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Conserved domains on  [gi|53136534|emb|CAG32596|]
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hypothetical protein RCJMB04_30f20 [Gallus gallus]

Protein Classification

bromodomain-containing protein 8( domain architecture ID 10144714)

bromodomain-containing protein 8 (BRD8) may act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR)

CATH:  1.20.920.10
Gene Ontology:  GO:0030374|GO:0046966
PubMed:  31582847|28847823|34548613|1350857|26472704

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bromo_brd8_like cd05507
Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with ...
 782-885 1.60e-64

Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be a nuclear receptor coactivator. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


:

Pssm-ID: 99939  Cd Length: 104  Bit Score: 211.84  E-value: 1.60e-64
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 782 QKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNS 861
Cdd:cd05507   1 YRAWKKAILLVYRTLASHRYASVFLKPVTEDIAPGYHSVVYRPMDLSTIKKNIENGTIRSTAEFQRDVLLMFQNAIMYNS 80

                        90       100
                ....*....|....*....|....
gi 53136534 862 SDHDVYHMAVEMQRDVLEQIQQFL 885
Cdd:cd05507  81 SDHDVYLMAVEMQREVMSQIQQLL 104
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 203-413 8.62e-08

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.49  E-value: 8.62e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   203 LSQPAVDEASP-GVTPGTLPST--PVASFIGIPDTPPGSAPLDAPMTPVTDDSPQKKMLGQKATPPPSPLLSELLKKGSL 279
Cdd:PHA03247 2670 LGRAAQASSPPqRPRRRAARPTvgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA 2749

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   280 LPTSPRLVGEnemavasghmnssgvllevgsvlPVLHSGEMQSAPgavPASPAASGAPTLSRLLEAGPAQFTSPLASFSA 359
Cdd:PHA03247 2750 TPGGPARPAR-----------------------PPTTAGPPAPAP---PAAPAAGPPRRLTRPAVASLSESRESLPSPWD 2803

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 53136534   360 VASEPPAKLLPPPVEPVSQATIVMMPTLSAPSVVPPAAAPESVVTVSQPEACVS 413
Cdd:PHA03247 2804 PADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA 2857
 
Name Accession Description Interval E-value
Bromo_brd8_like cd05507
Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with ...
 782-885 1.60e-64

Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be a nuclear receptor coactivator. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99939  Cd Length: 104  Bit Score: 211.84  E-value: 1.60e-64
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 782 QKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNS 861
Cdd:cd05507   1 YRAWKKAILLVYRTLASHRYASVFLKPVTEDIAPGYHSVVYRPMDLSTIKKNIENGTIRSTAEFQRDVLLMFQNAIMYNS 80

                        90       100
                ....*....|....*....|....
gi 53136534 862 SDHDVYHMAVEMQRDVLEQIQQFL 885
Cdd:cd05507  81 SDHDVYLMAVEMQREVMSQIQQLL 104
BROMO smart00297
bromo domain;
782-884 2.60e-35

bromo domain;


Pssm-ID: 197636 [Multi-domain]  Cd Length: 107  Bit Score: 129.71  E-value: 2.60e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534    782 QKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNS 861
Cdd:smart00297   5 QKKLQELLKAVLDKLDSHPLSWPFLKPVSRKEAPDYYDIIKKPMDLKTIKKKLENGKYSSVEEFVADFNLMFSNARTYNG 84

                           90       100
                   ....*....|....*....|...
gi 53136534    862 SDHDVYHMAVEMQRDVLEQIQQF 884
Cdd:smart00297  85 PDSEVYKDAKKLEKFFEKKLREL 107
Bromodomain pfam00439
Bromodomain; Bromodomains are 110 amino acid long domains, that are found in many chromatin ...
 792-872 5.69e-24

Bromodomain; Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 425683 [Multi-domain]  Cd Length: 84  Bit Score: 96.61  E-value: 5.69e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   792 VWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAV 871
Cdd:pfam00439   4 ILDKLMEHPIAAPFLEPVDPDEYPDYYSVIKKPMDLSTIKKKLENGEYKSLAEFLADVKLIFSNARTYNGPGSVIYKAAE 83


                  .
gi 53136534   872 E 872
Cdd:pfam00439  84 K 84
COG5076 COG5076
Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin ...
 780-884 1.44e-15

Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription];


Pssm-ID: 227408 [Multi-domain]  Cd Length: 371  Bit Score: 79.46  E-value: 1.44e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 780 QAQKIWKKAIMLVWRAAANHryANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMY 859
Cdd:COG5076 146 DNKAIAKFKKQLFLRDGRFL--SSIFLGLPSKREYPDYYEIIKSPMDLLTIQKKLKNGRYKSFEEFVSDLNLMFDNCKLY 223

                        90       100
                ....*....|....*....|....*
gi 53136534 860 NSSDHDVYHMAVEMQRDVLEQIQQF 884
Cdd:COG5076 224 NGPDSSVYVDAKELEKYFLKLIEEI 248
PHA03247 PHA03247
large tegument protein UL36; Provisional
 203-413 8.62e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.49  E-value: 8.62e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   203 LSQPAVDEASP-GVTPGTLPST--PVASFIGIPDTPPGSAPLDAPMTPVTDDSPQKKMLGQKATPPPSPLLSELLKKGSL 279
Cdd:PHA03247 2670 LGRAAQASSPPqRPRRRAARPTvgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA 2749

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   280 LPTSPRLVGEnemavasghmnssgvllevgsvlPVLHSGEMQSAPgavPASPAASGAPTLSRLLEAGPAQFTSPLASFSA 359
Cdd:PHA03247 2750 TPGGPARPAR-----------------------PPTTAGPPAPAP---PAAPAAGPPRRLTRPAVASLSESRESLPSPWD 2803

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 53136534   360 VASEPPAKLLPPPVEPVSQATIVMMPTLSAPSVVPPAAAPESVVTVSQPEACVS 413
Cdd:PHA03247 2804 PADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA 2857
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 187-433 3.92e-04

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 44.18  E-value: 3.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   187 SPAGSTSPGGDYALGDLSQPAVDEASPGVTPGTLPSTPVASfigipdtppGSAPLDAPMTPVTDDSPQKKMLGQKATPPp 266
Cdd:pfam17823 124 SSAAQSLPAAIAALPSEAFSAPRAAACRANASAAPRAAIAA---------ASAPHAASPAPRTAASSTTAASSTTAASS- 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   267 SPLLSELLKKGSLLPTSPRLVGenemAVASGHMNSSGVLLEVGSVLPVlhSGEMQSAPGAV-PASPAASGAPTLSRLLEA 345
Cdd:pfam17823 194 APTTAASSAPATLTPARGISTA----ATATGHPAAGTALAAVGNSSPA--AGTVTAAVGTVtPAALATLAAAAGTVASAA 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   346 GPAQFTSPLASFSAVASEPPAKLLP----PPVEPVSQATIVMMPTLSAPSVVPPAAAPESVVTVSQPEACVSMEAVSDSH 421
Cdd:pfam17823 268 GTINMGDPHARRLSPAKHMPSDTMArnpaAPMGAQAQGPIIQVSTDQPVHNTAGEPTPSPSNTTLEPNTPKSVASTNLAV 347

                         250
                  ....*....|..
gi 53136534   422 TVTVSMDSSEIS 433
Cdd:pfam17823 348 VTTTKAQAKEPS 359
 
Name Accession Description Interval E-value
Bromo_brd8_like cd05507
Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with ...
 782-885 1.60e-64

Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be a nuclear receptor coactivator. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99939  Cd Length: 104  Bit Score: 211.84  E-value: 1.60e-64
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 782 QKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNS 861
Cdd:cd05507   1 YRAWKKAILLVYRTLASHRYASVFLKPVTEDIAPGYHSVVYRPMDLSTIKKNIENGTIRSTAEFQRDVLLMFQNAIMYNS 80

                        90       100
                ....*....|....*....|....
gi 53136534 862 SDHDVYHMAVEMQRDVLEQIQQFL 885
Cdd:cd05507  81 SDHDVYLMAVEMQREVMSQIQQLL 104
BROMO smart00297
bromo domain;
782-884 2.60e-35

bromo domain;


Pssm-ID: 197636 [Multi-domain]  Cd Length: 107  Bit Score: 129.71  E-value: 2.60e-35
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534    782 QKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNS 861
Cdd:smart00297   5 QKKLQELLKAVLDKLDSHPLSWPFLKPVSRKEAPDYYDIIKKPMDLKTIKKKLENGKYSSVEEFVADFNLMFSNARTYNG 84

                           90       100
                   ....*....|....*....|...
gi 53136534    862 SDHDVYHMAVEMQRDVLEQIQQF 884
Cdd:smart00297  85 PDSEVYKDAKKLEKFFEKKLREL 107
Bromodomain cd04369
Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear ...
 799-881 8.47e-29

Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.


Pssm-ID: 99922 [Multi-domain]  Cd Length: 99  Bit Score: 110.92  E-value: 8.47e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 799 HRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVL 878
Cdd:cd04369  17 RDLSEPFLEPVDPKEAPDYYEVIKNPMDLSTIKKKLKNGEYKSLEEFEADVRLIFSNAKTYNGPGSPIYKDAKKLEKLFE 96


                ...
gi 53136534 879 EQI 881
Cdd:cd04369  97 KLL 99
Bromodomain pfam00439
Bromodomain; Bromodomains are 110 amino acid long domains, that are found in many chromatin ...
 792-872 5.69e-24

Bromodomain; Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 425683 [Multi-domain]  Cd Length: 84  Bit Score: 96.61  E-value: 5.69e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   792 VWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAV 871
Cdd:pfam00439   4 ILDKLMEHPIAAPFLEPVDPDEYPDYYSVIKKPMDLSTIKKKLENGEYKSLAEFLADVKLIFSNARTYNGPGSVIYKAAE 83


                  .
gi 53136534   872 E 872
Cdd:pfam00439  84 K 84
Bromo_gcn5_like cd05509
Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates ...
 798-884 1.13e-21

Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99941 [Multi-domain]  Cd Length: 101  Bit Score: 90.31  E-value: 1.13e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 798 NHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDV 877
Cdd:cd05509  15 NHKSAWPFLEPVDKEEAPDYYDVIKKPMDLSTMEEKLENGYYVTLEEFVADLKLIFDNCRLYNGPDTEYYKCANKLEKFF 94


                ....*..
gi 53136534 878 LEQIQQF 884
Cdd:cd05509  95 WKKLKEL 101
Bromo_Brdt_II_like cd05498
Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET ...
 800-880 7.41e-20

Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99930  Cd Length: 102  Bit Score: 85.41  E-value: 7.41e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 800 RYANVFLQPVtDDIA---PGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQrD 876
Cdd:cd05498  19 AYAWPFYKPV-DPEAlglHDYHDIIKHPMDLSTIKKKLDNREYADAQEFAADVRLMFSNCYKYNPPDHPVHAMARKLQ-D 96


                ....
gi 53136534 877 VLEQ 880
Cdd:cd05498  97 VFED 100
Bromo_BDF1_2_II cd05499
Bromodomain. BDF1/BDF2 like subfamily, restricted to fungi, repeat II. BDF1 and BDF2 are yeast ...
 798-874 8.62e-20

Bromodomain. BDF1/BDF2 like subfamily, restricted to fungi, repeat II. BDF1 and BDF2 are yeast transcription factors involved in the expression of a wide range of genes, including snRNAs; they are required for sporulation and DNA repair and protect histone H4 from deacetylation. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99931  Cd Length: 102  Bit Score: 85.03  E-value: 8.62e-20
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 53136534 798 NHRYANVFLQPVTDDI--APGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQ 874
Cdd:cd05499  17 HSAYNWPFLDPVDPVAlnIPNYFSIIKKPMDLGTISKKLQNGQYQSAKEFERDVRLIFKNCYTFNPEGTDVYMMGHQLE 95
Bromo_plant1 cd05506
Bromodomain, uncharacterized subfamily specific to plants. Might function as a global ...
 799-873 1.70e-19

Bromodomain, uncharacterized subfamily specific to plants. Might function as a global transcription factor. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99938  Cd Length: 99  Bit Score: 84.30  E-value: 1.70e-19
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 53136534 799 HRYANVFLQPVtDDIA---PGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEM 873
Cdd:cd05506  15 HKWGWVFNAPV-DVVAlglPDYFDIIKKPMDLGTVKKKLEKGEYSSPEEFAADVRLTFANAMRYNPPGNDVHTMAKEL 91
Bromo_brd7_like cd05513
Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown ...
 805-870 6.20e-17

Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene involved in nasopharyngeal carcinoma. The protein interacts with acetylated histone H3 via its bromodomain. Bromodomains are 110 amino acid long domains that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99945  Cd Length: 98  Bit Score: 77.07  E-value: 6.20e-17
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 53136534 805 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDhDVYHMA 870
Cdd:cd05513  22 FAFPVTDFIAPGYSSIIKHPMDFSTMKEKIKNNDYQSIEEFKDDFKLMCENAMKYNKPD-TIYYKA 86
Bromo_Acf1_like cd05504
Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was ...
 799-882 8.63e-17

Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) and regulates ISWI-induced nucleosome remodeling. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99936  Cd Length: 115  Bit Score: 77.05  E-value: 8.63e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 799 HRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVL 878
Cdd:cd05504  27 HKDSWPFLRPVSKIEVPDYYDIIKKPMDLGTIKEKLNMGEYKLAEEFLSDIQLVFSNCFLYNPEHTSVYKAGTRLQRFFI 106


                ....
gi 53136534 879 EQIQ 882
Cdd:cd05504 107 KRCR 110
Bromo_Brdt_I_like cd05497
Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET ...
 780-883 2.40e-16

Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99929  Cd Length: 107  Bit Score: 75.54  E-value: 2.40e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 780 QAQKIWKKAIMLVWRaaanHRYANVFLQPVtDDIA---PGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNA 856
Cdd:cd05497   5 QLQYLLKVVLKALWK----HKFAWPFQQPV-DAVKlnlPDYHKIIKTPMDLGTIKKRLENNYYWSASECIQDFNTMFTNC 79

                        90       100
                ....*....|....*....|....*..
gi 53136534 857 VMYNSSDHDVYHMAVEMQRDVLEQIQQ 883
Cdd:cd05497  80 YIYNKPGDDVVLMAQTLEKLFLQKLAQ 106
COG5076 COG5076
Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin ...
 780-884 1.44e-15

Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription];


Pssm-ID: 227408 [Multi-domain]  Cd Length: 371  Bit Score: 79.46  E-value: 1.44e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 780 QAQKIWKKAIMLVWRAAANHryANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMY 859
Cdd:COG5076 146 DNKAIAKFKKQLFLRDGRFL--SSIFLGLPSKREYPDYYEIIKSPMDLLTIQKKLKNGRYKSFEEFVSDLNLMFDNCKLY 223

                        90       100
                ....*....|....*....|....*
gi 53136534 860 NSSDHDVYHMAVEMQRDVLEQIQQF 884
Cdd:COG5076 224 NGPDSSVYVDAKELEKYFLKLIEEI 248
Bromo_BDF1_2_I cd05500
Bromodomain. BDF1/BDF2 like subfamily, restricted to fungi, repeat I. BDF1 and BDF2 are yeast ...
 805-875 2.06e-15

Bromodomain. BDF1/BDF2 like subfamily, restricted to fungi, repeat I. BDF1 and BDF2 are yeast transcription factors involved in the expression of a wide range of genes, including snRNAs; they are required for sporulation and DNA repair and protect histone H4 from deacetylation. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99932  Cd Length: 103  Bit Score: 72.73  E-value: 2.06e-15
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 53136534 805 FLQPVtDDIA---PGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQR 875
Cdd:cd05500  25 FLVPV-DPVKlniPHYPTIIKKPMDLGTIERKLKSNVYTSVEEFTADFNLMVDNCLTFNGPEHPVSQMGKRLQA 97
Bromo_SPT7_like cd05510
Bromodomain; SPT7_like subfamily. SPT7 is a yeast protein that functions as a component of the ...
 800-882 3.71e-15

Bromodomain; SPT7_like subfamily. SPT7 is a yeast protein that functions as a component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA, and SLIK. SAGA is involved in the RNA polymerase II-dependent transcriptional regulation of about 10% of all yeast genes. The SPT7 bromodomain has been shown to weakly interact with acetylated histone H3, but not H4. The human representative of this subfamily is cat eye syndrome critical region protein 2 (CECR2). Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99942 [Multi-domain]  Cd Length: 112  Bit Score: 72.47  E-value: 3.71e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 800 RYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSS-DHDVYHMAVEMQRDVL 878
Cdd:cd05510  24 EHSTPFLTKVSKREAPDYYDIIKKPMDLGTMLKKLKNLQYKSKAEFVDDLNLIWKNCLLYNSDpSHPLRRHANFMKKKAE 103


                ....
gi 53136534 879 EQIQ 882
Cdd:cd05510 104 HLLK 107
Bromo_TFIID cd05511
Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, ...
 805-873 7.74e-15

Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to acetylated histone H4. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99943 [Multi-domain]  Cd Length: 112  Bit Score: 71.53  E-value: 7.74e-15
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 53136534 805 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEM 873
Cdd:cd05511  21 FHTPVNKKKVPDYYKIIKRPMDLQTIRKKISKHKYQSREEFLEDIELIVDNSVLYNGPDSVYTKKAKEM 89
Bromo_cbp_like cd05495
Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase ...
 787-870 1.70e-14

Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to phosphorylated CREB protein and augments the activity of phosphorylated CREB to activate transcription of cAMP-responsive genes. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99927  Cd Length: 108  Bit Score: 70.16  E-value: 1.70e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 787 KAIMLVWRAAAN-HRYANVFLQPVTDDI--APGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSD 863
Cdd:cd05495   6 QALMPTLEKLYKqDPESLPFRQPVDPKLlgIPDYFDIVKNPMDLSTIRRKLDTGQYQDPWQYVDDVWLMFDNAWLYNRKT 85


                ....*..
gi 53136534 864 HDVYHMA 870
Cdd:cd05495  86 SRVYKYC 92
Bromo_tif1_like cd05502
Bromodomain; tif1_like subfamily. Tif1 (transcription intermediary factor 1) is a member of ...
 805-885 6.30e-14

Bromodomain; tif1_like subfamily. Tif1 (transcription intermediary factor 1) is a member of the tripartite motif (TRIM) protein family, which is characterized by a particular domain architecture. It functions by recruiting coactivators and/or corepressors to modulate transcription. Vertebrate Tif1-gamma, also labeled E3 ubiquitin-protein ligase TRIM33, plays a role in the control of hematopoiesis. Its homologue in Xenopus laevis, Ectodermin, has been shown to function in germ-layer specification and control of cell growth during embryogenesis. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99934 [Multi-domain]  Cd Length: 109  Bit Score: 68.86  E-value: 6.30e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 805 FLQPVTDDIaPGYHSIVQRPMDLSTIKKNIENGLIR---TTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQI 881
Cdd:cd05502  25 FHEPVSPSV-PNYYKIIKTPMDLSLIRKKLQPKSPQhysSPEEFVADVRLMFKNCYKFNEEDSEVAQAGKELELFFEEQL 103


                ....
gi 53136534 882 QQFL 885
Cdd:cd05502 104 KEIL 107
Bromo_AAA cd05528
Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long ...
 790-885 9.17e-14

Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. The structure(2DKW) in this alignment is an uncharacterized protein predicted from analysis of cDNA clones from human fetal liver


Pssm-ID: 99957  Cd Length: 112  Bit Score: 68.54  E-value: 9.17e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 790 MLVWRAAANHRYaNVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYN----SSDHD 865
Cdd:cd05528  10 DVLKRLASDKRF-NAFTKPVDEEEVPDYYEIIKQPMDLQTILQKLDTHQYLTAKDFLKDIDLIVTNALEYNpdrdPADKL 88

                        90       100
                ....*....|....*....|
gi 53136534 866 VYHMAVEMQRDVLEQIQQFL 885
Cdd:cd05528  89 IRSRACELRDEVHAMIEAEL 108
Bromo_brd1_like cd05512
Bromodomain; brd1_like subfamily. BRD1 is a mammalian gene which encodes for a nuclear protein ...
 802-876 3.44e-13

Bromodomain; brd1_like subfamily. BRD1 is a mammalian gene which encodes for a nuclear protein assumed to be a transcriptional regulator. BRD1 has been implicated with brain development and susceptibility to schizophrenia and bipolar affective disorder. Bromodomains are 110 amino acid long domains that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99944  Cd Length: 98  Bit Score: 66.27  E-value: 3.44e-13
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 53136534 802 ANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMqRD 876
Cdd:cd05512  19 AEIFSEPVDLSEVPDYLDHIKQPMDFSTMRKKLESQRYRTLEDFEADFNLIINNCLAYNAKDTIFYRAAVRL-RD 92
Bromo_BAZ2A_B_like cd05503
Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B ...
 805-875 5.07e-13

Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting protein 5) and hWALp3. The proteins may play roles in transcriptional regulation. Human Tip5 is part of a complex termed NoRC (nucleolar remodeling complex), which induces nucleosome sliding and may play a role in the regulation of the rDNA locus. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99935  Cd Length: 97  Bit Score: 65.86  E-value: 5.07e-13
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 53136534 805 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQR 875
Cdd:cd05503  21 FLEPVNTKLVPGYRKIIKKPMDFSTIREKLESGQYKTLEEFAEDVRLVFDNCETFNEDDSEVGRAGHNMRK 91
Bromo_polybromo_V cd05515
Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which ...
 798-883 5.24e-13

Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. It was shown that polybromo bromodomains bind to histone H3 at specific acetyl-lysine positions. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine, but not all the bromodomains in polybromo may bind to acetyl-lysine.


Pssm-ID: 99946  Cd Length: 105  Bit Score: 65.79  E-value: 5.24e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 798 NHRYANVFLQ-PVTDDIaPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRD 876
Cdd:cd05515  20 GRRLSLIFMRlPSKSEY-PDYYDVIKKPIDMEKIRSKIEGNQYQSLDDMVSDFVLMFDNACKYNEPDSQIYKDALTLQKV 98


                ....*..
gi 53136534 877 VLEQIQQ 883
Cdd:cd05515  99 LLETKRE 105
Bromo_SNF2 cd05519
Bromodomain, SNF2-like subfamily, specific to fungi. SNF2 is a yeast protein involved in ...
 786-881 8.44e-13

Bromodomain, SNF2-like subfamily, specific to fungi. SNF2 is a yeast protein involved in transcriptional activation, it is the catalytic component of the SWI/SNF ATP-dependent chromatin remodeling complex. The protein is essential for the regulation of gene expression (both positive and negative) of a large number of genes. The SWI/SNF complex changes chromatin structure by altering DNA-histone contacts within the nucleosome, which results in a re-positioning of the nucleosome and facilitates or represses the binding of gene-specific transcription factors. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99950  Cd Length: 103  Bit Score: 65.44  E-value: 8.44e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 786 KKAIMLVWRAAANHR------YANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMY 859
Cdd:cd05519   2 KAAMLEIYDAVLNCEdetgrkLSELFLEKPSKKLYPDYYVIIKRPIALDQIKRRIEGRAYKSLEEFLEDFHLMFANARTY 81

                        90       100
                ....*....|....*....|..
gi 53136534 860 NSSDHDVYHMAVEMQRDVLEQI 881
Cdd:cd05519  82 NQEGSIVYEDAVEMEKAFKKKY 103
Bromo_SNF2L2 cd05516
Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI ...
 788-884 2.53e-12

Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone receptors to boost transcriptional activation. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99947  Cd Length: 107  Bit Score: 63.99  E-value: 2.53e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 788 AIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVY 867
Cdd:cd05516  11 DVVIKYKDSDGRQLAEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLEDLEKDVMLLCQNAQTFNLEGSLIY 90

                        90
                ....*....|....*..
gi 53136534 868 HMAVEMQRDVLEQIQQF 884
Cdd:cd05516  91 EDSIVLQSVFKSARQKI 107
Bromo_WDR9_II cd05496
Bromodomain; WDR9 repeat II_like subfamily. WDR9 is a human gene located in the Down Syndrome ...
 785-873 2.84e-11

Bromodomain; WDR9 repeat II_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional regulator involved in chromatin remodeling and play a role in embryonic development. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99928  Cd Length: 119  Bit Score: 61.32  E-value: 2.84e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 785 WKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDH 864
Cdd:cd05496   6 WKKQCKELVNLMWDCEDSEPFRQPVDLLKYPDYRDIIDTPMDLGTVKETLFGGNYDDPMEFAKDVRLIFSNSKSYTPNKR 85

                        90
                ....*....|
gi 53136534 865 D-VYHMAVEM 873
Cdd:cd05496  86 SrIYSMTLRL 95
Bromo_Rsc1_2_II cd05522
Bromodomain, repeat II in Rsc1/2_like subfamily, specific to fungi. Rsc1 and Rsc2 are ...
 815-876 1.83e-10

Bromodomain, repeat II in Rsc1/2_like subfamily, specific to fungi. Rsc1 and Rsc2 are components of the RSC complex (remodeling the structure of chromatin), are essential for transcriptional control, and have a specific domain architecture including two bromodomains. The RSC complex has also been linked to homologous recombination and nonhomologous end-joining repair of DNA double strand breaks. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99953 [Multi-domain]  Cd Length: 104  Bit Score: 58.79  E-value: 1.83e-10
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 53136534 815 PGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRD 876
Cdd:cd05522  38 PEYYQEISNPISLDDIKKKVKRRKYKSFDQFLNDLNLMFENAKLYNENDSQEYKDAVLLEKE 99
Bromo_RACK7 cd05508
Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) ...
 805-870 4.37e-10

Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular proliferation. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99940  Cd Length: 99  Bit Score: 57.39  E-value: 4.37e-10
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 53136534 805 FLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMA 870
Cdd:cd05508  23 FLKPVDLEQFPDYAQYVFKPMDLSTLEKNVRKKAYGSTDAFLADAKWILHNAIIYNGGDHKLTQAA 88
Bromo_polybromo_III cd05520
Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which ...
 802-875 1.42e-09

Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. It was shown that polybromo bromodomains bind to histone H3 at specific acetyl-lysine positions. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine, but not all the bromodomains in polybromo may bind to acetyl-lysine.


Pssm-ID: 99951  Cd Length: 103  Bit Score: 56.19  E-value: 1.42e-09
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 53136534 802 ANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQR 875
Cdd:cd05520  24 AEPFLKLPSKRKYPDYYQEIKNPISLQQIRTKLKNGEYETLEELEADLNLMFENAKRYNVPNSRIYKDAEKLQK 97
Bromo_polybromo_IV cd05518
Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which ...
 790-881 3.66e-09

Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. It was shown that polybromo bromodomains bind to histone H3 at specific acetyl-lysine positions. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine, but not all the bromodomains in polybromo may bind to acetyl-lysine.


Pssm-ID: 99949 [Multi-domain]  Cd Length: 103  Bit Score: 55.14  E-value: 3.66e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 790 MLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHM 869
Cdd:cd05518  12 VLEYREGSGRRLCDLFMEKPSKKDYPDYYKIILEPIDLKTIEHNIRNDKYATEEELMDDFKLMFRNARHYNEEGSQVYED 91

                        90
                ....*....|..
gi 53136534 870 AvemqrDVLEQI 881
Cdd:cd05518  92 A-----NILEKV 98
Bromo_WSTF_like cd05505
Bromodomain; Williams syndrome transcription factor-like subfamily (WSTF-like). The ...
 799-866 1.38e-08

Bromodomain; Williams syndrome transcription factor-like subfamily (WSTF-like). The Williams-Beuren syndrome deletion transcript 9 is a putative transcriptional regulator. WSTF was found to play a role in vitamin D-mediated transcription as part of two chromatin remodeling complexes, WINAC and WICH. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99937  Cd Length: 97  Bit Score: 53.31  E-value: 1.38e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 53136534 799 HRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDV 866
Cdd:cd05505  15 YRFSWPFREPVTADEAEDYKKVITNPMDLQTMQTKCSCGSYSSVQEFLDDMKLVFSNAEKYYENGSYV 82
PHA03247 PHA03247
large tegument protein UL36; Provisional
 203-413 8.62e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.49  E-value: 8.62e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   203 LSQPAVDEASP-GVTPGTLPST--PVASFIGIPDTPPGSAPLDAPMTPVTDDSPQKKMLGQKATPPPSPLLSELLKKGSL 279
Cdd:PHA03247 2670 LGRAAQASSPPqRPRRRAARPTvgSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA 2749

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   280 LPTSPRLVGEnemavasghmnssgvllevgsvlPVLHSGEMQSAPgavPASPAASGAPTLSRLLEAGPAQFTSPLASFSA 359
Cdd:PHA03247 2750 TPGGPARPAR-----------------------PPTTAGPPAPAP---PAAPAAGPPRRLTRPAVASLSESRESLPSPWD 2803

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 53136534   360 VASEPPAKLLPPPVEPVSQATIVMMPTLSAPSVVPPAAAPESVVTVSQPEACVS 413
Cdd:PHA03247 2804 PADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA 2857
PHA03247 PHA03247
large tegument protein UL36; Provisional
 162-410 7.68e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 7.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   162 ATDAAYQARQAikNPPRRLTGVMVRSPAGSTSPGGDYALGDLSQPAVDEAS------PGVTPGTLPSTPVASF-IGIPDT 234
Cdd:PHA03247 2721 LPPGPAAARQA--SPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPappaapAAGPPRRLTRPAVASLsESRESL 2798

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   235 PPGSAPLDAPmTPVTDDSPQKKMLGQKATPPPSPLlsellkkgSLLPTSPrlvgenemAVASGHMNSSgvLLEVGSVLPv 314
Cdd:PHA03247 2799 PSPWDPADPP-AAVLAPAAALPPAASPAGPLPPPT--------SAQPTAP--------PPPPGPPPPS--LPLGGSVAP- 2858

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   315 lhSGEM--QSAPGAVPASPAASGAPTLSRLLEAGPAQFTSPLASFSAVASEPPAKLLPPPVEPVSQATIVMMPTLSAPS- 391
Cdd:PHA03247 2859 --GGDVrrRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPp 2936

                         250
                  ....*....|....*....
gi 53136534   392 VVPPAAAPESVVTVSQPEA 410
Cdd:PHA03247 2937 PRPQPPLAPTTDPAGAGEP 2955
Bromo_Rsc1_2_I cd05521
Bromodomain, repeat I in Rsc1/2_like subfamily, specific to fungi. Rsc1 and Rsc2 are ...
 815-881 9.88e-07

Bromodomain, repeat I in Rsc1/2_like subfamily, specific to fungi. Rsc1 and Rsc2 are components of the RSC complex (remodeling the structure of chromatin), are essential for transcriptional control, and have a specific domain architecture including two bromodomains. The RSC complex has also been linked to homologous recombination and nonhomologous end-joining repair of DNA double strand breaks. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99952  Cd Length: 106  Bit Score: 48.09  E-value: 9.88e-07
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 53136534 815 PGYHSIVQRPMDLSTIKKNIENglIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQI 881
Cdd:cd05521  38 PDYYKIIKNPLSLNTVKKRLPH--YTNAQEFVNDLAQIPWNARLYNTKGSVIYKYALILEKYINDVI 102
Bromo_polybromo_II cd05517
Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which ...
 812-875 4.66e-06

Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. It was shown that polybromo bromodomains bind to histone H3 at specific acetyl-lysine positions. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine, but not all the bromodomains in polybromo may bind to acetyl-lysine.


Pssm-ID: 99948  Cd Length: 103  Bit Score: 46.28  E-value: 4.66e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 53136534 812 DIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQR 875
Cdd:cd05517  34 VLYPDYYAVIKEPIDLKTIAQRIQSGYYKSIEDMEKDLDLMVKNAKTFNEPGSQVYKDANAIKK 97
Bromo_ASH1 cd05525
Bromodomain; ASH1_like sub-family. ASH1 (absent, small, or homeotic 1) is a member of the ...
 815-866 6.53e-06

Bromodomain; ASH1_like sub-family. ASH1 (absent, small, or homeotic 1) is a member of the trithorax-group in Drosophila melanogaster, an epigenetic transcriptional regulator of HOX genes. Drosophila ASH1 has been shown to methylate specific lysines in histones H3 and H4. Mammalian ASH1 has been shown to methylate histone H3. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99955 [Multi-domain]  Cd Length: 106  Bit Score: 45.84  E-value: 6.53e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 53136534 815 PGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDV 866
Cdd:cd05525  39 PDYYERITDPVDLSTIEKQILTGYYKTPEAFDSDMLKVFRNAEKYYGRKSPI 90
Bromo_polybromo_I cd05524
Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which ...
 815-885 2.46e-05

Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. It was shown that polybromo bromodomains bind to histone H3 at specific acetyl-lysine positions. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine, but not all the bromodomains in polybromo may bind to acetyl-lysine.


Pssm-ID: 99954 [Multi-domain]  Cd Length: 113  Bit Score: 44.25  E-value: 2.46e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 53136534 815 PGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFL 885
Cdd:cd05524  39 PEYYEVVSNPIDLLKIQQKLKTEEYDDVDDLTADFELLINNAKAYYKPDSPEHKDACKLWELFLSARNEVL 109
Bromo_polybromo_VI cd05526
Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which ...
 815-875 2.95e-05

Bromodomain, polybromo repeat VI. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. It was shown that polybromo bromodomains bind to histone H3 at specific acetyl-lysine positions. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine, but not all the bromodomains in polybromo may bind to acetyl-lysine.


Pssm-ID: 99956  Cd Length: 110  Bit Score: 43.89  E-value: 2.95e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 53136534 815 PGYHSI----VQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQR 875
Cdd:cd05526  34 PELAVDgvgpKKIPLTLDIIKRNVDKGRYRRLDKFQEDMFEVLERARRLSRTDSEIYEDAVELQQ 98
Bromo_WDR9_I_like cd05529
Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome ...
 805-885 8.03e-05

Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional regulator involved in chromatin remodeling and play a role in embryonic development. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99958  Cd Length: 128  Bit Score: 43.09  E-value: 8.03e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 805 FLQPVtdDIA---PGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVyhmaVEMQRDVLEQI 881
Cdd:cd05529  48 FEYPV--DLRawyPDYWNRVPVPMDLETIRSRLENRYYRSLEALRHDVRLILSNAETFNEPNSEI----AKKAKRLSDWL 121


                ....
gi 53136534 882 QQFL 885
Cdd:cd05529 122 LRIL 125
Bromo_ZMYND11 cd05492
Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear ...
 814-883 1.07e-04

Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene expression. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99924  Cd Length: 109  Bit Score: 42.37  E-value: 1.07e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 814 APGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQ 883
Cdd:cd05492  36 LPKRRRLIHTHLDVADIQEKINSEKYTSLEEFKADALLLLHNTAIFHGADSEQYDAARWLYRDTCHDLRE 105
PLN02217 PLN02217
probable pectinesterase/pectinesterase inhibitor
 318-418 1.07e-04

probable pectinesterase/pectinesterase inhibitor


Pssm-ID: 215130 [Multi-domain]  Cd Length: 670  Bit Score: 46.24  E-value: 1.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534  318 GEMQSAPGAVPASPAASGAPTLSRLLEAGPAQF----TSPLASFSAVASEPPAKLLPPPVEPV-----SQATIVMMPTLS 388
Cdd:PLN02217 560 GLFAGNPGSTNSTPTGSAASSNTTFSSDSPSTVvapsTSPPAGHLGSPPATPSKIVSPSTSPPashlgSPSTTPSSPESS 639

                         90       100       110
                 ....*....|....*....|....*....|
gi 53136534  389 APSVVPPAAAPESVVTVSQPEACVSMEAVS 418
Cdd:PLN02217 640 IKVASTETASPESSIKVASTESSVSMVSMS 669
PHA03247 PHA03247
large tegument protein UL36; Provisional
 176-418 1.14e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 1.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   176 PPRRLTGVMVRSPAGSTSPGGDYAL--GDLSQPAVDEASPGVTPGTLPSTP-VASFIGIPDTPPGSApldAPMTPVTDDS 252
Cdd:PHA03247 2530 HPRMLTWIRGLEELASDDAGDPPPPlpPAAPPAAPDRSVPPPRPAPRPSEPaVTSRARRPDAPPQSA---RPRAPVDDRG 2606

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   253 PQKKMLGQKATPP-----------PSPLLSELlKKGSLLPTSPRLVGENEMAV--ASGHMNSSGVLLEVGSVLPvLHSGE 319
Cdd:PHA03247 2607 DPRGPAPPSPLPPdthapdppppsPSPAANEP-DPHPPPTVPPPERPRDDPAPgrVSRPRRARRLGRAAQASSP-PQRPR 2684

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   320 MQSAPGAVPASPAASGAPTLSRLLEAGPAQFTS----PLASFSAVASEP--PAKLLPP-----PVEPVSQATIVMMPTLS 388
Cdd:PHA03247 2685 RRAARPTVGSLTSLADPPPPPPTPEPAPHALVSatplPPGPAAARQASPalPAAPAPPavpagPATPGGPARPARPPTTA 2764

                         250       260       270
                  ....*....|....*....|....*....|
gi 53136534   389 APSVVPPAAAPESVVTVSQPEACVSMEAVS 418
Cdd:PHA03247 2765 GPPAPAPPAAPAAGPPRRLTRPAVASLSES 2794
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 187-433 3.92e-04

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 44.18  E-value: 3.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   187 SPAGSTSPGGDYALGDLSQPAVDEASPGVTPGTLPSTPVASfigipdtppGSAPLDAPMTPVTDDSPQKKMLGQKATPPp 266
Cdd:pfam17823 124 SSAAQSLPAAIAALPSEAFSAPRAAACRANASAAPRAAIAA---------ASAPHAASPAPRTAASSTTAASSTTAASS- 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   267 SPLLSELLKKGSLLPTSPRLVGenemAVASGHMNSSGVLLEVGSVLPVlhSGEMQSAPGAV-PASPAASGAPTLSRLLEA 345
Cdd:pfam17823 194 APTTAASSAPATLTPARGISTA----ATATGHPAAGTALAAVGNSSPA--AGTVTAAVGTVtPAALATLAAAAGTVASAA 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534   346 GPAQFTSPLASFSAVASEPPAKLLP----PPVEPVSQATIVMMPTLSAPSVVPPAAAPESVVTVSQPEACVSMEAVSDSH 421
Cdd:pfam17823 268 GTINMGDPHARRLSPAKHMPSDTMArnpaAPMGAQAQGPIIQVSTDQPVHNTAGEPTPSPSNTTLEPNTPKSVASTNLAV 347

                         250
                  ....*....|..
gi 53136534   422 TVTVSMDSSEIS 433
Cdd:pfam17823 348 VTTTKAQAKEPS 359
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
237-409 6.99e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.33  E-value: 6.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534  237 GSAPLDAPMTPVTDDSPQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRlvgenemAVASGHMNSSGVLLEVGSVLPVLH 316
Cdd:PRK12323 371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAV-------AAAPARRSPAPEALAAARQASARG 443

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534  317 SGEMQSAPGAVPASPAASGAPTLSRLLEAGPAQFTSPlASFSAVASEPPAKLLPPPVEPvsqativMMPTLSAPSVVPPA 396
Cdd:PRK12323 444 PGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAP-ARAAPAAAPAPADDDPPPWEE-------LPPEFASPAPAQPD 515

                        170
                 ....*....|...
gi 53136534  397 AAPESVVTVSQPE 409
Cdd:PRK12323 516 AAPAGWVAESIPD 528
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 324-410 9.06e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.16  E-value: 9.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534  324 PGAVPASPAASGAPTLSRLLEAGPAQFTSPLASFSAVASEPPAKLLPPPVEPVSQAtivMMPTLSAPSVVPPAAAPESVV 403
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAA---PPAPVAAPAAAAPAAAPAAAP 442


                 ....*..
gi 53136534  404 TVSQPEA 410
Cdd:PRK14951 443 AAVALAP 449
COG5076 COG5076
Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin ...
 798-867 2.29e-03

Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription];


Pssm-ID: 227408 [Multi-domain]  Cd Length: 371  Bit Score: 41.33  E-value: 2.29e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534 798 NHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVY 867
Cdd:COG5076 277 AHVGAWPFLRPVSDEEVPDYYKDIRDPMDLSTKELKLRNNYYRPEETFVRDAKLFFDNCVMYNGEVTDYY 346
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
322-407 6.47e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.22  E-value: 6.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534  322 SAPGAVPASPAASGAPTLSRLLEAGPAQFTSPLASFSAVASEPPAKLLPPPVEPVSQATIVMMPTLSAPSVVPPAAAPES 401
Cdd:PRK07003 417 AAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRA 496


                 ....*.
gi 53136534  402 VVTVSQ 407
Cdd:PRK07003 497 AAPSAA 502
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
181-410 7.48e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.22  E-value: 7.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534  181 TGVMVRSPAGSTSPGGDYALGDLSQPAVDEASPGvtPGTLPSTPVASFIGIPDTPPGSAPLDAPmtpvtddSPQKKMLGQ 260
Cdd:PRK07003 349 TMTLLRMLAFEPAVTGGGAPGGGVPARVAGAVPA--PGARAAAAVGASAVPAVTAVTGAAGAAL-------APKAAAAAA 419

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534  261 KATPPPSPLLSEllkkgsllPTSPRLVGENEMAVASghmnssgvllevgsvlPVLHSGEMQSAPGAVPASPAAsgAPTLS 340
Cdd:PRK07003 420 ATRAEAPPAAPA--------PPATADRGDDAADGDA----------------PVPAKANARASADSRCDERDA--QPPAD 473

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 53136534  341 RLLEAGPAQFTSPLASFsavASEPPAKLLPPPVEPVSQATIVMmPTLSAPSVVPPAAAPESVVTVSQPEA 410
Cdd:PRK07003 474 SGSASAPASDAPPDAAF---EPAPRAAAPSAATPAAVPDARAP-AAASREDAPAAAAPPAPEARPPTPAA 539
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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