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Conserved domains on  [gi|119592270|gb|EAW71864|]
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Spi-B transcription factor (Spi-1/PU.1 related), isoform CRA_e [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ets super family cl02599
Ets-domain;
1-73 6.46e-24

Ets-domain;


The actual alignment was detected with superfamily member smart00413:

Pssm-ID: 470627  Cd Length: 87  Bit Score: 85.78  E-value: 6.46e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119592270    1 MRECVWWVEPGAGVFQFSSKHKelLARRWGQQKgNRKRMTYQKLARALRNYAKTGEIRKV-KRKLTYQFDSALL 73
Cdd:smart00413 17 NSDIIKWTDRDEGEFKLVDPEE--VARLWGQRK-NKPNMNYEKLSRALRYYYKKNILEKVpGKRLVYKFVKNPL 87
 
Name Accession Description Interval E-value
ETS smart00413
erythroblast transformation specific domain; variation of the helix-turn-helix motif
 1-73 6.46e-24

erythroblast transformation specific domain; variation of the helix-turn-helix motif


Pssm-ID: 197710  Cd Length: 87  Bit Score: 85.78  E-value: 6.46e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119592270    1 MRECVWWVEPGAGVFQFSSKHKelLARRWGQQKgNRKRMTYQKLARALRNYAKTGEIRKV-KRKLTYQFDSALL 73
Cdd:smart00413 17 NSDIIKWTDRDEGEFKLVDPEE--VARLWGQRK-NKPNMNYEKLSRALRYYYKKNILEKVpGKRLVYKFVKNPL 87
Ets pfam00178
Ets-domain;
1-68 6.42e-23

Ets-domain;


Pssm-ID: 459700  Cd Length: 80  Bit Score: 82.93  E-value: 6.42e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119592270   1 MRECVWWVEPGAGVFQFSSKHKelLARRWGQQKGNRKrMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 68
Cdd:pfam00178 15 YSDIIKWTDKEEGEFRLVDPEA--VARLWGKRKGNPK-MTYEKLSRALRYYYKKGILEKVPgKRLTYRF 80
 
Name Accession Description Interval E-value
ETS smart00413
erythroblast transformation specific domain; variation of the helix-turn-helix motif
 1-73 6.46e-24

erythroblast transformation specific domain; variation of the helix-turn-helix motif


Pssm-ID: 197710  Cd Length: 87  Bit Score: 85.78  E-value: 6.46e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119592270    1 MRECVWWVEPGAGVFQFSSKHKelLARRWGQQKgNRKRMTYQKLARALRNYAKTGEIRKV-KRKLTYQFDSALL 73
Cdd:smart00413 17 NSDIIKWTDRDEGEFKLVDPEE--VARLWGQRK-NKPNMNYEKLSRALRYYYKKNILEKVpGKRLVYKFVKNPL 87
Ets pfam00178
Ets-domain;
1-68 6.42e-23

Ets-domain;


Pssm-ID: 459700  Cd Length: 80  Bit Score: 82.93  E-value: 6.42e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119592270   1 MRECVWWVEPGAGVFQFSSKHKelLARRWGQQKGNRKrMTYQKLARALRNYAKTGEIRKVK-RKLTYQF 68
Cdd:pfam00178 15 YSDIIKWTDKEEGEFRLVDPEA--VARLWGKRKGNPK-MTYEKLSRALRYYYKKGILEKVPgKRLTYRF 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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