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Conserved domains on  [gi|2241884814|emb|CAH3960660|]
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hypothetical protein AI2666V1_5188 (plasmid) [Citrobacter freundii]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 20139204)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.1.-
Gene Ontology:  GO:0008080
PubMed:  9175471|10940244|15581578
SCOP:  3000403

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 89-154 1.08e-06

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


:

Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 44.65  E-value: 1.08e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2241884814  89 PSVTLGRLAIDKSIHHQGYGETLVTHAMkvvyQASQAVGIHGMFVEALNDN--AKKFYLRLGFIQLKE 154
Cdd:COG0456    12 DEAEIEDLAVDPEYRGRGIGRALLEAAL----ERARERGARRLRLEVREDNeaAIALYEKLGFEEVGE 75
PhnO super family cl42766
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 19-149 1.38e-05

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


The actual alignment was detected with superfamily member COG0454:

Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 42.73  E-value: 1.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241884814  19 NFDCGEEYLNTFLTDHLKRQHNskilRGYVLVTRENKPrvMGYYTLSgscfekillpsktqqkrvpYKNVPSVTLGRLAI 98
Cdd:COG0454    12 NFILLIEALDAELKAMEGSLAG----AEFIAVDDKGEP--IGFAGLR-------------------RLDDKVLELKRLYV 66

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2241884814  99 DKSIHHQGYGETLVTHAMKVvyqaSQAVGIHGMFVEALNDN--AKKFYLRLGF 149
Cdd:COG0454    67 LPEYRGKGIGKALLEALLEW----ARERGCTALELDTLDGNpaAIRFYERLGF 115
 
Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 89-154 1.08e-06

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 44.65  E-value: 1.08e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2241884814  89 PSVTLGRLAIDKSIHHQGYGETLVTHAMkvvyQASQAVGIHGMFVEALNDN--AKKFYLRLGFIQLKE 154
Cdd:COG0456    12 DEAEIEDLAVDPEYRGRGIGRALLEAAL----ERARERGARRLRLEVREDNeaAIALYEKLGFEEVGE 75
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 19-149 1.38e-05

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 42.73  E-value: 1.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241884814  19 NFDCGEEYLNTFLTDHLKRQHNskilRGYVLVTRENKPrvMGYYTLSgscfekillpsktqqkrvpYKNVPSVTLGRLAI 98
Cdd:COG0454    12 NFILLIEALDAELKAMEGSLAG----AEFIAVDDKGEP--IGFAGLR-------------------RLDDKVLELKRLYV 66

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2241884814  99 DKSIHHQGYGETLVTHAMKVvyqaSQAVGIHGMFVEALNDN--AKKFYLRLGF 149
Cdd:COG0454    67 LPEYRGKGIGKALLEALLEW----ARERGCTALELDTLDGNpaAIRFYERLGF 115
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 24-149 2.84e-05

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 41.35  E-value: 2.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241884814  24 EEYLNTFLTDHLKRQHNSKILRGYVLVTRENKPRVMGYYTLsgscfekillpsktqqkRVPYKNVPSVTLGRLAIDKSIH 103
Cdd:pfam00583  10 EEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASL-----------------SIIDDEPPVGEIEGLAVAPEYR 72

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2241884814 104 HQGYGETLVTHAMkvvyQASQAVGIHGMFVEALNDN--AKKFYLRLGF 149
Cdd:pfam00583  73 GKGIGTALLQALL----EWARERGCERIFLEVAADNlaAIALYEKLGF 116
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 83-151 4.37e-05

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 40.13  E-value: 4.37e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2241884814  83 VPYKNVPSVTLGRLAIDKSIHHQGYGETLVTHAMKvvyqASQAVGIHGMFVEALNdNAKKFYLRLGFIQ 151
Cdd:pfam13508  21 LPLDDEGALAELRLAVHPEYRGQGIGRALLEAAEA----AAKEGGIKLLELETTN-RAAAFYEKLGFEE 84
 
Name Accession Description Interval E-value
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 89-154 1.08e-06

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 44.65  E-value: 1.08e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2241884814  89 PSVTLGRLAIDKSIHHQGYGETLVTHAMkvvyQASQAVGIHGMFVEALNDN--AKKFYLRLGFIQLKE 154
Cdd:COG0456    12 DEAEIEDLAVDPEYRGRGIGRALLEAAL----ERARERGARRLRLEVREDNeaAIALYEKLGFEEVGE 75
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 93-155 6.52e-06

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 43.44  E-value: 6.52e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2241884814  93 LGRLAIDKSIHHQGYGETLVTHAMKvvyQASQAvGIHGMFVEAlNDNAKKFYLRLGFIQLKEE 155
Cdd:COG1246    55 LRSLAVHPDYRGRGIGRRLLEALLA---EAREL-GLKRLFLLT-TSAAIHFYEKLGFEEIDKE 112
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
85-156 1.10e-05

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 43.15  E-value: 1.10e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2241884814  85 YKNVPSVTLGRLAIDKSIHHQGYGETLVTHAMkvvyQASQAVGIHGMFVEAlNDNAKKFYLRLGFIQLKEEN 156
Cdd:COG3153    62 DGEGPALLLGPLAVDPEYRGQGIGRALMRAAL----EAARERGARAVVLLG-DPSLLPFYERFGFRPAGELG 128
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 19-149 1.38e-05

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 42.73  E-value: 1.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241884814  19 NFDCGEEYLNTFLTDHLKRQHNskilRGYVLVTRENKPrvMGYYTLSgscfekillpsktqqkrvpYKNVPSVTLGRLAI 98
Cdd:COG0454    12 NFILLIEALDAELKAMEGSLAG----AEFIAVDDKGEP--IGFAGLR-------------------RLDDKVLELKRLYV 66

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2241884814  99 DKSIHHQGYGETLVTHAMKVvyqaSQAVGIHGMFVEALNDN--AKKFYLRLGF 149
Cdd:COG0454    67 LPEYRGKGIGKALLEALLEW----ARERGCTALELDTLDGNpaAIRFYERLGF 115
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
82-155 1.59e-05

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 42.48  E-value: 1.59e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2241884814  82 RVPYKNVPSVTLGRLAIDKSIHHQGYGETLVTHAMKVVYQAsqavGIHGMFVEAlNDNAKKFYLRLGFIQLKEE 155
Cdd:COG2153    50 RLLPPGDGEAKIGRVAVLPEYRGQGLGRALMEAAIEEARER----GARRIVLSA-QAHAVGFYEKLGFVPVGEE 118
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 24-149 2.84e-05

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 41.35  E-value: 2.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241884814  24 EEYLNTFLTDHLKRQHNSKILRGYVLVTRENKPRVMGYYTLsgscfekillpsktqqkRVPYKNVPSVTLGRLAIDKSIH 103
Cdd:pfam00583  10 EEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASL-----------------SIIDDEPPVGEIEGLAVAPEYR 72

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2241884814 104 HQGYGETLVTHAMkvvyQASQAVGIHGMFVEALNDN--AKKFYLRLGF 149
Cdd:pfam00583  73 GKGIGTALLQALL----EWARERGCERIFLEVAADNlaAIALYEKLGF 116
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 83-151 4.37e-05

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 40.13  E-value: 4.37e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2241884814  83 VPYKNVPSVTLGRLAIDKSIHHQGYGETLVTHAMKvvyqASQAVGIHGMFVEALNdNAKKFYLRLGFIQ 151
Cdd:pfam13508  21 LPLDDEGALAELRLAVHPEYRGQGIGRALLEAAEA----AAKEGGIKLLELETTN-RAAAFYEKLGFEE 84
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
96-149 3.13e-04

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 39.21  E-value: 3.13e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2241884814  96 LAIDKSIHHQGYGETLVTHAMkvvyQASQAVGIHGMFVEALNDN--AKKFYLRLGF 149
Cdd:COG1247    86 IYVDPDARGRGIGRALLEALI----ERARARGYRRLVAVVLADNeaSIALYEKLGF 137
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 93-155 5.99e-04

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 38.02  E-value: 5.99e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2241884814  93 LGRLAIDKSIHHQGYGETLVTHAMKvvYQASQAVGIHGMFVEAlNDNAKKFYLRLGFIQLKEE 155
Cdd:pfam13673  54 ISLLFVDPDYQGQGIGKALLEAVED--YAEKDGIKLSELTVNA-SPYAVPFYEKLGFRATGPE 113
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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