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Conserved domains on  [gi|899981706|emb|CQD74125|]
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DinI family protein [Yersinia intermedia]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DinI super family cl11630
DinI-like family; This family of short proteins includes DNA-damage-inducible protein I (DinI) ...
 2-79 1.71e-27

DinI-like family; This family of short proteins includes DNA-damage-inducible protein I (DinI) and related proteins. The SOS response, a set of cellular phenomena exhibited by eubacteria, is initiated by various causes that include DNA damage-induced replication arrest, and is positively regulated by the co- protease activity of RecA. Escherichia coli DinI, a LexA-regulated SOS gene product, shuts off the initiation of the SOS response when overexpressed in vivo. Biochemical and genetic studies indicated that DinI physically interacts with RecA to inhibit its co-protease activity. The structure of DinI is known.


The actual alignment was detected with superfamily member PRK10597:

Pssm-ID: 448327  Cd Length: 81  Bit Score: 94.91  E-value: 1.71e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 899981706  2 LRVEVTIDKLNakSFPAGYTNALTEELTSRLSRKFSDLD--VKVRFAGADGLTVLGGASEDKNTVEEILKDTWESADDWF 79
Cdd:PRK10597  1 MRIEVTIAKTS--PLPAGAIDALAGELSRRIQYAFPDNEghVSVRYAAANNLSVIGATKEDKDRISEILQETWESADDWF 78
 
Name Accession Description Interval E-value
PRK10597 PRK10597
DNA damage-inducible protein I; Provisional
 2-79 1.71e-27

DNA damage-inducible protein I; Provisional


Pssm-ID: 182578  Cd Length: 81  Bit Score: 94.91  E-value: 1.71e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 899981706  2 LRVEVTIDKLNakSFPAGYTNALTEELTSRLSRKFSDLD--VKVRFAGADGLTVLGGASEDKNTVEEILKDTWESADDWF 79
Cdd:PRK10597  1 MRIEVTIAKTS--PLPAGAIDALAGELSRRIQYAFPDNEghVSVRYAAANNLSVIGATKEDKDRISEILQETWESADDWF 78
DinI pfam06183
DinI-like family; This family of short proteins includes DNA-damage-inducible protein I (DinI) ...
 17-79 9.98e-24

DinI-like family; This family of short proteins includes DNA-damage-inducible protein I (DinI) and related proteins. The SOS response, a set of cellular phenomena exhibited by eubacteria, is initiated by various causes that include DNA damage-induced replication arrest, and is positively regulated by the co- protease activity of RecA. Escherichia coli DinI, a LexA-regulated SOS gene product, shuts off the initiation of the SOS response when overexpressed in vivo. Biochemical and genetic studies indicated that DinI physically interacts with RecA to inhibit its co-protease activity. The structure of DinI is known.


Pssm-ID: 428810  Cd Length: 63  Bit Score: 84.61  E-value: 9.98e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 899981706  17 PAGYTNALTEELTSRLSRKFSDLDVKVRFAGADGLTVLGGASEDKNTVEEILKDTWESADDWF 79
Cdd:pfam06183  1 PAGAIEALENELTKRIHRLFPDAQVRVRYASANGLSVLGASKEDKERISEILQETWESADDWF 63
 
Name Accession Description Interval E-value
PRK10597 PRK10597
DNA damage-inducible protein I; Provisional
 2-79 1.71e-27

DNA damage-inducible protein I; Provisional


Pssm-ID: 182578  Cd Length: 81  Bit Score: 94.91  E-value: 1.71e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 899981706  2 LRVEVTIDKLNakSFPAGYTNALTEELTSRLSRKFSDLD--VKVRFAGADGLTVLGGASEDKNTVEEILKDTWESADDWF 79
Cdd:PRK10597  1 MRIEVTIAKTS--PLPAGAIDALAGELSRRIQYAFPDNEghVSVRYAAANNLSVIGATKEDKDRISEILQETWESADDWF 78
DinI pfam06183
DinI-like family; This family of short proteins includes DNA-damage-inducible protein I (DinI) ...
 17-79 9.98e-24

DinI-like family; This family of short proteins includes DNA-damage-inducible protein I (DinI) and related proteins. The SOS response, a set of cellular phenomena exhibited by eubacteria, is initiated by various causes that include DNA damage-induced replication arrest, and is positively regulated by the co- protease activity of RecA. Escherichia coli DinI, a LexA-regulated SOS gene product, shuts off the initiation of the SOS response when overexpressed in vivo. Biochemical and genetic studies indicated that DinI physically interacts with RecA to inhibit its co-protease activity. The structure of DinI is known.


Pssm-ID: 428810  Cd Length: 63  Bit Score: 84.61  E-value: 9.98e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 899981706  17 PAGYTNALTEELTSRLSRKFSDLDVKVRFAGADGLTVLGGASEDKNTVEEILKDTWESADDWF 79
Cdd:pfam06183  1 PAGAIEALENELTKRIHRLFPDAQVRVRYASANGLSVLGASKEDKERISEILQETWESADDWF 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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