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Conserved domains on  [gi|925922897|emb|CUE97163|]
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Phosphoglycerate kinase [Staphylococcus aureus]

Protein Classification

phosphoglycerate kinase( domain architecture ID 10000622)

phosphoglycerate kinase catalyzes the conversion of ATP and 3-phospho-D-glycerate to ADP and 3-phospho-D-glyceroyl phosphate

CATH:  3.40.50.1260
EC:  2.7.2.3
SCOP:  4000818

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Pgk COG0126
3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; 3-phosphoglycerate kinase ...
6-396 0e+00

3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; 3-phosphoglycerate kinase is part of the Pathway/BioSystem: Glycolysis


:

Pssm-ID: 439896  Cd Length: 389  Bit Score: 642.84  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   6 VSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDkAKLTLRPVAEDLSKKL 85
Cdd:COG0126    2 LDDLDLKGKRVLVRVDFNVPLDDGKITDDTRIRAALPTIKYLLEKGAKVILLSHLGRPKGKVD-PKYSLKPVAERLSELL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  86 DKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEdldgKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGIS 165
Cdd:COG0126   81 GKPVKFVDDCIGEEAEAAVAALKPGEVLLLENLRFH----PEEEKNDPEFAKKLASLGDVYVNDAFGTAHRAHASTVGIA 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 166 THLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEE 245
Cdd:COG0126  157 KLLPSAAGFLMEKELEALGKALENPERPFVAILGGAKVSDKIGVIENLLEKVDKLLIGGGMANTFLKAQGYDVGKSLVEE 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 246 DKIDFAKDLLEKH---GDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMG 322
Cdd:COG0126  237 DKIDTAKEILEKAkekGVKIVLPVDVVVADEFSADAERKVVPVDEIPDDWMGLDIGPKTIELFAEVIKDAKTVVWNGPMG 316
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 925922897 323 VFEFSNFAQGTIGVCKAIANLkDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK 396
Cdd:COG0126  317 VFEMEPFAKGTRAVAKAIAES-GAFSVVGGGDTAAAVNKLGLADKFSHVSTGGGASLEFLEGKELPGVEALEDK 389
 
Name Accession Description Interval E-value
Pgk COG0126
3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; 3-phosphoglycerate kinase ...
6-396 0e+00

3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; 3-phosphoglycerate kinase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439896  Cd Length: 389  Bit Score: 642.84  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   6 VSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDkAKLTLRPVAEDLSKKL 85
Cdd:COG0126    2 LDDLDLKGKRVLVRVDFNVPLDDGKITDDTRIRAALPTIKYLLEKGAKVILLSHLGRPKGKVD-PKYSLKPVAERLSELL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  86 DKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEdldgKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGIS 165
Cdd:COG0126   81 GKPVKFVDDCIGEEAEAAVAALKPGEVLLLENLRFH----PEEEKNDPEFAKKLASLGDVYVNDAFGTAHRAHASTVGIA 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 166 THLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEE 245
Cdd:COG0126  157 KLLPSAAGFLMEKELEALGKALENPERPFVAILGGAKVSDKIGVIENLLEKVDKLLIGGGMANTFLKAQGYDVGKSLVEE 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 246 DKIDFAKDLLEKH---GDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMG 322
Cdd:COG0126  237 DKIDTAKEILEKAkekGVKIVLPVDVVVADEFSADAERKVVPVDEIPDDWMGLDIGPKTIELFAEVIKDAKTVVWNGPMG 316
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 925922897 323 VFEFSNFAQGTIGVCKAIANLkDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK 396
Cdd:COG0126  317 VFEMEPFAKGTRAVAKAIAES-GAFSVVGGGDTAAAVNKLGLADKFSHVSTGGGASLEFLEGKELPGVEALEDK 389
pgk PRK00073
phosphoglycerate kinase; Provisional
3-395 0e+00

phosphoglycerate kinase; Provisional


Pssm-ID: 234613  Cd Length: 389  Bit Score: 625.54  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   3 KKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKakLTLRPVAEDLS 82
Cdd:PRK00073   1 KKTLDDLDLKGKRVLVRVDFNVPVKDGKITDDTRIRAALPTIKYLLEKGAKVILLSHLGRPKGEDPE--FSLAPVAKRLS 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  83 KKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEdldgKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNV 162
Cdd:PRK00073  79 ELLGKEVKFVDDCIGEEAREAIAALKDGEVLLLENVRFN----KGEEKNDPELAKKLASLGDVFVNDAFGTAHRAHASTV 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 163 GISTHLETA-AGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGIS 241
Cdd:PRK00073 155 GIAKFLKPAaAGFLMEKELEALGKALENPERPFVAILGGAKVSDKIGVLENLLEKVDKLIIGGGMANTFLKAQGYNVGKS 234
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 242 LLEEDKIDFAKDLLEK---HGDKIVLPVDTKVAKEFSnDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWN 318
Cdd:PRK00073 235 LVEEDLIDTAKELLEKakeKGVKIPLPVDVVVAKEFS-DAEATVVSVDEIPDDWMILDIGPKTIELFAEIIKDAKTIVWN 313
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 925922897 319 GPMGVFEFSNFAQGTIGVCKAIANLKdAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINN 395
Cdd:PRK00073 314 GPMGVFEFENFAKGTKAVAKAIAEST-AFSIIGGGDTAAAVEKLGLADKFSHISTGGGASLEFLEGKELPGVAALEE 389
PGK pfam00162
Phosphoglycerate kinase;
13-385 0e+00

Phosphoglycerate kinase;


Pssm-ID: 425495  Cd Length: 370  Bit Score: 590.11  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   13 GKTVLVRADFNVPLKD-GEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKakLTLRPVAEDLSKKLDKEVVF 91
Cdd:pfam00162   1 GKRVLVRVDFNVPLDDdGKITDDTRIRAALPTIKYLLEKGAKVILMSHLGRPKGKDDK--FSLKPVAERLSELLGKPVKF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   92 VPETRGEKLEAAIKDLKEGDVLLVENTRYEdldgKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETA 171
Cdd:pfam00162  79 ADDCIGPEAEAAIAALKPGEVLLLENVRFY----KEEEKNDPEFAKKLASLADVYVNDAFGTAHRAHASTVGVAKFLPSA 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  172 AGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFA 251
Cdd:pfam00162 155 AGFLMEKELEALSKALENPERPFVAILGGAKVSDKIGVIENLLDKVDKLIIGGGMANTFLKAQGYEIGKSLVEEDKIELA 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  252 KDLLEK---HGDKIVLPVDTKVAKEFSNDAKitVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSN 328
Cdd:pfam00162 235 KELLEKakaKGVKIVLPVDVVVADEFSAEGK--VVDVDEIPDDWMGLDIGPETIELFAEVIKKAKTIVWNGPMGVFEFEN 312
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 925922897  329 FAQGTIGVCKAIANL-KDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGK 385
Cdd:pfam00162 313 FAKGTKAVAKAIAEAtAGAFSIVGGGDTAAAVEKLGLADKFSHISTGGGASLEFLEGK 370
Phosphoglycerate_kinase cd00318
Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the ...
6-395 0e+00

Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level phosphorylation events in the glycolytic pathway. Substrate-level phosphorylation is defined as production of ATP by a process, which is catalyzed by water-soluble enzymes in the cytosol; not involving membranes and ion gradients.


Pssm-ID: 238195  Cd Length: 397  Bit Score: 537.61  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   6 VSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKaKLTLRPVAEDLSKKL 85
Cdd:cd00318    1 IDDLDLKGKRVLVRVDFNVPVDDGKITDDTRIRAALPTIKYLLEQGAKVVLLSHLGRPKGEPNE-KYSLAPVAKALSELL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  86 DKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRY---EDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNV 162
Cdd:cd00318   80 GQPVTFANDCVGPEAEEAVEALKPGDVLLLENVRFypeEEGKRDDDKEADEEFAKKLASLGDVYVNDAFGTAHRAHASMV 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 163 GISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISL 242
Cdd:cd00318  160 GIALLLPSAAGFLMEKELKYLAKALENPERPFVAILGGAKVSDKIQVIENLLDKVDYLIIGGGMAFTFLKAQGMDIGKSL 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 243 LEEDKIDFAKDLLEK---HGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNG 319
Cdd:cd00318  240 FEEDGIELAKSLLEKakaKGVKIVLPVDVVVADKFKADANTKVVTDDGIPDGWMGLDIGPKTIELFAEVIRKAKTIVWNG 319
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 925922897 320 PMGVFEFSNFAQGTIGVCKAIANL--KDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINN 395
Cdd:cd00318  320 PMGVFEFPAFAKGTKAIADAIAAAtkAGAFSIIGGGDTAAAAEKFGLADKISHVSTGGGASLELLEGKELPGVAALEE 397
 
Name Accession Description Interval E-value
Pgk COG0126
3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; 3-phosphoglycerate kinase ...
6-396 0e+00

3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; 3-phosphoglycerate kinase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439896  Cd Length: 389  Bit Score: 642.84  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   6 VSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDkAKLTLRPVAEDLSKKL 85
Cdd:COG0126    2 LDDLDLKGKRVLVRVDFNVPLDDGKITDDTRIRAALPTIKYLLEKGAKVILLSHLGRPKGKVD-PKYSLKPVAERLSELL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  86 DKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEdldgKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGIS 165
Cdd:COG0126   81 GKPVKFVDDCIGEEAEAAVAALKPGEVLLLENLRFH----PEEEKNDPEFAKKLASLGDVYVNDAFGTAHRAHASTVGIA 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 166 THLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEE 245
Cdd:COG0126  157 KLLPSAAGFLMEKELEALGKALENPERPFVAILGGAKVSDKIGVIENLLEKVDKLLIGGGMANTFLKAQGYDVGKSLVEE 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 246 DKIDFAKDLLEKH---GDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMG 322
Cdd:COG0126  237 DKIDTAKEILEKAkekGVKIVLPVDVVVADEFSADAERKVVPVDEIPDDWMGLDIGPKTIELFAEVIKDAKTVVWNGPMG 316
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 925922897 323 VFEFSNFAQGTIGVCKAIANLkDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK 396
Cdd:COG0126  317 VFEMEPFAKGTRAVAKAIAES-GAFSVVGGGDTAAAVNKLGLADKFSHVSTGGGASLEFLEGKELPGVEALEDK 389
pgk PRK00073
phosphoglycerate kinase; Provisional
3-395 0e+00

phosphoglycerate kinase; Provisional


Pssm-ID: 234613  Cd Length: 389  Bit Score: 625.54  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   3 KKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKakLTLRPVAEDLS 82
Cdd:PRK00073   1 KKTLDDLDLKGKRVLVRVDFNVPVKDGKITDDTRIRAALPTIKYLLEKGAKVILLSHLGRPKGEDPE--FSLAPVAKRLS 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  83 KKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEdldgKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNV 162
Cdd:PRK00073  79 ELLGKEVKFVDDCIGEEAREAIAALKDGEVLLLENVRFN----KGEEKNDPELAKKLASLGDVFVNDAFGTAHRAHASTV 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 163 GISTHLETA-AGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGIS 241
Cdd:PRK00073 155 GIAKFLKPAaAGFLMEKELEALGKALENPERPFVAILGGAKVSDKIGVLENLLEKVDKLIIGGGMANTFLKAQGYNVGKS 234
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 242 LLEEDKIDFAKDLLEK---HGDKIVLPVDTKVAKEFSnDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWN 318
Cdd:PRK00073 235 LVEEDLIDTAKELLEKakeKGVKIPLPVDVVVAKEFS-DAEATVVSVDEIPDDWMILDIGPKTIELFAEIIKDAKTIVWN 313
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 925922897 319 GPMGVFEFSNFAQGTIGVCKAIANLKdAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINN 395
Cdd:PRK00073 314 GPMGVFEFENFAKGTKAVAKAIAEST-AFSIIGGGDTAAAVEKLGLADKFSHISTGGGASLEFLEGKELPGVAALEE 389
PGK pfam00162
Phosphoglycerate kinase;
13-385 0e+00

Phosphoglycerate kinase;


Pssm-ID: 425495  Cd Length: 370  Bit Score: 590.11  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   13 GKTVLVRADFNVPLKD-GEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKakLTLRPVAEDLSKKLDKEVVF 91
Cdd:pfam00162   1 GKRVLVRVDFNVPLDDdGKITDDTRIRAALPTIKYLLEKGAKVILMSHLGRPKGKDDK--FSLKPVAERLSELLGKPVKF 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   92 VPETRGEKLEAAIKDLKEGDVLLVENTRYEdldgKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETA 171
Cdd:pfam00162  79 ADDCIGPEAEAAIAALKPGEVLLLENVRFY----KEEEKNDPEFAKKLASLADVYVNDAFGTAHRAHASTVGVAKFLPSA 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  172 AGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFA 251
Cdd:pfam00162 155 AGFLMEKELEALSKALENPERPFVAILGGAKVSDKIGVIENLLDKVDKLIIGGGMANTFLKAQGYEIGKSLVEEDKIELA 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  252 KDLLEK---HGDKIVLPVDTKVAKEFSNDAKitVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSN 328
Cdd:pfam00162 235 KELLEKakaKGVKIVLPVDVVVADEFSAEGK--VVDVDEIPDDWMGLDIGPETIELFAEVIKKAKTIVWNGPMGVFEFEN 312
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 925922897  329 FAQGTIGVCKAIANL-KDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGK 385
Cdd:pfam00162 313 FAKGTKAVAKAIAEAtAGAFSIVGGGDTAAAVEKLGLADKFSHISTGGGASLEFLEGK 370
PRK13962 PRK13962
bifunctional phosphoglycerate kinase/triosephosphate isomerase; Provisional
1-396 0e+00

bifunctional phosphoglycerate kinase/triosephosphate isomerase; Provisional


Pssm-ID: 237572 [Multi-domain]  Cd Length: 645  Bit Score: 566.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   1 MAKKIVSDLDLKGKTVLVRADFNVPLK-DGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKaKLTLRPVAE 79
Cdd:PRK13962   1 MNKKTIRDIDVKGKRVIVRVDFNVPLDeNGNITDDTRIRAALPTIKYLLDHGAKVILVSHLGRPKGEFDP-KFSMAPVAK 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  80 DLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEdldgKKESKNDPELGKYWASLGDVFVNDAFGTAHREHA 159
Cdd:PRK13962  80 RLSELLGKEVIFAKDVIGDDAKKAVAQLKEGDVLLLENVRFH----KEETKNDPEFAKELASLADIYVNDAFGTAHRAHA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 160 SNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIG 239
Cdd:PRK13962 156 STAGVAEYLPAVAGFLMEKEIEFLGKALANPQRPFVAILGGAKVSDKIGVIENLLEKVDKLLIGGGMAYTFLKAKGYEVG 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 240 ISLLEEDKIDFAKDLLEK---HGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVV 316
Cdd:PRK13962 236 KSLVEEDKLDLAKELLAKaeeKGVKLLLPVDSVVAKEFKNDAEHKVVPSDAIPEDWMGLDIGPETIELFAKKIADAKTIV 315
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 317 WNGPMGVFEFSNFAQGTIGVCKAIANlKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK 396
Cdd:PRK13962 316 WNGPMGVFEFDNFAEGTRAVAEAVAE-SGAITIIGGGDSAAAVEKLGFADKMSHISTGGGASLEFLEGKVLPGIACLLDK 394
Phosphoglycerate_kinase cd00318
Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the ...
6-395 0e+00

Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level phosphorylation events in the glycolytic pathway. Substrate-level phosphorylation is defined as production of ATP by a process, which is catalyzed by water-soluble enzymes in the cytosol; not involving membranes and ion gradients.


Pssm-ID: 238195  Cd Length: 397  Bit Score: 537.61  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   6 VSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKaKLTLRPVAEDLSKKL 85
Cdd:cd00318    1 IDDLDLKGKRVLVRVDFNVPVDDGKITDDTRIRAALPTIKYLLEQGAKVVLLSHLGRPKGEPNE-KYSLAPVAKALSELL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  86 DKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRY---EDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNV 162
Cdd:cd00318   80 GQPVTFANDCVGPEAEEAVEALKPGDVLLLENVRFypeEEGKRDDDKEADEEFAKKLASLGDVYVNDAFGTAHRAHASMV 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 163 GISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISL 242
Cdd:cd00318  160 GIALLLPSAAGFLMEKELKYLAKALENPERPFVAILGGAKVSDKIQVIENLLDKVDYLIIGGGMAFTFLKAQGMDIGKSL 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 243 LEEDKIDFAKDLLEK---HGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNG 319
Cdd:cd00318  240 FEEDGIELAKSLLEKakaKGVKIVLPVDVVVADKFKADANTKVVTDDGIPDGWMGLDIGPKTIELFAEVIRKAKTIVWNG 319
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 925922897 320 PMGVFEFSNFAQGTIGVCKAIANL--KDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINN 395
Cdd:cd00318  320 PMGVFEFPAFAKGTKAIADAIAAAtkAGAFSIIGGGDTAAAAEKFGLADKISHVSTGGGASLELLEGKELPGVAALEE 397
PTZ00005 PTZ00005
phosphoglycerate kinase; Provisional
1-396 9.76e-141

phosphoglycerate kinase; Provisional


Pssm-ID: 173310  Cd Length: 417  Bit Score: 407.15  E-value: 9.76e-141
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   1 MAKKIVSDLD--LKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGK-IVLFSHLGKvKEESDKAKLTLRPV 77
Cdd:PTZ00005   3 SNKLGIDDVDdqLKGKRVLIRVDFNVPIKEGVIKDATRIKATLPTIKYLLEQGAKsVVLMSHLGR-PDGRRVEKYSLKPV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  78 AEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYE--------DLDGKKESKNDPELGKYWASL---GDVF 146
Cdd:PTZ00005  82 VPKLEELLGKKVTFLNDCVGPEVEEACANAKNGSVILLENLRFHieeegkgvDANGNKVKADKEEVKKFRKSLtklGDIY 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 147 VNDAFGTAHREHASNVGIStHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGM 226
Cdd:PTZ00005 162 VNDAFGTAHRAHSSMVGVD-LPVKVAGFLMKKELDYFSKALENPQRPFLAILGGAKVADKIQLIKNLLDKVDEMIIGGGM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 227 AYTFLKA-QGKEIGISLLEEDKIDFAKDLLEK---HGDKIVLPVDTKVAKEFSNDAKITVVPSDS-IPADQEGMDIGPNT 301
Cdd:PTZ00005 241 AFTFKKVlDNMPIGKSLFDEEGAKIVKEIMEKakeKNVKIHLPVDFVCADKFDNNANTKVVTDKEgIPDGWMGLDAGPKS 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 302 VKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAI--ANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASL 379
Cdd:PTZ00005 321 IEEFAEAILRAKTIVWNGPQGVFEMPNFAKGSIAMLDAVvkATEKGAITIVGGGDTASLVEKTGAANKVSHVSTGGGASL 400
                        410
                 ....*....|....*..
gi 925922897 380 EYLEGKELPGIKAINNK 396
Cdd:PTZ00005 401 ELLEGKELPGVVALSNK 417
PLN03034 PLN03034
phosphoglycerate kinase; Provisional
1-394 4.04e-136

phosphoglycerate kinase; Provisional


Pssm-ID: 178602 [Multi-domain]  Cd Length: 481  Bit Score: 397.83  E-value: 4.04e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   1 MAKKIVSDL---DLKGKTVLVRADFNVPLKDGE-ITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESdkAKLTLRP 76
Cdd:PLN03034  77 MAKKSVGDLtsaDLKGKKVFVRADLNVPLDDNQnITDDTRIRAAIPTIKYLISNGAKVILSSHLGRPKGVT--PKFSLAP 154
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  77 VAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEdldgKKESKNDPELGKYWASLGDVFVNDAFGTAHR 156
Cdd:PLN03034 155 LVPRLSELLGIQVVKADDCIGPEVEKLVASLPEGGVLLLENVRFY----KEEEKNEPEFAKKLASLADLYVNDAFGTAHR 230
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 157 EHASNVGISTHLE-TAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQG 235
Cdd:PLN03034 231 AHASTEGVTKFLKpSVAGFLLQKELDYLVGAVSNPKRPFAAIVGGSKVSSKIGVIESLLEKCDILLLGGGMIFTFYKAQG 310
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 236 KEIGISLLEEDKIDFAKDLLEK---HGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGA 312
Cdd:PLN03034 311 LSVGSSLVEEDKLELATSLLAKakaKGVSLLLPTDVVIADKFAPDANSKIVPASAIPDGWMGLDIGPDSVKTFNEALDTT 390
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 313 HTVVWNGPMGVFEFSNFAQGTIGVCKAIANL--KDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGI 390
Cdd:PLN03034 391 QTVIWNGPMGVFEFEKFAVGTEAVAKKLAELsgKGVTTIIGGGDSVAAVEKVGVADVMSHISTGGGASLELLEGKELPGV 470

                 ....
gi 925922897 391 KAIN 394
Cdd:PLN03034 471 VALD 474
PLN02282 PLN02282
phosphoglycerate kinase
3-395 3.65e-132

phosphoglycerate kinase


Pssm-ID: 165923  Cd Length: 401  Bit Score: 384.71  E-value: 3.65e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897   3 KKIVSDL---DLKGKTVLVRADFNVPLKDG-EITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESdkAKLTLRPVA 78
Cdd:PLN02282   4 KRSVGTLkeaDLKGKRVFVRVDLNVPLDDNsNITDDTRIRAAVPTIKYLMGHGARVILCSHLGRPKGVT--PKYSLKPLV 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897  79 EDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEdldgKKESKNDPELGKYWASLGDVFVNDAFGTAHREH 158
Cdd:PLN02282  82 PRLSELLGVEVVMANDCIGEEVEKLVAELPEGGVLLLENVRFY----KEEEKNDPEFAKKLASLADVYVNDAFGTAHRAH 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 159 ASNVGISTHLETA-AGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKE 237
Cdd:PLN02282 158 ASTEGVAKYLKPSvAGFLMQKELDYLVGAVANPKKPFAAIVGGSKVSTKIGVIESLLEKVDILLLGGGMIFTFYKAQGYS 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 238 IGISLLEEDKIDFAKDLLEK---HGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHT 314
Cdd:PLN02282 238 VGSSLVEEDKLDLATSLIEKakaKGVSLLLPTDVVIADKFAPDANSKVVPASAIPDGWMGLDIGPDSIKTFSEALDTTKT 317
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 925922897 315 VVWNGPMGVFEFSNFAQGTIGVCKAIANL--KDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKA 392
Cdd:PLN02282 318 IIWNGPMGVFEFEKFAAGTEAIAKKLAELsgKGVTTIIGGGDSVAAVEKVGLADKMSHISTGGGASLELLEGKPLPGVLA 397

                 ...
gi 925922897 393 INN 395
Cdd:PLN02282 398 LDD 400
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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