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Conserved domains on  [gi|219783558|emb|CAW43550|]
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unnamed protein product [Arabidopsis thaliana]

Protein Classification

triose-phosphate transporter family protein( domain architecture ID 1750314)

triose-phosphate transporter (TPT) family protein belongs to the drug/metabolite transporter (DMT) superfamily; similar to the well-characterized triose phosphate and sugar phosphate permeases of chloroplasts and its functionally uncharacterized homologs found in yeast and animals

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TPT_S35C2 super family cl40580
solute carrier family 35 member C2, member of the triose-phosphate transporter family; Solute ...
141-371 2.09e-60

solute carrier family 35 member C2, member of the triose-phosphate transporter family; Solute carrier family 35 member C2 (S35C2 or Slc35c2), also called ovarian cancer-overexpressed gene 1 protein (OVCOV1), is a member of the triose-phosphate transporter (TPT) family, which is part of the drug/metabolite transporter (DMT) superfamily. It may function either as a GDP-fucose transporter that competes with Slc35c1 (S35C1) for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells.


The actual alignment was detected with superfamily member cd21092:

Pssm-ID: 411044  Cd Length: 248  Bit Score: 196.34  E-value: 2.09e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 141 WRDYFVRVVPTALGTAMDINLSNESLVFISVTFATMCKSAAPIFLLLFAFAFRLESPSLKLFGIISVISAGVLLTVAKET 220
Cdd:cd21092    1 WSDYLKRVAPTGLASALDIGLSNWSFLFITVSLYTMTKSSAIIFILFFSLVFKLEKPRWSLVLVVLLIAGGLFMFTYKST 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 221 EFEFWGFVFVMLAAVMSGFRWCMTQVLLQKETFGLKNPFIFMSCVAPVMAIATGLLSLLLDPWSEFRDNKYF--DSGAHF 298
Cdd:cd21092   81 QFNLEGFILVLSASFLGGLRWTLAQLLMQKAELGLQNPIDMMYHLQPWMILGLLPLAIGFEGLHLATSEKLFrfHDSSVL 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 219783558 299 ARTCFLMLFGGALAFCMVLTEYVLVSVTSAVTVTIAGVVKEAVTIVVAVFYFHDEFTWLKGVGLMIIMVGVSL 371
Cdd:cd21092  161 LRTLGYLLLGAVLAFGLEFSEFLLVSKTSSLTLSIAGIFKEICTLLLAVHINGDHLSLLNWLGLVICLCGISL 233
 
Name Accession Description Interval E-value
TPT_S35C2 cd21092
solute carrier family 35 member C2, member of the triose-phosphate transporter family; Solute ...
141-371 2.09e-60

solute carrier family 35 member C2, member of the triose-phosphate transporter family; Solute carrier family 35 member C2 (S35C2 or Slc35c2), also called ovarian cancer-overexpressed gene 1 protein (OVCOV1), is a member of the triose-phosphate transporter (TPT) family, which is part of the drug/metabolite transporter (DMT) superfamily. It may function either as a GDP-fucose transporter that competes with Slc35c1 (S35C1) for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells.


Pssm-ID: 411044  Cd Length: 248  Bit Score: 196.34  E-value: 2.09e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 141 WRDYFVRVVPTALGTAMDINLSNESLVFISVTFATMCKSAAPIFLLLFAFAFRLESPSLKLFGIISVISAGVLLTVAKET 220
Cdd:cd21092    1 WSDYLKRVAPTGLASALDIGLSNWSFLFITVSLYTMTKSSAIIFILFFSLVFKLEKPRWSLVLVVLLIAGGLFMFTYKST 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 221 EFEFWGFVFVMLAAVMSGFRWCMTQVLLQKETFGLKNPFIFMSCVAPVMAIATGLLSLLLDPWSEFRDNKYF--DSGAHF 298
Cdd:cd21092   81 QFNLEGFILVLSASFLGGLRWTLAQLLMQKAELGLQNPIDMMYHLQPWMILGLLPLAIGFEGLHLATSEKLFrfHDSSVL 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 219783558 299 ARTCFLMLFGGALAFCMVLTEYVLVSVTSAVTVTIAGVVKEAVTIVVAVFYFHDEFTWLKGVGLMIIMVGVSL 371
Cdd:cd21092  161 LRTLGYLLLGAVLAFGLEFSEFLLVSKTSSLTLSIAGIFKEICTLLLAVHINGDHLSLLNWLGLVICLCGISL 233
TPT pfam03151
Triose-phosphate Transporter family; This family includes transporters with a specificity for ...
73-373 8.14e-25

Triose-phosphate Transporter family; This family includes transporters with a specificity for triose phosphate.


Pssm-ID: 308657 [Multi-domain]  Cd Length: 290  Bit Score: 103.14  E-value: 8.14e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558   73 LKTLFFILVWYTFSTFLTLYNKTLLGddlgKFPAPLLMNTIHFsiqAVLSKMITWYWSGRFQPDVTISWRdYFVRVVPTA 152
Cdd:pfam03151   1 LKLGLLFGLWYFLNIYFNIYNKKILN----AFPYPMTVSSVQL---FVGSVYILVLWGTGLRKRPKISSP-FLKNILPLA 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  153 LGTAMDINLSNESLVFISVTFATMCKSAAPIFLLLFAFAFRLESPSLKLFGIISVISAGVLLTVAKETEFEFWGFVFVML 232
Cdd:pfam03151  73 LCHTLGHVLANVSLGKVAVSFTHTVKAMEPFFTVILSRLFLGEYPPLLVYLSLLPIVGGVALASVTELSFNWIGFISAMI 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  233 AAVMSGFRWCMTQVLLQKeTFGLKNPFIFmscvapvmAIATGLLSLLLDPWSEFRDNKYFD------SGAHFARTCFLML 306
Cdd:pfam03151 153 SNLGFSLRNIFSKKLMKG-KDNLDNLNLF--------AIITILSLLLLLPVWLLVEGFKKFpsllqsGKVGLKDVYMLLL 223
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 219783558  307 FGGALAFCMVLTEYVLVSVTSAVTVTIAGVVKEAVTIVVAVFYFHDEFTWLKGVGLMIIMVGVSLFN 373
Cdd:pfam03151 224 LSGVCFHLYNQVAYMILERVSPVTHSVANTVKRVVVIVSSILVFGNPVSPLNAIGTAIAIAGVFLYS 290
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
107-374 9.33e-14

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 71.41  E-value: 9.33e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 107 PLLMNTIHFSIQAVLSKMITWYWSGRFQPDVTISWRDYFVRVVptaLGTAMDINLSNESLVFISVTFATMCKSAAPIFLL 186
Cdd:COG0697   31 PLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDWLLLLLRGL---LGLALAFLLFFLALQYTPAALAALLLALAPLFVA 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 187 LFAFAFRLESPSLKLFGIISVISAGVLLTVAKETEFEF---WGFVFVMLAAVMSGFRWCMTQVLLQKEtfglkNPFIFMS 263
Cdd:COG0697  108 LLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGGGgslLGDLLALLAALSWALYTVLTRRLSRRL-----DPLTLTF 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 264 CVAPVMAIATGLLSLLLDPWSEFrdnkyfdSGAHFARTCFLMLFGGALAFCMVlteYVLVSVTSAVTVTIAGVVKEAVTI 343
Cdd:COG0697  183 WQMLVGALLLLPLALLTGLPLPL-------SAAAWLALLYLGLFGTALAYLLW---FRALRRLGASRAAPLTYLEPVFAV 252
                        250       260       270
                 ....*....|....*....|....*....|.
gi 219783558 344 VVAVFYFHDEFTWLKGVGLMIIMVGVSLFNW 374
Cdd:COG0697  253 LLGWLLLGEPLTPLQLLGAALILAGVLLAAL 283
tpt TIGR00817
Tpt phosphate/phosphoenolpyruvate translocator; The 6-8 TMS Triose-phosphate Transporter (TPT) ...
73-372 1.35e-10

Tpt phosphate/phosphoenolpyruvate translocator; The 6-8 TMS Triose-phosphate Transporter (TPT) Family (TC 2.A.7.9)Functionally characterized members of the TPT family are derived from the inner envelope membranes of chloroplasts and nongreen plastids of plants. However,homologues are also present in yeast. Saccharomyces cerevisiae has three functionally uncharacterized TPT paralogues encoded within its genome. Under normal physiologicalconditions, chloroplast TPTs mediate a strict antiport of substrates, frequently exchanging an organic three carbon compound phosphate ester for inorganic phosphate (Pi).Normally, a triose-phosphate, 3-phosphoglycerate, or another phosphorylated C3 compound made in the chloroplast during photosynthesis, exits the organelle into thecytoplasm of the plant cell in exchange for Pi. However, experiments with reconstituted translocator in artificial membranes indicate that transport can also occur by achannel-like uniport mechanism with up to 10-fold higher transport rates. Channel opening may be induced by a membrane potential of large magnitude and/or by high substrateconcentrations. Nongreen plastid and chloroplast carriers, such as those from maize endosperm and root membranes, mediate transport of C3 compounds phosphorylated atcarbon atom 2, particularly phosphenolpyruvate, in exchange for Pi. These are the phosphoenolpyruvate:Pi antiporters (PPT). Glucose-6-P has also been shown to be asubstrate of some plastid translocators (GPT). The three types of proteins (TPT, PPT and GPT) are divergent in sequence as well as substrate specificity, but their substratespecificities overlap. [Hypothetical proteins, Conserved]


Pssm-ID: 129898 [Multi-domain]  Cd Length: 302  Bit Score: 62.05  E-value: 1.35e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558   73 LKTLFFILVWYTFSTFLTLYNKTLLGddlgKFPAPLLMNTIHFsiqAVLSKMITWYWSGRFQPDVTISWRDYFVrVVPTA 152
Cdd:TIGR00817   1 LQTGLLFGLWYFLNVYFNIYNKKLLN----VFPYPYFKTLISL---AVGSLYCLLSWSSGLPKRLKISSALLKL-LLPVA 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  153 LGTAMDINLSNESLVFISVTFATMCKSAAPIFLLLFAFAFRLESPSLKLFGIISVISAGVLLTVAKETEFEFWGFVFVML 232
Cdd:TIGR00817  73 IVHTIGHVTSNVSLSKVAVSFTHTIKAMEPFFSVVLSAFFLGQEFPSTLWLSLLPIVGGVALASDTELSFNWAGFLSAMI 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  233 AAVMSGFRWCMTQVLLQKETFGLKNPFIFMSCVAPVMAIATGLLSLLLDPWSEFRDNKYFDSGAHFARTCFLMLFGGALA 312
Cdd:TIGR00817 153 SNITFVSRNIFSKKAMTIKSLDKTNLYAYISIMSLFLLSPPAFITEGPPFLPHGFMQAISGVNVTKIYTVSLVAAMGFFH 232
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  313 FCMVLTeYVLVSVTSAVTVTIAGVVKEAVTIVVAVFYFHDEFTWLKGVGLMIIMVGVSLF 372
Cdd:TIGR00817 233 FYQQVA-FMLLGRVSPLTHSVGNCMKRVVVIVVSILFFGTKISPQQVFGTGIAIAGVFLY 291
PTZ00343 PTZ00343
triose or hexose phosphate/phosphate translocator; Provisional
62-376 3.18e-08

triose or hexose phosphate/phosphate translocator; Provisional


Pssm-ID: 240371 [Multi-domain]  Cd Length: 350  Bit Score: 55.13  E-value: 3.18e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  62 ASKVDISPADVLKTLFFILVWYTFSTFLTLYNKTLLGddlgKFPAPLLMNTIHFSIQAVLSKMitwYWSGRFQPDVTI-S 140
Cdd:PTZ00343  37 HSLFESFPNFKWKLALLFLTWYALNVLYVVDNKLALN----MLPLPWTISSLQLFVGWLFALL---YWATGFRKIPRIkS 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 141 WRDYFVRVVPTALGTAMDINLSNESLVFISVTFATMCKSAAPIFLLLFAFAFRLESPSLKLFGIISVISAGVLLTVAKET 220
Cdd:PTZ00343 110 LKLFLKNFLPQGLCHLFVHFGAVISMGLGAVSFTHVVKAAEPVFTALLSILFLKQFLNLYAYLSLIPIVGGVALASVKEL 189
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 221 EFEFWGFVFVMLAAVMSGFRWCMTQVLL-QKETFG--LKNPFIFMscvapVMAIATGLLSLLL------DPWSEFRDNKY 291
Cdd:PTZ00343 190 HFTWLAFWCAMLSNLGSSLRSIFAKKTMkNKSEIGenLTASNIYM-----LLTLIASLISLPLvlffegKKWVPVWTNYT 264
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 292 F-DSGAHFARTCFLMLFGGALAFCMVLTEYVLVSVTSAVTVTIAGVVKEAVTIVVAVFYFHDEFTWLKGVGLMIIMVGVS 370
Cdd:PTZ00343 265 AnMTNYTKGIIIFKIFFSGVWYYLYNEVAFYCLGKVNQVTHAVANTLKRVVIIVSSIIIFQTQVTLLGYLGMAVAILGAL 344

                 ....*.
gi 219783558 371 LFNWYK 376
Cdd:PTZ00343 345 LYSLFK 350
 
Name Accession Description Interval E-value
TPT_S35C2 cd21092
solute carrier family 35 member C2, member of the triose-phosphate transporter family; Solute ...
141-371 2.09e-60

solute carrier family 35 member C2, member of the triose-phosphate transporter family; Solute carrier family 35 member C2 (S35C2 or Slc35c2), also called ovarian cancer-overexpressed gene 1 protein (OVCOV1), is a member of the triose-phosphate transporter (TPT) family, which is part of the drug/metabolite transporter (DMT) superfamily. It may function either as a GDP-fucose transporter that competes with Slc35c1 (S35C1) for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells.


Pssm-ID: 411044  Cd Length: 248  Bit Score: 196.34  E-value: 2.09e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 141 WRDYFVRVVPTALGTAMDINLSNESLVFISVTFATMCKSAAPIFLLLFAFAFRLESPSLKLFGIISVISAGVLLTVAKET 220
Cdd:cd21092    1 WSDYLKRVAPTGLASALDIGLSNWSFLFITVSLYTMTKSSAIIFILFFSLVFKLEKPRWSLVLVVLLIAGGLFMFTYKST 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 221 EFEFWGFVFVMLAAVMSGFRWCMTQVLLQKETFGLKNPFIFMSCVAPVMAIATGLLSLLLDPWSEFRDNKYF--DSGAHF 298
Cdd:cd21092   81 QFNLEGFILVLSASFLGGLRWTLAQLLMQKAELGLQNPIDMMYHLQPWMILGLLPLAIGFEGLHLATSEKLFrfHDSSVL 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 219783558 299 ARTCFLMLFGGALAFCMVLTEYVLVSVTSAVTVTIAGVVKEAVTIVVAVFYFHDEFTWLKGVGLMIIMVGVSL 371
Cdd:cd21092  161 LRTLGYLLLGAVLAFGLEFSEFLLVSKTSSLTLSIAGIFKEICTLLLAVHINGDHLSLLNWLGLVICLCGISL 233
TPT pfam03151
Triose-phosphate Transporter family; This family includes transporters with a specificity for ...
73-373 8.14e-25

Triose-phosphate Transporter family; This family includes transporters with a specificity for triose phosphate.


Pssm-ID: 308657 [Multi-domain]  Cd Length: 290  Bit Score: 103.14  E-value: 8.14e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558   73 LKTLFFILVWYTFSTFLTLYNKTLLGddlgKFPAPLLMNTIHFsiqAVLSKMITWYWSGRFQPDVTISWRdYFVRVVPTA 152
Cdd:pfam03151   1 LKLGLLFGLWYFLNIYFNIYNKKILN----AFPYPMTVSSVQL---FVGSVYILVLWGTGLRKRPKISSP-FLKNILPLA 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  153 LGTAMDINLSNESLVFISVTFATMCKSAAPIFLLLFAFAFRLESPSLKLFGIISVISAGVLLTVAKETEFEFWGFVFVML 232
Cdd:pfam03151  73 LCHTLGHVLANVSLGKVAVSFTHTVKAMEPFFTVILSRLFLGEYPPLLVYLSLLPIVGGVALASVTELSFNWIGFISAMI 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  233 AAVMSGFRWCMTQVLLQKeTFGLKNPFIFmscvapvmAIATGLLSLLLDPWSEFRDNKYFD------SGAHFARTCFLML 306
Cdd:pfam03151 153 SNLGFSLRNIFSKKLMKG-KDNLDNLNLF--------AIITILSLLLLLPVWLLVEGFKKFpsllqsGKVGLKDVYMLLL 223
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 219783558  307 FGGALAFCMVLTEYVLVSVTSAVTVTIAGVVKEAVTIVVAVFYFHDEFTWLKGVGLMIIMVGVSLFN 373
Cdd:pfam03151 224 LSGVCFHLYNQVAYMILERVSPVTHSVANTVKRVVVIVSSILVFGNPVSPLNAIGTAIAIAGVFLYS 290
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
107-374 9.33e-14

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 71.41  E-value: 9.33e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 107 PLLMNTIHFSIQAVLSKMITWYWSGRFQPDVTISWRDYFVRVVptaLGTAMDINLSNESLVFISVTFATMCKSAAPIFLL 186
Cdd:COG0697   31 PLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDWLLLLLRGL---LGLALAFLLFFLALQYTPAALAALLLALAPLFVA 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 187 LFAFAFRLESPSLKLFGIISVISAGVLLTVAKETEFEF---WGFVFVMLAAVMSGFRWCMTQVLLQKEtfglkNPFIFMS 263
Cdd:COG0697  108 LLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGGGgslLGDLLALLAALSWALYTVLTRRLSRRL-----DPLTLTF 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 264 CVAPVMAIATGLLSLLLDPWSEFrdnkyfdSGAHFARTCFLMLFGGALAFCMVlteYVLVSVTSAVTVTIAGVVKEAVTI 343
Cdd:COG0697  183 WQMLVGALLLLPLALLTGLPLPL-------SAAAWLALLYLGLFGTALAYLLW---FRALRRLGASRAAPLTYLEPVFAV 252
                        250       260       270
                 ....*....|....*....|....*....|.
gi 219783558 344 VVAVFYFHDEFTWLKGVGLMIIMVGVSLFNW 374
Cdd:COG0697  253 LLGWLLLGEPLTPLQLLGAALILAGVLLAAL 283
tpt TIGR00817
Tpt phosphate/phosphoenolpyruvate translocator; The 6-8 TMS Triose-phosphate Transporter (TPT) ...
73-372 1.35e-10

Tpt phosphate/phosphoenolpyruvate translocator; The 6-8 TMS Triose-phosphate Transporter (TPT) Family (TC 2.A.7.9)Functionally characterized members of the TPT family are derived from the inner envelope membranes of chloroplasts and nongreen plastids of plants. However,homologues are also present in yeast. Saccharomyces cerevisiae has three functionally uncharacterized TPT paralogues encoded within its genome. Under normal physiologicalconditions, chloroplast TPTs mediate a strict antiport of substrates, frequently exchanging an organic three carbon compound phosphate ester for inorganic phosphate (Pi).Normally, a triose-phosphate, 3-phosphoglycerate, or another phosphorylated C3 compound made in the chloroplast during photosynthesis, exits the organelle into thecytoplasm of the plant cell in exchange for Pi. However, experiments with reconstituted translocator in artificial membranes indicate that transport can also occur by achannel-like uniport mechanism with up to 10-fold higher transport rates. Channel opening may be induced by a membrane potential of large magnitude and/or by high substrateconcentrations. Nongreen plastid and chloroplast carriers, such as those from maize endosperm and root membranes, mediate transport of C3 compounds phosphorylated atcarbon atom 2, particularly phosphenolpyruvate, in exchange for Pi. These are the phosphoenolpyruvate:Pi antiporters (PPT). Glucose-6-P has also been shown to be asubstrate of some plastid translocators (GPT). The three types of proteins (TPT, PPT and GPT) are divergent in sequence as well as substrate specificity, but their substratespecificities overlap. [Hypothetical proteins, Conserved]


Pssm-ID: 129898 [Multi-domain]  Cd Length: 302  Bit Score: 62.05  E-value: 1.35e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558   73 LKTLFFILVWYTFSTFLTLYNKTLLGddlgKFPAPLLMNTIHFsiqAVLSKMITWYWSGRFQPDVTISWRDYFVrVVPTA 152
Cdd:TIGR00817   1 LQTGLLFGLWYFLNVYFNIYNKKLLN----VFPYPYFKTLISL---AVGSLYCLLSWSSGLPKRLKISSALLKL-LLPVA 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  153 LGTAMDINLSNESLVFISVTFATMCKSAAPIFLLLFAFAFRLESPSLKLFGIISVISAGVLLTVAKETEFEFWGFVFVML 232
Cdd:TIGR00817  73 IVHTIGHVTSNVSLSKVAVSFTHTIKAMEPFFSVVLSAFFLGQEFPSTLWLSLLPIVGGVALASDTELSFNWAGFLSAMI 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  233 AAVMSGFRWCMTQVLLQKETFGLKNPFIFMSCVAPVMAIATGLLSLLLDPWSEFRDNKYFDSGAHFARTCFLMLFGGALA 312
Cdd:TIGR00817 153 SNITFVSRNIFSKKAMTIKSLDKTNLYAYISIMSLFLLSPPAFITEGPPFLPHGFMQAISGVNVTKIYTVSLVAAMGFFH 232
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  313 FCMVLTeYVLVSVTSAVTVTIAGVVKEAVTIVVAVFYFHDEFTWLKGVGLMIIMVGVSLF 372
Cdd:TIGR00817 233 FYQQVA-FMLLGRVSPLTHSVGNCMKRVVVIVVSILFFGTKISPQQVFGTGIAIAGVFLY 291
PTZ00343 PTZ00343
triose or hexose phosphate/phosphate translocator; Provisional
62-376 3.18e-08

triose or hexose phosphate/phosphate translocator; Provisional


Pssm-ID: 240371 [Multi-domain]  Cd Length: 350  Bit Score: 55.13  E-value: 3.18e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  62 ASKVDISPADVLKTLFFILVWYTFSTFLTLYNKTLLGddlgKFPAPLLMNTIHFSIQAVLSKMitwYWSGRFQPDVTI-S 140
Cdd:PTZ00343  37 HSLFESFPNFKWKLALLFLTWYALNVLYVVDNKLALN----MLPLPWTISSLQLFVGWLFALL---YWATGFRKIPRIkS 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 141 WRDYFVRVVPTALGTAMDINLSNESLVFISVTFATMCKSAAPIFLLLFAFAFRLESPSLKLFGIISVISAGVLLTVAKET 220
Cdd:PTZ00343 110 LKLFLKNFLPQGLCHLFVHFGAVISMGLGAVSFTHVVKAAEPVFTALLSILFLKQFLNLYAYLSLIPIVGGVALASVKEL 189
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 221 EFEFWGFVFVMLAAVMSGFRWCMTQVLL-QKETFG--LKNPFIFMscvapVMAIATGLLSLLL------DPWSEFRDNKY 291
Cdd:PTZ00343 190 HFTWLAFWCAMLSNLGSSLRSIFAKKTMkNKSEIGenLTASNIYM-----LLTLIASLISLPLvlffegKKWVPVWTNYT 264
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558 292 F-DSGAHFARTCFLMLFGGALAFCMVLTEYVLVSVTSAVTVTIAGVVKEAVTIVVAVFYFHDEFTWLKGVGLMIIMVGVS 370
Cdd:PTZ00343 265 AnMTNYTKGIIIFKIFFSGVWYYLYNEVAFYCLGKVNQVTHAVANTLKRVVIIVSSIIIFQTQVTLLGYLGMAVAILGAL 344

                 ....*.
gi 219783558 371 LFNWYK 376
Cdd:PTZ00343 345 LYSLFK 350
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
107-216 1.78e-04

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 41.41  E-value: 1.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  107 PLLMNTIHFSIQAVLSKMITWYWSGRFQpdvtISWRDYFVRVVPTALGTAMDINLSNESLVFISVTFATMCKSAAPIFLL 186
Cdd:pfam00892  30 PLTLTFWRFLIAGILLLPFALFTGGKLV----IPLKSWLALLYLGVLGTFLGFLLYFYGLKYVSASNASVITSLSPVFTL 105
                          90       100       110
                  ....*....|....*....|....*....|
gi 219783558  187 LFAFAFRLESPSLKLFGIISVISAGVLLTV 216
Cdd:pfam00892 106 ILSVLLLGEKLTLKQLLGIVLILLGVLLIL 135
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
133-373 6.03e-04

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 41.51  E-value: 6.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  133 FQPDVTISWRDYFVRVVPTALGTAmdinLSNESLVF-ISVTFATMCKSAAPIFLLLFAFAFRLESPSLKLFGIISVISAG 211
Cdd:pfam08449  59 FLKPRKIPLKTYVILVALFFITSV----LNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLG 134
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  212 VLL-TVAKETEFE----------FWGFVFVMLAAVMSGFrwcmtQVLLQKETFGLKNPfifmsCVAPVMAIATGL-LSLL 279
Cdd:pfam08449 135 IIIfTLFSAKDKVadsvvspnffLIGIAMLSGALLLDAF-----LGNYQEKTYKKYGK-----HSKEMLFYSHLLsLPFF 204
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  280 LDPWSEFRDNKYFDSgAHFARTCFLMLFGGALAFCMVLTEYV-------LVSVTSAVTVTIAGVVKEAVTIVVAVFYFHD 352
Cdd:pfam08449 205 LLLQGDLFSAVQFCS-QSPDKAVLSLPSMLFYLLLNVLTQYVcirgvfiLISEFGALTVTLVTTLRKFVSLLLSILLFGN 283
                         250       260
                  ....*....|....*....|.
gi 219783558  353 EFTWLKGVGLMIIMVGVSLFN 373
Cdd:pfam08449 284 PFTLQHWVGTLLVFLGTFLYS 304
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
225-374 1.38e-03

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 38.72  E-value: 1.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  225 WGFVFVMLAAVMSGFRWCMTQVLLQKEtfglknPFIFMSCVAPVMAiatgllSLLLDPWSEFRDNKYFDSGAHFARTCFL 304
Cdd:pfam00892   2 KGILLALLAALIWAIYFVFSKILLRRI------SPLTLTFWRFLIA------GILLLPFALFTGGKLVIPLKSWLALLYL 69
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  305 MLFGGALAFCMVLTEYVLVSVTSAVTVTIAGVVkeaVTIVVAVFYFHDEFTWLKGVGLMIIMVGVSLFNW 374
Cdd:pfam00892  70 GVLGTFLGFLLYFYGLKYVSASNASVITSLSPV---FTLILSVLLLGEKLTLKQLLGIVLILLGVLLILL 136
PUNUT pfam16913
Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal ...
166-370 2.23e-03

Purine nucleobase transmembrane transport; PUNUT is a family of largely plant and fungal purine transporters. Most members are 10-pass transmembrane proteins, and they belong to the drug/metabolite transporter (dmt) superfamily. The plant vascular system transports nucloebases and their derivatives such as cytokinins and caffeine by a common H+-coupled high-affinity purine transport system; the PUNUT family members carry out this transport.


Pssm-ID: 293518 [Multi-domain]  Cd Length: 321  Bit Score: 39.96  E-value: 2.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  166 LVFISVTFATMCKSAAPIFLLLFAFAFRlespSLKL--FGIISV----ISAGVLL-------TVAKETEFEFWGFVFVML 232
Cdd:pfam16913  95 LLYLPVSTFSLILATQLAFTAIFSYFIN----KQKFtpFIINSVvlltISAALLAldsssdkPSGESKKKYVIGFWCTIG 170
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219783558  233 AAVMSGFRWCMTQV----LLQKETFGLKNPF-IFMSCVAPVMAIATGLLSllldpwSEFRDNKYFDSGAHFARTCFLM-L 306
Cdd:pfam16913 171 ASALFSLILCLVELafekVLKRRTFSMVLEMqIVMSLVATCVCVIGLFAS------GEFKDLKGEMEEFKKGKSLYVLtL 244
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 219783558  307 FGGALAF-CMVLTEYVLVSVTSAVTVTIAGVVKEAVTIVVAVFYFHDEFTWLKGVGLMIIMVGVS 370
Cdd:pfam16913 245 VGTAVSWqVYFVGAVGLVFLVSSLFSNVISTVLLPVVPVLAVIAFHDKFSGFKGVALVLAIWGFA 309
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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