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Conserved domains on  [gi|1789575434|emb|CAA0409765|]
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unnamed protein product [Arabidopsis thaliana]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 10789277)

class I SAM-dependent methyltransferase is an enzyme that uses S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyl transfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:0008168|GO:1904047
PubMed:  12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 92-249 9.99e-19

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


:

Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 80.42  E-value: 9.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434  92 YSAVPLRYEMAQRMVGSVGDwSSVKTALDLGCGRGILLNAVATQlkktgsSGRVVGLDRS--MtttLSTLRtAHIEGVQE 169
Cdd:COG2226     1 FDRVAARYDGREALLAALGL-RPGARVLDLGCGTGRLALALAER------GARVTGVDISpeM---LELAR-ERAAEAGL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 170 YVTCREGDVRRLPFSDNYFDVVVSAVFLHTIgkeygqktveaaAERMRVLGEAVRVLKPGGVGVVWDLV--HVPEYVRRL 247
Cdd:COG2226    70 NVEFVVGDAEDLPFPDGSFDLVISSFVLHHL------------PDPERALAEIARVLKPGGRLVVVDFSppDLAELEELL 137


                  ..
gi 1789575434 248 QE 249
Cdd:COG2226   138 AE 139
 
Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 92-249 9.99e-19

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 80.42  E-value: 9.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434  92 YSAVPLRYEMAQRMVGSVGDwSSVKTALDLGCGRGILLNAVATQlkktgsSGRVVGLDRS--MtttLSTLRtAHIEGVQE 169
Cdd:COG2226     1 FDRVAARYDGREALLAALGL-RPGARVLDLGCGTGRLALALAER------GARVTGVDISpeM---LELAR-ERAAEAGL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 170 YVTCREGDVRRLPFSDNYFDVVVSAVFLHTIgkeygqktveaaAERMRVLGEAVRVLKPGGVGVVWDLV--HVPEYVRRL 247
Cdd:COG2226    70 NVEFVVGDAEDLPFPDGSFDLVISSFVLHHL------------PDPERALAEIARVLKPGGRLVVVDFSppDLAELEELL 137


                  ..
gi 1789575434 248 QE 249
Cdd:COG2226   138 AE 139
PRK08317 PRK08317
hypothetical protein; Provisional
 117-236 3.64e-18

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 81.52  E-value: 3.64e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 117 TALDLGCGRGILLNAVAtqlKKTGSSGRVVGLDRSmtTTLSTLRTAHIEGVQEYVTCREGDVRRLPFSDNYFDVVVSavf 196
Cdd:PRK08317   22 RVLDVGCGPGNDARELA---RRVGPEGRVVGIDRS--EAMLALAKERAAGLGPNVEFVRGDADGLPFPDGSFDAVRS--- 93

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1789575434 197 lhtigkeygQKTVEAAAERMRVLGEAVRVLKPGGVGVVWD 236
Cdd:PRK08317   94 ---------DRVLQHLEDPARALAEIARVLRPGGRVVVLD 124
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 119-230 8.38e-18

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 76.83  E-value: 8.38e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 119 LDLGCGRGILLNAVATQLKktgssGRVVGLDRS--MtttLSTLRtAHIEGVQEYVTCREGDVRRLPFSDNYFDVVVSAVF 196
Cdd:pfam13649   2 LDLGCGTGRLTLALARRGG-----ARVTGVDLSpeM---LERAR-ERAAEAGLNVEFVQGDAEDLPFPDGSFDLVVSSGV 72

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1789575434 197 LHTIGKEygqktveaaaERMRVLGEAVRVLKPGG 230
Cdd:pfam13649  73 LHHLPDP----------DLEAALREIARVLKPGG 96
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 117-238 1.33e-11

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 60.14  E-value: 1.33e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 117 TALDLGCGRGILLNAVATQLKKtgssgRVVGLDRSMTTtLSTLRTAHIEGVQEYVTCREGDVRRLPF-SDNYFDVVVSAV 195
Cdd:cd02440     1 RVLDLGCGTGALALALASGPGA-----RVTGVDISPVA-LELARKAAAALLADNVEVLKGDAEELPPeADESFDVIISDP 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1789575434 196 FLHTIgkeygqktveaAAERMRVLGEAVRVLKPGGVGVVWDLV 238
Cdd:cd02440    75 PLHHL-----------VEDLARFLEEARRLLKPGGVLVLTLVL 106
MenG_MenH_UbiE TIGR01934
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ...
 117-237 4.17e-09

ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273884 [Multi-domain]  Cd Length: 223  Bit Score: 55.73  E-value: 4.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 117 TALDLGCGRGILLNAVAtqlKKTGSSGRVVGLDRSmTTTLSTLRTAHIegVQEYVTCREGDVRRLPFSDNYFDVVvsavf 196
Cdd:TIGR01934  42 KVLDVACGTGDLAIELA---KSAPDRGKVTGVDFS-SEMLEVAKKKSE--LPLNIEFIQADAEALPFEDNSFDAV----- 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1789575434 197 lhTIGkeYGQKTVeaaAERMRVLGEAVRVLKPGGVGVVWDL 237
Cdd:TIGR01934 111 --TIA--FGLRNV---TDIQKALREMYRVLKPGGRLVILEF 144
 
Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 92-249 9.99e-19

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 80.42  E-value: 9.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434  92 YSAVPLRYEMAQRMVGSVGDwSSVKTALDLGCGRGILLNAVATQlkktgsSGRVVGLDRS--MtttLSTLRtAHIEGVQE 169
Cdd:COG2226     1 FDRVAARYDGREALLAALGL-RPGARVLDLGCGTGRLALALAER------GARVTGVDISpeM---LELAR-ERAAEAGL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 170 YVTCREGDVRRLPFSDNYFDVVVSAVFLHTIgkeygqktveaaAERMRVLGEAVRVLKPGGVGVVWDLV--HVPEYVRRL 247
Cdd:COG2226    70 NVEFVVGDAEDLPFPDGSFDLVISSFVLHHL------------PDPERALAEIARVLKPGGRLVVVDFSppDLAELEELL 137


                  ..
gi 1789575434 248 QE 249
Cdd:COG2226   138 AE 139
PRK08317 PRK08317
hypothetical protein; Provisional
 117-236 3.64e-18

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 81.52  E-value: 3.64e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 117 TALDLGCGRGILLNAVAtqlKKTGSSGRVVGLDRSmtTTLSTLRTAHIEGVQEYVTCREGDVRRLPFSDNYFDVVVSavf 196
Cdd:PRK08317   22 RVLDVGCGPGNDARELA---RRVGPEGRVVGIDRS--EAMLALAKERAAGLGPNVEFVRGDADGLPFPDGSFDAVRS--- 93

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1789575434 197 lhtigkeygQKTVEAAAERMRVLGEAVRVLKPGGVGVVWD 236
Cdd:PRK08317   94 ---------DRVLQHLEDPARALAEIARVLRPGGRVVVLD 124
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 119-230 8.38e-18

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 76.83  E-value: 8.38e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 119 LDLGCGRGILLNAVATQLKktgssGRVVGLDRS--MtttLSTLRtAHIEGVQEYVTCREGDVRRLPFSDNYFDVVVSAVF 196
Cdd:pfam13649   2 LDLGCGTGRLTLALARRGG-----ARVTGVDLSpeM---LERAR-ERAAEAGLNVEFVQGDAEDLPFPDGSFDLVVSSGV 72

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1789575434 197 LHTIGKEygqktveaaaERMRVLGEAVRVLKPGG 230
Cdd:pfam13649  73 LHHLPDP----------DLEAALREIARVLKPGG 96
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 119-234 2.72e-17

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 75.39  E-value: 2.72e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 119 LDLGCGRGILLNAvatqLKKTGSsgRVVGLDRSMTTtlstLRTAHIEGVQEYVTCREGDVRRLPFSDNYFDVVVSAVFLH 198
Cdd:pfam08241   1 LDVGCGTGLLTEL----LARLGA--RVTGVDISPEM----LELAREKAPREGLTFVVGDAEDLPFPDNSFDLVLSSEVLH 70

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1789575434 199 TIgkeygqktveaaAERMRVLGEAVRVLKPGGVGVV 234
Cdd:pfam08241  71 HV------------EDPERALREIARVLKPGGILII 94
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 111-240 1.40e-14

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 71.34  E-value: 1.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 111 DWSSVK---TALDLGCGRGILLNAVAtqlKKTGSSGRVVGLDRSmtttLSTLRTA----HIEGVQEYVTCREGDVRRLPF 183
Cdd:PRK00216   45 KWLGVRpgdKVLDLACGTGDLAIALA---KAVGKTGEVVGLDFS----EGMLAVGreklRDLGLSGNVEFVQGDAEALPF 117

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1789575434 184 SDNYFDVVvsavflhTIGkeYGQKTVEaaaERMRVLGEAVRVLKPGGVGVVWDLVHV 240
Cdd:PRK00216  118 PDNSFDAV-------TIA--FGLRNVP---DIDKALREMYRVLKPGGRLVILEFSKP 162
arsM PRK11873
arsenite methyltransferase;
117-250 7.51e-14

arsenite methyltransferase;


Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 69.98  E-value: 7.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 117 TALDLGCGRGI--LLNAvatqlKKTGSSGRVVGLDrsMTTTLSTL-----RTAHIEGVqEYvtcREGDVRRLPFSDNYFD 189
Cdd:PRK11873   80 TVLDLGSGGGFdcFLAA-----RRVGPTGKVIGVD--MTPEMLAKaranaRKAGYTNV-EF---RLGEIEALPVADNSVD 148

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1789575434 190 VVVSAVFLHTigkeygqktveaAAERMRVLGEAVRVLKPGGVGVVWDLVH---VPEYVRRLQEL 250
Cdd:PRK11873  149 VIISNCVINL------------SPDKERVFKEAFRVLKPGGRFAISDVVLrgeLPEEIRNDAEL 200
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 117-238 1.33e-11

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 60.14  E-value: 1.33e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 117 TALDLGCGRGILLNAVATQLKKtgssgRVVGLDRSMTTtLSTLRTAHIEGVQEYVTCREGDVRRLPF-SDNYFDVVVSAV 195
Cdd:cd02440     1 RVLDLGCGTGALALALASGPGA-----RVTGVDISPVA-LELARKAAAALLADNVEVLKGDAEELPPeADESFDVIISDP 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1789575434 196 FLHTIgkeygqktveaAAERMRVLGEAVRVLKPGGVGVVWDLV 238
Cdd:cd02440    75 PLHHL-----------VEDLARFLEEARRLLKPGGVLVLTLVL 106
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 117-241 3.24e-11

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 60.33  E-value: 3.24e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 117 TALDLGCGRGILLNAVAtqlKKTGSsgRVVGLDRSMTTTLSTLRTAHIEGVQEYVTCREGDVRRLPFsDNYFDVVVSAVF 196
Cdd:COG2230    54 RVLDIGCGWGGLALYLA---RRYGV--RVTGVTLSPEQLEYARERAAEAGLADRVEVRLADYRDLPA-DGQFDAIVSIGM 127

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1789575434 197 LHTIGKEYgqktveaaaeRMRVLGEAVRVLKPGGVGvvwdLVHVP 241
Cdd:COG2230   128 FEHVGPEN----------YPAYFAKVARLLKPGGRL----LLHTP 158
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 116-234 4.43e-11

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 59.26  E-value: 4.43e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 116 KTALDLGCGRGILLNAvatqLKKTGSsgRVVGLDRSmtttLSTLRTAHIEGVQEYVTCREGDVRRLPFSDNYFDVVVS-A 194
Cdd:COG2227    26 GRVLDVGCGTGRLALA----LARRGA--DVTGVDIS----PEALEIARERAAELNVDFVQGDLEDLPLEDGSFDLVICsE 95

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1789575434 195 VFLHTigkeygqktveaaAERMRVLGEAVRVLKPGGVGVV 234
Cdd:COG2227    96 VLEHL-------------PDPAALLRELARLLKPGGLLLL 122
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
117-231 5.29e-10

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 55.60  E-value: 5.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 117 TALDLGCGRGILLNAVATQLKKtgssGRVVGLDRS--MtttLSTLRTAHiegvqEYVTCREGDVRRLPFSDNyFDVVVSA 194
Cdd:COG4106     4 RVLDLGCGTGRLTALLAERFPG----ARVTGVDLSpeM---LARARARL-----PNVRFVVADLRDLDPPEP-FDLVVSN 70

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1789575434 195 VFLHTIgkeygqktveaaAERMRVLGEAVRVLKPGGV 231
Cdd:COG4106    71 AALHWL------------PDHAALLARLAAALAPGGV 95
PLN02233 PLN02233
ubiquinone biosynthesis methyltransferase
 112-229 8.23e-10

ubiquinone biosynthesis methyltransferase


Pssm-ID: 177877 [Multi-domain]  Cd Length: 261  Bit Score: 57.98  E-value: 8.23e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 112 WSSVKTA---LDLGCGRGILLNAVAtqlKKTGSSGRVVGLDRSMTTTLSTLRTAHIEGVQEYVTCR--EGDVRRLPFSDN 186
Cdd:PLN02233   68 WSGAKMGdrvLDLCCGSGDLAFLLS---EKVGSDGKVMGLDFSSEQLAVAASRQELKAKSCYKNIEwiEGDATDLPFDDC 144

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1789575434 187 YFDVVvsavflhTIGkeYGQKTVeaaAERMRVLGEAVRVLKPG 229
Cdd:PLN02233  145 YFDAI-------TMG--YGLRNV---VDRLKAMQEMYRVLKPG 175
MenG_MenH_UbiE TIGR01934
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ...
 117-237 4.17e-09

ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273884 [Multi-domain]  Cd Length: 223  Bit Score: 55.73  E-value: 4.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 117 TALDLGCGRGILLNAVAtqlKKTGSSGRVVGLDRSmTTTLSTLRTAHIegVQEYVTCREGDVRRLPFSDNYFDVVvsavf 196
Cdd:TIGR01934  42 KVLDVACGTGDLAIELA---KSAPDRGKVTGVDFS-SEMLEVAKKKSE--LPLNIEFIQADAEALPFEDNSFDAV----- 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1789575434 197 lhTIGkeYGQKTVeaaAERMRVLGEAVRVLKPGGVGVVWDL 237
Cdd:TIGR01934 111 --TIA--FGLRNV---TDIQKALREMYRVLKPGGRLVILEF 144
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
100-247 1.18e-08

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 53.46  E-value: 1.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 100 EMAQRMVGSVGDwSSVKTALDLGCGRGILlnavATQLKKTGssGRVVGLDRS--MtttlstLRTAHIEGVqeYVTCREGD 177
Cdd:COG4976    33 LLAEELLARLPP-GPFGRVLDLGCGTGLL----GEALRPRG--YRLTGVDLSeeM------LAKAREKGV--YDRLLVAD 97

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1789575434 178 VRRLPFSDNYFDVVVSAVFLHTIGkeygqktveaaaERMRVLGEAVRVLKPGG--VGVVWDL------VHVPEYVRRL 247
Cdd:COG4976    98 LADLAEPDGRFDLIVAADVLTYLG------------DLAAVFAGVARALKPGGlfIFSVEDAdgsgryAHSLDYVRDL 163
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 117-234 1.57e-08

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 53.77  E-value: 1.57e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 117 TALDLGCGRGILLNAVATQLKktgssGRVVGLDRSmTTTLSTLRTAHIEGVQEYVTCREGDVRRL-PFSDNYFDVVVSAV 195
Cdd:COG0500    29 RVLDLGCGTGRNLLALAARFG-----GRVIGIDLS-PEAIALARARAAKAGLGNVEFLVADLAELdPLPAESFDLVVAFG 102

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1789575434 196 FLHTIGKEygqktveaaaERMRVLGEAVRVLKPGGVGVV 234
Cdd:COG0500   103 VLHHLPPE----------EREALLRELARALKPGGVLLL 131
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 117-250 5.42e-08

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 51.73  E-value: 5.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 117 TALDLGCGRGILlnavATQLKKTGSSGRVVGLDRSMTTTLSTLRTAHIEGVQEyVTCREGDVRRlPFSDNYFDVVVSAVF 196
Cdd:COG2813    52 RVLDLGCGYGVI----GLALAKRNPEARVTLVDVNARAVELARANAAANGLEN-VEVLWSDGLS-GVPDGSFDLILSNPP 125

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1789575434 197 LHTigkeyGQKTVEAAAERMrvLGEAVRVLKPGgvGVVWdLV---HVPeYVRRLQEL 250
Cdd:COG2813   126 FHA-----GRAVDKEVAHAL--IADAARHLRPG--GELW-LVanrHLP-YERKLEEL 171
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 100-231 7.18e-08

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 52.29  E-value: 7.18e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 100 EMAQRMVGSVGDWSSVKTA--LDLGCGRGILLNAvatqLKKTGSSGRVVGLDRSMtTTLSTLRTAhiegVQEYVTCREGD 177
Cdd:TIGR02072  18 EMAKRLLALLKEKGIFIPAsvLDIGCGTGYLTRA----LLKRFPQAEFIALDISA-GMLAQAKTK----LSENVQFICGD 88

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1789575434 178 VRRLPFSDNYFDVVVSAVFLHTIGKeygqktveaaaeRMRVLGEAVRVLKPGGV 231
Cdd:TIGR02072  89 AEKLPLEDSSFDLIVSNLALQWCDD------------LSQALSELARVLKPGGL 130
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 116-253 1.32e-07

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 50.11  E-value: 1.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 116 KTALDLGCGRGILLNAVAtqlKKTGSSGRVVGLDRSMtttlSTLRTAHIEGVQ---EYVTCREGDVRRLP--FSDNYFDV 190
Cdd:pfam13847   5 MRVLDLGCGTGHLSFELA---EELGPNAEVVGIDISE----EAIEKARENAQKlgfDNVEFEQGDIEELPelLEDDKFDV 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1789575434 191 VVSAVFLHTIgkeygqktveaaAERMRVLGEAVRVLKPGGVGVV---WDLVHVPEYVRRLQELRME 253
Cdd:pfam13847  78 VISNCVLNHI------------PDPDKVLQEILRVLKPGGRLIIsdpDSLAELPAHVKEDSTYYAG 131
Ubie_methyltran pfam01209
ubiE/COQ5 methyltransferase family;
117-240 6.00e-07

ubiE/COQ5 methyltransferase family;


Pssm-ID: 395966 [Multi-domain]  Cd Length: 228  Bit Score: 49.36  E-value: 6.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 117 TALDLGCGRGILLNAVAtqlKKTGSSGRVVGLDRSMTTTLSTLRTAHIEGVQ--EYVtcrEGDVRRLPFSDNYFDVVvsa 194
Cdd:pfam01209  45 KFLDVAGGTGDWTFGLS---DSAGSSGKVVGLDINENMLKEGEKKAKEEGKYniEFL---QGNAEELPFEDDSFDIV--- 115

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1789575434 195 vflhTIGkeYGQKTVeaaAERMRVLGEAVRVLKPGGVGVVWDLVHV 240
Cdd:pfam01209 116 ----TIS--FGLRNF---PDYLKVLKEAFRVLKPGGRVVCLEFSKP 152
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 116-231 1.21e-05

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 44.89  E-value: 1.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 116 KTALDLGCGRGILlnavATQLKKTGSSGRVVGLDRSMTTTLSTLRTAHIEGVqEYVTCREGDVRRlPFSDNYFDVVVSAV 195
Cdd:pfam05175  33 GKVLDLGCGAGVL----GAALAKESPDAELTMVDINARALESARENLAANGL-ENGEVVASDVYS-GVEDGKFDLIISNP 106

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1789575434 196 FLHTigkeyGQKTVEAAAERMrvLGEAVRVLKPGGV 231
Cdd:pfam05175 107 PFHA-----GLATTYNVAQRF--IADAKRHLRPGGE 135
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 119-231 7.05e-05

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 41.20  E-value: 7.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 119 LDLGCGRGILLNAVATQLkktgSSGRVVGLDRSmTTTLSTLRTAHIEGVQEYVTCREGDVRRLPFSD-NYFDVVVSAVFL 197
Cdd:pfam08242   1 LEIGCGTGTLLRALLEAL----PGLEYTGLDIS-PAALEAARERLAALGLLNAVRVELFQLDLGELDpGSFDVVVASNVL 75

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1789575434 198 HtigkeygqktveAAAERMRVLGEAVRVLKPGGV 231
Cdd:pfam08242  76 H------------HLADPRAVLRNIRRLLKPGGV 97
PRK14968 PRK14968
putative methyltransferase; Provisional
 116-261 1.78e-04

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 41.42  E-value: 1.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 116 KTALDLGCGRGIllnaVATQLKKTGssGRVVGLDRSMTTTLSTLRTAHIEGVQEY-VTCREGDVRRlPFSDNYFDVVV-S 193
Cdd:PRK14968   25 DRVLEVGTGSGI----VAIVAAKNG--KKVVGVDINPYAVECAKCNAKLNNIRNNgVEVIRSDLFE-PFRGDKFDVILfN 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 194 AVFLHT--------------IGKEYGQKTVEaaaermRVLGEAVRVLKPGGVG--VVWDLVHVPEYVRRLQELRME-EIR 256
Cdd:PRK14968   98 PPYLPTeeeeewddwlnyalSGGKDGREVID------RFLDEVGRYLKPGGRIllLQSSLTGEDEVLEYLEKLGFEaEVV 171


                  ....*
gi 1789575434 257 VSKRV 261
Cdd:PRK14968  172 AEEKF 176
PLN02244 PLN02244
tocopherol O-methyltransferase
 102-264 2.36e-04

tocopherol O-methyltransferase


Pssm-ID: 215135 [Multi-domain]  Cd Length: 340  Bit Score: 42.04  E-value: 2.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 102 AQ-RMVGSVGDWSSV--------KTALDLGCGRGillnavatqlkktGSSGRVVGLDRSMTT--TLSTLRTAHI------ 164
Cdd:PLN02244   97 AQiRMIEESLAWAGVpdddekrpKRIVDVGCGIG-------------GSSRYLARKYGANVKgiTLSPVQAARAnalaaa 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 165 EGVQEYVTCREGDVRRLPFSDNYFDVVVSAvflhtigkEYGqktvEAAAERMRVLGEAVRVLKPGG--VGVVW---DLVH 239
Cdd:PLN02244  164 QGLSDKVSFQVADALNQPFEDGQFDLVWSM--------ESG----EHMPDKRKFVQELARVAAPGGriIIVTWchrDLEP 231

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1789575434 240 ---------------------------VPEYVRRLQELRMEEIRV---SKRVTAF 264
Cdd:PLN02244  232 getslkpdeqklldkicaayylpawcsTSDYVKLAESLGLQDIKTedwSEHVAPF 286
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 110-193 6.04e-04

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 40.51  E-value: 6.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 110 GDWSSVK---TALDLGCGRGILLNAVATQLKKtgssGRVVGLDRSMTTTLSTLRTAHIEGVQEYVTCREGDVRRLP--FS 184
Cdd:COG4123    30 AAFAPVKkggRVLDLGTGTGVIALMLAQRSPG----ARITGVEIQPEAAELARRNVALNGLEDRITVIHGDLKEFAaeLP 105


                  ....*....
gi 1789575434 185 DNYFDVVVS 193
Cdd:COG4123   106 PGSFDLVVS 114
COG4627 COG4627
Predicted SAM-depedendent methyltransferase [General function prediction only];
176-231 1.13e-03

Predicted SAM-depedendent methyltransferase [General function prediction only];


Pssm-ID: 443666 [Multi-domain]  Cd Length: 161  Bit Score: 38.69  E-value: 1.13e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1789575434 176 GDVR-RLPFSDNYFDVVVSAVFLHTIGKEYGqktveaaaerMRVLGEAVRVLKPGGV 231
Cdd:COG4627    34 GDLTdPLPFPDNSVDAIYSSHVLEHLDYEEA----------PLALKECYRVLKPGGI 80
Trm11 COG1041
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ...
 90-262 1.31e-03

tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440663 [Multi-domain]  Cd Length: 172  Bit Score: 38.78  E-value: 1.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434  90 FFYSAVpLRYEMAQRMVGSVGDWSSvKTALDLGCGRG-ILLNAvatqlkktGSSG-RVVGLD------RSMTTTLSTLRT 161
Cdd:COG1041     4 FFYPGS-LDPRLARALVNLAGAKEG-DTVLDPFCGTGtILIEA--------GLLGrRVIGSDidpkmvEGARENLEHYGY 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 162 ahiegvqEYVTCREGDVRRLPFSDNYFDVVVS----AVFLHTIGKEYgQKTVEAAAErmrvlgEAVRVLKPGG-VGVVWD 236
Cdd:COG1041    74 -------EDADVIRGDARDLPLADESVDAIVTdppyGRSSKISGEEL-LELYEKALE------EAARVLKPGGrVVIVTP 139

                         170       180
                  ....*....|....*....|....*...
gi 1789575434 237 lVHVPEYVRR--LQELRMEEIRVSKRVT 262
Cdd:COG1041   140 -RDIDELLEEagFKVLERHEQRVHKSLT 166
PRK06922 PRK06922
class I SAM-dependent methyltransferase;
111-236 1.90e-03

class I SAM-dependent methyltransferase;


Pssm-ID: 180751 [Multi-domain]  Cd Length: 677  Bit Score: 39.47  E-value: 1.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 111 DWSSVKTALDLGCGRGILLNAVATQLKKTgssgRVVGLDRSMTTTLSTLRTAHIEGVQEYVtcREGDVRRLP--FSDNYF 188
Cdd:PRK06922  415 DYIKGDTIVDVGAGGGVMLDMIEEETEDK----RIYGIDISENVIDTLKKKKQNEGRSWNV--IKGDAINLSssFEKESV 488

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1789575434 189 DVVVSAVFLHTI-------GKEYGQKTVEAAaermrvLGEAVRVLKPGGVGVVWD 236
Cdd:PRK06922  489 DTIVYSSILHELfsyieyeGKKFNHEVIKKG------LQSAYEVLKPGGRIIIRD 537
PLN02490 PLN02490
MPBQ/MSBQ methyltransferase
 171-239 2.02e-03

MPBQ/MSBQ methyltransferase


Pssm-ID: 215270 [Multi-domain]  Cd Length: 340  Bit Score: 39.10  E-value: 2.02e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1789575434 171 VTCREGDVRRLPFSDNYFDVVVSAvflhtigkeygqKTVEAAAERMRVLGEAVRVLKPGGVGVVWDLVH 239
Cdd:PLN02490  162 CKIIEGDAEDLPFPTDYADRYVSA------------GSIEYWPDPQRGIKEAYRVLKIGGKACLIGPVH 218
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
116-193 2.72e-03

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 37.96  E-value: 2.72e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1789575434 116 KTALDLGCGRGILlnAVATQLKktgSSGRVVGLDRSmTTTLSTLRTAhIEGVQEYVTCREGDVRRLPFSDNyFDVVVS 193
Cdd:COG2263    47 KTVLDLGCGTGML--AIGAALL---GAKKVVGVDID-PEALEIAREN-AERLGVRVDFIRADVTRIPLGGS-VDTVVM 116
PLN02232 PLN02232
ubiquinone biosynthesis methyltransferase
 175-229 6.20e-03

ubiquinone biosynthesis methyltransferase


Pssm-ID: 165876  Cd Length: 160  Bit Score: 36.59  E-value: 6.20e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1789575434 175 EGDVRRLPFSDNYFDVVvsavflhTIGkeYGQKTVeaaAERMRVLGEAVRVLKPG 229
Cdd:PLN02232   32 EGDAIDLPFDDCEFDAV-------TMG--YGLRNV---VDRLRAMKEMYRVLKPG 74
prmA TIGR00406
ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an ...
 116-230 6.23e-03

ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an S-adenosyl-L-methionine-dependent methyltransferase required for the modification of ribosomal protein L11. This protein is found in bacteria and (with a probable transit peptide) in Arabidopsis. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273061  Cd Length: 288  Bit Score: 37.51  E-value: 6.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 116 KTALDLGCGRGILlnavATQLKKTGSSgRVVGLDRSMTTTLSTLRTAHIEGVQEYVTCREGDVRRLpfSDNYFDVVVSAV 195
Cdd:TIGR00406 161 KNVIDVGCGSGIL----SIAALKLGAA-KVVGIDIDPLAVESARKNAELNQVSDRLQVKLIYLEQP--IEGKADVIVANI 233

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1789575434 196 FLHTIgkeygqktveaaaerMRVLGEAVRVLKPGG 230
Cdd:TIGR00406 234 LAEVI---------------KELYPQFSRLVKPGG 253
YhdJ COG0863
DNA modification methylase [Replication, recombination and repair];
173-253 9.03e-03

DNA modification methylase [Replication, recombination and repair];


Pssm-ID: 440623  Cd Length: 236  Bit Score: 36.82  E-value: 9.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789575434 173 CREGdVRRLPfsDNYFDVVVsavflhT-----IGKEYGQKTVEAAAER---------MRVLGEAVRVLKPGGVGVVW-DL 237
Cdd:COG0863     7 CLEV-LKELP--DESVDLIV------TdppynLGKKYGLGRREIGNELsfeeyleflREWLAECYRVLKPGGSLYVNiGD 77

                          90
                  ....*....|....*.
gi 1789575434 238 VHVPEYVRRLQELRME 253
Cdd:COG0863    78 RYISRLIAALRDAGFK 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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