NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|6562168|emb|CAB62528|]
View 

hypothetical protein [Homo sapiens]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Glyco_transf_41 pfam13844
Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked ...
 95-635 0e+00

Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1.


:

Pssm-ID: 404688  Cd Length: 543  Bit Score: 1168.33  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168     95 VCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGR 174
Cdd:pfam13844   1 VCDWTDYESRMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHDFRKAIAARHANLCLEKIQILHKPPYKFPKDLSLSGGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    175 LRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHI 254
Cdd:pfam13844  81 LRIGYVSSDFGNHPTSHLMQSIPGFHDREKVEVFCYALSPDDGTNFRSKIARESEHFVDLSQIPCNGKAADRIHADGIHI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    255 LVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHL 334
Cdd:pfam13844 161 LVNMNGYTKGARNEIFALRPAPIQVMWLGYPGTSGASFMDYIITDAVTSPLELADQYSEKLAYMPHTFFIGDHRQMFPHL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    335 KKKAVIDFKSNG-HIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPD--GGDNADSSNTALNMPVIPMNTiAEAVIEMINR 411
Cdd:pfam13844 241 KERAIVTDKSDGtKVRDNVAVVNATDLKPLLEKTEVKDKVKEVVVVetTGNSRDSSKVEVVLPVIELPT-TEPIESMIQS 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    412 GQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSV 491
Cdd:pfam13844 320 GQIQTSVNGVVVQNGLATTQTNNKAATGEEVPSSIVVTTRQQYGLPDDAIVYCNFNQLYKIDPPTLEMWVNILKRVPNSV 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    492 LWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLA 571
Cdd:pfam13844 400 LWLLRFPAVGEPNILATAQELGIPPGRIVFSNVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTLPGETLA 479

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6562168    572 SRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMEL 635
Cdd:pfam13844 480 SRVAASQLATLGCPELIAKSRQEYEDIAVKLGTDREYLKAIRAKVWKARTTSPLFNVKQYTQDL 543
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
2-93 8.70e-26

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 106.63  E-value: 8.70e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:COG0457  30 DYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDD 109

                        90
                ....*....|..
gi 6562168   82 PDAYCNLAHCLQ 93
Cdd:COG0457 110 AEALYNLGLALL 121
 
Name Accession Description Interval E-value
Glyco_transf_41 pfam13844
Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked ...
 95-635 0e+00

Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1.


Pssm-ID: 404688  Cd Length: 543  Bit Score: 1168.33  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168     95 VCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGR 174
Cdd:pfam13844   1 VCDWTDYESRMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHDFRKAIAARHANLCLEKIQILHKPPYKFPKDLSLSGGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    175 LRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHI 254
Cdd:pfam13844  81 LRIGYVSSDFGNHPTSHLMQSIPGFHDREKVEVFCYALSPDDGTNFRSKIARESEHFVDLSQIPCNGKAADRIHADGIHI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    255 LVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHL 334
Cdd:pfam13844 161 LVNMNGYTKGARNEIFALRPAPIQVMWLGYPGTSGASFMDYIITDAVTSPLELADQYSEKLAYMPHTFFIGDHRQMFPHL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    335 KKKAVIDFKSNG-HIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPD--GGDNADSSNTALNMPVIPMNTiAEAVIEMINR 411
Cdd:pfam13844 241 KERAIVTDKSDGtKVRDNVAVVNATDLKPLLEKTEVKDKVKEVVVVetTGNSRDSSKVEVVLPVIELPT-TEPIESMIQS 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    412 GQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSV 491
Cdd:pfam13844 320 GQIQTSVNGVVVQNGLATTQTNNKAATGEEVPSSIVVTTRQQYGLPDDAIVYCNFNQLYKIDPPTLEMWVNILKRVPNSV 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    492 LWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLA 571
Cdd:pfam13844 400 LWLLRFPAVGEPNILATAQELGIPPGRIVFSNVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTLPGETLA 479

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6562168    572 SRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMEL 635
Cdd:pfam13844 480 SRVAASQLATLGCPELIAKSRQEYEDIAVKLGTDREYLKAIRAKVWKARTTSPLFNVKQYTQDL 543
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 2-646 0e+00

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 544.59  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:COG3914 134 ALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDN 213

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168   82 PDAYCNLAHCLQIVCDWTDYDERMKKLvsivaDQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKinvlHKPP 161
Cdd:COG3914 214 ADAHSNLLFALRQACDWEVYDRFEELL-----AALARGPSELSPFALLYLPDDDPAELLALARAWAQLVAAA----AAPE 284

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168  162 YEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDgTNFRVKVMAEANHFIDLSQIPcNG 241
Cdd:COG3914 285 LPPPPNPRDPDRKLRIGYVSADFRRHAVGYLLEPLLEHHDRSRFEIYAYSTGPDD-DALTQRLRAAADHWRDIPGLS-DE 362

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168  242 KAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHT 321
Cdd:COG3914 363 EAAELIRADGIDILVDLSGHTAGNRLGVFALRPAPVQVSWLGYPGTTGLPAIDYFIADPYVLPPGAEAYYSEKLVRLPGS 442

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168  322 FFigdhanmfphlkkkavidfksnghiydnrivlngidlkafldslpdvkivkmkCPDGGDNAdssntalnmPVIPmnti 401
Cdd:COG3914 443 YL-----------------------------------------------------CYQPNDRA---------PEVA---- 456

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168  402 aeavieminrgqiqitingfsisnglattqinnkaatgeEVPrtiivtTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWA 481
Cdd:COG3914 457 ---------------------------------------PLP------TRADLGLPEGAVVFGSFNNLYKITPEVFALWA 491

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168  482 NILKRVPNSVLWLLRFP-AVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGT 560
Cdd:COG3914 492 RILKAVPNSVLLLKGGGlPEARERLRAAAAARGVDPDRLIFLPRLPRAEHLARYALADLFLDTFPYNGGTTTLEALWMGV 571

                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168  561 PMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYL 640
Cdd:COG3914 572 PVVTLAGETFASRVGASLLTALGLPELIATSEEEYVALAVALATDPELLAALRAKLRERRQTSPLFDTPRFARDLEAAYR 651


                ....*.
gi 6562168  641 QMWEHY 646
Cdd:COG3914 652 QMWQRW 657
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
2-93 8.70e-26

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 106.63  E-value: 8.70e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:COG0457  30 DYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDD 109

                        90
                ....*....|..
gi 6562168   82 PDAYCNLAHCLQ 93
Cdd:COG0457 110 AEALYNLGLALL 121
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 3-113 2.95e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 63.56  E-value: 2.95e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168      3 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFP 82
Cdd:TIGR02917 148 YEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNI 227

                          90       100       110
                  ....*....|....*....|....*....|.
gi 6562168     83 DAYCNLAhclQIVCDWTDYDERMKKLVSIVA 113
Cdd:TIGR02917 228 AVLLALA---TILIEAGEFEEAEKHADALLK 255
TPR_11 pfam13414
TPR repeat;
57-90 9.92e-08

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 48.62  E-value: 9.92e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 6562168     57 IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH 90
Cdd:pfam13414   3 AYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGL 36
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 14-47 9.66e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.82  E-value: 9.66e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 6562168      14 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAF 47
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 3-77 1.09e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 48.01  E-value: 1.09e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6562168    3 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINP-AFADAHSNLASIHkdSGNipEAIASYRTALKL 77
Cdd:cd24142  23 LQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPdGGYEKYLYLGQLS--GGE--EALQYYEKGIEI 94
PRK09782 PRK09782
bacteriophage N4 receptor, outer membrane subunit; Provisional
 28-121 1.12e-05

bacteriophage N4 receptor, outer membrane subunit; Provisional


Pssm-ID: 236624 [Multi-domain]  Cd Length: 987  Bit Score: 48.76  E-value: 1.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    28 QDVQGALQCYTRAIQINPAfADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLqivCDWTDYDERMKK 107
Cdd:PRK09782 590 GQPELALNDLTRSLNIAPS-ANAYVARATIYRQRHNVPAAVSDLRAALELEPNNSNYQAALGYAL---WDSGDIAQSREM 665

                         90
                 ....*....|....
gi 6562168   108 LVSIVADQLEKNRL 121
Cdd:PRK09782 666 LERAHKGLPDDPAL 679
spiralin_repeat NF038028
spiralin repeat; The spiralin repeat is a domain that appears once in spiralin (the major ...
 369-449 3.92e-03

spiralin repeat; The spiralin repeat is a domain that appears once in spiralin (the major lipoprotein of Spiroplasma species) and up to six times in related proteins.


Pssm-ID: 468319  Cd Length: 88  Bit Score: 36.88  E-value: 3.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168   369 DVKIVKMKCPDGGDNADSSNTALNMpvipMNTIAEAVIEMIN-RGQIQITINGFSISNglattqiNNKAATGEEVPRTII 447
Cdd:NF038028   1 DISDVTVPDIKVIADPDVTYDELNA----NNTIIKAVITAINkKLNITVTTKDFTITN-------DNDKEGNQSAGTVVE 69


                 ..
gi 6562168   448 VT 449
Cdd:NF038028  70 FT 71
 
Name Accession Description Interval E-value
Glyco_transf_41 pfam13844
Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked ...
 95-635 0e+00

Glycosyl transferase family 41; This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1.


Pssm-ID: 404688  Cd Length: 543  Bit Score: 1168.33  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168     95 VCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGR 174
Cdd:pfam13844   1 VCDWTDYESRMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHDFRKAIAARHANLCLEKIQILHKPPYKFPKDLSLSGGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    175 LRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHI 254
Cdd:pfam13844  81 LRIGYVSSDFGNHPTSHLMQSIPGFHDREKVEVFCYALSPDDGTNFRSKIARESEHFVDLSQIPCNGKAADRIHADGIHI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    255 LVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHL 334
Cdd:pfam13844 161 LVNMNGYTKGARNEIFALRPAPIQVMWLGYPGTSGASFMDYIITDAVTSPLELADQYSEKLAYMPHTFFIGDHRQMFPHL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    335 KKKAVIDFKSNG-HIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPD--GGDNADSSNTALNMPVIPMNTiAEAVIEMINR 411
Cdd:pfam13844 241 KERAIVTDKSDGtKVRDNVAVVNATDLKPLLEKTEVKDKVKEVVVVetTGNSRDSSKVEVVLPVIELPT-TEPIESMIQS 319

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    412 GQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSV 491
Cdd:pfam13844 320 GQIQTSVNGVVVQNGLATTQTNNKAATGEEVPSSIVVTTRQQYGLPDDAIVYCNFNQLYKIDPPTLEMWVNILKRVPNSV 399

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    492 LWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLA 571
Cdd:pfam13844 400 LWLLRFPAVGEPNILATAQELGIPPGRIVFSNVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTLPGETLA 479

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6562168    572 SRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMEL 635
Cdd:pfam13844 480 SRVAASQLATLGCPELIAKSRQEYEDIAVKLGTDREYLKAIRAKVWKARTTSPLFNVKQYTQDL 543
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 2-646 0e+00

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 544.59  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:COG3914 134 ALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDN 213

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168   82 PDAYCNLAHCLQIVCDWTDYDERMKKLvsivaDQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKinvlHKPP 161
Cdd:COG3914 214 ADAHSNLLFALRQACDWEVYDRFEELL-----AALARGPSELSPFALLYLPDDDPAELLALARAWAQLVAAA----AAPE 284

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168  162 YEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDgTNFRVKVMAEANHFIDLSQIPcNG 241
Cdd:COG3914 285 LPPPPNPRDPDRKLRIGYVSADFRRHAVGYLLEPLLEHHDRSRFEIYAYSTGPDD-DALTQRLRAAADHWRDIPGLS-DE 362

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168  242 KAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHT 321
Cdd:COG3914 363 EAAELIRADGIDILVDLSGHTAGNRLGVFALRPAPVQVSWLGYPGTTGLPAIDYFIADPYVLPPGAEAYYSEKLVRLPGS 442

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168  322 FFigdhanmfphlkkkavidfksnghiydnrivlngidlkafldslpdvkivkmkCPDGGDNAdssntalnmPVIPmnti 401
Cdd:COG3914 443 YL-----------------------------------------------------CYQPNDRA---------PEVA---- 456

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168  402 aeavieminrgqiqitingfsisnglattqinnkaatgeEVPrtiivtTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWA 481
Cdd:COG3914 457 ---------------------------------------PLP------TRADLGLPEGAVVFGSFNNLYKITPEVFALWA 491

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168  482 NILKRVPNSVLWLLRFP-AVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGT 560
Cdd:COG3914 492 RILKAVPNSVLLLKGGGlPEARERLRAAAAARGVDPDRLIFLPRLPRAEHLARYALADLFLDTFPYNGGTTTLEALWMGV 571

                       570       580       590       600       610       620       630       640
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168  561 PMVTMPGETLASRVAASQLTCLGCLELIAKNRQEYEDIAVKLGTDLEYLKKVRGKVWKQRISSPLFNTKQYTMELERLYL 640
Cdd:COG3914 572 PVVTLAGETFASRVGASLLTALGLPELIATSEEEYVALAVALATDPELLAALRAKLRERRQTSPLFDTPRFARDLEAAYR 651


                ....*.
gi 6562168  641 QMWEHY 646
Cdd:COG3914 652 QMWQRW 657
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
2-93 8.70e-26

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 106.63  E-value: 8.70e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:COG0457  30 DYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDD 109

                        90
                ....*....|..
gi 6562168   82 PDAYCNLAHCLQ 93
Cdd:COG0457 110 AEALYNLGLALL 121
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
2-93 1.99e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 102.78  E-value: 1.99e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:COG0457  64 DYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDD 143

                        90
                ....*....|..
gi 6562168   82 PDAYCNLAHCLQ 93
Cdd:COG0457 144 ADALYNLGIALE 155
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
7-93 5.75e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 98.54  E-value: 5.75e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    7 IRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYC 86
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80


                ....*..
gi 6562168   87 NLAHCLQ 93
Cdd:COG0457  81 NLGLALQ 87
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 3-115 4.93e-19

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 83.70  E-value: 4.93e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    3 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFP 82
Cdd:COG4783  27 LEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHP 106

                        90       100       110
                ....*....|....*....|....*....|...
gi 6562168   83 DAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQ 115
Cdd:COG4783 107 EAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
2-117 8.19e-18

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 83.04  E-value: 8.19e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:COG4785  95 DFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPND 174

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 6562168   82 PDAYCNLAHCLQIVcdwtDYDERMKKLVSIVADQLE 117
Cdd:COG4785 175 PERALWLYLAERKL----DPEKALALLLEDWATAYL 206
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 3-89 5.53e-17

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 77.74  E-value: 5.53e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    3 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFP 82
Cdd:COG4235   6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85


                ....*..
gi 6562168   83 DAYCNLA 89
Cdd:COG4235  86 EALYLLG 92
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 3-143 1.02e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.93  E-value: 1.02e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    3 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFP 82
Cdd:COG2956 133 LERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYL 212

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 6562168   83 DAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLpsvhphhSMLYPLSHGFRKAIA 143
Cdd:COG2956 213 PALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLAL-------ADLLERKEGLEAALA 266
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
2-80 1.78e-16

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 75.21  E-value: 1.78e-16
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQcYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 80
Cdd:COG3063  14 YYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 2-79 7.85e-16

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 75.38  E-value: 7.85e-16
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 79
Cdd:COG5010  76 LLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
2-85 1.90e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.58  E-value: 1.90e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:COG0457  98 DYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAA 177


                ....
gi 6562168   82 PDAY 85
Cdd:COG0457 178 LLAA 181
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 2-81 5.56e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 72.15  E-value: 5.56e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:COG4783  60 LLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 13-92 1.59e-14

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 71.53  E-value: 1.59e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168   13 FADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL 92
Cdd:COG5010  53 AFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALL 132
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 3-85 1.65e-14

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 70.81  E-value: 1.65e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    3 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFP 82
Cdd:COG4235  40 YEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119


                ...
gi 6562168   83 DAY 85
Cdd:COG4235 120 PAR 122
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
26-117 2.23e-14

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 69.04  E-value: 2.23e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168   26 EMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIAsYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERM 105
Cdd:COG3063   4 KLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYL 82

                        90
                ....*....|..
gi 6562168  106 KKLVSIVADQLE 117
Cdd:COG3063  83 ERALELDPSALR 94
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
11-92 4.29e-14

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 71.87  E-value: 4.29e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168   11 PTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH 90
Cdd:COG4785  70 PDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGI 149


                ..
gi 6562168   91 CL 92
Cdd:COG4785 150 AL 151
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 2-98 1.16e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.68  E-value: 1.16e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:COG2956  30 LLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDD 109

                        90
                ....*....|....*..
gi 6562168   82 PDAYCNLAHCLQIVCDW 98
Cdd:COG2956 110 AEALRLLAEIYEQEGDW 126
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 2-89 1.93e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.91  E-value: 1.93e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:COG2956  98 LLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDC 177


                ....*...
gi 6562168   82 PDAYCNLA 89
Cdd:COG2956 178 ARALLLLA 185
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 2-119 1.95e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.91  E-value: 1.95e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDf 81
Cdd:COG2956 166 ALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS- 244

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 6562168   82 PDAYCNLAHCLQivcdwtdYDERMKKLVSIVADQLEKN 119
Cdd:COG2956 245 DDLLLALADLLE-------RKEGLEAALALLERQLRRH 275
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 14-92 2.56e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.44  E-value: 2.56e-12
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6562168   14 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL 92
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLAL 82
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 3-89 1.76e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.14  E-value: 1.76e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    3 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFP 82
Cdd:COG2956  65 HQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENA 144


                ....*..
gi 6562168   83 DAYCNLA 89
Cdd:COG2956 145 HAYCELA 151
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 3-113 2.95e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 63.56  E-value: 2.95e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168      3 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFP 82
Cdd:TIGR02917 148 YEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNI 227

                          90       100       110
                  ....*....|....*....|....*....|.
gi 6562168     83 DAYCNLAhclQIVCDWTDYDERMKKLVSIVA 113
Cdd:TIGR02917 228 AVLLALA---TILIEAGEFEEAEKHADALLK 255
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 33-92 5.51e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 57.71  E-value: 5.51e-10
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168   33 ALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL 92
Cdd:COG4235   2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEAL 61
TPR_11 pfam13414
TPR repeat;
57-90 9.92e-08

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 48.62  E-value: 9.92e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 6562168     57 IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAH 90
Cdd:pfam13414   3 AYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGL 36
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 28-89 1.32e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.58  E-value: 1.32e-07
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 6562168   28 QDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 89
Cdd:COG2956  22 GQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELA 83
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
2-92 2.04e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 52.22  E-value: 2.04e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAiQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:COG4785  28 ALLFAAVLALAIALADLALALAAAALAAAALAAERIDRA-LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDL 106

                        90
                ....*....|.
gi 6562168   82 PDAYCNLAHCL 92
Cdd:COG4785 107 AEAYNNRGLAY 117
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 4-84 3.46e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.55  E-value: 3.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168      4 KEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPD 83
Cdd:TIGR02917 591 NEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTE 670


                  .
gi 6562168     84 A 84
Cdd:TIGR02917 671 A 671
TPR_1 pfam00515
Tetratricopeptide repeat;
14-45 1.40e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 45.10  E-value: 1.40e-06
                          10        20        30
                  ....*....|....*....|....*....|..
gi 6562168     14 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINP 45
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNP 32
TPR_11 pfam13414
TPR repeat;
21-62 1.95e-06

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 44.77  E-value: 1.95e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 6562168     21 GNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSG 62
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 39-92 3.22e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 3.22e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....
gi 6562168   39 RAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL 92
Cdd:COG5010  45 AGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLY 98
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 3-84 3.73e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 46.14  E-value: 3.73e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    3 YKEAIRI----------SPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPA---FADAHSNLASIHKDSGNIPEAIA 69
Cdd:COG1729   9 YDEAIAAfkaflkrypnSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYLELGDYDKARA 88

                        90
                ....*....|....*
gi 6562168   70 SYRTALKLKPDFPDA 84
Cdd:COG1729  89 TLEELIKKYPDSEAA 103
TPR_12 pfam13424
Tetratricopeptide repeat;
14-80 4.31e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.07  E-value: 4.31e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6562168     14 ADAYSNMGNTLKEMQDVQGALQCYTRAIQI--------NPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 80
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 14-47 9.66e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.82  E-value: 9.66e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 6562168      14 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAF 47
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 3-77 1.09e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 48.01  E-value: 1.09e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6562168    3 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINP-AFADAHSNLASIHkdSGNipEAIASYRTALKL 77
Cdd:cd24142  23 LQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPdGGYEKYLYLGQLS--GGE--EALQYYEKGIEI 94
PRK09782 PRK09782
bacteriophage N4 receptor, outer membrane subunit; Provisional
 28-121 1.12e-05

bacteriophage N4 receptor, outer membrane subunit; Provisional


Pssm-ID: 236624 [Multi-domain]  Cd Length: 987  Bit Score: 48.76  E-value: 1.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168    28 QDVQGALQCYTRAIQINPAfADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLqivCDWTDYDERMKK 107
Cdd:PRK09782 590 GQPELALNDLTRSLNIAPS-ANAYVARATIYRQRHNVPAAVSDLRAALELEPNNSNYQAALGYAL---WDSGDIAQSREM 665

                         90
                 ....*....|....
gi 6562168   108 LVSIVADQLEKNRL 121
Cdd:PRK09782 666 LERAHKGLPDDPAL 679
TPR_1 pfam00515
Tetratricopeptide repeat;
48-81 1.48e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 42.02  E-value: 1.48e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 6562168     48 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 48-81 2.76e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 41.28  E-value: 2.76e-05
                           10        20        30
                   ....*....|....*....|....*....|....
gi 6562168      48 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPDF 81
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
57-92 4.18e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.85  E-value: 4.18e-05
                        10        20        30
                ....*....|....*....|....*....|....*.
gi 6562168   57 IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCL 92
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLL 36
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 2-57 6.88e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.07  E-value: 6.88e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASI 57
Cdd:COG4235  73 LLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 22-95 8.60e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.93  E-value: 8.60e-05
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6562168   22 NTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPD-FPDAYCNLAhclQIV 95
Cdd:cd24142   8 EELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDgGYEKYLYLG---QLS 79
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 1-89 1.00e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.84  E-value: 1.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168      1 MHYKEAIRISPTfADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 80
Cdd:TIGR02917 724 QAYRKALKRAPS-SQNAIKLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPD 802


                  ....*....
gi 6562168     81 FPDAYCNLA 89
Cdd:TIGR02917 803 NAVVLNNLA 811
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 48-80 1.03e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 39.81  E-value: 1.03e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 6562168     48 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 80
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 19-80 1.10e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 40.78  E-value: 1.10e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6562168     19 NMGNTLKEMQDVQGALQCYTRAIQIN---PAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 80
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPG 66
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 14-45 1.31e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 39.43  E-value: 1.31e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 6562168     14 ADAYSNMGNTLKEMQDVQGALQCYTRAIQINP 45
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDP 32
TPR_19 pfam14559
Tetratricopeptide repeat;
29-85 1.55e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 40.26  E-value: 1.55e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 6562168     29 DVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 85
Cdd:pfam14559   3 DYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYA 59
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 11-79 2.79e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 2.79e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6562168     11 PTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKP 79
Cdd:TIGR02917 462 PDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDP 530
TPR_17 pfam13431
Tetratricopeptide repeat;
2-35 3.19e-04

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 38.29  E-value: 3.19e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 6562168      2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQ 35
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 5-84 3.67e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.92  E-value: 3.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168      5 EAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDA 84
Cdd:TIGR02917 184 EVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLA 263
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 26-93 6.17e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.97  E-value: 6.17e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6562168   26 EMQDVQGALQCYTRAIQINPA---FADAHSNLASIHKDSGNIPEAIASYRTALKLKPD---FPDAYCNLAHCLQ 93
Cdd:COG1729   5 KAGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDspkAPDALLKLGLSYL 78
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 3-122 1.05e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 42.28  E-value: 1.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168      3 YKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFP 82
Cdd:TIGR00990 388 FDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAP 467

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 6562168     83 DAYCNLAhclQIVCDWTDYDERMKKLVSIVAdqLEKNRLP 122
Cdd:TIGR00990 468 DVYNYYG---ELLLDQNKFDEAIEKFDTAIE--LEKETKP 502
TPR_11 pfam13414
TPR repeat;
2-28 1.35e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.35e-03
                          10        20
                  ....*....|....*....|....*..
gi 6562168      2 HYKEAIRISPTFADAYSNMGNTLKEMQ 28
Cdd:pfam13414  16 AYKKALKLDPDNPEAYYNLGLAYYKLG 42
SNAP cd15832
Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family; Members of the ...
 14-74 2.26e-03

Soluble N-ethylmaleimide-sensitive factor (NSF) Attachment Protein family; Members of the soluble NSF attachment protein (SNAP) family are involved in intracellular membrane trafficking, including vesicular transport between the endoplasmic reticulum and Golgi apparatus. Higher eukaryotes contain three isoforms of SNAPs: alpha, beta, and gamma. Alpha-SNAP is universally present in eukaryotes and acts as an adaptor protein between SNARE (integral membrane SNAP receptor) and NSF for recruitment to the 20S complex. Beta-SNAP is brain-specific and shares high sequence identity (about 85%) with alpha-SNAP. Gamma-SNAP is weakly related (about 20-25% identity) to the two other isoforms, and is ubiquitous. It may help regulate the activity of the 20S complex. The X-ray structures of vertebrate gamma-SNAP and yeast Sec17, a SNAP family member, show similar all-helical structures consisting of an N-terminal extended twisted sheet of four Tetratricopeptide repeat (TPR)-like helical hairpins and a C-terminal helical bundle.


Pssm-ID: 276937 [Multi-domain]  Cd Length: 278  Bit Score: 40.26  E-value: 2.26e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6562168   14 ADAYSNMGNTLKEMqDVQGALQCYTRAIQI-------NPAfADAHSNLASIH-KDSGNIPEAIASYRTA 74
Cdd:cd15832  72 ANAYVEAAKCYKKV-DPQEAVNCLEKAIEIytemgrfRQA-AKHLKEIAELYeNELGDLDKAIEAYEQA 138
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
2-77 2.57e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.99  E-value: 2.57e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6562168    2 HYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKL 77
Cdd:COG0457 132 AYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
TPR_7 pfam13176
Tetratricopeptide repeat;
50-85 2.60e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 35.98  E-value: 2.60e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 6562168     50 AHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 85
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
TPR_8 pfam13181
Tetratricopeptide repeat;
48-80 2.90e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 35.45  E-value: 2.90e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 6562168     48 ADAHSNLASIHKDSGNIPEAIASYRTALKLKPD 80
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 33-85 3.01e-03

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 40.54  E-value: 3.01e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 6562168    33 ALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAY 85
Cdd:PLN03088  21 AVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAY 73
TPR_17 pfam13431
Tetratricopeptide repeat;
36-69 3.35e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 35.60  E-value: 3.35e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 6562168     36 CYTRAIQINPAFADAHSNLASIHKDSGNIPEAIA 69
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
spiralin_repeat NF038028
spiralin repeat; The spiralin repeat is a domain that appears once in spiralin (the major ...
 369-449 3.92e-03

spiralin repeat; The spiralin repeat is a domain that appears once in spiralin (the major lipoprotein of Spiroplasma species) and up to six times in related proteins.


Pssm-ID: 468319  Cd Length: 88  Bit Score: 36.88  E-value: 3.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6562168   369 DVKIVKMKCPDGGDNADSSNTALNMpvipMNTIAEAVIEMIN-RGQIQITINGFSISNglattqiNNKAATGEEVPRTII 447
Cdd:NF038028   1 DISDVTVPDIKVIADPDVTYDELNA----NNTIIKAVITAINkKLNITVTTKDFTITN-------DNDKEGNQSAGTVVE 69


                 ..
gi 6562168   448 VT 449
Cdd:NF038028  70 FT 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH