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Conserved domains on  [gi|119575681|gb|EAW55277|]
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transmembrane protein 14B, isoform CRA_b [Homo sapiens]

Protein Classification

TMEM14 family protein( domain architecture ID 10508392)

TMEM14 family protein contains four hydrophobic alpha-helical regions, three of which are membrane-spanning, similar to Arabidopsis thaliana fatty acid export proteins

CATH:  1.10.10.1740
Gene Ontology:  GO:0016020

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tmemb_14 pfam03647
Transmembrane proteins 14C; This family of short membrane proteins are as yet uncharacterized.
 24-92 9.51e-14

Transmembrane proteins 14C; This family of short membrane proteins are as yet uncharacterized.


:

Pssm-ID: 461004  Cd Length: 89  Bit Score: 60.98  E-value: 9.51e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119575681   24 SVPSLAAGLLFGSLAGLGAYQLYQDPRNVWGFLaATSVTFVGVMGMRSYYYGKFMPVGLIAGASLLMAA 92
Cdd:pfam03647  22 SVPSLIAGLGFGALLLLGGYLSLNAPYGLELAL-GASAVLAGVMGPRFIKTRKFMPAGLLALLSLLMLA 89
 
Name Accession Description Interval E-value
Tmemb_14 pfam03647
Transmembrane proteins 14C; This family of short membrane proteins are as yet uncharacterized.
 24-92 9.51e-14

Transmembrane proteins 14C; This family of short membrane proteins are as yet uncharacterized.


Pssm-ID: 461004  Cd Length: 89  Bit Score: 60.98  E-value: 9.51e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119575681   24 SVPSLAAGLLFGSLAGLGAYQLYQDPRNVWGFLaATSVTFVGVMGMRSYYYGKFMPVGLIAGASLLMAA 92
Cdd:pfam03647  22 SVPSLIAGLGFGALLLLGGYLSLNAPYGLELAL-GASAVLAGVMGPRFIKTRKFMPAGLLALLSLLMLA 89
 
Name Accession Description Interval E-value
Tmemb_14 pfam03647
Transmembrane proteins 14C; This family of short membrane proteins are as yet uncharacterized.
 24-92 9.51e-14

Transmembrane proteins 14C; This family of short membrane proteins are as yet uncharacterized.


Pssm-ID: 461004  Cd Length: 89  Bit Score: 60.98  E-value: 9.51e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119575681   24 SVPSLAAGLLFGSLAGLGAYQLYQDPRNVWGFLaATSVTFVGVMGMRSYYYGKFMPVGLIAGASLLMAA 92
Cdd:pfam03647  22 SVPSLIAGLGFGALLLLGGYLSLNAPYGLELAL-GASAVLAGVMGPRFIKTRKFMPAGLLALLSLLMLA 89
Aim19 pfam10315
Altered inheritance of mitochondria protein 19; This is a family of conserved proteins found ...
 26-99 3.57e-03

Altered inheritance of mitochondria protein 19; This is a family of conserved proteins found in fungi. The function is not known.


Pssm-ID: 402092  Cd Length: 111  Bit Score: 34.24  E-value: 3.57e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 119575681   26 PSLAAGLLFGSLAGLGAYQLY-QDPRNVWGFLAATSVTFVGVMG---MRSYYYGKFMPVGLiAGASLLMAAKVGVRML 99
Cdd:pfam10315  35 PTRKSCLLFGAAFALGGYMIYdGDLENGSGFTTAWSLLYLLVNGrksIKSLRRGRVWPLAL-SGLALGNAILYGKRFF 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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