|
Name |
Accession |
Description |
Interval |
E-value |
| FAM184 |
pfam15665 |
Family with sequence similarity 184, A and B; The function of FAM184 is not known. |
54-264 |
5.33e-77 |
|
Family with sequence similarity 184, A and B; The function of FAM184 is not known.
Pssm-ID: 464788 [Multi-domain] Cd Length: 211 Bit Score: 252.27 E-value: 5.33e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 54 VIYALNTKNDEHESAIQALKDAHEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLESSLEDHIKMKQQALTEFEAYK 133
Cdd:pfam15665 1 VIYALNTKNDEHEAEIQALKEAHEEEIQQILAETREKILQYKSKIGEELDLKRRIQTLEESLEQHERMKRQALTEFEQYK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 134 HRVEDMQLCAEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLQAAHRREIQELLKSQQDHSASVN 213
Cdd:pfam15665 81 RRVEERELKAEAEHRQRVVELSREVEEAKRAFEEKLESFEQLQAQFEQEKRKALEELRAKHRQEIQELLTTQRAQSASSL 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 119568573 214 KGQEKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKLNKAQSFYERELD 264
Cdd:pfam15665 161 AEQEKLEELHKAELESLRKEVEDLRKEKKKLAEEYEQKLSKAQAFYERELE 211
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
275-1002 |
6.18e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 73.55 E-value: 6.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 275 ESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMAL 354
Cdd:TIGR02168 242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 355 -------LSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSK 427
Cdd:TIGR02168 322 eaqleelESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 428 TQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSK--TLEELAWKHHMAIEAVhSNAIRDK 505
Cdd:TIGR02168 402 IERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEEleRLEEALEELREELEEA-EQALDAA 480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 506 KklqmDLEEQHNKDKLNLEEDKNQLQQELENLKEVLeDKLNTANQEIGHLQDMVrKSEQGLGSA--EGLIASLQDSQERL 583
Cdd:TIGR02168 481 E----RELAQLQARLDSLERLQENLEGFSEGVKALL-KNQSGLSGILGVLSELI-SVDEGYEAAieAALGGRLQAVVVEN 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 584 QNELDLTKDSLKET-------------KDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDL--EIKWTENLRQ- 647
Cdd:TIGR02168 555 LNAAKKAIAFLKQNelgrvtflpldsiKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlgGVLVVDDLDNa 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 648 --ECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQE 725
Cdd:TIGR02168 635 leLAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL 714
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 726 RQRLTQELEELEEQHQQRHKslkeahvLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAhRESMEGFRIEMEQELQT 805
Cdd:TIGR02168 715 EQLRKELEELSRQISALRKD-------LARLEAEVEQLEERIAQLSKELTELEAEIEELEER-LEEAEEELAEAEAEIEE 786
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 806 LRFELEdEGKAMLASLRSELNHQHAAaidllrhnhHQELAAAKMELERSIDISRRQSKEHICRITDLQEELRHREHHISE 885
Cdd:TIGR02168 787 LEAQIE-QLKEELKALREALDELRAE---------LTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 886 LDKEVQHLHENISALTKELEfkgkEILRIRSESNQQIRLHEQDL----NKRLEKELDVMTADH-LREKNIMRADFN---- 956
Cdd:TIGR02168 857 LAAEIEELEELIEELESELE----ALLNERASLEEALALLRSELeelsEELRELESKRSELRReLEELREKLAQLElrle 932
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|.
gi 119568573 957 ----KTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQM-ITELKAMLTE 1002
Cdd:TIGR02168 933 glevRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRrLKRLENKIKE 983
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
230-826 |
1.08e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 72.66 E-value: 1.08e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 230 LNKMLEELRLERKK------LIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIG 303
Cdd:COG1196 198 LERQLEPLERQAEKaeryreLKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 304 KLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLvlka 383
Cdd:COG1196 278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL---- 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 384 shigmlqatqmtqevtiKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEyyERELKN 463
Cdd:COG1196 354 -----------------EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA--EEALLE 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 464 LQSRLEEEVTQLNEAHSKTLEElawkhhmaiEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEvLED 543
Cdd:COG1196 415 RLERLEEELEELEEALAELEEE---------EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE-LLE 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 544 KLNTANQEIGHLQDMVRKSEQGLGSAegLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMK 623
Cdd:COG1196 485 ELAEAAARLLLLLEAEADYEGFLEGV--KAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 624 EE----------EKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDL 693
Cdd:COG1196 563 IEylkaakagraTFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 694 LNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHL 773
Cdd:COG1196 643 AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELE 722
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 119568573 774 QQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEG--KAMLASLRSELN 826
Cdd:COG1196 723 EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEelERELERLEREIE 777
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
87-625 |
2.33e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.51 E-value: 2.33e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 87 TREKILQYKSKVTEELDLRRKIQVLESSLEDHIKMKQQALTEFEAYKHRVEDMQlcaeaqhvQRIVTMSREVEEIRRKFE 166
Cdd:COG1196 220 EELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR--------LELEELELELEEAQAEEY 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 167 EKLRSFGQL--QVQFEKDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELHRmEVESLNKMLEELRLERKKL 244
Cdd:COG1196 292 ELLAELARLeqDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE-ELEEAEAELAEAEEALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 245 IEDYEGKLNKAQSFYERELDTLKRSQLFTA----------------ESLQASKEKEADLRKEFQGQEAILRKTIGKLKTE 308
Cdd:COG1196 371 EAELAEAEEELEELAEELLEALRAAAELAAqleeleeaeeallerlERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 309 LQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGM 388
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLI 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 389 LQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRL 468
Cdd:COG1196 531 GVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLRE 610
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 469 EEEVTQLNEAHSKTLEELAWKHHMAIE-AVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNT 547
Cdd:COG1196 611 ADARYYVLGDTLLGRTLVAARLEAALRrAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE 690
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 119568573 548 ANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEE 625
Cdd:COG1196 691 EELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
163-700 |
2.49e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.51 E-value: 2.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 163 RKFEEKLRsfgQLQVQFEKDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELhRMEVESLNKMLEELRLERK 242
Cdd:COG1196 216 RELKEELK---ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL-RLELEELELELEEAQAEEY 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 243 KL---IEDYEGKLNKAQ---SFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEA 316
Cdd:COG1196 292 ELlaeLARLEQDIARLEerrRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 317 GSLLDKCQKL----------QTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHI 386
Cdd:COG1196 372 AELAEAEEELeelaeelleaLRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 387 GMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQ------------ 454
Cdd:COG1196 452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavavlig 531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 455 --EYYERELKN-LQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQ 531
Cdd:COG1196 532 veAAYEAALEAaLAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 532 QELENL--KEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLnvEGELE 609
Cdd:COG1196 612 DARYYVlgDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL--AERLA 689
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 610 QERQQHEETIAAMKEEEKLKVDKMAHDLEIKwTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKK 689
Cdd:COG1196 690 EEELELEEALLAEEEEERELAEAEEERLEEE-LEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768
|
570
....*....|.
gi 119568573 690 VEDLLNQISLL 700
Cdd:COG1196 769 LERLEREIEAL 779
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
27-614 |
3.54e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.12 E-value: 3.54e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 27 AQLAGHSMDYSQEMHLKMSKKIAQLTKVIYALNTKNDEHESAIQALKDAHEEEIQQI------LAETREKILQYKSKV-- 98
Cdd:COG1196 227 AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELeeaqaeEYELLAELARLEQDIar 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 99 ---------TEELDLRRKIQVLESSLEDHIKMKQQALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSREVEEIRRKFEEKL 169
Cdd:COG1196 307 leerrreleERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 170 RSFGQLQVQFEKDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKLIEDYE 249
Cdd:COG1196 387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 250 GKLNKAQSfYERELDTLKRSQLftAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTA 329
Cdd:COG1196 467 ELLEEAAL-LEAALAELLEELA--EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA 543
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 330 LAIAENNVQVlqKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLK-ASHIGMLQATQMTQEVTIKDLESEKS 408
Cdd:COG1196 544 LAAALQNIVV--EDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARgAIGAAVDLVASDLREADARYYVLGDT 621
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 409 RVNERLSQLEEERAFLRSKTqsLDEEQKQQILELEKkVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAW 488
Cdd:COG1196 622 LLGRTLVAARLEAALRRAVT--LAGRLREVTLEGEG-GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEA 698
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 489 KHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLgs 568
Cdd:COG1196 699 LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI-- 776
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 119568573 569 aEGL-------IASLQDSQERLQnELDLTKDSLKETKDALLNVEGELEQERQQ 614
Cdd:COG1196 777 -EALgpvnllaIEEYEELEERYD-FLSEQREDLEEARETLEEAIEEIDRETRE 827
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
289-617 |
3.64e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.86 E-value: 3.64e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 289 KEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAA 368
Cdd:TIGR02168 687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 369 RERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNE 448
Cdd:TIGR02168 767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 449 AKRTQQEyyereLKNLQSRLEEEVTQLNEAHSKTleelawKHHMAIEAVHSNAIRDKKKLQMDLEEQHNkdklNLEEDKN 528
Cdd:TIGR02168 847 IEELSED-----IESLAAEIEELEELIEELESEL------EALLNERASLEEALALLRSELEELSEELR----ELESKRS 911
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 529 QLQQELENLKEVLED---KLNTANQEIGHLQDMVRKSEQ-GLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNV 604
Cdd:TIGR02168 912 ELRRELEELREKLAQlelRLEGLEVRIDNLQERLSEEYSlTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAA 991
|
330
....*....|...
gi 119568573 605 EGELEQERQQHEE 617
Cdd:TIGR02168 992 IEEYEELKERYDF 1004
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
46-705 |
7.84e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 70.10 E-value: 7.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 46 KKIAQLTKVIYALNTKNDEHESAIQALKDAHEEEIQQILAETREKILQYKSKV----TEELDLRRKIQVLESSLEDHIKM 121
Cdd:TIGR02169 244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIgeleAEIASLERSIAEKERELEDAEER 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 122 KQQALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSR------EVEEIRRKFEEKLRSFGQLQVQFeKDKRLALEDLQA--- 192
Cdd:TIGR02169 324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEyaelkeELEDLRAELEEVDKEFAETRDEL-KDYREKLEKLKRein 402
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 193 AHRREIQELLKSQQ------------------DHSASVNKGQEKAEELHRME--VESLNKMLEELRLERKKLIEDYEgKL 252
Cdd:TIGR02169 403 ELKRELDRLQEELQrlseeladlnaaiagieaKINELEEEKEDKALEIKKQEwkLEQLAADLSKYEQELYDLKEEYD-RV 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 253 NKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLD----------- 321
Cdd:TIGR02169 482 EKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvvveddavak 561
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 322 ------KCQKLQTALAIAENNVQVLQKQL------------------DDAKEGEMALLSKHKEVESELAAARE-----RL 372
Cdd:TIGR02169 562 eaiellKRRKAGRATFLPLNKMRDERRDLsilsedgvigfavdlvefDPKYEPAFKYVFGDTLVVEDIEAARRlmgkyRM 641
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 373 QQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEE--QKQQILELEKKVNEAK 450
Cdd:TIGR02169 642 VTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRldELSQELSDASRKIGEI 721
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 451 RTQQEYYERELKNLQSRLEEEVTQLneahSKTLEELAwkhhmaieavhsNAIRDKKKLQMDLEEqhnkdklnLEEDKNQL 530
Cdd:TIGR02169 722 EKEIEQLEQEEEKLKERLEELEEDL----SSLEQEIE------------NVKSELKELEARIEE--------LEEDLHKL 777
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 531 QQELENLK--------EVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALL 602
Cdd:TIGR02169 778 EEALNDLEarlshsriPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE 857
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 603 NVEGELEQERQQHEETIAAMKEEEK----LKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDRE 678
Cdd:TIGR02169 858 NLNGKKEELEEELEELEAALRDLESrlgdLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIE 937
|
730 740
....*....|....*....|....*..
gi 119568573 679 KNAARDSWQKKVEDLLNQISLLKQNLE 705
Cdd:TIGR02169 938 DPKGEDEEIPEEELSLEDVQAELQRVE 964
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
46-730 |
6.28e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.00 E-value: 6.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 46 KKIAQLTKVIYALNTKNDEHESAIQALkdahEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLESSLEDHIKMKQQA 125
Cdd:TIGR02168 239 EELEELQEELKEAEEELEELTAELQEL----EEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 126 LTEFEAY--------KHRVEDMQLCAEAQHV-----QRIVTMSREVEEIRRKFEEKLRSFGQLQVQFE--KDKRLALEDL 190
Cdd:TIGR02168 315 ERQLEELeaqleeleSKLDELAEELAELEEKleelkEELESLEAELEELEAELEELESRLEELEEQLEtlRSKVAQLELQ 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 191 QAAHRREIQELLKSQQDHSASVNKGQEKAEEL-----------HRMEVESLNKMLEELRLERKKLIEDYEgKLNKAQSFY 259
Cdd:TIGR02168 395 IASLNNEIERLEARLERLEDRRERLQQEIEELlkkleeaelkeLQAELEELEEELEELQEELERLEEALE-ELREELEEA 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 260 ERELDTLKRSqlftAESLQASKEKEADLRKEFQG-QEAIlrKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIA--ENN 336
Cdd:TIGR02168 474 EQALDAAERE----LAQLQARLDSLERLQENLEGfSEGV--KALLKNQSGLSGILGVLSELISVDEGYEAAIEAAlgGRL 547
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 337 VQVLQKQLDDAKEGeMALLSKHK------------------EVESELAAARERLQQQASDLV-----LKASHIGMLQATQ 393
Cdd:TIGR02168 548 QAVVVENLNAAKKA-IAFLKQNElgrvtflpldsikgteiqGNDREILKNIEGFLGVAKDLVkfdpkLRKALSYLLGGVL 626
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 394 MTQEVTIKDLESEKSRVNERLSQLEEER-------AFLRSKTQSLDEEQKQQILELEKKVNEAK-------------RTQ 453
Cdd:TIGR02168 627 VVDDLDNALELAKKLRPGYRIVTLDGDLvrpggviTGGSAKTNSSILERRREIEELEEKIEELEekiaelekalaelRKE 706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 454 QEYYERELKNLQSRLEEEVTQLNEAHSK----TLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQ 529
Cdd:TIGR02168 707 LEELEEELEQLRKELEELSRQISALRKDlarlEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 530 LQQELENLKEvledKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELE 609
Cdd:TIGR02168 787 LEAQIEQLKE----ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 610 QERQQHEETIAAMKEEEKLKVDKMAHdleikwTENLRQECSKLREELRlqHEEDKKSAMSQLLQLKDREKNAARDSWQKK 689
Cdd:TIGR02168 863 ELEELIEELESELEALLNERASLEEA------LALLRSELEELSEELR--ELESKRSELRRELEELREKLAQLELRLEGL 934
|
730 740 750 760
....*....|....*....|....*....|....*....|.
gi 119568573 690 VEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLT 730
Cdd:TIGR02168 935 EVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLK 975
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
79-903 |
1.42e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.85 E-value: 1.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 79 EIQQILAETREKILQYKSKVTEELDLRRKIQVLESSLEDHIKMKQQALTEFEAYKHRVEDmqlcaeaqHVQRIVTMSREV 158
Cdd:TIGR02168 233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYA--------LANEISRLEQQK 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 159 EEIRRKFEEKLRSFGQLQVQFEKDKRlaledlqaaHRREIQELLKSQQDHSASVNKgqekaeelhrmEVESLNKMLEELR 238
Cdd:TIGR02168 305 QILRERLANLERQLEELEAQLEELES---------KLDELAEELAELEEKLEELKE-----------ELESLEAELEELE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 239 LERKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKE---ADLRKEFQGQEAILRKTIGKLKTELQMVQDE 315
Cdd:TIGR02168 365 AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLErleDRRERLQQEIEELLKKLEEAELKELQAELEE 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 316 AGSLLDkcqKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAArERLQQQASDLVLKASHIgMLQATQMT 395
Cdd:TIGR02168 445 LEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKAL-LKNQSGLS 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 396 QevtIKDLESEKSRVNERLSQLEEerAFLRSKTQSL---DEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEV 472
Cdd:TIGR02168 520 G---ILGVLSELISVDEGYEAAIE--AALGGRLQAVvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREIL 594
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 473 TQLNEAHS--KTLEELAWKHHMAIEAVHS---------NAIRDKKKL-------------------------QMDLEEQH 516
Cdd:TIGR02168 595 KNIEGFLGvaKDLVKFDPKLRKALSYLLGgvlvvddldNALELAKKLrpgyrivtldgdlvrpggvitggsaKTNSSILE 674
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 517 NKDKL-NLEEDKNQLQQELENLK---EVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKD 592
Cdd:TIGR02168 675 RRREIeELEEKIEELEEKIAELEkalAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 593 SLKETKDALLNVEGELEQERQQHEETiaamkEEEKLKVDKMAHDLEIKWtENLRQECSKLREELRLQHEEdkksAMSQLL 672
Cdd:TIGR02168 755 ELTELEAEIEELEERLEEAEEELAEA-----EAEIEELEAQIEQLKEEL-KALREALDELRAELTLLNEE----AANLRE 824
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 673 QLKDREKNAARdsWQKKVEDLLNQISLLKQNLEiQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAhv 752
Cdd:TIGR02168 825 RLESLERRIAA--TERRLEDLEEQIEELSEDIE-SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEEL-- 899
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 753 lafQTMEEEKEKEQRALENHLQqkhsaELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLAslrselnhqHAAA 832
Cdd:TIGR02168 900 ---SEELRELESKRSELRRELE-----ELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEA---------LENK 962
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119568573 833 IDLLRHNHHQELAAAKMELERSIDISRRQSKEhicrITDLQEELRHREHHISELDKEVQHLHENISALTKE 903
Cdd:TIGR02168 963 IEDDEEEARRRLKRLENKIKELGPVNLAAIEE----YEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
400-1010 |
6.57e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.42 E-value: 6.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 400 IKDLESEksrVNERLSQLEEERAFLRsKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAH 479
Cdd:COG1196 191 LEDILGE---LERQLEPLERQAEKAE-RYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 480 SKtLEELAWKHHMAIEAVHS--NAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEvLEDKLNTANQEIGHLQD 557
Cdd:COG1196 267 AE-LEELRLELEELELELEEaqAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE-LEEELEELEEELEELEE 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 558 MVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDL 637
Cdd:COG1196 345 ELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELE 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 638 EIKwtENLRQEcsklrEELRLQHEEDKKSAMSQLLQLKDREKNAardswQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQ 717
Cdd:COG1196 425 ELE--EALAEL-----EEEEEEEEEALEEAAEEEAELEEEEEAL-----LELLAELLEEAALLEAALAELLEELAEAAAR 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 718 LQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAhresmegfrI 797
Cdd:COG1196 493 LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA---------I 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 798 EMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHICRITDLQEELR 877
Cdd:COG1196 564 EYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLA 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 878 HREHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFN- 956
Cdd:COG1196 644 GRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEe 723
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 119568573 957 --KTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKL 1010
Cdd:COG1196 724 eaLEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
58-586 |
4.41e-09 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 60.90 E-value: 4.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 58 LNTKNDEHESAIQALKDAHEEEIQQILAETREKILQYKSKVTEEldlRRKIQVLESSLEdhiKMKQQALTEFEAYKHRVE 137
Cdd:pfam15921 247 LEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSA---RSQANSIQSQLE---IIQEQARNQNSMYMRQLS 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 138 DM-----QLCAEAQHVQR------------IVTMSREVEEIRRKFEEKLRSFGQLQVQFEKdkrlALEDLqaaHRREIQ- 199
Cdd:pfam15921 321 DLestvsQLRSELREAKRmyedkieelekqLVLANSELTEARTERDQFSQESGNLDDQLQK----LLADL---HKREKEl 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 200 ELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAE---- 275
Cdd:pfam15921 394 SLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQlest 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 276 ----------------SLQASKEKEADLRKEFQGQEAILRKT---IGKLKT-------ELQMVQDEAGSLLD---KCQKL 326
Cdd:pfam15921 474 kemlrkvveeltakkmTLESSERTVSDLTASLQEKERAIEATnaeITKLRSrvdlklqELQHLKNEGDHLRNvqtECEAL 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 327 QTALAIAENNVQVLQKQLddakEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQ----EVTIKD 402
Cdd:pfam15921 554 KLQMAEKDKVIEILRQQI----ENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKirelEARVSD 629
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 403 LESEKSRV----NERL----------SQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEyYERELKNLQSRL 468
Cdd:pfam15921 630 LELEKVKLvnagSERLravkdikqerDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNK-LKMQLKSAQSEL 708
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 469 EEEVTQL-----NEAHSKTLeELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENL---KEV 540
Cdd:pfam15921 709 EQTRNTLksmegSDGHAMKV-AMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVateKNK 787
|
570 580 590 600
....*....|....*....|....*....|....*....|....*.
gi 119568573 541 LEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNE 586
Cdd:pfam15921 788 MAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQE 833
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
63-448 |
5.42e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.84 E-value: 5.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 63 DEHESAIQALKDAhEEEIQQILAETREKILQYKSKVTeelDLRRKIQVLESSLEDHIKMKQQALTEFEAYKHRVEDMQLC 142
Cdd:TIGR02168 680 EELEEKIEELEEK-IAELEKALAELRKELEELEEELE---QLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 143 AEAQHVQRIVTmSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLAledlqAAHRREIQELLKSQQDHSASVNKGQEKAEEL 222
Cdd:TIGR02168 756 LTELEAEIEEL-EERLEEAEEELAEAEAEIEELEAQIEQLKEEL-----KALREALDELRAELTLLNEEAANLRERLESL 829
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 223 HRmEVESLNKMLEELRLERKKLIEDYEgKLNKAQSFYERELDTLKRsqlfTAESLQASKEKEADLRKEFQGQEAILRKTI 302
Cdd:TIGR02168 830 ER-RIAATERRLEDLEEQIEELSEDIE-SLAAEIEELEELIEELES----ELEALLNERASLEEALALLRSELEELSEEL 903
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 303 GKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLddaKEGEMALLSKHKEVESELAAARERLQQQASDLVLK 382
Cdd:TIGR02168 904 RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL---SEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119568573 383 ASHIGMLQATqmtqevTIKDLESEKSRVNERLSQ---LEEERAFLRSKTQSLDEEQKQQILELEKKVNE 448
Cdd:TIGR02168 981 IKELGPVNLA------AIEEYEELKERYDFLTAQkedLTEAKETLEEAIEEIDREARERFKDTFDQVNE 1043
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
45-776 |
1.33e-08 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 59.21 E-value: 1.33e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 45 SKKIAQLTKVIYALNTKNDEHESAIQALKDAHEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLESSLEDHIKMKQQ 124
Cdd:pfam02463 263 EEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEK 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 125 ALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALED-LQAAHRREIQELLK 203
Cdd:pfam02463 343 ELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAqLLLELARQLEDLLK 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 204 SQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKL------IEDYEGKLNKAQSFYERELDTLKRSQLFTAESL 277
Cdd:pfam02463 423 EEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDelelkkSEDLLKETQLVKLQEQLELLLSRQKLEERSQKE 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 278 QASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQD---------------EAGSLLDKCQKLQTALAIAENNVQVLQK 342
Cdd:pfam02463 503 SKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEnykvaistavivevsATADEVEERQKLVRALTELPLGARKLRL 582
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 343 QLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERA 422
Cdd:pfam02463 583 LIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKS 662
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 423 FLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAI 502
Cdd:pfam02463 663 EVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLK 742
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 503 RDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQER 582
Cdd:pfam02463 743 QKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQL 822
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 583 LQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEE 662
Cdd:pfam02463 823 LIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKEL 902
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 663 DKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQI--SLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQH 740
Cdd:pfam02463 903 EEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPeeLLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEE 982
|
730 740 750
....*....|....*....|....*....|....*.
gi 119568573 741 QQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQK 776
Cdd:pfam02463 983 FEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
88-448 |
3.26e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.16 E-value: 3.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 88 REKILQYKSKVTEELDLRRKIQVLESSLEDHIKMKQQALTEFEAYKHRVEDMQlcaeaqhvQRIVTMSREVEEIRRKFEE 167
Cdd:TIGR02169 663 RGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDAS--------RKIGEIEKEIEQLEQEEEK 734
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 168 KLRSFGQLQVQFEKdkrlaLEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELHRM----EVESLNKMLEELRLERKK 243
Cdd:TIGR02169 735 LKERLEELEEDLSS-----LEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARlshsRIPEIQAELSKLEEEVSR 809
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 244 L---IEDYEGKLNKAQSFYE-------------RELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKT 307
Cdd:TIGR02169 810 IearLREIEQKLNRLTLEKEylekeiqelqeqrIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKK 889
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 308 ELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESE---------LAAARERLQQQASD 378
Cdd:TIGR02169 890 ERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpeeelsledVQAELQRVEEEIRA 969
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119568573 379 LvlkaSHIGMLqatqmtqevTIKDLESEKSRVNE---RLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNE 448
Cdd:TIGR02169 970 L----EPVNML---------AIQEYEEVLKRLDElkeKRAKLEEERKAILERIEEYEKKKREVFMEAFEAINE 1029
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
25-631 |
7.51e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.07 E-value: 7.51e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 25 ATAQLAGHSMDYSQEMHLKMSKKIAQLTKVIYALNTKNDEHESAIQALKDAHE-----EEIQQIlAETREKILQYKSKVT 99
Cdd:PTZ00121 1350 AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEdkkkaDELKKA-AAAKKKADEAKKKAE 1428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 100 EEL---DLRRKIQvlESSLEDHIKMKQQALTEFEAYKHRVEDMQlcaEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQ 176
Cdd:PTZ00121 1429 EKKkadEAKKKAE--EAKKADEAKKKAEEAKKAEEAKKKAEEAK---KADEAKKKAEEAKKADEAKKKAEEAKKKADEAK 1503
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 177 vQFEKDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQE---KAEELHRmeVESLNKMLEELRLERKKLIE-DYEGKL 252
Cdd:PTZ00121 1504 -KAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEekkKADELKK--AEELKKAEEKKKAEEAKKAEeDKNMAL 1580
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 253 NKAQSFYERELdtlKRSQLFTAESLQASKEKEADLRKEfqgQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAI 332
Cdd:PTZ00121 1581 RKAEEAKKAEE---ARIEEVMKLYEEEKKMKAEEAKKA---EEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKK 1654
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 333 AENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASdlvlkashigmlQATQMTQevtIKDLESEKSRVNE 412
Cdd:PTZ00121 1655 AEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE------------EAKKAEE---LKKKEAEEKKKAE 1719
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 413 RLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEahsktLEELAWKHHM 492
Cdd:PTZ00121 1720 ELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE-----LDEEDEKRRM 1794
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 493 AIEavhsNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGlGSAEGL 572
Cdd:PTZ00121 1795 EVD----KKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGED-GNKEAD 1869
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*....
gi 119568573 573 IASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVD 631
Cdd:PTZ00121 1870 FNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRD 1928
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
180-1012 |
1.43e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 56.13 E-value: 1.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 180 EKDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKLNKAQSFY 259
Cdd:pfam02463 181 ETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEI 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 260 ERELDTLKRSQLFTAESLQASKEKEaDLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQV 339
Cdd:pfam02463 261 EKEEEKLAQVLKENKEEEKEKKLQE-EELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 340 LQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEE 419
Cdd:pfam02463 340 LEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLED 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 420 ERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEA--- 496
Cdd:pfam02463 420 LLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEers 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 497 VHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEV--------LEDKLNTANQEIGHLQDMVRKSEQGLGS 568
Cdd:pfam02463 500 QKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVaistavivEVSATADEVEERQKLVRALTELPLGARK 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 569 AEGLIASLQDSQERLQ-NELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQ 647
Cdd:pfam02463 580 LRLLIPKLKLPLKSIAvLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLA 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 648 ECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQ 727
Cdd:pfam02463 660 EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELK 739
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 728 RLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRalenhlqqkhsaELQSLKDAHRESMEGFRIEMEQELQTLR 807
Cdd:pfam02463 740 LLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEE------------REKTEKLKVEEEKEEKLKAQEEELRALE 807
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 808 FELEDEGKAMLASLRSELnhQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHICRITDLQEELRHREHHISELD 887
Cdd:pfam02463 808 EELKEEAELLEEEQLLIE--QEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLK 885
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 888 KEVQHLHENISALTKELEFKGKEILRIRSESNqQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINA 967
Cdd:pfam02463 886 DELESKEEKEKEEKKELEEESQKLNLLEEKEN-EIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKR 964
|
810 820 830 840
....*....|....*....|....*....|....*....|....*....
gi 119568573 968 ALQVSLEEMEEKYLMRESKPEDIQ----MITELKAMLTERDQIIKKLIE 1012
Cdd:pfam02463 965 LLLAKEELGKVNLMAIEEFEEKEErynkDELEKERLEEEKKKLIRAIIE 1013
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
337-657 |
1.79e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.84 E-value: 1.79e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 337 VQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLEseksrvnERLSQ 416
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE-------EDLSS 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 417 LEEERAFLRSKTQSLDEEQKQQILELEKkvneakrtqqeyYERELKNLQSRLEEEVTQLNEAHSKTLEElawkHHMAIEA 496
Cdd:TIGR02169 749 LEQEIENVKSELKELEARIEELEEDLHK------------LEEALNDLEARLSHSRIPEIQAELSKLEE----EVSRIEA 812
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 497 VHSNAIRDKKKLQMDLEeqhnkdklnLEEDKnqlQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASL 576
Cdd:TIGR02169 813 RLREIEQKLNRLTLEKE---------YLEKE---IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL 880
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 577 QDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQ---QHEETIAAMKEEEKLKVDKMAHDLEIKWT----ENLRQEC 649
Cdd:TIGR02169 881 ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKrlsELKAKLEALEEELSEIEDPKGEDEEIPEEelslEDVQAEL 960
|
....*...
gi 119568573 650 SKLREELR 657
Cdd:TIGR02169 961 QRVEEEIR 968
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
79-668 |
4.18e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 54.30 E-value: 4.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 79 EIQQILA--ETREKILQ-------YKSKVTEELDLRRKIQVLESSLEDHIKMKQQALTEFEAYKHRVEDMQlcaeaQHVQ 149
Cdd:PRK03918 136 EIDAILEsdESREKVVRqilglddYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVL-----REIN 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 150 RIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLQaaHRREIQELLKSQQDHSASVNKGQEKAEELHRmEVES 229
Cdd:PRK03918 211 EISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEG--SKRKLEEKIRELEERIEELKKEIEELEEKVK-ELKE 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 230 LNKMLEELRlERKKLIEDYEGKLNKAqsfyERELDTLKRSQLFTAESLQASKEKEADLrKEFQGQEAILRKTIGKLKTEL 309
Cdd:PRK03918 288 LKEKAEEYI-KLSEFYEEYLDELREI----EKRLSRLEEEINGIEERIKELEEKEERL-EELKKKLKELEKRLEELEERH 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 310 QMVQdEAGSLLDKCQKLQTALAIaeNNVQVLQKQLDDAKEgemallsKHKEVESELAAARERLQQQASDLVLKASHIGML 389
Cdd:PRK03918 362 ELYE-EAKAKKEELERLKKRLTG--LTPEKLEKELEELEK-------AKEEIEEEISKITARIGELKKEIKELKKAIEEL 431
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 390 QATQMTQEVTIKDLESE-----KSRVNERLSQLEEERAFLRSKTQSLDEEQKqqilELEKKVNEAKR-TQQEYYERELKN 463
Cdd:PRK03918 432 KKAKGKCPVCGRELTEEhrkelLEEYTAELKRIEKELKEIEEKERKLRKELR----ELEKVLKKESElIKLKELAEQLKE 507
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 464 LQSRLE----EEVTQLNEAHSKTLEELAwkhhmAIEAVHSNAIRDKKKLqmdleEQHNKDKLNLEEDKNQLQQELENLKE 539
Cdd:PRK03918 508 LEEKLKkynlEELEKKAEEYEKLKEKLI-----KLKGEIKSLKKELEKL-----EELKKKLAELEKKLDELEEELAELLK 577
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 540 VLEDK----LNTANQEIGHLQDMVRKSEQgLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQH 615
Cdd:PRK03918 578 ELEELgfesVEELEERLKELEPFYNEYLE-LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY 656
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 119568573 616 EETIAAMKEEEKLKVDKMAHDL--EIKWTENLRQECSKLREELRLQHEEDKKSAM 668
Cdd:PRK03918 657 SEEEYEELREEYLELSRELAGLraELEELEKRREEIKKTLEKLKEELEEREKAKK 711
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
111-991 |
1.68e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.84 E-value: 1.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 111 LESSLEDHIKMKQQALTEfEAYKHRVEDMQLCAEAQHVQRIVTMSREVEEIR-----RKFEEKLRSFGQLQVQFEK---D 182
Cdd:PTZ00121 1084 KEDNRADEATEEAFGKAE-EAKKTETGKAEEARKAEEAKKKAEDARKAEEARkaedaRKAEEARKAEDAKRVEIARkaeD 1162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 183 KRLALEDLQAAHRREIQELLKSQQdhsasVNKGQE--KAEELHRmeVESLNKMLEELRLERKKLIEDyegklnkaqsfyE 260
Cdd:PTZ00121 1163 ARKAEEARKAEDAKKAEAARKAEE-----VRKAEElrKAEDARK--AEAARKAEEERKAEEARKAED------------A 1223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 261 RELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTAlaiaennvQVL 340
Cdd:PTZ00121 1224 KKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKA--------DEA 1295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 341 QKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDlESEKSRVNERLSQLEEE 420
Cdd:PTZ00121 1296 KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD-EAEAAEEKAEAAEKKKE 1374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 421 RAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYyerelknlqSRLEEEVTQLNEAHSKTLEelawkhhmaieavhsn 500
Cdd:PTZ00121 1375 EAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADEL---------KKAAAAKKKADEAKKKAEE---------------- 1429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 501 aIRDKKKLQMDLEEQHNKDKLnleEDKNQLQQELENLKEVLEDKLNTanQEIGHLQDMVRKSEQGLGSAEGliASLQDSQ 580
Cdd:PTZ00121 1430 -KKKADEAKKKAEEAKKADEA---KKKAEEAKKAEEAKKKAEEAKKA--DEAKKKAEEAKKADEAKKKAEE--AKKKADE 1501
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 581 ERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEEtiaAMKEEEKLKVDkmahdlEIKWTENLRQECSKLREELRLQH 660
Cdd:PTZ00121 1502 AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADE---AKKAEEKKKAD------ELKKAEELKKAEEKKKAEEAKKA 1572
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 661 EEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQH 740
Cdd:PTZ00121 1573 EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL 1652
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 741 QQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL---QTLRFElEDEGKAM 817
Cdd:PTZ00121 1653 KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKkkaEELKKA-EEENKIK 1731
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 818 LASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHIcritdLQEELRHR-EHHISELDKEVQHLHEN 896
Cdd:PTZ00121 1732 AEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV-----IEEELDEEdEKRRMEVDKKIKDIFDN 1806
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 897 iSALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNIMRADFNKTNELLKEINaALQVSLEEM 976
Cdd:PTZ00121 1807 -FANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKD-LKEDDEEEI 1884
|
890
....*....|....*
gi 119568573 977 EEKYLMRESKPEDIQ 991
Cdd:PTZ00121 1885 EEADEIEKIDKDDIE 1899
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
235-935 |
8.13e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 50.35 E-value: 8.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 235 EELRLERKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKT--ELQMV 312
Cdd:TIGR00618 179 TQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAqeEQLKK 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 313 QDEAGSLLDKCQKLQTALAIAENnvqvLQKQLDDAKEGE-MALLSKH-KEVESELAAARERLQQQASDLVLKASHIGMLQ 390
Cdd:TIGR00618 259 QQLLKQLRARIEELRAQEAVLEE----TQERINRARKAApLAAHIKAvTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHV 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 391 ATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQ-----KQQILELEKKVNEAKRTQQEYYERELKNLQ 465
Cdd:TIGR00618 335 KQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQhihtlQQQKTTLTQKLQSLCKELDILQREQATIDT 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 466 SRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEE--QHNKDKLNLEEDKNQLQQELENLKEVLED 543
Cdd:TIGR00618 415 RTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQEsaQSLKEREQQLQTKEQIHLQETRKKAVVLA 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 544 KLntanQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMK 623
Cdd:TIGR00618 495 RL----LELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQ 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 624 EEEKLKVDKMAHDLEIkwtENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAArdswqkkvedlLNQISLLKQN 703
Cdd:TIGR00618 571 SFSILTQCDNRSKEDI---PNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQD-----------LQDVRLHLQQ 636
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 704 LEIQLSQSQTSLQQLQAQFTQERQRLtqeleeleeqhqqrhkslkeaHVLAFQTMEEEKEKEQRALENHLQQKhsaelqs 783
Cdd:TIGR00618 637 CSQELALKLTALHALQLTLTQERVRE---------------------HALSIRVLPKELLASRQLALQKMQSE------- 688
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 784 lkdahRESMEGFRIEMEQELQTLRFELEDEGKamlaslrselNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSK 863
Cdd:TIGR00618 689 -----KEQLTYWKEMLAQCQTLLRELETHIEE----------YDREFNEIENASSSLGSDLAAREDALNQSLKELMHQAR 753
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 119568573 864 EHICRITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRLEK 935
Cdd:TIGR00618 754 TVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCET 825
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
180-656 |
8.89e-06 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 50.04 E-value: 8.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 180 EKDKRLALEDLQAahrrEIQEllKSQQDHSASVNKGQEKAEELhRMEVESLNKMLE---ELRLERKKLIEDYEGKLnkaq 256
Cdd:PRK02224 182 LSDQRGSLDQLKA----QIEE--KEEKDLHERLNGLESELAEL-DEEIERYEEQREqarETRDEADEVLEEHEERR---- 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 257 sfyeRELDTLKRsqlfTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAG------------------- 317
Cdd:PRK02224 251 ----EELETLEA----EIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGlddadaeavearreeledr 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 318 --SLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMT 395
Cdd:PRK02224 323 deELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGD 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 396 QEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDE--EQKQQILELEK--------------KVNEAKRTQQEYYER 459
Cdd:PRK02224 403 APVDLGNAEDFLEELREERDELREREAELEATLRTARErvEEAEALLEAGKcpecgqpvegsphvETIEEDRERVEELEA 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 460 ELKNL---QSRLEEEVTQLNEAHS------------KTLEELAWKHHMAIEAvHSNAIRDKKKLQMDLEEQHNKDKLNLE 524
Cdd:PRK02224 483 ELEDLeeeVEEVEERLERAEDLVEaedrierleerrEDLEELIAERRETIEE-KRERAEELRERAAELEAEAEEKREAAA 561
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 525 EDKNQLQQELENLKEvLEDKLNTANQEIGHLQDmVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNV 604
Cdd:PRK02224 562 EAEEEAEEAREEVAE-LNSKLAELKERIESLER-IRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKREL 639
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 119568573 605 EGELE--------QERQQHEETIAAMKEE-EKLKVDKMAHDLEIKWTENLRQECSKLREEL 656
Cdd:PRK02224 640 EAEFDearieearEDKERAEEYLEQVEEKlDELREERDDLQAEIGAVENELEELEELRERR 700
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
181-615 |
1.18e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.38 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 181 KDKRLALEDLQAAhRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKLNKAQ---S 257
Cdd:COG4717 64 RKPELNLKELKEL-EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEaelA 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 258 FYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNV 337
Cdd:COG4717 143 ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 338 QVLQKQLDDAkEGEMALLSKHKEVESE-----LAAARERLQQQASDLVLKASHIG----------MLQATQMTQEVTIKD 402
Cdd:COG4717 223 EELEEELEQL-ENELEAAALEERLKEArllllIAAALLALLGLGGSLLSLILTIAgvlflvlgllALLFLLLAREKASLG 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 403 LESEKSRVNERLSQLEEER-AFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQL-NEAHS 480
Cdd:COG4717 302 KEAEELQALPALEELEEEElEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALlAEAGV 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 481 KTLEELAWKHHMAIEAVhsNAIRDKKKLQMDLEEQHNKDKLNLE-EDKNQLQQELENLK---EVLEDKLNTANQEIGHLQ 556
Cdd:COG4717 382 EDEEELRAALEQAEEYQ--ELKEELEELEEQLEELLGELEELLEaLDEEELEEELEELEeelEELEEELEELREELAELE 459
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 119568573 557 DMVRKSEQglgsaEGLIASLQDSQERLQNEL-DLTKD--SLKETKDALLNVEGELEQERQQH 615
Cdd:COG4717 460 AELEQLEE-----DGELAELLQELEELKAELrELAEEwaALKLALELLEEAREEYREERLPP 516
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
509-705 |
1.62e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.61 E-value: 1.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 509 QMDLEEQHNKDKLNLEEDKNQLQQELENLK---EVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQN 585
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKkeeKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 586 ELDLTKDSLKETKDA------------LLNVE------------GELEQERQQHEETIAAMKEEekLKVDKMAHDLEIKW 641
Cdd:COG4942 98 ELEAQKEELAELLRAlyrlgrqpplalLLSPEdfldavrrlqylKYLAPARREQAEELRADLAE--LAALRAELEAERAE 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 119568573 642 TENLRQEcsKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLE 705
Cdd:COG4942 176 LEALLAE--LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
71-630 |
1.82e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 49.20 E-value: 1.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 71 ALKDAHEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLESSLEDHIKMKQQALTEFE-------AYKHRVEDMQLCA 143
Cdd:TIGR00618 333 HVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTqklqslcKELDILQREQATI 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 144 EAQHVQRIV-----TMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLQAAHRREIQELLKSQQDHsasvnkgqEK 218
Cdd:TIGR00618 413 DTRTSAFRDlqgqlAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIH--------LQ 484
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 219 AEELHRMEVESLNKMLEELRLERKKLIEDYEgklnKAQSFYERELDTLKRSQLFtaESLQASKEKEADLRKEFQGqeaiL 298
Cdd:TIGR00618 485 ETRKKAVVLARLLELQEEPCPLCGSCIHPNP----ARQDIDNPGPLTRRMQRGE--QTYAQLETSEEDVYHQLTS----E 554
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 299 RKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGE--MALLSKHKEVESELAAARERL---- 372
Cdd:TIGR00618 555 RKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEdmLACEQHALLRKLQPEQDLQDVrlhl 634
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 373 QQQASDLVLKASHIGMLQATQMTQEVTIKDL---ESEKSRVNERLSQLEEERAFLRSKTQSLDE-EQKQQILELEKKVNE 448
Cdd:TIGR00618 635 QQCSQELALKLTALHALQLTLTQERVREHALsirVLPKELLASRQLALQKMQSEKEQLTYWKEMlAQCQTLLRELETHIE 714
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 449 AKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHnkdklnLEEDKN 528
Cdd:TIGR00618 715 EYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSH------LAAEIQ 788
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 529 QLQQELENLKEVLEDKLNTANQEIGHlqdmvrkseqGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGEL 608
Cdd:TIGR00618 789 FFNRLREEDTHLLKTLEAEIGQEIPS----------DEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECS 858
|
570 580
....*....|....*....|..
gi 119568573 609 EQERQQHEETIAAMKEEEKLKV 630
Cdd:TIGR00618 859 KQLAQLTQEQAKIIQLSDKLNG 880
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
231-1010 |
2.00e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.91 E-value: 2.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 231 NKMLEELRLERKKLIED------YEGKLNKAQSFYERELDTLKRSQLFTAESLQASK--EKEADLRKEFQGQEAILRKTI 302
Cdd:TIGR02169 145 TDFISMSPVERRKIIDEiagvaeFDRKKEKALEELEEVEENIERLDLIIDEKRQQLErlRREREKAERYQALLKEKREYE 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 303 GKLktelqmvqdeagsLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLK 382
Cdd:TIGR02169 225 GYE-------------LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLR 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 383 -ASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYErel 461
Cdd:TIGR02169 292 vKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELED--- 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 462 knLQSRLEEEVTQLNEAHSKT------LEELAWKHHmAIEAVHSNAIRDKKKLQMDLEEQHNKDKlNLEEDKNQLQQEle 535
Cdd:TIGR02169 369 --LRAELEEVDKEFAETRDELkdyrekLEKLKREIN-ELKRELDRLQEELQRLSEELADLNAAIA-GIEAKINELEEE-- 442
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 536 nlKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDL---TKDSLKETKDALLNVEGELEQER 612
Cdd:TIGR02169 443 --KEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEaeaQARASEERVRGGRAVEEVLKASI 520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 613 QQHEETIAAM---KEEEKLKVDKMAH---DLEIKWTENLRQEC-----------------SKLREELRLQHEEDKKSAMS 669
Cdd:TIGR02169 521 QGVHGTVAQLgsvGERYATAIEVAAGnrlNNVVVEDDAVAKEAiellkrrkagratflplNKMRDERRDLSILSEDGVIG 600
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 670 QLLQLKDREKNAARDSWQ-----------KKVEDLLNQISLLKQNLEIQL--------SQSQTSLQQLQAQFTQERQRLT 730
Cdd:TIGR02169 601 FAVDLVEFDPKYEPAFKYvfgdtlvvediEAARRLMGKYRMVTLEGELFEksgamtggSRAPRGGILFSRSEPAELQRLR 680
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 731 QELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALE-----NHLQQKHSAELQSLKDAHR--ESMEGFRIEMEQEL 803
Cdd:TIGR02169 681 ERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEiekeiEQLEQEEEKLKERLEELEEdlSSLEQEIENVKSEL 760
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 804 QTLRFELEDEgKAMLASLRSELNhqhaaaiDLLRHNHHQELAAAKMELERSIDISRRQSKehicRITDLQEELRHREHHI 883
Cdd:TIGR02169 761 KELEARIEEL-EEDLHKLEEALN-------DLEARLSHSRIPEIQAELSKLEEEVSRIEA----RLREIEQKLNRLTLEK 828
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 884 SELDKEVQHLHENISALTKELEFKGKEI--LRIRSESNQQ----IRLHEQDLNKR---LEKELDVMTAdHLRE----KNI 950
Cdd:TIGR02169 829 EYLEKEIQELQEQRIDLKEQIKSIEKEIenLNGKKEELEEeleeLEAALRDLESRlgdLKKERDELEA-QLRElerkIEE 907
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119568573 951 MRADFNKTNELLKEINAALQVSLEEM---EEKYLMRESKPEDIQMITELKAMLTERDQIIKKL 1010
Cdd:TIGR02169 908 LEAQIEKKRKRLSELKAKLEALEEELseiEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
43-561 |
4.53e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 47.71 E-value: 4.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 43 KMSKKIAQLTKVIYALNTKNDEHESAIQ----ALKDAHEEE--IQQILAETREKILQYKSKVTEELDLRRKiqvlESSLE 116
Cdd:TIGR04523 156 KLNNKYNDLKKQKEELENELNLLEKEKLniqkNIDKIKNKLlkLELLLSNLKKKIQKNKSLESQISELKKQ----NNQLK 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 117 DHIKMKQQALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSR---EVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLQAA 193
Cdd:TIGR04523 232 DNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEkqkELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKE 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 194 HRREIQELLKSQQDHSASVNKGQEKAEELHRmEVESLNKMLEELRLERKKLIEDYEGKlnkaqsfyERELDTLKRSQLFT 273
Cdd:TIGR04523 312 LKSELKNQEKKLEEIQNQISQNNKIISQLNE-QISQLKKELTNSESENSEKQRELEEK--------QNEIEKLKKENQSY 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 274 AESLQASKEKEADLRKEFQGQE---AILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEG 350
Cdd:TIGR04523 383 KQEIKNLESQINDLESKIQNQEklnQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNT 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 351 EMALLSKHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQS 430
Cdd:TIGR04523 463 RESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISD 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 431 LDEEQ------------KQQILELEKKVNEAKRTQQeyyerELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAvh 498
Cdd:TIGR04523 543 LEDELnkddfelkkenlEKEIDEKNKEIEELKQTQK-----SLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSL-- 615
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119568573 499 SNAIRDKKKLQMDLEEQhnkdKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRK 561
Cdd:TIGR04523 616 EKELEKAKKENEKLSSI----IKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTK 674
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
197-948 |
4.59e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.81 E-value: 4.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 197 EIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKLIeDYEGKLNKAQSFYERELDT----LKRSQLF 272
Cdd:pfam15921 82 EYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMA-DIRRRESQSQEDLRNQLQNtvheLEAAKCL 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 273 TAESLQASKEKEADLRKEFQGQEAILRktigKLKTELQMVQDEAGSLLDKCQKLQTALaiAENNVQVLQKQLDDAKEGEM 352
Cdd:pfam15921 161 KEDMLEDSNTQIEQLRKMMLSHEGVLQ----EIRSILVDFEEASGKKIYEHDSMSTMH--FRSLGSAISKILRELDTEIS 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 353 ALLSKHKEVESELAAARERLQQQASdlVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLD 432
Cdd:pfam15921 235 YLKGRIFPVEDQLEALKSESQNKIE--LLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQN 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 433 EEQKQQILELEKKVNEAK---RTQQEYYERELKNLQSRLEEEVTQLNEAHSKtleelawKHHMAIEAvhSNAIRDKKKLQ 509
Cdd:pfam15921 313 SMYMRQLSDLESTVSQLRselREAKRMYEDKIEELEKQLVLANSELTEARTE-------RDQFSQES--GNLDDQLQKLL 383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 510 MDLEEQHNKDKLNLEEDKNQLQQELENLKEV--LEDKLNTANQEIGHLQDMVRK-SEQGLGSAEGLIASLQDSQERLQN- 585
Cdd:pfam15921 384 ADLHKREKELSLEKEQNKRLWDRDTGNSITIdhLRRELDDRNMEVQRLEALLKAmKSECQGQMERQMAAIQGKNESLEKv 463
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 586 -----ELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLkvdkmahdleikwTENLRQECSKLRE--ELRL 658
Cdd:pfam15921 464 ssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERA-------------IEATNAEITKLRSrvDLKL 530
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 659 QHEEDKKSAMSQLlqlkdREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQrltqeleeLEE 738
Cdd:pfam15921 531 QELQHLKNEGDHL-----RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQ--------LEK 597
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 739 QHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQ-----KHSAELQSLKDAHREsmegfRIEMEQELQTLRFELEDE 813
Cdd:pfam15921 598 EINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKvklvnAGSERLRAVKDIKQE-----RDQLLNEVKTSRNELNSL 672
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 814 GKAMLASLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHICRIT-DLQEELRHREHHISELDKEVQH 892
Cdd:pfam15921 673 SEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAmGMQKQITAKRGQIDALQSKIQF 752
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 119568573 893 LHENISALTKELEFKGKEilriRSESNQQIRLHEQDLNKrLEKELDVMTADHLREK 948
Cdd:pfam15921 753 LEEAMTNANKEKHFLKEE----KNKLSQELSTVATEKNK-MAGELEVLRSQERRLK 803
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
105-897 |
4.78e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.76 E-value: 4.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 105 RRKIQVLESSLEDHIKMKQQALTEFEAYKHRVEDMQLCaeaqhvqrIVTMSREVEEIRRKFEEKLRsFGQLQVQFEKDKR 184
Cdd:TIGR02169 155 RRKIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLI--------IDEKRQQLERLRREREKAER-YQALLKEKREYEG 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 185 LALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELhRMEVESLNKMLEELRLERKKLIEDYEGKLNKAQSFYERELD 264
Cdd:TIGR02169 226 YELLKEKEALERQKEAIERQLASLEEELEKLTEEISEL-EKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIA 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 265 TLKRSQLFTAESLQASKEKEADLRKEFQGQEAilrkTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQL 344
Cdd:TIGR02169 305 SLERSIAEKERELEDAEERLAKLEAEIDKLLA----EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 345 DDAKEGEMAL---LSKHKEVESELAAARERLQQQASDLVLKASHIGMlqatqmtqevtikDLESEKSRVNERLSQLEEER 421
Cdd:TIGR02169 381 AETRDELKDYrekLEKLKREINELKRELDRLQEELQRLSEELADLNA-------------AIAGIEAKINELEEEKEDKA 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 422 AFLRSKTQSLdeEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLN-----EAHSKTLEELAWKHHMAIEA 496
Cdd:TIGR02169 448 LEIKKQEWKL--EQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARaseerVRGGRAVEEVLKASIQGVHG 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 497 VHSNAIRDKKKLQMDLE-EQHNKDKLNLEEDKNQLQQELENLKEVledKLNTAN-QEIGHLQDMVRksEQGLGSAEGLIA 574
Cdd:TIGR02169 526 TVAQLGSVGERYATAIEvAAGNRLNNVVVEDDAVAKEAIELLKRR---KAGRATfLPLNKMRDERR--DLSILSEDGVIG 600
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 575 ---SLQDSQERLQNEL------DLTKDSLKETKDALLNV-----EGELEQER------QQHEETIAAMKEEEKLKVDKMA 634
Cdd:TIGR02169 601 favDLVEFDPKYEPAFkyvfgdTLVVEDIEAARRLMGKYrmvtlEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLR 680
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 635 HDLEikwteNLRQECSKLREELRLQheedkKSAMSQLLQLKDREknaardswQKKVEDLLNQISLLKQNLEIQLSQSQTS 714
Cdd:TIGR02169 681 ERLE-----GLKRELSSLQSELRRI-----ENRLDELSQELSDA--------SRKIGEIEKEIEQLEQEEEKLKERLEEL 742
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 715 lqqlqaqftQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHREsMEG 794
Cdd:TIGR02169 743 ---------EEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSR-IEA 812
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 795 FRIEMEQELQ--TLRFELEDEGKAMLASLRSELNHQHAAaidllRHNHHQELAAAKMELERSIDISRRQSKEHICRITDL 872
Cdd:TIGR02169 813 RLREIEQKLNrlTLEKEYLEKEIQELQEQRIDLKEQIKS-----IEKEIENLNGKKEELEEELEELEAALRDLESRLGDL 887
|
810 820
....*....|....*....|....*
gi 119568573 873 QEELRHREHHISELDKEVQHLHENI 897
Cdd:TIGR02169 888 KKERDELEAQLRELERKIEELEAQI 912
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
227-878 |
5.33e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.60 E-value: 5.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 227 VESLNKMLEELRLERKKLIEDYE------GKLNKAqsfyERELDTLKRsQLFTAESLQASKEKEADLRKEFQGQEAIL-- 298
Cdd:COG4913 206 IGDLDDFVREYMLEEPDTFEAADalvehfDDLERA----HEALEDARE-QIELLEPIRELAERYAAARERLAELEYLRaa 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 299 ------RKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSK---HKEVE-SELAAA 368
Cdd:COG4913 281 lrlwfaQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEReieRLERElEERERR 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 369 RERLQQQASDLVLK---------------ASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDE 433
Cdd:COG4913 361 RARLEALLAALGLPlpasaeefaalraeaAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPA 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 434 EQKQQILELEKKVNEAkrtqqeyyERELKNLQsrleeEVTQLNEahsktlEELAWkhHMAIEAV-HS------------- 499
Cdd:COG4913 441 RLLALRDALAEALGLD--------EAELPFVG-----ELIEVRP------EEERW--RGAIERVlGGfaltllvppehya 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 500 ------NAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELEN--------LKEVLEDKLN-----------------TA 548
Cdd:COG4913 500 aalrwvNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFkphpfrawLEAELGRRFDyvcvdspeelrrhpraiTR 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 549 NQEIGHLQDMVRK-------SEQGLG-SAEGLIASLQDSQERLQNELDLTKDSLKEtkdalLNVEGELEQERQQHEETIA 620
Cdd:COG4913 580 AGQVKGNGTRHEKddrrrirSRYVLGfDNRAKLAALEAELAELEEELAEAEERLEA-----LEAELDALQERREALQRLA 654
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 621 AMKEEEklkVDKMAHDLEIkwtENLRQEcsklREELRlqheedkkSAMSQLLQLKDR--EKNAARDSWQKKVEDLLNQIS 698
Cdd:COG4913 655 EYSWDE---IDVASAEREI---AELEAE----LERLD--------ASSDDLAALEEQleELEAELEELEEELDELKGEIG 716
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 699 LLKQNLEiqlsqsqtslqqlqaQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLafQTMEEEKEKEQRALENHLQQKHS 778
Cdd:COG4913 717 RLEKELE---------------QAEEELDELQDRLEAAEDLARLELRALLEERFA--AALGDAVERELRENLEERIDALR 779
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 779 AELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGK--AMLASLRSE-LNHQHAAAIDLLRHNHHQELAAAKMELERSI 855
Cdd:COG4913 780 ARLNRAEEELERAMRAFNREWPAETADLDADLESLPEylALLDRLEEDgLPEYEERFKELLNENSIEFVADLLSKLRRAI 859
|
730 740
....*....|....*....|...
gi 119568573 856 DISRRqskehicRITDLQEELRH 878
Cdd:COG4913 860 REIKE-------RIDPLNDSLKR 875
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
455-905 |
8.52e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 47.04 E-value: 8.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 455 EYYERELKNLQSRLEEEvtqlNEAHSKtlEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKlnlEEDKNQLQ--- 531
Cdd:pfam15921 81 EEYSHQVKDLQRRLNES----NELHEK--QKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQ---EDLRNQLQntv 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 532 QELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELD------------LTKDSLKE--- 596
Cdd:pfam15921 152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDsmstmhfrslgsAISKILREldt 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 597 ----TKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWT------ENLRQECSKLREELRLQHEEDKKS 666
Cdd:pfam15921 232 eisyLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITgltekaSSARSQANSIQSQLEIIQEQARNQ 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 667 AMSQLLQLKDREKNA---------ARDSWQKKVEDLLNQISLLKQNLeiqlsqsqTSLQQLQAQFTQERQRLTQELEELE 737
Cdd:pfam15921 312 NSMYMRQLSDLESTVsqlrselreAKRMYEDKIEELEKQLVLANSEL--------TEARTERDQFSQESGNLDDQLQKLL 383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 738 EQHQQRHKSLkeahvlafqTMEEEKEKE--QRALENHLQQKH--------SAELQSLKDAHRESMEGFRIEMEQELQTLr 807
Cdd:pfam15921 384 ADLHKREKEL---------SLEKEQNKRlwDRDTGNSITIDHlrrelddrNMEVQRLEALLKAMKSECQGQMERQMAAI- 453
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 808 feledEGKAMLASLRSELNHQHAAAIDLLRhNHHQELAAAKMELERSIDIsrrqskehicrITDLQEELRHREHHISELD 887
Cdd:pfam15921 454 -----QGKNESLEKVSSLTAQLESTKEMLR-KVVEELTAKKMTLESSERT-----------VSDLTASLQEKERAIEATN 516
|
490
....*....|....*...
gi 119568573 888 KEVQHLHENISALTKELE 905
Cdd:pfam15921 517 AEITKLRSRVDLKLQELQ 534
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
188-668 |
9.70e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 46.64 E-value: 9.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 188 EDLQAAhRREIQELLKSQQDHSASVNKGQeKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKLNKAQSFYEReldtlK 267
Cdd:pfam05483 317 EDLQIA-TKTICQLTEEKEAQMEELNKAK-AAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQK-----K 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 268 RSQLFTAESLQASKEKEADLRKEFQGQEAIL---RKTIGKLKTELQMVQDEAGSLLDKCQK----LQTALAIAENNVQVL 340
Cdd:pfam05483 390 SSELEEMTKFKNNKEVELEELKKILAEDEKLldeKKQFEKIAEELKGKEQELIFLLQAREKeihdLEIQLTAIKTSEEHY 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 341 QKQLDDAKegemALLSKHKEVESELAAARERLQQQASDLVLKASHIGMlqaTQMTQEVTIKDLESEKSRVNERLSQLEEE 420
Cdd:pfam05483 470 LKEVEDLK----TELEKEKLKNIELTAHCDKLLLENKELTQEASDMTL---ELKKHQEDIINCKKQEERMLKQIENLEEK 542
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 421 RAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKnlqsrlEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSN 500
Cdd:pfam05483 543 EMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLK------KEKQMKILENKCNNLKKQIENKNKNIEELHQE 616
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 501 AIRDKKKLQMDleeqhnKDKLNLEEDK-NQLQQELENLKEVLEDKLNTANQEIghlqdmvrksEQGLGSAEGLIASLQDS 579
Cdd:pfam05483 617 NKALKKKGSAE------NKQLNAYEIKvNKLELELASAKQKFEEIIDNYQKEI----------EDKKISEEKLLEEVEKA 680
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 580 QERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWT-----ENLRQECSKLRE 654
Cdd:pfam05483 681 KAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAAleielSNIKAELLSLKK 760
|
490
....*....|....
gi 119568573 655 ELRLQHEEDKKSAM 668
Cdd:pfam05483 761 QLEIEKEEKEKLKM 774
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
271-477 |
9.88e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 46.83 E-value: 9.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 271 LFTAESLQASKEKEADLRKEFQGQEAILRKT---IGKLKTELQMVQDEAGSLLDKCQkLQTALAIAENNVQVLQKQLDDA 347
Cdd:PRK11281 69 LALLDKIDRQKEETEQLKQQLAQAPAKLRQAqaeLEALKDDNDEETRETLSTLSLRQ-LESRLAQTLDQLQNAQNDLAEY 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 348 KEGEMALLSKHKEVESELAAARERLQQ--------QASDLVLKASHIGMLQATQ-------------MTQEVTIKDL-ES 405
Cdd:PRK11281 148 NSQLVSLQTQPERAQAALYANSQRLQQirnllkggKVGGKALRPSQRVLLQAEQallnaqndlqrksLEGNTQLQDLlQK 227
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 119568573 406 EKSRVNERLSQLEEERAFLR----SKTQSLDEEQKQQILELEKKvneAKRTQQEYYEREL-KNLQ--SRLEEEVTQLNE 477
Cdd:PRK11281 228 QRDYLTARIQRLEHQLQLLQeainSKRLTLSEKTVQEAQSQDEA---ARIQANPLVAQELeINLQlsQRLLKATEKLNT 303
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
210-468 |
1.06e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 1.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 210 ASVNKGQEKAEELHRM--EVESLNKMLEELRLERKKLIEDYEgKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADL 287
Cdd:COG4942 17 AQADAAAEAEAELEQLqqEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 288 RKEFQGQEAILRKTIGKLkteLQMVQDEAGSLLDKCQKLQTALAIAEnnvqvLQKQLDDAKEGEMALLSKHKEvesELAA 367
Cdd:COG4942 96 RAELEAQKEELAELLRAL---YRLGRQPPLALLLSPEDFLDAVRRLQ-----YLKYLAPARREQAEELRADLA---ELAA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 368 ARERLQQQASDLvlkashigmlQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVN 447
Cdd:COG4942 165 LRAELEAERAEL----------EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
|
250 260
....*....|....*....|.
gi 119568573 448 EAKRTQQEYYERELKNLQSRL 468
Cdd:COG4942 235 EAAAAAERTPAAGFAALKGKL 255
|
|
| Nup88 |
pfam10168 |
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ... |
469-654 |
1.14e-04 |
|
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.
Pssm-ID: 462975 [Multi-domain] Cd Length: 713 Bit Score: 46.19 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 469 EEEVTQLNEAHSKTLEELAWKHHMAIEAV--HSNAIRDKKKLQmdLEEQHNkdklnLEEDKNQLQQELENLKEVLEDKLN 546
Cdd:pfam10168 531 QECLQLLSRATQVFREEYLKKHDLAREEIqkRVKLLKLQKEQQ--LQELQS-----LEEERKSLSERAEKLAEKYEEIKD 603
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 547 taNQEighlqDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQheetIAAMKEEE 626
Cdd:pfam10168 604 --KQE-----KLMRRCKKVLQRLNSQLPVLSDAEREMKKELETINEQLKHLANAIKQAKKKMNYQRYQ----IAKSQSIR 672
|
170 180
....*....|....*....|....*...
gi 119568573 627 KLKVDKMAHDLEIKWTENLRQECSKLRE 654
Cdd:pfam10168 673 KKSSLSLSEKQRKTIKEILKQLGSEIDE 700
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
95-616 |
1.24e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 46.43 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 95 KSKVTEELDLRRKIQVLESSLEDHIKMKQQALTEFEAykhrVEDmqlcaEAQHVQRIVTMSREVEEIRRKFEEKLRsfgq 174
Cdd:PRK01156 193 KSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNN----AMD-----DYNNLKSALNELSSLEDMKNRYESEIK---- 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 175 lqvqfEKDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKLiEDYEGKLNK 254
Cdd:PRK01156 260 -----TAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKY-HAIIKKLSV 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 255 AQSFYERELDTLKRsqlftaeslqasKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAE 334
Cdd:PRK01156 334 LQKDYNDYIKKKSR------------YDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQE 401
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 335 NNVQVLQKQLDDAKegemallSKHKEVESELAAARERLQQQASDLVLKASHIGMLQAtQMTQEVTIKDLESEKSR----- 409
Cdd:PRK01156 402 IDPDAIKKELNEIN-------VKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNG-QSVCPVCGTTLGEEKSNhiinh 473
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 410 VNERLSQLEEERAFLRSKTQSLDEEQKQQIlELEKKVNEAKRTQQEYYERELKNLQSRLEE---EVTQLNEAHSKT---- 482
Cdd:PRK01156 474 YNEKKSRLEEKIREIEIEVKDIDEKIVDLK-KRKEYLESEEINKSINEYNKIESARADLEDikiKINELKDKHDKYeeik 552
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 483 -------LEEL-----AWKHHMA------IEAVHSNAIRDKKKLQmDLEEQHNKDKLNLEEDKNQLQQ---ELENLKEVL 541
Cdd:PRK01156 553 nrykslkLEDLdskrtSWLNALAvislidIETNRSRSNEIKKQLN-DLESRLQEIEIGFPDDKSYIDKsirEIENEANNL 631
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 119568573 542 EDKLNTAnQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHE 616
Cdd:PRK01156 632 NNKYNEI-QENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIE 705
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
321-542 |
2.71e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 2.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 321 DKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIgmlQATQMTQEVTI 400
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL---AELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 401 KDLESEKSRVNERL--SQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYER---ELKNLQSRLEEEVTQL 475
Cdd:COG4942 97 AELEAQKEELAELLraLYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAdlaELAALRAELEAERAEL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 119568573 476 NEAHSKTLEELAwkhhmaieavhsnAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLE 542
Cdd:COG4942 177 EALLAELEEERA-------------ALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
356-588 |
2.76e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 2.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 356 SKHKEVESELAAARERLQQQASDLvlkashiGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQ 435
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKEL-------AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 436 KQQILELEKkvneakrtQQEYYERELKNLQsRLEEEVTQLNEAHSKTLEELAwKHHMAIEAVHSNAIRDKKKLQMDLEEQ 515
Cdd:COG4942 93 AELRAELEA--------QKEELAELLRALY-RLGRQPPLALLLSPEDFLDAV-RRLQYLKYLAPARREQAEELRADLAEL 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 119568573 516 HnkdklNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELD 588
Cdd:COG4942 163 A-----ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
399-900 |
4.80e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 44.26 E-value: 4.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 399 TIKDLESEKSRVNERLSQLEEERAFLRSKTQSLD-------------EEQKQQILELEKKVNEAKRTQQEYYEReLKNLQ 465
Cdd:PRK02224 207 RLNGLESELAELDEEIERYEEQREQARETRDEADevleeheerreelETLEAEIEDLRETIAETEREREELAEE-VRDLR 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 466 SRLEEEVTQLNEAHSKT-LEELAWKhhmAIEAVHSNAIRDKKKLQMDLEEQ------HNKDKLNLEEDKNQLQQELENLK 538
Cdd:PRK02224 286 ERLEELEEERDDLLAEAgLDDADAE---AVEARREELEDRDEELRDRLEECrvaaqaHNEEAESLREDADDLEERAEELR 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 539 E---VLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLtkdsLKETKDALLNVEGELEQERQQH 615
Cdd:PRK02224 363 EeaaELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEE----LREERDELREREAELEATLRTA 438
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 616 EETIA---AMKEEEKL-----KVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKsamsQLLQLKDREKNAARdswq 687
Cdd:PRK02224 439 RERVEeaeALLEAGKCpecgqPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEE----RLERAEDLVEAEDR---- 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 688 kkVEDLLNQISLLKQNLEIQLSQSQTSlqqlqaqfTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQR 767
Cdd:PRK02224 511 --IERLEERREDLEELIAERRETIEEK--------RERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 768 ALENhlqqkhSAELQSLKDAhrESMEGFRIEMEQELQTLR------FELEDEGKAMLASLR---SELNHQH-AAAIDLLR 837
Cdd:PRK02224 581 LAEL------KERIESLERI--RTLLAAIADAEDEIERLRekrealAELNDERRERLAEKRerkRELEAEFdEARIEEAR 652
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 119568573 838 HNHHQ-------------ELAAAKMELERSIDISRRQSKEhicritdlQEELRHREHHISELDKEVQHLHENISAL 900
Cdd:PRK02224 653 EDKERaeeyleqveekldELREERDDLQAEIGAVENELEE--------LEELRERREALENRVEALEALYDEAEEL 720
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
38-653 |
4.93e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.44 E-value: 4.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 38 QEMHLKMSKKIAQLTKVIYALNTKNDEHESAIQALKDAHEEEIQQILAETREKIL-QYKSKVTEELDLRRKIQVLESSLE 116
Cdd:pfam12128 346 QEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAkIREARDRQLAVAEDDLQALESELR 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 117 DHIkmkQQALTEFEAYKHRVEDMQLCAEAQHVQRIVTmSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLQAAHRR 196
Cdd:pfam12128 426 EQL---EAGKLEFNEEEYRLKSRLGELKLRLNQATAT-PELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRR 501
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 197 EiqELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLErKKLIEDYEGKLnkaqsfyereldtLKRSQLFtaes 276
Cdd:pfam12128 502 D--QASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKE-APDWEQSIGKV-------------ISPELLH---- 561
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 277 lqaskekEADLRKEFQGQEAILRKTIGKLKTELQMVQdeAGSLLDKCQKLQTALAIAENNVQVlQKQLDDAKEGEMALLS 356
Cdd:pfam12128 562 -------RTDLDPEVWDGSVGGELNLYGVKLDLKRID--VPEWAASEEELRERLDKAEEALQS-AREKQAAAEEQLVQAN 631
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 357 KH-KEVESELAAARERLQQQASDLvlkashIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQ 435
Cdd:pfam12128 632 GElEKASREETFARTALKNARLDL------RRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQ 705
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 436 KQQILELEKKVNEAKRTqqeyYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQ--MDLE 513
Cdd:pfam12128 706 KEQKREARTEKQAYWQV----VEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKReiRTLE 781
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 514 ---EQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELD-- 588
Cdd:pfam12128 782 rkiERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSen 861
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 119568573 589 LTKDSLKETKDALLNVEGELEQERQQHEETIAAMkEEEKLKVDKMAHDLEiKWTENLRQECSKLR 653
Cdd:pfam12128 862 LRGLRCEMSKLATLKEDANSEQAQGSIGERLAQL-EDLKLKRDYLSESVK-KYVEHFKNVIADHS 924
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
187-633 |
7.08e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 43.95 E-value: 7.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 187 LEDLQAAHRREIQELLKSQQDHSasvnkgqEKAEELHRMEVESLNKMLEELRLERKKL---IEDYEGKLNKAQSFYEREL 263
Cdd:pfam15921 247 LEALKSESQNKIELLLQQHQDRI-------EQLISEHEVEITGLTEKASSARSQANSIqsqLEIIQEQARNQNSMYMRQL 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 264 DTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQ 343
Cdd:pfam15921 320 SDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQ 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 344 LDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHIgmlQATQMTQEVTIKDLESEKSRVNERLSQLEEERAF 423
Cdd:pfam15921 400 NKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEC---QGQMERQMAAIQGKNESLEKVSSLTAQLESTKEM 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 424 LRSKTQSLD------EEQKQQILELEKKVNEAKRTqQEYYERELKNLQSRLEEEVTQLNeaHSKTLEELAWKHHMAIEAV 497
Cdd:pfam15921 477 LRKVVEELTakkmtlESSERTVSDLTASLQEKERA-IEATNAEITKLRSRVDLKLQELQ--HLKNEGDHLRNVQTECEAL 553
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 498 HSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELEnlKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQ 577
Cdd:pfam15921 554 KLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVE--KAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE 631
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 578 DSQERLQN----ELDLTKDsLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKM 633
Cdd:pfam15921 632 LEKVKLVNagseRLRAVKD-IKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEM 690
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
208-563 |
8.38e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.57 E-value: 8.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 208 HSASVNKGQEKaEELHRMEVESLNKMLEEL--RLERKKliedyegKLNKAQSFYERELDtlkRSQLFTAESLQASKEKEA 285
Cdd:pfam17380 280 HQKAVSERQQQ-EKFEKMEQERLRQEKEEKarEVERRR-------KLEEAEKARQAEMD---RQAAIYAEQERMAMERER 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 286 DLRKEFQGQEailrktigklKTELQMVQdeagslldkcqklQTALAIAENNVQVLQKQlddakegEMALLSKHKEVESEL 365
Cdd:pfam17380 349 ELERIRQEER----------KRELERIR-------------QEEIAMEISRMRELERL-------QMERQQKNERVRQEL 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 366 AAARE-RLQQQASDLVLKASHIGMLQ---ATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILE 441
Cdd:pfam17380 399 EAARKvKILEEERQRKIQQQKVEMEQiraEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLE 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 442 LEKKvneaKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKtleelawkhhmaieavhsnairdKKKLQMDLEEQHN---- 517
Cdd:pfam17380 479 LEKE----KRDRKRAEEQRRKILEKELEERKQAMIEEERK-----------------------RKLLEKEMEERQKaiye 531
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 119568573 518 KDKLNLEEDKNQLQQELENLKEVlEDKLNTANQEIGHLQDMVRKSE 563
Cdd:pfam17380 532 EERRREAEEERRKQQEMEERRRI-QEQMRKATEERSRLEAMERERE 576
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
362-705 |
9.02e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 43.27 E-value: 9.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 362 ESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLsqlEEERAFLRSKT---QSLDEEQKQQ 438
Cdd:pfam10174 302 ESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRL---EEKESFLNKKTkqlQDLTEEKSTL 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 439 ILELE--KKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHS--KTLEELAWKHHMAIeAVHSNAIRDKKKLQMDLEE 514
Cdd:pfam10174 379 AGEIRdlKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKErvKSLQTDSSNTDTAL-TTLEEALSEKERIIERLKE 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 515 QHNKDKLNLEEDKNQLQQELENLKE---VLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTK 591
Cdd:pfam10174 458 QREREDRERLEELESLKKENKDLKEkvsALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLE 537
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 592 DSLKETKDALLNVEGE---------LEQERQQHEET-------------IAAMKEEEKLKVDKMAHDLEiKWTENLRQEC 649
Cdd:pfam10174 538 NQLKKAHNAEEAVRTNpeindrirlLEQEVARYKEEsgkaqaeverllgILREVENEKNDKDKKIAELE-SLTLRQMKEQ 616
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 119568573 650 SKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLE 705
Cdd:pfam10174 617 NKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQELD 672
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
109-684 |
1.28e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.98 E-value: 1.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 109 QVLE-SSLEDHIKMKQQALTEFEAYKHRVEDMQlcAEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLAL 187
Cdd:COG4913 216 YMLEePDTFEAADALVEHFDDLERAHEALEDAR--EQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 188 EDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKLiedyegklnkaqsfyERELDTLK 267
Cdd:COG4913 294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERL---------------ERELEERE 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 268 RSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQldda 347
Cdd:COG4913 359 RRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR---- 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 348 kegemallskHKEVESELAAARERLQQQ----ASDLVLKASHIgmlqatqmtqEVTIKDLESEKS--RV--NERLSQLEE 419
Cdd:COG4913 435 ----------KSNIPARLLALRDALAEAlgldEAELPFVGELI----------EVRPEEERWRGAieRVlgGFALTLLVP 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 420 ERAF--LRSKTQSLDEEQKQQILELEKKVNEAKRTQQE----YYERELKN--LQSRLEEEVTQLNEAHS-KTLEELAwKH 490
Cdd:COG4913 495 PEHYaaALRWVNRLHLRGRLVYERVRTGLPDPERPRLDpdslAGKLDFKPhpFRAWLEAELGRRFDYVCvDSPEELR-RH 573
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 491 HMAIEA---VHSNAIRDKKKLQMDLEEQH-----NKDKLN-LEEDKNQLQQELENLKEV---LEDKLNTANQEIGHLQ-- 556
Cdd:COG4913 574 PRAITRagqVKGNGTRHEKDDRRRIRSRYvlgfdNRAKLAaLEAELAELEEELAEAEERleaLEAELDALQERREALQrl 653
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 557 DMVRKSEQGLGSAEGLIASLQDSQERLQN------ELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKlKV 630
Cdd:COG4913 654 AEYSWDEIDVASAEREIAELEAELERLDAssddlaALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELD-EL 732
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 119568573 631 DKMAHDLEIKWTENLRQECSKLREELRL-QHEEDKKSAMSQLLQLKDREKNAARD 684
Cdd:COG4913 733 QDRLEAAEDLARLELRALLEERFAAALGdAVERELRENLEERIDALRARLNRAEE 787
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
186-379 |
1.77e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.06 E-value: 1.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 186 ALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELhRMEVESLNKMLEELRLERKKLiedyEGKLNKAQSFYERELDT 265
Cdd:COG4942 38 ELEKELAALKKEEKALLKQLAALERRIAALARRIRAL-EQELAALEAELAELEKEIAEL----RAELEAQKEELAELLRA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 266 LKRSQLFTAESLQASKEKEADLRKEFQGQEAI---LRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAiaenNVQVLQK 342
Cdd:COG4942 113 LYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLapaRREQAEELRADLAELAALRAELEAERAELEALLA----ELEEERA 188
|
170 180 190
....*....|....*....|....*....|....*..
gi 119568573 343 QLDDAKEGEMALLSKHKEVESELAAARERLQQQASDL 379
Cdd:COG4942 189 ALEALKAERQKLLARLEKELAELAAELAELQQEAEEL 225
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
240-458 |
1.85e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.12 E-value: 1.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 240 ERKKLIEDYEGKLNKAQSfyerELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQdEAGSL 319
Cdd:COG3883 27 ELQAELEAAQAELDALQA----ELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY-RSGGS 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 320 LDKCQKLQTALAIAE--NNVQVLQKQLDDAKEgemaLLSKHKEVESELAAARERLQQQASDLVLK----ASHIGMLQATQ 393
Cdd:COG3883 102 VSYLDVLLGSESFSDflDRLSALSKIADADAD----LLEELKADKAELEAKKAELEAKLAELEALkaelEAAKAELEAQQ 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 119568573 394 MTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYE 458
Cdd:COG3883 178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 242
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
195-509 |
2.29e-03 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 42.05 E-value: 2.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 195 RREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLErkkLIEDYEGKLNKAQSFYERELDTLKRSQLFTA 274
Cdd:pfam09731 167 KEASDTAEISREKATDSALQKAEALAEKLKEVINLAKQSEEEAAPP---LLDAAPETPPKLPEHLDNVEEKVEKAQSLAK 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 275 ESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKcqklqtalaiAENNVQVLQKQLDDAKEGEmal 354
Cdd:pfam09731 244 LVDQYKELVASERIVFQQELVSIFPDIIPVLKEDNLLSNDDLNSLIAH----------AHREIDQLSKKLAELKKRE--- 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 355 lskHKEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEvtikdleseksrvnerlsqLEEERAFLRSKTQS-LDE 433
Cdd:pfam09731 311 ---EKHIERALEKQKEELDKLAEELSARLEEVRAADEAQLRLE-------------------FEREREEIRESYEEkLRT 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 434 EQKQQILELEKKVNEAKRTQ-QEYYERELKNLQSRLEEE----VTQLNEAHSKtLEELawkhHMAIEAvHSNAIRDKKKL 508
Cdd:pfam09731 369 ELERQAEAHEEHLKDVLVEQeIELQREFLQDIKEKVEEEragrLLKLNELLAN-LKGL----EKATSS-HSEVEDENRKA 442
|
.
gi 119568573 509 Q 509
Cdd:pfam09731 443 Q 443
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
181-534 |
2.65e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 2.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 181 KDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELHRME--------VESLNKMLEELRLERKKLIEDyegkl 252
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAeyswdeidVASAEREIAELEAELERLDAS----- 683
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 253 nkaqsfyERELDTLKRsqlfTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAI 332
Cdd:COG4913 684 -------SDDLAALEE----QLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE 752
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 333 AennvqVLQKQLDDAKEGEMAllskhKEVESELAAARERLQQQASDLVLKashigMLQATQ----MTQEVTIkDLESEkS 408
Cdd:COG4913 753 E-----RFAAALGDAVERELR-----ENLEERIDALRARLNRAEEELERA-----MRAFNRewpaETADLDA-DLESL-P 815
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 409 RVNERLSQLEEERaflrsktqsldeeqkqqileLEKKVNEAKRTQQEYYERELKNLQSRLEEE-------VTQLNEAhsk 481
Cdd:COG4913 816 EYLALLDRLEEDG--------------------LPEYEERFKELLNENSIEFVADLLSKLRRAireikerIDPLNDS--- 872
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 119568573 482 tLEELAWKH----HMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQEL 534
Cdd:COG4913 873 -LKRIPFGPgrylRLEARPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRL 928
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
284-938 |
3.12e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 41.75 E-value: 3.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 284 EADLRKEFQGQEAILRKTIGKLKTELQMVQDEagslldkcqkLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEves 363
Cdd:pfam12128 274 IASRQEERQETSAELNQLLRTLDDQWKEKRDE----------LNGELSAADAAVAKDRSELEALEDQHGAFLDADIE--- 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 364 ELAAARERLQQQASDL-VLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILEL 442
Cdd:pfam12128 341 TAAADQEQLPSWQSELeNLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQAL 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 443 EKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAhSKTLEELawkhhMAIEAVHSNAIRDKKKLqmdleEQHNKDKLN 522
Cdd:pfam12128 421 ESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQA-TATPELL-----LQLENFDERIERAREEQ-----EAANAEVER 489
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 523 LEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMvrkSEQGLGSAEGLIaslqdsqERLQNELDLTKDSL-KETKDAL 601
Cdd:pfam12128 490 LQSELRQARKRRDQASEALRQASRRLEERQSALDEL---ELQLFPQAGTLL-------HFLRKEAPDWEQSIgKVISPEL 559
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 602 L---NVEGELEQERQQHEETIAAMkeeeKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEdKKSAMSQLLQLkdre 678
Cdd:pfam12128 560 LhrtDLDPEVWDGSVGGELNLYGV----KLDLKRIDVPEWAASEEELRERLDKAEEALQSAREK-QAAAEEQLVQA---- 630
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 679 kNAARDSWQKKVEDLLnqisllkqnleiqlsqsqtslqqlqAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAfQTM 758
Cdd:pfam12128 631 -NGELEKASREETFAR-------------------------TALKNARLDLRRLFDEKQSEKDKKNKALAERKDSA-NER 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 759 EEEKEKEQRALENhlqqKHSAELQSLKDAHRESmegfRIEMEQELQtlrfELEDEGKAMLASLRSEL---NHQHAAAIDL 835
Cdd:pfam12128 684 LNSLEAQLKQLDK----KHQAWLEEQKEQKREA----RTEKQAYWQ----VVEGALDAQLALLKAAIaarRSGAKAELKA 751
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 836 LRHNHHQELAAAKMELERSIDISrRQSKEHICRItdlqEELRHREHHISELDKEVQH--LHENiSALTKELEFKGKEILR 913
Cdd:pfam12128 752 LETWYKRDLASLGVDPDVIAKLK-REIRTLERKI----ERIAVRRQEVLRYFDWYQEtwLQRR-PRLATQLSNIERAISE 825
|
650 660
....*....|....*....|....*
gi 119568573 914 IRSESNQQIRLHEQDlNKRLEKELD 938
Cdd:pfam12128 826 LQQQLARLIADTKLR-RAKLEMERK 849
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
395-496 |
3.27e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.38 E-value: 3.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 395 TQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLD---EEQKQQILELEKKVNEAKRTQQE---------YYERELK 462
Cdd:COG2433 396 EAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEaelEEKDERIERLERELSEARSEERReirkdreisRLDREIE 475
|
90 100 110
....*....|....*....|....*....|....
gi 119568573 463 NLQSRLEEEVTQLNEAHSKtLEELawKHHMAIEA 496
Cdd:COG2433 476 RLERELEEERERIEELKRK-LERL--KELWKLEH 506
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
749-1012 |
4.91e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.08 E-value: 4.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 749 EAHVLAFQTMEEEKEKEQRALENHLQQKHSAElqslkdAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQ 828
Cdd:COG1196 228 ELLLLKLRELEAELEELEAELEELEAELEELE------AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 829 HAAAIDLLRhnhHQELAAAKMELERSIDISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKG 908
Cdd:COG1196 302 QDIARLEER---RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 909 KEILRIRSESNQQIRLHEQDLNKRLEKELDVMTADHLREKNImRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPE 988
Cdd:COG1196 379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE-EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457
|
250 260
....*....|....*....|....
gi 119568573 989 DIQMITELKAMLTERDQIIKKLIE 1012
Cdd:COG1196 458 EEALLELLAELLEEAALLEAALAE 481
|
|
| FPP |
pfam05911 |
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ... |
519-628 |
5.61e-03 |
|
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.
Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 40.81 E-value: 5.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 519 DKLNLEEDKNqLQQELENL---KEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDS-- 593
Cdd:pfam05911 676 NDLKTEENKR-LKEEFEQLkseKENLEVELASCTENLESTKSQLQESEQLIAELRSELASLKESNSLAETQLKCMAESye 754
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 119568573 594 ------------LKETKDALLNVEGELEQERQQHEETIAAMKE-EEKL 628
Cdd:pfam05911 755 dletrlteleaeLNELRQKFEALEVELEEEKNCHEELEAKCLElQEQL 802
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
41-551 |
6.27e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.67 E-value: 6.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 41 HLKMSKKIAQLTKVIYALNTKNDEHESA-IQALKDAHEEEIQQILAETREKILQYKSKVTEELDLRR--------KIQVL 111
Cdd:COG4913 264 YAAARERLAELEYLRAALRLWFAQRRLElLEAELEELRAELARLEAELERLEARLDALREELDELEAqirgnggdRLEQL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 112 ESSLEDHIKMKQQALTEFEAYKHRVEDMQLcAEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLQ 191
Cdd:COG4913 344 EREIERLERELEERERRRARLEALLAALGL-PLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELR 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 192 AAhRREIQELLKSQQDHSASVnkgqekaEELHRMEVESLNKMLEELR-----LERKKLIEDYEGKLnkaqsfyERELDTL 266
Cdd:COG4913 423 EL-EAEIASLERRKSNIPARL-------LALRDALAEALGLDEAELPfvgelIEVRPEEERWRGAI-------ERVLGGF 487
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 267 KRSQLFTAESLQASKEK--EADLRKEFQGQEAILRktigklKTELQMVQDEAGSLLDKcqklqtaLAIAENNVQV-LQKQ 343
Cdd:COG4913 488 ALTLLVPPEHYAAALRWvnRLHLRGRLVYERVRTG------LPDPERPRLDPDSLAGK-------LDFKPHPFRAwLEAE 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 344 L---------DDAKE--------------------GEM---------------------ALLSKHKEVESELAAARER-- 371
Cdd:COG4913 555 LgrrfdyvcvDSPEElrrhpraitragqvkgngtrHEKddrrrirsryvlgfdnraklaALEAELAELEEELAEAEERle 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 372 -LQQQASDLVLKASHIGMLQATQMTQevtiKDLESeksrVNERLSQLEEERAFLRSKTQSLdEEQKQQILELEKKVNEAK 450
Cdd:COG4913 635 aLEAELDALQERREALQRLAEYSWDE----IDVAS----AEREIAELEAELERLDASSDDL-AALEEQLEELEAELEELE 705
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 451 RTQqeyyeRELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAirDKKKLQMDLEEQHNKDKLNLEEDKNQL 530
Cdd:COG4913 706 EEL-----DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL--EERFAAALGDAVERELRENLEERIDAL 778
|
570 580
....*....|....*....|.
gi 119568573 531 QQELENLKEVLEDKLNTANQE 551
Cdd:COG4913 779 RARLNRAEEELERAMRAFNRE 799
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
273-478 |
6.66e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.20 E-value: 6.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 273 TAESLQASKEKEADlrkEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEgem 352
Cdd:COG3883 13 FADPQIQAKQKELS---ELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERRE--- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 353 allskhkEVESELAAA-RERLQQQASDLVLKASHIG-MLQATQMTQEVT------IKDLESEKSRVNERLSQLEEERAFL 424
Cdd:COG3883 87 -------ELGERARALyRSGGSVSYLDVLLGSESFSdFLDRLSALSKIAdadadlLEELKADKAELEAKKAELEAKLAEL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 119568573 425 RSKTQSLDEEQKqqilELEKKVNEAKRTQQEyYERELKNLQSRLEEEVTQLNEA 478
Cdd:COG3883 160 EALKAELEAAKA----ELEAQQAEQEALLAQ-LSAEEAAAEAQLAELEAELAAA 208
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
520-905 |
7.09e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.52 E-value: 7.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 520 KLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQgLGSAEGLIASLQDSQERLqNELDLTKDSLKETKD 599
Cdd:COG4717 79 ELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK-LLQLLPLYQELEALEAEL-AELPERLEELEERLE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 600 ALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLE--IKWTENLRQECSKLREELRlQHEEDKKSAMSQLLQLKDR 677
Cdd:COG4717 157 ELRELEEELEELEAELAELQEELEELLEQLSLATEEELQdlAEELEELQQRLAELEEELE-EAQEELEELEEELEQLENE 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 678 EKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQT 757
Cdd:COG4717 236 LEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEE 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 758 MEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDllR 837
Cdd:COG4717 316 LEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALE--Q 393
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 838 HNHHQELAAAKMELERSIDISRRQSKEHICRIT--DLQEELRHREHHISELDKEVQHLHENISALTKELE 905
Cdd:COG4717 394 AEEYQELKEELEELEEQLEELLGELEELLEALDeeELEEELEELEEELEELEEELEELREELAELEAELE 463
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
400-705 |
8.78e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.14 E-value: 8.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 400 IKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQ-----KQQILELEKKVNEAKRTQQEYyeRELKNLQSRLEEEVTQ 474
Cdd:COG4717 97 LEELEEELEELEAELEELREELEKLEKLLQLLPLYQelealEAELAELPERLEELEERLEEL--RELEEELEELEAELAE 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 475 LNEAHSKTLEELAWKHHMAIEavhsNAIRDKKKLQMDLEEQHNKDKlNLEEDKNQLQQELENLKEVLEDKlnTANQEIGH 554
Cdd:COG4717 175 LQEELEELLEQLSLATEEELQ----DLAEELEELQQRLAELEEELE-EAQEELEELEEELEQLENELEAA--ALEERLKE 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 555 LQDMVRkSEQGLGSAEGLIASLQDSQERLQN--------------ELDLTKDSLKETKDALLNVEGELEQERQQHEETIA 620
Cdd:COG4717 248 ARLLLL-IAAALLALLGLGGSLLSLILTIAGvlflvlgllallflLLAREKASLGKEAEELQALPALEELEEEELEELLA 326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 621 AMKEEEKLKVDKMAHDLE-IKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISL 699
Cdd:COG4717 327 ALGLPPDLSPEELLELLDrIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEE 406
|
....*.
gi 119568573 700 LKQNLE 705
Cdd:COG4717 407 LEEQLE 412
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
209-539 |
9.10e-03 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 40.00 E-value: 9.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 209 SASVNKGQEKAEElHRMEVES-LNKMLEELR--LERKKLIE--DYEGKLNKAQSFYERELDTLKRSQ-----LFTAESLQ 278
Cdd:NF033838 46 PTVTSSGNESQKE-HAKEVEShLEKILSEIQksLDKRKHTQnvALNKKLSDIKTEYLYELNVLKEKSeaeltSKTKKELD 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 279 ASKE--KEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQtaLAIAENNVQVLQKQLDDAKEG------ 350
Cdd:NF033838 125 AAFEqfKKDTLEPGKKVAEATKKVEEAEKKAKDQKEEDRRNYPTNTYKTLE--LEIAESDVEVKKAELELVKEEakeprd 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 351 EMALLSKHKEVESELAAA---------RERLQQQASDLVlkashiGMLQATQMTQEVTIKDLESEKSRVNERLSQL---- 417
Cdd:NF033838 203 EEKIKQAKAKVESKKAEAtrlekiktdREKAEEEAKRRA------DAKLKEAVEKNVATSEQDKPKRRAKRGVLGEpatp 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 418 --EEERAflRSKTQSLDEEQ--------KQQILELEKKVNEAKR--------TQQEYYERELKNLQSRLEEEVTQLNEAH 479
Cdd:NF033838 277 dkKENDA--KSSDSSVGEETlpspslkpEKKVAEAEKKVEEAKKkakdqkeeDRRNYPTNTYKTLELEIAESDVKVKEAE 354
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 480 SKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKE 539
Cdd:NF033838 355 LELVKEEAKEPRNEEKIKQAKAKVESKKAEATRLEKIKTDRKKAEEEAKRKAAEEDKVKE 414
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
65-503 |
9.16e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.14 E-value: 9.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 65 HESAIQALKDAHEE--EIQQILAETREKILQYKSKVTEELDLRRKIQVLESSLEDHIKMKQQALTEFEAYKHRVEDMQLC 142
Cdd:COG4717 66 PELNLKELKELEEElkEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 143 AEAQHVQrivtmsREVEEIRRKfEEKLRSFGQLQVQFEKDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEEL 222
Cdd:COG4717 146 ERLEELE------ERLEELREL-EEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEA 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 223 hRMEVESLNKMLEElrLERKKLIEDYEGKLNKAQSFYerELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTI 302
Cdd:COG4717 219 -QEELEELEEELEQ--LENELEAAALEERLKEARLLL--LIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLL 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 303 GKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLK 382
Cdd:COG4717 294 AREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 119568573 383 AshigMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELK 462
Cdd:COG4717 374 A----LLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELE 449
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 119568573 463 NLQSRLEEEVTQLNEA-HSKTLEELAWKHHMAIEAVHSNAIR 503
Cdd:COG4717 450 ELREELAELEAELEQLeEDGELAELLQELEELKAELRELAEE 491
|
|
| |
