|
Name |
Accession |
Description |
Interval |
E-value |
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
94-467 |
9.00e-82 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 258.33 E-value: 9.00e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 94 RAALTSTGRSQLERIAGSRTPLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTA 173
Cdd:COG5002 5 LLLLLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 174 GIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAA----LSARQASETR 249
Cdd:COG5002 85 LLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAverdITELERLEQM 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 250 VRQFVADASHELRTPLAAIRGYTELTQR-IGDDPEAVAHAMSRVASETERITRLVEDLLLLARLDSGR-PLERGPVDMSR 327
Cdd:COG5002 165 RREFVANVSHELRTPLTSIRGYLELLLDgAADDPEERREYLEIILEEAERLSRLVNDLLDLSRLESGElKLEKEPVDLAE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 328 LAVDAVSDAHVAGPD--HQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPG 405
Cdd:COG5002 245 LLEEVVEELRPLAEEkgIELELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDDQVRISVRDTGIG 324
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 888550169 406 IPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPL 467
Cdd:COG5002 325 IPEEDLPRIFERFYRVDKSRSRETGGTGLGLAIVKHIVEAHGGRIWVESEPGKgTTFTITLPL 387
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
235-467 |
1.40e-71 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 226.71 E-value: 1.40e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 235 HIAAALSARQASETRVRQFVADASHELRTPLAAIRGYTE-LTQRIGDDPEAVAHAMSRVASETERITRLVEDLLLLARLD 313
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAElLLDEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 314 SGR-PLERGPVDMSRLAVDAVSDAHVAGP--DHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLST 390
Cdd:COG2205 81 SGKlSLELEPVDLAELLEEAVEELRPLAEekGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 888550169 391 GPTHVVLQVIDNGPGIPAALQSEVFERFARGDtsRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPG-YTEFAVRLPL 467
Cdd:COG2205 161 EGDGVRISVSDNGPGIPEEELERIFERFYRGD--NSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGgGTTFTVTLPL 236
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
153-467 |
9.08e-70 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 225.17 E-value: 9.08e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 153 LQMLIIFGIVTVIALVAATTAGIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRM 232
Cdd:COG0642 14 LLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 233 LDHIAAALSARQASETRvRQFVADASHELRTPLAAIRGYTELTQRigDDPEAVAHAMSRVASETERITRLVEDLLLLARL 312
Cdd:COG0642 94 LLLLALLLLLEEANEAK-SRFLANVSHELRTPLTAIRGYLELLLE--ELDEEQREYLETILRSADRLLRLINDLLDLSRL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 313 DSGR-PLERGPVDMSRLAVDAVSDAHVAGPDHQWAL--DLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLS 389
Cdd:COG0642 171 EAGKlELEPEPVDLAELLEEVVELFRPLAEEKGIELelDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVR 250
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 888550169 390 TGPTHVVLQVIDNGPGIPAALQSEVFERFARGDtsRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPG-YTEFAVRLPL 467
Cdd:COG0642 251 REGDRVRISVEDTGPGIPPEDLERIFEPFFRTD--PSRRGGGTGLGLAIVKRIVELHGGTIEVESEPGkGTTFTVTLPL 327
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
249-465 |
1.10e-54 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 185.87 E-value: 1.10e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 249 RVRQ-FVADASHELRTPLAAIRGYTE-LTQRIGDDPEAVAHAMSRVASETERITRLVEDLLLLARLDSGR-PLERGPVDM 325
Cdd:TIGR02966 112 QMRRdFVANVSHELRTPLTVLRGYLEtLADGPDEDPEEWNRALEIMLEQSQRMQSLVEDLLTLSRLESAAsPLEDEPVDM 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 326 SRLAVDAVSDAHV--AGPDHQWALDLPPePVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNG 403
Cdd:TIGR02966 192 PALLDHLRDEAEAlsQGKNHQITFEIDG-GVDVLGDEDELRSAFSNLVSNAIKYTPEGGTITVRWRRDGGGAEFSVTDTG 270
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 888550169 404 PGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRL 465
Cdd:TIGR02966 271 IGIAPEHLPRLTERFYRVDKSRSRDTGGTGLGLAIVKHVLSRHHARLEIESELGKgSTFSFIF 333
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
126-466 |
3.25e-48 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 172.19 E-value: 3.25e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 126 RVLAAPSRNG--HDVIVTGLSMGNVDATMLQML-IIFGIVTVIALVAATtAGIVIIKRALAPLRRVAQTASEVVDLPLDR 202
Cdd:TIGR01386 131 SVAALPGGKGrkPVQITVALDINAHTHLLDALRkWLILIAVLLVLLTAL-LGWWITRLGLEPLRRLSAVAARISPESLDQ 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 203 gevklpvRVPEPDAnpSTEVGQLGSALNRMLDHIAAALsarqaseTRVRQFVADASHELRTPLAAIRGYTE--LTQ-RIG 279
Cdd:TIGR01386 210 -------RLDPSRA--PAELRELAQSFNAMLGRLEDAF-------QRLSQFSADLAHELRTPLTNLLGQTQvaLSQpRTG 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 280 DDPEAVAHAMsrvASETERITRLVEDLLLLARLDSGR-PLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVViPG 358
Cdd:TIGR01386 274 EEYREVLESN---LEELERLSRMVSDMLFLARADNGQlALERVRLDLAAELAKVAEYFEPLAEERGVRIRVEGEGLV-RG 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 359 DAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAI 438
Cdd:TIGR01386 350 DPQMFRRAISNLLSNALRHTPDGGTITVRIERRSDEVRVSVSNPGPGIPPEHLSRLFDRFYRVDPARSNSGEGTGLGLAI 429
|
330 340
....*....|....*....|....*...
gi 888550169 439 VSAVVKAHNGTITVSSSPGYTEFAVRLP 466
Cdd:TIGR01386 430 VRSIMEAHGGRASAESPDGKTRFILRFP 457
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
117-467 |
5.71e-46 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 163.82 E-value: 5.71e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 117 LDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPLRRVAQTASEVV 196
Cdd:COG4191 3 RLLLLLLLLLALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 197 DLPLDRGEVKLPVRVPEPDAnpsTEVGQLGSALNRMLDHIAAALSARQASETRVRQ---------FVADASHELRTPLAA 267
Cdd:COG4191 83 GLLLLLLLEALLLLLLAALD---AEENAELEELERDITELERAEEELRELQEQLVQseklaalgeLAAGIAHEINNPLAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 268 IRGYTELTQRI---GDDPEAVAHAMSRVASETERITRLVEDLLLLARLDsgrPLERGPVDMSRLAVDAVS--DAHVAGPD 342
Cdd:COG4191 160 ILGNAELLRRRledEPDPEELREALERILEGAERAAEIVRSLRAFSRRD---EEEREPVDLNELIDEALEllRPRLKARG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 343 HQWALDLPPEPVVIPGDAARLHQVVTNLLANAR---VHTGPGTI-VTTRLSTGptHVVLQVIDNGPGIPAALQSEVFERF 418
Cdd:COG4191 237 IEVELDLPPDLPPVLGDPGQLEQVLLNLLINAIdamEEGEGGRItISTRREGD--YVVISVRDNGPGIPPEVLERIFEPF 314
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 888550169 419 ArgdTSRSRQAGsTGLGLAIVSAVVKAHNGTITVSSSPG-YTEFAVRLPL 467
Cdd:COG4191 315 F---TTKPVGKG-TGLGLSISYGIVEKHGGRIEVESEPGgGTTFTITLPL 360
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
258-467 |
6.61e-44 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 159.74 E-value: 6.61e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 258 SHELRTPLAAIRGYTELTQR-----IGDDPEAVAHAMSRVASETERITRLVEDLLLLARLdsgRPLERGPVDMSRL---A 329
Cdd:COG5000 209 AHEIKNPLTPIQLSAERLRRkladkLEEDREDLERALDTIIRQVDRLKRIVDEFLDFARL---PEPQLEPVDLNELlreV 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 330 VDAVSDAHvAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAA 409
Cdd:COG5000 286 LALYEPAL-KEKDIRLELDLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDGRVRIEVSDNGPGIPEE 364
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 888550169 410 LQSEVFERFArgdTSRSRqagSTGLGLAIVSAVVKAHNGTITVSSSPG-YTEFAVRLPL 467
Cdd:COG5000 365 VLERIFEPFF---TTKPK---GTGLGLAIVKKIVEEHGGTIELESRPGgGTTFTIRLPL 417
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
239-467 |
1.41e-43 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 157.32 E-value: 1.41e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 239 ALSARQASetrVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAmSRVASETERITRLVEDLLLLARldsGRPL 318
Cdd:COG3852 127 RRAEKLAA---VGELAAGLAHEIRNPLTGIRGAAQLLERELPDDELREYT-QLIIEEADRLNNLVDRLLSFSR---PRPP 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 319 ERGPVDMSRLAVDAVSDAHVAGPDH-QWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTG-PGTI-VTTRLSTGPT-- 393
Cdd:COG3852 200 EREPVNLHEVLERVLELLRAEAPKNiRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPeGGTItIRTRVERQVTlg 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 394 ------HVVLQVIDNGPGIPAALQSEVFERFArgdTSRsrqAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLP 466
Cdd:COG3852 280 glrprlYVRIEVIDNGPGIPEEILDRIFEPFF---TTK---EKGTGLGLAIVQKIVEQHGGTIEVESEPGKgTTFRIYLP 353
|
.
gi 888550169 467 L 467
Cdd:COG3852 354 L 354
|
|
| HK_WalK |
NF033092 |
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in ... |
251-467 |
3.11e-43 |
|
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in Staphylococcus aureus (sp|Q2G2U4.1|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.
Pssm-ID: 467964 [Multi-domain] Cd Length: 594 Bit Score: 161.07 E-value: 3.11e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 251 RQFVADASHELRTPLAAIRGYTE-LTQRIGDDPEaVAHAMSRVA-SETERITRLVEDLLLLARLDSGR-PLERGPVDMSR 327
Cdd:NF033092 373 REFVANVSHELRTPLTTMRSYLEaLADGAWKDPE-LAPRFLGVTqNETERMIRLVNDLLQLSRMDSKDyKLNKEWVNFNE 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 328 LaVDAVSDAH---VAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGP 404
Cdd:NF033092 452 F-FNYIIDRFemiLKNKNITFKREFPKRDLWVEIDTDKITQVLDNIISNAIKYSPEGGTITFRLLETHNRIIISISDQGL 530
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 888550169 405 GIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPL 467
Cdd:NF033092 531 GIPKKDLDKIFDRFYRVDKARSRKMGGTGLGLAIAKEVVEAHGGRIWAESEEGKgTTIYFTLPY 594
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
156-457 |
2.19e-42 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 156.54 E-value: 2.19e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 156 LIIFGIVTVIALVAAttagiVIIKRALAPLRRVAQTASEvvdlpldrGEvklPVRVPEPdanPSTEVGQLGSALNRMLDh 235
Cdd:PRK11100 189 ALLLGIALLIGAGVV-----WWLNRSIRRLTRYADAVTE--------GK---PVPLPKL---GSSELRELAQALESMRV- 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 236 iaaALSARQAsetrVRQFVADASHELRTPLAAIRGYTELTQRiGDDPEAVAHAMSRVASETERITRLVEDLLLLARLDSG 315
Cdd:PRK11100 249 ---KLEGKAY----VEQYVQTLTHELKSPLAAIRGAAELLQE-DPPPEDRARFTGNILTQSARLQQLIDRLLELARLEQR 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 316 RPLE-RGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTH 394
Cdd:PRK11100 321 QELEvLEPVALAALLEELVEAREAQAAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQ 400
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 888550169 395 VVLQVIDNGPGIPAALQSEVFERF---ARGDTSRSrqagSTGLGLAIVSAVVKAHNGTITVSSSPG 457
Cdd:PRK11100 401 VALSVEDQGPGIPDYALPRIFERFyslPRPANGRK----STGLGLAFVREVARLHGGEVTLRNRPE 462
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
125-457 |
1.08e-41 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 154.04 E-value: 1.08e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 125 YRVLAAPSRNGHDVIVTG--------LSMGNVDATMLQMLIIFGIVTVIAlvaattagIVIIKRALAPLRRVAQT---AS 193
Cdd:PRK10337 129 WRFVWLTSPDGKYRIVVGqeweyredMALAIVAGQLIPWLVALPIMLIIL--------MVLLGRELAPLKKLALAlrmRD 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 194 EVVDLPLDRGevklpvRVPepdanpsTEVGQLGSALNRMLDHIAAALsarqaseTRVRQFVADASHELRTPLAAIRGYTE 273
Cdd:PRK10337 201 PDSETPLNAT------GVP-------SEVRPLVEALNQLFARTHAMM-------VRERRFTSDAAHELRSPLAALKVQTE 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 274 LTQRIGDDPEAVAHAMSRVASETERITRLVEDLLLLARLDSGRPLER-GPVDMSRLAVDAVSD----AHVAGPDhqWALD 348
Cdd:PRK10337 261 VAQLSDDDPQARKKALLQLHAGIDRATRLVDQLLTLSRLDSLDNLQDvAEIPLEDLLQSAVMDiyhtAQQAGID--VRLT 338
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 349 LPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGpthvVLQVIDNGPGI-PAALQsEVFERFAR--GDTsr 425
Cdd:PRK10337 339 LNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNAR----NFTVRDNGPGVtPEALA-RIGERFYRppGQE-- 411
|
330 340 350
....*....|....*....|....*....|..
gi 888550169 426 srQAGStGLGLAIVSAVVKAHNGTITVSSSPG 457
Cdd:PRK10337 412 --ATGS-GLGLSIVRRIAKLHGMNVSFGNAPE 440
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
94-466 |
1.83e-41 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 154.56 E-value: 1.83e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 94 RAALTSTGRSQLERIAGSRTPLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTA 173
Cdd:COG4251 112 LLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLVLLLL 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 174 GIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAALSARQASETRVR-- 251
Cdd:COG4251 192 LLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEEELEer 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 252 ------------QFVADASHELRTPLAAIRGYTE-LTQRIGDD-PEAVAHAMSRVASETERITRLVEDLLLLARLDSgRP 317
Cdd:COG4251 272 taelersneeleQFAYVASHDLREPLRKISGFSQlLEEDYGDKlDEEGREYLERIRDAAERMQALIDDLLAYSRVGR-QE 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 318 LERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIpGDAARLHQVVTNLLANARVHTGPGT--IVTTRLSTGPTHV 395
Cdd:COG4251 351 LEFEPVDLNELLEEVLEDLEPRIEERGAEIEVGPLPTVR-GDPTLLRQVFQNLISNAIKYSRPGEppRIEIGAEREGGEW 429
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 888550169 396 VLQVIDNGPGIPAALQSEVFERFARGDTSRSRQagSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLP 466
Cdd:COG4251 430 VFSVRDNGIGIDPEYAEKIFEIFQRLHSRDEYE--GTGIGLAIVKKIVERHGGRIWVESEPGEgATFYFTLP 499
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
218-478 |
5.20e-39 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 146.67 E-value: 5.20e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 218 PSTEVGQLGSALNRMLDHIAAALSARqasetrvRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAvahAMSRvasETE 297
Cdd:PRK10604 187 EGSSLERLGVAFNQMADNINALIASK-------KQLIDGIAHELRTPLVRLRYRLEMSDNLSAAESQ---ALNR---DIG 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 298 RITRLVEDLLLLARLDsgRP---LERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANA 374
Cdd:PRK10604 254 QLEALIEELLTYARLD--RPqneLHLSEPDLPAWLSTHLADIQAVTPEKTVRLDTPHQGDYGALDMRLMERVLDNLLNNA 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 375 RVHTGpgTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSS 454
Cdd:PRK10604 332 LRYAH--SRVRVSLLLDGNQACLIVEDDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIALAMGGSVNCDE 409
|
250 260
....*....|....*....|....*
gi 888550169 455 SP-GYTEFAVRLPLdgWQPLESSPR 478
Cdd:PRK10604 410 SElGGARFSFSWPV--WHNLPQFTS 432
|
|
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
53-477 |
8.33e-38 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 144.40 E-value: 8.33e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 53 YIRSGPGPRFLDAPGQPAGMVAAVVSD-------GTTVAAGYLTGsgsrAALTSTGRSQLERIAGSRTPLtldlDGLGRY 125
Cdd:NF040691 97 LLVPGDDPSGLGPRASGSVGLVSQIPEelreavaGGQVAQQYQSV----ALPSGDGSSAPALVVGTPVTL----PVAGNY 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 126 RVLaapsrnghdvivTGLSMGNVDAT--MLQMLIIFGIVTVIALVAATTAgiVIIKRALAPLRRVAQTASEVVDLPLDrg 203
Cdd:NF040691 169 ELY------------LLFPLEDEQSTlaLVRGTLLLGGLALVVLLGLIAW--LVTRQVVAPVRSAARTAERFAAGDLS-- 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 204 evklpVRVPEpdaNPSTEVGQLGSALNRMldhiAAALSaRQASE----TRV-RQFVADASHELRTPLAAIRGYTEL--TQ 276
Cdd:NF040691 233 -----ERMPV---KGEDDLARLARSFNQM----ADSLQ-RQIRQleelSRLqQRFVSDVSHELRTPLTTIRMAADVihDS 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 277 RIGDDPeAVAHAMSRVASETERITRLVEDLLLLARLDSGRP-LERGPVDMSRLAVDAVSDA-HVA-GPDHQWALDLPPEP 353
Cdd:NF040691 300 RDDFDP-ATARSAELLHTELDRFESLLSDLLEISRFDAGAAeLDVEPVDLRPLVRRVVDALrQLAeRAGVELRVDAPGTP 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 354 VVIPGDAARLHQVVTNLLANARVHtGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTG 433
Cdd:NF040691 379 VVAEVDPRRVERVLRNLVVNAIEH-GEGKPVVVTVAQDDTAVAVTVRDHGVGLKPGEVALVFDRFWRADPARARTTGGTG 457
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 888550169 434 LGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPLDGWQPLESSP 477
Cdd:NF040691 458 LGLAIALEDARLHGGWLEAWGRPGQgSQFRLTLPRVAGDRLTTSP 502
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
157-468 |
1.21e-37 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 143.23 E-value: 1.21e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 157 IIFGIVTVIALVAAttagiVIIKRA-LAPLRR-VAQTASevvdlpLDRGEvkLPVRVpepDANPSTEVGQLGSALNRMld 234
Cdd:PRK10549 168 LIVALSTLLAALAT-----FLLARGlLAPVKRlVEGTHK------LAAGD--FTTRV---TPTSRDELGRLAQDFNQL-- 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 235 hiAAALSARQASEtrvRQFVADASHELRTPLAAIRGYTELTQrigD-----DPEAVAHAMSRVASeterITRLVEDLLLL 309
Cdd:PRK10549 230 --ASTLEKNEQMR---RDFMADISHELRTPLAVLRGELEAIQ---DgvrkfTPESVASLQAEVGT----LTKLVDDLHQL 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 310 ARLDSGRPLER-GPVDMSRLAVDAVSDAHVAGPDHQWALDLP-PEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTR 387
Cdd:PRK10549 298 SLSDEGALAYRkTPVDLVPLLEVAGGAFRERFASRGLTLQLSlPDSATVFGDPDRLMQLFNNLLENSLRYTDSGGSLHIS 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 388 LSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSP-GYTEFAVRLP 466
Cdd:PRK10549 378 AEQRDKTLRLTFADSAPGVSDEQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPfGGVSITVELP 457
|
..
gi 888550169 467 LD 468
Cdd:PRK10549 458 LE 459
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
358-467 |
9.59e-35 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 125.45 E-value: 9.59e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 358 GDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDtSRSRQAGSTGLGLA 437
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTD-KRSRKIGGTGLGLS 79
|
90 100 110
....*....|....*....|....*....|.
gi 888550169 438 IVSAVVKAHNGTITVSSSPG-YTEFAVRLPL 467
Cdd:smart00387 80 IVKKLVELHGGEISVESEPGgGTTFTITLPL 110
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
156-456 |
1.46e-33 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 131.87 E-value: 1.46e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 156 LIIFGIVTVIALVAAttagiVIIKRAL-APLRRVAQTASEvvdlpLDRGEVKLPVRVPEPDanpstEVGQLGSALNRMld 234
Cdd:NF012163 167 WLIVALALLLAALAA-----FLLARGLlAPVKRLVEATHR-----LAAGDYTTRVTPTSND-----ELGKLAQDFNQL-- 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 235 hiAAALSARQASEtrvRQFVADASHELRTPLAAIRGYTELTQrigD-----DPEAVAHAMSRVASeterITRLVEDLLLL 309
Cdd:NF012163 230 --ASTLEKNEQMR---RDFMADISHELRTPLAVLRAELEAIQ---DgirkfTPESLDSLQAEVGT----LTKLVDDLHDL 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 310 ARLDSGR-PLERGPVDMSRLAVDAVSDAHVAGPDHQWAL--DLPPEPVVIpGDAARLHQVVTNLLANARVHTGPGTIVTT 386
Cdd:NF012163 298 SMSDEGAlAYQKASVDLVPLLEVEGGAFRERFASAGLELevSLPDSSLVF-GDRDRLMQLFNNLLENSLRYTDSGGSLHI 376
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 387 RLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSP 456
Cdd:NF012163 377 SASQRPKEVTLTVADSAPGVSDEQLARLFERFYRVEVSRNRASGGSGLGLAISLNIVQAHGGTLHAAHSP 446
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
112-466 |
1.88e-33 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 131.82 E-value: 1.88e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 112 RTPLTLDLDGLGRYRVLAAPSRNGH---------DVIVTglsmgnvdATMLQMLIIFgivtvIALVAattagiviIKRAL 182
Cdd:PRK09835 152 ALPVGPLVDGKPIYTLLIALSIDFHlhyindlknKLIMT--------ASVISLLIVF-----IVLLA--------VHKGH 210
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 183 APLRRVAQTASEVVDLPLDrgevklpVRVpEPDANPsTEVGQLGSALNRMLDHIAAALSaRQASetrvrqFVADASHELR 262
Cdd:PRK09835 211 APIRSVSRQIQNITSKDLD-------VRL-DPQTVP-IELEQLVLSFNHMIERIEDVFT-RQSN------FSADIAHEIR 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 263 TPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLVEDLLLLARLDSGR-PLERGPVDMSRlAVDAVSDAHVA-G 340
Cdd:PRK09835 275 TPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQlIPEKKMLDLAD-EVGKVFDFFEAwA 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 341 PDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFAR 420
Cdd:PRK09835 354 EERGVELRFVGDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVENPGTPIAPEHLPRLFDRFYR 433
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 888550169 421 GDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 466
Cdd:PRK09835 434 VDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTSDARGTRFVISLP 479
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
241-467 |
1.58e-32 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 128.71 E-value: 1.58e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 241 SARQASETR----VRQFVADASHELRTPLAAIRGYTELtQRIGDDPEAVAHAMSRVASETERITRLVEDLLLLarldsGR 316
Cdd:COG5808 228 RVIQEINTQklelIGTFAASTAHEIRNPLTSIKGFIQL-LQEKYPELEDQKYFDIIQEEIQRINQIVSEFLVL-----GK 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 317 P--LERGPVDMSRLAVDAVS--DAHVAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGP 392
Cdd:COG5808 302 PtaKKLELDDLNELIEEILSiiDSEANLKNIRVEKQSLDEPLHIKCDKDRIKQVLLNLIKNAIEAMKEGGKLTISIENDD 381
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 888550169 393 THVVLQVIDNGPGIPAALQSEVFERFArgdTSRSrqaGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPL 467
Cdd:COG5808 382 EKAVIEVIDNGEGIPEDIIDEIFEPFV---TTKE---GGTGLGLSVCKRIVEMHGGEIDIESEEGKgTTFTIRLPL 451
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
363-465 |
1.60e-32 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 119.24 E-value: 1.60e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRqaGSTGLGLAIVSAV 442
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSREG--GGTGLGLAIVRRI 78
|
90 100
....*....|....*....|....
gi 888550169 443 VKAHNGTITVSSSPG-YTEFAVRL 465
Cdd:cd00075 79 VEAHGGRITVESEPGgGTTFTVTL 102
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
251-466 |
1.37e-31 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 125.89 E-value: 1.37e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 251 RQFVADASHELRTPLAAIRGYTELTQrigdDPEAVA----HAMSRVASETERITRLVEDLLLLARLDSGRPLERG----- 321
Cdd:PRK11006 205 RNFFANVSHELRTPLTVLQGYLEMMQ----DQPLEGalreKALHTMREQTQRMEGLVKQLLTLSKIEAAPTIDLNekvdv 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 322 PVDMSRLAVDAVSdahVAGPDHQWALDLPPEPVVIpGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVID 401
Cdd:PRK11006 281 PMMLRVLEREAQT---LSQGKHTITFEVDNSLKVF-GNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQGAEFSVED 356
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 888550169 402 NGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLP 466
Cdd:PRK11006 357 NGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALSHHDSRLEIESEVGKgTRFSFVLP 422
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
180-469 |
8.56e-31 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 123.89 E-value: 8.56e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 180 RALA-PLRRVAQTASEVVdlpldRGEVKLpvrvpepdaNPSTEVG-----QLGSALNRMLDHIAAALSARQAsetrvrqF 253
Cdd:PRK09470 188 WSLAkPARKLKNAADEVA-----QGNLRQ---------HPELETGpqefrQAGASFNQMVTALERMMTSQQR-------L 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 254 VADASHELRTPLAAIRGYTEL-TQRIGDDPEavahaMSRVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRLAVDA 332
Cdd:PRK09470 247 LSDISHELRTPLTRLQLATALlRRRQGESKE-----LERIETEAQRLDSMINDLLVLSRNQQKNHLERETFKANSLWSEV 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 333 VSDAHVAGpdHQWALDL----PPEPVVIPGDAARLHQVVTNLLANARVHTGpgTIVTTRLSTGPTHVVLQVIDNGPGIPA 408
Cdd:PRK09470 322 LEDAKFEA--EQMGKSLtvsaPPGPWPINGNPNALASALENIVRNALRYSH--TKIEVAFSVDKDGLTITVDDDGPGVPE 397
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 888550169 409 ALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSP-GYTEFAVRLPLDG 469
Cdd:PRK09470 398 EEREQIFRPFYRVDEARDRESGGTGLGLAIVENAIQQHRGWVKAEDSPlGGLRLTIWLPLYK 459
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
240-468 |
9.66e-31 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 125.47 E-value: 9.66e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 240 LSARQASETRVRQ---------FVADASHELRTPLAAIRGYTELTQRIGDDPEAvAHAMSRVASETERITRLVEDLLLLA 310
Cdd:PRK11360 371 LTERKRLQRRVARqerlaalgeLVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPS-QEYLSVVLREVDRLNKVIDQLLEFS 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 311 RldsGRPLERGPVDMSRLAVDA---VSDAHV-AGPDHQWALD--LPPepvvIPGDAARLHQVVTNLLANA-RVHTGPGTI 383
Cdd:PRK11360 450 R---PRESQWQPVSLNALVEEVlqlFQTAGVqARVDFETELDneLPP----IWADPELLKQVLLNILINAvQAISARGKI 522
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 384 -VTTRLsTGPTHVVLQVIDNGPGIPAALQSEVFERFARgdtsrSRQAGsTGLGLAIVSAVVKAHNGTITVSSSPGY-TEF 461
Cdd:PRK11360 523 rIRTWQ-YSDGQVAVSIEDNGCGIDPELLKKIFDPFFT-----TKAKG-TGLGLALSQRIINAHGGDIEVESEPGVgTTF 595
|
....*..
gi 888550169 462 AVRLPLD 468
Cdd:PRK11360 596 TLYLPIN 602
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
211-468 |
2.25e-29 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 122.07 E-value: 2.25e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 211 VPEPDANPSTEVGQLGSALNRMldHIAA-ALSARQASET-RVRQ-FVADASHELRTPLAAIRGYTE-LTQRIGDDPEAVA 286
Cdd:PRK10490 624 IPEQQRLLETFTLLIANALERL--TLTAsEEQARLASEReQLRNaLLAALSHDLRTPLTVLFGQAEiLTLDLASEGSPHA 701
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 287 HAMSRVASETERITRLVEDLLLLARLDS-GRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQ 365
Cdd:PRK10490 702 RQASEIRQQVLNTTRLVNNLLDMARIQSgGFNLRKEWLTLEEVVGSALQMLEPGLSGHPINLSLPEPLTLIHVDGPLFER 781
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 366 VVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDtSRSRQAGsTGLGLAIVSAVVKA 445
Cdd:PRK10490 782 VLINLLENAVKYAGAQAEIGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKFARGN-KESAIPG-VGLGLAICRAIVEV 859
|
250 260
....*....|....*....|....
gi 888550169 446 HNGTITVSSSP-GYTEFAVRLPLD 468
Cdd:PRK10490 860 HGGTIWAENRPeGGACFRVTLPLE 883
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
250-468 |
7.01e-29 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 116.81 E-value: 7.01e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 250 VRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHaMSRVASETERITRLVEDLLLLARLDSgrplergpVDMSRLA 329
Cdd:COG5807 147 AGELAAGIAHEIRNPLTSIKGFLQLLQESREDSEREEY-FNIIISEIDRINTIITELLVLSKPKK--------FNFKKLN 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 330 VDAVSDAHVAGPDHQWAL-------DLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDN 402
Cdd:COG5807 218 LNDVLEDVIALLSTEAILknisikyDLADDEPVINGDKNQLKQVFINLIKNAIEAMETGGNITIKTYVEGDFVVISVKDE 297
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 888550169 403 GPGIPAALQSEVFERFArgdTSRSRqagSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPLD 468
Cdd:COG5807 298 GIGIPEEVLEKIGEPFF---TTKEE---GTGLGLSICKKIIEEHNGTIEVESKPGKgTTFTIYLPLY 358
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
358-468 |
2.03e-28 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 108.61 E-value: 2.03e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 358 GDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGpTHVVLQVIDNGPGIPAALQSEVFERFARGDtsrSRQAGSTGLGLA 437
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSEG-GELTLTVEDNGIGIPPEDLPRIFEPFSTAD---KRGGGGTGLGLS 76
|
90 100 110
....*....|....*....|....*....|..
gi 888550169 438 IVSAVVKAHNGTITVSSSPGY-TEFAVRLPLD 468
Cdd:pfam02518 77 IVRKLVELLGGTITVESEPGGgTTVTLTLPLA 108
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
199-456 |
6.83e-28 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 113.91 E-value: 6.83e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 199 PLDRGEVKLPVRVPE-----PDANPSTEVGQLGSALNRMLDHIAAALSarqasetRVRQFVADASHELRTPLAAIRGYTE 273
Cdd:PRK10755 88 PLAELQKELEARTADnltpiAIHSSTLEIEAVTSALNQLVSRLTSTLD-------QERLFTADVAHELRTPLAGIRLHLE 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 274 LTQRIGddPEAVAHAMSRVasetERITRLVEDLLLLARLdsGRPLERGPVDMSRLAVDAVS------DAHVAGPDHQWAL 347
Cdd:PRK10755 161 LLEKQH--HIDVAPLIARL----DQMMHTVEQLLQLARA--GQSFSSGHYQTVKLLEDVILpsqdelSEMLEQRQQTLLL 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 348 DLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDtsrSR 427
Cdd:PRK10755 233 PESAADITVQGDATLLRLLLRNLVENAHRYSPEGSTITIKLSQEDGGAVLAVEDEGPGIDESKCGELSKAFVRMD---SR 309
|
250 260
....*....|....*....|....*....
gi 888550169 428 QAGStGLGLAIVSAVVKAHNGTITVSSSP 456
Cdd:PRK10755 310 YGGI-GLGLSIVSRITQLHHGQFFLQNRQ 337
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
141-467 |
2.01e-27 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 113.85 E-value: 2.01e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 141 TGLSMGNVDATMLQMLIIfGIVTVIAlvaattaGIVIIKRALAPLRRVAQTASEVvdlplDRGEVKLPVRvpepdANPST 220
Cdd:PRK09467 145 TEIHQGDFSPLFRYTLAI-GLLSVAG-------GWLFIRIQNRPLVALEHAALQV-----GKGEIPPPLR-----EYGAS 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 221 EVGQLGSALNRMldhiaaALSARQASETRvRQFVADASHELRTPLAAIRGYTELtqrIGDDPEAVAHAMSrvaSETERIT 300
Cdd:PRK09467 207 EVRSVTRAFNQM------AAGIKQLEDDR-TLLMAGVSHDLRTPLTRIRLATEM---MSEEDGYLAESIN---KDIEECN 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 301 RLVEDLLLLARLDSGRPLErgPVDMSRLAVDAVSDAHvaGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANArVHTGP 380
Cdd:PRK09467 274 AIIEQFIDYLRTGQEMPME--MADLNALLGEVIAAES--GYEREIETALQPGPIEVPMNPIAIKRALANLVVNA-ARYGN 348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 381 GTIvttRLSTGPTH--VVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAgsTGLGLAIVSAVVKAHNGTITVSSSP-G 457
Cdd:PRK09467 349 GWI---KVSSGTEGkrAWFQVEDDGPGIPPEQLKHLFQPFTRGDSARGSSG--TGLGLAIVKRIVDQHNGKVELGNSEeG 423
|
330
....*....|
gi 888550169 458 YTEFAVRLPL 467
Cdd:PRK09467 424 GLSARAWLPL 433
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
359-466 |
8.77e-27 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 104.11 E-value: 8.77e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 359 DAARLHQVVTNLLANARVHTGPGTIVTTRLS-TGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLA 437
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRIRCILEkFRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGGTGLGLS 80
|
90 100 110
....*....|....*....|....*....|
gi 888550169 438 IVSAVVKAHNGTITVSSSPGY-TEFAVRLP 466
Cdd:cd16925 81 IVKEFVELHGGTVTVSDAPGGgALFQVELP 110
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
248-468 |
4.20e-26 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 110.83 E-value: 4.20e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 248 TRVRQFVADASHELRTPLAAIRGYTELTQ-RIGDDPEAVAHAMSrvaSETERITRLVEDLLLLARLDSGRPlerGPVDMS 326
Cdd:COG5809 268 SVVGELAAGIAHEIRNPLTSLKGFIQLLKdTIDEEQKTYLDIML---SELDRIESIISEFLVLAKPQAIKY---EPKDLN 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 327 RLAVDAV----SDAHVAGPDHQWAL--DLPPepvvIPGDAARLHQVVTNLLANA-RVHTGPGTIVTTRLSTGPTHVVLQV 399
Cdd:COG5809 342 TLIEEVIpllqPQALLKNVQIELELedDIPD----ILGDENQLKQVFINLLKNAiEAMPEGGNITIETKAEDDDKVVISV 417
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 400 IDNGPGIPAALQSEVFERFArgdtsrSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPLD 468
Cdd:COG5809 418 TDEGCGIPEERLKKLGEPFY------TTKEKGTGLGLMVSYKIIEEHGGKITVESEVGKgTTFSITLPIK 481
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
363-467 |
4.12e-25 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 99.49 E-value: 4.12e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANARVHTGPGTIVTT--RLSTGPTHVVL--QVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAI 438
Cdd:cd16922 1 LRQILLNLLGNAIKFTEEGEVTLRvsLEEEEEDGVQLrfSVEDTGIGIPEEQQARLFEPFSQADSSTTRKYGGTGLGLAI 80
|
90 100 110
....*....|....*....|....*....|
gi 888550169 439 VSAVVKAHNGTITVSSSPGY-TEFAVRLPL 467
Cdd:cd16922 81 SKKLVELMGGDISVESEPGQgSTFTFTLPL 110
|
|
| TMAO_torS |
TIGR02956 |
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the ... |
221-476 |
3.69e-24 |
|
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems]
Pssm-ID: 274362 [Multi-domain] Cd Length: 968 Bit Score: 106.40 E-value: 3.69e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 221 EVGQLGSALN-RMLDHIAAALSARQASETRvRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAvAHAMSRVASETERI 299
Cdd:TIGR02956 435 ELAETNERLNaEVKNHAKARAEAEEANRAK-SAFLATMSHEIRTPLNGILGTLELLGDTGLTSQQ-QQYLQVINRSGESL 512
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 300 TRLVEDLLLLARLDSGR-PLERGPVDMSRLAVDAV----SDAHVAGPdhQWALDLPPE-PVVIPGDAARLHQVVTNLLAN 373
Cdd:TIGR02956 513 LDILNDILDYSKIEAGHlSISPRPFDLNALLDDVHhlmvSRAQLKGI--QLRLNIPEQlPNWWQGDGPRIRQVLINLVGN 590
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 374 ARVHTGPGTiVTTRLSTGP-THVVLQVIDNGPGIPAALQSEVFERFARGDTSRSrqAGSTGLGLAIVSAVVKAHNGTITV 452
Cdd:TIGR02956 591 AIKFTDRGS-VVLRVSLNDdSSLLFEVEDTGCGIAEEEQATLFDAFTQADGRRR--SGGTGLGLAISQRLVEAMDGELGV 667
|
250 260
....*....|....*....|....*
gi 888550169 453 SSSPGY-TEFAVRLPLDGWQPLESS 476
Cdd:TIGR02956 668 ESELGVgSCFWFTLPLTRGKPAEDS 692
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-466 |
4.06e-23 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 93.68 E-value: 4.06e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 359 DAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAI 438
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGGSGLGLAI 80
|
90 100
....*....|....*....|....*....
gi 888550169 439 VSAVVKAHNGTITVSSSP-GYTEFAVRLP 466
Cdd:cd16946 81 CHNIALAHGGTISAEHSPlGGLRLVLTLP 109
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
218-475 |
5.49e-22 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 99.37 E-value: 5.49e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 218 PSTEVGQLGSALNRMLDHI--------AAALSARQASETR---VRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVA 286
Cdd:PRK13837 407 PAGELQLLELALDCLAHAIerrrleteRDALERRLEHARRleaVGTLASGIAHNFNNILGAILGYAEMALNKLARHSRAA 486
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 287 HAMSRVASETERITRLVEDLLLLARLdsgRPLERGPVDMSRLAVDAVSDAHVAGPDH-QWALDLPPEPVVIPGDAARLHQ 365
Cdd:PRK13837 487 RYIDEIISAGARARLIIDQILAFGRK---GERNTKPFDLSELVTEIAPLLRVSLPPGvELDFDQDQEPAVVEGNPAELQQ 563
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 366 VVTNLLANARVHTGPGTIVTTRLS----TGPT-----------HVVLQVIDNGPGIPAALQSEVFERFArgdTSRsrqAG 430
Cdd:PRK13837 564 VLMNLCSNAAQAMDGAGRVDISLSraklRAPKvlshgvlppgrYVLLRVSDTGAGIDEAVLPHIFEPFF---TTR---AG 637
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 888550169 431 STGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPLDGWQPLES 475
Cdd:PRK13837 638 GTGLGLATVHGIVSAHAGYIDVQSTVGRgTRFDVYLPPSSKVPVAP 683
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
160-469 |
3.03e-21 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 95.30 E-value: 3.03e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 160 GIVTVIALVAATTAGIVIIKRALAPLRRvaqtasEVVDLPLDRGEVKLPVRVPEPDANPSTEVGQLGSALNRMLDHIAAA 239
Cdd:COG3290 104 GRITLINDAARRLLGLDAIGRPIDEVLA------EVLETGERDEEILLNGRVLVVNRVPIRDDGRVVGAVATFRDRTELE 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 240 LSARQASETRVrqfVADA----SHELRTPLAAIRGYTELtqriGDDPEAVAHAM---SRVASETERITRLVEDL----LL 308
Cdd:COG3290 178 RLEEELEGVKE---LAEAlraqRHDFRNHLHTISGLLQL----GEYDEALEYIDeisEELQELIDSLLSRIGNPvlaaLL 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 309 LARLDSGRplERGPvdmsRLAVDAVSDahvagpdhqwaldLPPEPVvipgDAARLHQVVTNLLANA----RVHTGPGTIV 384
Cdd:COG3290 251 LGKAARAR--ERGI----DLTIDIDSD-------------LPDLPL----SDTDLVTILGNLLDNAieavEKLPEEERRV 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 385 TTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERfarGDTSRSrqAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAV 463
Cdd:COG3290 308 ELSIRDDGDELVIEVEDSGPGIPEELLEKIFER---GFSTKL--GEGRGLGLALVKQIVEKYGGTIEVESEEGEgTVFTV 382
|
....*.
gi 888550169 464 RLPLDG 469
Cdd:COG3290 383 RLPKEG 388
|
|
| marine_sort_HK |
TIGR03785 |
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is ... |
185-466 |
1.06e-20 |
|
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is paired with an adjacent response regulator (TIGR03787) gene. It co-occurs with a variant sortase enzyme (TIGR03784), usually in the same gene neighborhood, in proteobacterial species most of which are marine, and with an LPXTG motif-containing sortase target conserved protein (TIGR03788). Sortases and LPXTG proteins are far more common in Gram-positive bacteria, where sortase systems mediate attachment to the cell wall or cross-linking of pilin structures. We give this predicted sensor histidine kinase the gene symbol psdS, for Proteobacterial Dedicated Sortase system Sensor histidine kinase.
Pssm-ID: 163497 [Multi-domain] Cd Length: 703 Bit Score: 95.20 E-value: 1.06e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 185 LRRVAQTASEVVDlplDRGevKLPVRVPEPDANpsTEVGQLGSALNRMLdhiaaalsARQASETR-VRQFVADASHELRT 263
Cdd:TIGR03785 434 IRRLSDDAEAAID---SQG--RISGAIPASRSR--DEIGDLSRSFAQMV--------ARLRQYTHyLENMSSRLSHELRT 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 264 PLAAIRGYTELTQRIGDDPEAVAHAmSRVASETERITRLVEDLLLLARLD-SGRPLERGPVDMSRLAVDAVSDAHVAGPD 342
Cdd:TIGR03785 499 PVAVVRSSLENLELQALEQEKQKYL-ERAREGTERLSMILNNMSEATRLEqAIQSAEVEDFDLSEVLSGCMQGYQMTYPP 577
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 343 HQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGD 422
Cdd:TIGR03785 578 QRFELNIPETPLVMRGSPELIAQMLDKLVDNAREFSPEDGLIEVGLSQNKSHALLTVSNEGPPLPEDMGEQLFDSMVSVR 657
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 888550169 423 TSRSRQAGSTGLGLAIVSAVVKAHNGTITV---SSSPGYTeFAVRLP 466
Cdd:TIGR03785 658 DQGAQDQPHLGLGLYIVRLIADFHQGRIQAenrQQNDGVV-FRISLP 703
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
252-468 |
3.19e-20 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 94.42 E-value: 3.19e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 252 QFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLVEDLLLLARLDSGR-PLERGPVDMSRLAV 330
Cdd:PRK09959 714 QFLATMSHEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNyQLQPQWVDIPTLVQ 793
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 331 DAVSDAHVAGPDHQWALDLP---PEPVVIPGDAARLHQVVTNLLANARVHTGPGT--IVTTRLSTGPTHVVLQ--VIDNG 403
Cdd:PRK09959 794 NTCHSFGAIAASKSIALSCSstfPDHYLVKIDPQAFKQVLSNLLSNALKFTTEGAvkITTSLGHIDDNHAVIKmtIMDSG 873
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 888550169 404 PGIPAALQSEVFERFARgdTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPLD 468
Cdd:PRK09959 874 SGLSQEEQQQLFKRYSQ--TSAGRQQTGSGLGLMICKELIKNMQGDLSLESHPGIgTTFTITIPVE 937
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
119-474 |
4.51e-20 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 93.55 E-value: 4.51e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 119 LDGLGRYRVLAAPSRNGHDVIvtglsmgnvdatmLQMLIIFGIVTVIALVAATTAGIVIIKRALA-PLRRVAQTASEVVD 197
Cdd:PRK15347 271 LKGPGWQQVTLYPRRNLANEA-------------LKPALQQLPFALLILVLLTSVLFLLLRRYLAkPLWRFVDIINKTGP 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 198 LPLDRgevklpvRVPEpdaNPSTEVGQLGSALNRMLDHIAA--------------ALS-ARQASE---TRVRQFVADASH 259
Cdd:PRK15347 338 AALEP-------RLPE---NRLDELGSIAKAYNQLLDTLNEqydtlenkvaertqALAeAKQRAEqanKRKSEHLTTISH 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 260 ELRTPLAAIRGYTELTQRIGDDPEAVahamsRVASETERITR----LVEDLLLLARLDSGRpLErgpVDMSRLAVDAVSD 335
Cdd:PRK15347 408 EIRTPLNGVLGALELLQNTPLTAEQM-----DLADTARQCTLsllaIINNLLDFSRIESGQ-MT---LSLEETALLPLLD 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 336 ---AHVAGPDHQWALDL-----PPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGpTHVVLQVIDNGPGIP 407
Cdd:PRK15347 479 qamLTIQGPAQSKSLTLrtfvgAHVPLYLHLDSLRLRQILVNLLGNAVKFTETGGIRLRVKRHE-QQLCFTVEDTGCGID 557
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 888550169 408 AALQSEVFERFARGDTsrsrQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPLDGWQPLE 474
Cdd:PRK15347 558 IQQQQQIFTPFYQADT----HSQGTGLGLTIASSLAKMMGGELTLFSTPGVgSCFSLVLPLNEYAPPE 621
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
232-467 |
8.89e-20 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 92.66 E-value: 8.89e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 232 MLDHIAAALSARQASETRvRQFVADASHELRTPLAAIRGYTELtqrIGDDPEAVAHA--MSRVASETERITRLVEDLLLL 309
Cdd:PRK11466 427 VIEHRQARAEAEKASQAK-SAFLAAMSHEIRTPLYGILGTAQL---LADNPALNAQRddLRAITDSGESLLTILNDILDY 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 310 ARLDSG--------RPLERGPVDMS--RLAVDAVSDAHVAgPDHQWALDLPpepVVIPGDAARLHQVVTNLLANARVHTG 379
Cdd:PRK11466 503 SAIEAGgknvsvsdEPFEPRPLLEStlQLMSGRVKGRPIR-LATDIADDLP---TALMGDPRRIRQVITNLLSNALRFTD 578
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 380 PGTIVTtRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRsrqaGSTGLGLAIVSAVVKAHNGTITVSSSPGY- 458
Cdd:PRK11466 579 EGSIVL-RSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKR----GGTGLGLTISSRLAQAMGGELSATSTPEVg 653
|
....*....
gi 888550169 459 TEFAVRLPL 467
Cdd:PRK11466 654 SCFCLRLPL 662
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
352-457 |
2.05e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 83.61 E-value: 2.05e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 352 EPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLStGPTHVVLQVIDNGPGIPAALQSEVFERFARGDtsrSRQAGS 431
Cdd:cd16940 3 ADIQVQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKLS-ADDGAVIRVEDNGPGIDEEELEALFERFYRSD---GQNYGG 78
|
90 100
....*....|....*....|....*.
gi 888550169 432 TGLGLAIVSAVVKAHNGTITVSSSPG 457
Cdd:cd16940 79 SGLGLSIVKRIVELHGGQIFLGNAQG 104
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-466 |
2.15e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 83.22 E-value: 2.15e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANAR---VHTGPGTIVTTRLSTGPT------HVVLQ--VIDNGPGIPAALQSEVFERFARGdtsrsrQAGS 431
Cdd:cd16918 1 LIQVFLNLVRNAAqalAGSGGEIILRTRTQRQVTlghprhRLALRvsVIDNGPGIPPDLQDTIFYPMVSG------RENG 74
|
90 100 110
....*....|....*....|....*....|....*
gi 888550169 432 TGLGLAIVSAVVKAHNGTITVSSSPGYTEFAVRLP 466
Cdd:cd16918 75 TGLGLAIAQNIVSQHGGVIECDSQPGHTVFSVSLP 109
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
227-467 |
3.22e-19 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 90.80 E-value: 3.22e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 227 SALNRM---LDHIAAAlsARQASETRvRQFVADASHELRTPLAAIRGYTEL--TQRIGDDPEAVAHAMSRVASETERItr 301
Cdd:PRK10841 424 SARVKMeesLQEMAQA--AEQASQSK-SMFLATVSHELRTPLYGIIGNLDLlqTKELPKGVDRLVTAMNNSSSLLLKI-- 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 302 lVEDLLLLARLDSgrplERGPVDMSRLAVDAVSdAHVAGPdhqwALDL-------------PPEPVVIPGDAARLHQVVT 368
Cdd:PRK10841 499 -ISDILDFSKIES----EQLKIEPREFSPREVI-NHITAN----YLPLvvkkrlglycfiePDVPVALNGDPMRLQQVIS 568
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 369 NLLANARVHTGPGTIVTTRLSTGpTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNG 448
Cdd:PRK10841 569 NLLSNAIKFTDTGCIVLHVRVDG-DYLSFRVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLINMMDG 647
|
250 260
....*....|....*....|
gi 888550169 449 TITVSSSPGY-TEFAVRLPL 467
Cdd:PRK10841 648 DISVDSEPGMgSQFTIRIPL 667
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
252-467 |
3.32e-19 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 90.18 E-value: 3.32e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 252 QFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMsrvASETERITRLVEDLLLLARLDSgrpLERGPVDMSRLAVD 331
Cdd:COG5805 289 QLAAGIAHEIRNPLTSIKGFLQLLQPGIEDKEEYFDIM---LSELDRIESIISEFLALAKPQA---VNKEKENINELIQD 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 332 AVS----DAHVAgpDHQWALDLPPEPVVIPGDAARLHQVVTNLLANArVHTGP-GTIVTTRLSTGPTHVVLQVIDNGPGI 406
Cdd:COG5805 363 VVTlletEAILH--NIQIRLELLDEDPFIYCDENQIKQVFINLIKNA-IEAMPnGGTITIHTEEEDNSVIIRVIDEGIGI 439
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 888550169 407 PAALQSEVFERFARgdtsrSRQAGsTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPL 467
Cdd:COG5805 440 PEERLKKLGEPFFT-----TKEKG-TGLGLMVSYKIIENHNGTIDIDSKVGKgTTFTITLPL 495
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
242-468 |
6.76e-19 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 89.91 E-value: 6.76e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 242 ARQASetRVR-QFVADASHELRTPLAAIRGYTEL--------TQRigdDpeaVAHAMSRVASETERItrlVEDLLLLARL 312
Cdd:PRK11107 286 AQEAA--RIKsEFLANMSHELRTPLNGVIGFTRQtlktpltpTQR---D---YLQTIERSANNLLAI---INDILDFSKL 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 313 DSGR-PLERGPVDMsRLAVDAVSD--AHVAgpdHQWALDLP-------PEPVVipGDAARLHQVVTNLLANARVHTGPGT 382
Cdd:PRK11107 355 EAGKlVLENIPFSL-RETLDEVVTllAHSA---HEKGLELTlnidpdvPDNVI--GDPLRLQQIITNLVGNAIKFTESGN 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 383 I---VTTRLSTGpTHVVL--QVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPG 457
Cdd:PRK11107 429 IdilVELRALSN-TKVQLevQIRDTGIGISERQQSQLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPN 507
|
250
....*....|..
gi 888550169 458 Y-TEFAVRLPLD 468
Cdd:PRK11107 508 RgSTFWFHLPLD 519
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-457 |
2.20e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 80.32 E-value: 2.20e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAV 442
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGGTGLGLAIVKHV 80
|
90
....*....|....*
gi 888550169 443 VKAHNGTITVSSSPG 457
Cdd:cd16952 81 MSRHDARLLIASELG 95
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
251-315 |
2.33e-18 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 78.79 E-value: 2.33e-18
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 888550169 251 RQFVADASHELRTPLAAIRGYTELTQRIGDDPEaVAHAMSRVASETERITRLVEDLLLLARLDSG 315
Cdd:pfam00512 3 SEFLANLSHELRTPLTAIRGYLELLRDEKLDEE-QREYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
242-469 |
2.38e-18 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 87.15 E-value: 2.38e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 242 ARQASETRVRQFVADASHELRTPLAAIRGY-TELTQRIgdDPEAVAHAMSRV-ASETERITRLVEDLLLLARLDSGRPle 319
Cdd:PRK10364 229 KRKEKLVALGHLAAGVAHEIRNPLSSIKGLaKYFAERA--PAGGEAHQLAQVmAKEADRLNRVVSELLELVKPTHLAL-- 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 320 rGPVDMSRL---AVDAVS-DAHVAGpdhqWALDLPPEPVV--IPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPT 393
Cdd:PRK10364 305 -QAVDLNDLinhSLQLVSqDANSRE----IQLRFTANDTLpeIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGA 379
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 888550169 394 HVVLQVIDNGPGIPAALQSEVFerfargDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPLDG 469
Cdd:PRK10364 380 GVKISVTDSGKGIAADQLEAIF------TPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKgATFTLWLPVNI 450
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
247-311 |
8.79e-18 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 77.25 E-value: 8.79e-18
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 888550169 247 ETRVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLVEDLLLLAR 311
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
196-457 |
1.51e-17 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 84.23 E-value: 1.51e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 196 VDLPLDRGEVKLPVrvPEPDANPSTEVGQLGSALNRmLDHIAAALSARQASETRVRQFVAdasHELRTPL--AAIRGYT- 272
Cdd:PRK09303 103 GATYSGLGENLQPS--EIDSGRYSQELLQLSDELFV-LRQENETLLEQLKFKDRVLAMLA---HDLRTPLtaASLALETl 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 273 ELTQrIGDDPEAVAHAMSR----VASETERITRLVEDLLLLAR-LDSGRPLERGPVDMSRLAVDAVSD--AHVAGPDHQW 345
Cdd:PRK09303 177 ELGQ-IDEDTELKPALIEQlqdqARRQLEEIERLITDLLEVGRtRWEALRFNPQKLDLGSLCQEVILEleKRWLAKSLEI 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 346 ALDLPPE-PVVIpGDAARLHQVVTNLLANARVHTGP-GTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARgdT 423
Cdd:PRK09303 256 QTDIPSDlPSVY-ADQERIRQVLLNLLDNAIKYTPEgGTITLSMLHRTTQKVQVSICDTGPGIPEEEQERIFEDRVR--L 332
|
250 260 270
....*....|....*....|....*....|....
gi 888550169 424 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPG 457
Cdd:PRK09303 333 PRDEGTEGYGIGLSVCRRIVRVHYGQIWVDSEPG 366
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
251-315 |
2.87e-17 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 75.68 E-value: 2.87e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 888550169 251 RQFVADASHELRTPLAAIRGYTELTQRiGDDPEAVAHAMSRVASETERITRLVEDLLLLARLDSG 315
Cdd:smart00388 3 REFLANLSHELRTPLTAIRGYLELLLD-TELSEEQREYLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-457 |
3.26e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 77.12 E-value: 3.26e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 359 DAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERF---ARGDTSRSrqagSTGLG 435
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFyslPRPHSGQK----STGLG 76
|
90 100
....*....|....*....|..
gi 888550169 436 LAIVSAVVKAHNGTITVSSSPG 457
Cdd:cd16945 77 LAFVQEVAQLHGGRITLRNRPD 98
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-467 |
4.90e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 76.31 E-value: 4.90e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANARVHTGPGTIVTTRLSTGptHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAV 442
Cdd:cd16939 1 MARALDNLLRNALRYAHRTVRIALLVSGG--RLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGGFGLGLAIVHRV 78
|
90 100
....*....|....*....|....*.
gi 888550169 443 VKAHNGTITVSSSP-GYTEFAVRLPL 467
Cdd:cd16939 79 ALWHGGHVECDDSElGGACFRLTWPR 104
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
361-467 |
1.05e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 75.54 E-value: 1.05e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 361 ARLHQVVTNLLANArVHT--GPGTIvTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFArgdTSRSRQAGsTGLGLAI 438
Cdd:cd16943 2 SQLNQVLLNLLVNA-AQAmeGRGRI-TIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFF---TTKPVGEG-TGLGLSL 75
|
90 100 110
....*....|....*....|....*....|
gi 888550169 439 VSAVVKAHNGTITVSSSPGY-TEFAVRLPL 467
Cdd:cd16943 76 SYRIIQKHGGTIRVASVPGGgTRFTIILPI 105
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-467 |
5.12e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 73.51 E-value: 5.12e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANArVHTGPGTIvttRLSTGPT--HVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVS 440
Cdd:cd16949 1 LARALENVLRNA-LRYSPSKI---LLDISQDgdQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGGTGLGLAIAE 76
|
90 100
....*....|....*....|....*...
gi 888550169 441 AVVKAHNGTITVS-SSPGYTEFAVRLPL 467
Cdd:cd16949 77 RAIEQHGGKIKASnRKPGGLRVRIWLPA 104
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
244-467 |
9.75e-16 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 78.20 E-value: 9.75e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 244 QASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDDPeAVAHAMSRVASETERITRLVEDLLllarldsgrplerGPV 323
Cdd:PRK11073 124 HAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPDP-ALTEYTKVIIEQADRLRNLVDRLL-------------GPQ 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 324 DMSRLAVDAVSdaHVAGPDHQW-ALDLPPEPVVI----------PGDAARLHQVVTNLLANARVHTGP--GTIvTTRLST 390
Cdd:PRK11073 190 RPGTHVTESIH--KVAERVVQLvSLELPDNVRLIrdydpslpelAHDPDQIEQVLLNIVRNALQALGPegGTI-TLRTRT 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 391 -------GPTHVV---LQVIDNGPGIPAALQSEVFERFARGdtsrsrQAGSTGLGLAIVSAVVKAHNGTITVSSSPGYTE 460
Cdd:PRK11073 267 afqltlhGERYRLaarIDIEDNGPGIPPHLQDTLFYPMVSG------REGGTGLGLSIARNLIDQHSGKIEFTSWPGHTE 340
|
....*..
gi 888550169 461 FAVRLPL 467
Cdd:PRK11073 341 FSVYLPI 347
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
253-467 |
1.28e-15 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 79.60 E-value: 1.28e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 253 FVADASHELRTPLAAIRGY------TELTqrigddPEAVAHaMSRVASETERITRLVEDLLLLARLDSGR-PLERGPVDM 325
Cdd:PRK11091 286 FISTISHELRTPLNGIVGLsrilldTELT------AEQRKY-LKTIHVSAITLGNIFNDIIDMDKMERRKlQLDNQPIDF 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 326 SRLAVDAVSDAHVAGPDHQWALDL---PPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDN 402
Cdd:PRK11091 359 TDFLADLENLSGLQAEQKGLRFDLeplLPLPHKVITDGTRLRQILWNLISNAVKFTQQGGVTVRVRYEEGDMLTFEVEDS 438
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 888550169 403 GPGIPAALQSEVFERFAR-GDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPL 467
Cdd:PRK11091 439 GIGIPEDELDKIFAMYYQvKDSHGGKPATGTGIGLAVSKRLAQAMGGDITVTSEEGKgSCFTLTIHA 505
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
344-465 |
1.64e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 72.93 E-value: 1.64e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 344 QWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDT 423
Cdd:cd16947 2 QVEINIPDRPIYANANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLED 81
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 888550169 424 SRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRL 465
Cdd:cd16947 82 SRNSAKQGNGLGLTITKRLAESMGGSIYVNSKPYEkTVFTVTL 124
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-457 |
1.84e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 72.10 E-value: 1.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANARVHTGPGtiVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSrqAGSTGLGLAIVSAV 442
Cdd:cd16950 1 LKRVLSNLVDNALRYGGGW--VEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNARG--TSGTGLGLAIVQRI 76
|
90
....*....|....*
gi 888550169 443 VKAHNGTITVSSSPG 457
Cdd:cd16950 77 SDAHGGSLTLANRAG 91
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-466 |
3.72e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 71.26 E-value: 3.72e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANARVHTGPGTIV-TTRLSTGpTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRsrQAGSTGLGLAIVSA 441
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPENTRIyITSFLTD-DVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSR--NTEGAGLGLSIAKA 77
|
90 100
....*....|....*....|....*
gi 888550169 442 VVKAHNGTITVSSSPGYTEFAVRLP 466
Cdd:cd16923 78 IIELHGGSASAEYDDNHDLFKVRLP 102
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
347-465 |
1.40e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 70.35 E-value: 1.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 347 LDLPPEpVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLstGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRS 426
Cdd:cd16954 23 LDISPE-LRFPGERNDLMELLGNLLDNACKWCLEFVEVTARQ--TDGGLHLIVDDDGPGVPESQRSKIFQRGQRLDEQRP 99
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 888550169 427 RQagstGLGLAIVSAVVKAHNGTITVSSSP-GYTEFAVRL 465
Cdd:cd16954 100 GQ----GLGLAIAKEIVEQYGGELSLSDSPlGGARFEVVF 135
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
147-455 |
3.72e-13 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 71.64 E-value: 3.72e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 147 NVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALapLRRVAQTASEVVDLPldRGEVKLPVRVPEPDanpstEVGQLG 226
Cdd:COG4192 316 ETAQLVQQSGILLLAIALLSLLLAVLINYFYVRRRL--VKRLNALSDAMAAIA--AGDLDVPIPVDGND-----EIGRIA 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 227 SALNRMLDHIAAA-------LSARQASETRVRQ------------FVADA----SHELRTPLAAIRGY--TELTQRIGDD 281
Cdd:COG4192 387 RLLRVFRDQAIEKtqeleteIEERKRIEKNLRQtqdeliqaakmaVVGQTmtslAHELNQPLNAMSMYlfSAKKALEQEN 466
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 282 PEAVAHAMSRVASETERITRLVEDLLLLARlDSGRPLerGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVViPGDAA 361
Cdd:COG4192 467 YAQLPTSLDKIEGLIERMDKIIKSLRQFSR-KSDTPL--QPVDLRQVIEQAWELVESRAKPQQITLHIPDDLMV-QGDQV 542
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 362 RLHQVVTNLLANA-RVHTGPGTIVTTRLSTGPTHVVLqVIDNGPGIPAAlqSEVFERFargdtSRSRQAGsTGLGLAIVS 440
Cdd:COG4192 543 LLEQVLVNLLVNAlDAVATQPQISVDLLSNAENLRVA-ISDNGNGWPLV--DKLFTPF-----TTTKEVG-LGLGLSICR 613
|
330
....*....|....*
gi 888550169 441 AVVKAHNGTITVSSS 455
Cdd:COG4192 614 SIMQQFGGDLYLAST 628
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
215-456 |
1.35e-12 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 69.66 E-value: 1.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 215 DANPSTEVGQLGSALNRMLDhiaaalSARQaSETRVRQFVADASHELRTPLA-------AIRGYTELTqrigddpeaVAH 287
Cdd:PRK10815 238 DPNPPRELTSLVRNLNRLLK------NERE-RYTKYRTTLTDLTHSLKTPLAvlqstlrSLRSGKQMS---------VEQ 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 288 AMSRVASETERITRLVEDLLLLARLDSGRPLergpvdMSR--LAVDAVSDAHVAGPDHQW-------ALDLPPEPVVIpG 358
Cdd:PRK10815 302 AEPIMLEQISRISQQIGYYLHRASMRSEHNL------LSRelHSVAPLLDNLTSALNKVYqrkgvniTLDISPEITFV-G 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 359 DAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVlqVIDNGPGIPAALQSEVFERFARGDTSRSRQagstGLGLAI 438
Cdd:PRK10815 375 EKNDFMEVMGNVLDNACKYCLEFVEISARQTDEHLHIV--VEDDGPGIPESKRELIFDRGQRADTLRPGQ----GLGLSV 448
|
250
....*....|....*...
gi 888550169 439 VSAVVKAHNGTITVSSSP 456
Cdd:PRK10815 449 AREITEQYEGKISAGDSP 466
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-466 |
3.51e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 62.73 E-value: 3.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANARVHTGPG-----TIVTTRLSTGPThvvLQVIDNGPGIPAALQSEVFERFARGDtSRSRQAGsTGLGLA 437
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRrppriEVGAEDVGEEWT---FYVRDNGIGIDPEYAEKVFGIFQRLH-SREEYEG-TGVGLA 75
|
90 100 110
....*....|....*....|....*....|
gi 888550169 438 IVSAVVKAHNGTITVSSSPGY-TEFAVRLP 466
Cdd:cd16921 76 IVRKIIERHGGRIWLESEPGEgTTFYFTLP 105
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
366-466 |
3.63e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 59.61 E-value: 3.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 366 VVTNLLANARVHTG----PGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFErfaRGDTSRSrqAGSTGLGLAIVSA 441
Cdd:cd16915 4 IVGNLIDNALDALAatgaPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFE---RGVSTKG--QGERGIGLALVRQ 78
|
90 100
....*....|....*....|....*.
gi 888550169 442 VVKAHNGTITVSSSP-GYTEFAVRLP 466
Cdd:cd16915 79 SVERLGGSITVESEPgGGTTFSIRIP 104
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-466 |
4.42e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 59.89 E-value: 4.42e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANARVHTGPGT--IVTTRLSTGPTHVVLqVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVS 440
Cdd:cd16953 1 LGQVLRNLIGNAISFSPPDTgrITVSAMPTGKMVTIS-VEDEGPGIPQEKLESIFDRFYTERPANEAFGQHSGLGLSISR 79
|
90 100 110
....*....|....*....|....*....|.
gi 888550169 441 AVVKAHNGTITVS--SSPGY---TEFAVRLP 466
Cdd:cd16953 80 QIIEAHGGISVAEnhNQPGQvigARFTVQLP 110
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
115-467 |
1.13e-10 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 63.50 E-value: 1.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 115 LTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPLRRVAQTASE 194
Cdd:COG2972 115 LSILLLILGLLLIILLLLSLLGWTLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKK 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 195 VVDLPLDRGEVklpvrvpepdaNPSTEVGQLGSALNRMLDHIAAALSARQASETRVRQFvadashELRT------P---- 264
Cdd:COG2972 195 VEKGDLVRLEV-----------SGNDEIGILARSFNEMVERIKELIEEVYELELEKKEA------ELKAlqaqinPhflf 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 265 --LAAIRGYTeltqRIGDDPEA--VAHAMSR-----VASETERIT-----RLVEDLLLL--ARLDSgrplergpvdmsRL 328
Cdd:COG2972 258 ntLNSIRWLA----ELEDPEEAeeMLEALSKllrysLSKGDELVTleeelELIKSYLEIqkLRFGD------------RL 321
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 329 AVDavsdahvagpdhqwaLDLPPEP--VVIPgdaARLHQVvtnLLANARVH-----TGPGTI-VTTRLSTGptHVVLQVI 400
Cdd:COG2972 322 EVE---------------IEIDEELldLLIP---KLILQP---LVENAIEHgiepkEGGGTIrISIRKEGD--RLVITVE 378
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 888550169 401 DNGPGIPAALQSEVFERFargdtsrSRQAGSTGLGLAIVSAVVKAHNG---TITVSSSPG-YTEFAVRLPL 467
Cdd:COG2972 379 DNGVGMPEEKLEKLLEEL-------SSKGEGRGIGLRNVRERLKLYYGeeyGLEIESEPGeGTTVTIRIPL 442
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-457 |
5.84e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 56.39 E-value: 5.84e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 359 DAARLHQVVTNLLANAR-----VHTGPGTiVTTRLSTG-PTHVVLQVIDNGPGIPAALQSEVFERFArgdTSRSRqagST 432
Cdd:cd16944 1 DTTQISQVLTNILKNAAeaiegRPSDVGE-VRIRVEADqDGRIVLIVCDNGKGFPREMRHRATEPYV---TTRPK---GT 73
|
90 100
....*....|....*....|....*
gi 888550169 433 GLGLAIVSAVVKAHNGTITVSSSPG 457
Cdd:cd16944 74 GLGLAIVKKIMEEHGGRISLSNREA 98
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-466 |
1.08e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 55.48 E-value: 1.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLAN---ARVHTGP-GTIVTTRLST-GPTHVVLQVIDNGPGIPAALQSEVFERFArgdtsrSRQAGSTGLGLA 437
Cdd:cd16920 1 IQQVLINLVRNgieAMSEGGCeRRELTIRTSPaDDRAVTISVKDTGPGIAEEVAGQLFDPFY------TTKSEGLGMGLS 74
|
90 100 110
....*....|....*....|....*....|
gi 888550169 438 IVSAVVKAHNGTITVSSSP-GYTEFAVRLP 466
Cdd:cd16920 75 ICRSIIEAHGGRLSVESPAgGGATFQFTLP 104
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-465 |
1.16e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 55.54 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANA--RVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFArgdTSRSRQAGsTGLGLAIVS 440
Cdd:cd16976 1 IQQVLMNLLQNAldAMGKVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFF---TTKPVGKG-TGLGLSISY 76
|
90 100
....*....|....*....|....*.
gi 888550169 441 AVVKAHNGTITVSS-SPGYTEFAVRL 465
Cdd:cd16976 77 GIVEEHGGRLSVANeEGAGARFTFDL 102
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-466 |
1.23e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 55.75 E-value: 1.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 359 DAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAgSTGLGLAI 438
Cdd:cd16948 2 DAKWLSFIIGQIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRNFQE-STGMGLYL 80
|
90 100
....*....|....*....|....*....
gi 888550169 439 VSAVVKAHNGTITVSSSPG-YTEFAVRLP 466
Cdd:cd16948 81 VKKLCDKLGHKIDVESEVGeGTTFTITFP 109
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
323-466 |
2.78e-09 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 59.46 E-value: 2.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 323 VDMSRlavDAVSDAHVAG---PDHQWALDLPPEPVVIPGdaARLHQ------------VVTNLLANA-----RVHTGpGT 382
Cdd:PRK15053 383 IDSLR---EAFADRQVAGllfGKVQRARELGLKMVIVPG--SQLSQlppgldstefaaIVGNLLDNAfeaslRSDEG-NK 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 383 IVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFErfaRGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEF 461
Cdd:PRK15053 457 IVELFLSDEGDDVVIEVADQGCGVPESLRDKIFE---QGVSTRADEPGEHGIGLYLIASYVTRCGGVITLEDNDPCgTLF 533
|
....*
gi 888550169 462 AVRLP 466
Cdd:PRK15053 534 SIFIP 538
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
8-472 |
5.40e-09 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 58.38 E-value: 5.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 8 AATEMALRRHLVAQLDNQLGGTSYRSVLMYPEKMPRPPWRHETHNYIRSGPGPRFLDAPGQPAGMVAAVVSDGTTVAAGY 87
Cdd:COG3920 56 LALSAAALAAALAVALAAAVGAAAALLALLVLLLLLLLAAAALALALLLAALAGLLLLAALLLLRLVALLAALALLALLL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 88 LTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVTVIAL 167
Cdd:COG3920 136 LLLLLLAILALAELAVALAELAAALLLLAEELAALRLAAAALLLLLAALLDLGLALAALAAAALLALLLALELLLALLLL 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 168 VAATTAGIVIIKRALAPLRRVAQTASEVVDLPLDRGEVKLPVRVPEPDANpstEVGQLGSALNRMLDHIAAALSARQASE 247
Cdd:COG3920 216 LLLLLALLLVLLAALLRLRAAVLEELERRRRARGLGRLLLLLLLLLLLLR---ALLLLAAGIRLVITERKRAEEELEASL 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 248 TRVRQFVADASHELRTPLAAIRGYTELTQRIGDDPE---AVAHAMSRVASeteriTRLVEDLLLlarldsgRPLERGPVD 324
Cdd:COG3920 293 EEKELLLRELHHRVKNNLQVVSSLLRLQARRADDPEareALEESQNRIQA-----LALVHELLY-------QSEDWEGVD 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 325 MSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAAR-----LHQVVTNLLANARVHTGPGTIvTTRLSTGPTHVVLQV 399
Cdd:COG3920 361 LRDYLRELLEPLRDSYGGRGIRIELDGPDVELPADAAVplgliLNELVTNALKHAFLSGEGGRI-RVSWRREDGRLRLTV 439
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 888550169 400 IDNGPGIPAALQSEvferfargdtsrsrqaGSTGLGLAIVSAVVKAHNGTITVSSSPGyTEFAVRLPLDGWQP 472
Cdd:COG3920 440 SDNGVGLPEDVDPP----------------ARKGLGLRLIRALVRQLGGTLELDRPEG-TRVRITFPLAELAA 495
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
265-469 |
1.13e-08 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 55.78 E-value: 1.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 265 LAAIRGYTELTQR-IGDDPEAVAHAMSRVASETERITRLVEDLLllARLDSGRPLERG-PVDMSRLAVDAVSDAHVagpd 342
Cdd:COG4585 69 LSAIKLQLEAARRlLDADPEAAREELEEIRELAREALAELRRLV--RGLRPPALDDLGlAAALEELAERLLRAAGI---- 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 343 hQWALDLPPEPVVIPGDAAR-LHQVVTNLLANARVHtGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAAlqsevferfarg 421
Cdd:COG4585 143 -RVELDVDGDPDRLPPEVELaLYRIVQEALTNALKH-AGATRVTVTLEVDDGELTLTVRDDGVGFDPE------------ 208
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 888550169 422 dtsrsrQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPLDG 469
Cdd:COG4585 209 ------AAPGGGLGLRGMRERAEALGGTLTIGSAPGGgTRVRATLPLAA 251
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
258-457 |
1.32e-08 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 56.99 E-value: 1.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 258 SHELRTPLAAIRGYTELTQRIGD----DPEAVAHAMSRVASETERITRLVEDLLLLAR---LDsGRPLE-----RGPVDM 325
Cdd:PRK13557 171 AHDFNNLLQVMSGYLDVIQAALShpdaDRGRMARSVENIRAAAERAATLTQQLLAFARkqrLE-GRVLNlnglvSGMGEL 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 326 SRLAV-DAVSDAHVAGPDhqwaldLPPEPVvipgDAARLHQVVTNLLANAR---VHTGPGTIVTTRLSTGPT-------- 393
Cdd:PRK13557 250 AERTLgDAVTIETDLAPD------LWNCRI----DPTQAEVALLNVLINARdamPEGGRVTIRTRNVEIEDEdlamyhgl 319
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 888550169 394 ----HVVLQVIDNGPGIPAALQSEVFERFArgdTSRSRQAGsTGLGLAIVSAVVKAHNGTITVSSSPG 457
Cdd:PRK13557 320 ppgrYVSIAVTDTGSGMPPEILARVMDPFF---TTKEEGKG-TGLGLSMVYGFAKQSGGAVRIYSEVG 383
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-455 |
1.62e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 52.46 E-value: 1.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 359 DAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRsRQAGSTGLGLAI 438
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSR-RSGGHYGMGLYI 79
|
90
....*....|....*..
gi 888550169 439 VSAVVKAHNGTITVSSS 455
Cdd:cd16975 80 AKNLVEKHGGSLIIENS 96
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
355-476 |
8.75e-08 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 54.53 E-value: 8.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 355 VIP--GDAARLHQVVT---NLLANA--RVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFER-FARGDTSRs 426
Cdd:PRK11086 421 QLPdsGDEDQVHELITilgNLIENAleAVGGEEGGEISVSLHYRNGWLHCEVSDDGPGIAPDEIDAIFDKgYSTKGSNR- 499
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 888550169 427 rqagstGLGLAIVSAVVKAHNGTITVSSSPG-YTEFAVRLPldgWQPLESS 476
Cdd:PRK11086 500 ------GVGLYLVKQSVENLGGSIAVESEPGvGTQFFVQIP---WDGERSN 541
|
|
| HATPase_Phy-like |
cd16932 |
Histidine kinase-like ATPase domain of plant phytochromes similar to Arabidopsis thaliana ... |
358-450 |
1.10e-06 |
|
Histidine kinase-like ATPase domain of plant phytochromes similar to Arabidopsis thaliana Phytochrome A, B, C, D and E; This family includes the histidine kinase-like ATPase (HATPase) domains of plant red/far-red photoreceptors, the phytochromes, and includes the Arabidopsis thaliana phytochrome family phyA-phyE. Following red light absorption, biologically inactive forms of phytochromes convert to active forms, which rapidly convert back to inactive forms upon far-red light irradiation. Phytochromes can be considered as having an N-terminal photosensory region to which a bilin chromophore is bound, and a C-terminal output region, which includes the HATPase domain represented here, and is involved in dimerization and presumably contributes to relaying the light signal to downstream signaling events.
Pssm-ID: 340409 [Multi-domain] Cd Length: 113 Bit Score: 47.27 E-value: 1.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 358 GDAARLHQVVTNLLANARVHT-GPGTIVTTRLSTGPT---------HVVLQVIDNGPGIPAALQSEVFERfaRGDTSRSr 427
Cdd:cd16932 2 GDQIRLQQVLADFLLNAVRFTpSPGGWVEIKVSPTKKqigdgvhviHLEFRITHPGQGLPEELVQEMFEE--NQWTTQE- 78
|
90 100
....*....|....*....|...
gi 888550169 428 qagstGLGLAIVSAVVKAHNGTI 450
Cdd:cd16932 79 -----GLGLSISRKLVKLMNGDV 96
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-466 |
7.17e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 44.08 E-value: 7.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANARVHTGPGTiVTTRLSTGPTHVVLQVIDNGPGIPAALQSevferfargdtsrsrqaGSTGLGLAIVSAV 442
Cdd:cd16917 1 LYRIVQEALTNALKHAGASR-VRVTLSYTADELTLTVVDDGVGFDGPAPP-----------------GGGGFGLLGMRER 62
|
90 100
....*....|....*....|....*
gi 888550169 443 VKAHNGTITVSSSPGY-TEFAVRLP 466
Cdd:cd16917 63 AELLGGTLTIGSRPGGgTRVTARLP 87
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
363-466 |
8.17e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 44.68 E-value: 8.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 363 LHQVVTNLLANARVHTGPGTIVTTRLSTGPT---------------HVVLQVIDNGPGIPAALQSEVFERFArgdTSRSR 427
Cdd:cd16919 1 LELAILNLAVNARDAMPEGGRLTIETSNQRVdadyalnyrdlipgnYVCLEVSDTGSGMPAEVLRRAFEPFF---TTKEV 77
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 888550169 428 QAGsTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLP 466
Cdd:cd16919 78 GKG-TGLGLSMVYGFVKQSGGHLRIYSEPGVgTTVRIYLP 116
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
148-305 |
7.48e-05 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 45.01 E-value: 7.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 148 VDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPLRRVAQTASEVVDlpldrGEVKLPVRVPEPDanpstEVGQLGS 227
Cdd:COG0840 173 ALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAE-----GDLTVRIDVDSKD-----EIGQLAD 242
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 888550169 228 ALNRMLDHIAAALSA-RQASETrvrqfVADASHELRTplaairGYTELTQRIgddpEAVAHAMSRVASETERITRLVED 305
Cdd:COG0840 243 AFNRMIENLRELVGQvRESAEQ-----VASASEELAA------SAEELAAGA----EEQAASLEETAAAMEELSATVQE 306
|
|
| HAMP |
pfam00672 |
HAMP domain; |
176-236 |
8.38e-05 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 40.30 E-value: 8.38e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 888550169 176 VIIKRALAPLRRVAQTASEVvdlplDRGEVKLPVRVPEPDanpstEVGQLGSALNRMLDHI 236
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRI-----ASGDLDVRLPVSGRD-----EIGELARAFNQMAERL 51
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
74-452 |
9.84e-05 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 45.10 E-value: 9.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 74 AAVVSDGTTVAAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATML 153
Cdd:COG2770 129 AALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAAL 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 154 QMLIIFGIVTVIALVAATTAGIVIIKRALAPLRRVAQTASEVvdlplDRGEVKLPVRVPEPDanpstEVGQLGSALNRML 233
Cdd:COG2770 209 AALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRI-----AAGDLDVRIPVSRKD-----EIGELARAFNRMA 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 234 DHIAAALSARQASE-TRVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLVEDLLLLARL 312
Cdd:COG2770 279 DSLRESIEEAEEEEeLAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAA 358
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 313 DSGRPLERGPVDMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGP 392
Cdd:COG2770 359 LLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAAAL 438
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 393 THVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITV 452
Cdd:COG2770 439 ELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEA 498
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
346-467 |
3.21e-04 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 40.67 E-value: 3.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 346 ALDLPPEpvvipgDAARLHQVVTNLLANARVHTG---PGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGd 422
Cdd:COG2172 24 ELGLDED------DADDLVLAVSEAVTNAVRHAYggdPDGPVEVELELDPDGLEIEVRDEGPGFDPEDLPDPYSTLAEG- 96
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 888550169 423 tsrsrqagstGLGLAIVSAVVKAhngtITVSSSPGYTEFAVRLPL 467
Cdd:COG2172 97 ----------GRGLFLIRRLMDE----VEYESDPGGTTVRLVKRL 127
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
179-241 |
3.37e-04 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 38.38 E-value: 3.37e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 888550169 179 KRALAPLRRVAQTASEVVDLPLDrgevklpVRVPEPDANpstEVGQLGSALNRMLDHIAAALS 241
Cdd:smart00304 1 RRLLRPLRRLAEAAQRIADGDLT-------VRLPVDGRD---EIGELARAFNEMADRLEETIA 53
|
|
| ActS_PrrB_HisK |
NF033792 |
ActS/PrrB/RegB family redox-sensitive histidine kinase; This redox-responsive histidine kinase, ... |
237-436 |
4.45e-04 |
|
ActS/PrrB/RegB family redox-sensitive histidine kinase; This redox-responsive histidine kinase, found in alpha-proteobacteria, shows strong sequence conservation, including the notable motif [VA]AAAAHELGTPxTI. It always acts as a partner to an ActR/PrrA/RegA family global response regulator transcription factor in a two-component sensory transduction system. Lineage-specific names and gene symbols given to this histidine kinase reflect downstream regulator changes such as entry into stationary phase, anaerobic expression of photosynthesis genes, and survival of exposure to low pH.
Pssm-ID: 468186 [Multi-domain] Cd Length: 423 Bit Score: 42.50 E-value: 4.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 237 AAALSARQ---ASETRVRQF---VADASHELRTPLAAIRGYT-ELTQRIGDDPEaVAHAMSRVASETER-------ITRL 302
Cdd:NF033792 183 SDALAATElvlAREQHLSALdglAAAAAHELGTPLATIALVAkELERELPDDPP-LREDAELLRSQAERcrdilrrLTSL 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 303 VEdllllarlDSGRPLERGPVdmsRLAVDAVSDAHVA-GPDHQWALDLPP--EPVVIPgDAARLHQvVTNLLAN----AR 375
Cdd:NF033792 262 GE--------EGDAHLDRLPL---SALIEEAAAPHRGfGKEIEVVVAGDPgeEPVIRR-NPEILYG-LGNLIENavdfAR 328
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 888550169 376 vhtgpgTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQAGSTGLGL 436
Cdd:NF033792 329 ------STVTVTASWDAESVTITIEDDGPGFPPDVLSRIGEPYVTTRRGEERRPGGGGLGL 383
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
251-467 |
4.85e-04 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 42.61 E-value: 4.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 251 RQFVADASHELRTPLAAIrgyTELTQRIGD-DPEAVAHAMSRV-ASETERITRLVEDLLLLARLDSGR-PLERGPVDMSR 327
Cdd:PRK10618 451 KAFLQNIGDELKQPLQSL---AQLAAQLRQtSDEEQQQPELDQlAEQSDVLVRLVDNIQLLNMLETQDwKPEQELFSLQD 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 328 LAVDAVSDA-------------HVAgpdhqwaldLPPEPVVIpGDAARLHQVVTNLLANARVHTGPGTI-VTTRLSTG-P 392
Cdd:PRK10618 528 LIDEVLPEVlpaikrkglqlliHNH---------LKAEQLRI-GDRDALRKILLLLLNYAITTTAYGKItLEVDQDESsP 597
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 888550169 393 THVVLQVIDNGPGIPAALQSEVFERFArGDTSRSRQAGSTGLGLAIVSAVVKAHNGTITVSSSPGY-TEFAVRLPL 467
Cdd:PRK10618 598 DRLTIRILDTGAGVSIKELDNLHFPFL-NQTQGDRYGKASGLTFFLCNQLCRKLGGHLTIKSREGLgTRYSIHLKM 672
|
|
| HATPase_TopVIB-like |
cd16933 |
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family ... |
364-468 |
7.58e-04 |
|
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family includes the histidine kinase-like ATPase (HATPase) domain of the B subunit of topoisomerase VI (Topo VIB). Topo VI is a heterotetrameric complex composed of two TopVIA and two TopVIB subunits and is categorized as a type II B DNA topoisomerase. It is found in archaea and also in plants. Type II enzymes cleave both strands of a DNA duplex and pass a second duplex through the resulting break in an ATP-dependent mechanism. DNA cleavage by Topo VI generates two-nucleotide 5'-protruding ends.
Pssm-ID: 340410 [Multi-domain] Cd Length: 203 Bit Score: 40.79 E-value: 7.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 364 HQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVFERFARGDTSRSRQA-GSTGLGlaiVSAV 442
Cdd:cd16933 25 RELVENSLDATEEAGILPDIKVEIEEIGKDHYKVIVEDNGPGIPEEQIPKVFGKVLYGSKYHNKQSrGQQGLG---ISAA 101
|
90 100 110
....*....|....*....|....*....|..
gi 888550169 443 V---KAHNGT-ITVSSSPGYTEFA--VRLPLD 468
Cdd:cd16933 102 VlysQMTTGKpVEIISSTKDSNYAyvVKLMID 133
|
|
| PRK13560 |
PRK13560 |
hypothetical protein; Provisional |
366-467 |
7.75e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 106506 [Multi-domain] Cd Length: 807 Bit Score: 41.97 E-value: 7.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 366 VVTNLLANARVHTGP----GTIVTTRLSTGPTHVVLQVIDNGPGIPAALQsevferFARGDTsrsrqagstgLGLAIVSA 441
Cdd:PRK13560 715 IISELLSNALKHAFPdgaaGNIKVEIREQGDGMVNLCVADDGIGLPAGFD------FRAAET----------LGLQLVCA 778
|
90 100
....*....|....*....|....*.
gi 888550169 442 VVKAHNGTITVSSSPGyTEFAVRLPL 467
Cdd:PRK13560 779 LVKQLDGEIALDSRGG-ARFNIRFPM 803
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
84-401 |
3.19e-03 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 39.87 E-value: 3.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 84 AAGYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLGRYRVLAAPSRNGHDVIVTGLSMGNVDATMLQMLIIFGIVT 163
Cdd:COG3850 45 LLSLLASAGLLAALLAALLLLLSLGLLALLLALLLLLLLLLLAALLSLLLLLLLLLLLLLLLLLLLLAAAINRKLALLRL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 164 VIALVAATTAGIVIIKRALAPLRRVAQTASEVvdlplDRGEVKLPVRVPEPDanpstEVGQLGSALNRMLDHIAAALSAR 243
Cdd:COG3850 125 LLALLLALLLAYLLRRRIVRPLRRLTQAAERI-----ARGDFDARVPVSGRD-----ELGTLARAFNRMADELQELYAEL 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 888550169 244 QASETRVRQFVADASHELRTPLAAIRGYTELTQRIGDDPEAVAHAMSRVASETERITRLVEDLLLLARLDSGRPLERGPV 323
Cdd:COG3850 195 EEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLL 274
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 888550169 324 DMSRLAVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHTGPGTIVTTRLSTGPTHVVLQVID 401
Cdd:COG3850 275 ASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASILALQAA 352
|
|
| PRK04184 |
PRK04184 |
DNA topoisomerase VI subunit B; Validated |
382-443 |
9.30e-03 |
|
DNA topoisomerase VI subunit B; Validated
Pssm-ID: 235246 [Multi-domain] Cd Length: 535 Bit Score: 38.33 E-value: 9.30e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 888550169 382 TIVTTRLSTGPTHVVLQVIDNGPGIPAALQSEVF------ERFARGDTSRSRQagstGLGlaiVSAVV 443
Cdd:PRK04184 62 KIEIKRVDEGKDHYRVTVEDNGPGIPPEEIPKVFgkllygSKFHNLRQSRGQQ----GIG---ISAAV 122
|
|
| |
