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Conserved domains on  [gi|801427870|emb|CFG54037|]
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sulfotransferase [Mycobacterium tuberculosis]

Protein Classification

Stf0 sulfotransferase family protein( domain architecture ID 10557204)

Stf0 sulfotransferase family protein similar to Mycobacterial sulfotransferase, Stf0, that initiates sulfolipid-1 (SL-1) biosynthesis: Stf0 transfers the sulfuryl group from PAPS to trehalose to form T2S, the core disaccharide of SL-1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sulphotransf pfam09037
Stf0 sulphotransferase; Members of this family are essential for the biosynthesis of ...
 8-259 2.70e-128

Stf0 sulphotransferase; Members of this family are essential for the biosynthesis of sulpholipid-1 in prokaryotes. They adopt a structure that belongs to the sulphotransferase superfamily, consisting of a single domain with a core four-stranded parallel beta-sheet flanked by alpha-helices.


:

Pssm-ID: 430381  Cd Length: 244  Bit Score: 363.78  E-value: 2.70e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870    8 YLVLATQRSGSTLLVESLRATGCAGEPQEFFQylpstgmAPQPREWFAGVDDdtilqlldPLDPGTPDTATPVAWREHVR 87
Cdd:pfam09037   2 YLICATPRSGSTLLCESLRATGVAGEPDSFFQ-------APQPREWFAYVGL--------PLDRGTPDTAFARAWREAAL 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870   88 TSGRTPNGVWGGKLMWNQTALLQQRAAQL-PDRSGDGLRaaIRDVIGNePVFVHVHRPDVVSQAVSFWRAVQTQVWRGHP 166
Cdd:pfam09037  67 TVGRTPNGVFGLRLMWNQTGLLLQRLDHLyPDLSGDGLR--IEDAFGR-TLYIHLHRPDKVSQAVSFWRAVQSGLWHGAP 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870  167 DPKRDSQ------AVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPA-- 238
Cdd:pfam09037 144 DGTEDERlspprdPTYDAGAIAHQVRALEAQEEGWRDWFAEEQIEPLRVDYPVLWRNPTEVVSAILRALGQDPRLAPDgp 223

                         250       260
                  ....*....|....*....|.
gi 801427870  239 PMLERQANQRSDEWVDRYRAE 259
Cdd:pfam09037 224 PVLEKLADERSDEWVDRYRAD 244
 
Name Accession Description Interval E-value
Sulphotransf pfam09037
Stf0 sulphotransferase; Members of this family are essential for the biosynthesis of ...
 8-259 2.70e-128

Stf0 sulphotransferase; Members of this family are essential for the biosynthesis of sulpholipid-1 in prokaryotes. They adopt a structure that belongs to the sulphotransferase superfamily, consisting of a single domain with a core four-stranded parallel beta-sheet flanked by alpha-helices.


Pssm-ID: 430381  Cd Length: 244  Bit Score: 363.78  E-value: 2.70e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870    8 YLVLATQRSGSTLLVESLRATGCAGEPQEFFQylpstgmAPQPREWFAGVDDdtilqlldPLDPGTPDTATPVAWREHVR 87
Cdd:pfam09037   2 YLICATPRSGSTLLCESLRATGVAGEPDSFFQ-------APQPREWFAYVGL--------PLDRGTPDTAFARAWREAAL 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870   88 TSGRTPNGVWGGKLMWNQTALLQQRAAQL-PDRSGDGLRaaIRDVIGNePVFVHVHRPDVVSQAVSFWRAVQTQVWRGHP 166
Cdd:pfam09037  67 TVGRTPNGVFGLRLMWNQTGLLLQRLDHLyPDLSGDGLR--IEDAFGR-TLYIHLHRPDKVSQAVSFWRAVQSGLWHGAP 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870  167 DPKRDSQ------AVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPA-- 238
Cdd:pfam09037 144 DGTEDERlspprdPTYDAGAIAHQVRALEAQEEGWRDWFAEEQIEPLRVDYPVLWRNPTEVVSAILRALGQDPRLAPDgp 223

                         250       260
                  ....*....|....*....|.
gi 801427870  239 PMLERQANQRSDEWVDRYRAE 259
Cdd:pfam09037 224 PVLEKLADERSDEWVDRYRAD 244
LpsS COG4424
LPS sulfotransferase NodH [Cell wall/membrane/envelope biogenesis];
2-267 3.63e-78

LPS sulfotransferase NodH [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443539  Cd Length: 238  Bit Score: 236.45  E-value: 3.63e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870   2 SRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQylpstgmAPQPREWFAGVDDDtilqlldpldpgtPDTATPVA 81
Cdd:COG4424    3 TRPFRSYVICATPRSGSTLLCELLNATGVAGCPGEYFN-------PPFIPEWARGFLLG-------------DRDRDPDE 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870  82 WREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDglraairdvignePVFVHVHRPDVVSQAVSFWRAVQTQV 161
Cdd:COG4424   63 YLRAIRRAGTTPNGVFGFKLFWDQLPRLLQRALRLLAAFPD-------------LKFIHLTRRDKLAQAVSLVIAQQTGQ 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870 162 WRGHPD--PKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPA- 238
Cdd:COG4424  130 WHSDADdaLAPTAPPEYDAEEIARLLEALQDFEARWEAWFARTGITPLEITYEDLAADPVEVLNRVLDFLGVDPPLAPLr 209

                        250       260
                 ....*....|....*....|....*....
gi 801427870 239 PMLERQANQRSDEWVDRYRAEAPRLGLPT 267
Cdd:COG4424  210 PALKKQADEPSDEWVARFREEAEALAALD 238
 
Name Accession Description Interval E-value
Sulphotransf pfam09037
Stf0 sulphotransferase; Members of this family are essential for the biosynthesis of ...
 8-259 2.70e-128

Stf0 sulphotransferase; Members of this family are essential for the biosynthesis of sulpholipid-1 in prokaryotes. They adopt a structure that belongs to the sulphotransferase superfamily, consisting of a single domain with a core four-stranded parallel beta-sheet flanked by alpha-helices.


Pssm-ID: 430381  Cd Length: 244  Bit Score: 363.78  E-value: 2.70e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870    8 YLVLATQRSGSTLLVESLRATGCAGEPQEFFQylpstgmAPQPREWFAGVDDdtilqlldPLDPGTPDTATPVAWREHVR 87
Cdd:pfam09037   2 YLICATPRSGSTLLCESLRATGVAGEPDSFFQ-------APQPREWFAYVGL--------PLDRGTPDTAFARAWREAAL 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870   88 TSGRTPNGVWGGKLMWNQTALLQQRAAQL-PDRSGDGLRaaIRDVIGNePVFVHVHRPDVVSQAVSFWRAVQTQVWRGHP 166
Cdd:pfam09037  67 TVGRTPNGVFGLRLMWNQTGLLLQRLDHLyPDLSGDGLR--IEDAFGR-TLYIHLHRPDKVSQAVSFWRAVQSGLWHGAP 143

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870  167 DPKRDSQ------AVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPA-- 238
Cdd:pfam09037 144 DGTEDERlspprdPTYDAGAIAHQVRALEAQEEGWRDWFAEEQIEPLRVDYPVLWRNPTEVVSAILRALGQDPRLAPDgp 223

                         250       260
                  ....*....|....*....|.
gi 801427870  239 PMLERQANQRSDEWVDRYRAE 259
Cdd:pfam09037 224 PVLEKLADERSDEWVDRYRAD 244
LpsS COG4424
LPS sulfotransferase NodH [Cell wall/membrane/envelope biogenesis];
2-267 3.63e-78

LPS sulfotransferase NodH [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443539  Cd Length: 238  Bit Score: 236.45  E-value: 3.63e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870   2 SRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQylpstgmAPQPREWFAGVDDDtilqlldpldpgtPDTATPVA 81
Cdd:COG4424    3 TRPFRSYVICATPRSGSTLLCELLNATGVAGCPGEYFN-------PPFIPEWARGFLLG-------------DRDRDPDE 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870  82 WREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDglraairdvignePVFVHVHRPDVVSQAVSFWRAVQTQV 161
Cdd:COG4424   63 YLRAIRRAGTTPNGVFGFKLFWDQLPRLLQRALRLLAAFPD-------------LKFIHLTRRDKLAQAVSLVIAQQTGQ 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 801427870 162 WRGHPD--PKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPA- 238
Cdd:COG4424  130 WHSDADdaLAPTAPPEYDAEEIARLLEALQDFEARWEAWFARTGITPLEITYEDLAADPVEVLNRVLDFLGVDPPLAPLr 209

                        250       260
                 ....*....|....*....|....*....
gi 801427870 239 PMLERQANQRSDEWVDRYRAEAPRLGLPT 267
Cdd:COG4424  210 PALKKQADEPSDEWVARFREEAEALAALD 238
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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