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Conserved domains on  [gi|119621381|gb|EAX00976|]
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TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa, isoform CRA_c [Homo sapiens]

Protein Classification

TFIIB-type zinc finger domain-containing protein( domain architecture ID 10570348)

TFIIB-type zinc finger domain-containing protein similar to RRN7/TAF1B family proteins such as human TATA box-binding protein-associated factor RNA polymerase I subunit B (TAF1B) and Schizosaccharomyces pombe RNA polymerase I-specific transcription initiation factor rrn7

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-RRN7 pfam11781
Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7; This is the zinc-finger at the start of ...
 7-39 5.15e-08

Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7; This is the zinc-finger at the start of transcription-binding factor that associates strongly with both Rrn6 and Rrn7 to form a complex which itself binds the TATA-binding protein and is required for transcription by the core domain of the RNA PolI promoter.


:

Pssm-ID: 463348  Cd Length: 32  Bit Score: 48.74  E-value: 5.15e-08
                          10        20        30
                  ....*....|....*....|....*....|...
gi 119621381    7 EEFKERCTQCAAVSWGLtDEGKYYCTSCHNVTE 39
Cdd:pfam11781   1 WEKGPPCGVCGCRLFYL-DDGFYYCRRCHTQEG 32
 
Name Accession Description Interval E-value
zf-RRN7 pfam11781
Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7; This is the zinc-finger at the start of ...
 7-39 5.15e-08

Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7; This is the zinc-finger at the start of transcription-binding factor that associates strongly with both Rrn6 and Rrn7 to form a complex which itself binds the TATA-binding protein and is required for transcription by the core domain of the RNA PolI promoter.


Pssm-ID: 463348  Cd Length: 32  Bit Score: 48.74  E-value: 5.15e-08
                          10        20        30
                  ....*....|....*....|....*....|...
gi 119621381    7 EEFKERCTQCAAVSWGLtDEGKYYCTSCHNVTE 39
Cdd:pfam11781   1 WEKGPPCGVCGCRLFYL-DDGFYYCRRCHTQEG 32
 
Name Accession Description Interval E-value
zf-RRN7 pfam11781
Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7; This is the zinc-finger at the start of ...
 7-39 5.15e-08

Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7; This is the zinc-finger at the start of transcription-binding factor that associates strongly with both Rrn6 and Rrn7 to form a complex which itself binds the TATA-binding protein and is required for transcription by the core domain of the RNA PolI promoter.


Pssm-ID: 463348  Cd Length: 32  Bit Score: 48.74  E-value: 5.15e-08
                          10        20        30
                  ....*....|....*....|....*....|...
gi 119621381    7 EEFKERCTQCAAVSWGLtDEGKYYCTSCHNVTE 39
Cdd:pfam11781   1 WEKGPPCGVCGCRLFYL-DDGFYYCRRCHTQEG 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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