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Conserved domains on  [gi|4584541|emb|CAB40771|]
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3-hydroxyisobutyryl-coenzyme A hydrolase-like protein [Arabidopsis thaliana]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 19-369 1.41e-148

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 423.03  E-value: 1.41e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     19 VALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAAEIQKDKnTPLVQKVFTAEYT 98
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGG-GEAGRDFFREEYR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     99 LICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGgsVGAYLGLTGKR 178
Cdd:pfam16113  80 LNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGE--LGLYLALTGAR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    179 ISApSDALFVGLGTHYVPSEKLASLKEAIlsANLSEDPNQDIQATLSKYS-SNPESEAHLKSLLPHIESAFSSNkSIKET 257
Cdd:pfam16113 158 LNG-ADALAAGLATHYVPSARLPALEEAL--AALDWSDPADVDAVLAEFAeESDPPPSPLAAHREAIDRCFSAD-TVEEI 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    258 IEELKKyqqstESSVVEWANEALKGLEKGAPFSLYLTQKYFSnvacakskpENELATLNGVMKTEYRIALRSALRGDFAE 337
Cdd:pfam16113 234 IAALEA-----EADGDEWAAETLKTLRKRSPTSLKVTLRQLR---------RGRKLSLAECLRMEYRLALRCLRRPDFVE 299

                         330       340       350
                  ....*....|....*....|....*....|..
gi 4584541    338 GVRAVLIDKDQNPKWNPTSIEEVDENEVEALF 369
Cdd:pfam16113 300 GVRALLIDKDRNPKWSPATLEEVTDEMVDAYF 331
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 19-369 1.41e-148

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 423.03  E-value: 1.41e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     19 VALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAAEIQKDKnTPLVQKVFTAEYT 98
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGG-GEAGRDFFREEYR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     99 LICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGgsVGAYLGLTGKR 178
Cdd:pfam16113  80 LNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGE--LGLYLALTGAR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    179 ISApSDALFVGLGTHYVPSEKLASLKEAIlsANLSEDPNQDIQATLSKYS-SNPESEAHLKSLLPHIESAFSSNkSIKET 257
Cdd:pfam16113 158 LNG-ADALAAGLATHYVPSARLPALEEAL--AALDWSDPADVDAVLAEFAeESDPPPSPLAAHREAIDRCFSAD-TVEEI 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    258 IEELKKyqqstESSVVEWANEALKGLEKGAPFSLYLTQKYFSnvacakskpENELATLNGVMKTEYRIALRSALRGDFAE 337
Cdd:pfam16113 234 IAALEA-----EADGDEWAAETLKTLRKRSPTSLKVTLRQLR---------RGRKLSLAECLRMEYRLALRCLRRPDFVE 299

                         330       340       350
                  ....*....|....*....|....*....|..
gi 4584541    338 GVRAVLIDKDQNPKWNPTSIEEVDENEVEALF 369
Cdd:pfam16113 300 GVRALLIDKDRNPKWSPATLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 17-371 5.23e-125

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 363.76  E-value: 5.23e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDM--DIKYKsfLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAaEIQKDKNTPLVQKVFT 94
Cdd:PRK05617  11 GGVGVITLNRPKALNALSLEMirAIDAA--LDAWEDDDAVAAVVIEGAGERGFCAGGDIRALY-EAARAGDPLAADRFFR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    95 AEYTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGgsVGAYLGL 174
Cdd:PRK05617  88 EEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGA--LGTYLAL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   175 TGKRISAPsDALFVGLGTHYVPSEKLASLKEAILSANlSEDPNQDIQATLSKYSSNPESEAhLKSLLPHIESAFSSNkSI 254
Cdd:PRK05617 166 TGARISAA-DALYAGLADHFVPSADLPALLDALISLR-WDSGADVVDAALAAFATPAPASE-LAAQRAWIDECFAGD-TV 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   255 KETIEELkkyqqstESSVVEWANEALKGLEKGAPFSLYLTQKYFSnvacakskpENELATLNGVMKTEYRIALRSALRGD 334
Cdd:PRK05617 242 EDIIAAL-------EADGGEFAAKTADTLRSRSPTSLKVTLEQLR---------RARGLTLEECLRRELRLALAMLRSPD 305

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 4584541   335 FAEGVRAVLIDKDQNPKWNPTSIEEVDENEVEALFKP 371
Cdd:PRK05617 306 FVEGVRAVLIDKDRNPKWSPATLEDVTPEDVEAFFAP 342
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 17-200 3.86e-46

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 156.57  E-value: 3.86e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAEIQKDkntPLVQKVFTAE 96
Cdd:cd06558   7 GGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAALSDAG---EEARAFIREL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   97 YTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPgGGSVGAYLGLTG 176
Cdd:cd06558  83 QELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLV-GPARARELLLTG 161

                       170       180
                ....*....|....*....|....
gi 4584541  177 KRISAPsDALFVGLGTHYVPSEKL 200
Cdd:cd06558 162 RRISAE-EALELGLVDEVVPDEEL 184
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 17-200 5.57e-38

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 136.84  E-value: 5.57e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKgvaaEIQKDKNTPLVQKVFTAE 96
Cdd:COG1024   7 GGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLK----ELAAAADPEEARAFARGL 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   97 YTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGsVGAYLGLTG 176
Cdd:COG1024  82 QRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLA-RAKELLLTG 160

                       170       180
                ....*....|....*....|....
gi 4584541  177 KRISAPsDALFVGLGTHYVPSEKL 200
Cdd:COG1024 161 RRIDAE-EALELGLVNRVVPDDEL 183
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 17-181 5.19e-10

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 61.01  E-value: 5.19e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     17 NGVALITLDRTKA-LNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAAEIQKDKNTPL---VQKV 92
Cdd:TIGR02441  21 GDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLsqeGQEM 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     93 FTAeytlicaIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITE--RTVLAMPENGIGLFPDVGFSyiaAHSPGGGSVGA 170
Cdd:TIGR02441 101 FER-------IEKSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGT---QRLPKLTGVPA 170

                         170
                  ....*....|...
gi 4584541    171 YLG--LTGKRISA 181
Cdd:TIGR02441 171 ALDmmLTGKKIRA 183
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 19-369 1.41e-148

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 423.03  E-value: 1.41e-148
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     19 VALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAAEIQKDKnTPLVQKVFTAEYT 98
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAGG-GEAGRDFFREEYR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     99 LICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGgsVGAYLGLTGKR 178
Cdd:pfam16113  80 LNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGE--LGLYLALTGAR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    179 ISApSDALFVGLGTHYVPSEKLASLKEAIlsANLSEDPNQDIQATLSKYS-SNPESEAHLKSLLPHIESAFSSNkSIKET 257
Cdd:pfam16113 158 LNG-ADALAAGLATHYVPSARLPALEEAL--AALDWSDPADVDAVLAEFAeESDPPPSPLAAHREAIDRCFSAD-TVEEI 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    258 IEELKKyqqstESSVVEWANEALKGLEKGAPFSLYLTQKYFSnvacakskpENELATLNGVMKTEYRIALRSALRGDFAE 337
Cdd:pfam16113 234 IAALEA-----EADGDEWAAETLKTLRKRSPTSLKVTLRQLR---------RGRKLSLAECLRMEYRLALRCLRRPDFVE 299

                         330       340       350
                  ....*....|....*....|....*....|..
gi 4584541    338 GVRAVLIDKDQNPKWNPTSIEEVDENEVEALF 369
Cdd:pfam16113 300 GVRALLIDKDRNPKWSPATLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 17-371 5.23e-125

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 363.76  E-value: 5.23e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDM--DIKYKsfLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAaEIQKDKNTPLVQKVFT 94
Cdd:PRK05617  11 GGVGVITLNRPKALNALSLEMirAIDAA--LDAWEDDDAVAAVVIEGAGERGFCAGGDIRALY-EAARAGDPLAADRFFR 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    95 AEYTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGgsVGAYLGL 174
Cdd:PRK05617  88 EEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGA--LGTYLAL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   175 TGKRISAPsDALFVGLGTHYVPSEKLASLKEAILSANlSEDPNQDIQATLSKYSSNPESEAhLKSLLPHIESAFSSNkSI 254
Cdd:PRK05617 166 TGARISAA-DALYAGLADHFVPSADLPALLDALISLR-WDSGADVVDAALAAFATPAPASE-LAAQRAWIDECFAGD-TV 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   255 KETIEELkkyqqstESSVVEWANEALKGLEKGAPFSLYLTQKYFSnvacakskpENELATLNGVMKTEYRIALRSALRGD 334
Cdd:PRK05617 242 EDIIAAL-------EADGGEFAAKTADTLRSRSPTSLKVTLEQLR---------RARGLTLEECLRRELRLALAMLRSPD 305

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 4584541   335 FAEGVRAVLIDKDQNPKWNPTSIEEVDENEVEALFKP 371
Cdd:PRK05617 306 FVEGVRAVLIDKDRNPKWSPATLEDVTPEDVEAFFAP 342
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 18-377 1.38e-74

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 236.23  E-value: 1.38e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGsTSRAFCAGMDIKgVAAEIQKDKNTPLvqKVFTAEY 97
Cdd:PLN02874  20 RVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKG-AGRAFSAGGDLK-MFYDGRESDDSCL--EVVYRMY 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    98 TLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPggGSVGAYLGLTGK 177
Cdd:PLN02874  96 WLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLP--GHLGEYLALTGA 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   178 RISApSDALFVGLGTHYVPSEKLASLKEAILSANLSEDpnQDIQATLSKYSSNPE-SEAHLKSLLPHIESAFSsnksiKE 256
Cdd:PLN02874 174 RLNG-KEMVACGLATHFVPSEKLPELEKRLLNLNSGDE--SAVQEAIEEFSKDVQaDEDSILNKQSWINECFS-----KD 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   257 TIEEL-KKYQQSTESSVVEWANEALKGLEKGAPFSLYLTqkyfsnvacAKSKPENELATLNGVMKTEYRI---ALRSALR 332
Cdd:PLN02874 246 TVEEIiKAFESEASKTGNEWIKETLKGLRRSSPTGLKIT---------LRSIREGRKQSLAECLKKEFRLtmnILRSTVS 316

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 4584541   333 GDFAEGVRAVLIDKDQNPKWNPTSIEEVDENEVEALFKPLSPEVE 377
Cdd:PLN02874 317 DDVYEGIRALVIDKDNAPKWNPSTLDEVTDEKVDLVFQPFKAREE 361
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
 24-381 2.73e-63

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 207.91  E-value: 2.73e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    24 LDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAEIQkDKNTPLVQKVFTAEYTLICAI 103
Cdd:PLN02851  57 LNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGS-GRAFCSGADVVSLYHLIN-EGNVEECKLFFENLYKFVYLQ 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   104 AAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPggGSVGAYLGLTGKRISApS 183
Cdd:PLN02851 135 GTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLP--GYLGEYLALTGQKLNG-V 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   184 DALFVGLGTHYVPSEKLASLKEAiLSANLSEDPNQdIQATLSKYSS--NPESeahlKSLLPHIES--AFSSNKSIKETIE 259
Cdd:PLN02851 212 EMIACGLATHYCLNARLPLIEER-LGKLLTDDPAV-IEDSLAQYGDlvYPDK----SSVLHKIETidKCFGHDTVEEIIE 285

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   260 ELkkyQQSTESSVVEWANEALKGLEKGAPFSLYLTqkyfsnvacAKSKPENELATLNGVMKTEYRIAL---RSALRGDFA 336
Cdd:PLN02851 286 AL---ENEAASSYDEWCKKALKKIKEASPLSLKVT---------LQSIREGRFQTLDQCLAREYRISLcgvSKWVSGDFC 353

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 4584541   337 EGVRAVLIDKDQNPKWNPTSIEEVDENEVEALFKPLSPEVEELKV 381
Cdd:PLN02851 354 EGVRARLVDKDFAPKWDPPSLGEVSKDMVDCYFTPLDESESELEL 398
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
 17-377 4.34e-63

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 206.49  E-value: 4.34e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAEIQKDkNTPLVQKVFTAE 96
Cdd:PLN02988  17 SSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGH-GRAFCAGGDVAAVVRDIEQG-NWRLGANFFSDE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    97 YTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPggGSVGAYLGLTG 176
Cdd:PLN02988  95 YMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLP--GFFGEYVGLTG 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   177 KRISApSDALFVGLGTHYVPSEKLASLkEAILSANLSEDPNQdIQATLSKYSSN----PESEAHlksLLPHIESAFsSNK 252
Cdd:PLN02988 173 ARLDG-AEMLACGLATHFVPSTRLTAL-EADLCRIGSNDPTF-ASTILDAYTQHprlkPQSAYH---RLDVIDRCF-SRR 245

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   253 SIKETIEELKKyQQSTESSvvEWANEALKGLEKGAPFSLYLTqkyfsnvacAKSKPENELATLNGVMKTEYRI---ALRS 329
Cdd:PLN02988 246 TVEEIISALER-EATQEAD--GWISATIQALKKASPASLKIS---------LRSIREGRLQGVGQCLIREYRMvchVMKG 313

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 4584541   330 ALRGDFAEGVRAVLIDKDQNPKWNPTSIEEVDENEVEALFKPLSPEVE 377
Cdd:PLN02988 314 EISKDFVEGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFERVEEEEE 361
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
 24-381 3.17e-61

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 202.22  E-value: 3.17e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    24 LDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIkgVAAEIQKDKNTP-LVQKVFTAEYTLICA 102
Cdd:PLN02157  52 LNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGS-GRAFCAGGDI--VSLYHLRKRGSPdAIREFFSSLYSFIYL 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   103 IAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPggGSVGAYLGLTGKRISAp 182
Cdd:PLN02157 129 LGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLP--GRLGEYLGLTGLKLSG- 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   183 SDALFVGLGTHYVPSEKLASLKEAiLSANLSEDPNQdIQATLSKYS--SNPESEAHLKSlLPHIESAFSSNkSIKETIEE 260
Cdd:PLN02157 206 AEMLACGLATHYIRSEEIPVMEEQ-LKKLLTDDPSV-VESCLEKCAevAHPEKTGVIRR-IDLLEKCFSHD-TVEEIIDS 281

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   261 LKKYQQSTESSvveWANEALKGLEKGAPFSLYLTqkyfsnvacAKSKPENELATLNGVMKTEYRIALR---SALRGDFAE 337
Cdd:PLN02157 282 LEIEAGRRKDT---WCITTLRRLKESSPLSLKVA---------LRSIREGRLQTLDQCLIREYRMSLQgliGPMSGNFCE 349

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 4584541   338 GVRAVLIDKDQNPKWNPTSIEEVDENEVEALFKPLSPEVEELKV 381
Cdd:PLN02157 350 GVRARLIDKDEAPKWDPPSLEKVSEDMVDDYFCALTPTEPDLDL 393
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 17-200 3.86e-46

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 156.57  E-value: 3.86e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAEIQKDkntPLVQKVFTAE 96
Cdd:cd06558   7 GGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAALSDAG---EEARAFIREL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   97 YTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPgGGSVGAYLGLTG 176
Cdd:cd06558  83 QELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLV-GPARARELLLTG 161

                       170       180
                ....*....|....*....|....
gi 4584541  177 KRISAPsDALFVGLGTHYVPSEKL 200
Cdd:cd06558 162 RRISAE-EALELGLVDEVVPDEEL 184
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 17-200 5.57e-38

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 136.84  E-value: 5.57e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKgvaaEIQKDKNTPLVQKVFTAE 96
Cdd:COG1024   7 GGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLK----ELAAAADPEEARAFARGL 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   97 YTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGsVGAYLGLTG 176
Cdd:COG1024  82 QRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLA-RAKELLLTG 160

                       170       180
                ....*....|....*....|....
gi 4584541  177 KRISAPsDALFVGLGTHYVPSEKL 200
Cdd:COG1024 161 RRIDAE-EALELGLVNRVVPDDEL 183
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 17-207 2.85e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 97.63  E-value: 2.85e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMdikYKSF---LDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAeiQKDKNTPLVQKVF 93
Cdd:PRK06688  13 DGVLTITINRPDKKNALTAAM---YQALadaLEAAATDPAVRVVVLTGA-GRAFSAGGDIKDFPK--APPKPPDELAPVN 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    94 TAeytlICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPgGGSVGAYLG 173
Cdd:PRK06688  87 RF----LRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLI-GRARAAEML 161

                        170       180       190
                 ....*....|....*....|....*....|....
gi 4584541   174 LTGKRISAPsDALFVGLGTHYVPSEKLASLKEAI 207
Cdd:PRK06688 162 LLGEPLSAE-EALRIGLVNRVVPAAELDAEADAQ 194
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 17-211 2.45e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 92.10  E-value: 2.45e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAA--EIQKDKNTPLVQKVft 94
Cdd:PRK07657  12 PHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGmnEEQVRHAVSLIRTT-- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    95 aeytlICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSvGAYLGL 174
Cdd:PRK07657  90 -----MEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGR-AKELIY 163

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 4584541   175 TGKRISApSDALFVGLGTHYVPSEKLASLKEAI---LSAN 211
Cdd:PRK07657 164 TGRRISA-QEAKEIGLVEFVVPAHLLEEKAIEIaekIASN 202
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 18-270 5.51e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 90.99  E-value: 5.51e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAEIQKDkntplVQKVFtaeY 97
Cdd:PRK06072   9 GYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGE-GRAFCVGADLSEFAPDFAID-----LRETF---Y 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    98 TLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHspgggsvgaylgLTGK 177
Cdd:PRK06072  80 PIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLK------------LTGQ 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   178 RIsapSDALFVGLGTHYVPSEKLASLKeailsanLSEDPNQDIQATLSKYSSNPeseahlksLLPHIESAFSSNKSIKET 257
Cdd:PRK06072 148 RF---YEILVLGGEFTAEEAERWGLLK-------ISEDPLSDAEEMANRISNGP--------FQSYIAAKRMINLVLYND 209

                        250
                 ....*....|...
gi 4584541   258 IEELKKYQQSTES 270
Cdd:PRK06072 210 LEEFLEYESAIQG 222
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 15-210 1.65e-18

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 83.95  E-value: 1.65e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     15 FPNGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAE--IQKDKNTPLVQKV 92
Cdd:pfam00378   2 INAGVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGG-DKAFCAGADLKEMYGEgpAHQALYRENVLDL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     93 FTAEYTLicaiaayKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPgGGSVGAYL 172
Cdd:pfam00378  81 WTLLYTC-------PKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRII-GHSKAMEM 152

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 4584541    173 GLTGKRISApSDALFVGLGTHYVPSEKLasLKEAILSA 210
Cdd:pfam00378 153 LLLGRRISA-QEALKWGLVDKVVPEDQL--LDEARELA 187
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
18-200 2.37e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 83.65  E-value: 2.37e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAAEIQKDKNTPLVQKVFTAEy 97
Cdd:PRK05980  12 GIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADVALRDFVRRGQ- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    98 TLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVG----FSYIAahspgGGSVGAYLG 173
Cdd:PRK05980  91 AMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGgtqrLPRLA-----GRKRALELL 165

                        170       180
                 ....*....|....*....|....*..
gi 4584541   174 LTGKRISaPSDALFVGLGTHYVPSEKL 200
Cdd:PRK05980 166 LTGDAFS-AERALEIGLVNAVVPHEEL 191
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 18-250 1.01e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 76.23  E-value: 1.01e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAAeiQKDKNTPlvQKVF---T 94
Cdd:PRK06494  13 HVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQAA--GGKRGWP--ESGFgglT 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    95 AEYTLicaiaayKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLgL 174
Cdd:PRK06494  89 SRFDL-------DKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMI-L 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   175 TGKRISAPsDALFVGLGTHYVPSEKLASLKEA-----ILSANLSedpnqdIQATlskyssnpeSEAHLKSLLPHIESAFS 249
Cdd:PRK06494 161 TGRRVTAR-EGLELGFVNEVVPAGELLAAAERwaddiLACSPLS------IRAS---------KQAVYRGLEVSLEEAIT 224


                 .
gi 4584541   250 S 250
Cdd:PRK06494 225 A 225
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 18-210 2.43e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 75.13  E-value: 2.43e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAAEIQKDKNTPLVQKVFTAEY 97
Cdd:PRK06127  20 GLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESRSDAEAVAAYEQAVEAAQ 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    98 TlicAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLfpdvGFSYIAAH---SPGGGSVGAYLGL 174
Cdd:PRK06127 100 A---ALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGL----GYGYDGVKnlvDLVGPSAAKDLFY 172

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 4584541   175 TGKRISApSDALFVGLGTHYVPSEKLASLKEAILSA 210
Cdd:PRK06127 173 TARRFDA-AEALRIGLVHRVTAADDLETALADYAAT 207
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
18-211 8.36e-15

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 73.63  E-value: 8.36e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVA--AEIQKDKNTPLVQKVFTA 95
Cdd:PRK05809  13 HIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKdlNEEEGRKFGLLGNKVFRK 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    96 EYTLicaiaayKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGsVGAYLGLT 175
Cdd:PRK05809  93 LENL-------DKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPG-KAKELIYT 164

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 4584541   176 GKRISApSDALFVGLGTHYVPSEKLasLKEAILSAN 211
Cdd:PRK05809 165 GDMINA-EEALRIGLVNKVVEPEKL--MEEAKALAN 197
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 18-227 2.77e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 71.93  E-value: 2.77e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAEiqkdkntPLVQKVFTAEY 97
Cdd:PRK06190  13 RVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGA-DPAFCAGLDLKELGGD-------GSAYGAQDALP 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    98 TLICAIAAYKKPYISLMDG--ITMGFGLGLsgHGRYRVITERTVLAMPENGIGLFPDVGFSyiaAHSPggGSVGAY---- 171
Cdd:PRK06190  85 NPSPAWPAMRKPVIGAINGaaVTGGLELAL--ACDILIASERARFADTHARVGILPGWGLS---VRLP--QKVGIGrarr 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 4584541   172 LGLTGKRISApSDALFVGLGTHYVPSEKLasLKEAI-LSANLSEDPnqdiQATLSKY 227
Cdd:PRK06190 158 MSLTGDFLDA-ADALRAGLVTEVVPHDEL--LPRARrLAASIAGNN----PAAVRAL 207
PLN02600 PLN02600
enoyl-CoA hydratase
 17-197 3.49e-14

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 71.76  E-value: 3.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKgvaaeiQKDKNTPL-VQKVFTA 95
Cdd:PLN02600   3 SGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLK------ERRKMSPSeVQKFVNS 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    96 EYTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVG----FSYIAahspgGGSVGAY 171
Cdd:PLN02600  77 LRSTFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGgtqrLPRLV-----GRSRAKE 151

                        170       180
                 ....*....|....*....|....*.
gi 4584541   172 LGLTGKRISApSDALFVGLGTHYVPS 197
Cdd:PLN02600 152 LIFTGRRIGA-REAASMGLVNYCVPA 176
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 14-200 7.81e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 70.89  E-value: 7.81e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    14 VFPNGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGV----AAEIQKDKNTPLV 89
Cdd:PRK06210  11 VADSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGA-GRGFCAGADMGELqtidPSDGRRDTDVRPF 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    90 QKVFTAEYTLICA-IAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGsV 168
Cdd:PRK06210  90 VGNRRPDYQTRYHfLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHA-N 168

                        170       180       190
                 ....*....|....*....|....*....|..
gi 4584541   169 GAYLGLTGKRISApSDALFVGLGTHYVPSEKL 200
Cdd:PRK06210 169 ALDLLLSARTFYA-EEALRLGLVNRVVPPDEL 199
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 17-207 8.43e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 67.77  E-value: 8.43e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGsTSRAFCAGMDIKGVAA----EIQKDKNTPLVQkv 92
Cdd:PRK08138  16 DGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTG-GEKVFAAGADIKEFATagaiEMYLRHTERYWE-- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    93 ftaeytlicAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVgfsyiaahspgGGS----- 167
Cdd:PRK08138  93 ---------AIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGA-----------GGTqrlvr 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 4584541   168 -VGAY----LGLTGKRISAPsDALFVGLGTHYVPSEklASLKEAI 207
Cdd:PRK08138 153 aVGKFkamrMALTGCMVPAP-EALAIGLVSEVVEDE--QTLPRAL 194
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 17-209 1.56e-12

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 66.89  E-value: 1.56e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGsTSRAFCAGMDIKgvaaEIQKDKNTPLVQKVFTAE 96
Cdd:PRK08139  19 DGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAA-AGKAFCAGHDLK----EMRAARGLAYFRALFARC 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    97 YTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLF---PDVGFSYIAahspgGGSVGAYLG 173
Cdd:PRK08139  94 SRVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVALSRNV-----PRKQAMEML 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 4584541   174 LTGKRISApSDALFVGLGTHYVPSEKL----ASLKEAILS 209
Cdd:PRK08139 169 LTGEFIDA-ATAREWGLVNRVVPADALdaavARLAAVIAA 207
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 18-224 5.01e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 65.43  E-value: 5.01e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKAlNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIK---GVAAEIQKDKNTPLVQKVFT 94
Cdd:PRK07658  11 HVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGE-GRFFSAGADIKeftSVTEAEQATELAQLGQVTFE 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    95 AeytlicaIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPdvGFsyiaahspgGGS------V 168
Cdd:PRK07658  89 R-------VEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIP--GF---------AGTqrlpryV 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4584541   169 G----AYLGLTGKRISApSDALFVGLGTHYVPSEKLasLKEAI-LSANLSEDPNQDIQATL 224
Cdd:PRK07658 151 GkakaLEMMLTSEPITG-AEALKWGLVNGVFPEETL--LDDAKkLAKKIAGKSPATTRAVL 208
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 18-200 2.25e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 63.70  E-value: 2.25e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAEIQKDKNTPLVQKVFTAEY 97
Cdd:PRK05864  19 EIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGA-GRGFSSGADHKSAGVVPHVEGLTRPTYALRSMEL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    98 --TLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVL--AMPENGIGLfPDVGFSYIAAHSPgGGSVGAYLG 173
Cdd:PRK05864  98 ldDVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFraAGINNGLTA-SELGLSYLLPRAI-GSSRAFEIM 175

                        170       180
                 ....*....|....*....|....*..
gi 4584541   174 LTGKRISApSDALFVGLGTHYVPSEKL 200
Cdd:PRK05864 176 LTGRDVDA-EEAERIGLVSRQVPDEQL 201
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 14-154 2.91e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 63.13  E-value: 2.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    14 VFPNGVALITLDRTKALNAMNLDMDIKYKSFLDEW-ESDPRVkcVIVEGStSRAFCAGMDIK---GVAAEIQKDKNTPLV 89
Cdd:PRK07659  11 KYEGRVATIMLNRPEALNALDEPMLKELLQALKEVaESSAHI--VVLRGN-GRGFSAGGDIKmmlSSNDESKFDGVMNTI 87

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 4584541    90 QKVFTAEYTLicaiaayKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVG 154
Cdd:PRK07659  88 SEIVVTLYTM-------PKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGG 145
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 17-209 3.20e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 63.13  E-value: 3.20e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAAEiqkdknTPLVQKVFTAE 96
Cdd:PRK06143  15 RGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATL------DQASAEAFISR 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    97 YTLIC-AIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLfPDVgfsyI-AAHSPG--GGSVGAYL 172
Cdd:PRK06143  89 LRDLCdAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSV----IhAALLPRliGWARTRWL 163

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 4584541   173 GLTGKRISAPSdALFVGLGTHYVPSEKLASLKEAILS 209
Cdd:PRK06143 164 LLTGETIDAAQ-ALAWGLVDRVVPLAELDAAVERLAA 199
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 19-210 4.34e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 62.75  E-value: 4.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    19 VALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAEIQKDkntplvqkVFTAEY- 97
Cdd:PRK05862  14 VGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGS-EKAFAAGADIKEMADLSFMD--------VYKGDYi 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    98 TLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFS-----YIaahspgGGSVGAYL 172
Cdd:PRK05862  85 TNWEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSqrltrAV------GKAKAMDL 158

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 4584541   173 GLTGKRISApSDALFVGLGTHYVPSEKLasLKEAILSA 210
Cdd:PRK05862 159 CLTGRMMDA-AEAERAGLVSRVVPADKL--LDEALAAA 193
PLN02888 PLN02888
enoyl-CoA hydratase
 16-125 7.87e-11

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 62.08  E-value: 7.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    16 PNGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIkgVAAEiqkdknTPLVQKVFTA 95
Cdd:PLN02888  17 RNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGS-GRAFCSGVDL--TAAE------EVFKGDVKDV 87

                         90       100       110
                 ....*....|....*....|....*....|..
gi 4584541    96 EYTLICAIAAYKKPYISLMDG--ITMGFGLGL 125
Cdd:PLN02888  88 ETDPVAQMERCRKPIIGAINGfaITAGFEIAL 119
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 16-235 9.12e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 61.67  E-value: 9.12e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    16 PNGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGsTSRAFCAGMDIKGVAAEIQKDkntplVQKVFTA 95
Cdd:PRK05870  10 DDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTG-AGKAFCAGADLTALGAAPGRP-----AEDGLRR 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    96 EYTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLgLT 175
Cdd:PRK05870  84 IYDGFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAAL-LF 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   176 GKRISAPSdALFVGLGTHYVPSEKLASLKEAILSANLSEDPNQDIQATLSKYSSNPESEA 235
Cdd:PRK05870 163 GMRFDAEA-AVRHGLALMVADDPVAAALELAAGPAAAPRELVLATKASMRATASLAQHAA 221
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 18-198 5.16e-10

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 59.39  E-value: 5.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAaeiQKD----KNTPLVQkvf 93
Cdd:PRK09674  11 RVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGN-ARFFAAGADLNEMA---EKDlaatLNDPRPQ--- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    94 taeytLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPgGGSVGAYLG 173
Cdd:PRK09674  84 -----LWQRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSV-GKSLASQMV 157

                        170       180
                 ....*....|....*....|....*
gi 4584541   174 LTGKRISApSDALFVGLGTHYVPSE 198
Cdd:PRK09674 158 LTGESITA-QQAQQAGLVSEVFPPE 181
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 17-181 5.19e-10

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 61.01  E-value: 5.19e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     17 NGVALITLDRTKA-LNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAAEIQKDKNTPL---VQKV 92
Cdd:TIGR02441  21 GDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLsqeGQEM 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     93 FTAeytlicaIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITE--RTVLAMPENGIGLFPDVGFSyiaAHSPGGGSVGA 170
Cdd:TIGR02441 101 FER-------IEKSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGT---QRLPKLTGVPA 170

                         170
                  ....*....|...
gi 4584541    171 YLG--LTGKRISA 181
Cdd:TIGR02441 171 ALDmmLTGKKIRA 183
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 15-211 1.43e-09

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 58.48  E-value: 1.43e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    15 FPNGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSrAFCAGMDIKGVAAEIQkDKNTPLVQKVFT 94
Cdd:PRK09120  14 VEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGD-AWSAGMDLKEYFRETD-AQPEILQERIRR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    95 AEYTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSvGAYLGL 174
Cdd:PRK09120  92 EAYGWWRRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRD-ALYYIM 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 4584541   175 TGKRISAPsDALFVGLGTHYVPSEKL----ASLKEAILSAN 211
Cdd:PRK09120 171 TGETFTGR-KAAEMGLVNESVPLAQLrartRELAAKLLEKN 210
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 18-217 1.71e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 58.01  E-value: 1.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKcVIVEGSTSRAFCAGMDIKGVAAEIQKDKNTPLVQKVFTAEy 97
Cdd:PRK05995  13 QVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVR-AVVLAGAGKAFCAGADLNWMKKMAGYSDDENRADARRLAD- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    98 tLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSvgAYLGLTGK 177
Cdd:PRK05995  91 -MLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVIRAMGERAA--RRYFLTAE 167

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 4584541   178 RISApSDALFVGLGTHYVPSEKLASLKEAILSANLSEDPN 217
Cdd:PRK05995 168 RFDA-AEALRLGLVHEVVPAEALDAKVDELLAALVANSPQ 206
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
17-262 2.03e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 57.58  E-value: 2.03e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGsTSRAFCAGMDIKGVAAE-IQKDK--------NTP 87
Cdd:PRK07509  11 DGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSG-EGGAFCAGLDVKSVASSpGNAVKllfkrlpgNAN 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    88 LVQKVFTAEYTLICaiaaykkPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGfSYIAAHSPGGGS 167
Cdd:PRK07509  90 LAQRVSLGWRRLPV-------PVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMA-GTVSLRGLVRKD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   168 VGAYLGLTGKRISApSDALFVGLGTHyvpseklaslkeailsanLSEDPNQDIQATLSKYS-SNPESEAHLKSLLPHIES 246
Cdd:PRK07509 162 VARELTYTARVFSA-EEALELGLVTH------------------VSDDPLAAALALAREIAqRSPDAIAAAKRLINRSWT 222

                        250
                 ....*....|....*...
gi 4584541   247 AfsSNKSI--KETIEELK 262
Cdd:PRK07509 223 A--SVRALlaRESVEQIR 238
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 17-122 2.09e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 58.09  E-value: 2.09e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAEIQKDKNTPLVQkvFTAE 96
Cdd:PRK08260  12 DGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGA-GRAFCAGADLSAGGNTFDLDAPRTPVE--ADEE 88

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 4584541    97 YT--------------LICAIAAYKKPYISLMDGITMGFG 122
Cdd:PRK08260  89 DRadpsddgvrdgggrVTLRIFDSLKPVIAAVNGPAVGVG 128
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
18-149 2.42e-09

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 57.40  E-value: 2.42e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRtKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGsTSRAFCAGMDIKGVAAEIQKDKNTP----LVQKVF 93
Cdd:PRK06495  13 HVAVVTLDN-PPVNALSRELRDELIAVFDEISERPDVRVVVLTG-AGKVFCAGADLKGRPDVIKGPGDLRahnrRTRECF 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 4584541    94 TaeytlicAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGL 149
Cdd:PRK06495  91 H-------AIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL 139
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
15-238 3.10e-09

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 57.05  E-value: 3.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    15 FPNGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDP-RVKCVIVEGStSRAFCAGMDIKGVAAEIQKDKNTPLVQKVF 93
Cdd:PRK05981  10 FDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGA-GRGFCTGANLQGRGSGGRESDSGGDAGAAL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    94 TAEYT-LICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSvGAYL 172
Cdd:PRK05981  89 ETAYHpFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKAR-AMEL 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 4584541   173 GLTGKRISAPSdALFVGLGTHYVPSEKLasLKEAI-LSANLSEDPNQDIQATLSKYSSNPESEAHLK 238
Cdd:PRK05981 168 SLLGEKLPAET-ALQWGLVNRVVDDAEL--MAEAMkLAHELANGPTVALGLIRKLYWDSPENDFEEQ 231
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 17-143 3.33e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 56.92  E-value: 3.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIK----------GVAAEIQKDKnt 86
Cdd:PRK06144  16 GGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAqfrafstaedAVAYERRIDR-- 93

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 4584541    87 plvqkvftaeytLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMP 143
Cdd:PRK06144  94 ------------VLGALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP 138
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
18-182 5.98e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 56.15  E-value: 5.98e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSrAFCAGMDIKGVAAeiqkdKNTPLVQKVFTAEY 97
Cdd:PRK08252  12 RVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGG-TFCAGMDLKAFAR-----GERPSIPGRGFGGL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    98 TLicaiAAYKKPYISLMDGITMGFGLGLsghgryrVITERTVLAMPENGIGLfPDVGFSYIAAhspGGG----------S 167
Cdd:PRK08252  86 TE----RPPRKPLIAAVEGYALAGGFEL-------ALACDLIVAARDAKFGL-PEVKRGLVAA---GGGllrlprripyH 150

                        170
                 ....*....|....*
gi 4584541   168 VGAYLGLTGKRISAP 182
Cdd:PRK08252 151 IAMELALTGDMLTAE 165
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
21-196 1.75e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 55.11  E-value: 1.75e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    21 LITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSrAFCAGMDIKGVAAEIQKD-----KNTPLVQKVFTA 95
Cdd:PRK07799  17 IVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGG-AFCAGMDLKAATKKPPGDsfkdgSYDPSRIDALLK 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    96 EYTLicaiaayKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPdVGFSYIAAHSPGGGSVGAYLGLT 175
Cdd:PRK07799  96 GRRL-------TKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFP-MGGSAVRLVRQIPYTVACDLLLT 167

                        170       180
                 ....*....|....*....|.
gi 4584541   176 GKRISAPsDALFVGLGTHYVP 196
Cdd:PRK07799 168 GRHITAA-EAKEIGLIGHVVP 187
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
17-200 1.97e-08

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 54.70  E-value: 1.97e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKAlNAMNL----DMDIKYKSFLDewesDPRVKCVIVEGSTSRAFCAGMDIKGVAA-EIQKDKNTPlvqk 91
Cdd:PRK03580  11 GSILEITLDRPKA-NAIDAktsfAMGEVFLNFRD----DPELRVAIITGAGEKFFSAGWDLKAAAEgEAPDADFGP---- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    92 vftAEYTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGF-----SYIAAHspggg 166
Cdd:PRK03580  82 ---GGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGvlrlpKRLPPA----- 153

                        170       180       190
                 ....*....|....*....|....*....|....
gi 4584541   167 sVGAYLGLTGKRISApSDALFVGLGTHYVPSEKL 200
Cdd:PRK03580 154 -IANEMVMTGRRMDA-EEALRWGIVNRVVPQAEL 185
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
18-78 7.80e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 53.12  E-value: 7.80e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGsTSRAFCAGMDIKGVAA 78
Cdd:PRK08272  19 RIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSG-AGKGFCAGYDLSAYAE 78
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
18-210 2.21e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 51.61  E-value: 2.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCViVEGSTSRAFCAGMDIKGvAAEIQKDKNTPLVQKvfTAEY 97
Cdd:PRK07827  15 GVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAV-VLTHTGGTFCAGADLSE-AGGGGGDPYDAAVAR--AREM 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    98 T-LICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVgFSYIAAHSPGGGSVGAYLgLTG 176
Cdd:PRK07827  91 TaLLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAI-ISLTLLPRLSPRAAARYY-LTG 168

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 4584541   177 KRISApSDALFVGLGTHYV--PSEKLASLKEAILSA 210
Cdd:PRK07827 169 EKFGA-AEAARIGLVTAAAddVDAAVAALLADLRRG 203
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 16-153 4.65e-07

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 50.58  E-value: 4.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    16 PNGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAEIQKDKNTPLVQKVFTA 95
Cdd:PRK05674  13 PRGFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGR-GRHFSAGADLAWMQQSADLDYNTNLDDARELA 91

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 4584541    96 EytLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDV 153
Cdd:PRK05674  92 E--LMYNLYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAV 147
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
18-261 5.37e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 50.44  E-value: 5.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGsTSRAFCAGMDIKGVAAEIQKDKNTPLVQKVFTAEy 97
Cdd:PRK07468  14 GVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTG-AGKSFCAGGDLGWMRAQMTADRATRIEEARRLAM- 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    98 tLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSpgGGSVGAYLGLTGK 177
Cdd:PRK07468  92 -MLKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARM--GEANARRVFMSAR 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   178 RISApSDALFVGLGTHYVPSEKLASLKEAILSANLSEDPnqdiqatlskySSNPESEAHLKSLLPHIESAfssnkSIKET 257
Cdd:PRK07468 169 LFDA-EEAVRLGLLSRVVPAERLDAAVEAEVTPYLSCAP-----------GAVAAAKALVRALGAPIDEA-----VIDAT 231


                 ....
gi 4584541   258 IEEL 261
Cdd:PRK07468 232 IEAL 235
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
16-123 6.23e-07

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 50.40  E-value: 6.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    16 PNGVALITLDRTKALNAMNLDMdikYKSFLDEW---ESDPRVKCVIVEGStSRAFCAGMDIKGVAAEIQKDKntpLVQKV 92
Cdd:PRK07327  19 PPGVLEIVLNGPGALNAADARM---HRELADIWrdvDRDPDVRVVLIRGE-GKAFSAGGDLALVEEMADDFE---VRARV 91

                         90       100       110
                 ....*....|....*....|....*....|.
gi 4584541    93 FTAEYTLICAIAAYKKPYISLMDGITMGFGL 123
Cdd:PRK07327  92 WREARDLVYNVINCDKPIVSAIHGPAVGAGL 122
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 19-211 7.30e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 49.92  E-value: 7.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    19 VALITLDRTKAlNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDI-------KGVAAEiqkdkntplVQK 91
Cdd:PRK09076  13 VAILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLnlfadgdKAVARE---------MAR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    92 VFTAEYTlicAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPdvgfsyiaahsPGGGS---- 167
Cdd:PRK09076  83 RFGEAFE---ALSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLP-----------CAGGTqnlp 148

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 4584541   168 --VGAylG------LTGKRISAPSdALFVGLGTHYVPseKLASLKEAILSAN 211
Cdd:PRK09076 149 wlVGE--GwakrmiLCGERVDAAT-ALRIGLVEEVVE--KGEAREAALALAQ 195
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 17-190 1.54e-06

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 49.13  E-value: 1.54e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGsTSRAFCAGMDIKGV------AAEIQKDKNTPLVQ 90
Cdd:PLN02664  16 SSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSG-AGDHFCSGIDLKTLnsiseqSSSGDRGRSGERLR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    91 KVFTAEYTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGfsyIAAHSPG--GGSV 168
Cdd:PLN02664  95 RKIKFLQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLG---TLQRLPSivGYGN 171

                        170       180
                 ....*....|....*....|..
gi 4584541   169 GAYLGLTGKRISApSDALFVGL 190
Cdd:PLN02664 172 AMELALTGRRFSG-SEAKELGL 192
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
18-221 2.73e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 48.25  E-value: 2.73e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGsTSRAFCAGMDIKGVAAEIQKDKntplvqKVFTAEY 97
Cdd:PRK06023  15 GVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLG-TEGCFSAGNDMQDFLAAAMGGT------SFGSEIL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    98 TLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPGGGSVGAYLGLtGK 177
Cdd:PRK06023  88 DFLIALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLAL-GE 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 4584541   178 RISApSDALFVGLGTHYVPSEKLASLKEAiLSANLSEDPNQDIQ 221
Cdd:PRK06023 167 GFSA-EAAQEAGLIWKIVDEEAVEAETLK-AAEELAAKPPQALQ 208
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
13-200 4.39e-06

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 48.74  E-value: 4.39e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    13 NVFPNGVALITLD-RTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSRAFCAGMDIKGVAAEIQKDKNTPLV-- 89
Cdd:PRK11154  10 NVREDNIAVITIDvPGEKMNTLKAEFAEQVRAILKQLREDKELKGVVFISGKPDNFIAGADINMLAACKTAQEAEALArq 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    90 -QKVFtAEytlicaIAAYKKPYISLMDGITMGFGLGLSGHGRYRVIT--ERTVLAMPENGIGLFPDVGfsyiaahspG-- 164
Cdd:PRK11154  90 gQQLF-AE------IEALPIPVVAAIHGACLGGGLELALACHYRVCTddPKTVLGLPEVQLGLLPGSG---------Gtq 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 4584541   165 ------GGSVGAYLGLTGKRISaPSDALFVGLGTHYVPSEKL 200
Cdd:PRK11154 154 rlprliGVSTALDMILTGKQLR-AKQALKLGLVDDVVPHSIL 194
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 18-72 4.43e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 47.60  E-value: 4.43e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWEsDPRVKCVIVEGStSRAFCAGMD 72
Cdd:PRK08140  13 GVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGA-GRGFCAGQD 65
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
18-200 5.13e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 47.66  E-value: 5.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAM--NLDMDiKYKSFLDEWESDPRVKCVIVEGSTSrAFCAGMDIKGVAAEIQKDKNTPL------- 88
Cdd:PRK09245  12 HIVTLTMNRPETRNALsdNDAVD-ALVAACAAINADRSVRAVILTGAGT-AFSSGGNVKDMRARVGAFGGSPAdirqgyr 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    89 --VQKVFTAEYTLicaiaayKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFPDVGFSYIAAHSPgGG 166
Cdd:PRK09245  90 hgIQRIPLALYNL-------EVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRII-GM 161

                        170       180       190
                 ....*....|....*....|....*....|....
gi 4584541   167 SVGAYLGLTGKRISAPSdALFVGLGTHYVPSEKL 200
Cdd:PRK09245 162 ARAAEMAFTGDAIDAAT-ALEWGLVSRVVPADQL 194
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
17-195 6.10e-06

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 47.32  E-value: 6.10e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTsraFCAGMDIkgvaAEIQKDKNTPLVQ------ 90
Cdd:PRK08150  10 GGVATIGLNRPAKRNALNDGLIAALRAAFARLPEGVRAVVLHGEGDH---FCAGLDL----SELRERDAGEGMHhsrrwh 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    91 KVF-TAEYTLICAIAAYKkpyislmdGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFpdVGfsyiaahspGGGSV- 168
Cdd:PRK08150  83 RVFdKIQYGRVPVIAALH--------GAVVGGGLELASAAHIRVADESTYFALPEGQRGIF--VG---------GGGSVr 143

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 4584541   169 -----GAY----LGLTGKRISApSDALFVGLgTHYV 195
Cdd:PRK08150 144 vprliGVArmtdMMLTGRVYDA-QEGERLGL-AQYL 177
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
17-217 1.25e-05

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 46.50  E-value: 1.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKGVAAEIQKDKNTPLVQkvFTaE 96
Cdd:PRK08258  25 DGVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGA-GGNFCSGGDVHEIIGPLTKMDMPELLA--FT-R 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    97 YT--LICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMpengigLFPDVGFSyiaahspgGGSVGA-YL- 172
Cdd:PRK08258 101 MTgdLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAF------LFTRVGLA--------GADMGAcALl 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 4584541   173 ----GL--------TGKRISAPsDALFVGLGTHYVPSEKLASLKEAiLSANLSEDPN 217
Cdd:PRK08258 167 priiGQgrasellyTGRSMSAE-EGERWGFFNRLVEPEELLAEAQA-LARRLAAGPT 221
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
17-144 4.23e-05

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 44.58  E-value: 4.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    17 NGVALITLDRTKaLNAMNLDMDIKYKSFLDEWESDPRVKCVIV--EGstsRAFCAGMDIKgvaaEIQkdkNTPLVQKVFT 94
Cdd:PRK07938  10 PGIAEVTVDYPP-VNALPSAGWFALADAITAAGADPDTRVVVLraEG---RGFNAGVDIK----ELQ---ATPGFTALID 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 4584541    95 AE---YTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPE 144
Cdd:PRK07938  79 ANrgcFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPE 131
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
19-75 6.20e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 44.56  E-value: 6.20e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 4584541    19 VALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGStSRAFCAGMDIKG 75
Cdd:PRK12478  15 VATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGA-GRAFSGGYDFGG 70
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 1-210 3.16e-04

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 42.17  E-value: 3.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541     1 MAGA--GVDDFVKGNVFPNGVALITLDRtKALNAMNLDMDIKYKSFLDEWESDPRVKCVIVEGSTSR-AFCAGMDIKGVA 77
Cdd:PLN03214   2 PAPSppGATPGVRVDRRPGGIAVVWLAK-EPVNSMTLAMWRSLDDALTALENDPTVRGVVFASGLRRdVFTAGNDIAELY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    78 A---------EIQKDKNTPLVqKVFTAEYTLICAIAaykkpyislmdGITMGFGLGLSGHGRYRVITERTVLAMPENGIG 148
Cdd:PLN03214  81 ApktsaaryaEFWLTQTTFLV-RLLRSRLATVCAIR-----------GACPAGGCAVSLCCDYRLQTTEGTMGLNEVALG 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 4584541   149 LFPDVGFSYIAAHSPGGGSVGAYLGLTGkRISAPSDALFVGLGTHYVPSeklASLKEAILSA 210
Cdd:PLN03214 149 IPVPKFWARLFMGRVIDRKVAESLLLRG-RLVRPAEAKQLGLIDEVVPA---AALMEAAASA 206
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
45-207 1.16e-03

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 41.00  E-value: 1.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    45 LDEWESDPRVKCVIVegsTSR--AFCAGMDIKGVAAEIQKDKNTpLVQKVFTAEyTLICAIAAYKKPYISLMDGITMGFG 122
Cdd:PRK11730  43 LDALEAQSDLKGLLL---TSAkdAFIVGADITEFLSLFAAPEEE-LSQWLHFAN-SIFNRLEDLPVPTVAAINGYALGGG 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541   123 LGLSGHGRYRVITERTVLAMPENGIGLFPdvGFsyiaahspgGGSV------GAYLGL----TGKRISApSDALFVGLGT 192
Cdd:PRK11730 118 CECVLATDYRVASPDARIGLPETKLGIMP--GF---------GGTVrlprliGADNALewiaAGKDVRA-EDALKVGAVD 185

                        170       180
                 ....*....|....*....|
gi 4584541   193 HYVPSEKL-----ASLKEAI 207
Cdd:PRK11730 186 AVVAPEKLqeaalALLKQAI 205
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 17-75 1.43e-03

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 39.94  E-value: 1.43e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 4584541    17 NGVALITLDRTKALNAMNLDMDIKYKSFLDEWESDPRVKcVIVEGSTSRAFCAGMDIKG 75
Cdd:PRK08290  12 GRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVR-VIVLAGAGKHFSAGHDLGS 69
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
18-200 2.54e-03

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 39.28  E-value: 2.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    18 GVALITLDRTKALNAMNLDMDIKYKSFLDEWESDprVKCVIVEGsTSRAFCAGMDIKGVAAEIQKDKNTPlvqkvFTAE- 96
Cdd:PRK07112  13 DVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHA--ATIVVLEG-LPEVFCFGADFSAIAEKPDAGRADL-----IDAEp 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 4584541    97 -YTLICAIAAYKKPYISLMDGITMGFGLGLSGHGRYRVITERTVLAMPENGIGLFP---------DVGFSyiAAHspggg 166
Cdd:PRK07112  85 lYDLWHRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIPacvlpflirRIGTQ--KAH----- 157

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 4584541   167 svgaYLGLTGKRISApSDALFVGLGTHYVP-SEKL 200
Cdd:PRK07112 158 ----YMTLMTQPVTA-QQAFSWGLVDAYGAnSDTL 187
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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