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Conserved domains on  [gi|2241884806|emb|CAH3960182|]
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hypothetical protein AI2666V1_5180 (plasmid) [Citrobacter freundii]

Protein Classification

transposase( domain architecture ID 11459289)

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism; similar to Escherichia coli IS150 protein InsAB

CATH:  1.10.10.10
Gene Ontology:  GO:0006313|GO:0003677|GO:0004803
PubMed:  20885819

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
4-81 2.18e-23

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


:

Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 85.75  E-value: 2.18e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241884806   4 KRYPEEFKTEAVKQVVDRGYSVASVATRLDITTHSLYAWIKKY----GPDSSTNKEQSDAQAEIRRLQKELKRVTDERDI 79
Cdd:COG2963     6 RRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYreggLGGFPGDGRTTPEQAEIRRLRKELRRLEMENDI 85


                  ..
gi 2241884806  80 LK 81
Cdd:COG2963    86 LK 87
 
Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
4-81 2.18e-23

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 85.75  E-value: 2.18e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241884806   4 KRYPEEFKTEAVKQVVDRGYSVASVATRLDITTHSLYAWIKKY----GPDSSTNKEQSDAQAEIRRLQKELKRVTDERDI 79
Cdd:COG2963     6 RRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYreggLGGFPGDGRTTPEQAEIRRLRKELRRLEMENDI 85


                  ..
gi 2241884806  80 LK 81
Cdd:COG2963    86 LK 87
transpos_IS3 NF033516
IS3 family transposase;
9-81 2.61e-19

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 80.69  E-value: 2.61e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2241884806   9 EFKTEAVKQVVDRGYSVASVATRLDITTHSLYAWIKKY--GPDSSTNKEQ----SDAQAEIRRLQKELKRVTDERDILK 81
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYrgGGEAADAGRLkellTPEEEENRRLKRELAELRLENEILK 79
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 4-71 1.35e-14

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 62.76  E-value: 1.35e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2241884806   4 KRYPEEFKTEAVKQVVDRGYSVASVATRLDITTHSLYAWIKKYGPDSST---NKEQSDAQAEIRRLQKELK 71
Cdd:pfam01527   5 RRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEGGMGAspaRPRLTALEEENRRLKRELA 75
P PHA02535
terminase ATPase subunit; Provisional
 4-79 6.02e-03

terminase ATPase subunit; Provisional


Pssm-ID: 222859 [Multi-domain]  Cd Length: 581  Bit Score: 34.28  E-value: 6.02e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2241884806   4 KRYPEEFKTEAvKQVVDRGYSVASVATRLDITTHSLYAWIKKYGPDSSTNKEQSDAQAEIRRLQKELKRVTDERDI 79
Cdd:PHA02535    1 TAYDDDVRRAA-KFLYWQGWTVAEIAEELGLKSRTIYSWKERDGWRDLLPEERIEESIEARLIQLIEKENKTGGDY 75
 
Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
4-81 2.18e-23

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 85.75  E-value: 2.18e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241884806   4 KRYPEEFKTEAVKQVVDRGYSVASVATRLDITTHSLYAWIKKY----GPDSSTNKEQSDAQAEIRRLQKELKRVTDERDI 79
Cdd:COG2963     6 RRYSPEFKAEAVRLVLEGGASVAEVARELGISPSTLYRWVRQYreggLGGFPGDGRTTPEQAEIRRLRKELRRLEMENDI 85


                  ..
gi 2241884806  80 LK 81
Cdd:COG2963    86 LK 87
transpos_IS3 NF033516
IS3 family transposase;
9-81 2.61e-19

IS3 family transposase;


Pssm-ID: 468052 [Multi-domain]  Cd Length: 369  Bit Score: 80.69  E-value: 2.61e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2241884806   9 EFKTEAVKQVVDRGYSVASVATRLDITTHSLYAWIKKY--GPDSSTNKEQ----SDAQAEIRRLQKELKRVTDERDILK 81
Cdd:NF033516    1 EFKLEAVREVLEGGKSVAEVARELGISPSTLYRWRKKYrgGGEAADAGRLkellTPEEEENRRLKRELAELRLENEILK 79
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 4-71 1.35e-14

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 62.76  E-value: 1.35e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2241884806   4 KRYPEEFKTEAVKQVVDRGYSVASVATRLDITTHSLYAWIKKYGPDSST---NKEQSDAQAEIRRLQKELK 71
Cdd:pfam01527   5 RRFSEEFKLRAVKEVLEPGRTVKEVARRHGVSPNTLYQWRRQYEGGMGAspaRPRLTALEEENRRLKRELA 75
P PHA02535
terminase ATPase subunit; Provisional
 4-79 6.02e-03

terminase ATPase subunit; Provisional


Pssm-ID: 222859 [Multi-domain]  Cd Length: 581  Bit Score: 34.28  E-value: 6.02e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2241884806   4 KRYPEEFKTEAvKQVVDRGYSVASVATRLDITTHSLYAWIKKYGPDSSTNKEQSDAQAEIRRLQKELKRVTDERDI 79
Cdd:PHA02535    1 TAYDDDVRRAA-KFLYWQGWTVAEIAEELGLKSRTIYSWKERDGWRDLLPEERIEESIEARLIQLIEKENKTGGDY 75
DUF4461 pfam14688
Domain of unknown function (DUF4461); This domain family is found in eukaryotes, and is ...
 38-85 9.06e-03

Domain of unknown function (DUF4461); This domain family is found in eukaryotes, and is approximately 310 amino acids in length.


Pssm-ID: 464263  Cd Length: 304  Bit Score: 33.76  E-value: 9.06e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2241884806  38 SLYAWIKKYGPDSSTN-KEQSDAQAEIRRLQKELKRVTDERDILKNCPW 85
Cdd:pfam14688   1 TLSSWLRNNEKEARKKlKESLPLREEVKRLKGELCEQLGLKDIRWQCGW 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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