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Conserved domains on  [gi|47169584|tpe|CAE51901|]
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TPA: stefin A3-like 1 precursor [Rattus norvegicus]

Protein Classification

CY domain-containing protein( domain architecture ID 10440427)

CY domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 43-106 1.68e-14

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


:

Pssm-ID: 425431  Cd Length: 92  Bit Score: 63.51  E-value: 1.68e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 47169584    43 VKPLLEEKT-NEKYEKFQAVDYKVQVVAGKNYFIKMDVG------HIKVFQGLSGED--DLELSGYHTNKTKN 106
Cdd:pfam00031  20 ALAEYNAKTdNYYFELVEVKRAKSQVVAGTNYFIKVEVGetdcskSKKLLEDCPLLDekWLGLCSAQVYKVPW 92
 
Name Accession Description Interval E-value
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 43-106 1.68e-14

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 63.51  E-value: 1.68e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 47169584    43 VKPLLEEKT-NEKYEKFQAVDYKVQVVAGKNYFIKMDVG------HIKVFQGLSGED--DLELSGYHTNKTKN 106
Cdd:pfam00031  20 ALAEYNAKTdNYYFELVEVKRAKSQVVAGTNYFIKVEVGetdcskSKKLLEDCPLLDekWLGLCSAQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 43-100 8.28e-09

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 48.96  E-value: 8.28e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 47169584     43 VKPLLEEKTNEKYE--KFQAVDYKVQVVAGKNYFIKMDVGHIKVFQGLSGEDDLELSGYH 100
Cdd:smart00043  23 AVAEYNKKSNDKYElrVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVDLENCPFLDQG 82
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 43-80 8.24e-06

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 41.31  E-value: 8.24e-06
                        10        20        30
                ....*....|....*....|....*....|....*....
gi 47169584  43 VKPLLEEKTNEKY-EKFQAVDYKVQVVAGKNYFIKMDVG 80
Cdd:cd00042  20 AVAEYNKKSNDKYlEFFKVLSAKSQVVAGTNYYITVEAG 58
 
Name Accession Description Interval E-value
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 43-106 1.68e-14

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 63.51  E-value: 1.68e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 47169584    43 VKPLLEEKT-NEKYEKFQAVDYKVQVVAGKNYFIKMDVG------HIKVFQGLSGED--DLELSGYHTNKTKN 106
Cdd:pfam00031  20 ALAEYNAKTdNYYFELVEVKRAKSQVVAGTNYFIKVEVGetdcskSKKLLEDCPLLDekWLGLCSAQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 43-100 8.28e-09

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 48.96  E-value: 8.28e-09
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 47169584     43 VKPLLEEKTNEKYE--KFQAVDYKVQVVAGKNYFIKMDVGHIKVFQGLSGEDDLELSGYH 100
Cdd:smart00043  23 AVAEYNKKSNDKYElrVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVDLENCPFLDQG 82
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 43-80 8.24e-06

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 41.31  E-value: 8.24e-06
                        10        20        30
                ....*....|....*....|....*....|....*....
gi 47169584  43 VKPLLEEKTNEKY-EKFQAVDYKVQVVAGKNYFIKMDVG 80
Cdd:cd00042  20 AVAEYNKKSNDKYlEFFKVLSAKSQVVAGTNYYITVEAG 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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