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Conserved domains on  [gi|888380757|emb|CMP74738|]
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Conserved hypothetical protein%2C possible antitoxin [Mycobacterium tuberculosis]

Protein Classification

type II toxin-antitoxin system VapB family antitoxin( domain architecture ID 10008555)

type II toxin-antitoxin (TA) system VapB family antitoxin binds to and neutralizes the effect of its cognate VapC toxin; similar to Mycolicibacterium smegmatis antitoxin VapB

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4423 COG4423
Uncharacterized conserved protein [Function unknown];
11-91 1.48e-18

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443538  Cd Length: 83  Bit Score: 72.62  E-value: 1.48e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888380757 11 ALNIKDPEVDRLAAELADRLHTSKTAAIRHALSAQLAFLESRAgdREAQLLDILRtEIWPLLADRSPITKLEREQILGYD 90
Cdd:COG4423   2 ALNIKDPEVDRLARELAALTGESKTEAVRRALEERLARLRRER--RAAPLRERLR-AILERAAALPGLDDRSADEILGYD 78


                .
gi 888380757 91 P 91
Cdd:COG4423  79 E 79
 
Name Accession Description Interval E-value
COG4423 COG4423
Uncharacterized conserved protein [Function unknown];
11-91 1.48e-18

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443538  Cd Length: 83  Bit Score: 72.62  E-value: 1.48e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888380757 11 ALNIKDPEVDRLAAELADRLHTSKTAAIRHALSAQLAFLESRAgdREAQLLDILRtEIWPLLADRSPITKLEREQILGYD 90
Cdd:COG4423   2 ALNIKDPEVDRLARELAALTGESKTEAVRRALEERLARLRRER--RAAPLRERLR-AILERAAALPGLDDRSADEILGYD 78


                .
gi 888380757 91 P 91
Cdd:COG4423  79 E 79
PSK_trans_fac pfam07704
Rv0623-like transcription factor; This entry represents the Rv0623-like family of ...
 11-90 1.17e-15

Rv0623-like transcription factor; This entry represents the Rv0623-like family of transcription factors associated with the PSK operon.


Pssm-ID: 429609  Cd Length: 82  Bit Score: 65.34  E-value: 1.17e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888380757  11 ALNIKDPEVDRLAAELADRLHTSKTAAIRHALSAQLAFLES-RAGDREAQLLDIL-RTEIWPLLADRSPitklerEQILG 88
Cdd:pfam07704  2 ALNIKDPEVDRLARELARRTGESKTEAVRRALEERLARLRRrRAEPLAERLLAIAeRAAALPVLDDRSP------DEILL 75


                 ..
gi 888380757  89 YD 90
Cdd:pfam07704 76 YD 77
 
Name Accession Description Interval E-value
COG4423 COG4423
Uncharacterized conserved protein [Function unknown];
11-91 1.48e-18

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443538  Cd Length: 83  Bit Score: 72.62  E-value: 1.48e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888380757 11 ALNIKDPEVDRLAAELADRLHTSKTAAIRHALSAQLAFLESRAgdREAQLLDILRtEIWPLLADRSPITKLEREQILGYD 90
Cdd:COG4423   2 ALNIKDPEVDRLARELAALTGESKTEAVRRALEERLARLRRER--RAAPLRERLR-AILERAAALPGLDDRSADEILGYD 78


                .
gi 888380757 91 P 91
Cdd:COG4423  79 E 79
PSK_trans_fac pfam07704
Rv0623-like transcription factor; This entry represents the Rv0623-like family of ...
 11-90 1.17e-15

Rv0623-like transcription factor; This entry represents the Rv0623-like family of transcription factors associated with the PSK operon.


Pssm-ID: 429609  Cd Length: 82  Bit Score: 65.34  E-value: 1.17e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888380757  11 ALNIKDPEVDRLAAELADRLHTSKTAAIRHALSAQLAFLES-RAGDREAQLLDIL-RTEIWPLLADRSPitklerEQILG 88
Cdd:pfam07704  2 ALNIKDPEVDRLARELARRTGESKTEAVRRALEERLARLRRrRAEPLAERLLAIAeRAAALPVLDDRSP------DEILL 75


                 ..
gi 888380757  89 YD 90
Cdd:pfam07704 76 YD 77
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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