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Conserved domains on  [gi|119620517|gb|EAX00112|]
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hypothetical protein FLJ31438, isoform CRA_b [Homo sapiens]

Protein Classification

clathrin heavy chain( domain architecture ID 11239040)

clathrin heavy chain is a component of clathrin, the major protein of the polyhedral coat of coated pits and vesicles

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TSNAXIP1_N pfam15739
Translin-associated factor X-interacting N-terminus; This domain is found at the N-terminus of ...
 28-141 4.84e-29

Translin-associated factor X-interacting N-terminus; This domain is found at the N-terminus of translin-associated factor X-interacting protein, a protein which may play a role in spermatogenesis.


:

Pssm-ID: 464835 [Multi-domain]  Cd Length: 111  Bit Score: 111.16  E-value: 4.84e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620517   28 QRYIITETERLGCSEEGPADEYYIIYRNVFDKVIEHITAYKSILTSIKKEYDAFIETIKKDRRTTFCLHGKLKGLAAEPT 107
Cdd:pfam15739   1 ERKLEQELQKLGCTEDGPQELRLQVYREVFEDLIEHFTTYKPLLSEIKNEYELYIAHLLESQRELQYLKAKLKGLSEQSD 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 119620517  108 alvyyrKRTIQLEAK---MRIIESNSSKIQSQIDHIK 141
Cdd:pfam15739  81 ------KRALELEEKreeIRALEKESKALLERNDKLR 111
Clathrin_H_link pfam13838
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins ...
 297-354 4.37e-12

Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins directly downstream from the Clathrin-link domain pfam09268.


:

Pssm-ID: 463995  Cd Length: 66  Bit Score: 61.46  E-value: 4.37e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 119620517  297 YIERFNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEAL 354
Cdd:pfam13838   9 YFQQFNQLLNQGDYAEAAKVAANSPRGALRTPETIQRFKQLPAQPGQLSPILQYFGTL 66
 
Name Accession Description Interval E-value
TSNAXIP1_N pfam15739
Translin-associated factor X-interacting N-terminus; This domain is found at the N-terminus of ...
 28-141 4.84e-29

Translin-associated factor X-interacting N-terminus; This domain is found at the N-terminus of translin-associated factor X-interacting protein, a protein which may play a role in spermatogenesis.


Pssm-ID: 464835 [Multi-domain]  Cd Length: 111  Bit Score: 111.16  E-value: 4.84e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620517   28 QRYIITETERLGCSEEGPADEYYIIYRNVFDKVIEHITAYKSILTSIKKEYDAFIETIKKDRRTTFCLHGKLKGLAAEPT 107
Cdd:pfam15739   1 ERKLEQELQKLGCTEDGPQELRLQVYREVFEDLIEHFTTYKPLLSEIKNEYELYIAHLLESQRELQYLKAKLKGLSEQSD 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 119620517  108 alvyyrKRTIQLEAK---MRIIESNSSKIQSQIDHIK 141
Cdd:pfam15739  81 ------KRALELEEKreeIRALEKESKALLERNDKLR 111
Clathrin_H_link pfam13838
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins ...
 297-354 4.37e-12

Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins directly downstream from the Clathrin-link domain pfam09268.


Pssm-ID: 463995  Cd Length: 66  Bit Score: 61.46  E-value: 4.37e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 119620517  297 YIERFNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEAL 354
Cdd:pfam13838   9 YFQQFNQLLNQGDYAEAAKVAANSPRGALRTPETIQRFKQLPAQPGQLSPILQYFGTL 66
 
Name Accession Description Interval E-value
TSNAXIP1_N pfam15739
Translin-associated factor X-interacting N-terminus; This domain is found at the N-terminus of ...
 28-141 4.84e-29

Translin-associated factor X-interacting N-terminus; This domain is found at the N-terminus of translin-associated factor X-interacting protein, a protein which may play a role in spermatogenesis.


Pssm-ID: 464835 [Multi-domain]  Cd Length: 111  Bit Score: 111.16  E-value: 4.84e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620517   28 QRYIITETERLGCSEEGPADEYYIIYRNVFDKVIEHITAYKSILTSIKKEYDAFIETIKKDRRTTFCLHGKLKGLAAEPT 107
Cdd:pfam15739   1 ERKLEQELQKLGCTEDGPQELRLQVYREVFEDLIEHFTTYKPLLSEIKNEYELYIAHLLESQRELQYLKAKLKGLSEQSD 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 119620517  108 alvyyrKRTIQLEAK---MRIIESNSSKIQSQIDHIK 141
Cdd:pfam15739  81 ------KRALELEEKreeIRALEKESKALLERNDKLR 111
Clathrin_H_link pfam13838
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins ...
 297-354 4.37e-12

Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins directly downstream from the Clathrin-link domain pfam09268.


Pssm-ID: 463995  Cd Length: 66  Bit Score: 61.46  E-value: 4.37e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 119620517  297 YIERFNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEAL 354
Cdd:pfam13838   9 YFQQFNQLLNQGDYAEAAKVAANSPRGALRTPETIQRFKQLPAQPGQLSPILQYFGTL 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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