|
Name |
Accession |
Description |
Interval |
E-value |
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
1-967 |
0e+00 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 721.76 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 1 MVGCWVALALVLPMAVPSLAEMAQRHPVAVLPADAPSSVAVRQMAEAFHESGSENILVVLLTDEKGLGAADENVYHTLVD 80
Cdd:TIGR00833 6 IIGVWIATAISLQLLAPLLEDVSYFRLQAELPGGAASSIAVKEMSAAFQEAIRDPKIILVLESNERLGDKDYATYDALIA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 81 RLRNDAKDVVMLQDFLTTPPLREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKRTVAGTTLTANVTGPAATVA 160
Cdd:TIGR00833 86 KLRADIMHVISVVDFWGPPEAAEGLRSDDGKATIIIVNLAGEKGQKEAQEAINAVRRIVEQTNAPDGLTVHVTGPLATIA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 161 DLTDAGARDRASIELAIAVMLLVILMVIYRNPVTMLLPLVTIGASLMTAQALVAGVSLVGGLAVSNQAIVLLSAMIAGAG 240
Cdd:TIGR00833 166 DILESGDKDMNRITATTGIIVLIILLLVYRSPITMLVPLVSVGFSVVVAQGIVSLLGIPGLIGVNAQTTVLLTALVIGAG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 241 TDYAVFLISRYHEYVRLGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTLL 320
Cdd:TIGR00833 246 TDYAVFLTGRYHEERRKGESLEEAAAEALRGTGKAILGSALTVAVAFLALSLARLPSFKTLGVSCAVGVLVALLNAVTLT 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 321 PAILVLASPRGWVAPRGERMATF-WRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYDDRKQLPPSDPSSVGYAAM 399
Cdd:TIGR00833 326 PALLTLEGREGLMKPGRKSKIRFiWRRLGTAVVRRPWPILVTTLIISGVSLLALPLIRTGYDDEKMIPTDLESVQGYEAA 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 400 EHHFSVNQAIPEYLIIHSAHDLRTPRGLADLEQLAQRVSQIPGVAMVRGVTRPNGETLEQARATYQAGQVGNRLGGASRM 479
Cdd:TIGR00833 406 DRHFPGNSMDPMVVMIKSDHDVRNPALLADIDRFEREIKAVPGINMVQETQRPDGVVIKKTYLTFQAGNLGDQLDEFSDQ 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 480 IDERTGDLNRlasganlLADNLGDVRGQVSRAVAGVRSLVdalayiqnqfggnktfneiDNAARLVSNIHALGDALQVNF 559
Cdd:TIGR00833 486 LTSRQAYLLQ-------DAEKIAEAIAGLRLVQAGMRLDG-------------------ENLGQVSLAVRLMQQAISKLQ 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 560 DGIANSFDWLDSVVAALDTSPVCDSNPMCGNARVQFHKLQTArdngtldkvvgLARQLQSTRSPQTVSAVVNDLGRSLNS 639
Cdd:TIGR00833 540 GSAGDVFDIFDPLRRFVAAIPECRANPVCSVAREIVQAADTV-----------VSSAAKLADAAGQLARGIADVASALSQ 608
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 640 VVRSLKSLgldnpDAARARLISMQNGANdlasagrQVADGVQMLVDQTKNMGIGLNQASAFLmamgndasqpsmagFNVP 719
Cdd:TIGR00833 609 VSGLPNAL-----DGIGTQLAQMRESAA-------GVQDLLNELSDYSMTMGKLKGNAMGVD--------------FYAP 662
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 720 PQVLKSEEFKKVAQAFISPDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAQPNTSLADASISMSGYPVMLRDIRDYY 799
Cdd:TIGR00833 663 PRIFTDPNFKAVLDYFLSPDGHAARLLVYGDGSPAGDQGAQEFNAIRTVAEEAIQRADLEPAKVELAGVSAVNRDLRDLV 742
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 800 ERDMRLIVAVTVVVVILILMALLRAIVAPLYLVGSVVISYMSAIGLGVVVFQVFLGQELHWSVPGLAFVVLVAVGADYNM 879
Cdd:TIGR00833 743 NSDLGLISIITLAIVFMILALLLRAPVAPIVLIGSVALSYLWALGLSVLAFQHILGAELHWSVLAGVFVLLVALGVDYNM 822
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 880 LLASRLRDESALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFIIGVGILIDTFVVRTITVPAMATL 959
Cdd:TIGR00833 823 LLVSRIKEESPAGNRTGIIRALGSTGGVITAAGLVFAGTMAALASAQLTAIAQFGFTVGVGILLDTFIVRSVTVPALTLL 902
|
....*...
gi 887957230 960 LGRASWWP 967
Cdd:TIGR00833 903 LGRWIWWP 910
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
29-358 |
7.02e-117 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 361.99 E-value: 7.02e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 29 AVLPADAPSSVAVRQMAEAFHESGSENILVVLL-TDEKGLG-AADENVYHTLVDRLRNDAKDVVMLQDFLTTPPLREVLG 106
Cdd:pfam03176 1 ALSPADAPSVRAMDRLGAAFPQADSDPIIVVVLgEGDQALGdAAAEAGYDTLVDALRADTGHVGSVQDFWGDPDTAALFV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 107 SKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKRTVAGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILM 186
Cdd:pfam03176 81 SPDGKAAYVVVTLEGDPGTTEADESVAAVRDAVEQAPPPEGLKAYLTGPAATVADLRDAGDRDLGLIEAVTLVVIFIILL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 187 VIYRNPVTMLLPLVTIGASLMTAQALVAGVSLVGGLAVSNQAIVLLSAMIAGAGTDYAVFLISRYHEYVRLGEHPERAVQ 266
Cdd:pfam03176 161 IVYRSVVAALLPLLTVGLSLGAAQGLVAILAHILGIGLSTFALNLLVVLLIAVGTDYALFLVSRYREELRAGEDREEAVI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 267 RAMMSVGKVIAASAATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLASPRGWVAPRGERMATFWRR 346
Cdd:pfam03176 241 RAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVDVLAALTLLPALLALLGRWGLWPPKRDRTARWWRR 320
|
330
....*....|..
gi 887957230 347 AGTRIVRRPKAY 358
Cdd:pfam03176 321 IGRLVVRRPAPV 332
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
2-455 |
2.30e-102 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 335.97 E-value: 2.30e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 2 VGCWVALALVLPMAVPSLAE-MAQRHpvAVLPADaPSSVAVRQMAEAFHESGSENILVVLLTDEKGLGAAD-ENVYHTLV 79
Cdd:COG2409 9 LLAWLVLLVALGVLAPQLGGsLSSNG--FFLPGS-ESQRAADLLAEAFPESDGASAVVVVEAPDGTLTDPAfRAAVAALV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 80 DRLRNDaKDVVMLQDFLTTPPLREVlgSKDGKAWILPIGLAGDLGTpKSYHAYTDVERIVKRtVAGTTLTANVTGPAATV 159
Cdd:COG2409 86 ARLRAD-PGVAGVQDPWDDPAAGLV--SEDGKAALVTVTLDGDAGD-EAAEAVDALRDAVAA-APAPGLTVYVTGPAALA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 160 ADLTDAGARDRASIELAIAVMLLVILMVIYRNPVTMLLPLVTIGASLMTAQALVAGVSLVggLAVSNQAIVLLSAMIAGA 239
Cdd:COG2409 161 ADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLLTAGLAVGVALGLLALLAAF--TDVSSFAPNLLTMLGLGV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 240 GTDYAVFLISRYHEYVRLGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTL 319
Cdd:COG2409 239 GIDYALFLVSRYREELRAGEDREEAVARAVATAGRAVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVAVLAALTL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 320 LPAILVLASPRG------WVAPRGERMATFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYDDRKQLPPSDPSS 393
Cdd:COG2409 319 LPALLALLGRRVfwprrpRRRRAAAPESGFWRRLARAVVRRPVPVLVAAVAVLLALALPALGLRLGLPDADSLPADSPSR 398
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 887957230 394 VGYAAMEHHFSVNQAIPEYLIIHSAHDLrTPRGLADLEQLAQRVSQIPGVAMVRGVTRPNGE 455
Cdd:COG2409 399 QGYDALAEHFPPGSNGPLTVVVESDDDL-DPADLAALDALAAALAAVPGVASVQPPTRPEGT 459
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
632-970 |
1.36e-59 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 207.53 E-value: 1.36e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 632 DLGRSLNSVVRSLKSLGLDNPDAARARLISMQNGANDLASAGRQVADGVQMLVDQTKNMGIGLNQASAFlmamgndasqp 711
Cdd:pfam03176 1 ALSPADAPSVRAMDRLGAAFPQADSDPIIVVVLGEGDQALGDAAAEAGYDTLVDALRADTGHVGSVQDF----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 712 smagFNVPPqvlkseefkkVAQAFISPDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAQPntsLADASISMSGYPVM 791
Cdd:pfam03176 70 ----WGDPD----------TAALFVSPDGKAAYVVVTLEGDPGTTEADESVAAVRDAVEQAPP---PEGLKAYLTGPAAT 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 792 LRDIRDYYERDMRLIVAVTVVVVILILMALLRAIVAPLYLVGSVVISYMSAIGLgVVVFQVFLGQELHWSVPGLAFVVLV 871
Cdd:pfam03176 133 VADLRDAGDRDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGAAQGL-VAILAHILGIGLSTFALNLLVVLLI 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 872 AVGADYNMLLASRLRDESALGVRS--SVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFIIGVGILIDTFVVR 949
Cdd:pfam03176 212 AVGTDYALFLVSRYREELRAGEDReeAVIRAVRGTGKVVTAAGLTVAIAMLALSFARLPVFAQVGPTIAIGVLVDVLAAL 291
|
330 340
....*....|....*....|.
gi 887957230 950 TItVPAMATLLGRASWWPGHP 970
Cdd:pfam03176 292 TL-LPALLALLGRWGLWPPKR 311
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
738-966 |
1.29e-53 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 199.61 E-value: 1.29e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 738 PDGHTVRYFIQTDLNPFSTAAMDQVNTIIDTAKGAqpntsLADASISMSGYPVMLRDIRDYYERDMRLIVAVTVVVVILI 817
Cdd:COG2409 459 TDGDAARLQVVPDGDPDSPEAIDLVDRLRDAAAPA-----LEGAEVLVGGTTAVNIDISDALADDLPLVIPVVLGLIFLL 533
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 818 LMALLRAIVAPLYLVGSVVISYMSAIGLGVVVFQV------FLGQELHWSVPGLAFVVLVAVGADYNMLLASRLRDESA- 890
Cdd:COG2409 534 LLLLFRSVVAPLKAVLTNLLSLGAALGVLVLVFQHgwlllgFTPGPLDSFVPLLLFVILFGLGMDYEVFLVSRIREEYDr 613
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 887957230 891 -LGVRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFIIGVGILIDTFVVRTITVPAMATLLGRASWW 966
Cdd:COG2409 614 gGGTREAVIRGLARTGRVITSAALIMAAVFAAFATSPLVFLKQIGFGLAVGVLLDAFVVRMLLVPALMALLGRWNWW 690
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
31-450 |
1.43e-43 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 170.43 E-value: 1.43e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 31 LPADAPSSVAVRQMAEAFhesGSENILVVLLTDEKG------LGAADE------------------NVYHTLVDRLRNDA 86
Cdd:COG1033 46 LPEDDPSVQAYDEFEEEF---GGDDTVVVAVEGKDDiftpetLEALRElteeleeipgvdsvtsltNVRATEGTEDGLTV 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 87 KDVV-------------MLQDFLTTPPLREVLGSKDGKAWIL--PIGLAGDLGTPKSYHAYTDVERIVKRtVAGTTLTAN 151
Cdd:COG1033 123 EPLIpdelpaspeelaeLREKVLSSPLYVGRLVSPDGKATLIvvTLDPDPLSSDLDRKEVVAEIRAIIAK-YEDPGVEVY 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 152 VTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPVTMLLPLVTIGASLMTAQALV--AGVSLvgglavsNQAI 229
Cdd:COG1033 202 LTGFPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMglLGIPL-------SPLT 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 230 VLLSAMIAGAGTDYAVFLISRYHEYVRLGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAKLGVFSTVGPALAIGI 309
Cdd:COG1033 275 ILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGV 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 310 AVSFLAAVTLLPAILVLAS---PRGWVAPRGERMATFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYDDRKQL 386
Cdd:COG1033 355 LLAFLTSLTLLPALLSLLPrpkPKTRRLKKPPELGRLLAKLARFVLRRPKVILVVALVLAVVSLYGISRLKVEYDFEDYL 434
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 887957230 387 PPSDPSSVGYAAMEHHFSvnQAIPEYLIIHSAHD--LRTPRGLADLEQLAQRVSQIPGVAMVRGVT 450
Cdd:COG1033 435 PEDSPIRQDLDFIEENFG--GSDPLEVVVDTGEPdgLKDPEVLKEIDRLQDYLESLPEVGKVLSLA 498
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
122-331 |
2.06e-24 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 109.95 E-value: 2.06e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 122 DLGTPKSYHAYTDVERIVKRTVAGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPVTMLLPLVT 201
Cdd:COG1033 559 DLDSEEIKALVEEVRAFLAENFPPDGVEVTLTGSAVLFAAINESVIESQIRSLLLALLLIFLLLLLAFRSLRLGLISLIP 638
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 202 IGASLMTAQAL--VAGVSLvgglavsNQAIVLLSAMIAGAGTDYAVFLISRYHEYVRLGEHPERAVQRAMMSVGKVIAAS 279
Cdd:COG1033 639 NLLPILLTFGLmgLLGIPL-------NIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAILFT 711
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 887957230 280 AATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLASPRG 331
Cdd:COG1033 712 SLTLAAGFGVLLFSSFPPLADFGLLLALGLLVALLAALLLLPALLLLLDPRI 763
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
6-336 |
6.02e-24 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 108.31 E-value: 6.02e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 6 VALALVLPMAVPSL---AEMAQRhpvAVLPADAPSSVAVRQMAEAFHEsGSENILVVLLTDEKGLGAADENVYHTLVDRL 82
Cdd:COG2409 366 AAVAVLLALALPALglrLGLPDA---DSLPADSPSRQGYDALAEHFPP-GSNGPLTVVVESDDDLDPADLAALDALAAAL 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 83 RNDaKDVVMLQdfLTTPPLREvlgskDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKRTVAGTTltANVTGPAATVADL 162
Cdd:COG2409 442 AAV-PGVASVQ--PPTRPEGT-----DGDAARLQVVPDGDPDSPEAIDLVDRLRDAAAPALEGAE--VLVGGTTAVNIDI 511
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 163 TDAGARDRASIELAIAVMLLVILMVIYRNPVTMLLPLVTIGASLMTAQALVAGV--SLVGGLAVSNQAI-----VLLSAM 235
Cdd:COG2409 512 SDALADDLPLVIPVVLGLIFLLLLLLFRSVVAPLKAVLTNLLSLGAALGVLVLVfqHGWLLLGFTPGPLdsfvpLLLFVI 591
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 236 IAGAGTDYAVFLISRYHEYVRLGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAKLGVFSTVGPALAIGIAV-SFL 314
Cdd:COG2409 592 LFGLGMDYEVFLVSRIREEYDRGGGTREAVIRGLARTGRVITSAALIMAAVFAAFATSPLVFLKQIGFGLAVGVLLdAFV 671
|
330 340
....*....|....*....|..
gi 887957230 315 AAVTLLPAILVLASPRGWVAPR 336
Cdd:COG2409 672 VRMLLVPALMALLGRWNWWLPR 693
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
99-450 |
4.14e-22 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 102.61 E-value: 4.14e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 99 PPLREVLGSKDGKAWILPIGLAGDLGTPKSYHAYTDVERIVKRTVAGTTLTANVTG-PAATVADLTDAGARDRASIELAI 177
Cdd:TIGR00921 124 PRSKEMFLSKDHTVAIIIVQLKSDADYKQVVPIYNDVERSLERTNPPSGKFLDVTGsPAINYDIEREFGKDMGTTMAISG 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 178 AVMLLViLMVIYRNPVTMLLPLVTIgaslMTAQALVAGvsLVGGLAVSNQAIVLLS-AMIAGAGTDYAVFLISRYHEYVR 256
Cdd:TIGR00921 204 ILVVLV-LLLDFKRWWRPLLPLVII----LFGVAWVLG--IMGWLGIPLYATTLLAvPMLIGVGIDYGIQTLNRYEEERD 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 257 LGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVLAsPRGWVAPR 336
Cdd:TIGR00921 277 IGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTLLVLPALLQSI-DIGREKVK 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 337 GERMA----------TFWrRAGTRIVRRP-KAYLGASLIGLVALASCASLA-HFNYDdrKQLPPSDPSSVGYAAMEHHFS 404
Cdd:TIGR00921 356 KEIIAiggksseieeELS-KVLSITVRHPvPALVAALIITGLGLYGAAGIKpEVNIE--KFIPQDLPSLQARKVIESHMG 432
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 887957230 405 VNQaiPEYLIIHSAHDLRTPRGLADLEQLAQRVSQIPGVAMVRGVT 450
Cdd:TIGR00921 433 GSH--DFATILVKADDVRDPELVRFMDELSRDIKATGVAARVFGAP 476
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
124-326 |
6.63e-21 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 98.76 E-value: 6.63e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 124 GTPKSYHAYtdVERIVKRTVAGTTLTANVTGPAATVADLTDAGARDRASIELAIAVMLLVILMVIYRNPVTMLLPLVTIG 203
Cdd:TIGR00921 525 GEPKVQGRK--ILRDVQHEHPPPGVKVGVTGLPVAFAEMHELVNEGMRRMTIAGAILVLMILLAVFRNPIKAVFPLIAIG 602
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 204 aslmtaqaLVAGVS-LVGGLAV--SNQAIVLLSAMIAGAGTDYAVFLISRYHEyvRLGEH-PERAVQRAMMSVGKVIAAS 279
Cdd:TIGR00921 603 --------SGILWAiGLMGLRGipSFLAMATTISIILGLGMDYSIHLAERYFE--ERKEHgPKEAITHTMERTGPGILFS 672
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 887957230 280 AATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPAILVL 326
Cdd:TIGR00921 673 GLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVVFPALLVL 719
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
732-979 |
1.83e-16 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 84.43 E-value: 1.83e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 732 AQAFISPDGHTVRYFIQTDLNPfSTAAMDQVNTIIDTAKGAQPntslADASISMSGYPVMLRDIRDYYERDMRLIVAVTV 811
Cdd:COG2409 105 AAGLVSEDGKAALVTVTLDGDA-GDEAAEAVDALRDAVAAAPA----PGLTVYVTGPAALAADLNEAFEEDLGRAELITL 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 812 VVVILILMALLRAIVAPLYLVGSVVISYMSAIGLGVVVFQVFlgqELHWSVPGLAFVVLVAVGADYNMLLASRLRDESAL 891
Cdd:COG2409 180 PVALVVLLLVFRSLVAALLPLLTAGLAVGVALGLLALLAAFT---DVSSFAPNLLTMLGLGVGIDYALFLVSRYREELRA 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 892 G--VRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFIIGVGILIDTFVVRTItVPAMATLLGRASWWPGH 969
Cdd:COG2409 257 GedREEAVARAVATAGRAVLFSGLTVAIALLGLLLAGLPFLRSMGPAAAIGVAVAVLAALTL-LPALLALLGRRVFWPRR 335
|
250
....*....|
gi 887957230 970 PWQRCAPEEG 979
Cdd:COG2409 336 PRRRRAAAPE 345
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
152-447 |
4.18e-13 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 73.49 E-value: 4.18e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 152 VTGPAAtVADLTDAGARDRASIELAIA-VMLLVILMVIYRNPVTMLLPLVTIGASLM--TAQALVAgvslVGGLavsNQA 228
Cdd:TIGR03480 253 LTGEVA-LSDEELATVSEGATVAGLLSfVLVLVLLWLALRSPRLVFAVLVTLIVGLIltAAFATLA----VGHL---NLI 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 229 IVLLSAMIAGAGTDYAVFLISRYHEYVRLGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRF-AKLGVfSTVGPALAI 307
Cdd:TIGR03480 325 SVAFAVLFIGLGVDFAIQFSLRYREERFRGGNHREALSVAARRMGAALLLAALATAAGFFAFLPtDYKGV-SELGIIAGT 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 308 GIAVSFLAAVTLLPAILVL-ASPRGWVAPRGERMAtfwrRAGTRIVRRPKAYLGASLIglVALASCASL--AHFNYDdrk 384
Cdd:TIGR03480 404 GMFIALFVTLTVLPALLRLlRPPRRRKPPGYATLA----PLDAFLRRHRRPVLGVTLI--LGIAALALLpqLRFDFN--- 474
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 887957230 385 QLPPSDPSSVGYAAMeHHFSVNQAIPEYLIIHSAHDLRtprglaDLEQLAQRVSQIPGVAMVR 447
Cdd:TIGR03480 475 PLNLQDPKTESVRTF-LELLADPDTSPYSAEVLAPSAP------EARALTERLEALPEVDQVV 530
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
735-962 |
2.29e-12 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 71.04 E-value: 2.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 735 FISPDGHTVRYFIQTDLNPFST-----AAMDQVNTIIDTAKGAqpntslaDASISMSGYPVMLRDIRDYYERDMRLIVAV 809
Cdd:COG1033 154 LVSPDGKATLIVVTLDPDPLSSdldrkEVVAEIRAIIAKYEDP-------GVEVYLTGFPVLRGDIAEAIQSDLAIFFPL 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 810 TVVVVILILMALLRAIVAPLYLVGSVVISYMSAIGlgvvvFQVFLGQELhwSVP-GLAFVVLVAVGADYNMLLASRLRDE 888
Cdd:COG1033 227 ALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLG-----LMGLLGIPL--SPLtILVPPLLLAIGIDYGIHLLNRYREE 299
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 887957230 889 SALG--VRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFIIGVGILIdTFVVRTITVPAMATLLGR 962
Cdd:COG1033 300 RRKGldKREALREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLL-AFLTSLTLLPALLSLLPR 374
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
342-450 |
6.10e-11 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 66.42 E-value: 6.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 342 TFWRRAGTRIVRRPKAYLGASLIGLVALASCASLAHFNYDDRKQLPPSDPSSVGYAAMEHHFSVNQAIpeYLIIHSAHDL 421
Cdd:COG1033 2 RLMERLARFILRHRKLVLLLFLLLTLLLAYGAPKLEVDTDFESLLPEDDPSVQAYDEFEEEFGGDDTV--VVAVEGKDDI 79
|
90 100
....*....|....*....|....*....
gi 887957230 422 RTPRGLADLEQLAQRVSQIPGVAMVRGVT 450
Cdd:COG1033 80 FTPETLEALRELTEELEEIPGVDSVTSLT 108
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
724-959 |
1.83e-09 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 61.78 E-value: 1.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 724 KSEEFKKvaqAFISPDGHTVRyFIQTDLNPfsTAAMDQVNTIIDTAKGAQPNTSLadaSISMSGYPVMLRDIRDYYERDM 803
Cdd:TIGR00921 499 IPEDEEG---GYISGGQIKVA-VIQVQLKQ--GEPKVQGRKILRDVQHEHPPPGV---KVGVTGLPVAFAEMHELVNEGM 569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 804 RLIVAVTVVVVILILMALLRAIVAPlylvgsvvISYMSAIGLGVVVFQVFLGQELHWSVPGLAFVV--LVAVGADYNMLL 881
Cdd:TIGR00921 570 RRMTIAGAILVLMILLAVFRNPIKA--------VFPLIAIGSGILWAIGLMGLRGIPSFLAMATTIsiILGLGMDYSIHL 641
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 887957230 882 ASRLRDE-SALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFIIGVGILIDTFVVRTITvPAMATL 959
Cdd:TIGR00921 642 AERYFEErKEHGPKEAITHTMERTGPGILFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVVF-PALLVL 719
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
92-392 |
2.05e-09 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 61.41 E-value: 2.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 92 LQDFLTTPPLRE-VLGSKDGKaWIL----PIGLAGDLGTPKS-YHAYTDVERIVKRTVAGTTLTanVTGPAAtVADLTDA 165
Cdd:COG4258 170 LQPLGSRPRLRDgVLVSRDGT-WALllaeTRASGFDTDAQQQlVAALRAAFAALNAAFPGAQLL--LTGAGL-FAVAAAQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 166 GARDRASIELAIAVML-LVILMVIYRNPVTMLLPLVTIGASLMTAqalVAGVSLVGGlAVSNQAIVLLSAMIaGAGTDYA 244
Cdd:COG4258 246 QIKHDISTIGLISLLGiLLLLLLVFRSLRPLLLGLLPVAVGALAG---LAAVSLVFG-SVHGITLGFGSSLI-GVAVDYS 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 245 VflisryHEYVRLGEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAK------LGVFStvgpalAIGIAVSFLAAVT 318
Cdd:COG4258 321 L------HYLTHRRAAGEWDPRAALRRIWPTLLLGLLTTVLGYLALLFSPfpglrqLGVFA------AAGLLAAALTTLL 388
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 887957230 319 LLPAILvlaspRGWVAPRGERMATFWRRAGTRIVRRPKAylgasLIGLVALASCASLA-----HFNyDDRKQLPPSDPS 392
Cdd:COG4258 389 WLPLLL-----PRAAPRPPAPALALLARLLARWPRRLRW-----LLALLAVLALASLLglnrlKWN-DDLRALNPVPAA 456
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
723-962 |
2.68e-09 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 61.03 E-value: 2.68e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 723 LKSEEFKKVAQAFISPDGHTVRyfIQTDLNPFSTAAMDQVNTIIDTAkgAQPNTSLADASISMSGYPVMLRDIRDYYERD 802
Cdd:COG1033 531 LLSSPPGDDLSRFVDEDYSAAR--VTVRLKDLDSEEIKALVEEVRAF--LAENFPPDGVEVTLTGSAVLFAAINESVIES 606
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 803 MRLIVAVTVVVVILILMALLRAIVAPLYLVGSVVISymSAIGLGVVvfqVFLGQELHWSVpGLAFVVLVAVGADYNMLLA 882
Cdd:COG1033 607 QIRSLLLALLLIFLLLLLAFRSLRLGLISLIPNLLP--ILLTFGLM---GLLGIPLNIAT-AVVASIALGIGVDYTIHFL 680
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 883 SRLRDESALG--VRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFIIGVGILIdTFVVRTITVPAMATLL 960
Cdd:COG1033 681 SRYREERRKGgdLEEAIRRALRTTGKAILFTSLTLAAGFGVLLFSSFPPLADFGLLLALGLLV-ALLAALLLLPALLLLL 759
|
..
gi 887957230 961 GR 962
Cdd:COG1033 760 DP 761
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
170-368 |
7.71e-07 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 53.18 E-value: 7.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 170 RASIE-----LAIAVmLLVILMVIY--RNPVTMLLPLVTIGASLMTAQAL--VAGVSLvgglavsNqaIVLLSAMIAGAG 240
Cdd:COG0841 327 RASIEevvktLLEAI-LLVVLVVFLflRSWRATLIPAVAIPVSLIGTFAVmyLLGFSL-------N--ILTLFALVLAIG 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 241 --TDYAVFLISRYHEYVRLGEHPERAVQRAMMSVGK-VIAASAATVG----ITFLGMRFAKLgvFSTVGPALAIGIAVSF 313
Cdd:COG0841 397 ivVDDAIVVVENIERHMEEGLSPLEAAIKGAREVAGaVIASTLTLVAvflpLAFMGGITGQL--FRQFALTVAIALLISL 474
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 887957230 314 LAAVTLLPAILVL----------ASPRGWVAPRGERMATFWRRAGTRIVRRPKAYLGASLIGLVA 368
Cdd:COG0841 475 FVALTLTPALCARllkphpkgkkGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLAL 539
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
170-374 |
4.40e-06 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 50.76 E-value: 4.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 170 RASIE-----LAIAVMLLVILMVIY-RNPVTMLLPLVTIGASLMTAQALVA--GVSL----VGGLAVSNQAIVllsamia 237
Cdd:pfam00873 327 RASIEevvktLLEAIVLVILVMFLFlQNWRATLIPAIAIPLSLLGTFAVMKafGFSIntltLGGLVLAIGLVV------- 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 238 gagtDYAVFLISRYHEYVRL-GEHPERAVQRAMMSVGKVIAASAATVGITFLGMRFAKlGV----FSTVGPALAIGIAVS 312
Cdd:pfam00873 400 ----DDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLG-GLtgriFRQFAITIVLAILLS 474
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 887957230 313 FLAAVTLLPAI--LVLA----SPRGWVAPRGERMATFWRRAGTR----IVRRPKAYLGASLIGLVALASCAS 374
Cdd:pfam00873 475 VLVALTLTPALcaTLLKprrePKHGGFFRWFNRMFDRLTRGYAKllakVLRHTAVVLLVALLLVVGSVWLFV 546
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
154-394 |
3.52e-04 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 44.62 E-value: 3.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 154 GPAATVADLTDAGARDRASIE-----LAIAVMLLVILMVIY-RNPVTMLLPLVTIGASLMTaqalVAGVSLVGGLAVSNq 227
Cdd:NF033617 310 PKNIKVNVLYDRTRFIRASIDevestLLEAVALVILVVFLFlRNLRATLIPAVTVPLSLIG----TFAVMYLFGFSINL- 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 228 aIVLLSAMIA-GAGTDYAVFLISRYHEYVRLGEHPERAVQRAMMSVG-KVIAAS----AATVGITFLGMRFAKLgvFSTV 301
Cdd:NF033617 385 -LTLMALVLAiGLVVDDAIVVVENIHRHIEEGESPLEAALKGAREIGfTVIAMTltlvAVYLPILFMGGLTGRL--FREF 461
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 302 GPALAIGIAVSFLAAVTLLPailVLASprgWVAPRGERMATFWRRAGTRIVRRPKAY---LGASL-----IGLVALASCA 373
Cdd:NF033617 462 AVTLAGAVIISGIVALTLTP---MMCS---RLLKANEKPGRFARAVDRFFDGLTARYgrgLKWVLkhrplTLVVALATLA 535
|
250 260
....*....|....*....|.
gi 887957230 374 SLAHFNYDDRKQLPPSDPSSV 394
Cdd:NF033617 536 LLPLLYVFIPKELAPSEDRGV 556
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
176-324 |
5.22e-04 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 44.22 E-value: 5.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 176 AIAVMLLVILmviyRNPVTMLLPLV-TIGASLMTAQALV-AGVSLvgglavsNQAIVLLSAMIAGAGTDYAVFLISRYHE 253
Cdd:TIGR03480 724 AITVLLLLTL----RRVRDVLLVLApLLLAGLLTVAAMVlLGIPF-------NFANIIALPLLLGLGVDFGIYMVHRWRN 792
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 887957230 254 YVRLGEHPERAVQRAMMsvgkviaASAATVGITFLGMRFAK-LGVFStVGPALAIGIAVSFLAAVTLLPAIL 324
Cdd:TIGR03480 793 GVDSGNLLQSSTARAVF-------FSALTTATAFGSLAVSShPGTAS-MGILLSLGLGLTLLCTLIFLPALL 856
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
866-960 |
6.74e-04 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 43.83 E-value: 6.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 866 AFVVL-VAVGADYNMLLASRLRDE--SALGVRSSVIRTVRCTGGVITAAGLIFAASMSGLLFSSIGTVVQGGFIIGVGIL 942
Cdd:TIGR03480 327 AFAVLfIGLGVDFAIQFSLRYREErfRGGNHREALSVAARRMGAALLLAALATAAGFFAFLPTDYKGVSELGIIAGTGMF 406
|
90
....*....|....*....
gi 887957230 943 IDTFVvrTITV-PAMATLL 960
Cdd:TIGR03480 407 IALFV--TLTVlPALLRLL 423
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
175-322 |
1.62e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 42.53 E-value: 1.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 887957230 175 LAIAVMLLVILMVIYRNPVTMLLPLVTIGASLMTAqalvagvslVGGLAVSNQAIVLLSAM----IAGAGTDYAVFLISr 250
Cdd:COG4258 646 LLALLLILLLLLLRLRSLRRALRVLLPPLLAVLLT---------LAILGLLGIPLNLFHLIalllVLGIGIDYALFFTE- 715
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 887957230 251 yheyvrlGEHPERAVQRAMMSvgkvIAASAATVGITFLGMRFAKLGVFSTVGPALAIGIAVSFLAAVTLLPA 322
Cdd:COG4258 716 -------GLLDKGELARTLLS----ILLAALTTLLGFGLLAFSSTPALRSFGLTVLLGILLALLLAPLLAPR 776
|
|
| |
