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Conserved domains on  [gi|49609376|emb|CAF25041|]
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voltage-gated sodium channel Nav1.8c, partial [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Na_trans_assoc pfam06512
Sodium ion transport-associated; Members of this family contain a region found exclusively in ...
 12-134 5.33e-21

Sodium ion transport-associated; Members of this family contain a region found exclusively in eukaryotic sodium channels or their subunits, many of which are voltage-gated. Members very often also contain between one and four copies of pfam00520 and, less often, one copy of pfam00612.


:

Pssm-ID: 461936  Cd Length: 195  Bit Score: 83.54  E-value: 5.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 49609376    12 TKPALSSPKENHGDFITDPNVWVSVPIAEGESDLDELEEDmEQASQSSWQEedpkgqeqlpqvqkcenhqaarspasmms 91
Cdd:pfam06512  67 APGGKYELDEDHMDFITNPNLTVCVPIAEGESDLENEEDD-DESSQSSDEE----------------------------- 116

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 49609376    92 sedlapylgeswkrkDSPQVPAEGVDDTSSSEGSTVDCPDPEE 134
Cdd:pfam06512 117 ---------------KSKQQEQLEDDDSSSSEGSTVDLQDPEE 144
 
Name Accession Description Interval E-value
Na_trans_assoc pfam06512
Sodium ion transport-associated; Members of this family contain a region found exclusively in ...
 12-134 5.33e-21

Sodium ion transport-associated; Members of this family contain a region found exclusively in eukaryotic sodium channels or their subunits, many of which are voltage-gated. Members very often also contain between one and four copies of pfam00520 and, less often, one copy of pfam00612.


Pssm-ID: 461936  Cd Length: 195  Bit Score: 83.54  E-value: 5.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 49609376    12 TKPALSSPKENHGDFITDPNVWVSVPIAEGESDLDELEEDmEQASQSSWQEedpkgqeqlpqvqkcenhqaarspasmms 91
Cdd:pfam06512  67 APGGKYELDEDHMDFITNPNLTVCVPIAEGESDLENEEDD-DESSQSSDEE----------------------------- 116

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 49609376    92 sedlapylgeswkrkDSPQVPAEGVDDTSSSEGSTVDCPDPEE 134
Cdd:pfam06512 117 ---------------KSKQQEQLEDDDSSSSEGSTVDLQDPEE 144
 
Name Accession Description Interval E-value
Na_trans_assoc pfam06512
Sodium ion transport-associated; Members of this family contain a region found exclusively in ...
 12-134 5.33e-21

Sodium ion transport-associated; Members of this family contain a region found exclusively in eukaryotic sodium channels or their subunits, many of which are voltage-gated. Members very often also contain between one and four copies of pfam00520 and, less often, one copy of pfam00612.


Pssm-ID: 461936  Cd Length: 195  Bit Score: 83.54  E-value: 5.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 49609376    12 TKPALSSPKENHGDFITDPNVWVSVPIAEGESDLDELEEDmEQASQSSWQEedpkgqeqlpqvqkcenhqaarspasmms 91
Cdd:pfam06512  67 APGGKYELDEDHMDFITNPNLTVCVPIAEGESDLENEEDD-DESSQSSDEE----------------------------- 116

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 49609376    92 sedlapylgeswkrkDSPQVPAEGVDDTSSSEGSTVDCPDPEE 134
Cdd:pfam06512 117 ---------------KSKQQEQLEDDDSSSSEGSTVDLQDPEE 144
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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