|
Name |
Accession |
Description |
Interval |
E-value |
| MurF |
COG0770 |
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
3-461 |
0e+00 |
|
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl pentapeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440533 [Multi-domain] Cd Length: 451 Bit Score: 578.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 3 PMTVRELLTATGGRLLGEEAVaerTITGVETDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTEEVPQVLLPgk 82
Cdd:COG0770 2 LLTLAEIAEATGGRLIGDPDL---VVTGVSTDSRKIKPGDLFVALKGERFDGHDFVAQALAKGAAAALVSRPLPADLP-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 83 fYIQVEDTMLAIGQVARAYREKFPIPVIGITGSVGKTTTKDMVASVLGQKFRVLKTEGNFNNELGLPLTLFRLTAQHQIC 162
Cdd:COG0770 77 -LIVVDDTLKALQQLAAAHRARFNIPVIAITGSNGKTTTKEMLAAVLSTKGKVLATPGNFNNEIGVPLTLLRLPEDHEFA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 163 VLEMGMNHFGEIDYLTQIAPPDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGELSPQV 242
Cdd:COG0770 156 VLEMGMNHPGEIAYLARIARPDIAVITNIGPAHLEGFGSLEGIARAKGEIFEGLPPGGVAVLNADDPLLAALAERAKARV 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 243 VFCGADRPAPYAAKEIrQLGSKGLRCRVITPKNDFSVTVPALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFVPTKMR 322
Cdd:COG0770 236 LTFGLSEDADVRAEDI-ELDEDGTRFTLHTPGGELEVTLPLPGRHNVSNALAAAAVALALGLDLEEIAAGLAAFQPVKGR 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 323 MNVIH-QGDITILDDAYNANPQSMRAALEILSQTEGA-YRAAVLGDMFELGDLGPELHRSMGECAGALGnIDGLLAVGEL 400
Cdd:COG0770 315 LEVIEgAGGVTLIDDSYNANPDSMKAALDVLAQLPGGgRRIAVLGDMLELGEESEELHREVGELAAELG-IDRLFTVGEL 393
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 524045452 401 AWNIYDAAhqsGITQALYARDRTAAKELLPNLVRPGAVILVKASRGMAFEELTREIQRLAP 461
Cdd:COG0770 394 ARAIAEAA---GGERAEHFEDKEELLAALKALLRPGDVVLVKGSRGMGLERVVEALKEGAA 451
|
|
| murF |
TIGR01143 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the ... |
33-452 |
1.60e-147 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the strictly bacterial MurF gene of peptidoglycan biosynthesis. This enzyme is almost always UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase, but in a few species, MurE adds lysine rather than diaminopimelate. This enzyme acts on the product from MurE activity, and so is also subfamily rather than equivalog. Staphylococcus aureus is an example of species in this MurF protein would differ. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273468 [Multi-domain] Cd Length: 417 Bit Score: 427.07 E-value: 1.60e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 33 TDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTEEvPQVLLPGKFYIQVEDTMLAIGQVARAYREKFPIPVIGI 112
Cdd:TIGR01143 1 TDSRAIKPGDLFIALKGERFDGHDFVEQALAAGAVAVVVDR-EVGPDNGLPQILVDDTLEALQALARAKRAKFSGKVIGI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 113 TGSVGKTTTKDMVASVLGQKFRVLKTEGNFNNELGLPLTLFRLTAQHQICVLEMGMNHFGEIDYLTQIAPPDVAVITNIG 192
Cdd:TIGR01143 80 TGSSGKTTTKEMLAAILSHKYKVFATPGNFNNEIGLPLTLLRAPGDHDYAVLEMGASHPGEIAYLAEIAKPDIAVITNIG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 193 DAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGELSPQVVFCGADRPAPYAAKEIrQLGSKGL-RCRVI 271
Cdd:TIGR01143 160 PAHLEGFGSLEGIAEAKGEILQGLKENGIAVINADDPAFADLAKRLPNRNILSFGFEGGDFVAKDI-SYSALGStSFTLV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 272 TPKNDFSVTVPALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFVPTKMRMNVIHQGDITILDDAYNANPQSMRAALEI 351
Cdd:TIGR01143 239 APGGEFEVSLPLLGRHNVMNALAAAALALELGIPLEEIAEGLAELKLVKGRFEVQTKNGLTLIDDTYNANPDSMRAALDA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 352 LSQTEGaYRAAVLGDMFELGDLGPELHRSMGECAGALGnIDGLLAVGELAWNIYDAAHqsgiTQALYARDRTAAKELLPN 431
Cdd:TIGR01143 319 LARFPG-KKILVLGDMAELGEYSEELHAEVGRYANSLG-IDLVFLVGEEAAVIYDSFG----KQGKHFADKDELLAFLKT 392
|
410 420
....*....|....*....|.
gi 524045452 432 LVRPGAVILVKASRGMAFEEL 452
Cdd:TIGR01143 393 LVRKGDVVLVKGSRSVKLEKV 413
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
8-457 |
5.98e-122 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 378.28 E-value: 5.98e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 8 ELLTATGGRLLGEEAVAERTITGVETDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTE-EVPQVLLPGkfyIQ 86
Cdd:PRK11929 506 IKLRAAKGGSNSLQINSLPHAGAVSTDSRSVGRGELFVALRGENFDGHDYLPQAFAAGACAAVVErQVADVDLPQ---IV 582
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 87 VEDTMLAIGQVARAYREKFPIPVIGITGSVGKTTTKDMVASVLGQ---KFRVLKTEGNFNNELGLPLTLFRLTAQHQICV 163
Cdd:PRK11929 583 VDDTRAALGRLATAWRARFSLPVVAITGSNGKTTTKEMIAAILAAwqgEDRVLATEGNFNNEIGVPLTLLRLRAQHRAAV 662
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 164 LEMGMNHFGEIDYLTQIAPPDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLrPLEGELSPQVV 243
Cdd:PRK11929 663 FELGMNHPGEIAYLAAIAAPTVALVTNAQREHQEFMHSVEAVARAKGEIIAALPEDGVAVVNGDDPYT-AIWAKLAGARR 741
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 244 FC------GADRPAPYAAKEIRQLGSKGLRCRVITPKNDFSVTVPALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFV 317
Cdd:PRK11929 742 VLrfglqpGADVYAEKIAKDISVGEAGGTRCQVVTPAGSAEVYLPLIGEHNLRNALAAIACALAAGASLKQIRAGLERFQ 821
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 318 PTKMRMNVIH-QGDITILDDAYNANPQSMRAALEILSQTEGAYRAAVLGDMFELGDLGPELHRSMGECAGALGnIDGLLA 396
Cdd:PRK11929 822 PVAGRMQRRRlSCGTRIIDDTYNANPDSMRAAIDVLAELPNGPRALVLGDMLELGDNGPAMHREVGKYARQLG-IDALIT 900
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 524045452 397 VGELAWNIYDAAHQSGITQalyARDRTAAKELLPNLVRPGAVILVKASRGMAFEELTREIQ 457
Cdd:PRK11929 901 LGEAARDAAAAFGAGARGV---CASVDEIIAALRGALPEGDSVLIKGSRFMRLERVVDALS 958
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
112-299 |
5.01e-47 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 160.93 E-value: 5.01e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 112 ITGSVGKTTTKDMVASVLGQKFRVLKTEG--------NFNNELGLPLTLFRLTAQ-HQICVLEMGMNHFGEiDYLTQIAP 182
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILSLAGGVIGTIGtyigksgnTTNNAIGLPLTLAEMVEAgAEYAVLEVSSHGLGE-GRLSGLLK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 183 PDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGELSPQ---VVFCGADRPAPYAAKEIr 259
Cdd:pfam08245 80 PDIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINADDPYGAFLIAKLKKAgvrVITYGIEGEADLRAANI- 158
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 524045452 260 QLGSKGLRCRVITPKND-FSVTVPALGGHMIYPVLMACAIG 299
Cdd:pfam08245 159 ELSSDGTSFDLFTVPGGeLEIEIPLLGRHNVYNALAAIAAA 199
|
|
| F430_CfbE |
NF033197 |
coenzyme F430 synthase; Members of this family are coenzyme F430 synthase, involving in ... |
93-342 |
3.39e-10 |
|
coenzyme F430 synthase; Members of this family are coenzyme F430 synthase, involving in synthesizing coenzyme F430, which is used in methanogens by coenzyme M reductase. Members of this family are restricted to archaeal methanogens, and resemble (and may be misannotated as) MurD, an enzyme of bacterial cell wall biosynthesis.
Pssm-ID: 467992 [Multi-domain] Cd Length: 419 Bit Score: 61.57 E-value: 3.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 93 AIGQVARAYREKFPIPVIGITGSVGKTTTKDMVASVLGQKFRVLKT-EGNFNNELGLPLTLFRLTAQHQICVLEmGMNHF 171
Cdd:NF033197 78 AVGEILKKKYGRIPKKFIEITGVKGKTTTAELLAHILSDEYVLLHTsRGTERYPEGELSNKGSITPASILNALE-LAEEI 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 172 GEIDY----------LTQIAppDVAVITNIGdahiENLGSRAG---ILQAKKEIFHRMTPeGMAVLNGDDAMLRPLEGEL 238
Cdd:NF033197 157 GIDDYgflifevslgGTGAG--DVGIITNIL----EDYPIAGGkrsASAAKLQSLKNAKV-GSINVADLGIYINGKNKLV 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 239 SpqvvfcgadrpAPYAAKEIRQLGSKGLRCRVITPKNDFsvtvpALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFVP 318
Cdd:NF033197 230 I-----------TVAGVEILSKYPLRFKYGNTEFEFNPL-----LFGPHYRENSLFAIEAALNLGVDPEDIISALKGFKG 293
|
250 260
....*....|....*....|....
gi 524045452 319 TKMRMNVIHQGDITILDdayNANP 342
Cdd:NF033197 294 LPGRMAVKKEGGVVIVD---NINP 314
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MurF |
COG0770 |
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
3-461 |
0e+00 |
|
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl pentapeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440533 [Multi-domain] Cd Length: 451 Bit Score: 578.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 3 PMTVRELLTATGGRLLGEEAVaerTITGVETDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTEEVPQVLLPgk 82
Cdd:COG0770 2 LLTLAEIAEATGGRLIGDPDL---VVTGVSTDSRKIKPGDLFVALKGERFDGHDFVAQALAKGAAAALVSRPLPADLP-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 83 fYIQVEDTMLAIGQVARAYREKFPIPVIGITGSVGKTTTKDMVASVLGQKFRVLKTEGNFNNELGLPLTLFRLTAQHQIC 162
Cdd:COG0770 77 -LIVVDDTLKALQQLAAAHRARFNIPVIAITGSNGKTTTKEMLAAVLSTKGKVLATPGNFNNEIGVPLTLLRLPEDHEFA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 163 VLEMGMNHFGEIDYLTQIAPPDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGELSPQV 242
Cdd:COG0770 156 VLEMGMNHPGEIAYLARIARPDIAVITNIGPAHLEGFGSLEGIARAKGEIFEGLPPGGVAVLNADDPLLAALAERAKARV 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 243 VFCGADRPAPYAAKEIrQLGSKGLRCRVITPKNDFSVTVPALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFVPTKMR 322
Cdd:COG0770 236 LTFGLSEDADVRAEDI-ELDEDGTRFTLHTPGGELEVTLPLPGRHNVSNALAAAAVALALGLDLEEIAAGLAAFQPVKGR 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 323 MNVIH-QGDITILDDAYNANPQSMRAALEILSQTEGA-YRAAVLGDMFELGDLGPELHRSMGECAGALGnIDGLLAVGEL 400
Cdd:COG0770 315 LEVIEgAGGVTLIDDSYNANPDSMKAALDVLAQLPGGgRRIAVLGDMLELGEESEELHREVGELAAELG-IDRLFTVGEL 393
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 524045452 401 AWNIYDAAhqsGITQALYARDRTAAKELLPNLVRPGAVILVKASRGMAFEELTREIQRLAP 461
Cdd:COG0770 394 ARAIAEAA---GGERAEHFEDKEELLAALKALLRPGDVVLVKGSRGMGLERVVEALKEGAA 451
|
|
| murF |
TIGR01143 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the ... |
33-452 |
1.60e-147 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the strictly bacterial MurF gene of peptidoglycan biosynthesis. This enzyme is almost always UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase, but in a few species, MurE adds lysine rather than diaminopimelate. This enzyme acts on the product from MurE activity, and so is also subfamily rather than equivalog. Staphylococcus aureus is an example of species in this MurF protein would differ. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273468 [Multi-domain] Cd Length: 417 Bit Score: 427.07 E-value: 1.60e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 33 TDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTEEvPQVLLPGKFYIQVEDTMLAIGQVARAYREKFPIPVIGI 112
Cdd:TIGR01143 1 TDSRAIKPGDLFIALKGERFDGHDFVEQALAAGAVAVVVDR-EVGPDNGLPQILVDDTLEALQALARAKRAKFSGKVIGI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 113 TGSVGKTTTKDMVASVLGQKFRVLKTEGNFNNELGLPLTLFRLTAQHQICVLEMGMNHFGEIDYLTQIAPPDVAVITNIG 192
Cdd:TIGR01143 80 TGSSGKTTTKEMLAAILSHKYKVFATPGNFNNEIGLPLTLLRAPGDHDYAVLEMGASHPGEIAYLAEIAKPDIAVITNIG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 193 DAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGELSPQVVFCGADRPAPYAAKEIrQLGSKGL-RCRVI 271
Cdd:TIGR01143 160 PAHLEGFGSLEGIAEAKGEILQGLKENGIAVINADDPAFADLAKRLPNRNILSFGFEGGDFVAKDI-SYSALGStSFTLV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 272 TPKNDFSVTVPALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFVPTKMRMNVIHQGDITILDDAYNANPQSMRAALEI 351
Cdd:TIGR01143 239 APGGEFEVSLPLLGRHNVMNALAAAALALELGIPLEEIAEGLAELKLVKGRFEVQTKNGLTLIDDTYNANPDSMRAALDA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 352 LSQTEGaYRAAVLGDMFELGDLGPELHRSMGECAGALGnIDGLLAVGELAWNIYDAAHqsgiTQALYARDRTAAKELLPN 431
Cdd:TIGR01143 319 LARFPG-KKILVLGDMAELGEYSEELHAEVGRYANSLG-IDLVFLVGEEAAVIYDSFG----KQGKHFADKDELLAFLKT 392
|
410 420
....*....|....*....|.
gi 524045452 432 LVRPGAVILVKASRGMAFEEL 452
Cdd:TIGR01143 393 LVRKGDVVLVKGSRSVKLEKV 413
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
8-457 |
5.98e-122 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 378.28 E-value: 5.98e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 8 ELLTATGGRLLGEEAVAERTITGVETDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTE-EVPQVLLPGkfyIQ 86
Cdd:PRK11929 506 IKLRAAKGGSNSLQINSLPHAGAVSTDSRSVGRGELFVALRGENFDGHDYLPQAFAAGACAAVVErQVADVDLPQ---IV 582
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 87 VEDTMLAIGQVARAYREKFPIPVIGITGSVGKTTTKDMVASVLGQ---KFRVLKTEGNFNNELGLPLTLFRLTAQHQICV 163
Cdd:PRK11929 583 VDDTRAALGRLATAWRARFSLPVVAITGSNGKTTTKEMIAAILAAwqgEDRVLATEGNFNNEIGVPLTLLRLRAQHRAAV 662
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 164 LEMGMNHFGEIDYLTQIAPPDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLrPLEGELSPQVV 243
Cdd:PRK11929 663 FELGMNHPGEIAYLAAIAAPTVALVTNAQREHQEFMHSVEAVARAKGEIIAALPEDGVAVVNGDDPYT-AIWAKLAGARR 741
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 244 FC------GADRPAPYAAKEIRQLGSKGLRCRVITPKNDFSVTVPALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFV 317
Cdd:PRK11929 742 VLrfglqpGADVYAEKIAKDISVGEAGGTRCQVVTPAGSAEVYLPLIGEHNLRNALAAIACALAAGASLKQIRAGLERFQ 821
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 318 PTKMRMNVIH-QGDITILDDAYNANPQSMRAALEILSQTEGAYRAAVLGDMFELGDLGPELHRSMGECAGALGnIDGLLA 396
Cdd:PRK11929 822 PVAGRMQRRRlSCGTRIIDDTYNANPDSMRAAIDVLAELPNGPRALVLGDMLELGDNGPAMHREVGKYARQLG-IDALIT 900
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 524045452 397 VGELAWNIYDAAHQSGITQalyARDRTAAKELLPNLVRPGAVILVKASRGMAFEELTREIQ 457
Cdd:PRK11929 901 LGEAARDAAAAFGAGARGV---CASVDEIIAALRGALPEGDSVLIKGSRFMRLERVVDALS 958
|
|
| murF |
PRK10773 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed |
1-457 |
1.74e-103 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed
Pssm-ID: 182718 [Multi-domain] Cd Length: 453 Bit Score: 315.82 E-value: 1.74e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 1 MEPMTVRELLTATGGRLLGeeavAERTITGVETDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTE-----EVP 75
Cdd:PRK10773 1 MISVTLSQLADILNGELQG----ADITIDAVTTDTRKVTPGCLFVALKGERFDAHDFADDAKAAGAGALLVSrpldiDLP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 76 QVLlpgkfyiqVEDTMLAIGQVARAYREKFPIPVIGITGSVGKTTTKDMVASVLGQKFRVLKTEGNFNNELGLPLTLFRL 155
Cdd:PRK10773 77 QLV--------VKDTRLAFGQLAAWVRQQVPARVVALTGSSGKTSVKEMTAAILRQCGNTLYTAGNLNNDIGVPLTLLRL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 156 TAQHQICVLEMGMNHFGEIDYLTQIAPPDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLE 235
Cdd:PRK10773 149 TPEHDYAVIELGANHQGEIAYTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADSNDWLNWQ 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 236 GELSPQVVFcgadRPAPYAAKEIR------QLGSKGLRCRVITPKNDFSVTVPALGGHMIYPVLMACAIGERFGMTGEEM 309
Cdd:PRK10773 229 SVIGSKTVW----RFSPNAANSVDftatniHVTSHGTEFTLHTPTGSVDVLLPLPGRHNIANALAAAALAMSVGATLDAV 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 310 KAGIEAFVPTKMRMNVIHQG-DITILDDAYNANPQSMRAALEILSQTEGaYRAAVLGDMFELGDLGPELHRSMGEcAGAL 388
Cdd:PRK10773 305 KAGLANLKAVPGRLFPIQLAeGQLLLDDSYNANVGSMTAAAQVLAEMPG-YRVMVVGDMAELGAESEACHRQVGE-AAKA 382
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 524045452 389 GNIDGLLAVGELAWNIYDAahqSGITQalYARDRTAAKELLPNLVRPGAVI--LVKASRGMAFEELTREIQ 457
Cdd:PRK10773 383 AGIDKVLSVGKLSHAISEA---SGVGE--HFADKTALIARLKALLAEHQVItiLVKGSRSAAMEEVVRALQ 448
|
|
| PRK14093 |
PRK14093 |
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; ... |
5-446 |
1.32e-69 |
|
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase; Provisional
Pssm-ID: 184501 [Multi-domain] Cd Length: 479 Bit Score: 228.89 E-value: 1.32e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 5 TVRELLTATGGRLLGEEAvaeRTITGVETDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTE-EVPQVLLPGKF 83
Cdd:PRK14093 8 TSDAMAEAMGATRSGALP---RDVTGISIDSRTLAPGDAYFAIKGDVHDGHAFVAAALKAGAALAVVErAQRDKFAADAP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 84 YIQVEDTMLAIGQVARAYREKFPIPVIGITGSVGKTTTKDMVASVLGQKFRVLKTEGNFNNELGLPLTLFRLTAQHQICV 163
Cdd:PRK14093 85 LLVVDDVLAALRDLGRAARARLEAKVIAVTGSVGKTSTKEALRGVLGAQGETHASVASFNNHWGVPLSLARCPADARFAV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 164 LEMGMNHFGEIDYLTQIAPPDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGELSP--- 240
Cdd:PRK14093 165 FEIGMNHAGEIEPLVKMVRPHVAIITTVEPVHLEFFSGIEAIADAKAEIFTGLEPGGAAVLNRDNPQFDRLAASARAagi 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 241 -QVVFCGADRPAPYAAKEIR-QLGSKGLRCRVITPKNDFSVTVPalGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFVP 318
Cdd:PRK14093 245 aRIVSFGADEKADARLLDVAlHADCSAVHADILGHDVTYKLGMP--GRHIAMNSLAVLAAAELAGADLALAALALSQVQP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 319 TKMRmNVIH-----QGDITILDDAYNANPQSMRAALEILSQTE---GAYRAAVLGDMFELGDLGPELHRSMGECAGAlGN 390
Cdd:PRK14093 323 AAGR-GVRHtlevgGGEATLIDESYNANPASMAAALGVLGRAPvgpQGRRIAVLGDMLELGPRGPELHRGLAEAIRA-NA 400
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 524045452 391 IDGLLAVGELAWNIYDAAhqSGITQALYARDRTAAKELLPNLVRPGAVILVKASRG 446
Cdd:PRK14093 401 IDLVFCCGPLMRNLWDAL--SSGKRGGYAEDAAALESQVVAAIRAGDVIMVKGSLG 454
|
|
| PRK11930 |
PRK11930 |
putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine ... |
5-458 |
3.66e-63 |
|
putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Provisional
Pssm-ID: 237026 [Multi-domain] Cd Length: 822 Bit Score: 219.06 E-value: 3.66e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 5 TVRELLTATGGRLLGEEAVaerTITGVETDSRAVH--EGDLFVALRGERTDGHRYIASALETGAAGCL--TEEVPQVLLP 80
Cdd:PRK11930 4 TLESISGILGAEGLGDKDA---IIDQILTDSRSLSfpENTLFFALKGERNDGHRYIQELYEKGVRNFVvsEEKHPEESYP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 81 GKFYIQVEDTMLAIGQVARAYREKFPIPVIGITGSVGKTTTKDMVASVLGQKFRVLKTEGNFNNELGLPLTLFRLTAQHQ 160
Cdd:PRK11930 81 DANFLKVKDPLKALQELAAYHRSQFDIPVIGITGSNGKTIVKEWLYQLLSPDYNIVRSPRSYNSQIGVPLSVWQLNEEHE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 161 ICVLEMGMNHFGEIDYLTQIAPPDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMtpeGMAVLNGDDAmlrplegELSP 240
Cdd:PRK11930 161 LGIFEAGISQPGEMEALQKIIKPTIGILTNIGGAHQENFRSIKQKIMEKLKLFKDC---DVIIYNGDNE-------LISS 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 241 QVVFCGA-------DRPAPYAAKEIRQLGSKGLRC--RVITPKNDFSVTVPALGGHMIYPVLMACAIGERFGMTGEEMKA 311
Cdd:PRK11930 231 CITKSNLtlkliswSRKDPEAPLYIPFVEKKEDHTviSYTYKGEDFHFEIPFIDDASIENLIHCIAVLLYLGYSADQIQE 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 312 GIEAFVPTKMRMNViHQGDI--TILDDAYNANPQSMRAALEIL-SQTEGAYRAAVLGDMFELGDLGPELHRSMGECAGAL 388
Cdd:PRK11930 311 RMARLEPVAMRLEV-KEGINncTLINDSYNSDLQSLDIALDFLnRRSQSKKKTLILSDILQSGQSPEELYRKVAQLISKR 389
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 389 GnIDGLLAVGElawNIYDAAHQSGITQALYARDRTAAKELLPNLVRPGAVILVKASRGMAFEELTREIQR 458
Cdd:PRK11930 390 G-IDRLIGIGE---EISSEASKFEGTEKEFFKTTEAFLKSFAFLKFRNELILVKGARKFEFEQITELLEQ 455
|
|
| MurE |
COG0769 |
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
30-350 |
2.14e-48 |
|
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl tripeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440532 [Multi-domain] Cd Length: 459 Bit Score: 172.19 E-value: 2.14e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 30 GVETDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTEEVPQVLLPGKFYIQVEDTMLAIGQVARAY--REKFPI 107
Cdd:COG0769 1 GITYDSRKVKPGDLFVALPGARVDGHDFIAQAIARGAVAVVTEAPGALLAAGVPVIVVPDPRAALALLAAAFygHPSQKL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 108 PVIGITGSVGKTTTKDMVASVL---GQKFRVLKTEGN-FNNEL---GL----PLTLFRLTAQhqicVLEMGMNHF----- 171
Cdd:COG0769 81 KLIGVTGTNGKTTTTYLLAQILralGKKTGLIGTVGNgIGGELipsSLttpeALDLQRLLAE----MVDAGVTHVvmevs 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 172 ------GEIDYLtqiaPPDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGELSPQVVFC 245
Cdd:COG0769 157 shaldqGRVDGV----RFDVAVFTNLTRDHLDYHGTMEAYFAAKARLFDQLGPGGAAVINADDPYGRRLAAAAPARVITY 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 246 GADRPAPYAAKEIRqLGSKGLRCRVITPKNDFSVTVPALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFVPTKMRMNV 325
Cdd:COG0769 233 GLKADADLRATDIE-LSADGTRFTLVTPGGEVEVRLPLIGRFNVYNALAAIAAALALGIDLEEILAALEKLKGVPGRMER 311
|
330 340
....*....|....*....|....*.
gi 524045452 326 IHQG-DITILDDaYNANPQSMRAALE 350
Cdd:COG0769 312 VDGGqGPTVIVD-YAHTPDALENVLE 336
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
112-299 |
5.01e-47 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 160.93 E-value: 5.01e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 112 ITGSVGKTTTKDMVASVLGQKFRVLKTEG--------NFNNELGLPLTLFRLTAQ-HQICVLEMGMNHFGEiDYLTQIAP 182
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILSLAGGVIGTIGtyigksgnTTNNAIGLPLTLAEMVEAgAEYAVLEVSSHGLGE-GRLSGLLK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 183 PDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGELSPQ---VVFCGADRPAPYAAKEIr 259
Cdd:pfam08245 80 PDIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINADDPYGAFLIAKLKKAgvrVITYGIEGEADLRAANI- 158
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 524045452 260 QLGSKGLRCRVITPKND-FSVTVPALGGHMIYPVLMACAIG 299
Cdd:pfam08245 159 ELSSDGTSFDLFTVPGGeLEIEIPLLGRHNVYNALAAIAAA 199
|
|
| murE |
TIGR01085 |
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, ... |
26-352 |
6.76e-37 |
|
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase. An exception is Staphylococcus aureus, in which diaminopimelate is replaced by lysine in the peptidoglycan and MurE is EC 6.3.2.7. The Mycobacteria, part of the closest neighboring branch outside of the low-GC Gram-positive bacteria, use diaminopimelate. A close homolog, scoring just below the trusted cutoff, is found (with introns) in Arabidopsis thaliana. Its role is unknown. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273435 [Multi-domain] Cd Length: 464 Bit Score: 140.91 E-value: 6.76e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 26 RTITGVETDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTEEVPQVLLPGKFYIQVEDTMLAIGQVARAYREkF 105
Cdd:TIGR01085 2 LEVTGLTLDSREVKPGDLFVAIKGTHVDGHDFIHDAIANGAVAVVVERDVDFYVAPVPVIIVPDLRHALSSLAAAFYG-H 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 106 P---IPVIGITGSVGKTTTKDMVASVL---GQKFRVLKTEGNF---NNELGLPL------------TLFRLTAQH-QICV 163
Cdd:TIGR01085 81 PskkLKVIGVTGTNGKTTTTSLIAQLLrllGKKTGLIGTIGYRlggNDLIKNPAalttpealtlqsTLAEMVEAGaQYAV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 164 LE-----MGMNHFGEIDYltqiappDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGEL 238
Cdd:TIGR01085 161 MEvsshaLAQGRVRGVRF-------DAAVFTNLSRDHLDFHGTMENYFAAKASLFTELGLKRFAVINLDDEYGAQFVKRL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 239 SPQVVFCGADRPAPYAAKEIRQ----LGSKGLRCRVITPKNDFSVTVPALGGHMIYPVLMACAIGERFGMTG-EEMKAGI 313
Cdd:TIGR01085 234 PKDITVSAITQPADGRAQDIKItdsgYSFEGQQFTFETPAGEGHLHTPLIGRFNVYNLLAALATLLHLGGIDlEDIVAAL 313
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 524045452 314 EAFVPTKMRMNVIHQG-DITILDDaYNANPQSMRAALEIL 352
Cdd:TIGR01085 314 EKFRGVPGRMELVDGGqKFLVIVD-YAHTPDALEKALRTL 352
|
|
| murE |
PRK00139 |
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional |
21-352 |
6.19e-34 |
|
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional
Pssm-ID: 234660 [Multi-domain] Cd Length: 460 Bit Score: 132.56 E-value: 6.19e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 21 EAVAERTITGVETDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTEEVPqVLLPGKFYIQVEDTMLAIGQVARA 100
Cdd:PRK00139 8 DLLAPVEITGLTYDSRKVKPGDLFVALPGHKVDGRDFIAQAIANGAAAVVAEADG-EAGTGVPVIIVPDLRKALALLAAA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 101 Y--REKFPIPVIGITGSVGKTTTKDMVASVL---GQKFRVLKTEGNF----NNELGL----PLTLFRLTAQhqicVLEMG 167
Cdd:PRK00139 87 FygHPSDKLKLIGVTGTNGKTTTAYLLAQILrllGEKTALIGTLGNGiggeLIPSGLttpdALDLQRLLAE----LVDAG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 168 MNHF-----------GEIDYLTQiappDVAVITNIGDAHIENLGSRAGILQAKKEIFHRmtPEGMAVLNGDDAMLRPLeg 236
Cdd:PRK00139 163 VTYAamevsshaldqGRVDGLKF----DVAVFTNLSRDHLDYHGTMEDYLAAKARLFSE--LGLAAVINADDEVGRRL-- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 237 eLSPQVVFCGADRPAPYAAKEIRqLGSKGLRCRVITPkndfsVTVPALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAF 316
Cdd:PRK00139 235 -LALPDAYAVSMAGADLRATDVE-YTDSGQTFTLVTE-----VESPLIGRFNVSNLLAALAALLALGVPLEDALAALAKL 307
|
330 340 350
....*....|....*....|....*....|....*..
gi 524045452 317 VPTKMRMNVIHQGD-ITILDDaYNANPQSMRAALEIL 352
Cdd:PRK00139 308 QGVPGRMERVDAGQgPLVIVD-YAHTPDALEKVLEAL 343
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
26-352 |
5.88e-30 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 123.66 E-value: 5.88e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 26 RTITGVETDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTEE--VPQVLLPGKFYIQVEDTMLAIGQVARAYRE 103
Cdd:PRK11929 27 AATADLRLDSREVQPGDLFVACRGAASDGRAFIDQALARGAAAVLVEAegEDQVAAADALVLPVADLRKALGELAARWYG 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 104 KFPIP--VIGITGSVGKTTTKDMVASVL---GQKFRVLKTEGNF--NNELGLPLT------LFRLTAQH-----QICVLE 165
Cdd:PRK11929 107 RPSEQlsLVAVTGTNGKTSCAQLLAQLLtrlGKPCGSIGTLGARldGRLIPGSLTtpdaiiLHRILARMraagaDAVAME 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 166 -----MGMNHFGEIDYltqiappDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDA----MLRPLEG 236
Cdd:PRK11929 187 asshgLEQGRLDGLRI-------AVAGFTNLTRDHLDYHGTMQDYEEAKAALFSKLPGLGAAVINADDPaaarLLAALPR 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 237 ELspQVVFCGADRPAPYAAKEIRQlGSKGLRCRVITPKNDFSVTVPALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAF 316
Cdd:PRK11929 260 GL--KVGYSPQNAGADVQARDLRA-TAHGQVFTLATPDGSYQLVTRLLGRFNVSNLLLVAAALKKLGLPLAQIARALAAV 336
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 524045452 317 VPTKMRMNVIH-----QGDITILDdaYNANPQSMRAALEIL 352
Cdd:PRK11929 337 SPVPGRMERVGptagaQGPLVVVD--YAHTPDALAKALTAL 375
|
|
| MurD |
COG0771 |
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ... |
94-350 |
1.02e-23 |
|
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440534 [Multi-domain] Cd Length: 445 Bit Score: 103.24 E-value: 1.02e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 94 IGQVARAYREkFPIPVIGITGSVGKTTTKDMVASVL---GQKFRVLkteGNfnneLGLP-LTLFRLTAQHQICVLE---- 165
Cdd:COG0771 93 IGEIELAYRL-SPAPIIAITGTNGKTTTTTLIGHILkaaGLRVAVG---GN----IGTPlLDLLLEPEPPDVYVLElssf 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 166 --MGMNHFGeidyltqiapPDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGELSPQVV 243
Cdd:COG0771 165 qlETTPSLR----------PDVAVILNITPDHLDRHGSMEAYAAAKARIFANQTPDDYAVLNADDPLTRALAEEAKARVV 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 244 FCGADRPAPYAAkeirqlgskGLRCR--VITPKNDFSVTVPAL---GGHMIYPVLMACAIGERFGMTGEEMKAGIEAFVP 318
Cdd:COG0771 235 PFSLKEPLEGGA---------GLEDGklVDRASGEELLPVDDLrlpGRHNLENALAALAAARALGVPPEAIREALRSFKG 305
|
250 260 270
....*....|....*....|....*....|...
gi 524045452 319 TKMRMNVIHQ-GDITILDDAYNANPQSMRAALE 350
Cdd:COG0771 306 LPHRLEFVAEiNGVRFINDSKATNPDATLAALE 338
|
|
| murD |
TIGR01087 |
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation ... |
94-454 |
8.50e-22 |
|
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273436 [Multi-domain] Cd Length: 433 Bit Score: 97.41 E-value: 8.50e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 94 IGQVARAYReKFPIPVIGITGSVGKTTTKDMVASVLGQKFRVLKTEGNFnnelGLPLTLFRLTAQHQICVLEMgmNHFgE 173
Cdd:TIGR01087 90 VGDIELFLR-LVPLPVVAITGTNGKTTTTSLLYHLLKAAGLKAFLGGNI----GTPALEVLDQEGAELYVLEL--SSF-Q 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 174 IDYLTQIAPPdVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGELSPQVVFCGADRpapY 253
Cdd:TIGR01087 162 LETTESLRPE-IALILNISEDHLDWHGSFEDYVAAKLKIFARQTEGDVAVLNADDPRFARLAQKSKAQVIWFSVEK---D 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 254 AAKEIRQLGSKglrcRVItpkNDFSVTVPALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFVPTKMRMNVIHQGD-IT 332
Cdd:TIGR01087 238 AERGLCIRDGG----LYL---KPNDLEGSLLGLHNAENILAAIALAKSLGLNLEAILEALRSFKGLPHRLEYVGQKNgVH 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 333 ILDDAYNANPQSMRAALeilsqtEGAYRAAVL--GDMFELGDLGPELHRsmgecagALGNIDGLLAVGELAWNIYDAAHQ 410
Cdd:TIGR01087 311 FYNDSKATNVHATLAAL------SAFDNPVILivGGDDKGADFSPLAPA-------AAGKVKAVLAIGEDAAKIAPLLKE 377
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 524045452 411 SGITQALYARDRTAAKELLPNLVRPGAVILVKAS-----------RGMAFEELTR 454
Cdd:TIGR01087 378 AGLSVYLVESLEEAVQAAREVASPGDVVLLSPACasfdqfksyeeRGEKFKELVR 432
|
|
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
109-441 |
1.96e-21 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 96.29 E-value: 1.96e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 109 VIGITGSVGKTTTKDMVASVLgqkfrvlktegnfnNELGLPLTLF---RLTAQHqicvlemGMNHFGEIDYLtqIA---- 181
Cdd:COG0773 106 SIAVAGTHGKTTTTSMLAHIL--------------EEAGLDPTFLiggILNNFG-------TNARLGDGDYF--VAeade 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 182 --------PPDVAVITNIgDA-HIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGELSPQVVFCGADRPAP 252
Cdd:COG0773 163 sdgsflhySPDIAVVTNI-EAdHLDIYGDLEAIKEAFHEFARNVPFYGLLVLCADDPGLRELLPRCGRPVITYGFSEDAD 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 253 YAAKEIRQLGSkGLRCRVITPKNDF-SVTVPALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFVPTKMRMNVIHQ-GD 330
Cdd:COG0773 242 YRAENIRIDGG-GSTFDVLRRGEELgEVELNLPGRHNVLNALAAIAVALELGVDPEAIAEALASFKGVKRRFELKGEvGG 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 331 ITILDDaYNANPQSMRAALEILSQTEGAYR-AAVLgdmfelgdlgpELHR--SMGEC----AGALGNIDGLL-----AVG 398
Cdd:COG0773 321 VTVIDD-YAHHPTEIAATLAAAREKYPDRRlVAVF-----------QPHRysRTRDFldefAEALSLADEVIlldiyAAR 388
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 524045452 399 EL---AWN---IYDAAHQSGiTQALYARDRTAAKELLPNLVRPGAVILV 441
Cdd:COG0773 389 EKpipGVSsedLAEAIRKRG-KDVVYVPDLDELVEALAEIARPGDVVLT 436
|
|
| murD |
PRK14106 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional |
94-455 |
6.50e-15 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional
Pssm-ID: 184511 [Multi-domain] Cd Length: 450 Bit Score: 76.55 E-value: 6.50e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 94 IGQVARAYREKfPIPVIGITGSVGKTTTKDMVASVLGQKFRVLKTEGNfnneLGLPLTLFRLTAQHQ-ICVLEMGMNHFG 172
Cdd:PRK14106 96 IGEVELAYRFS-KAPIVAITGTNGKTTTTTLLGEIFKNAGRKTLVAGN----IGYPLIDAVEEYGEDdIIVAEVSSFQLE 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 173 EIDYLTqiapPDVAVITNIGDAHIENLGSRAGILQAKKEIFHRMTPEGMAVLNGDDAMLRPLEGELSPQVVFcgadrpap 252
Cdd:PRK14106 171 TIKEFK----PKVGCILNITPDHLDRHKTMENYIKAKARIFENQRPSDYTVLNYDDPRTRSLAKKAKARVIF-------- 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 253 YAAKEIRQLG-----------SKGLRCRVItPKNDfsvtVPALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFVPTKM 321
Cdd:PRK14106 239 FSRKSLLEEGvfvkngkivisLGGKEEEVI-DIDE----IFIPGEHNLENALAATAAAYLLGISPDVIANTLKTFKGVEH 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 322 RMNVIHQ-GDITILDDAYNANPQSMRAALEILSQ----TEGAYraavlgdmfelgDLGPELHRSMGECAgalGNIDGLLA 396
Cdd:PRK14106 314 RIEFVAEiNGVKFINDSKGTNPDAAIKALEAYETpivlIAGGY------------DKGSDFDEFAKAFK---EKVKKLIL 378
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 524045452 397 VGELAWNIYDAAHQSGITQALYARDRTAAKELLPNLVRPGAVILVK---AS---------RGMAFEELTRE 455
Cdd:PRK14106 379 LGETAQEIAEAARKYGFDNILFAETLEEAVKKAYEIAKPGDVVLLSpacASwdmfknfeeRGRLFKELVLE 449
|
|
| Mur_ligase |
pfam01225 |
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes ... |
27-102 |
8.35e-12 |
|
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460121 [Multi-domain] Cd Length: 84 Bit Score: 60.71 E-value: 8.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 27 TITGVETDSRAVHEGDLFVALRGERTDGHRYIASALETGAAGCLTE-----------EVPQVLLPGkfyIQVEDTMLAIG 95
Cdd:pfam01225 1 EIHFVGIDGRGMSPGALFLALKGYRVDGSDFIESLIALGAAAVVGHdaannispdnpELEAAKVPG---IPVIDRREALA 77
|
....*..
gi 524045452 96 QVARAYR 102
Cdd:pfam01225 78 ELAAAFY 84
|
|
| PRK14016 |
PRK14016 |
cyanophycin synthetase; Provisional |
89-325 |
6.50e-11 |
|
cyanophycin synthetase; Provisional
Pssm-ID: 237586 [Multi-domain] Cd Length: 727 Bit Score: 64.41 E-value: 6.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 89 DTMLAIGQVARayrekfpIPVIGITGSVGKTTTKDMVASVL---GQKFRVLKTEGNF-NNEL-------GlPLTLfRLTA 157
Cdd:PRK14016 469 DMLFPEGDDGR-------IPIVAVTGTNGKTTTTRLIAHILklsGKRVGMTTTDGVYiDGRLidkgdctG-PKSA-RRVL 539
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 158 QH---QICVLEmgmNHFGEI-------DYLtqiappDVAVITNIGDAH--------IENLGS-RAGILQAKKeifhrmtP 218
Cdd:PRK14016 540 MNpdvEAAVLE---TARGGIlreglayDRC------DVGVVTNIGEDHlglggintLEDLAKvKRVVVEAVK-------P 603
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 219 EGMAVLNGDDAMLRPLEGELSPQVVFCGADRPAPYAAKEIRQLG------------SKGLRCRVITPKNDFSVTVPALGG 286
Cdd:PRK14016 604 DGYAVLNADDPMVAAMAERCKGKVIFFSMDPDNPVIAEHRAQGGravyvegdyivlAEGGWEIRIISLADIPLTLGGKAG 683
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 524045452 287 HMIYPVLMACAIGERFGMTGEEMKAGIEAFVP----TKMRMNV 325
Cdd:PRK14016 684 FNIENALAAIAAAWALGIDIELIRAGLRTFVSdaaqAPGRFNL 726
|
|
| F430_CfbE |
NF033197 |
coenzyme F430 synthase; Members of this family are coenzyme F430 synthase, involving in ... |
93-342 |
3.39e-10 |
|
coenzyme F430 synthase; Members of this family are coenzyme F430 synthase, involving in synthesizing coenzyme F430, which is used in methanogens by coenzyme M reductase. Members of this family are restricted to archaeal methanogens, and resemble (and may be misannotated as) MurD, an enzyme of bacterial cell wall biosynthesis.
Pssm-ID: 467992 [Multi-domain] Cd Length: 419 Bit Score: 61.57 E-value: 3.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 93 AIGQVARAYREKFPIPVIGITGSVGKTTTKDMVASVLGQKFRVLKT-EGNFNNELGLPLTLFRLTAQHQICVLEmGMNHF 171
Cdd:NF033197 78 AVGEILKKKYGRIPKKFIEITGVKGKTTTAELLAHILSDEYVLLHTsRGTERYPEGELSNKGSITPASILNALE-LAEEI 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 172 GEIDY----------LTQIAppDVAVITNIGdahiENLGSRAG---ILQAKKEIFHRMTPeGMAVLNGDDAMLRPLEGEL 238
Cdd:NF033197 157 GIDDYgflifevslgGTGAG--DVGIITNIL----EDYPIAGGkrsASAAKLQSLKNAKV-GSINVADLGIYINGKNKLV 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 239 SpqvvfcgadrpAPYAAKEIRQLGSKGLRCRVITPKNDFsvtvpALGGHMIYPVLMACAIGERFGMTGEEMKAGIEAFVP 318
Cdd:NF033197 230 I-----------TVAGVEILSKYPLRFKYGNTEFEFNPL-----LFGPHYRENSLFAIEAALNLGVDPEDIISALKGFKG 293
|
250 260
....*....|....*....|....
gi 524045452 319 TKMRMNVIHQGDITILDdayNANP 342
Cdd:NF033197 294 LPGRMAVKKEGGVVIVD---NINP 314
|
|
| Mur_ligase_C |
pfam02875 |
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase ... |
319-389 |
3.84e-09 |
|
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460731 [Multi-domain] Cd Length: 87 Bit Score: 53.50 E-value: 3.84e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 524045452 319 TKMRMNVIHQ-GDITILDDaYNANPQSMRAALEILSQTEGAYRAAVLGDMfelGDLGPELHRSMGECAGALG 389
Cdd:pfam02875 1 VPGRLEVVGEnNGVLVIDD-YAHNPDAMEAALRALRNLFPGRLILVFGGM---GDRDAEFHALLGRLAAALA 68
|
|
| PRK14022 |
PRK14022 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase; |
25-340 |
9.55e-09 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase;
Pssm-ID: 237588 [Multi-domain] Cd Length: 481 Bit Score: 57.35 E-value: 9.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 25 ERTITGVETDSRAVHEGDLFVALRGerTDGHRYIASALETGAAGCLTE-----EVPQVLlpgkfyiqVEDTMLAIGQVAR 99
Cdd:PRK14022 31 GVQFDDISYDSRTADEGTLFFAKGA--YFKHKFLQNAITQGLKLYVSEkdyevGIPQVI--------VPDIKKAMSLIAM 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 100 AYREkFP---IPVIGITGSVGKTTTKDMVASVLGQKFR---------VLKTEGNFNNELGLP--LTLFRLTAQhqiCVlE 165
Cdd:PRK14022 101 EFYD-NPqhkLKLLAFTGTKGKTTAAYFAYHILKQLHKpamlstmntTLDGETFFKSALTTPesLDLFKMMAE---AV-D 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 166 MGMNHF-----------GEIDYLTQiappDVAVITNIGDAHIENL--GSRAGILQAKKEIfhrMTPEGMAVLNGDDAMLR 232
Cdd:PRK14022 176 NGMTHLimevssqaylvGRVYGLTF----DVGVFLNITPDHIGPIehPTFEDYFYHKRLL---MENSKAVVVNSDMDHFS 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 233 PLEGELSPQ-VVFCGADRPAPYAAKEIRQLGSKGlrcrviTPKNDFSVTvpaLGGHMIYPVLMACAIG-ERFGMTGEEMK 310
Cdd:PRK14022 249 ELLEQVTPQeHDFYGIDSENQIMASNAFSFEATG------KLAGTYDIQ---LIGKFNQENAMAAGLAcLRLGASLEDIQ 319
|
330 340 350
....*....|....*....|....*....|..
gi 524045452 311 AGIEAfVPTKMRMNVIHQ--GDITILDDAYNA 340
Cdd:PRK14022 320 KGIAQ-TPVPGRMEVLTQsnGAKVFIDYAHNG 350
|
|
| LpxD |
COG1044 |
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [Cell wall/membrane/envelope ... |
3-112 |
2.32e-04 |
|
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [Cell wall/membrane/envelope biogenesis]; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase is part of the Pathway/BioSystem: Lipid A biosynthesis
Pssm-ID: 440666 [Multi-domain] Cd Length: 335 Bit Score: 43.08 E-value: 2.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 3 PMTVRELLTATGGRLLGEeavAERTITGVETDSRAVhEGDL-FVAlrgertdGHRYIASALETGAAGCLTEEVPQVLLPG 81
Cdd:COG1044 1 SFTLAELAELLGGELVGD---GDLEITGVAPLEEAG-PGDLsFLA-------NPKYAKQLATTKASAVIVPPDFAAALPG 69
|
90 100 110
....*....|....*....|....*....|.
gi 524045452 82 KFYIQVEDTMLAIGQVARAYREKFPIPViGI 112
Cdd:COG1044 70 LALIVVDNPYLAFAKLLQLFYPPPAPAP-GI 99
|
|
| lpxD |
PRK00892 |
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional |
3-112 |
3.07e-03 |
|
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional
Pssm-ID: 234858 [Multi-domain] Cd Length: 343 Bit Score: 39.74 E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 3 PMTVRELLTATGGRLLGEeavAERTITGVETDSRAVhEGDL-FValrgertDGHRYIASALETGAAGCL-TEEVPQVLLP 80
Cdd:PRK00892 2 SLTLAELAELLGAELVGD---GDIEITGVASLEEAG-PGQIsFL-------ANPKYRKQLATTKAGAVIvSPDDAEFVPA 70
|
90 100 110
....*....|....*....|....*....|...
gi 524045452 81 GKFYIQVEDTMLAIGQVARA-YREKFPIPVIGI 112
Cdd:PRK00892 71 GNALLVVKNPYLAFARLAQLfDPPATPSPAAGI 103
|
|
| FolC |
COG0285 |
Folylpolyglutamate synthase/Dihydropteroate synthase [Coenzyme transport and metabolism]; ... |
153-365 |
4.82e-03 |
|
Folylpolyglutamate synthase/Dihydropteroate synthase [Coenzyme transport and metabolism]; Folylpolyglutamate synthase/Dihydropteroate synthase is part of the Pathway/BioSystem: Folate biosynthesis
Pssm-ID: 440054 [Multi-domain] Cd Length: 423 Bit Score: 39.32 E-value: 4.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 153 FRLTAQHQ--ICVLEMGMNhfGEIDyLTQIAPPDVAVITNIGDAHIENLGSR--------AGILQAKKE-IFHRMTPEGM 221
Cdd:COG0285 126 FLYFAEAPvdVAVLEVGLG--GRLD-ATNVIDPLVSVITSIGLDHTDFLGDTleeiarekAGIIKPGVPvVTGDQQPEAL 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 524045452 222 AVLNgDDAMlrplegELSPQVVFCGADRpaPYAAKEIRQLGSKGLRCRVITpkndfsVTVPALGGHMIY---PVLMACAI 298
Cdd:COG0285 203 EVIE-ERAA------ELGAPLYRAGRDF--SVEEREGAVFSYQGPGGEYED------LPLPLLGAHQAEnaaLALAALEA 267
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 524045452 299 GERFGM--TGEEMKAGI-EAFVPTkmRMNVIHQGDITILDDAYnaNPQSMRAALEILSQTEGAYR-AAVLG 365
Cdd:COG0285 268 LRELGLpiSEEAIREGLaNARWPG--RLEVLSRGPLVILDGAH--NPAGARALAETLKELFPFRKlHLVFG 334
|
|
| |
