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Conserved domains on  [gi|119592264|gb|EAW71858|]
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Spi-B transcription factor (Spi-1/PU.1 related), isoform CRA_a [Homo sapiens]

Protein Classification

ETS domain-containing protein( domain architecture ID 10648030)

ETS (erythroblast transformation specific) domain-containing protein may function as a transcriptional regulator

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ETS smart00413
erythroblast transformation specific domain; variation of the helix-turn-helix motif
77-165 6.07e-34

erythroblast transformation specific domain; variation of the helix-turn-helix motif


:

Pssm-ID: 197710  Cd Length: 87  Bit Score: 115.06  E-value: 6.07e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119592264    77 KLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKelLARRWGQQKgNRKRMTYQKLARALRNYAKTGEIRKV-KRK 155
Cdd:smart00413   1 GIQLWQFLLDLLLDPENSDIIKWTDRDEGEFKLVDPEE--VARLWGQRK-NKPNMNYEKLSRALRYYYKKNILEKVpGKR 77
                           90
                   ....*....|
gi 119592264   156 LTYQFDSALL 165
Cdd:smart00413  78 LVYKFVKNPL 87
 
Name Accession Description Interval E-value
ETS smart00413
erythroblast transformation specific domain; variation of the helix-turn-helix motif
77-165 6.07e-34

erythroblast transformation specific domain; variation of the helix-turn-helix motif


Pssm-ID: 197710  Cd Length: 87  Bit Score: 115.06  E-value: 6.07e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119592264    77 KLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKelLARRWGQQKgNRKRMTYQKLARALRNYAKTGEIRKV-KRK 155
Cdd:smart00413   1 GIQLWQFLLDLLLDPENSDIIKWTDRDEGEFKLVDPEE--VARLWGQRK-NKPNMNYEKLSRALRYYYKKNILEKVpGKR 77
                           90
                   ....*....|
gi 119592264   156 LTYQFDSALL 165
Cdd:smart00413  78 LVYKFVKNPL 87
Ets pfam00178
Ets-domain;
79-160 3.38e-33

Ets-domain;


Pssm-ID: 459700  Cd Length: 80  Bit Score: 112.59  E-value: 3.38e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119592264   79 RLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKelLARRWGQQKGNRKrMTYQKLARALRNYAKTGEIRKVK-RKLT 157
Cdd:pfam00178   1 QLWQFLLDLLTDPEYSDIIKWTDKEEGEFRLVDPEA--VARLWGKRKGNPK-MTYEKLSRALRYYYKKGILEKVPgKRLT 77

                  ...
gi 119592264  158 YQF 160
Cdd:pfam00178  78 YRF 80
 
Name Accession Description Interval E-value
ETS smart00413
erythroblast transformation specific domain; variation of the helix-turn-helix motif
77-165 6.07e-34

erythroblast transformation specific domain; variation of the helix-turn-helix motif


Pssm-ID: 197710  Cd Length: 87  Bit Score: 115.06  E-value: 6.07e-34
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119592264    77 KLRLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKelLARRWGQQKgNRKRMTYQKLARALRNYAKTGEIRKV-KRK 155
Cdd:smart00413   1 GIQLWQFLLDLLLDPENSDIIKWTDRDEGEFKLVDPEE--VARLWGQRK-NKPNMNYEKLSRALRYYYKKNILEKVpGKR 77
                           90
                   ....*....|
gi 119592264   156 LTYQFDSALL 165
Cdd:smart00413  78 LVYKFVKNPL 87
Ets pfam00178
Ets-domain;
79-160 3.38e-33

Ets-domain;


Pssm-ID: 459700  Cd Length: 80  Bit Score: 112.59  E-value: 3.38e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119592264   79 RLYQFLLGLLTRGDMRECVWWVEPGAGVFQFSSKHKelLARRWGQQKGNRKrMTYQKLARALRNYAKTGEIRKVK-RKLT 157
Cdd:pfam00178   1 QLWQFLLDLLTDPEYSDIIKWTDKEEGEFRLVDPEA--VARLWGKRKGNPK-MTYEKLSRALRYYYKKGILEKVPgKRLT 77

                  ...
gi 119592264  158 YQF 160
Cdd:pfam00178  78 YRF 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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