|
Name |
Accession |
Description |
Interval |
E-value |
| cas1 |
TIGR00287 |
CRISPR-associated endonuclease Cas1; This model identifies CRISPR-associated protein Cas1, the ... |
3-325 |
7.94e-116 |
|
CRISPR-associated endonuclease Cas1; This model identifies CRISPR-associated protein Cas1, the most universal CRISPR system protein. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Cas1 is a metal-dependent DNA-specific endonuclease.
Pssm-ID: 272998 Cd Length: 323 Bit Score: 338.16 E-value: 7.94e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 3 QLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTP-DV 81
Cdd:TIGR00287 1 TLYVLEYGSYLSRKGNTLVVEKEGKKKWNIPVANVDCIVLFGGVSISSAAIRLLAKRGIDIVFFGGDGNYVGRLSPQeSG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 82 SYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRT----MKHSLAWVDrsgSLAELNGFEGN 157
Cdd:TIGR00287 81 STVELRLAQVKAYLDEEKRLKLAKEFVSGKIANQAALLKYLTRRREDLRSYLEeyesLMKELASAD---SIEELMGIEGN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 158 AAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237
Cdd:TIGR00287 158 AARAYYAALAQLLPDEFGFNGRSKRPPKDPFNALLSYGYSLLYSNVLTAIYIAGLDPYIGFLHTDRSGRPSLVLDLMEEF 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 238 RAPIIDDTVLRLIADGVVDTRAFSKNSdtGAVFATREATRSIARAFGNRIARTATYIKGDPhRYTFQYALDLQLQSLVRV 317
Cdd:TIGR00287 238 KPQIVDRLVFSLINRNIITEEDFEKIS--NGVYLGEEGRKKFLQAFEERLQTTVTHPGLNR-RVSYLDIIILQARKLAKA 314
|
....*...
gi 800309297 318 IEAGHPAR 325
Cdd:TIGR00287 315 LRGEERYR 322
|
|
| Cas1_I-II-III |
cd09636 |
CRISPR/Cas system-associated protein Cas1; CRISPR (Clustered Regularly Interspaced Short ... |
4-260 |
6.10e-99 |
|
CRISPR/Cas system-associated protein Cas1; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain
Pssm-ID: 187767 Cd Length: 260 Bit Score: 292.66 E-value: 6.10e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 4 LYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTP-DVS 82
Cdd:cd09636 1 LYVLEYGSYLSRKGNTLVVEKEGELKKNIPVANVDCIVIFGGVSISSAAIRELAKRGIDIVFLGGDGNYLGRLYPPePGS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 83 YAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRTMK--HSLAWVDRSGSLAELNGFEGNAAK 160
Cdd:cd09636 81 SVFTRRAQYKAYLNPAKRLKLAREFVEGKLANQAALLRYLTRRREDLKSELAEYiaELLKELDNANSIEELMGIEGNAAR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 161 AYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 240
Cdd:cd09636 161 AYYAALAQLLPDEFGFNGRSRRPPKDPFNALLSYGYSLLYSNVLTAIYIAGLDPYIGFLHTDRSGRPSLVLDLMEEFRPQ 240
|
250 260
....*....|....*....|
gi 800309297 241 IIDDTVLRLIADGVVDTRAF 260
Cdd:cd09636 241 IVDRLVFSLINRGIITPEDF 260
|
|
| Cas_Cas1 |
pfam01867 |
CRISPR associated protein Cas1; Clustered regularly interspaced short palindromic repeats ... |
4-283 |
1.78e-91 |
|
CRISPR associated protein Cas1; Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.
Pssm-ID: 460366 Cd Length: 283 Bit Score: 274.33 E-value: 1.78e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 4 LYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSY 83
Cdd:pfam01867 1 LYVTTPGAYLSRKGETLVVEKEGEEKKRIPLEDVEQIVIFGNVSISTAALRLLAERGIPVHFLSYYGRYLGRLYPEVSGN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 84 APRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR---AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAK 160
Cdd:pfam01867 81 VLLRRAQYRAYDDEEKRLELARSFVAGKLRNQRTVLRrynRDRKDEALEEAIEELEELLKKLERADSIDELRGIEGNAAR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 161 AYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 240
Cdd:pfam01867 161 AYFSAFDELLPKEFGFEGRSRRPPLDPVNALLSFGYTLLYSDVLSALEAVGLDPYIGFLHEDRPGRPSLALDLMEEFRPV 240
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 800309297 241 IIDDTVLRLIADGVVDTRAFSKNSdtGAVFATREATRSIARAF 283
Cdd:pfam01867 241 IVDRLVLSLINRGQITPKDFEKRE--NGVLLNDEGRKKFLKAY 281
|
|
| Cas1 |
COG1518 |
CRISPR-Cas system-associated integrase Cas1 [Defense mechanisms]; CRISPR-Cas system-associated ... |
4-319 |
4.69e-91 |
|
CRISPR-Cas system-associated integrase Cas1 [Defense mechanisms]; CRISPR-Cas system-associated integrase Cas1 is part of the Pathway/BioSystem: CRISPR-Cas system
Pssm-ID: 441127 Cd Length: 329 Bit Score: 275.16 E-value: 4.69e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 4 LYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPD-VS 82
Cdd:COG1518 2 LYITEPGAYLSRKGNTLVVEKEDEEKKRVPLEDIEQIVLFGEVSLSTALLRFLAENGIPVHFLDYYGRYLGRLLPREsGG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 83 YAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR--AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAK 160
Cdd:COG1518 82 NVLLRRAQYQAYLDEEKRLALARSIVRGKIRNQRAVLRryGRRRKEDLEEAIERLEELLKRLEEADSIDELRGIEGNAAR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 161 AYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 240
Cdd:COG1518 162 IYFSALDGLLPEDFRFEGRSRRPPRDPVNALLSFGYTLLYSDVLSAIYAAGLDPYIGFLHEPRPGRPSLALDLMEEFRPI 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 800309297 241 IIDDTVLRLIADGVVDTRAFSKnsDTGAVFATREATRSIARAFGNRIARTATYIKGDpHRYTFQYALDLQLQSLVRVIE 319
Cdd:COG1518 242 LVDRLVLSLINRGQITPKDFEK--ELGGVLLTEEGRKKFLEAFEERLQETIKHPFLG-RKVSYRRLIRLQARKLAKHLR 317
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| cas1 |
TIGR00287 |
CRISPR-associated endonuclease Cas1; This model identifies CRISPR-associated protein Cas1, the ... |
3-325 |
7.94e-116 |
|
CRISPR-associated endonuclease Cas1; This model identifies CRISPR-associated protein Cas1, the most universal CRISPR system protein. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Cas1 is a metal-dependent DNA-specific endonuclease.
Pssm-ID: 272998 Cd Length: 323 Bit Score: 338.16 E-value: 7.94e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 3 QLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTP-DV 81
Cdd:TIGR00287 1 TLYVLEYGSYLSRKGNTLVVEKEGKKKWNIPVANVDCIVLFGGVSISSAAIRLLAKRGIDIVFFGGDGNYVGRLSPQeSG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 82 SYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRT----MKHSLAWVDrsgSLAELNGFEGN 157
Cdd:TIGR00287 81 STVELRLAQVKAYLDEEKRLKLAKEFVSGKIANQAALLKYLTRRREDLRSYLEeyesLMKELASAD---SIEELMGIEGN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 158 AAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237
Cdd:TIGR00287 158 AARAYYAALAQLLPDEFGFNGRSKRPPKDPFNALLSYGYSLLYSNVLTAIYIAGLDPYIGFLHTDRSGRPSLVLDLMEEF 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 238 RAPIIDDTVLRLIADGVVDTRAFSKNSdtGAVFATREATRSIARAFGNRIARTATYIKGDPhRYTFQYALDLQLQSLVRV 317
Cdd:TIGR00287 238 KPQIVDRLVFSLINRNIITEEDFEKIS--NGVYLGEEGRKKFLQAFEERLQTTVTHPGLNR-RVSYLDIIILQARKLAKA 314
|
....*...
gi 800309297 318 IEAGHPAR 325
Cdd:TIGR00287 315 LRGEERYR 322
|
|
| Cas1_I-II-III |
cd09636 |
CRISPR/Cas system-associated protein Cas1; CRISPR (Clustered Regularly Interspaced Short ... |
4-260 |
6.10e-99 |
|
CRISPR/Cas system-associated protein Cas1; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain
Pssm-ID: 187767 Cd Length: 260 Bit Score: 292.66 E-value: 6.10e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 4 LYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTP-DVS 82
Cdd:cd09636 1 LYVLEYGSYLSRKGNTLVVEKEGELKKNIPVANVDCIVIFGGVSISSAAIRELAKRGIDIVFLGGDGNYLGRLYPPePGS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 83 YAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIRTMK--HSLAWVDRSGSLAELNGFEGNAAK 160
Cdd:cd09636 81 SVFTRRAQYKAYLNPAKRLKLAREFVEGKLANQAALLRYLTRRREDLKSELAEYiaELLKELDNANSIEELMGIEGNAAR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 161 AYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 240
Cdd:cd09636 161 AYYAALAQLLPDEFGFNGRSRRPPKDPFNALLSYGYSLLYSNVLTAIYIAGLDPYIGFLHTDRSGRPSLVLDLMEEFRPQ 240
|
250 260
....*....|....*....|
gi 800309297 241 IIDDTVLRLIADGVVDTRAF 260
Cdd:cd09636 241 IVDRLVFSLINRGIITPEDF 260
|
|
| Cas1_I-II-III |
cd09634 |
CRISPR/Cas system-associated protein Cas1; CRISPR (Clustered Regularly Interspaced Short ... |
4-319 |
3.58e-96 |
|
CRISPR/Cas system-associated protein Cas1; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain
Pssm-ID: 187766 Cd Length: 317 Bit Score: 287.59 E-value: 3.58e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 4 LYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPD-VS 82
Cdd:cd09634 3 LYITTPGAYLSRKGNRLVVEKEDEKKKRIPLEDIDSIVIFGNVSISTAALRLLAENGIPVHFLDYYGRYLGRLYPPEgGR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 83 YAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI-RAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKA 161
Cdd:cd09634 83 SVLLRRAQYEAYLDPEKRLELAREIVRGKIRNQRRVLkRYARDGKELLLALAELEELLEKLDKAKSIEELRGIEGNAAKI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 162 YFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPI 241
Cdd:cd09634 163 YFEALFQLLPKEFRFEGRSRRPPKDPVNALLSYGYSLLYSAVLSAIVAAGLDPYIGFLHEDRPGRPSLALDLMEEFRPII 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 800309297 242 IDDTVLRLIADGVVDTRAFSKnsDTGAVFATREATRSIARAFGNRIARTATYIKGdpHRYTFQYALDLQLQSLVRVIE 319
Cdd:cd09634 243 VDRLVLSLINKGQIKKKDFEK--ELGGVLLTEEGRKKLIEALEERLKETIKHYLG--RKVSYRRLIRLQAYKLAKHLR 316
|
|
| Cas_Cas1 |
pfam01867 |
CRISPR associated protein Cas1; Clustered regularly interspaced short palindromic repeats ... |
4-283 |
1.78e-91 |
|
CRISPR associated protein Cas1; Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.
Pssm-ID: 460366 Cd Length: 283 Bit Score: 274.33 E-value: 1.78e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 4 LYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSY 83
Cdd:pfam01867 1 LYVTTPGAYLSRKGETLVVEKEGEEKKRIPLEDVEQIVIFGNVSISTAALRLLAERGIPVHFLSYYGRYLGRLYPEVSGN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 84 APRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR---AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAK 160
Cdd:pfam01867 81 VLLRRAQYRAYDDEEKRLELARSFVAGKLRNQRTVLRrynRDRKDEALEEAIEELEELLKKLERADSIDELRGIEGNAAR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 161 AYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 240
Cdd:pfam01867 161 AYFSAFDELLPKEFGFEGRSRRPPLDPVNALLSFGYTLLYSDVLSALEAVGLDPYIGFLHEDRPGRPSLALDLMEEFRPV 240
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 800309297 241 IIDDTVLRLIADGVVDTRAFSKNSdtGAVFATREATRSIARAF 283
Cdd:pfam01867 241 IVDRLVLSLINRGQITPKDFEKRE--NGVLLNDEGRKKFLKAY 281
|
|
| Cas1 |
COG1518 |
CRISPR-Cas system-associated integrase Cas1 [Defense mechanisms]; CRISPR-Cas system-associated ... |
4-319 |
4.69e-91 |
|
CRISPR-Cas system-associated integrase Cas1 [Defense mechanisms]; CRISPR-Cas system-associated integrase Cas1 is part of the Pathway/BioSystem: CRISPR-Cas system
Pssm-ID: 441127 Cd Length: 329 Bit Score: 275.16 E-value: 4.69e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 4 LYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPD-VS 82
Cdd:COG1518 2 LYITEPGAYLSRKGNTLVVEKEDEEKKRVPLEDIEQIVLFGEVSLSTALLRFLAENGIPVHFLDYYGRYLGRLLPREsGG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 83 YAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR--AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAK 160
Cdd:COG1518 82 NVLLRRAQYQAYLDEEKRLALARSIVRGKIRNQRAVLRryGRRRKEDLEEAIERLEELLKRLEEADSIDELRGIEGNAAR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 161 AYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 240
Cdd:COG1518 162 IYFSALDGLLPEDFRFEGRSRRPPRDPVNALLSFGYTLLYSDVLSAIYAAGLDPYIGFLHEPRPGRPSLALDLMEEFRPI 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 800309297 241 IIDDTVLRLIADGVVDTRAFSKnsDTGAVFATREATRSIARAFGNRIARTATYIKGDpHRYTFQYALDLQLQSLVRVIE 319
Cdd:COG1518 242 LVDRLVLSLINRGQITPKDFEK--ELGGVLLTEEGRKKFLEAFEERLQETIKHPFLG-RKVSYRRLIRLQARKLAKHLR 317
|
|
| Cas1_I-C |
cd09721 |
CRISPR/Cas system-associated protein Cas1; CRISPR (Clustered Regularly Interspaced Short ... |
20-286 |
1.13e-54 |
|
CRISPR/Cas system-associated protein Cas1; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain
Pssm-ID: 187852 Cd Length: 338 Bit Score: 182.05 E-value: 1.13e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 20 VIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPdVSYAPRLRQQVHR-TDDPA 98
Cdd:cd09721 21 VVVEVEGEKKARVPLHHLGGIVCFGNVGLSPFLMGRCAEDGISLVFLTENGRFLARVEGP-VSGNVLLRRAQYRaADDPE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 99 FCLSLSKRIVSRKILNQ-QALIRA---HTSGQDVA---ESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVP 171
Cdd:cd09721 100 RSLAIARSIVAGKIRNArQVLLRAardHGEEDDRAaleAAADRLAVALRRLQRADDLDELRGIEGEAARLYFAVFDHLLR 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 172 QE---FAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLR 248
Cdd:cd09721 180 QDapaFRFDGRSRRPPLDPVNALLSFLYTLLTHDCRSALEGVGLDPAVGFLHRDRPGRPSLALDLMEEFRAVLADRLALS 259
|
250 260 270
....*....|....*....|....*....|....*...
gi 800309297 249 LIADGVVDTRAFSKnSDTGAVFATREATRSIARAFGNR 286
Cdd:cd09721 260 LINRGQLTAKDFEV-REGGAVLLTDDARKTVLVAYQER 296
|
|
| cas1_DVULG |
TIGR03640 |
CRISPR-associated endonuclease Cas1, subtype I-C/DVULG; The CRISPR-associated protein Cas1 is ... |
20-286 |
1.83e-54 |
|
CRISPR-associated endonuclease Cas1, subtype I-C/DVULG; The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.
Pssm-ID: 188360 Cd Length: 340 Bit Score: 181.28 E-value: 1.83e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 20 VIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPdVSYAPRLRQQVHR-TDDPA 98
Cdd:TIGR03640 22 VVVEVEGEKKARVPLHHLGGIVCFGNVGLSPFLMGRCAEDGISLVFLTENGRFLARVEGP-VSGNVLLRRAQYRaADDPE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 99 FCLSLSKRIVSRKILNQQALI----RAHTSGQDVA---ESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVP 171
Cdd:TIGR03640 101 RSLAIARSIVAGKIRNARQVLlraaRDHGEEDDAAaleAAADRLAVALRRLQRADDLDSLRGIEGEAARLYFAVFDHLLR 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 172 QE---FAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLR 248
Cdd:TIGR03640 181 QDrpaFRFDGRSRRPPLDPVNALLSFLYTLLTHDCRSALEGVGLDPAVGFLHRDRPGRPSLALDLMEEFRAVLADRLALS 260
|
250 260 270
....*....|....*....|....*....|....*...
gi 800309297 249 LIADGVVDTRAFSKnSDTGAVFATREATRSIARAFGNR 286
Cdd:TIGR03640 261 LINRGQLTAKDFEV-REGGAVLLTDDARKTVLVAYQER 297
|
|
| cas1_CYANO |
TIGR04093 |
CRISPR-associated endonuclease Cas1, subtype CYANO; The CRISPR-associated protein Cas1 is ... |
4-286 |
1.83e-53 |
|
CRISPR-associated endonuclease Cas1, subtype CYANO; The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes a clade of Cas1 limited to the CYANO subtype of CRISPR/Cas system and most often the type found there.
Pssm-ID: 274976 Cd Length: 323 Bit Score: 178.39 E-value: 1.83e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 4 LYVSDSVSRISFADGRVIVwSEELGESQ---YPIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRIsTPD 80
Cdd:TIGR04093 3 LYITQPDAKISKDDGRIIV-VDSDGEEKvasFPLIKVETIVVFGEATLTTPALAHLLERGIVLHYLTRFGKYFGSL-VPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 81 VSYAPRLRQQVHRT-DDPAFCLSLSKRIVSRKILNQQALIRAHTSGQDVAESIrtmkhsLAWVDRSGSLAELNGFEGNAA 159
Cdd:TIGR04093 81 LTRNTILRVAQHQAhISPQQRLAIAREIVRGKLRNSRTMLYRRGRKQTKIPEL------EKPVDDKNSLDSLRGLEGEAA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 160 KAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRA 239
Cdd:TIGR04093 155 AIYFGCLSDLLPDEWSFHGRTRRPPTDPVNALLSLGYALLRTQVLSALRIVGLDPYIGFLHVDRHGRPALALDLMEEFRP 234
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 800309297 240 PIIDDTVLRLIADGVVDTRAFskNSDTGAVFATREATRSIARAFGNR 286
Cdd:TIGR04093 235 IIVDAVVLRLINRKMLKPKDF--QEEPGAVRLKDEAFKLFLGKFEEK 279
|
|
| Cas1_I-B |
cd09722 |
CRISPR/Cas system-associated protein Cas1; CRISPR (Clustered Regularly Interspaced Short ... |
33-316 |
4.16e-33 |
|
CRISPR/Cas system-associated protein Cas1; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain
Pssm-ID: 187853 Cd Length: 320 Bit Score: 124.63 E-value: 4.16e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 33 PIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGristpdvSYAPR--------LRQQVHRTDDPAFCLSLS 104
Cdd:cd09722 29 PVENIDEIYVFGEVSLNSKALSFLSKKGIPIHFFNYYGYYSG-------SFYPReslnsgylIVKQVEHYLDSEKRLELA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 105 KRIVSRKILN-QQALIRAHTSGQDVAESIRTMKHSLAWVDrsgSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRP 183
Cdd:cd09722 102 RSFVEGAAHNmRRVLKYYKDRGDDLDDYLDEIEEQKESAN---SINELMGVEGNIRKTYYSAFDEILKDEFRFEKRTRRP 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 184 PLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKn 263
Cdd:cd09722 179 PKNELNALISFGNSLLYTTVLSEIYKTHLNPTISYLHEPSERRFSLALDIAEIFKPIIVDRLIFRLVNKKIIKEKHFEK- 257
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 800309297 264 sDTGAVFATREATRSIARAFGNRIARTatyIKgdpHR-----YTFQYALDLQLQSLVR 316
Cdd:cd09722 258 -DLNGVLLNEEGRKKFVKEFEEKLKTT---IK---HRklkrkVSYRRLIRLELYKLIK 308
|
|
| cas1_HMARI |
TIGR03641 |
CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP; The CRISPR-associated protein ... |
33-316 |
1.96e-32 |
|
CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP; The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.
Pssm-ID: 274695 Cd Length: 320 Bit Score: 123.10 E-value: 1.96e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 33 PIETLDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGristpdvSYAPR--------LRQQVHRTDDPAFCLSLS 104
Cdd:TIGR03641 30 PVENIDEIYVFGEVSLNSKALSFLSKKGIPIHFFNYYGYYSG-------SFYPReslnsgylIVKQVEHYLDSEKRLELA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 105 KRIVSRKILNQQALIRAHTSGQDVAESIRTMKHSLAwvdRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRSTRPP 184
Cdd:TIGR03641 103 RSFVEGAAHNMRRVLKYYKKRGKDLDKIEAYLESLK---EAKSINELMGVEGNIRKTYYSAFDEILPKGFRFEKRTRRPP 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 185 LDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKns 264
Cdd:TIGR03641 180 KNELNALISFGNSLLYTTVLSEIYKTHLNPTISYLHEPSERRFSLALDIAEIFKPIIVDRLIFRLVNKKIIKEKHFEK-- 257
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 800309297 265 DTGAVFATREATRSIARAFGNRIARTatyIKgdpHR-----YTFQYALDLQLQSLVR 316
Cdd:TIGR03641 258 DLNGVLLNEEGRKKFIKEFEEKLKTT---IK---HRklkrkVSYRRLIRLELYKLIK 308
|
|
| cas1_NMENI |
TIGR03639 |
CRISPR-associated endonuclease Cas1, subtype II/NMENI; The CRISPR-associated protein Cas1 is ... |
4-250 |
1.31e-17 |
|
CRISPR-associated endonuclease Cas1, subtype II/NMENI; The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.
Pssm-ID: 274694 Cd Length: 278 Bit Score: 81.53 E-value: 1.31e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 4 LYVSDSvSRISFADGRVIVWSEElGESQYPIETLDGItLFGRP--TMTTPFIVEMLkrERDIQLFTTDghyqgRISTPDV 81
Cdd:TIGR03639 4 VEISNH-EKLSLKLNQLVIKKDG-EEVTLPLEDIDVI-LIENPqiTISSALLSALA--ENNIALIFCD-----EKHLPVG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 82 SYAP---------RLRQQVHRTDDpaFCLSLSKRIVSRKILNQQALIrAHTSGQDVAESIRTMKHSLawvdRSGslaELN 152
Cdd:TIGR03639 74 QLLPfyghhrslkRLKLQIDWSLP--LKKQLWQKIIKQKILNQAFVL-EKLNLDEDSEKLENLANKV----ESG---DKT 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 153 GFEGNAAKAYFTALghlvpqeFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASD 232
Cdd:TIGR03639 144 NREAHAAKLYFKTL-------FGKDFSRDDDGEDPINAALNYGYAILRSAVARALVKSGLLPRLGIFHKSEYNPFNLADD 216
|
250
....*....|....*...
gi 800309297 233 LMEVWRaPIIDDTVLRLI 250
Cdd:TIGR03639 217 LMEPFR-PLVDYLVYELL 233
|
|
| Cas1_II |
cd09720 |
CRISPR/Cas system-associated protein Cas1; CRISPR (Clustered Regularly Interspaced Short ... |
4-256 |
9.09e-17 |
|
CRISPR/Cas system-associated protein Cas1; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.
Pssm-ID: 187851 Cd Length: 275 Bit Score: 78.83 E-value: 9.09e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 4 LYVSDSvSRISFADGRVIVWSEElGESQYPIETLDGItLFGRP--TMTTPFIVEMLkrERDIQLFTTDGHYQgristPDV 81
Cdd:cd09720 4 VEISNH-EKLSLKLNQLVVKKDN-GRITLPLEDIDVI-LIENPqvTISAALLNALA--ENNIALIFCDEKHL-----PVG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 82 SYAP---------RLRQQVHRTDDpaFCLSLSKRIVSRKILNQQALIrAHTSGQDVAESIRTMKHSLawvdRSGslaELN 152
Cdd:cd09720 74 QLLPfyghhrslkRLKLQIKWSDP--FKKRLWQKIIKQKILNQAFVL-EKLGIFEDAEKLKNLANKV----ESG---DKT 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 800309297 153 GFEGNAAKAYFTALghlVPQEFAfqgRSTRppLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASD 232
Cdd:cd09720 144 NREAHAAKLYFKTL---FGEDFS---RDDN--GDPINAALNYGYSILRSAVARALVKAGLLPRLGIFHKSEYNPFNLADD 215
|
250 260
....*....|....*....|....
gi 800309297 233 LMEVWRaPIIDDTVLRLIADGVVD 256
Cdd:cd09720 216 LMEPFR-PLVDYLVYELLFESREE 238
|
|
|