706
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 452 LDFPEPQKSSCGSPPDLWKSSFIMESQKPNVFSETRkhtasGSSESPKVASDIWKPvlsidAEPRKSTLFPEPTKAVLPA 531
Cdd:PHA03247 2707 TPEPAPHALVSATPLPPGPAAARQASPALPAAPAPP-----AVPAGPATPGGPARP-----ARPPTTAGPPAPAPPAAPA 2776
|
330 340 350
....*....|....*....|....*....|....
gi 148690223 532 SPEPRKRALFPESRKHVFLPELPKSAVFSDAQKA 565
Cdd:PHA03247 2777 AGPPRRLTRPAVASLSESRESLPSPWDPADPPAA 2810
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
240-433 |
2.70e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 47.92 E-value: 2.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 240 LATSPEPWGPSLSASPESRKPARTA-SPEPRKPSPAESPELW--KPFPAIASEPRRPTPAVS-PGSWKPGPPGSPRPWKS 315
Cdd:PRK07003 356 LAFEPAVTGGGAPGGGVPARVAGAVpAPGARAAAAVGASAVPavTAVTGAAGAALAPKAAAAaAATRAEAPPAAPAPPAT 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 316 SPSATSgPWKSSKPVQPMSPGPWKPIPSVSPGPWKPAPSMSTAswkssvSSGSWKTPPTSPesWKSGPPELRKTALPLSP 395
Cdd:PRK07003 436 ADRGDD-AADGDAPVPAKANARASADSRCDERDAQPPADSGSA------SAPASDAPPDAA--FEPAPRAAAPSAATPAA 506
|
170 180 190
....*....|....*....|....*....|....*...
gi 148690223 396 EHWKAVPPVSPELRRPGPPLSPEIRSPAGSPELKKPSS 433
Cdd:PRK07003 507 VPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAA 544
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
94-342 |
2.71e-05 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 47.75 E-value: 2.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 94 QPKEQPSKDTESGKSPSPPERQNPA-FDPAEARPTPALPMEAQKT-------SPSLCPESQASgPPVLEPQGAGPLISPE 165
Cdd:PHA03378 668 QIGHIPYQPSPTGANTMLPIQWAPGtMQPPPRAPTPMRPPAAPPGraqrpaaATGRARPPAAA-PGRARPPAAAPGRARP 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 166 PQAPCLPAEASKAAPVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKHSsfadtGAAPSALSPESPVLATSPE 245
Cdd:PHA03378 747 PAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGAPTPQPPPQA-----GPTSMQLMPRAAPGQQGPT 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 246 PW-------GPSLSASPESRKPARTASPEPRKPSPAESPelwKPFPAIASEPRRPTPAVSPgSWKPGPPGSPRPWKSSpS 318
Cdd:PHA03378 822 KQilrqlltGGVKRGRPSLKKPAALERQAAAGPTPSPGS---GTSDKIVQAPVFYPPVLQP-IQVMRQLGSVRAAAAS-T 896
|
250 260
....*....|....*....|....
gi 148690223 319 ATSGPWKSSKPVQPMSPGPWKPIP 342
Cdd:PHA03378 897 VTQAPTEYTGERRGVGPMHPTDIP 920
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
94-342 |
3.02e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 47.54 E-value: 3.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 94 QPKEQPSKDTESGKSPSPPERQNPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAGPLISPEPQAPCLPA 173
Cdd:PRK07003 429 APAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVP 508
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 174 EASKAAPVPCPERVDPPCElpelekpergPSPESVKSALVSSKPPkhssfADTGAAPSALSpespVLATSpepwGPSLSa 253
Cdd:PRK07003 509 DARAPAAASREDAPAAAAP----------PAPEARPPTPAAAAPA-----ARAGGAAAALD----VLRNA----GMRVS- 564
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 254 SPESRKPARTASPePRKPSPAESPelwkpfpaiaSEPRRPTPAVSPGSWKPGPPGSPRPWKSSPSATSgpwksskpvQPM 333
Cdd:PRK07003 565 SDRGARAAAAAKP-AAAPAAAPKP----------AAPRVAVQVPTPRARAATGDAPPNGAARAEQAAE---------SRG 624
|
....*....
gi 148690223 334 SPGPWKPIP 342
Cdd:PRK07003 625 APPPWEDIP 633
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
174-451 |
3.30e-05 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 47.75 E-value: 3.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 174 EASKAAPVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKHSS-------FADTGAAPSALSPESPVLATSPep 246
Cdd:PHA03379 403 EALEKASEPTYGTPRPPVEKPRPEVPQSLETATSHGSAQVPEPPPVHDLepgplhdQHSMAPCPVAQLPPGPLQDLEP-- 480
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 247 wGPSLSASPESRKPARTASPEPRKP--SPAESPELWKPFPAIASE-----PRRPTPAVSPGSWKPGPPGSPRPWKSSPSA 319
Cdd:PHA03379 481 -GDQLPGVVQDGRPACAPVPAPAGPivRPWEASLSQVPGVAFAPVmpqpmPVEPVPVPTVALERPVCPAPPLIAMQGPGE 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 320 TSGPWKSSkpvQPMSPGPWKPIP--SVSPGPWKPAPSMSTASWKSSVSS---GSWKTPPTSPESWKSGPPELRKTALPLS 394
Cdd:PHA03379 560 TSGIVRVR---ERWRPAPWTPNPprSPSQMSVRDRLARLRAEAQPYQASvevQPPQLTQVSPQQPMEYPLEPEQQMFPGS 636
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 148690223 395 PEHWKA-------VPPVSPE-----LRRP---GPPLSPEIRSPAGSPelKKPSSSPDLWKVSPDQRKTSPAS 451
Cdd:PHA03379 637 PFSQVAdvmraggVPAMQPQyfdlpLQQPisqGAPLAPLRASMGPVP--PVPATQPQYFDIPLTEPINQGAS 706
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
103-354 |
3.51e-05 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 47.77 E-value: 3.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 103 TESGKSPSPPERQNPAFDPAEarPTPALPMEAQKTSPSLcpesqASGPPVLEPQGAGPLISPEPQAPCLPAEASKAAPVP 182
Cdd:PRK10263 330 TQSWAAPVEPVTQTPPVASVD--VPPAQPTVAWQPVPGP-----QTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQ 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 183 CPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLATSPEPW------GPSLSASPE 256
Cdd:PRK10263 403 PQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTyqqpaaQEPLYQQPQ 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 257 SRKPARTASPEP--RKPSPAESP-------------------ELWKPFPAIASEPRRPTPAVSPGSWKPGPPGSPRPW-- 313
Cdd:PRK10263 483 PVEQQPVVEPEPvvEETKPARPPlyyfeeveekrarereqlaAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAvs 562
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 148690223 314 ------KSSPSATSGPWKSSKPVQPMSPGPwKPIPSVSP--GPWKPAPS 354
Cdd:PRK10263 563 plasgvKKATLATGAAATVAAPVFSLANSG-GPRPQVKEgiGPQLPRPK 610
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
107-244 |
4.18e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 47.02 E-value: 4.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 107 KSPSPPERQNPAFDPAEARPTPALPMEAqktspslcPESQASGPPVLEPQGAGPLISPEPQAPCLPAEASKAAPVPCPEr 186
Cdd:PRK14951 379 KTPARPEAAAPAAAPVAQAAAAPAPAAA--------PAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAP- 449
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 148690223 187 VDPPCELPELEKPERGPSPEsvksalvsskppkhSSFADTGAAPSALSPESPVLATSP 244
Cdd:PRK14951 450 APPAQAAPETVAIPVRVAPE--------------PAVASAAPAPAAAPAAARLTPTEE 493
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
99-239 |
4.39e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 47.08 E-value: 4.39e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 99 PSKDTESGKSPSPPERQNPAF-DPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAGPLISPEPQAPclpaeask 177
Cdd:PRK14971 363 TQKGDDASGGRGPKQHIKPVFtQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAA-------- 434
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 148690223 178 aAPVPcPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKHssfaDTGAAPSALSPESPV 239
Cdd:PRK14971 435 -VPVN-PPSTAPQAVRPAQFKEEKKIPVSKVSSLGPSTLRPIQ----EKAEQATGNIKEAPT 490
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
120-271 |
6.80e-05 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 45.91 E-value: 6.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 120 DPAEARPTPALPmeaqkTSPSLCPESQASGPPVLEPQGAGPlisPEPQAPCLPAEASKAAPVPCPERVDPPCELPELEKP 199
Cdd:NF040712 189 DPDFGRPLRPLA-----TVPRLAREPADARPEEVEPAPAAE---GAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPV 260
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 148690223 200 ERGPSPESVksalvsskPPKHSSFADTGAAPSALSPESPVLATSPEPWGPSLSASPESRKPARTASPEPRKP 271
Cdd:NF040712 261 GPGAAPAAE--------PDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPAAPAAPEAEEPARPEPPPAPKP 324
|
|
| PHA03325 |
PHA03325 |
nuclear-egress-membrane-like protein; Provisional |
207-357 |
8.75e-05 |
|
nuclear-egress-membrane-like protein; Provisional
Pssm-ID: 223044 Cd Length: 418 Bit Score: 45.64 E-value: 8.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 207 SVKSALVSSKPPKHSSFADTGAAPSALSPESPVLATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPELWKPFPAI 286
Cdd:PHA03325 267 SLPTSAPKRRSRRAGAMRAAAGETADLADDDGSEHSDPEPLPASLPPPPVRRPRVKHPEAGKEEPDGARNAEAKEPAQPA 346
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 148690223 287 ASEPRRPTPAVSPGSWKPGPPGSPRPWKSSPSATsgPWKSSKPVQPMSPGPWKPIPSVSPGPWKPAPSMST 357
Cdd:PHA03325 347 TSTSSKGSSSAQNKDSGSTGPGSSLAAASSFLED--DDFGSPPLDLTTSLRHMPSPSVTSAPEPPSIPLTY 415
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
86-337 |
9.73e-05 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 46.22 E-value: 9.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 86 AASDKWSEQPKEQPSKDTESGKSPSPPERQNPAfdPAEARPTPAlpmeaqktspslcPESQASGPPVLEPQGAGPLISPE 165
Cdd:PTZ00449 523 APGDKEGEEGEHEDSKESDEPKEGGKPGETKEG--EVGKKPGPA-------------KEHKPSKIPTLSKKPEFPKDPKH 587
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 166 PQAPCLPAEASKAAPVPCPERVDPPcELPELEK-PERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPvlaTSP 244
Cdd:PTZ00449 588 PKDPEEPKKPKRPRSAQRPTRPKSP-KLPELLDiPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPP---KSP 663
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 245 E-PWGPSLSAS---PESRKPARTASPEprkpspaESPELWKPFPAIASEPRRPTPAVSPGSWKPGPPGSPRpwksSPSAT 320
Cdd:PTZ00449 664 KpPFDPKFKEKfydDYLDAAAKSKETK-------TTVVLDESFESILKETLPETPGTPFTTPRPLPPKLPR----DEEFP 732
|
250
....*....|....*..
gi 148690223 321 SGPwksskPVQPMSPGP 337
Cdd:PTZ00449 733 FEP-----IGDPDAEQP 744
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
115-374 |
1.14e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.08 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 115 QNPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAGPLISPEPQAPCLPAEAS--------KAAPVPCPER 186
Cdd:PHA03247 233 QDEPFVERRVVISHPLRGDIAAPAPPPVVGEGADRAPETARGATGPPPPPEAAAPNGAAAPPdgvwgaalAGAPLALPAP 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 187 VDPPCELPELEKPErgpSPESVKSALVSSKPPKHSSFADTGAA----PSALSPESPVLATSPEPWGPSLSASPESRKPAR 262
Cdd:PHA03247 313 PDPPPPAPAGDAEE---EDDEDGAMEVVSPLPRPRQHYPLGFPkrrrPTWTPPSSLEDLSAGRHHPKRASLPTRKRRSAR 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 263 -TASPEPRKPSPAESPElwkpfpaiasePRRPTPAVSPgswKPGPPGSPRPwksSPSATSGPWKSSKPVQPMSPG--PWK 339
Cdd:PHA03247 390 hAATPFARGPGGDDQTR-----------PAAPVPASVP---TPAPTPVPAS---APPPPATPLPSAEPGSDDGPAppPER 452
|
250 260 270
....*....|....*....|....*....|....*
gi 148690223 340 PIPSVSPGPWKPAPSMSTASWKSSVSSGSWKTPPT 374
Cdd:PHA03247 453 QPPAPATEPAPDDPDDATRKALDALRERRPPEPPG 487
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
203-535 |
1.41e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 45.53 E-value: 1.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 203 PSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPvlATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPELWKP 282
Cdd:pfam03154 177 QSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSP--ATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQ 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 283 FPAIASEPRRPTPavSPGSWKPGPPGsPRPWKSSPSATSGPwkssKPVQPMSPGPWKPIPSVSPGPWKPAPSMStaswks 362
Cdd:pfam03154 255 PPPPSQVSPQPLP--QPSLHGQMPPM-PHSLQTGPSHMQHP----VPPQPFPLTPQSSQSQVPPGPSPAAPGQS------ 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 363 svsSGSWKTPPTSPESWKSGPPelRKTALPLSPehwKAVPPVSPELRRPGPPLsPEIRSPAGSPELKKPSSSPDLWKVSP 442
Cdd:pfam03154 322 ---QQRIHTPPSQSQLQSQQPP--REQPLPPAP---LSMPHIKPPPTTPIPQL-PNPQSHKHPPHLSGPSPFQMNSNLPP 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 443 DQRKTSPASLDFPEPqKSSCGSPPDLWKSSFIMESQ--KPNVFSETRKHTASGSSESPKVASdiwKPVLSIDAEPRKSTL 520
Cdd:pfam03154 393 PPALKPLSSLSTHHP-PSAHPPPLQLMPQSQQLPPPpaQPPVLTQSQSLPPPAASHPPTSGL---HQVPSQSPFPQHPFV 468
|
330
....*....|....*
gi 148690223 521 FPEPTKAVLPASPEP 535
Cdd:pfam03154 469 PGGPPPITPPSGPPT 483
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
196-336 |
1.91e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.16 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 196 LEKPERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLATSPEPWGPSLSASPESRKPARTASPEPRKPSPAE 275
Cdd:PHA03307 775 LEPAEPQRGAGSSPPVRAEAAFRRPGRLRRSGPAADAASRTASKRKSRSHTPDGGSESSGPARPPGAAARPPPARSSESS 854
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 148690223 276 SPELWKPFPAIASEPRRPTPAVSPGSWKPG----PPGSPRPWKSSPSATSGPWKSSKPVQPMSPG 336
Cdd:PHA03307 855 KSKPAAAGGRARGKNGRRRPRPPEPRARPGaaapPKAAAAAPPAGAPAPRPRPAPRVKLGPMPPG 919
|
|
| TALPID3 |
pfam15324 |
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ... |
133-348 |
2.13e-04 |
|
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.
Pssm-ID: 434634 [Multi-domain] Cd Length: 1288 Bit Score: 44.88 E-value: 2.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 133 EAQKTSPSlcPESQASGPPVLEPQGAGPLISPEPQAPCLPAEASKAapvpcPERVDPPCELPELEKPERGPSPESVKSAL 212
Cdd:pfam15324 962 EAQREPPV--AASVPGDLPTKETLLPTPVPTPQPTPPCSPPSPLKE-----PSPVKTPDSSPCVSEHDFFPVKEIPPEKG 1034
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 213 VSSKPpkHSSFADTgaaPSALSPESPVLATSPEPwgpslsasPES-RKPARTASPEPRKPSPAESPELwkpfPAIASEPR 291
Cdd:pfam15324 1035 ADTGP--AVSLVIT---PTVTPIATPPPAATPTP--------PLSeNSIDKLKSPSPELPKPWEDSDL----PLEEENPN 1097
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 148690223 292 RPTPAVSPGSWKPGPPGSPRPWKSSPSATSgpwKSSKPVQPMSPGPWKPIPSVSPGP 348
Cdd:pfam15324 1098 SEQEELHPRAVVMSVARDEEPESVVLPASP---PEPKPLAPPPLGAAPPSPPQSPSS 1151
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
193-337 |
2.33e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 44.59 E-value: 2.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 193 LPELEKPERGpspesvksaLVSSKPPKHSSFADTGAAPSALSPESPvlATSPEPWGPSLSASPESRKPARTASPEPRKPS 272
Cdd:PRK07764 375 LARLERLERR---------LGVAGGAGAPAAAAPSAAAAAPAAAPA--PAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPS 443
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 148690223 273 PAESPelwkPFPAIASEPRRPTPAVSPGSWKPGPPGSPRPWKSSPSATSGPwkSSKPVQPMSPGP 337
Cdd:PRK07764 444 PAGNA----PAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAP--AAAPAAPAAPAA 502
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
107-332 |
2.46e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 44.93 E-value: 2.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 107 KSPSPPERQNPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPvlEPQGAGPLISPEPQApclpaeASKAAPVPCPeR 186
Cdd:PHA03247 274 GATGPPPPPEAAAPNGAAAPPDGVWGAALAGAPLALPAPPDPPPP--APAGDAEEEDDEDGA------MEVVSPLPRP-R 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 187 VDPPCELPELEKPERGPsPESVKSALVSSKPPKHSSFADTG--AAPSAlspespvlatspepwgpslsASPESRKPARTA 264
Cdd:PHA03247 345 QHYPLGFPKRRRPTWTP-PSSLEDLSAGRHHPKRASLPTRKrrSARHA--------------------ATPFARGPGGDD 403
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 148690223 265 SPEPRKPSPAESPElwkPFPAIASEPRRPTPAVSPGSWKPGPPGSPRPwkssPSATSGPWKSSKPVQP 332
Cdd:PHA03247 404 QTRPAAPVPASVPT---PAPTPVPASAPPPPATPLPSAEPGSDDGPAP----PPERQPPAPATEPAPD 464
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
217-466 |
2.46e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 44.76 E-value: 2.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 217 PPKHSSFADTGAAPSALSPESPVLATspePWGPSLSASPESRKPARTASPEPRKPSPAESPElwkPFPAIASEPRRPTPA 296
Cdd:pfam03154 151 PQDNESDSDSSAQQQILQTQPPVLQA---QSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQ---GSPATSQPPNQTQST 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 297 VSPGSW-------------KPGPPGSPRPWKSSPSATSG----PWKSSKPVQPMsPGPWKPIPSVSPGPWKPAPSmstas 359
Cdd:pfam03154 225 AAPHTLiqqtptlhpqrlpSPHPPLQPMTQPPPPSQVSPqplpQPSLHGQMPPM-PHSLQTGPSHMQHPVPPQPF----- 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 360 wkssvssgswktpPTSPESWKSGPPELRKTALPLSPEHWKAVPPVSPELRRPGPPL-SPEIRSPAGSPELKKPSSSPdLW 438
Cdd:pfam03154 299 -------------PLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPReQPLPPAPLSMPHIKPPPTTP-IP 364
|
250 260
....*....|....*....|....*...
gi 148690223 439 KVSPDQRKTSPASLDFPEPQKSSCGSPP 466
Cdd:pfam03154 365 QLPNPQSHKHPPHLSGPSPFQMNSNLPP 392
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
178-355 |
2.57e-04 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 44.43 E-value: 2.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 178 AAPVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPpkhsSFADTGAAPSAlSPESPVLATSPEP--W-GPSLSAS 254
Cdd:PRK14086 92 AGEPAPPPPHARRTSEPELPRPGRRPYEGYGGPRADDRPP----GLPRQDQLPTA-RPAYPAYQQRPEPgaWpRAADDYG 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 255 PESRKPARTASPEPRKPS-PAESPELWKPFPAIAS---EPRRPTPAVSPGSW---------KPGP-PGSPRPWKSSPSAT 320
Cdd:PRK14086 167 WQQQRLGFPPRAPYASPAsYAPEQERDREPYDAGRpeyDQRRRDYDHPRPDWdrprrdrtdRPEPpPGAGHVHRGGPGPP 246
|
170 180 190
....*....|....*....|....*....|....*
gi 148690223 321 SGPWKSSKPVQPMSPGPWKPIPSVSPGPWKPAPSM 355
Cdd:PRK14086 247 ERDDAPVVPIRPSAPGPLAAQPAPAPGPGEPTARL 281
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
172-324 |
2.64e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 44.32 E-value: 2.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 172 PAEASKAAPVPCPERVDPPcelpelEKPERGPSPESVKSALVSSKPPkhssfadtgaaPSALSPESPVLATSPEPwGPSL 251
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARP------EAAAPAAAPVAQAAAAPAPAAA-----------PAAAASAPAAPPAAAPP-APVA 427
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 148690223 252 SASPESRKPARTASPEPRKPSPAESPELWKPFPAIasePRRPTPAVSPGSWKPGPPGSPRPWKSSPSATSGPW 324
Cdd:PRK14951 428 APAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAI---PVRVAPEPAVASAAPAPAAAPAAARLTPTEEGDVW 497
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
253-435 |
3.21e-04 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 44.05 E-value: 3.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 253 ASPESRKPARTasPEPRKPSPAESPelWKPFPAIASEPRRPTPAVSPGSWKPgPPGSPrpwKSSPSATSGPWKSskpvqP 332
Cdd:PRK14086 95 PAPPPPHARRT--SEPELPRPGRRP--YEGYGGPRADDRPPGLPRQDQLPTA-RPAYP---AYQQRPEPGAWPR-----A 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 333 MSPGPWKPIPSVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTSPESWKSG--------PPELRKTALPLSPEHWKAVPPV 404
Cdd:PRK14086 162 ADDYGWQQQRLGFPPRAPYASPASYAPEQERDREPYDAGRPEYDQRRRDYdhprpdwdRPRRDRTDRPEPPPGAGHVHRG 241
|
170 180 190
....*....|....*....|....*....|.
gi 148690223 405 SPELRRPGPPLSPEIRSPAGSPELKKPSSSP 435
Cdd:PRK14086 242 GPGPPERDDAPVVPIRPSAPGPLAAQPAPAP 272
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
92-390 |
3.76e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 44.29 E-value: 3.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 92 SEQPKEQPSKDTESGKSPSP-PERQNPAFDPAEARPTPALPMEAQKTSPSLCPeSQASGPPV---LEPQGAGPLISPEPQ 167
Cdd:PHA03378 550 SDEPASTEPVHDQLLPAPGLgPLQIQPLTSPTTSQLASSAPSYAQTPWPVPHP-SQTPEPPTtqsHIPETSAPRQWPMPL 628
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 168 APcLPAEASKAAPVPCPERVDPpcelpeleKPERGPSPESVKSALVSSKPPkHSSFADTGAAPSALSPESPVLATS-PEP 246
Cdd:PHA03378 629 RP-IPMRPLRMQPITFNVLVFP--------TPHQPPQVEITPYKPTWTQIG-HIPYQPSPTGANTMLPIQWAPGTMqPPP 698
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 247 WGPSLSASPEsrkpartASPEPRKPsPAESPELWKPFPAIASEPRRPTPAVSPGSWKPGPPGSPRPWKSSPSATSGPWKS 326
Cdd:PHA03378 699 RAPTPMRPPA-------APPGRAQR-PAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAA 770
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 148690223 327 SKPVQPMSPGPWKPI----PSVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTS------PESWKSGPPELRKTA 390
Cdd:PHA03378 771 PGAPTPQPPPQAPPApqqrPRGAPTPQPPPQAGPTSMQLMPRAAPGQQGPTKQilrqllTGGVKRGRPSLKKPA 844
|
|
| GGN |
pfam15685 |
Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the ... |
95-466 |
4.03e-04 |
|
Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the maturation of sperm and is expressed virtually only in the testis. It is found to be associated with the intracellular membrane, binds with GGNBP1 and may be involved in vesicular trafficking.
Pssm-ID: 434857 [Multi-domain] Cd Length: 668 Bit Score: 43.99 E-value: 4.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 95 PKEQPSKDTESGKSPSPPERQNpafDPAEARPTPALPMEAQKTSPS---LCPESQASG------PPVLEPQGAGPLISPE 165
Cdd:pfam15685 163 PAPPPPTPLEPRKPPPLPPSDR---QPPNRGITPALATSATSPTDSqakHIAEGKTAGgacggaPPQAGEGEMARFAASE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 166 PQAPCLPAEASKAAPVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLATSPE 245
Cdd:pfam15685 240 SGLSLLCKVTFKSAAPLCPAAASGPLAAKASLGGGGGGGLFAASGAISCAEVLKQGPLAPGAARPLGEVPRAALETEGGE 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 246 PWGPSLSASPESRKP-ARTASPEPRKPSPAESPEL-WKPFPAIASEPRRPTPAvspgswkPGPPGSPRpwkSSPSATSGP 323
Cdd:pfam15685 320 GDGEGCSGGPAAPAShARALPPPAYTTFPGSKPKFdWVSPPDGPERHFRFNGA-------GGGIGAPR---RRAAALSGP 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 324 WKSSKPvqpmSPGPWKPIPsvspGPWKPAPSMstaswksSVSSGSWKTPPTSPESWKSGPPELRK-TALPLSPEHWKAVP 402
Cdd:pfam15685 390 WGSPPP----PPGKAHPIP----GPRRPAPAL-------LAPPMFIFPAPTNGEPVRPGPPAPQAlLPRPPPPTPPATPP 454
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 148690223 403 PVSPELrrPGPPLSPEIRSPAGSPELKKPSSSPDLWKVSPDQRKTSPASLDFPEPQKSSCGSPP 466
Cdd:pfam15685 455 PVPPPI--PQLPALQPMPLAAARPPTPRPCPGHGESALAPAPTAPLPPALAADQAPAPALAAAP 516
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
161-324 |
5.37e-04 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 43.22 E-value: 5.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 161 LISPEPQAPcLPAeaskAAPVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVL 240
Cdd:NF040712 187 LIDPDFGRP-LRP----LATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVG 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 241 ATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPElwkPFPAIASEPRRPTPAvspgswKPGPPGSPRPWKSSPSAT 320
Cdd:NF040712 262 PGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAP---AAPAAPAAPEAEEPA------RPEPPPAPKPKRRRRRAS 332
|
....
gi 148690223 321 SGPW 324
Cdd:NF040712 333 VPSW 336
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
83-279 |
5.96e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.44 E-value: 5.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 83 ARHAASDKWSEQPkeqPSKDTESGKSPSPPERQNPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAGPLI 162
Cdd:PRK07764 613 ARPAAPAAPAAPA---APAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAA 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 163 SPEPQAPCLPAEASKAAPVPCPERVDPPceLPELEKPERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPE---SPV 239
Cdd:PRK07764 690 PAAPAGAAPAQPAPAPAATPPAGQADDP--AAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPpapAPA 767
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 148690223 240 LATSPEPWGPSLSASPESrkpARTASPEPRKPSPAESPEL 279
Cdd:PRK07764 768 AAPAAAPPPSPPSEEEEM---AEDDAPSMDDEDRRDAEEV 804
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
165-435 |
6.14e-04 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 43.38 E-value: 6.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 165 EPQAPCLPAE------ASKAAPVPCPERVDPPCELPELEKPERGPSPESVKSalvsskPPKHSSfadtgAAPSALSP--- 235
Cdd:PLN03209 308 ETTAPLTPMEellakiPSQRVPPKESDAADGPKPVPTKPVTPEAPSPPIEEE------PPQPKA-----VVPRPLSPyta 376
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 236 -ESPVLATSPEPWGPSlsASPESRKPARTAS-PEPRKPSPAESPELWKPFPAIASEPRRPTPAVSPGSWKPG--PPGSPR 311
Cdd:PLN03209 377 yEDLKPPTSPIPTPPS--SSPASSKSVDAVAkPAEPDVVPSPGSASNVPEVEPAQVEAKKTRPLSPYARYEDlkPPTSPS 454
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 312 PwksSPSATSGPWKSSKPVQPMSPGpwKPIPSVSPGPWKPAPSMSTasWKSSVSSGSWKTPPTSPESWKSGPPELRKTAL 391
Cdd:PLN03209 455 P---TAPTGVSPSVSSTSSVPAVPD--TAPATAATDAAAPPPANMR--PLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTN 527
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 148690223 392 PLSPEHWKAVPPVSPELRRPGPPlSPEIRSPAGSPELKKPSSSP 435
Cdd:PLN03209 528 EVVKVGNSAPPTALADEQHHAQP-KPRPLSPYTMYEDLKPPTSP 570
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
93-426 |
9.06e-04 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 42.74 E-value: 9.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 93 EQPKEQPSKDTE------SGKSPSPPERQNPAFDP------------AEARPTPALPMEAQKTSPSLCPESQASGPPVle 154
Cdd:PHA03379 421 EKPRPEVPQSLEtatshgSAQVPEPPPVHDLEPGPlhdqhsmapcpvAQLPPGPLQDLEPGDQLPGVVQDGRPACAPV-- 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 155 PQGAGPLISPEPQAPCLPAEASKAAPVPCPERVDP-PCELPELEKPERgpsPESVKSALVSSKPPKHSSFADTGAAPSAL 233
Cdd:PHA03379 499 PAPAGPIVRPWEASLSQVPGVAFAPVMPQPMPVEPvPVPTVALERPVC---PAPPLIAMQGPGETSGIVRVRERWRPAPW 575
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 234 SPeSPVLATSPEPWGPSLSASPESRKPaRTASPEPRKPS----PAESPELWKPFPAIASEPRRPTPAVSPGSWKPGPPGS 309
Cdd:PHA03379 576 TP-NPPRSPSQMSVRDRLARLRAEAQP-YQASVEVQPPQltqvSPQQPMEYPLEPEQQMFPGSPFSQVADVMRAGGVPAM 653
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 310 PRPWKSSPsaTSGPWKSSKPVQPM--SPGPWKPIPSVSPgPWKPAPSMSTASWKSSVSSGSWKTPPTSPeswksgppelr 387
Cdd:PHA03379 654 QPQYFDLP--LQQPISQGAPLAPLraSMGPVPPVPATQP-QYFDIPLTEPINQGASAAHFLPQQPMEGP----------- 719
|
330 340 350
....*....|....*....|....*....|....*....
gi 148690223 388 ktalpLSPEHWKAVPPVSPELRRPGPPLSPEIRSPAGSP 426
Cdd:PHA03379 720 -----LVPERWMFQGATLSQSVRPGVAQSQYFDLPLTQP 753
|
|
| KAR9 |
pfam08580 |
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ... |
138-348 |
9.90e-04 |
|
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.
Pssm-ID: 430088 [Multi-domain] Cd Length: 684 Bit Score: 42.51 E-value: 9.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 138 SPSLCPESqasgPPVLEPQGAGPLISPEPQAPCLPAEASkaAPVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKP 217
Cdd:pfam08580 429 TPGSSPPS----SVIMTPVNKGSKTPSSRRGSSFDFGSS--SERVINSKLRRESKLPQIASTLKQTKRPSKIPRASPNHS 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 218 PKHSSFADTGAAPSALSPESPVLATSPEPwGPSLSASPESRKPARTASPEPRKPSPAESPelwKPFPAIASEPRRPTPAV 297
Cdd:pfam08580 503 GFLSTPSNTATSETPTPALRPPSRPQPPP-PGNRPRWNASTNTNDLDVGHNFKPLTLTTP---SPTPSRSSRSSSTLPPV 578
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 148690223 298 SPGSWKPGppGSPRPWKSSPSATSGPWKSSKPVQPMSPGPWKPIPSVSPGP 348
Cdd:pfam08580 579 SPLSRDKS--RSPAPTCRSVSRASRRRASRKPTRIGSPNSRTSLLDEPPYP 627
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
118-278 |
1.62e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 41.77 E-value: 1.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 118 AFDPAEARPTPALPMEAQKTSPSLCPESQASGP--PVLEPQGAGPLISPEPQAPCLPAEASKAAPVPCPERVDPPCELPE 195
Cdd:PRK07994 358 AFHPAAPLPEPEVPPQSAAPAASAQATAAPTAAvaPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATK 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 196 LEKPERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLATSPEPWGPSLSASPESRKPA--RTASPEPRKPSP 273
Cdd:PRK07994 438 AKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKAleHEKTPELAAKLA 517
|
....*
gi 148690223 274 AESPE 278
Cdd:PRK07994 518 AEAIE 522
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
87-426 |
1.67e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.06 E-value: 1.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 87 ASDKWSEQPKEQPSKDTESGKSPSPPERQNPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAGPLISPEP 166
Cdd:pfam03154 160 SSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHP 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 167 QAPCLPAEASKAAPVPCPERVDPPCELPELEKPERG-PSPESVKSAL------VSSKPPKHSSFADTGAAPSALSPESPV 239
Cdd:pfam03154 240 QRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMpPMPHSLQTGPshmqhpVPPQPFPLTPQSSQSQVPPGPSPAAPG 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 240 LATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPELWKPFPAIA--------SEPRRPTPAVSPGSWKPGP---PG 308
Cdd:pfam03154 320 QSQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPnpqshkhpPHLSGPSPFQMNSNLPPPPalkPL 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 309 SPRPWKSSPSATSGPWKSSKPVQPMSPGPWKP------------------------IPSVSP------GPWKPAPSMSTA 358
Cdd:pfam03154 400 SSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPpvltqsqslpppaashpptsglhqVPSQSPfpqhpfVPGGPPPITPPS 479
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 148690223 359 SWKSSVSSGSWKTPPTSPESWKSGPPELRKTALPLSPEHWKAVPPVSPELRRPGPPLSpeiRSPAGSP 426
Cdd:pfam03154 480 GPPTSTSSAMPGIQPPSSASVSSSGPVPAAVSCPLPPVQIKEEALDEAEEPESPPPPP---RSPSPEP 544
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
111-332 |
2.13e-03 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 41.73 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 111 PPERQNPAFDPAEARPTPALPMEAQKTSPSL--CPESQASGPPVLEPQGAGPLISPEPQA----PCLPAEASKAAPVPCP 184
Cdd:PRK14086 80 RPIRIAITVDPSAGEPAPPPPHARRTSEPELprPGRRPYEGYGGPRADDRPPGLPRQDQLptarPAYPAYQQRPEPGAWP 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 185 ERVDP-PCELPELEKPERGPSPESvksalvSSKPPKHSSFADtgaAPSALSPESPvlatspEPWGPSLSASPESRKPART 263
Cdd:PRK14086 160 RAADDyGWQQQRLGFPPRAPYASP------ASYAPEQERDRE---PYDAGRPEYD------QRRRDYDHPRPDWDRPRRD 224
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 148690223 264 ASPEPRKPSPAESPElwKPFPAIASEPRRPTPAVSPGSwkPGPPGSprpwksSPSATSGPWKSSKPVQP 332
Cdd:PRK14086 225 RTDRPEPPPGAGHVH--RGGPGPPERDDAPVVPIRPSA--PGPLAA------QPAPAPGPGEPTARLNP 283
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
225-325 |
2.22e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 41.47 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 225 DTGAAPSALSpESPVLATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPelwkpfpaiasEPRRPTPAVSPGSWKP 304
Cdd:PRK14954 377 DGGVAPSPAG-SPDVKKKAPEPDLPQPDRHPGPAKPEAPGARPAELPSPASAP-----------TPEQQPPVARSAPLPP 444
|
90 100
....*....|....*....|...
gi 148690223 305 GPPGSPRPWKS--SPSATSGPWK 325
Cdd:PRK14954 445 SPQASAPRNVAsgKPGVDLGSWQ 467
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
81-214 |
2.65e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.51 E-value: 2.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 81 ITARHAASDKWSEQPKEQPSKDTESGKSPSPPERQNPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAGP 160
Cdd:PRK07764 673 AGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPA 752
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 148690223 161 LISPEPQAPclPAEASKAAPVPCPERVDPPCELPELEKPERGPSPESVKSALVS 214
Cdd:PRK07764 753 GAPAQPPPP--PAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEV 804
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
227-338 |
2.75e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 41.20 E-value: 2.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 227 GAAPSALSPESPVL---ATSPEP--WGPSLSASPESRKPArTASPEPRKPSPAESPEL-WK---PFPAIASEPRRPTPAV 297
Cdd:PRK14959 378 ASAPSGSAAEGPASggaATIPTPgtQGPQGTAPAAGMTPS-SAAPATPAPSAAPSPRVpWDdapPAPPRSGIPPRPAPRM 456
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 148690223 298 SPGSWKPGPPGSPRPWKSSPSATSGPwKSSKPVQPMSPGPW 338
Cdd:PRK14959 457 PEASPVPGAPDSVASASDAPPTLGDP-SDTAEHTPSGPRTW 496
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
292-379 |
2.80e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 41.20 E-value: 2.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 292 RPTPAVSPGSWKP--GPPGSPRPwkSSPSATSGPWKSSKPVQPMSPGPWKP---IPSVSPGPWKPAPSMSTASWKSSVSS 366
Cdd:PRK14959 404 GPQGTAPAAGMTPssAAPATPAP--SAAPSPRVPWDDAPPAPPRSGIPPRPaprMPEASPVPGAPDSVASASDAPPTLGD 481
|
90
....*....|....*
gi 148690223 367 GSWKTP--PTSPESW 379
Cdd:PRK14959 482 PSDTAEhtPSGPRTW 496
|
|
| Pneumo_att_G |
pfam05539 |
Pneumovirinae attachment membrane glycoprotein G; |
96-271 |
3.13e-03 |
|
Pneumovirinae attachment membrane glycoprotein G;
Pssm-ID: 114270 [Multi-domain] Cd Length: 408 Bit Score: 40.80 E-value: 3.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 96 KEQPSKDTESGKSPSPPERQNPAFDPAEARPTPALPMEAQKTSPSLcpeSQASGPPVLEpQGAGPLISPEPQAPCLPAEA 175
Cdd:pfam05539 166 KEPKTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTATANQ---RLSSTEPVGT-QGTTTSSNPEPQTEPPPSQR 241
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 176 SK------AAPVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLATSPEPWGP 249
Cdd:pfam05539 242 GPsgspqhPPSTTSQDQSTTGDGQEHTQRRKTPPATSNRRSPHSTATPPPTTKRQETGRPTPRPTATTQSGSSPPHSSPP 321
|
170 180
....*....|....*....|..
gi 148690223 250 SLSASPESRKPARTASPEPRKP 271
Cdd:pfam05539 322 GVQANPTTQNLVDCKELDPPKP 343
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
281-577 |
3.32e-03 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 41.21 E-value: 3.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 281 KPFPAIASEP--RRPTPAVSPGSwKPGPPGSPRPwKSSPSATSGPWKSSK-PVQPMSPGPWKPIPSVSpgpwKPAPsmst 357
Cdd:PTZ00449 494 KKLAPIEEEDsdKHDEPPEGPEA-SGLPPKAPGD-KEGEEGEHEDSKESDePKEGGKPGETKEGEVGK----KPGP---- 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 358 ASWKSSVSSGSWKTPPTSPESWKS--GPPELRKTALPLSPEhwKAVPPVSPELrrpgPPLSPEIRSPAGSPELKKPSSSP 435
Cdd:PTZ00449 564 AKEHKPSKIPTLSKKPEFPKDPKHpkDPEEPKKPKRPRSAQ--RPTRPKSPKL----PELLDIPKSPKRPESPKSPKRPP 637
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 436 DLWKVSPDQRKTSPASLDFPEPQKSScgSPP------------DLWKSSFIMESQKPNVFSET----RKHTASGSSESPK 499
Cdd:PTZ00449 638 PPQRPSSPERPEGPKIIKSPKPPKSP--KPPfdpkfkekfyddYLDAAAKSKETKTTVVLDESfesiLKETLPETPGTPF 715
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 148690223 500 VASDIWKPVLsidaePRKSTLFPEPTKAVLPASPEPRKRALFPESrKHVFLPELPKSAVFSDAqkapeLSEEIQLEAV 577
Cdd:PTZ00449 716 TTPRPLPPKL-----PRDEEFPFEPIGDPDAEQPDDIEFFTPPEE-ERTFFHETPADTPLPDI-----LAEEFKEEDI 782
|
|
| PLN02217 |
PLN02217 |
probable pectinesterase/pectinesterase inhibitor |
204-289 |
3.79e-03 |
|
probable pectinesterase/pectinesterase inhibitor
Pssm-ID: 215130 [Multi-domain] Cd Length: 670 Bit Score: 40.84 E-value: 3.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 204 SPESVKSALVSSKPPKHSSFADTGAAPS---ALSPESPVLATSPEPwgPSLSASPESRKPARTASPEPRKPSPAESPELW 280
Cdd:PLN02217 565 NPGSTNSTPTGSAASSNTTFSSDSPSTVvapSTSPPAGHLGSPPAT--PSKIVSPSTSPPASHLGSPSTTPSSPESSIKV 642
|
....*....
gi 148690223 281 KPFPAIASE 289
Cdd:PLN02217 643 ASTETASPE 651
|
|
| PHA03321 |
PHA03321 |
tegument protein VP11/12; Provisional |
92-323 |
4.81e-03 |
|
tegument protein VP11/12; Provisional
Pssm-ID: 223041 [Multi-domain] Cd Length: 694 Bit Score: 40.33 E-value: 4.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 92 SEQPKEQPSkdTESGKSPSPPERQNPAFDPAEARPTpalpmEAQKTSPSLCPESQASGPPVLEPQGAGPliSPEPQAPCL 171
Cdd:PHA03321 427 SRQPPGAPA--PRRDNDPPPPPRARPGSTPACARRA-----RAQRARDAGPEYVDPLGALRRLPAGAAP--PPEPAAAPS 497
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 172 PAEASKAAPVPCPeRVDPPCELPELEKPERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLATSPEPWGPSL 251
Cdd:PHA03321 498 PATYYTRMGGGPP-RLPPRNRATETLRPDWGPPAAAPPEQMEDPYLEPDDDRFDRRDGAAAAATSHPREAPAPDDDPIYE 576
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 148690223 252 SASpESRKPARTASPEPR-KPSPAESPELWKPFPAIASEPRRP-TPAVSP-GSWKPGPPGSPRPWKSSPSATSGP 323
Cdd:PHA03321 577 GVS-DSEEPVYEEIPTPRvYQNPLPRPMEGAGEPPDLDAPTSPwVEEENPiYGWGDSPLFSPPPAARFPPPDPAL 650
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
152-458 |
4.82e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 40.44 E-value: 4.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 152 VLEPQGAGPLISPEPQAPclpaEASKAAPVPCPERVD-----PPCELPELEKPERGPSPESVKSALVSSKPPKHSSfadt 226
Cdd:PHA03378 515 DMEQRVMATLLPPSPPQP----RAGRRAPCVYTEDLDiesdePASTEPVHDQLLPAPGLGPLQIQPLTSPTTSQLA---- 586
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 227 GAAPSALSPESPVLATSPEPWGPSLSA-SPESRKPARTasPEPRKPSPAESPELWkpfPAIASEPRRPTPAVSPgswKPG 305
Cdd:PHA03378 587 SSAPSYAQTPWPVPHPSQTPEPPTTQShIPETSAPRQW--PMPLRPIPMRPLRMQ---PITFNVLVFPTPHQPP---QVE 658
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 306 PPGSPRPWKSSPSAtsgpwksskPVQPMSPGPWKPIP-SVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTSPESWKSGPP 384
Cdd:PHA03378 659 ITPYKPTWTQIGHI---------PYQPSPTGANTMLPiQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAA 729
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 148690223 385 ELRKTALPLSPEHWKAVPPVSPELRRPGPPLSPEIRSPAGSPELKKPSSSPDLWKVSPDQRKTSPASLdfPEPQ 458
Cdd:PHA03378 730 APGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGAPTPQ--PPPQ 801
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
281-438 |
5.14e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 40.47 E-value: 5.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 281 KPFPAIASEPRRPTPAvspgswkPGPPGSPRPWKSSPSATSGPWKSSKPVQPMSPGPWKPIPSVSPGPwKPAPSMSTASW 360
Cdd:PRK14951 365 KPAAAAEAAAPAEKKT-------PARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAP-VAAPAAAAPAA 436
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 148690223 361 KSSVSSGSWKTPPTSPEswksgppelrktalPLSPEHWKAVPPVSPElrrPGPPLSPEIRSPAGSPELKKPSSSPDLW 438
Cdd:PRK14951 437 APAAAPAAVALAPAPPA--------------QAAPETVAIPVRVAPE---PAVASAAPAPAAAPAAARLTPTEEGDVW 497
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
284-546 |
5.20e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 40.45 E-value: 5.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 284 PAIASEPRRPTPAVSPGS------WKPGP-PGSPRP--------------WKSSPSATSGPWKsskpvQPMSPGPWKPIP 342
Cdd:PRK10263 336 PVEPVTQTPPVASVDVPPaqptvaWQPVPgPQTGEPviapapegypqqsqYAQPAVQYNEPLQ-----QPVQPQQPYYAP 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 343 SVSPGPWKPAPSMSTASWKSSVSSGSWKTPPTSPESWKSGPPELRKTALPLSPEHWKAVPPVSPELRRPGPPLSPEIRSP 422
Cdd:PRK10263 411 AAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVV 490
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 423 AGSPELK--KPSSSPDLWKVSPDQRKTS------------PASLDFPEPQKSSCgSPPDLWKSSFIMESQKPNVFSETRK 488
Cdd:PRK10263 491 EPEPVVEetKPARPPLYYFEEVEEKRARereqlaawyqpiPEPVKEPEPIKSSL-KAPSVAAVPPVEAAAAVSPLASGVK 569
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 148690223 489 HTASGSSESPKVASDIWKPVLSidAEPRkstlfPEPTKAVLPASPEPrKRALFPESRK 546
Cdd:PRK10263 570 KATLATGAAATVAAPVFSLANS--GGPR-----PQVKEGIGPQLPRP-KRIRVPTRRE 619
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
236-467 |
6.70e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 40.31 E-value: 6.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 236 ESPVLATSPEPWGPSLSASPESRKPARTASPEPRKPSPAESPelwKPFPAIASEPRRPTPAVSPGSWKPGPPGSPRPWKS 315
Cdd:PHA03247 239 ERRVVISHPLRGDIAAPAPPPVVGEGADRAPETARGATGPPP---PPEAAAPNGAAAPPDGVWGAALAGAPLALPAPPDP 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 316 SPSATSGPWKSS----KPVQPMSPGPwKPIPSVSPG-------PWKPAPSMSTASWKSSVSSGSWKTPPTSPESWKSGPP 384
Cdd:PHA03247 316 PPPAPAGDAEEEddedGAMEVVSPLP-RPRQHYPLGfpkrrrpTWTPPSSLEDLSAGRHHPKRASLPTRKRRSARHAATP 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 385 ELRKTALPLSPEHWKAVPPVSPElrrPGPPLSPEIRSPAgsPELKKPSSSPDlwkvsPDQRKTSPASLDFPEPQKSSCGS 464
Cdd:PHA03247 395 FARGPGGDDQTRPAAPVPASVPT---PAPTPVPASAPPP--PATPLPSAEPG-----SDDGPAPPPERQPPAPATEPAPD 464
|
...
gi 148690223 465 PPD 467
Cdd:PHA03247 465 DPD 467
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
93-280 |
6.92e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 40.08 E-value: 6.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 93 EQPKEQPSKDTESGKSPSPPERQNPAFDPAEARPTPALPMEAqKTSPSLCPESQASGPP-------VLEPQGAGPLISPE 165
Cdd:PRK08691 378 QSPSAQTAEKETAAKKPQPRPEAETAQTPVQTASAAAMPSEG-KTAGPVSNQENNDVPPwedapdeAQTAAGTAQTSAKS 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 166 PQApclPAEASKAAP--VPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPV---L 240
Cdd:PRK08691 457 IQT---ASEAETPPEnqVSKNKAADNETDAPLSEVPSENPIQATPNDEAVETETFAHEAPAEPFYGYGFPDNDCPPedgA 533
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 148690223 241 ATSPEPW---GPSLSASPESRKPARTAS----PEPRKPSPAESPELW 280
Cdd:PRK08691 534 EIPPPDWehaAPADTAGGGADEEAEAGGiggnNTPSAPPPEFSTENW 580
|
|
| PRK12495 |
PRK12495 |
hypothetical protein; Provisional |
82-172 |
7.16e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 183558 [Multi-domain] Cd Length: 226 Bit Score: 38.70 E-value: 7.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 82 TARHAASDKWSEQPKEQPskDTESGKSPSPPERQNPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAGPL 161
Cdd:PRK12495 85 TAPSDAGSQASPDDDAQP--AAEAEAADQSAPPEASSTSATDEAATDPPATAAARDGPTPDPTAQPATPDERRSPRQRPP 162
|
90
....*....|.
gi 148690223 162 ISPEPQAPCLP 172
Cdd:PRK12495 163 VSGEPPTPSTP 173
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
179-281 |
8.11e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 39.79 E-value: 8.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 179 APVPCPERVDPPCELPELEKPERGPS--PESVKSALVSSKPPKHSSfadtgaAPSALSPESPVlATSPEPWGPSLSASPE 256
Cdd:PRK14950 361 VPVPAPQPAKPTAAAPSPVRPTPAPStrPKAAAAANIPPKEPVRET------ATPPPVPPRPV-APPVPHTPESAPKLTR 433
|
90 100
....*....|....*....|....*
gi 148690223 257 SRKPARTAspePRKPSPAESPELWK 281
Cdd:PRK14950 434 AAIPVDEK---PKYTPPAPPKEEEK 455
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
175-332 |
9.39e-03 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 39.33 E-value: 9.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 175 ASKAAPVPCPE-RVDPPCELPElekpergPSPESVKSAlvSSKPpkhssfaDTGAAPSALSPESPVLATSPEPwgpslsA 253
Cdd:PHA03269 20 ANLNTNIPIPElHTSAATQKPD-------PAPAPHQAA--SRAP-------DPAVAPTSAASRKPDLAQAPTP------A 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 254 SPESRKPA-RTASPEPRKPSPAESPELwkpfpaiaSEPRRPTPAVSPGSWKPGPPGSPRPWKSSPSATSGPWKSSKPVQP 332
Cdd:PHA03269 78 ASEKFDPApAPHQAASRAPDPAVAPQL--------AAAPKPDAAEAFTSAAQAHEAPADAGTSAASKKPDPAAHTQHSPP 149
|
|
| MISS |
pfam15822 |
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic ... |
176-351 |
9.46e-03 |
|
MAPK-interacting and spindle-stabilising protein-like; MISS is a family of eukaryotic MAPK-interacting and spindle-stabilising protein-like proteins. MISS is rich in prolines and has four potential MAPK-phosphorylation sites, a MAPK-docking site, a PEST sequence (PEST motif) and a bipartite nuclear localization signal. The endogenous protein accumulates during mouse meiotic maturation and is found as discrete dots on the MII spindle. MISS is the first example of a physiological MAPK-substrate that is stabilized in MII that specifically regulates MII spindle integrity during the CSF arrest.
Pssm-ID: 318115 [Multi-domain] Cd Length: 238 Bit Score: 38.43 E-value: 9.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 176 SKAAPVPCPERVDPPCELPELEKPERGPSPESVKSALVSSKPPKHSSFadtGAAPSALSPESPVLATSPEPWGPSLSASP 255
Cdd:pfam15822 13 AKTSAVSNPKPGQPPQGWPGSNPWNNPSAPPAVPSGLPPSTAPSTVPF---GPAPTGMYPSIPLTGPSPGPPAPFPPSGP 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 256 ESRKPA------RTASPEPRKPSPAES---PELWKPFPA----IASEPRRPTPAVSPGSWKPGPpGSPRPWKSSPSATSG 322
Cdd:pfam15822 90 SCPPPGgpypapTVPGPGPIGPYPTPNmpfPELPRPYGAptdpAAAAPSGPWGSMSSGPWAPGM-GGQYPAPNMPYPSPG 168
|
170 180
....*....|....*....|....*....
gi 148690223 323 PWKSSKPVQPMSPGPWKPIPSVSPGPWKP 351
Cdd:pfam15822 169 PYPAVPPPQSPGAAPPVPWGTVPPGPWGP 197
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
108-241 |
9.85e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 39.47 E-value: 9.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148690223 108 SPSPPERQNPAFDPAEARPTPALPMEAQKTSPSLCPESQASGPPVLEPQGAGPLISPEPQAPCLPAEAskAAPVPCPERV 187
Cdd:PRK12323 455 AAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWV--AESIPDPATA 532
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 148690223 188 DPPCELPELeKPERGPSPESVKSALVSSKPPKHSSFADTGAAPSALSPESPVLA 241
Cdd:PRK12323 533 DPDDAFETL-APAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALA 585
|
|
| |
