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Conserved domains on  [gi|56471934|gb|EAL49461|]
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lipid phosphate phosphatase, putative [Entamoeba histolytica HM-1:IMSS]

Protein Classification

phosphatase PAP2 family protein( domain architecture ID 10130247)

type 2 phosphatidic acid phosphatase (PAP2) family protein similar to mammalian phospholipid phosphatases that catalyzes the conversion of phosphatidic acid to diacylglycerol

EC:  3.1.3.-
Gene Ontology:  GO:0006644|GO:0008195|GO:0046839
PubMed:  12447906

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 45-215 1.04e-46

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


:

Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 153.53  E-value: 1.04e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934  45 PSYHYSKHEN-TFTRNMTITIDFFIPLICIILLCLKNH-YISGLFNSILSFIFNDSLNGTITQLYKIFAGRPRPFYFNGC 122
Cdd:cd03390   1 PSISYPFAESeTVPTWLLVIISVGIPLLVIILISLFFRrSLWDLHTSLLGLLLSVSLNGVITNVLKNYAGRPRPDFLARC 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934 123 NPS---------------------LYTCTKSFPSGHSSFSMAGLLFLSLFLYFYFKKSNIHlNSLSSVFFCGLPSFLAII 181
Cdd:cd03390  81 FPDggtpsdtlvgidicctgdpgvLKEGRKSFPSGHSSFAFAGLGFLSLYLAGKLHIFDPR-GSSWRLLLALLPLLLAIL 159

                       170       180       190
                ....*....|....*....|....*....|....
gi 56471934 182 IAVTRTRDHYHHFSDILGGSILGGFVAIISFFST 215
Cdd:cd03390 160 VAVSRTRDYRHHFSDVIAGSLIGLIIAYLSYRQY 193
 
Name Accession Description Interval E-value
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 45-215 1.04e-46

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 153.53  E-value: 1.04e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934  45 PSYHYSKHEN-TFTRNMTITIDFFIPLICIILLCLKNH-YISGLFNSILSFIFNDSLNGTITQLYKIFAGRPRPFYFNGC 122
Cdd:cd03390   1 PSISYPFAESeTVPTWLLVIISVGIPLLVIILISLFFRrSLWDLHTSLLGLLLSVSLNGVITNVLKNYAGRPRPDFLARC 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934 123 NPS---------------------LYTCTKSFPSGHSSFSMAGLLFLSLFLYFYFKKSNIHlNSLSSVFFCGLPSFLAII 181
Cdd:cd03390  81 FPDggtpsdtlvgidicctgdpgvLKEGRKSFPSGHSSFAFAGLGFLSLYLAGKLHIFDPR-GSSWRLLLALLPLLLAIL 159

                       170       180       190
                ....*....|....*....|....*....|....
gi 56471934 182 IAVTRTRDHYHHFSDILGGSILGGFVAIISFFST 215
Cdd:cd03390 160 VAVSRTRDYRHHFSDVIAGSLIGLIIAYLSYRQY 193
PLN02715 PLN02715
lipid phosphate phosphatase
 12-223 1.97e-17

lipid phosphate phosphatase


Pssm-ID: 178317 [Multi-domain]  Cd Length: 327  Bit Score: 79.71  E-value: 1.97e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934   12 KRKIDIIITFIVFVLSKLFGLLPPFKMETPHNHPS-YHYSKHENTFTRNMTITIDFFIPLICIILLCLKNHYISGLFNSI 90
Cdd:PLN02715  46 KHKHDWIILVILIAIEIGLNLISPFYRYVGKDMMTdLKYPFKDNTVPIWSVPVYAVLLPIILFVCFYLKRRCVYDLHHSI 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934   91 LSFIFNDSLNGTITQLYKIFAGRPRPFYFNGCNP---SLYTCT----------------KSFPSGHSSFSMAGLLFLSLF 151
Cdd:PLN02715 126 LGLLFAVLITGVITDSIKVATGRPRPNFYWRCFPdgkELYDALggvichgkaaevkeghKSFPSGHTSWSFAGLTFLSLY 205

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 56471934  152 LYFYFKKSNI--HLNSLSSVFFcglPSFLAIIIAVTRTRDHYHHFSDILGGSILGGFVAIISFFSTFQRFYTEE 223
Cdd:PLN02715 206 LSGKIKAFNGegHVAKLCLVIF---PLLAACLVGISRVDDYWHHWQDVFAGALIGILVAAFCYRQFYPNPYHEE 276
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 99-216 5.95e-15

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 68.99  E-value: 5.95e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934    99 LNGTITQLYKIFAGRPRPFYFNGCNP------SLYTCTKSFPSGHSSFSMAGLLFLSLFLYFYFKKSNihlnslssVFFC 172
Cdd:pfam01569   8 LAGLLSSVLKDYFGRPRPFFLLLEGGlvpapsTLPGLGYSFPSGHSATAFALALLLALLLRRLRKIVR--------VLLA 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 56471934   173 GLPSFLAIIIAVTRTRDHYHHFSDILGGSILGGFVAIISFFSTF 216
Cdd:pfam01569  80 LLLLVLALLVGLSRLYLGVHFPSDVLAGALIGILLALLVYRLVP 123
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 17-213 1.02e-11

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 61.98  E-value: 1.02e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934  17 IIITFIVFVLSKLFGLLPPFKMETPHNHPSYHYSKHENTFTRNMTITIDFFIPLICIILLCLKNHYISGLFNSILSFIFN 96
Cdd:COG0671   2 LLALLLALLLLLLLLADLLALALLALLLLLALLLLLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALL 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934  97 DSLNGTITQLYKIFAGRPRPFYFNGCNPSLYTCTK-SFPSGHSSFSMAGLlflslflyfyfkksnIHLNSLSSVFFCGLP 175
Cdd:COG0671  82 LLLLLLLLLLLKYLFGRPRPFVVPDLELLLGTAGGySFPSGHAAAAFALA---------------LVLALLLPRRWLAAL 146

                       170       180       190
                ....*....|....*....|....*....|....*....
gi 56471934 176 SF-LAIIIAVTRTRDHYHHFSDILGGSILGGFVAIISFF 213
Cdd:COG0671 147 LLaLALLVGLSRVYLGVHYPSDVLAGALLGLAIALLLLA 185
acidPPc smart00014
Acid phosphatase homologues;
93-212 1.89e-11

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 59.28  E-value: 1.89e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934     93 FIFNDSLNGTItqlyKIFAGRPRPFYFNGCNPSLYT-------CTKSFPSGHSSFSMAGLLFLslflyfyfkkSNIHLNS 165
Cdd:smart00014   4 AVVSQLFNGVI----KNYFGRPRPFFLSIGDACCTPnflltleAGYSFPSGHTAFAFAFALFL----------LLYLPAR 69

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 56471934    166 LSSVFFCGLPSFLAIIIAVTRTRDHYHHFSDILGGSILGGFVAIISF 212
Cdd:smart00014  70 AGRKLLIFLLLLLALVVGFSRVYLGAHWPSDVLAGSLLGILIAAVLF 116
 
Name Accession Description Interval E-value
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 45-215 1.04e-46

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 153.53  E-value: 1.04e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934  45 PSYHYSKHEN-TFTRNMTITIDFFIPLICIILLCLKNH-YISGLFNSILSFIFNDSLNGTITQLYKIFAGRPRPFYFNGC 122
Cdd:cd03390   1 PSISYPFAESeTVPTWLLVIISVGIPLLVIILISLFFRrSLWDLHTSLLGLLLSVSLNGVITNVLKNYAGRPRPDFLARC 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934 123 NPS---------------------LYTCTKSFPSGHSSFSMAGLLFLSLFLYFYFKKSNIHlNSLSSVFFCGLPSFLAII 181
Cdd:cd03390  81 FPDggtpsdtlvgidicctgdpgvLKEGRKSFPSGHSSFAFAGLGFLSLYLAGKLHIFDPR-GSSWRLLLALLPLLLAIL 159

                       170       180       190
                ....*....|....*....|....*....|....
gi 56471934 182 IAVTRTRDHYHHFSDILGGSILGGFVAIISFFST 215
Cdd:cd03390 160 VAVSRTRDYRHHFSDVIAGSLIGLIIAYLSYRQY 193
PLN02715 PLN02715
lipid phosphate phosphatase
 12-223 1.97e-17

lipid phosphate phosphatase


Pssm-ID: 178317 [Multi-domain]  Cd Length: 327  Bit Score: 79.71  E-value: 1.97e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934   12 KRKIDIIITFIVFVLSKLFGLLPPFKMETPHNHPS-YHYSKHENTFTRNMTITIDFFIPLICIILLCLKNHYISGLFNSI 90
Cdd:PLN02715  46 KHKHDWIILVILIAIEIGLNLISPFYRYVGKDMMTdLKYPFKDNTVPIWSVPVYAVLLPIILFVCFYLKRRCVYDLHHSI 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934   91 LSFIFNDSLNGTITQLYKIFAGRPRPFYFNGCNP---SLYTCT----------------KSFPSGHSSFSMAGLLFLSLF 151
Cdd:PLN02715 126 LGLLFAVLITGVITDSIKVATGRPRPNFYWRCFPdgkELYDALggvichgkaaevkeghKSFPSGHTSWSFAGLTFLSLY 205

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 56471934  152 LYFYFKKSNI--HLNSLSSVFFcglPSFLAIIIAVTRTRDHYHHFSDILGGSILGGFVAIISFFSTFQRFYTEE 223
Cdd:PLN02715 206 LSGKIKAFNGegHVAKLCLVIF---PLLAACLVGISRVDDYWHHWQDVFAGALIGILVAAFCYRQFYPNPYHEE 276
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 90-212 3.80e-17

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 74.80  E-value: 3.80e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934  90 ILSFIFNDSLNGTITQLYKIFAGRPRPFYFNGCNP-----SLYTCTKSFPSGHSSFSMAGLLFLSLFLYFYFKKsnihln 164
Cdd:cd01610   5 ALLLLLALLAGLLLTGVLKYLFGRPRPYFLLRCGPdgdplLLTEGGYSFPSGHAAFAFALALFLALLLPRRLLR------ 78

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 56471934 165 slssVFFCGLPSFLAIIIAVTRTRDHYHHFSDILGGSILGGFVAIISF 212
Cdd:cd01610  79 ----LLLGLLLLLLALLVGLSRVYLGVHYPSDVLAGALLGILVALLVL 122
PLN02250 PLN02250
lipid phosphate phosphatase
 16-216 5.46e-16

lipid phosphate phosphatase


Pssm-ID: 215139  Cd Length: 314  Bit Score: 75.73  E-value: 5.46e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934   16 DIIITFIVFVLSKLFGLLPPF------KMETPHNHPSyhyskHENTFTRNMTITIDFFIPLICIILLCLKNHYISGLFNS 89
Cdd:PLN02250  25 DWLILLLLVVIEVVLNVIEPFhrfvgkDMLTDLSYPL-----QDNTIPFWAVPLIAILLPFAVILVYYFIRRDVYDLHHA 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934   90 ILSFIFNDSLNGTITQLYKIFAGRPRPFYFNGCNP----------SLYTCT----------KSFPSGHSSFSMAGLLFLS 149
Cdd:PLN02250 100 ILGLLFSVLITGVITDAIKDAVGRPRPDFFWRCFPdgkgvfhpvtTDVLCTgaksvikeghKSFPSGHTSWSFAGLGFLS 179

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 56471934  150 LFLYFYFK--KSNIHLNSLSSVFfcgLPSFLAIIIAVTRTRDHYHHFSDILGGSILGGFVAIISFFSTF 216
Cdd:PLN02250 180 LYLSGKIRvfDRRGHVAKLCIVF---LPLLVAALVGVSRVDDYWHHWQDVFAGALIGLTVASFCYLQFF 245
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 86-210 2.86e-15

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


Pssm-ID: 239479  Cd Length: 150  Bit Score: 70.74  E-value: 2.86e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934  86 LFNSILSFIFNDSLNGTITQLYKIFAGRPRPFYFNGCNPSLYTCT-------------------------KSFPSGHSSF 140
Cdd:cd03384   2 LYRFVGVFLFGLFATQLLTDLGKYVTGRLRPHFLDVCKPNYTDLTcsldhqyiadctcctgdpdlirearLSFPSGHASL 81

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 56471934 141 SMAGLLFLSLFLYFYFKKSNIHLnsLSSVF-FCGLpsFLAIIIAVTRTRDHYHHFSDILGGSILGGFVAII 210
Cdd:cd03384  82 SMYAAVFLALYLQARLKLRGSRL--LRPLLqFLLL--ALALYVGLSRISDYKHHWSDVLAGALLGSVIALF 148
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 99-216 5.95e-15

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 68.99  E-value: 5.95e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934    99 LNGTITQLYKIFAGRPRPFYFNGCNP------SLYTCTKSFPSGHSSFSMAGLLFLSLFLYFYFKKSNihlnslssVFFC 172
Cdd:pfam01569   8 LAGLLSSVLKDYFGRPRPFFLLLEGGlvpapsTLPGLGYSFPSGHSATAFALALLLALLLRRLRKIVR--------VLLA 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 56471934   173 GLPSFLAIIIAVTRTRDHYHHFSDILGGSILGGFVAIISFFSTF 216
Cdd:pfam01569  80 LLLLVLALLVGLSRLYLGVHFPSDVLAGALIGILLALLVYRLVP 123
PLN02731 PLN02731
Putative lipid phosphate phosphatase
 16-223 2.09e-12

Putative lipid phosphate phosphatase


Pssm-ID: 178332  Cd Length: 333  Bit Score: 65.44  E-value: 2.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934   16 DIIITFIVFVLSKLFGLLPPF-KMETPHNHPSYHYSKHENTFTRNMTITIDFFIPLICIILLCLKNHYISGLFNSILSFI 94
Cdd:PLN02731  44 DWIILVLLVILECVLLIIHPFyRFVGKDMMTDLSYPLKSNTVPIWSVPVYAMLLPLVIFIFIYFRRRDVYDLHHAVLGLL 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934   95 FNDSLNGTITQLYKIFAGRPRPFYFNGCNP---SLYTCT----------------KSFPSGHSSFSMAGLLFLSLFLYFY 155
Cdd:PLN02731 124 YSVLVTAVLTDAIKNAVGRPRPDFFWRCFPdgkALYDSLgdvichgdksvireghKSFPSGHTSWSFSGLGFLSLYLSGK 203

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934  156 FK--KSNIHLNSLSSVFfcgLPSFLAIIIAVTRTRDHYHHFSDILGGSILGGFVAIISFFSTFQRFYTEE 223
Cdd:PLN02731 204 IQafDGKGHVAKLCIVI---LPLLFAALVGISRVDDYWHHWQDVFAGGLLGLAISTICYLQFFPPPYHTE 270
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 17-213 1.02e-11

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 61.98  E-value: 1.02e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934  17 IIITFIVFVLSKLFGLLPPFKMETPHNHPSYHYSKHENTFTRNMTITIDFFIPLICIILLCLKNHYISGLFNSILSFIFN 96
Cdd:COG0671   2 LLALLLALLLLLLLLADLLALALLALLLLLALLLLLLLLLALLLILLLLLLLLLLLLLLLLLLLRLLALLLLLLLLAALL 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934  97 DSLNGTITQLYKIFAGRPRPFYFNGCNPSLYTCTK-SFPSGHSSFSMAGLlflslflyfyfkksnIHLNSLSSVFFCGLP 175
Cdd:COG0671  82 LLLLLLLLLLLKYLFGRPRPFVVPDLELLLGTAGGySFPSGHAAAAFALA---------------LVLALLLPRRWLAAL 146

                       170       180       190
                ....*....|....*....|....*....|....*....
gi 56471934 176 SF-LAIIIAVTRTRDHYHHFSDILGGSILGGFVAIISFF 213
Cdd:COG0671 147 LLaLALLVGLSRVYLGVHYPSDVLAGALLGLAIALLLLA 185
acidPPc smart00014
Acid phosphatase homologues;
93-212 1.89e-11

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 59.28  E-value: 1.89e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934     93 FIFNDSLNGTItqlyKIFAGRPRPFYFNGCNPSLYT-------CTKSFPSGHSSFSMAGLLFLslflyfyfkkSNIHLNS 165
Cdd:smart00014   4 AVVSQLFNGVI----KNYFGRPRPFFLSIGDACCTPnflltleAGYSFPSGHTAFAFAFALFL----------LLYLPAR 69

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 56471934    166 LSSVFFCGLPSFLAIIIAVTRTRDHYHHFSDILGGSILGGFVAIISF 212
Cdd:smart00014  70 AGRKLLIFLLLLLALVVGFSRVYLGAHWPSDVLAGSLLGILIAAVLF 116
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 61-218 1.03e-09

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239486  Cd Length: 182  Bit Score: 56.08  E-value: 1.03e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934  61 TITIDFFIPLICIILLcLKNHYISGLFnSILSFIFNDSLNGTITQLYkifaGRPRPFYFNGCNPSLYtctkSFPSGHSSF 140
Cdd:cd03392  41 PAVLLIIVLLLALLLL-LKRRRRAALF-LLLALLGGGALNTLLKLLV----QRPRPPLHLLVPEGGY----SFPSGHAMG 110

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 56471934 141 SMAGLLFLSLFLYFYFKKsnihlnSLSSVFFCGLPSFLAIIIAVTRTRDHYHHFSDILGGSILGGFVAIISFFSTFQR 218
Cdd:cd03392 111 ATVLYGFLAYLLARRLPR------RRVRILLLILAAILILLVGLSRLYLGVHYPSDVLAGWLLGLAWLALLILLYRRL 182
PAP2_like_5 cd03394
PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 86-208 2.37e-06

PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239488 [Multi-domain]  Cd Length: 106  Bit Score: 45.01  E-value: 2.37e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 56471934  86 LFNSILSFIFNDSLNGTITQLYKIFAGRPRPFYFNGCNpslytctKSFPSGHSS--FSMAgllflslflyfyfkkSNIHL 163
Cdd:cd03394   1 DREGLLILAEAAALTAAVTEGLKFAVGRARPDGSNNGY-------RSFPSGHTAsaFAAA---------------TFLQY 58

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 56471934 164 NSLSSVFfcGLPSF-LAIIIAVTRTRDHYHHFSDILGGSILGGFVA 208
Cdd:cd03394  59 RYGWRWY--GIPAYaLASLVGASRVVANRHWLSDVLAGAAIGILVG 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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