NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|808669980|emb|CQD05095|]
View 

membrane-flanked domain-containing protein [Mycolicibacterium conceptionense]

Protein Classification

YdbT family protein( domain architecture ID 706656)

YdbT family protein, similar to Bacillus subtilis UPF0699 transmembrane protein YdbT, may contain a Pleckstrin Homology (PH) domain

PubMed:  15493994
SCOP:  3000134

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
YdbT super family cl28701
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 57-172 1.33e-25

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


The actual alignment was detected with superfamily member COG3428:

Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 100.94  E-value: 1.33e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808669980  57 NVLFIVIGAIWLIVVGWLTVWPFLNWWTTHFVITDRRVMFRHGLLTRSGIDIPLARINSVEFRHGLTDRMLRTGTLIIES 136
Cdd:COG3428   38 GGGLLWVLLIALVLLLLLLLVSYLRWRTTRYRITDDRLIVRSGVLSRKRREIPLDRIQSVDVSQPLLHRLFGLGTVRIET 117

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 808669980 137 ASQD----PLEFHDIPRVEQVHSLLYHEVFDTLGSEESPS 172
Cdd:COG3428  118 AGGGesevELDALSVPEAERLRRLLLERAAGAAEEEAEAA 157
 
Name Accession Description Interval E-value
YdbT COG3428
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 57-172 1.33e-25

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 100.94  E-value: 1.33e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808669980  57 NVLFIVIGAIWLIVVGWLTVWPFLNWWTTHFVITDRRVMFRHGLLTRSGIDIPLARINSVEFRHGLTDRMLRTGTLIIES 136
Cdd:COG3428   38 GGGLLWVLLIALVLLLLLLLVSYLRWRTTRYRITDDRLIVRSGVLSRKRREIPLDRIQSVDVSQPLLHRLFGLGTVRIET 117

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 808669980 137 ASQD----PLEFHDIPRVEQVHSLLYHEVFDTLGSEESPS 172
Cdd:COG3428  118 AGGGesevELDALSVPEAERLRRLLLERAAGAAEEEAEAA 157
bPH_2 pfam03703
Bacterial PH domain; Domain found in uncharacterized family of membrane proteins. 1-3 copies ...
 82-157 6.33e-18

Bacterial PH domain; Domain found in uncharacterized family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices. Members of this family have a PH domain like structure.


Pssm-ID: 427450 [Multi-domain]  Cd Length: 78  Bit Score: 73.79  E-value: 6.33e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 808669980   82 WWTTHFVITDRRVMFRHGLLTRSGIDIPLARINSVEFRHGLTDRMLRTGTLIIESASQDP--LEFHDIPRVEQVHSLL 157
Cdd:pfam03703   1 YRATGYTITDRRVVVRSGILGRKRVDIPLERIQDVSLSQSPLQRRLGLGTIVIDTAGGSGvrLPLRDVPDAEELREWL 78
 
Name Accession Description Interval E-value
YdbT COG3428
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 57-172 1.33e-25

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 100.94  E-value: 1.33e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808669980  57 NVLFIVIGAIWLIVVGWLTVWPFLNWWTTHFVITDRRVMFRHGLLTRSGIDIPLARINSVEFRHGLTDRMLRTGTLIIES 136
Cdd:COG3428   38 GGGLLWVLLIALVLLLLLLLVSYLRWRTTRYRITDDRLIVRSGVLSRKRREIPLDRIQSVDVSQPLLHRLFGLGTVRIET 117

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 808669980 137 ASQD----PLEFHDIPRVEQVHSLLYHEVFDTLGSEESPS 172
Cdd:COG3428  118 AGGGesevELDALSVPEAERLRRLLLERAAGAAEEEAEAA 157
bPH_2 pfam03703
Bacterial PH domain; Domain found in uncharacterized family of membrane proteins. 1-3 copies ...
 82-157 6.33e-18

Bacterial PH domain; Domain found in uncharacterized family of membrane proteins. 1-3 copies found in each protein, with each copy flanked by transmembrane helices. Members of this family have a PH domain like structure.


Pssm-ID: 427450 [Multi-domain]  Cd Length: 78  Bit Score: 73.79  E-value: 6.33e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 808669980   82 WWTTHFVITDRRVMFRHGLLTRSGIDIPLARINSVEFRHGLTDRMLRTGTLIIESASQDP--LEFHDIPRVEQVHSLL 157
Cdd:pfam03703   1 YRATGYTITDRRVVVRSGILGRKRVDIPLERIQDVSLSQSPLQRRLGLGTIVIDTAGGSGvrLPLRDVPDAEELREWL 78
YdbS COG3402
Uncharacterized membrane protein YdbS, contains bPH2 (bacterial pleckstrin homology) domain ...
 16-151 1.85e-14

Uncharacterized membrane protein YdbS, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


Pssm-ID: 442629 [Multi-domain]  Cd Length: 143  Bit Score: 66.38  E-value: 1.85e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808669980  16 LHRHPHWKRLIGAVLVLLLITAASAFVAAVVNAMDWqataknvLFIVIGAIWLIV-VGWLTVWPFLNWWTTHFVITDRRV 94
Cdd:COG3402    1 LSPRAVKVWRLRALIGALILLAVLAVLALLLDFPPW-------LGWVLLALVVVLaVLSLVLAPPLRYRRWRYEVREDDL 73

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 808669980  95 MFRHGLLTRSGIDIPLARINSVEFRHGLTDRMLRTGTLIIESAS-QDPLEFHDIPRVE 151
Cdd:COG3402   74 YIRRGVLFRRRTVVPYGRIQHVDTEQGPLERLFGLATVTVTTAGsSGDVTIPGLPEEE 131
YdbT COG3428
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 9-138 5.37e-08

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 51.25  E-value: 5.37e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808669980   9 AADEQVVLHRHPHWkrligavLVLLLITAASAFVAAVVNAMDWQATAKNVLFIVIGAIWLIVVGWLTVWPFLNWWTTHFV 88
Cdd:COG3428  157 AAPEEVLYRLSPRD-------LLLAGLTSGGLLLLLALVGALYSQLADEAGLLLVLLLLLLGWLLSVVGTVLRYYGFRLT 229

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 808669980  89 ITDRRVMFRHGLLTRSGIDIPLARINSVEFRHGLTDRMLRTGTLIIESAS 138
Cdd:COG3428  230 RSGDGLRIRRGLLTRRSVTIPLDRIQAVRIKQPLLRRLFGWARLEVEVAG 279
YdbT COG3428
Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain ...
 79-138 5.04e-05

Uncharacterized membrane protein YdbT, contains bPH2 (bacterial pleckstrin homology) domain [Function unknown];


Pssm-ID: 442654 [Multi-domain]  Cd Length: 410  Bit Score: 42.39  E-value: 5.04e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 808669980  79 FLNWWTTHFVITDRRVMFRHGLLTRSGIDIPLARINSVEFRHGLTDRMLRTGTLIIESAS 138
Cdd:COG3428  325 PLRYRRLGYALTGDYLVVRSGFLTRRTVVVPRDRIQSVRLSQSPFQRRLGLATVRVDTAA 384
bPH_3 pfam14470
Bacterial PH domain; Proteins in this family are distantly related to PH domains.
 87-124 7.50e-03

Bacterial PH domain; Proteins in this family are distantly related to PH domains.


Pssm-ID: 464181  Cd Length: 94  Bit Score: 34.17  E-value: 7.50e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 808669980   87 FVITDRRVMFRH-GLLTRS-GIDIPLARINSVEFRHGLTD 124
Cdd:pfam14470  24 IVVTNKRIIFLDkGMFGGMkFIEIPYKKIKSVSFKKGLFG 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH