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Conserved domains on  [gi|925923449|emb|CUF24645|]
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putative transposase [Staphylococcus aureus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
transpos_IS1182 super family cl41317
IS1182 family transposase; Members of this family are transposases of the IS1182 family. ...
 38-122 7.33e-13

IS1182 family transposase; Members of this family are transposases of the IS1182 family. About two-thirds of the members of this family have an extra domain between the middle and the C-terminal domain, about 50 amino acids in size and containing four invariant Cys residues.


The actual alignment was detected with superfamily member NF033551:

Pssm-ID: 468080 [Multi-domain]  Cd Length: 437  Bit Score: 63.88  E-value: 7.33e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925923449  38 DSEFDEFICPNNKRIGFKryayrnDRYSFKRDFKLYECDDCSSCSLRHQCMKpnsKSNKKIMKNYNWEYFKAQINQKLSE 117
Cdd:NF033551 310 DEEDDTYICPAGQRLTFK------TTSREGYREYRFDPEDCRGCPLREQCTK---SKEGRVVTRHIHEDLLEEARARLKT 380


                 ....*
gi 925923449 118 PETKK 122
Cdd:NF033551 381 EEGKE 385
 
Name Accession Description Interval E-value
transpos_IS1182 NF033551
IS1182 family transposase; Members of this family are transposases of the IS1182 family. ...
 38-122 7.33e-13

IS1182 family transposase; Members of this family are transposases of the IS1182 family. About two-thirds of the members of this family have an extra domain between the middle and the C-terminal domain, about 50 amino acids in size and containing four invariant Cys residues.


Pssm-ID: 468080 [Multi-domain]  Cd Length: 437  Bit Score: 63.88  E-value: 7.33e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925923449  38 DSEFDEFICPNNKRIGFKryayrnDRYSFKRDFKLYECDDCSSCSLRHQCMKpnsKSNKKIMKNYNWEYFKAQINQKLSE 117
Cdd:NF033551 310 DEEDDTYICPAGQRLTFK------TTSREGYREYRFDPEDCRGCPLREQCTK---SKEGRVVTRHIHEDLLEEARARLKT 380


                 ....*
gi 925923449 118 PETKK 122
Cdd:NF033551 381 EEGKE 385
DDE_Tnp_1_6 pfam13751
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 45-122 2.19e-06

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.


Pssm-ID: 433453 [Multi-domain]  Cd Length: 125  Bit Score: 43.48  E-value: 2.19e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 925923449   45 ICPNNKRIGFKrYAYRNDRYSFKRDFKLYECDDCSSCSLRHQCMKpnSKSNKKIMKNYNWEYFKAQINQKLSEPETKK 122
Cdd:pfam13751   1 ICPAGKKLTLS-TTYREGGNGYKREVARYRCEDCRGCPLREQCTK--SKKGRVLTIRPELNELLRQARERIKSEAGKA 75
 
Name Accession Description Interval E-value
transpos_IS1182 NF033551
IS1182 family transposase; Members of this family are transposases of the IS1182 family. ...
 38-122 7.33e-13

IS1182 family transposase; Members of this family are transposases of the IS1182 family. About two-thirds of the members of this family have an extra domain between the middle and the C-terminal domain, about 50 amino acids in size and containing four invariant Cys residues.


Pssm-ID: 468080 [Multi-domain]  Cd Length: 437  Bit Score: 63.88  E-value: 7.33e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925923449  38 DSEFDEFICPNNKRIGFKryayrnDRYSFKRDFKLYECDDCSSCSLRHQCMKpnsKSNKKIMKNYNWEYFKAQINQKLSE 117
Cdd:NF033551 310 DEEDDTYICPAGQRLTFK------TTSREGYREYRFDPEDCRGCPLREQCTK---SKEGRVVTRHIHEDLLEEARARLKT 380


                 ....*
gi 925923449 118 PETKK 122
Cdd:NF033551 381 EEGKE 385
DDE_Tnp_1_6 pfam13751
Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. ...
 45-122 2.19e-06

Transposase DDE domain; Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.


Pssm-ID: 433453 [Multi-domain]  Cd Length: 125  Bit Score: 43.48  E-value: 2.19e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 925923449   45 ICPNNKRIGFKrYAYRNDRYSFKRDFKLYECDDCSSCSLRHQCMKpnSKSNKKIMKNYNWEYFKAQINQKLSEPETKK 122
Cdd:pfam13751   1 ICPAGKKLTLS-TTYREGGNGYKREVARYRCEDCRGCPLREQCTK--SKKGRVLTIRPELNELLRQARERIKSEAGKA 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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