|
Name |
Accession |
Description |
Interval |
E-value |
| HrpA |
COG1643 |
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]; |
1-827 |
0e+00 |
|
HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 441249 [Multi-domain] Cd Length: 836 Bit Score: 937.19 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 1 MTMLPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWCT-GQVLLLSPRRLAARAAAERIAEMIGDEPGGM 79
Cdd:COG1643 7 PPDLPVSAVLPELLAALRAHQVVVLAAPPGAGKTTQLPLALLELGWGAgGRIGMLEPRRLAARAAAERMAEELGEPVGET 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 80 VGYATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFGLALALDAQAALRPDLRIVPMSATL 159
Cdd:COG1643 87 VGYRVRFEDKVSAATRIEVVTEGILLRELQRDPELEGVDTVIFDEFHERSLNADLLLALLLDLQPALRPDLKLLVMSATL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 160 DGARFAALLGDAPVIESEGRIQPLDLRHIGRASEKR-IEDDMAAAIRRALTEEaEGDLLAFLPGVAEIDRTAERVEG-LP 237
Cdd:COG1643 167 DAERFARLLGDAPVIESSGRTYPVEVRYRPLPADERdLEDAVADAVREALAEE-PGDILVFLPGEREIRRTAEALRGrLP 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 238 A--EIHRLHGSLDPAAQRAAIRPSREGRRKVILATSIAETSLTIDGVRIVVDSGLARRPRYDRAAGVTRLVTERASQASA 315
Cdd:COG1643 246 PdtEILPLYGRLSAAEQDRAFAPAPHGRRRIVLATNIAETSLTVPGIRYVIDSGLARIPRYDPRSGVTRLPTERISQASA 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 316 TQRAGRAARQRPGVAYRLWEAAATAGMPPFDPPEILESDLSSLMLDCALWGVNDPATLRWLDPPPASAVDEARRRLIALE 395
Cdd:COG1643 326 NQRAGRAGRLAPGICYRLWSEEDFARRPAFTDPEILRADLASLILELAAWGLGDPEDLPFLDPPPARAIADARALLQELG 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 396 ALDDDGRIAAHGKALAKLPLSPRIAHMLVRGGDMGLVDIAADVAVLLGERGI--GGQDTDLTLRRQRWRRESGKRADAAR 473
Cdd:COG1643 406 ALDADGRLTPLGRALARLPLDPRLARMLLAAAELGCLREAAILAALLSERDPrrGAAGSDLLARLNLWRRLREQQREFLS 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 474 AMArrwarlVPAIHGGGGSSTRPAESQRSTlVAASEHQVGLCLALAFPDRVAKRRSADGaDWVSVGGRGFRLDPLSPLAR 553
Cdd:COG1643 486 YLR------LREWRDLARQLRRLLGEGANE-EPADYEAIGLLLALAYPDRIARRRGEGG-RYLLARGRGAALFPGSPLAK 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 554 EEWLAVGEVQGSAAGARILSAAPIAEADILSLFGHRVQEHRIVRFRSANGGIEALRERRLGAVRLSSGSDDRPDPDAVAG 633
Cdd:COG1643 558 KEWLVAAELVGGAAEARIRLAAPIDPEWLEELAAHLIKRYSEPHWDKKRGRVVARERVRLGALVLVSRPLPGPDPEAARE 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 634 ALRDGVRQGGLSLLPWSDAAMSLRTRAAFA------GIEALSDEALMVTLDDWLPPLLQGKRRLSDIDRSLLSGVLEGLI 707
Cdd:COG1643 638 ALLRALRREGLDLLPWSKAARQLRARVEFLerklgeRWPDVSDEALLATLEDWLAPYLTGVRSLKDLKRLDLLAALRALL 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 708 GWDGKQQLDRLAPADFRSPAGSSHAIDYAAEGGPrVELRVQALFGLAAHPTIGNQHIPLVLSLTSPAGRPIQTTRDLPGF 787
Cdd:COG1643 718 PWEQQQRLDELAPTHLTVPSGSRLPLDYSADGPP-VAVRLQELFGLAETPGVADGRVPVPLHLLSPAGRPLQVTWDLPGF 796
|
810 820 830 840
....*....|....*....|....*....|....*....|
gi 94423371 788 WAGNWRDVAKEMRGRYPRHPWPEDPAAASATLRTKRADAR 827
Cdd:COG1643 797 WRGSYAEVRKELRGRYPKHPWPDDPAAAAPTRRTKRRMPR 836
|
|
| DEAH_box_HrpB |
TIGR01970 |
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but ... |
4-823 |
0e+00 |
|
ATP-dependent helicase HrpB; This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 273901 [Multi-domain] Cd Length: 819 Bit Score: 741.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWCTGQVLLLSPRRLAARAAAERIAEMIGDEPGGMVGYA 83
Cdd:TIGR01970 1 LPIHAVLPALRDALAAHPQVVLEAPPGAGKSTAVPLALLDAPGIGGKIIMLEPRRLAARSAAQRLASQLGEAVGQTVGYR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 84 TRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFGLALALDAQAALRPDLRIVPMSATLDGAR 163
Cdd:TIGR01970 81 VRGENKVSRRTRLEVVTEGILTRMIQDDPELDGVGALIFDEFHERSLDADLGLALALDVQSSLREDLKILAMSATLDGER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 164 FAALLGDAPVIESEGRIQPLDLRHIGRASEKRIEDDMAAAIRRALTEEAeGDLLAFLPGVAEIDRTAERVE---GLPAEI 240
Cdd:TIGR01970 161 LSSLLPDAPVVESEGRSFPVEIRYLPLRGDQRLEDAVSRAVEHALASET-GSILVFLPGQAEIRRVQEQLAerlDSDVLI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 241 HRLHGSLDPAAQRAAIRPSREGRRKVILATSIAETSLTIDGVRIVVDSGLARRPRYDRAAGVTRLVTERASQASATQRAG 320
Cdd:TIGR01970 240 CPLYGELSLAAQDRAIKPDPQGRRKVVLATNIAETSLTIEGIRVVIDSGLARVARFDPKTGITRLETVRISQASATQRAG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 321 RAARQRPGVAYRLWEAAATAGMPPFDPPEILESDLSSLMLDCALWGVNDPATLRWLDPPPASAVDEARRRLIALEALDDD 400
Cdd:TIGR01970 320 RAGRLEPGVCYRLWSEEQHQRLPAQDEPEILQADLSGLALELAQWGAKDPSDLRWLDAPPSVALAAARQLLQRLGALDAQ 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 401 GRIAAHGKALAKLPLSPRIAHMLVRGGDMGLVDIAADVAVLLGERGI-GGQDTDLTLRRQRWRRESgkradaaRAMARRW 479
Cdd:TIGR01970 400 GRLTAHGKAMAALGCHPRLAAMLLSAHSTGLAALACDLAALLEERGLpRQGGADLMNRLHRLQQGR-------QGRGQRA 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 480 ARLVPAIHGGGGSSTRPAEsqrstlvAASEHQVGLCLALAFPDRVAKRRSADGaDWVSVGGRGFRLDPLSPLAREEWLAV 559
Cdd:TIGR01970 473 QQLAKKLRRRLRFSQADSG-------AIASHALGLLLALAFPDRIAKRRGQPG-RYQLANGRGAVLSAEDALAREPWLVA 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 560 GEVQGSAAG--ARILSAAPIAEADILSLFGHRVQEHRIVRFRSANGGIEALRERRLGAVRLSSGSDDRPDPDAVAGALRD 637
Cdd:TIGR01970 545 ADLGEGQGKtaARILLAAPVDEALLRQVLPDLVVQVDQVDWDETKGRLVAERQLRIGQLVLKSEPLANPDPAQIAAALLN 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 638 GVRQGGLSLLPWSDAAMSLRTRAAFA-------GIEALSDEALMVTLDDWLPPLLQGKRRLSDIDRSLLSGVLEGLIGWD 710
Cdd:TIGR01970 625 YVRQKGLSALNWTEELRQWRARVACArswdpeaDWPDLSDEALLARLETWLEPYLAGVTSLSGLQELDLYDALKNLLPWE 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 711 GKQQLDRLAPADFRSPAGSSHAIDYAAEGGPRVELRVQALFGLAAHPTIGNQHIPLVLSLTSPAGRPIQTTRDLPGFWAG 790
Cdd:TIGR01970 705 LQQALDALLPTHWPVPTGNFIAIRYSLDGPPLLAVRLQELFGLAESPRVAQGRVPLTLELLSPAQRPLQVTRDLASFWAG 784
|
810 820 830
....*....|....*....|....*....|...
gi 94423371 791 NWRDVAKEMRGRYPRHPWPEDPAAASATLRTKR 823
Cdd:TIGR01970 785 AYREVKKEMKGRYPKHVWPDDPANAAPTKRTKP 817
|
|
| PRK11664 |
PRK11664 |
ATP-dependent RNA helicase HrpB; Provisional |
1-823 |
0e+00 |
|
ATP-dependent RNA helicase HrpB; Provisional
Pssm-ID: 236950 [Multi-domain] Cd Length: 812 Bit Score: 657.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 1 MTMLPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWCTGQVLLLSPRRLAARAAAERIAEMIGDEPGGMV 80
Cdd:PRK11664 1 MSSLPVAAVLPELLTALKTAPQVLLKAPTGAGKSTWLPLQLLQHGGINGKIIMLEPRRLAARNVAQRLAEQLGEKPGETV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 81 GYATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFGLALALDAQAALRPDLRIVPMSATLD 160
Cdd:PRK11664 81 GYRMRAESKVGPNTRLEVVTEGILTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 161 GARFAALLGDAPVIESEGRIQPLDLRHIGRASEKRIEDDMAAAIRRALTEEAeGDLLAFLPGVAEIDRTAERVEGLPAE- 239
Cdd:PRK11664 161 NDRLQQLLPDAPVIVSEGRSFPVERRYQPLPAHQRFDEAVARATAELLRQES-GSLLLFLPGVGEIQRVQEQLASRVASd 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 240 --IHRLHGSLDPAAQRAAIRPSREGRRKVILATSIAETSLTIDGVRIVVDSGLARRPRYDRAAGVTRLVTERASQASATQ 317
Cdd:PRK11664 240 vlLCPLYGALSLAEQQKAILPAPAGRRKVVLATNIAETSLTIEGIRLVVDSGLERVARFDPKTGLTRLVTQRISQASMTQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 318 RAGRAARQRPGVAYRLWEAAATAGMPPFDPPEILESDLSSLMLDCALWGVNDPATLRWLDPPPASAVDEARRRLIALEAL 397
Cdd:PRK11664 320 RAGRAGRLEPGICLHLYSKEQAERAAAQSEPEILHSDLSGLLLELLQWGCHDPAQLSWLDQPPAAALAAAKRLLQQLGAL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 398 DDDGRIAAHGKALAKLPLSPRIAHMLVRGGDMG--LVDIAADVAVLLGERGIGGQdTDLTL---RRQR-WRRESgkrada 471
Cdd:PRK11664 400 DGQGRLTARGRKMAALGNDPRLAAMLVAAKEDDeaALATAAKLAAILEEPPRSGS-SDLGValsRKQPhWQQRA------ 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 472 aramarrwARLVPAIHGGGGSstrpaesqrstlvaASEHQVGLCLALAFPDRVAKRRSADGADWVSvGGRGFRLDPLSPL 551
Cdd:PRK11664 473 --------QQLLKRLNVRGGE--------------ADSSLIAPLLALAFPDRIARRRGQDGRYQLA-NGMGAMLDADDAL 529
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 552 AREEWL-AVGEVQGSAAG-ARILSAAPIAEADILSLFGHRVQEHRIVRFRSANGGIEALRERRLGAVRLSSGSDDRPDPD 629
Cdd:PRK11664 530 SRHEWLiAPLLLQGSASPdARILLALPLDIDELVQRCPQLVQQSDTVEWDEAKGTLRAWRRLQIGQLTVKVQPLAKPSEE 609
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 630 AVAGALRDGVRQGGLSLLPWSDAAMSLRTRAAFA-------GIEALSDEALMVTLDDWLPPLLQGKRRLSDIDRSLLSGV 702
Cdd:PRK11664 610 ELHQALLNWIRRKGLSVLNWTPEAEQLRLRLLCAakwlpeyDWPAVDDESLLASLETWLLPHMTGVRSLRGLKSLNIAQA 689
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 703 LEGLIGWDGKQQLDRLAPADFRSPAGSSHAIDYAAEGGPRVELRVQALFGLAAHPTIGNQHIPLVLSLTSPAGRPIQTTR 782
Cdd:PRK11664 690 LRGLLDWPQRQRLDSELPTHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEAQSPTIAQGRVPLVLELLSPAQRPLQITR 769
|
810 820 830 840
....*....|....*....|....*....|....*....|.
gi 94423371 783 DLPGFWAGNWRDVAKEMRGRYPRHPWPEDPAAASATLRTKR 823
Cdd:PRK11664 770 DLAAFWQGAYREVQKEMKGRYPKHVWPDDPANTAPTRRTKK 810
|
|
| HrpB_C |
pfam08482 |
ATP-dependent helicase C-terminal; This domain is found near the C-terminus of bacterial ... |
687-811 |
3.54e-58 |
|
ATP-dependent helicase C-terminal; This domain is found near the C-terminus of bacterial ATP-dependent helicases such as HrpB.
Pssm-ID: 430021 [Multi-domain] Cd Length: 126 Bit Score: 194.19 E-value: 3.54e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 687 GKRRLSDIDRSLLSGVLEGLIGWDGKQQLDRLAPADFRSPAGSSHAIDYAAEGG-PRVELRVQALFGLAAHPTIGNQHIP 765
Cdd:pfam08482 1 GVRSLADLKRLDLLAALRALLPWEQQQRLDRLAPEHLTVPSGSRIRIDYSAEGGaPVLAVRLQELFGLAETPRIAGGRVP 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 94423371 766 LVLSLTSPAGRPIQTTRDLPGFWAGNWRDVAKEMRGRYPRHPWPED 811
Cdd:pfam08482 81 LTLHLLSPAGRPVQVTRDLASFWAGSYAEVRKEMRGRYPKHPWPED 126
|
|
| SF2_C_RHA |
cd18791 |
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A ... |
185-334 |
5.64e-57 |
|
C-terminal helicase domain of the RNA helicase A (RHA) family helicases; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family members are DEAD-like helicases belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350178 [Multi-domain] Cd Length: 171 Bit Score: 192.75 E-value: 5.64e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 185 LRHIGRASEKRIEDD---MAAAIRRALTEEAEGDLLAFLPGVAEIDRTAERVEGLPA-------EIHRLHGSLDPAAQRA 254
Cdd:cd18791 12 LELLGISSEKEDPDYvdaAVRLILQIHRTEEPGDILVFLPGQEEIERLCELLREELLspdlgklLVLPLHSSLPPEEQQR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 255 AIRPSREGRRKVILATSIAETSLTIDGVRIVVDSGLARRPRYDRAAGVTRLVTERASQASATQRAGRAARQRPGVAYRLW 334
Cdd:cd18791 92 VFEPPPPGVRKVVLATNIAETSITIPGVVYVIDSGLVKEKVYDPRTGLSSLVTVWISKASAEQRAGRAGRTRPGKCYRLY 171
|
|
| PRK11131 |
PRK11131 |
ATP-dependent RNA helicase HrpA; Provisional |
4-432 |
7.72e-55 |
|
ATP-dependent RNA helicase HrpA; Provisional
Pssm-ID: 182986 [Multi-domain] Cd Length: 1294 Bit Score: 206.06 E-value: 7.72e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVaPALLAE--PWCTGQVLLLSPRRLAARAAAERIAEMIGDEPGGMVG 81
Cdd:PRK11131 73 LPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQL-PKICLElgRGVKGLIGHTQPRRLAARTVANRIAEELETELGGCVG 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 82 YATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFgLALALDAQAALRPDLRIVPMSATLDG 161
Cdd:PRK11131 152 YKVRFNDQVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDF-ILGYLKELLPRRPDLKVIITSATIDP 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 162 ARFAALLGDAPVIESEGRIQPLDLRHIGRASEKRIED-DMAAAIRRA---LTEEAEGDLLAFLPGVAEIDRTAERVE--G 235
Cdd:PRK11131 231 ERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTErDQLQAIFDAvdeLGREGPGDILIFMSGEREIRDTADALNklN 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 236 LP-AEIHRLHGSLDPAAQRAAIRPSrEGRRkVILATSIAETSLTIDGVRIVVDSGLARRPRYDRAAGVTRLVTERASQAS 314
Cdd:PRK11131 311 LRhTEILPLYARLSNSEQNRVFQSH-SGRR-IVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQAS 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 315 ATQRAGRAARQRPGVAYRLWEAAATAGMPPFDPPEILESDLSSLMLDCALWGVNDPATLRWLDPPPASAVDEARRRLIAL 394
Cdd:PRK11131 389 ANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEEL 468
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 94423371 395 EALDDDG-----RIAAHGKALAKLPLSPRIAHMLVRGGDMGLV 432
Cdd:PRK11131 469 GAITTDEqasayKLTPLGRQLAQLPVDPRLARMVLEAQKHGCV 511
|
|
| DEXHc_HrpB |
cd17990 |
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA ... |
4-176 |
6.94e-53 |
|
DEXH-box helicase domain of ATP-dependent helicase HrpB; HrpB is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpB belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438711 [Multi-domain] Cd Length: 174 Bit Score: 181.38 E-value: 6.94e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPW-CTGQVLLLSPRRLAARAAAERIAEMIGDEPGGMVGY 82
Cdd:cd17990 1 LPIAAVLPALRAALDAGGQVVLEAPPGAGKTTRVPLALLAELWiAGGKIIVLEPRRVAARAAARRLATLLGEAPGETVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 83 ATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFGLALALDAQAALRPDLRIVPMSATLDGA 162
Cdd:cd17990 81 RVRGESRVGRRTRVEVVTEGVLLRRLQRDPELSGVGAVILDEFHERSLDADLALALLLEVQQLLRDDLRLLAMSATLDGD 160
|
170
....*....|....
gi 94423371 163 RFAALLGDAPVIES 176
Cdd:cd17990 161 GLAALLPEAPVVES 174
|
|
| DEXHc_RHA-like |
cd17917 |
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) ... |
24-175 |
1.34e-30 |
|
DEXH-box helicase domain of DEAD-like helicase RHA family proteins; The RNA helicase A (RHA) family includes RHA, also called DEAH-box helicase 9 (DHX9), DHX8, DHX15-16, DHX32-38, and many others. The RHA family belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438707 [Multi-domain] Cd Length: 159 Bit Score: 117.95 E-value: 1.34e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 24 VLVAPPGAGKTTAVAPALLAEPWCTGQ---VLLLSPRRLAARAAAERIAEMIGDEPGGMVGYATRMDSRQSTRTRLLVLT 100
Cdd:cd17917 5 VIVGETGSGKTTQVPQFLLEDGLAKGGkgrIVCTQPRRIAAISVAERVAEERGEKLGEEVGYQIRFESKTSSKTRIKFCT 84
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 94423371 101 EGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFgLALALDAQAALRPDLRIVPMSATLDGARFAALLGDAPVIE 175
Cdd:cd17917 85 DGILLRELLSDPLLSGYSHVILDEAHERSLDTDF-LLGLLKDLLRKRPDLKVILMSATLDAEKFSSYFGGAPVIH 158
|
|
| DEXHc_DHX29 |
cd17975 |
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of ... |
4-174 |
2.22e-23 |
|
DEXH-box helicase domain of DEAH-box helicase 29; DEAH-box helicase 29 (DHX29) is a part of the 43S pre-initiation complex involved in translation initiation of mRNAs with structured 5'-UTRs. DHX29 is part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350733 [Multi-domain] Cd Length: 183 Bit Score: 98.06 E-value: 2.22e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVA----PALLAEPWCTGQ--VLLLSPRRLAARAAAERIAEMIGDE-- 75
Cdd:cd17975 1 LPVFKHRESILETLKRHRVVVVAGETGSGKSTQVPqfllEDLLLNGGTAQKcnIVCTQPRRISAMSLATRVCEELGCEsg 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 76 PGGM---VGYATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFgLALALDAQAALRPDLRI 152
Cdd:cd17975 81 PGGKnslCGYQIRMESRTGEATRLLYCTTGVLLRKLQEDGLLSSISHIIVDEVHERSVQSDF-LLIILKEILHKRSDLHL 159
|
170 180
....*....|....*....|..
gi 94423371 153 VPMSATLDGARFAALLGDAPVI 174
Cdd:cd17975 160 ILMSATVDCEKFSSYFTHCPIL 181
|
|
| DEXHc_DHX33 |
cd17978 |
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA ... |
4-174 |
5.47e-23 |
|
DEXH-box helicase domain of DEAH-box helicase 33; DEAH-box helicase 33 (DHX33) stimulates RNA polymerase I transcription of the 47S precursor rRNA. DHX33 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438710 [Multi-domain] Cd Length: 178 Bit Score: 96.65 E-value: 5.47e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWCTGQVLLLS-PRRLAARAAAERIAEMIGDEPGGMVGY 82
Cdd:cd17978 1 LPIYSARKRLLEELRKHDTVIIIGETGSGKTTQIPQYLYEAGFARGGMIGITqPRRVAAVSVAKRVAEEMGVELGQLVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 83 ATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSD--FGLALALDAQAALR--PDLRIVPMSAT 158
Cdd:cd17978 81 SVRFDDVTSEETRIKYMTDGMLLREAIGDPLLSKYSVIILDEAHERTVHTDvlFGLVKSAQRRRKEQklSPLKVIIMSAT 160
|
170
....*....|....*.
gi 94423371 159 LDGARFAALLGDAPVI 174
Cdd:cd17978 161 LDADLFSEYFNGAPVL 176
|
|
| DEXHc_DHX38 |
cd17983 |
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as ... |
4-173 |
1.13e-21 |
|
DEXH-box helicase domain of DEAH-box helicase 38; DEAH-box helicase 38 (DHX38, also known as PRP16) is involved in pre-mRNA splicing. DHX38 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350741 [Multi-domain] Cd Length: 173 Bit Score: 92.91 E-value: 1.13e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWC-TGQVLLLSPRRLAARAAAERIAEMIGDEPGGMVGY 82
Cdd:cd17983 1 LPIFAVRQELLNVIRDNNVVIVVGETGSGKTTQLTQYLHEDGYTdYGMIGCTQPRRVAAMSVAKRVSEEMGVELGEEVGY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 83 ATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSD--FGlalALDAQAALRPDLRIVPMSATLD 160
Cdd:cd17983 81 AIRFEDCTSENTVIKYMTDGILLRESLRDPDLDKYSAIIMDEAHERSLNTDvlFG---LLREVVARRRDLKLIVTSATMD 157
|
170
....*....|...
gi 94423371 161 GARFAALLGDAPV 173
Cdd:cd17983 158 ADKFADFFGNVPI 170
|
|
| DEXHc_DHX30 |
cd17976 |
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an ... |
4-174 |
2.25e-21 |
|
DEXH-box helicase domain of DEAH-box helicase 30; DEAH-box helicase 30 (DHX30) plays an important role in the assembly of the mitochondrial large ribosomal subunit. DHX30 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350734 [Multi-domain] Cd Length: 178 Bit Score: 92.16 E-value: 2.25e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVaPALLAEPWCTGQ------VLLLSPRRLAARAAAERIAEMIGDEPG 77
Cdd:cd17976 1 LPVDSHKESILSAIEQNPVVVISGDTGCGKTTRI-PQFILEDYVLRGrgarcnVVITQPRRISAVSVAQRVAHELGPNLR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 78 GMVGYATRMDSRQSTRT-RLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFgLALALDAQAALRPDLRIVPMS 156
Cdd:cd17976 80 RNVGYQVRLESRPPPRGgALLFCTVGVLLKKLQSNPRLEGVSHVIVDEVHERDVNTDF-LLILLKGVLQLNPELRVVLMS 158
|
170
....*....|....*...
gi 94423371 157 ATLDGARFAALLGDAPVI 174
Cdd:cd17976 159 ATGDNQRLSRYFGGCPVV 176
|
|
| DEXHc_DHX57 |
cd17985 |
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the ... |
4-174 |
2.50e-21 |
|
DEXH-box helicase domain of DEAH-box helicase 57; DEAH-box helicase 57 (DHX57) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350743 [Multi-domain] Cd Length: 177 Bit Score: 91.83 E-value: 2.50e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVaPALLAEPWCTG------QVLLLSPRRLAARAAAERIAEMIGDEPG 77
Cdd:cd17985 1 LPAWQERETILELLEKHQVLVISGMTGCGKTTQI-PQFILDNSLQGpplpvaNIICTQPRRISAISVAERVAQERAERVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 78 GMVGYATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFgLALALDAQAALRPDLRIVPMSA 157
Cdd:cd17985 80 QSVGYQIRLESVKSSATRLLYCTTGVLLRRLEGDPTLQGVTHVIVDEVHERTEESDF-LLLVLKDLMVQRPDLKVILMSA 158
|
170
....*....|....*..
gi 94423371 158 TLDGARFAALLGDAPVI 174
Cdd:cd17985 159 TLNAELFSDYFNSCPVI 175
|
|
| DEXHc_DHX34 |
cd17979 |
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in ... |
4-175 |
1.84e-20 |
|
DEXH-box helicase domain of DEAH-box helicase 34; DEAH-box helicase 34 (DHX34) plays a role in the nonsense-mediated decay (NMD), a surveillance mechanism that degrades aberrant mRNAs. DHX34 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350737 [Multi-domain] Cd Length: 170 Bit Score: 89.42 E-value: 1.84e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWctGQVLLLSPRRLAARAAAERIAEMIGDEPGGMVGYA 83
Cdd:cd17979 1 LPIAQYREKIIELLKTHQVVIVAGDTGCGKSTQVPQYLLAAGF--RHIACTQPRRIACISLAKRVAFESLNQYGSKVAYQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 84 TRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFgLALALDAQAALRPDLRIVPMSATLDGAR 163
Cdd:cd17979 79 IRFERTRTLATKLLFLTEGLLLRQIQRDASLPQYNVLILDEVHERHLHGDF-LLGVLRCLLRLRPDLKLILMSATINIEL 157
|
170
....*....|..
gi 94423371 164 FAALLGDAPVIE 175
Cdd:cd17979 158 FSGYFEGAPVVQ 169
|
|
| DEXHc_DHX16 |
cd17974 |
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably ... |
4-173 |
2.39e-20 |
|
DEXH-box helicase domain of DEAH-box helicase 16; DEAH-box helicase 16 (DHX16) is probably involved in pre-mRNA splicing. DHX16 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350732 [Multi-domain] Cd Length: 174 Bit Score: 89.10 E-value: 2.39e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWC--TGQVLLLSPRRLAARAAAERIAEMIGDEPGGMVG 81
Cdd:cd17974 1 LPVYPYRDDLLAAVKEHQVLIIVGETGSGKTTQIPQYLHEAGYTkgGGKIGCTQPRRVAAMSVAARVAEEMGVKLGNEVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 82 YATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSD--FGlalALDAQAALRPDLRIVPMSATL 159
Cdd:cd17974 81 YSIRFEDCTSEKTVLKYMTDGMLLREFLTEPDLASYSVMIIDEAHERTLHTDilFG---LVKDIARFRPDLKLLISSATM 157
|
170
....*....|....
gi 94423371 160 DGARFAALLGDAPV 173
Cdd:cd17974 158 DAEKFSAFFDDAPI 171
|
|
| DEXHc_HrpA |
cd17989 |
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA ... |
4-175 |
4.09e-20 |
|
DEXH-box helicase domain of ATP-dependent RNA helicase HrpA; HrpA is part of the HrpB-HrpA two-partner secretion (TPS) system, a secretion pathway important to the secretion of large virulence-associated proteins. HrpA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350747 [Multi-domain] Cd Length: 173 Bit Score: 88.28 E-value: 4.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVaPALLAEPW--CTGQVLLLSPRRLAARAAAERIAEMIGDEPGGMVG 81
Cdd:cd17989 1 LPVSQKRDEIAKAIAENQVVIIAGETGSGKTTQL-PKICLELGrgIRGLIGHTQPRRLAARSVAERIAEELKTELGGAVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 82 YATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFgLALALDAQAALRPDLRIVPMSATLDG 161
Cdd:cd17989 80 YKVRFTDQTSDETCVKLMTDGILLAETQTDRYLRAYDTIIIDEAHERSLNIDF-LLGYLKQLLPRRPDLKVIITSATIDA 158
|
170
....*....|....
gi 94423371 162 ARFAALLGDAPVIE 175
Cdd:cd17989 159 ERFSRHFNNAPIIE 172
|
|
| DEXHc_DHX8 |
cd17971 |
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as ... |
4-174 |
3.42e-19 |
|
DEXH-box helicase domain of DEAH-box helicase 8; DEAH-box helicase 8 (DHX8 ,also known as pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22) acts late in the splicing of pre-mRNA and mediates the release of the spliced mRNA from spliceosomes. DHX8 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350729 [Multi-domain] Cd Length: 179 Bit Score: 86.00 E-value: 3.42e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWCT-GQVLLLSPRRLAARAAAERIAEMIGDEPGGMVGY 82
Cdd:cd17971 6 LPIYKLKEQLIQAVHDNQILVVIGETGSGKTTQITQYLAEAGYTSrGKIGCTQPRRVAAMSVAKRVAEEFGCCLGQEVGY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 83 ATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSD--FGlalALDAQAALRPDLRIVPMSATLD 160
Cdd:cd17971 86 TIRFEDCTSPETVIKYMTDGMLLRECLIDPDLSQYSVIMLDEAHERTIHTDvlFG---LLKKTVQKRPDLKLIVTSATLD 162
|
170
....*....|....
gi 94423371 161 GARFAALLGDAPVI 174
Cdd:cd17971 163 AVKFSQYFYEAPIF 176
|
|
| DEXHc_DHX15 |
cd17973 |
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA ... |
4-174 |
2.51e-17 |
|
DEXH-box helicase domain of DEAH-box helicase 15; DEAH-box helicase 15 (DHX15) is a pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. DHX15 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438709 [Multi-domain] Cd Length: 187 Bit Score: 80.92 E-value: 2.51e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTA----VAPALLAEPWCTgQVLLLSPRRLAARAAAERIAEMIGDEPGGM 79
Cdd:cd17973 13 LPVWEQKEDFLKLLKNNQILVLVGETGSGKTTQipqfVLDDELPHQPKK-LVACTQPRRVAAMSVAQRVAEEMDVKLGEE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 80 VGYATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSD--FGlalALDAQAALRPDLRIVPMSA 157
Cdd:cd17973 92 VGYSIRFEDCSSAKTILKYMTDGMLLREAMSDPLLSRYSVIILDEAHERTLATDilMG---LLKEVVRRRPDLKLIVMSA 168
|
170
....*....|....*..
gi 94423371 158 TLDGARFAALLGDAPVI 174
Cdd:cd17973 169 TLDAGKFQKYFDNAPLL 185
|
|
| DEXHc_DHX35 |
cd17980 |
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and ... |
4-164 |
1.60e-16 |
|
DEXH-box helicase domain of DEAH-box helicase 35; DHX35 plays a role in colorectal cancers and seems to be associated with risk to thyroid cancers. It also has been shown to positively regulate poxviruses, such as Myxoma virus. DEAH-box helicase 35 (DHX35) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350738 [Multi-domain] Cd Length: 185 Bit Score: 78.28 E-value: 1.60e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWCTG--QVLLLSPRRLAARAAAERIAEMIGDEPGGMVG 81
Cdd:cd17980 1 LPVFKLRNHILYLVENYQTIVIVGETGCGKSTQIPQYLAEAGWTAGgrVVGCTQPRRVAAVTVAGRVAEEMGAVLGHEVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 82 YATRMDSRQST-RTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFgLALALDAQAALRPDLRIVPMSATLD 160
Cdd:cd17980 81 YCIRFDDCTDPqATRIKFLTDGMLVREMMLDPLLTKYSVIMLDEAHERTLYTDI-LIGLLKKIQKKRGDLRLIVASATLD 159
|
....
gi 94423371 161 GARF 164
Cdd:cd17980 160 AEKF 163
|
|
| DEXHc_DHX9 |
cd17972 |
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ... |
4-175 |
1.72e-16 |
|
DEXH-box helicase domain of DEAH-box helicase 9; DEAH-box helicase 9 (DHX9, also known as ATP-dependent RNA helicase A or RHA and leukophysin or LKP) plays an important role in many cellular processes, including regulation of DNA replication, transcription, translation, microRNA biogenesis, RNA processing and transport, and maintenance of genomic stability. DHX9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350730 [Multi-domain] Cd Length: 234 Bit Score: 79.49 E-value: 1.72e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWCTGQ-----VLLLSPRRLAARAAAERIAEMIGDEPGG 78
Cdd:cd17972 59 LPVKKFREEILEAISNNPVVIIRGATGCGKTTQVPQYILDDFIQNDRaaecnIVVTQPRRISAVSVAERVAFERGEEVGK 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 79 MVGYATRMDS-RQSTRTRLLVLTEGIFVRRIQDDpeLTGISAVLFDEVHERGLDSDFgLALALDAQAALRPDLRIVPMSA 157
Cdd:cd17972 139 SCGYSVRFESvLPRPHASILFCTVGVLLRKLEAG--IRGISHVIVDEIHERDINTDF-LLVVLRDVVQAYPDLRVILMSA 215
|
170
....*....|....*...
gi 94423371 158 TLDGARFAALLGDAPVIE 175
Cdd:cd17972 216 TIDTSMFCEYFFNCPVIE 233
|
|
| DEXHc_DHX40 |
cd17984 |
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the ... |
4-174 |
7.27e-15 |
|
DEXH-box helicase domain of DEAH-box helicase 40; DEAH-box helicase 40 (DHX40) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350742 [Multi-domain] Cd Length: 178 Bit Score: 73.35 E-value: 7.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVaPALLAEPWCT--GQVLLLSPRRLAARAAAERIAEMIGDEPGGMVG 81
Cdd:cd17984 1 LPIQKQRKKLVQAVRDNSFLIVTGNTGSGKTTQL-PKYLYEAGFSqhGMIGVTQPRRVAAISVAQRVAEEMKCTLGSKVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 82 YATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSD--FG--LALALDAQAALRPDLRIVPMSA 157
Cdd:cd17984 80 YQVRFDDCSSKETAIKYMTDGCLLRHILADPNLTKYSVIILDEAHERSLTTDilFGllKKLFQEKSPNRKEHLKVVVMSA 159
|
170
....*....|....*..
gi 94423371 158 TLDGARFAALLGDAPVI 174
Cdd:cd17984 160 TLELAKLSAFFGNCPVF 176
|
|
| DEXHc_YTHDC2 |
cd17987 |
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) ... |
4-174 |
2.68e-14 |
|
DEXH-box helicase domain of YTH domain containing 2; YTH domain containing 2 (YTHDC2) regulates mRNA translation and stability via binding to N6-methyladenosine, a modified RNA nucleotide enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. YTHDC2 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350745 [Multi-domain] Cd Length: 176 Bit Score: 71.78 E-value: 2.68e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWCTG---QVLLLSPRRLAARAAAERIAEMIGDEPGGMV 80
Cdd:cd17987 1 LPVFEKQEQIVRIIKENKVVLIVGETGSGKTTQIPQFLLDDCYANGipcRIFCTQPRRLAAIAVAERVAAERGEKIGQTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 81 GYATRMDSRQSTRTRLLVLTEGIFVRRIQD-DPELTGISAVLFDEVHERGLDSDFgLALALDAQAALRPDLRIVPMSATL 159
Cdd:cd17987 81 GYQIRLESRVSPKTLLTFCTNGVLLRTLMAgDSALSTVTHVIVDEVHERDRFSDF-LLTKLRDILQKHPNLKLILSSAAL 159
|
170
....*....|....*
gi 94423371 160 DGARFAALLGDAPVI 174
Cdd:cd17987 160 DVNLFIRYFGSCPVI 174
|
|
| DEXHc_DHX36 |
cd17981 |
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as ... |
4-175 |
3.05e-14 |
|
DEXH-box helicase domain of DEAH-box helicase 36; DEAH-box helicase 36 (DHX36, also known as G4-resolvase 1 or G4R1, MLE-like protein 1 and RNA helicase associated with AU-rich element or RHAU) unwinds a G4-quadruplex in human telomerase RNA. DHX36 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350739 [Multi-domain] Cd Length: 180 Bit Score: 71.80 E-value: 3.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWCTG-----QVLLLSPRRLAARAAAERIAEMIGDEP-- 76
Cdd:cd17981 1 LPSYGMKQEIINMIDNNQVTVISGETGCGKTTQVTQFILDDAIERGkgsscRIVCTQPRRISAISVAERVAAERAESCgl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 77 GGMVGYATRMDSRQS-TRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFgLALALDAQAALRPDLRIVPM 155
Cdd:cd17981 81 GNSTGYQIRLESRKPrKQGSILYCTTGIVLQWLQSDPHLSNVSHLVLDEIHERNLQSDV-LMGIVKDLLPFRSDLKVILM 159
|
170 180
....*....|....*....|
gi 94423371 156 SATLDGARFAALLGDAPVIE 175
Cdd:cd17981 160 SATLNAEKFSDYFNNCPMIH 179
|
|
| HA2 |
smart00847 |
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino ... |
393-466 |
2.65e-12 |
|
Helicase associated domain (HA2) Add an annotation; This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 214852 [Multi-domain] Cd Length: 82 Bit Score: 63.06 E-value: 2.65e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 94423371 393 ALEALDDDGRIAAHGKALAKLPLSPRIAHMLVRGGDMGLVDIAADVAVLLGERGI--GGQDTDLTLRRQRWRRESG 466
Cdd:smart00847 1 ELGALDDDGRLTPLGRKMAELPLDPRLAKMLLAAAEFGCLDEILTIVAMLSVGDPrpKEKREDADAARRRFADPES 76
|
|
| HELICc |
smart00490 |
helicase superfamily c-terminal domain; |
227-324 |
1.58e-11 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 197757 [Multi-domain] Cd Length: 82 Bit Score: 60.69 E-value: 1.58e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 227 DRTAERVEGLPAEIHRLHGSLDPAAQRAAIRPSREGRRKVILATSIAETSLTIDGVRIVVDSGLarrprydraagvtrlv 306
Cdd:smart00490 1 EELAELLKELGIKVARLHGGLSQEEREEILDKFNNGKIKVLVATDVAERGLDLPGVDLVIIYDL---------------- 64
|
90
....*....|....*...
gi 94423371 307 teRASQASATQRAGRAAR 324
Cdd:smart00490 65 --PWSPASYIQRIGRAGR 80
|
|
| DEXHc_DHX37 |
cd17982 |
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the ... |
4-159 |
5.91e-11 |
|
DEXH-box helicase domain of DEAH-box helicase 37; DHX37 plays a role in the development of the human nervous system and has been linked to schizophrenia. It also negatively regulates poxviruses such as Myxoma virus. DEAH-box helicase 37 (DHX37) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350740 [Multi-domain] Cd Length: 191 Bit Score: 62.37 E-value: 5.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVaPALLAE-------PWCTGQVLLLSPRRLAARAAAERIAEMIGDeP 76
Cdd:cd17982 1 LPILAEEQEIMEAINENPVVIICGETGSGKTTQV-PQFLYEagfgspeSDNPGMIGITQPRRVAAVSMAKRVAEELNV-F 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 77 GGMVGYATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSD--FG--------LALALDAQAAL 146
Cdd:cd17982 79 GKEVSYQIRYDSTVSENTKIKFMTDGVLLKEIQTDFLLRKYSVIIIDEAHERSVNTDilIGmlsrivplRAKLYLQDQTV 158
|
170
....*....|...
gi 94423371 147 RPdLRIVPMSATL 159
Cdd:cd17982 159 KP-LKLVIMSATL 170
|
|
| Helicase_C |
pfam00271 |
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, ... |
202-324 |
8.85e-11 |
|
Helicase conserved C-terminal domain; The Prosite family is restricted to DEAD/H helicases, whereas this domain family is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase.
Pssm-ID: 459740 [Multi-domain] Cd Length: 109 Bit Score: 59.53 E-value: 8.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 202 AAIRRALTEEAEGDLLAFLPGVAEIDRTA-ERVEGLPaeIHRLHGSLDPAAQRAAIRPSREGRRKVILATSIAETSLTID 280
Cdd:pfam00271 4 EALLELLKKERGGKVLIFSQTKKTLEAELlLEKEGIK--VARLHGDLSQEEREEILEDFRKGKIDVLVATDVAERGLDLP 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 94423371 281 GVRIVVDSGLARRPrydraagvtrlvterasqASATQRAGRAAR 324
Cdd:pfam00271 82 DVDLVINYDLPWNP------------------ASYIQRIGRAGR 107
|
|
| DEXHc_TDRD9 |
cd17988 |
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also ... |
4-175 |
3.72e-10 |
|
DEXH-box helicase domain of tudor domain containing 9; Tudor domain containing 9 (TDRD9, also known as HIG-1or NET54 or C14orf75) is a part of the nuclear PIWI-interacting RNA (piRNA) pathway essential for transposon silencing and male fertility TDRD9 belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350746 [Multi-domain] Cd Length: 180 Bit Score: 59.82 E-value: 3.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVAPPGAGKTTAVAPALLAEPWCTG---QVLLLSPRRLAARAAAERIAEMIGDEPGGMV 80
Cdd:cd17988 1 LPIYAKREEILSLIEANSVVIIKGATGCGKTTQLPQFILDHYYKRGkycNIVVTQPRRIAAISIARRVSQEREWTLGSLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 81 GYATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFGLALALDAQAALRPDLRIVPMSATLD 160
Cdd:cd17988 81 GYQVGLERPASEETRLIYCTTGVLLQKLINNKTLTEYTHIILDEVHERDQELDFLLLVVRRLLRTNSRHVKIILMSATIS 160
|
170
....*....|....*....
gi 94423371 161 GARFAALLG----DAPVIE 175
Cdd:cd17988 161 CKEFADYFTtpnnPAYVFE 179
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
17-188 |
2.19e-09 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 57.89 E-value: 2.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 17 LRASSSAVLVAPPGAGKTTAVAPALLAEPWCT--GQVLLLSPRRLAARAAAERIAEMIGDEPGG----MVGYATRMDSRQ 90
Cdd:smart00487 21 LSGLRDVILAAPTGSGKTLAALLPALEALKRGkgGRVLVLVPTRELAEQWAEELKKLGPSLGLKvvglYGGDSKREQLRK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 91 --STRTRLLVLTEGIFVRRIQDDP-ELTGISAVLFDEVHERgLDSDFGlALALDAQAALRPDLRIVPMSATLDGA--RFA 165
Cdd:smart00487 101 leSGKTDILVTTPGRLLDLLENDKlSLSNVDLVILDEAHRL-LDGGFG-DQLEKLLKLLPKNVQLLLLSATPPEEieNLL 178
|
170 180
....*....|....*....|...
gi 94423371 166 ALLGDAPVIESEGRIQPLDLRHI 188
Cdd:smart00487 179 ELFLNDPVFIDVGFTPLEPIEQF 201
|
|
| HA2 |
pfam04408 |
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in ... |
387-439 |
2.71e-09 |
|
Helicase associated domain (HA2); This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Pssm-ID: 461295 [Multi-domain] Cd Length: 104 Bit Score: 55.32 E-value: 2.71e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 94423371 387 ARRRLIALEALDDDGRIAAHGKALAKLPLSPRIAHMLVRGGDMGLVDIAADVA 439
Cdd:pfam04408 1 ALELLYYLGALDEDGELTPLGRKMAELPLDPRLAKMLLAAAELGCLDEVLTIV 53
|
|
| DEXQc_DQX1 |
cd17986 |
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 ... |
4-175 |
2.46e-08 |
|
DEXQ-box helicase domain of DEAQ-box RNA dependent ATPase 1; DEAQ-box RNA dependent ATPase 1 (DQX1) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350744 [Multi-domain] Cd Length: 177 Bit Score: 54.52 E-value: 2.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 4 LPIHAVLPDLLTTLRASSSAVLVA-PPGAGKTTAV----APALLAEPWCTGQVLLLSPRRLAARAAAERIAEMIGDEPGG 78
Cdd:cd17986 1 LPIWAAKFTFLEQLESPSGIVLVSgEPGSGKSTQVpqwcAEFALSRGFQKGQVTVTQPHPLAARSLALRVADEMDLNLGH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 79 MVGYATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFgLALALDAQAALRPDLRIVPMSAT 158
Cdd:cd17986 81 EVGYSIPQEDCTGPNTILRFCWDRLLLQEMTSTPLLGAWGVVVLDEAQERSVASDS-LLGLLKDVRLQRPELRVVVVTSP 159
|
170
....*....|....*..
gi 94423371 159 LDGARFAALLGDAPVIE 175
Cdd:cd17986 160 ALEPKLRAFWGNPPVVH 176
|
|
| DEXHc_DHX32 |
cd17977 |
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the ... |
70-175 |
6.77e-05 |
|
DEXH-box helicase domain of DEAH-box helicase 32; DEAH-box helicase 32 (DHX32) belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350735 [Multi-domain] Cd Length: 176 Bit Score: 44.43 E-value: 6.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 70 EM---IGDEpggmVGYATRMDSRQSTRTRLLVLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSDFgLALALDAQAAL 146
Cdd:cd17977 72 EMdvnIGHE----VGYVIPFENCCTNETILRYCTDDMLLREMMSDPLLESYGVIILDDAHERTVSTDV-LLGLLKDVLLS 146
|
90 100
....*....|....*....|....*....
gi 94423371 147 RPDLRIVPMSATLDGARFAALLGDAPVIE 175
Cdd:cd17977 147 RPELKLVIITCPHLSSKLLSYYGNVPLIE 175
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
18-328 |
1.19e-04 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 45.79 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 18 RASSSAVLVAPPGAGKTTaVAPALLAEPWCTGQVLLLSPRRLAARAAAERIAEMIGDEPGGmvgyatrmDSRQSTRTRLL 97
Cdd:COG1061 98 RGGGRGLVVAPTGTGKTV-LALALAAELLRGKRVLVLVPRRELLEQWAEELRRFLGDPLAG--------GGKKDSDAPIT 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 98 VLTEGIFVRRIQDDPELTGISAVLFDEVHERGLDSdfglalaLDAQAALRPDLRIVPMSAT---LDGARFAALLGDAPVI 174
Cdd:COG1061 169 VATYQSLARRAHLDELGDRFGLVIIDEAHHAGAPS-------YRRILEAFPAAYRLGLTATpfrSDGREILLFLFDGIVY 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 175 E-------SEGRIQPLDL--RHIGRASEKRIEDDMAAAIRRALTEEAEGDL----------------LAFLPGVAEIDRT 229
Cdd:COG1061 242 EyslkeaiEDGYLAPPEYygIRVDLTDERAEYDALSERLREALAADAERKDkilrellrehpddrktLVFCSSVDHAEAL 321
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 230 AERVEGLPAEIHRLHGSLDPAAQRAAIRPSREGRRKVILATSIAETSLTIDGVRIVVdsglarrprydraagvtrLVTER 309
Cdd:COG1061 322 AELLNEAGIRAAVVTGDTPKKEREEILEAFRDGELRILVTVDVLNEGVDVPRLDVAI------------------LLRPT 383
|
330
....*....|....*....
gi 94423371 310 ASQASATQRAGRAARQRPG 328
Cdd:COG1061 384 GSPREFIQRLGRGLRPAPG 402
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
22-160 |
1.47e-03 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 40.30 E-value: 1.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 22 SAVLVAPPGAGKTTA-VAPAL--LAEPWCTGQVLLLSPRRLAARAAAERIAEMiGDEPGGMVGYATRMDSRQSTRTRL-- 96
Cdd:pfam00270 16 DVLVQAPTGSGKTLAfLLPALeaLDKLDNGPQALVLAPTRELAEQIYEELKKL-GKGLGLKVASLLGGDSRKEQLEKLkg 94
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 94423371 97 ---LVLTEGIFVRRIQDDPELTGISAVLFDEVHeRGLDSDFGlALALDAQAALRPDLRIVPMSATLD 160
Cdd:pfam00270 95 pdiLVGTPGRLLDLLQERKLLKNLKLLVLDEAH-RLLDMGFG-PDLEEILRRLPKKRQILLLSATLP 159
|
|
| DEXHc_Ski2 |
cd17921 |
DEXH-box helicase domain of DEAD-like helicase Ski2 family proteins; Ski2-like RNA helicases ... |
21-177 |
2.36e-03 |
|
DEXH-box helicase domain of DEAD-like helicase Ski2 family proteins; Ski2-like RNA helicases play an important role in RNA degradation, processing, and splicing pathways. They belong to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350679 [Multi-domain] Cd Length: 181 Bit Score: 39.94 E-value: 2.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 21 SSAVLVAPPGAGKTTaVAPALLAEPWCT--GQVLLLSPRRLAARAAAERIAEMIGDEPG--GMVGYATRMDSRQSTRTRL 96
Cdd:cd17921 18 DSVLVSAPTSSGKTL-IAELAILRALATsgGKAVYIAPTRALVNQKEADLRERFGPLGKnvGLLTGDPSVNKLLLAEADI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 97 LVLTEGIFVRRIQDDPELTG--ISAVLFDEVHERGlDSDFGLALALDAQAALR--PDLRIVPMSATLDGAR-FAALLGDA 171
Cdd:cd17921 97 LVATPEKLDLLLRNGGERLIqdVRLVVVDEAHLIG-DGERGVVLELLLSRLLRinKNARFVGLSATLPNAEdLAEWLGVE 175
|
....*.
gi 94423371 172 PVIESE 177
Cdd:cd17921 176 DLIRFD 181
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
21-158 |
3.32e-03 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 38.92 E-value: 3.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 94423371 21 SSAVLVAPPGAGKTTAVAPALLAEPWCTG-QVLLLSPRRLAARAAAeriaEMIGDE--PGGMVGYATRMDS---RQSTRT 94
Cdd:cd00046 2 ENVLITAPTGSGKTLAALLAALLLLLKKGkKVLVLVPTKALALQTA----ERLRELfgPGIRVAVLVGGSSaeeREKNKL 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 94423371 95 R---LLVLTEGIFVRRIQ--DDPELTGISAVLFDEVHERGLDSDFGLALALDAQAALRPDLRIVPMSAT 158
Cdd:cd00046 78 GdadIIIATPDMLLNLLLreDRLFLKDLKLIIVDEAHALLIDSRGALILDLAVRKAGLKNAQVILLSAT 146
|
|
| |
