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Conserved domains on  [gi|119620262|gb|EAW99856|]
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anthrax toxin receptor 1, isoform CRA_b, partial [Homo sapiens]

Protein Classification

anthrax toxin receptor( domain architecture ID 10527794)

anthrax toxin receptor is the cellular receptor for the anthrax protective antigen and facilitates entry of the toxin into cells

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ant_C pfam05586
Anthrax receptor C-terminus region; This region is found in the putatively cytoplasmic ...
 106-198 2.18e-65

Anthrax receptor C-terminus region; This region is found in the putatively cytoplasmic C-terminus of the anthrax receptor.


:

Pssm-ID: 461683  Cd Length: 93  Bit Score: 198.68  E-value: 2.18e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620262  106 VRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQP 185
Cdd:pfam05586   1 VRWGEKGSTEEGAKLEKAKNAVVKMPEEEEEPPEPRPRKPPARKPPPQRKWYTPIKGKLDALWALLRRGYDRVSLMRPTP 80

                          90
                  ....*....|...
gi 119620262  186 GDTGRCINFTRVK 198
Cdd:pfam05586  81 GDKGRCINFTRVK 93
Anth_Ig super family cl05254
Anthrax receptor extracellular domain; This region is found in the putatively extracellular ...
 5-29 3.68e-09

Anthrax receptor extracellular domain; This region is found in the putatively extracellular N-terminal half of the anthrax receptor. It is probably part of the Ig superfamily and most closely related to pfam01833 (personal obs: C Yeats).


The actual alignment was detected with superfamily member pfam05587:

Pssm-ID: 461684  Cd Length: 102  Bit Score: 53.02  E-value: 3.68e-09
                          10        20
                  ....*....|....*....|....*
gi 119620262    5 LQVSMNDGLSFISSSVIITTTHCSD 29
Cdd:pfam05587  78 VLVSLNNGKSFISSSLTITATTCSD 102
 
Name Accession Description Interval E-value
Ant_C pfam05586
Anthrax receptor C-terminus region; This region is found in the putatively cytoplasmic ...
 106-198 2.18e-65

Anthrax receptor C-terminus region; This region is found in the putatively cytoplasmic C-terminus of the anthrax receptor.


Pssm-ID: 461683  Cd Length: 93  Bit Score: 198.68  E-value: 2.18e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620262  106 VRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQP 185
Cdd:pfam05586   1 VRWGEKGSTEEGAKLEKAKNAVVKMPEEEEEPPEPRPRKPPARKPPPQRKWYTPIKGKLDALWALLRRGYDRVSLMRPTP 80

                          90
                  ....*....|...
gi 119620262  186 GDTGRCINFTRVK 198
Cdd:pfam05586  81 GDKGRCINFTRVK 93
Anth_Ig pfam05587
Anthrax receptor extracellular domain; This region is found in the putatively extracellular ...
 5-29 3.68e-09

Anthrax receptor extracellular domain; This region is found in the putatively extracellular N-terminal half of the anthrax receptor. It is probably part of the Ig superfamily and most closely related to pfam01833 (personal obs: C Yeats).


Pssm-ID: 461684  Cd Length: 102  Bit Score: 53.02  E-value: 3.68e-09
                          10        20
                  ....*....|....*....|....*
gi 119620262    5 LQVSMNDGLSFISSSVIITTTHCSD 29
Cdd:pfam05587  78 VLVSLNNGKSFISSSLTITATTCSD 102
 
Name Accession Description Interval E-value
Ant_C pfam05586
Anthrax receptor C-terminus region; This region is found in the putatively cytoplasmic ...
 106-198 2.18e-65

Anthrax receptor C-terminus region; This region is found in the putatively cytoplasmic C-terminus of the anthrax receptor.


Pssm-ID: 461683  Cd Length: 93  Bit Score: 198.68  E-value: 2.18e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119620262  106 VRWGEKGSTEEGAKLEKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQP 185
Cdd:pfam05586   1 VRWGEKGSTEEGAKLEKAKNAVVKMPEEEEEPPEPRPRKPPARKPPPQRKWYTPIKGKLDALWALLRRGYDRVSLMRPTP 80

                          90
                  ....*....|...
gi 119620262  186 GDTGRCINFTRVK 198
Cdd:pfam05586  81 GDKGRCINFTRVK 93
Anth_Ig pfam05587
Anthrax receptor extracellular domain; This region is found in the putatively extracellular ...
 5-29 3.68e-09

Anthrax receptor extracellular domain; This region is found in the putatively extracellular N-terminal half of the anthrax receptor. It is probably part of the Ig superfamily and most closely related to pfam01833 (personal obs: C Yeats).


Pssm-ID: 461684  Cd Length: 102  Bit Score: 53.02  E-value: 3.68e-09
                          10        20
                  ....*....|....*....|....*
gi 119620262    5 LQVSMNDGLSFISSSVIITTTHCSD 29
Cdd:pfam05587  78 VLVSLNNGKSFISSSLTITATTCSD 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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