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Conserved domains on  [gi|119618810|gb|EAW98404|]
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sno, strawberry notch homolog 1 (Drosophila), isoform CRA_c, partial [Homo sapiens]

Protein Classification

strawberry notch family protein( domain architecture ID 1001901)

strawberry notch (SBNO) family protein may participate with members of the Notch pathway in facilitating developmentally relevant cell-cell communications; belongs to the DEAD/DEAH box helicase superfamily

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Helicase_C_4 super family cl24266
C-terminal domain on Strawberry notch homolog; Strawberry notch proteins carry DExD/H-box ...
 209-270 9.76e-33

C-terminal domain on Strawberry notch homolog; Strawberry notch proteins carry DExD/H-box groups upstream of this domain. The function of this domain is not known. These proteins promote the expression of diverse targets, potentially through interactions with transcriptional activator or repressor complexes.


The actual alignment was detected with superfamily member pfam13871:

Pssm-ID: 464009  Cd Length: 269  Bit Score: 120.74  E-value: 9.76e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 119618810  209 NTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDK 270
Cdd:pfam13871   1 NALDQLIDHLGGPENVAEMTGRSGRIVRKDDGRVVYESRSESDVPLESANLAEKQAFMDGEK 62
AAA_34 super family cl37873
P-loop containing NTP hydrolase pore-1;
2-49 6.72e-22

P-loop containing NTP hydrolase pore-1;


The actual alignment was detected with superfamily member pfam13872:

Pssm-ID: 464010  Cd Length: 300  Bit Score: 92.23  E-value: 6.72e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 119618810    2 GGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNK 49
Cdd:pfam13872 253 RGVGAMELVAMDLKARGLYVARQLSFEGVEFEILEHELSPEQIRVYDA 300
 
Name Accession Description Interval E-value
Helicase_C_4 pfam13871
C-terminal domain on Strawberry notch homolog; Strawberry notch proteins carry DExD/H-box ...
 209-270 9.76e-33

C-terminal domain on Strawberry notch homolog; Strawberry notch proteins carry DExD/H-box groups upstream of this domain. The function of this domain is not known. These proteins promote the expression of diverse targets, potentially through interactions with transcriptional activator or repressor complexes.


Pssm-ID: 464009  Cd Length: 269  Bit Score: 120.74  E-value: 9.76e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 119618810  209 NTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDK 270
Cdd:pfam13871   1 NALDQLIDHLGGPENVAEMTGRSGRIVRKDDGRVVYESRSESDVPLESANLAEKQAFMDGEK 62
AAA_34 pfam13872
P-loop containing NTP hydrolase pore-1;
2-49 6.72e-22

P-loop containing NTP hydrolase pore-1;


Pssm-ID: 464010  Cd Length: 300  Bit Score: 92.23  E-value: 6.72e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 119618810    2 GGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNK 49
Cdd:pfam13872 253 RGVGAMELVAMDLKARGLYVARQLSFEGVEFEILEHELSPEQIRVYDA 300
 
Name Accession Description Interval E-value
Helicase_C_4 pfam13871
C-terminal domain on Strawberry notch homolog; Strawberry notch proteins carry DExD/H-box ...
 209-270 9.76e-33

C-terminal domain on Strawberry notch homolog; Strawberry notch proteins carry DExD/H-box groups upstream of this domain. The function of this domain is not known. These proteins promote the expression of diverse targets, potentially through interactions with transcriptional activator or repressor complexes.


Pssm-ID: 464009  Cd Length: 269  Bit Score: 120.74  E-value: 9.76e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 119618810  209 NTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDK 270
Cdd:pfam13871   1 NALDQLIDHLGGPENVAEMTGRSGRIVRKDDGRVVYESRSESDVPLESANLAEKQAFMDGEK 62
AAA_34 pfam13872
P-loop containing NTP hydrolase pore-1;
2-49 6.72e-22

P-loop containing NTP hydrolase pore-1;


Pssm-ID: 464010  Cd Length: 300  Bit Score: 92.23  E-value: 6.72e-22
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 119618810    2 GGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNK 49
Cdd:pfam13872 253 RGVGAMELVAMDLKARGLYVARQLSFEGVEFEILEHELSPEQIRVYDA 300
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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