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Conserved domains on  [gi|351060196|emb|CCD67825|]
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Seven TM Receptor [Caenorhabditis elegans]

Protein Classification

class R serpentine receptor( domain architecture ID 10563422)

class R serpentine receptor, also known as seven TM receptor (Str), belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 10-313 6.52e-89

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402099  Cd Length: 307  Bit Score: 268.94  E-value: 6.52e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196   10 SHVFTIVEFFASTFTNLILIFLTAFYVKNLFGTYKRMVIYFSTLGIVFSALEITAKPFSHNYNGSLLYF---STSELPET 86
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFvdlKDLGLSKS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196   87 FVSLLMSSWSAFYIIVVAFIAVQFVYRYLCLTNYNATKKFDGVKTVFWIIYPLVPGAFYTISMNFLCAADEYSDSYVQAT 166
Cdd:pfam10326  81 VGQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196  167 ISKNYGLEVSKLPRYSMIAFS--ADGS--LRWNTVIYLIIGISSISFHYFIIIVCCYKMHISMKIELAKFSVKNQTLHRQ 242
Cdd:pfam10326 161 LLENYNLDIDEVAYVGPVYYPtdENGSkvIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQ 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 351060196  243 FFKALIVQIIGPTIFLIIPTIPIFFAPLLSpilkIDVDWQTGNLFALVGFNAPFDSIAFMLIVSEYKTIVK 313
Cdd:pfam10326 241 LFKALVIQTLIPTILMYIPVGILFLLPLFN----IEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 10-313 6.52e-89

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 268.94  E-value: 6.52e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196   10 SHVFTIVEFFASTFTNLILIFLTAFYVKNLFGTYKRMVIYFSTLGIVFSALEITAKPFSHNYNGSLLYF---STSELPET 86
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFvdlKDLGLSKS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196   87 FVSLLMSSWSAFYIIVVAFIAVQFVYRYLCLTNYNATKKFDGVKTVFWIIYPLVPGAFYTISMNFLCAADEYSDSYVQAT 166
Cdd:pfam10326  81 VGQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196  167 ISKNYGLEVSKLPRYSMIAFS--ADGS--LRWNTVIYLIIGISSISFHYFIIIVCCYKMHISMKIELAKFSVKNQTLHRQ 242
Cdd:pfam10326 161 LLENYNLDIDEVAYVGPVYYPtdENGSkvIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQ 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 351060196  243 FFKALIVQIIGPTIFLIIPTIPIFFAPLLSpilkIDVDWQTGNLFALVGFNAPFDSIAFMLIVSEYKTIVK 313
Cdd:pfam10326 241 LFKALVIQTLIPTILMYIPVGILFLLPLFN----IEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 10-313 6.52e-89

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 268.94  E-value: 6.52e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196   10 SHVFTIVEFFASTFTNLILIFLTAFYVKNLFGTYKRMVIYFSTLGIVFSALEITAKPFSHNYNGSLLYF---STSELPET 86
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFvdlKDLGLSKS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196   87 FVSLLMSSWSAFYIIVVAFIAVQFVYRYLCLTNYNATKKFDGVKTVFWIIYPLVPGAFYTISMNFLCAADEYSDSYVQAT 166
Cdd:pfam10326  81 VGQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196  167 ISKNYGLEVSKLPRYSMIAFS--ADGS--LRWNTVIYLIIGISSISFHYFIIIVCCYKMHISMKIELAKFSVKNQTLHRQ 242
Cdd:pfam10326 161 LLENYNLDIDEVAYVGPVYYPtdENGSkvIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQ 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 351060196  243 FFKALIVQIIGPTIFLIIPTIPIFFAPLLSpilkIDVDWQTGNLFALVGFNAPFDSIAFMLIVSEYKTIVK 313
Cdd:pfam10326 241 LFKALVIQTLIPTILMYIPVGILFLLPLFN----IEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
 21-309 9.57e-18

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 82.29  E-value: 9.57e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196   21 STFTNLILIFLTAFYVKNLFGTYKRMVIYFSTLGIVFSALEITAKPFSHNYNGSLLYFST-------SELPETFVSLLMS 93
Cdd:pfam10319  18 SFIVNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFVVFVSdgpffeySELGQHALSARCS 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196   94 SWSAFYiivvAFIAVQFVYRYLCLTNYNAT-KKFDGVKTVFWIIYPLVPGAFYTISMNFLCAADEYSDSYVQATISKNYG 172
Cdd:pfam10319  98 FISASY----AVLLIHFIYRYLVLFNPQLTrHYFRPWGILISILFFLFHGSVWTAICYFLLRANDEIRDYIREDFRETYG 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196  173 LEVSKLPRYSMIAFSADGSLRWNTVIYLII--GISSISFHYFIIIvcCYKMHISMKIELAKFSVKNQTLHRQFFKALIVQ 250
Cdd:pfam10319 174 VDSMDINMLGALYWEASDETVFRSWLGILLltVISVYSIILYIVL--GYKIMRKLNKMSVTMSKKTKRLQKQLLKALIVQ 251

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196  251 IIGPTIFLIIPTIPIFFapllSPILKIDVDWQTGNLFA-LVGFNAPFDSIAFMLIVSEYK 309
Cdd:pfam10319 252 TIIPICISFSPCVLAWY----SPIFGIDLGRWNNYLEViALSAFPFIDPLAIILCLPVYR 307
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 11-263 1.60e-04

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 42.92  E-value: 1.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196   11 HVFTIVEFFASTFTNLILIFLTAFYVKNLFGTYKRMVIYFSTLGIVFSALEITA--------KPFSHNYNGSLLYFStse 82
Cdd:pfam10317   2 SIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTqqriipngVSMALISYGPCKYFG--- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196   83 lpETFVSLLMSSWSAFYIIVVAFIAVQFVYRYLCLTNYNATKKfdGVKTVFWIIYPlvPGAFYTISMnFLCAADEYSDSY 162
Cdd:pfam10317  79 --PWFCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRK--KLILLIIIHYI--PSLSQLIVI-FLSPTDFLPVEA 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196  163 VQATISKNYGLEVsklprYSMIAFSADGSLRwNTVIYLIIGISSISFhYFIIIVCCYKMHISMKIELAKFSVKNQTLHRQ 242
Cdd:pfam10317 152 LTKELHPNYNLTD-----YTVTGFSDLQSFP-ALINTLIMTIPVFPI-PIIILILRRKILKLLNSNSVNMSPTTKAQHRQ 224

                         250       260
                  ....*....|....*....|.
gi 351060196  243 FFKALIVQIIGPTIFLIIPTI 263
Cdd:pfam10317 225 LIKGLTIQALLPLFSYIPGVT 245
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 97-268 6.10e-04

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 40.99  E-value: 6.10e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196   97 AFYIIVVAFIAVQFVYRYLCLTNYNATKKFDGVKTVFWIIYPLVPGAFYTISMNFLcaadEYSDSYVQATISKNYGLEVS 176
Cdd:pfam10318  94 TSLALVGVSIILLFENRYSILFTNKKRITWKKTRVLYLIFNYIIALLFLIPIYLNI----PDQEAAKLKVLKKLPCLPPE 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 351060196  177 KLPRYSMIAFSADGslrWNTVIYLIIGISSISFHYFIIIVCC-YKMHISMKIELakfSVKNQTLHRQFFKALIVQIIGPT 255
Cdd:pfam10318 170 FFDNPPVFVLAIDS---TYFLICIVLLILILIIQILFFVFLTiYYLFKSVKSSL---SKKTRKLQKKFFIALIIQVSIPL 243

                         170
                  ....*....|...
gi 351060196  256 IFLIIPTIPIFFA 268
Cdd:pfam10318 244 IVILIPLIYILFS 256
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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