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Conserved domains on  [gi|257711415|emb|CBD25699|]
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unnamed protein product [Arabidopsis thaliana]

Protein Classification

disease resistance family protein( domain architecture ID 1000118)

disease resistance family protein similar to Nicotiana glutinosa TMV resistance protein N; resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via a direct or indirect interaction with this avirulence protein

Gene Ontology:  GO:0006952

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PLN03210 super family cl33662
Resistant to P. syringae 6; Provisional
 16-766 0e+00

Resistant to P. syringae 6; Provisional


The actual alignment was detected with superfamily member PLN03210:

Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 894.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415   16 YHVFPSFCGEDVRRNFLSHLHKELQHNGIDAFKDGGIKRSRSIWPELKQAIWESKIFIVVLSKNYAGSCWCLDELVEIME 95
Cdd:PLN03210   13 YDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELLEIVR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415   96 CREVVGKTLVPIFYDVDPSSVRKQTGDFGKAFDKICDVRTEEERQRWRQALTNVGNIAGECSSKWDNDAKMIEKIVAYVS 175
Cdd:PLN03210   93 CKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIANDVL 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  176 EELFcFTSSTDFEDLLGLEAHVANLKSMLGLESNEVKMIGVWGPAGIGKTTITRILYNQLSSSndddFQLFIFMENV--- 252
Cdd:PLN03210  173 GKLN-LTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRMVGIWGSSGIGKTTIARALFSRLSRQ----FQSSVFIDRAfis 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  253 --KGSYRRKEIDGYSMKLHLRERFLSEITTQRKIKVSHLGVAQERLKNQKALIVLDDVDELEQLRALADQTQWVGNGTRI 330
Cdd:PLN03210  248 ksMEIYSSANPDDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSRI 327

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  331 LVTTEDRQLLKAHGITHVYEVDYPSRDEALKILCQCAFGKNSAPEGYNDLAVEVVELAGYLPLGLSVLGASLRGMSKKEW 410
Cdd:PLN03210  328 IVITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKEDW 407

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  411 INALPRLRTSLNGKIEKLLRVCYEGL-DEKDKAIFLHIACLFNGKNVDRVKLLLAKSALDVEFGLKVLVDRSLIHIDADg 489
Cdd:PLN03210  408 MDMLPRLRNGLDGKIEKTLRVSYDGLnNKKDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLIHVRED- 486

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  490 YIVMHCLLQQLGKEITRGQClDEPGKRKFLVDSLEISDVLADETGTETVLGISLDMSEIeDQVYVSEKAFEKMPNLQFLW 569
Cdd:PLN03210  487 IVEMHSLLQEMGKEIVRAQS-NEPGEREFLVDAKDICDVLEDNTGTKKVLGITLDIDEI-DELHIHENAFKGMRNLLFLK 564

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  570 LYKNFPDEA--VKLYLPHGLDYLPRKLRLLHWDSYPKKCLPSKFRPEFLVELTMRDSKLEKLWEGIQPLKSLKRMDLSAS 647
Cdd:PLN03210  565 FYTKKWDQKkeVRWHLPEGFDYLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGS 644

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  648 TKIKDIPNLSRATNLEKLYLRFCKNLVIVPSScLQNLHKLKVLDMSCCIKLKSLPDNINLKSLSVLNMRGCSKLNNFPLI 727
Cdd:PLN03210  645 KNLKEIPDLSMATNLETLKLSDCSSLVELPSS-IQYLNKLEDLDMSRCENLEILPTGINLKSLYRLNLSGCSRLKSFPDI 723

                         730       740       750
                  ....*....|....*....|....*....|....*....
gi 257711415  728 STQIQFMSLGETAIEKVPSVIKLcSRLVSLEMAGCKNLK 766
Cdd:PLN03210  724 STNISWLDLDETAIEEFPSNLRL-ENLDELILCEMKSEK 761
 
Name Accession Description Interval E-value
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 16-766 0e+00

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 894.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415   16 YHVFPSFCGEDVRRNFLSHLHKELQHNGIDAFKDGGIKRSRSIWPELKQAIWESKIFIVVLSKNYAGSCWCLDELVEIME 95
Cdd:PLN03210   13 YDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELLEIVR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415   96 CREVVGKTLVPIFYDVDPSSVRKQTGDFGKAFDKICDVRTEEERQRWRQALTNVGNIAGECSSKWDNDAKMIEKIVAYVS 175
Cdd:PLN03210   93 CKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIANDVL 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  176 EELFcFTSSTDFEDLLGLEAHVANLKSMLGLESNEVKMIGVWGPAGIGKTTITRILYNQLSSSndddFQLFIFMENV--- 252
Cdd:PLN03210  173 GKLN-LTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRMVGIWGSSGIGKTTIARALFSRLSRQ----FQSSVFIDRAfis 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  253 --KGSYRRKEIDGYSMKLHLRERFLSEITTQRKIKVSHLGVAQERLKNQKALIVLDDVDELEQLRALADQTQWVGNGTRI 330
Cdd:PLN03210  248 ksMEIYSSANPDDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSRI 327

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  331 LVTTEDRQLLKAHGITHVYEVDYPSRDEALKILCQCAFGKNSAPEGYNDLAVEVVELAGYLPLGLSVLGASLRGMSKKEW 410
Cdd:PLN03210  328 IVITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKEDW 407

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  411 INALPRLRTSLNGKIEKLLRVCYEGL-DEKDKAIFLHIACLFNGKNVDRVKLLLAKSALDVEFGLKVLVDRSLIHIDADg 489
Cdd:PLN03210  408 MDMLPRLRNGLDGKIEKTLRVSYDGLnNKKDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLIHVRED- 486

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  490 YIVMHCLLQQLGKEITRGQClDEPGKRKFLVDSLEISDVLADETGTETVLGISLDMSEIeDQVYVSEKAFEKMPNLQFLW 569
Cdd:PLN03210  487 IVEMHSLLQEMGKEIVRAQS-NEPGEREFLVDAKDICDVLEDNTGTKKVLGITLDIDEI-DELHIHENAFKGMRNLLFLK 564

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  570 LYKNFPDEA--VKLYLPHGLDYLPRKLRLLHWDSYPKKCLPSKFRPEFLVELTMRDSKLEKLWEGIQPLKSLKRMDLSAS 647
Cdd:PLN03210  565 FYTKKWDQKkeVRWHLPEGFDYLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGS 644

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  648 TKIKDIPNLSRATNLEKLYLRFCKNLVIVPSScLQNLHKLKVLDMSCCIKLKSLPDNINLKSLSVLNMRGCSKLNNFPLI 727
Cdd:PLN03210  645 KNLKEIPDLSMATNLETLKLSDCSSLVELPSS-IQYLNKLEDLDMSRCENLEILPTGINLKSLYRLNLSGCSRLKSFPDI 723

                         730       740       750
                  ....*....|....*....|....*....|....*....
gi 257711415  728 STQIQFMSLGETAIEKVPSVIKLcSRLVSLEMAGCKNLK 766
Cdd:PLN03210  724 STNISWLDLDETAIEEFPSNLRL-ENLDELILCEMKSEK 761
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
 16-178 7.12e-62

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 205.29  E-value: 7.12e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415   16 YHVFPSFCGEDVRRNFLSHLHKELQHNGIDAFKDG-GIKRSRSIWPELKQAIWESKIFIVVLSKNYAGSCWCLDELVEIM 94
Cdd:pfam01582   1 YDVFLSFRGSDTREWFVSHLLKELKQKGIKLFIDDrDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415   95 ECREVVGKTLVPIFYDVDPSSVRKQTGDFGKAFDKICDVRTEEERQRWRQALTNVGNIagECSSKWDNDAKMIEKIVAYV 174
Cdd:pfam01582  81 ECALDLGQKVIPIFYEVDPSDVRKQTGSFGKAFKKHKKVLTEEKVLKWRGALNEVANI--WHSKSVSDESKFWKKIAYDI 158


                  ....
gi 257711415  175 SEEL 178
Cdd:pfam01582 159 SNKL 162
TIR smart00255
Toll - interleukin 1 - resistance;
16-152 2.58e-39

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 142.08  E-value: 2.58e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415    16 YHVFPSFCG-EDVRRNFLSHLHKELQHNGIDAFKDGGIKRSrSIWPELKQAIWESKIFIVVLSKNYAGSCWCLDELVEIM 94
Cdd:smart00255   2 YDVFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFEPGG-GDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAAL 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415    95 ECREV-VGKTLVPIFYDVDPSSVRKQTGDFGKAFDKICDVRTEEE-RQRWRQALTNVGNI 152
Cdd:smart00255  81 ENALEeGGLRVIPIFYEVIPSDVRKQPGKFRKVFKKNYLKWPEDEkEQFWKKALYAVPSK 140
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
616-769 1.50e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 73.43  E-value: 1.50e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 616 LVELTMRDSKLEKLWEGIQPLKSLKRMDLSaSTKIKDIPN-LSRATNLEKLYLRFCKnLVIVPSScLQNLHKLKVLDMSC 694
Cdd:COG4886  115 LESLDLSGNQLTDLPEELANLTNLKELDLS-NNQLTDLPEpLGNLTNLKSLDLSNNQ-LTDLPEE-LGNLTNLKELDLSN 191

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 257711415 695 CiKLKSLPDNI-NLKSLSVLNMRGCsKLNNFPL-IS--TQIQFMSLGETAIEKVPSVIKLcSRLVSLEMAGCKnLKTLP 769
Cdd:COG4886  192 N-QITDLPEPLgNLTNLEELDLSGN-QLTDLPEpLAnlTNLETLDLSNNQLTDLPELGNL-TNLEELDLSNNQ-LTDLP 266
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 302-421 1.61e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 45.29  E-value: 1.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 302 LIVLDDVDELEQLRALADQtqwvGNGTRILVTTEDRQLlkAHGITHVYEVDYPSRDEALKILCQCAFGKNSApegynDLA 381
Cdd:NF040586 112 LLVFDNADDPEDLRDLLPT----GGPGHVLITSRNRAW--SEVAAATLEVDVFSREESVALLRRRVPGLTSE-----EDA 180

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 257711415 382 VEVVELAGYLPLGLSVLGASL--RGMSKKEWINALPRLRTSL 421
Cdd:NF040586 181 DRLAEALGDLPLALEQAAAWLaeTGMPVDEYLRLLDEQATAA 222
 
Name Accession Description Interval E-value
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 16-766 0e+00

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 894.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415   16 YHVFPSFCGEDVRRNFLSHLHKELQHNGIDAFKDGGIKRSRSIWPELKQAIWESKIFIVVLSKNYAGSCWCLDELVEIME 95
Cdd:PLN03210   13 YDVFPSFSGEDVRITFLSHFLKELDRKLIIAFKDNEIERSQSLDPELKQAIRDSRIAVVVFSKNYASSSWCLNELLEIVR 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415   96 CREVVGKTLVPIFYDVDPSSVRKQTGDFGKAFDKICDVRTEEERQRWRQALTNVGNIAGECSSKWDNDAKMIEKIVAYVS 175
Cdd:PLN03210   93 CKEELGQLVIPVFYGLDPSHVRKQTGDFGEAFEKTCQNKTEDEKIQWKQALTDVANILGYHSQNWPNEAKMIEEIANDVL 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  176 EELFcFTSSTDFEDLLGLEAHVANLKSMLGLESNEVKMIGVWGPAGIGKTTITRILYNQLSSSndddFQLFIFMENV--- 252
Cdd:PLN03210  173 GKLN-LTPSNDFEDFVGIEDHIAKMSSLLHLESEEVRMVGIWGSSGIGKTTIARALFSRLSRQ----FQSSVFIDRAfis 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  253 --KGSYRRKEIDGYSMKLHLRERFLSEITTQRKIKVSHLGVAQERLKNQKALIVLDDVDELEQLRALADQTQWVGNGTRI 330
Cdd:PLN03210  248 ksMEIYSSANPDDYNMKLHLQRAFLSEILDKKDIKIYHLGAMEERLKHRKVLIFIDDLDDQDVLDALAGQTQWFGSGSRI 327

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  331 LVTTEDRQLLKAHGITHVYEVDYPSRDEALKILCQCAFGKNSAPEGYNDLAVEVVELAGYLPLGLSVLGASLRGMSKKEW 410
Cdd:PLN03210  328 IVITKDKHFLRAHGIDHIYEVCLPSNELALEMFCRSAFKKNSPPDGFMELASEVALRAGNLPLGLNVLGSYLRGRDKEDW 407

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  411 INALPRLRTSLNGKIEKLLRVCYEGL-DEKDKAIFLHIACLFNGKNVDRVKLLLAKSALDVEFGLKVLVDRSLIHIDADg 489
Cdd:PLN03210  408 MDMLPRLRNGLDGKIEKTLRVSYDGLnNKKDKAIFRHIACLFNGEKVNDIKLLLANSDLDVNIGLKNLVDKSLIHVRED- 486

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  490 YIVMHCLLQQLGKEITRGQClDEPGKRKFLVDSLEISDVLADETGTETVLGISLDMSEIeDQVYVSEKAFEKMPNLQFLW 569
Cdd:PLN03210  487 IVEMHSLLQEMGKEIVRAQS-NEPGEREFLVDAKDICDVLEDNTGTKKVLGITLDIDEI-DELHIHENAFKGMRNLLFLK 564

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  570 LYKNFPDEA--VKLYLPHGLDYLPRKLRLLHWDSYPKKCLPSKFRPEFLVELTMRDSKLEKLWEGIQPLKSLKRMDLSAS 647
Cdd:PLN03210  565 FYTKKWDQKkeVRWHLPEGFDYLPPKLRLLRWDKYPLRCMPSNFRPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGS 644

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  648 TKIKDIPNLSRATNLEKLYLRFCKNLVIVPSScLQNLHKLKVLDMSCCIKLKSLPDNINLKSLSVLNMRGCSKLNNFPLI 727
Cdd:PLN03210  645 KNLKEIPDLSMATNLETLKLSDCSSLVELPSS-IQYLNKLEDLDMSRCENLEILPTGINLKSLYRLNLSGCSRLKSFPDI 723

                         730       740       750
                  ....*....|....*....|....*....|....*....
gi 257711415  728 STQIQFMSLGETAIEKVPSVIKLcSRLVSLEMAGCKNLK 766
Cdd:PLN03210  724 STNISWLDLDETAIEEFPSNLRL-ENLDELILCEMKSEK 761
TIR pfam01582
TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular ...
 16-178 7.12e-62

TIR domain; The Toll/interleukin-1 receptor (TIR) homology domain is an intracellular signalling domain found in MyD88, interleukin 1 receptor and the Toll receptor. It contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins thought to be involved in resistance to disease. When activated, TIR domains recruit cytoplasmic adaptor proteins MyD88 and TOLLIP (Toll interacting protein). In turn, these associate with various kinases to set off signalling cascades.


Pssm-ID: 396246 [Multi-domain]  Cd Length: 165  Bit Score: 205.29  E-value: 7.12e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415   16 YHVFPSFCGEDVRRNFLSHLHKELQHNGIDAFKDG-GIKRSRSIWPELKQAIWESKIFIVVLSKNYAGSCWCLDELVEIM 94
Cdd:pfam01582   1 YDVFLSFRGSDTREWFVSHLLKELKQKGIKLFIDDrDLEPGEAIAPELLSAIEKSRRSVVVLSPNYASSGWCLDELVKIL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415   95 ECREVVGKTLVPIFYDVDPSSVRKQTGDFGKAFDKICDVRTEEERQRWRQALTNVGNIagECSSKWDNDAKMIEKIVAYV 174
Cdd:pfam01582  81 ECALDLGQKVIPIFYEVDPSDVRKQTGSFGKAFKKHKKVLTEEKVLKWRGALNEVANI--WHSKSVSDESKFWKKIAYDI 158


                  ....
gi 257711415  175 SEEL 178
Cdd:pfam01582 159 SNKL 162
TIR smart00255
Toll - interleukin 1 - resistance;
16-152 2.58e-39

Toll - interleukin 1 - resistance;


Pssm-ID: 214587 [Multi-domain]  Cd Length: 140  Bit Score: 142.08  E-value: 2.58e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415    16 YHVFPSFCG-EDVRRNFLSHLHKELQHNGIDAFKDGGIKRSrSIWPELKQAIWESKIFIVVLSKNYAGSCWCLDELVEIM 94
Cdd:smart00255   2 YDVFISYSGkEDVRNEFLSHLLEKLRGYGLCVFIDDFEPGG-GDLEEIDEAIEKSRIAIVVLSPNYAESEWCLDELVAAL 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415    95 ECREV-VGKTLVPIFYDVDPSSVRKQTGDFGKAFDKICDVRTEEE-RQRWRQALTNVGNI 152
Cdd:smart00255  81 ENALEeGGLRVIPIFYEVIPSDVRKQPGKFRKVFKKNYLKWPEDEkEQFWKKALYAVPSK 140
NB-ARC pfam00931
NB-ARC domain;
193-434 2.17e-17

NB-ARC domain;


Pssm-ID: 395745 [Multi-domain]  Cd Length: 245  Bit Score: 82.43  E-value: 2.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  193 LEAHVANLKSMLgLESNEVKMIGVWGPAGIGKTTITRILYNQLSSSnDDDFQLFIFMEnVKGSYRRKEIdgysMKLHLRE 272
Cdd:pfam00931   1 REDMVEKVIGKL-SEKDEPGIVGIHGMGGVGKTTLAAQIFNDFDEV-EGHFDSVAWVV-VSKTFTISTL----QQTILQN 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  273 RFLSEITTQRKIKVSHLGVAQERLKNQKALIVLDDVDELEQLRALADQTQWVGNGTRILVTTEDRQLLKAHGITH-VYEV 351
Cdd:pfam00931  74 LGLSEDDWDNKEEGELARKIRRALLTKRFLLVLDDVWDEEDWDKIGIPLPDRENGCRVLLTTRSEEVAGRVGGPSdPHEV 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  352 DYPSRDEALKILCQCAFGKNS-APEGYNDLAVEVVELAGYLPLGLSVLGASLRgmSKK---EWINALPRLRTSLNG---- 423
Cdd:pfam00931 154 ELLEPDEAWELFENKVFPKTLgECELLEDVAKEIVEKCRGLPLALKVLGGLLS--CKKtveEWKHVYDVLQSELKSnsys 231

                         250
                  ....*....|...
gi 257711415  424 --KIEKLLRVCYE 434
Cdd:pfam00931 232 lnSVRSILQLSYE 244
TIR_2 pfam13676
TIR domain; This is a family of Toll-like receptors.
 18-113 1.30e-13

TIR domain; This is a family of Toll-like receptors.


Pssm-ID: 463954 [Multi-domain]  Cd Length: 118  Bit Score: 67.73  E-value: 1.30e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415   18 VFPSFCGEDvrRNFLSHLHKELQHNGIDAFKD-GGIKRSRSIWPELKQAIWESKIFIVVLSKNYAGSCWCLDELVEIMEC 96
Cdd:pfam13676   1 VFISYAGED--RAWAEWLADALEAAGYRVWLDrWDIRPGDDWVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWEAALAD 78

                          90
                  ....*....|....*..
gi 257711415   97 REvVGKTLVPIFYDVDP 113
Cdd:pfam13676  79 PE-GRKRLIPVRLECDL 94
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
616-769 1.50e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 73.43  E-value: 1.50e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 616 LVELTMRDSKLEKLWEGIQPLKSLKRMDLSaSTKIKDIPN-LSRATNLEKLYLRFCKnLVIVPSScLQNLHKLKVLDMSC 694
Cdd:COG4886  115 LESLDLSGNQLTDLPEELANLTNLKELDLS-NNQLTDLPEpLGNLTNLKSLDLSNNQ-LTDLPEE-LGNLTNLKELDLSN 191

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 257711415 695 CiKLKSLPDNI-NLKSLSVLNMRGCsKLNNFPL-IS--TQIQFMSLGETAIEKVPSVIKLcSRLVSLEMAGCKnLKTLP 769
Cdd:COG4886  192 N-QITDLPEPLgNLTNLEELDLSGN-QLTDLPEpLAnlTNLETLDLSNNQLTDLPELGNL-TNLEELDLSNNQ-LTDLP 266
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
557-717 5.81e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 62.26  E-value: 5.81e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 557 KAFEKMPNLQFLWLYKNfpdeavKL-YLPHGLDYLPrKLRLLHWDSYPKKCLPSKFRP-EFLVELTMRDSKLEKLWEGIQ 634
Cdd:COG4886  130 EELANLTNLKELDLSNN------QLtDLPEPLGNLT-NLKSLDLSNNQLTDLPEELGNlTNLKELDLSNNQITDLPEPLG 202

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 635 PLKSLKRMDLSaSTKIKDIP-NLSRATNLEKLYLRFCKnLVIVPSscLQNLHKLKVLDMSCCiKLKSLPDNINLKSLSVL 713
Cdd:COG4886  203 NLTNLEELDLS-GNQLTDLPePLANLTNLETLDLSNNQ-LTDLPE--LGNLTNLEELDLSNN-QLTDLPPLANLTNLKTL 277


                 ....
gi 257711415 714 NMRG 717
Cdd:COG4886  278 DLSN 281
PLN03194 PLN03194
putative disease resistance protein; Provisional
 18-146 7.85e-09

putative disease resistance protein; Provisional


Pssm-ID: 215626 [Multi-domain]  Cd Length: 187  Bit Score: 55.98  E-value: 7.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  18 VFPSFCGEDVRRNFLSHLHKELQHNGIDAFKDG-GIKRSRSIWPELKQAIWESKIFIVVLSKNYAGSCWCLDELVEIMEC 96
Cdd:PLN03194  29 VFINHRGIDTKRTIATLLYDHLSRLNLRPFLDNkNMKPGDKLFDKINSAIRNCKVGVAVFSPRYCESYFCLHELALIMES 108

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 257711415  97 REVVgktlVPIFYDVDPSSVRKQTgdfgkafDKICdvrTEEERQRWRQAL 146
Cdd:PLN03194 109 KKRV----IPIFCDVKPSQLRVVD-------NGTC---PDEEIRRFNWAL 144
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
633-768 1.85e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 57.25  E-value: 1.85e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 633 IQPLKSLKRMDLSastkikDIPNLSRATNLEKLYLRFCKnLVIVPSScLQNLHKLKVLDMSCCiKLKSLPDNI-NLKSLS 711
Cdd:COG4886   92 LGDLTNLTELDLS------GNEELSNLTNLESLDLSGNQ-LTDLPEE-LANLTNLKELDLSNN-QLTDLPEPLgNLTNLK 162

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 257711415 712 VLNMRGCsKLNNFPL-IS--TQIQFMSLGETAIEKVPSVIKLCSRLVSL------------EMAGCKNLKTL 768
Cdd:COG4886  163 SLDLSNN-QLTDLPEeLGnlTNLKELDLSNNQITDLPEPLGNLTNLEELdlsgnqltdlpePLANLTNLETL 233
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
557-732 8.62e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 55.32  E-value: 8.62e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 557 KAFEKMPNLQFLWLYKNfpdeavKL-YLPHGLDYLPRklrllhwdsypkkclpskfrpefLVELTMRDSKLEKLWEGIQP 635
Cdd:COG4886  176 EELGNLTNLKELDLSNN------QItDLPEPLGNLTN-----------------------LEELDLSGNQLTDLPEPLAN 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 636 LKSLKRMDLSaSTKIKDIPNLSRATNLEKLYLRFCKnlvIVPSSCLQNLHKLKVLDMSCC----IKLKSLPDNINLKSLS 711
Cdd:COG4886  227 LTNLETLDLS-NNQLTDLPELGNLTNLEELDLSNNQ---LTDLPPLANLTNLKTLDLSNNqltdLKLKELELLLGLNSLL 302

                        170       180
                 ....*....|....*....|.
gi 257711415 712 VLNMRGCSKLNNFPLISTQIQ 732
Cdd:COG4886  303 LLLLLLNLLELLILLLLLTTL 323
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
622-768 1.67e-06

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 51.09  E-value: 1.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 622 RDSKLEKLWEGIQPLKSLKRMDLSASTKIKDIPNLSRATNLEKLYLRFCKNlvivpsscLQNLHKLKVLDMSCCiKLKSL 701
Cdd:COG4886   58 RDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEE--------LSNLTNLESLDLSGN-QLTDL 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 702 PDNI-NLKSLSVLNMRGCsKLNNFPL-IS--TQIQFMSLGETAIEKVPSVIKLCSRLVSL------------EMAGCKNL 765
Cdd:COG4886  129 PEELaNLTNLKELDLSNN-QLTDLPEpLGnlTNLKSLDLSNNQLTDLPEELGNLTNLKELdlsnnqitdlpePLGNLTNL 207


                 ...
gi 257711415 766 KTL 768
Cdd:COG4886  208 EEL 210
LRR_3 pfam07725
Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the ...
 615-634 3.61e-06

Leucine Rich Repeat; This Pfam entry includes some LRRs that fail to be detected by the pfam00560 model.


Pssm-ID: 429621 [Multi-domain]  Cd Length: 20  Bit Score: 43.87  E-value: 3.61e-06
                          10        20
                  ....*....|....*....|
gi 257711415  615 FLVELTMRDSKLEKLWEGIQ 634
Cdd:pfam07725   1 NLVELNMPYSKLEKLWEGVK 20
COG4916 COG4916
Uncharacterized conserved protein [Function unknown];
16-141 7.22e-06

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443944 [Multi-domain]  Cd Length: 236  Bit Score: 48.19  E-value: 7.22e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415  16 YHVFPSFCGEDvrRNFLSHLHKELQHNGIDAFKDggIKRSRSIW----PELKQAIW--ESKIFIVVLSKNYAGSCWCLDE 89
Cdd:COG4916    1 YDVALSFAGED--REFVERVAEALKARGIKVFYD--ENEEAELWgkdlDEYLQDIYrsESRFVVVFLSKDYVEKKWTGLE 76

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 257711415  90 LVEIMEcREVVGKT--LVPIFYD-VDPSSVRKQTG--DFGKafdkicdvRTEEERQR 141
Cdd:COG4916   77 RRAALA-RAMQRKKeyILPIRLDdTEIPGILATIGyiDLRN--------RTPEEIAD 124
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 302-421 1.61e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 45.29  E-value: 1.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 302 LIVLDDVDELEQLRALADQtqwvGNGTRILVTTEDRQLlkAHGITHVYEVDYPSRDEALKILCQCAFGKNSApegynDLA 381
Cdd:NF040586 112 LLVFDNADDPEDLRDLLPT----GGPGHVLITSRNRAW--SEVAAATLEVDVFSREESVALLRRRVPGLTSE-----EDA 180

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 257711415 382 VEVVELAGYLPLGLSVLGASL--RGMSKKEWINALPRLRTSL 421
Cdd:NF040586 181 DRLAEALGDLPLALEQAAAWLaeTGMPVDEYLRLLDEQATAA 222
NACHT COG5635
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
191-334 2.57e-04

Predicted NTPase, NACHT family domain [Signal transduction mechanisms];


Pssm-ID: 444362 [Multi-domain]  Cd Length: 935  Bit Score: 44.80  E-value: 2.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 191 LGLEAHVANLKSMLGLESNEVKMIgVWGPAGIGKTTITRILYNQLSSSNDDDFQ---LFIFMENVKGSYrrkeidgysmk 267
Cdd:COG5635  161 LNLLERIESLKRLELLEAKKKRLL-ILGEPGSGKTTLLRYLALELAERYLDAEDpipILIELRDLAEEA----------- 228

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 257711415 268 lHLRERFLSEITTQRKIKVSHLgvaQERLKNQKALIVLDDVDELEQLRALADQTQWVGN------GTRILVTT 334
Cdd:COG5635  229 -SLEDLLAEALEKRGGEPEDAL---ERLLRNGRLLLLLDGLDEVPDEADRDEVLNQLRRflerypKARVIITS 297
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
607-769 6.91e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 39.53  E-value: 6.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 607 LPSKFRPEFLVELTMRDSKLEKLWEGIQPLKSLKRMDLSASTKIKDIPNLSRATNLEKLYLRFCKNLVIVPSScLQNLHK 686
Cdd:COG4886   19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTD-LGDLTN 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257711415 687 LKVLDMSCCIKLKslpdniNLKSLSVLNMRGCsKLNNFPL-IS--TQIQFMSLGETAIEKVPSVIKLCSRLVSLEMAGCK 763
Cdd:COG4886   98 LTELDLSGNEELS------NLTNLESLDLSGN-QLTDLPEeLAnlTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQ 170


                 ....*.
gi 257711415 764 nLKTLP 769
Cdd:COG4886  171 -LTDLP 175
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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