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Conserved domains on  [gi|219926173|emb|CAW75959|]
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unnamed protein product [Arabidopsis thaliana]

Protein Classification

PP2 family F-box protein( domain architecture ID 17779824)

PP2 (Phloem protein 2) family F-box protein is a component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins

CATH:  1.20.1280.50
Gene Ontology:  GO:0030246|GO:0019005|GO:0005515
PubMed:  12529520|31898225|11178263|11077244
SCOP:  4001927

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PP2 pfam14299
Phloem protein 2; Phloem protein 2 (PP2) is one of the most abundant and enigmatic proteins in ...
 94-280 5.60e-61

Phloem protein 2; Phloem protein 2 (PP2) is one of the most abundant and enigmatic proteins in the phloem sap. PP2 is translocated in the assimilate stream where its lectin activity or RNA-binding properties can exert effects over long distances.


:

Pssm-ID: 464128  Cd Length: 151  Bit Score: 190.11  E-value: 5.60e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219926173   94 KISYVLSARDISITHSDHASYWSWSNVSDSRFSESAELIITDRLEIEGKIQTRVLSANTRYGAYLIVKVTKGAYGLDLVP 173
Cdd:pfam14299   1 KKCYMLSARALSITWGDDPRYWRWIPLPESRFSEVAELLQVCWLEIRGKIDTRMLSPGTTYSAYFVFKLGDSSYGWDDVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219926173  174 AETSIksKNGQISKSATYLccldekkqqmkrlfygnreermamtveavggdgkrREPKCRDDGWMEIELGEFETRE-GED 252
Cdd:pfam14299  81 VEFSV--SVGSSSKRFVCL-----------------------------------RRPKEREDGWMEIELGEFVVNEgGED 123

                         170       180
                  ....*....|....*....|....*...
gi 219926173  253 DEVNMTLTEVKGYQLKGGILIDGIEVRP 280
Cdd:pfam14299 124 GEVEFSLYEVKGGHWKGGLIVEGIEIRP 151
F-box_AtSKIP3-like cd22162
F-box domain found in Arabidopsis thaliana SKP1-interacting partner 3 (AtSKIP3) and similar ...
 4-46 1.21e-12

F-box domain found in Arabidopsis thaliana SKP1-interacting partner 3 (AtSKIP3) and similar proteins; AtSKIP3, also called F-box protein SKIP3, F-box protein PP2-B9, or protein PHLOEM PROTEIN 2-LIKE B9, is a component of SCF (SKP1-cullin-F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. It interacts with SKP1A/ASK1. This subfamily also includes many other Arabidopsis thaliana protein PHLOEM PROTEIN 2-LIKE proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


:

Pssm-ID: 438933  Cd Length: 46  Bit Score: 61.06  E-value: 1.21e-12
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 219926173   4 LPEACIANILAFTSPADAFSSSEVSSVFRLAGDSDFVWEKFLP 46
Cdd:cd22162    4 LPEDCIALILSFTSPRDVCRLSAVSKTFRSAAESDVVWERFLP 46
 
Name Accession Description Interval E-value
PP2 pfam14299
Phloem protein 2; Phloem protein 2 (PP2) is one of the most abundant and enigmatic proteins in ...
 94-280 5.60e-61

Phloem protein 2; Phloem protein 2 (PP2) is one of the most abundant and enigmatic proteins in the phloem sap. PP2 is translocated in the assimilate stream where its lectin activity or RNA-binding properties can exert effects over long distances.


Pssm-ID: 464128  Cd Length: 151  Bit Score: 190.11  E-value: 5.60e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219926173   94 KISYVLSARDISITHSDHASYWSWSNVSDSRFSESAELIITDRLEIEGKIQTRVLSANTRYGAYLIVKVTKGAYGLDLVP 173
Cdd:pfam14299   1 KKCYMLSARALSITWGDDPRYWRWIPLPESRFSEVAELLQVCWLEIRGKIDTRMLSPGTTYSAYFVFKLGDSSYGWDDVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219926173  174 AETSIksKNGQISKSATYLccldekkqqmkrlfygnreermamtveavggdgkrREPKCRDDGWMEIELGEFETRE-GED 252
Cdd:pfam14299  81 VEFSV--SVGSSSKRFVCL-----------------------------------RRPKEREDGWMEIELGEFVVNEgGED 123

                         170       180
                  ....*....|....*....|....*...
gi 219926173  253 DEVNMTLTEVKGYQLKGGILIDGIEVRP 280
Cdd:pfam14299 124 GEVEFSLYEVKGGHWKGGLIVEGIEIRP 151
F-box_AtSKIP3-like cd22162
F-box domain found in Arabidopsis thaliana SKP1-interacting partner 3 (AtSKIP3) and similar ...
 4-46 1.21e-12

F-box domain found in Arabidopsis thaliana SKP1-interacting partner 3 (AtSKIP3) and similar proteins; AtSKIP3, also called F-box protein SKIP3, F-box protein PP2-B9, or protein PHLOEM PROTEIN 2-LIKE B9, is a component of SCF (SKP1-cullin-F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. It interacts with SKP1A/ASK1. This subfamily also includes many other Arabidopsis thaliana protein PHLOEM PROTEIN 2-LIKE proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438933  Cd Length: 46  Bit Score: 61.06  E-value: 1.21e-12
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 219926173   4 LPEACIANILAFTSPADAFSSSEVSSVFRLAGDSDFVWEKFLP 46
Cdd:cd22162    4 LPEDCIALILSFTSPRDVCRLSAVSKTFRSAAESDVVWERFLP 46
 
Name Accession Description Interval E-value
PP2 pfam14299
Phloem protein 2; Phloem protein 2 (PP2) is one of the most abundant and enigmatic proteins in ...
 94-280 5.60e-61

Phloem protein 2; Phloem protein 2 (PP2) is one of the most abundant and enigmatic proteins in the phloem sap. PP2 is translocated in the assimilate stream where its lectin activity or RNA-binding properties can exert effects over long distances.


Pssm-ID: 464128  Cd Length: 151  Bit Score: 190.11  E-value: 5.60e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219926173   94 KISYVLSARDISITHSDHASYWSWSNVSDSRFSESAELIITDRLEIEGKIQTRVLSANTRYGAYLIVKVTKGAYGLDLVP 173
Cdd:pfam14299   1 KKCYMLSARALSITWGDDPRYWRWIPLPESRFSEVAELLQVCWLEIRGKIDTRMLSPGTTYSAYFVFKLGDSSYGWDDVP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219926173  174 AETSIksKNGQISKSATYLccldekkqqmkrlfygnreermamtveavggdgkrREPKCRDDGWMEIELGEFETRE-GED 252
Cdd:pfam14299  81 VEFSV--SVGSSSKRFVCL-----------------------------------RRPKEREDGWMEIELGEFVVNEgGED 123

                         170       180
                  ....*....|....*....|....*...
gi 219926173  253 DEVNMTLTEVKGYQLKGGILIDGIEVRP 280
Cdd:pfam14299 124 GEVEFSLYEVKGGHWKGGLIVEGIEIRP 151
F-box_AtSKIP3-like cd22162
F-box domain found in Arabidopsis thaliana SKP1-interacting partner 3 (AtSKIP3) and similar ...
 4-46 1.21e-12

F-box domain found in Arabidopsis thaliana SKP1-interacting partner 3 (AtSKIP3) and similar proteins; AtSKIP3, also called F-box protein SKIP3, F-box protein PP2-B9, or protein PHLOEM PROTEIN 2-LIKE B9, is a component of SCF (SKP1-cullin-F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. It interacts with SKP1A/ASK1. This subfamily also includes many other Arabidopsis thaliana protein PHLOEM PROTEIN 2-LIKE proteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression.


Pssm-ID: 438933  Cd Length: 46  Bit Score: 61.06  E-value: 1.21e-12
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 219926173   4 LPEACIANILAFTSPADAFSSSEVSSVFRLAGDSDFVWEKFLP 46
Cdd:cd22162    4 LPEDCIALILSFTSPRDVCRLSAVSKTFRSAAESDVVWERFLP 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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