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Conserved domains on  [gi|1789572021|emb|CAA0402668|]
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unnamed protein product [Arabidopsis thaliana]

Protein Classification

alpha/beta hydrolase family protein( domain architecture ID 229394)

alpha/beta hydrolase family protein may catalyze the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Abhydrolase super family cl21494
alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, ...
 7-315 9.91e-109

alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, peroxidases, esterases, epoxide hydrolases and dehalogenases. The catalytic apparatus typically involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine, and often the mechanism involves a nucleophilic attack on a carbonyl carbon atom.


The actual alignment was detected with superfamily member PLN02298:

Pssm-ID: 473884 [Multi-domain]  Cd Length: 330  Bit Score: 319.80  E-value: 9.91e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021   7 SEANASSPFGSLSAAEFYSRHSVTHSSAYVTNPTGLKLFTQWWTPLNR-PPLGLIAVVHGFTGESSWFLQLTSVLFAKSG 85
Cdd:PLN02298    8 ATETEVHFWGETPEEEYYALKGIKGSKSFFTSPRGLSLFTRSWLPSSSsPPRALIFMVHGYGNDISWTFQSTAIFLAQMG 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  86 YLTCAIDHQGHGFSDGLTAHIPNINLIVDDCISFFDDFRKRHASSFLPAFLYSESLGGAIALYITLRQKHQWNGLILSGA 165
Cdd:PLN02298   88 FACFALDLEGHGRSEGLRAYVPNVDLVVEDCLSFFNSVKQREEFQGLPRFLYGESMGGAICLLIHLANPEGFDGAVLVAP 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 166 MCSISHKFKPPWPLQHLLTLAATLIPTWRVVPTrGSIAGVSFKEPWKRKLAYANPNRTVGKPRAATAYELVRVCEDLQNR 245
Cdd:PLN02298  168 MCKISDKIRPPWPIPQILTFVARFLPTLAIVPT-ADLLEKSVKVPAKKIIAKRNPMRYNGKPRLGTVVELLRVTDYLGKK 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1789572021 246 FEEVEVPLMIVHGRDDVVCDPASVEELYRRCSSRDKTIKIYPGMWHQLI-GESEENVDLVFGDVLDWIKTR 315
Cdd:PLN02298  247 LKDVSIPFIVLHGSADVVTDPDVSRALYEEAKSEDKTIKIYDGMMHSLLfGEPDENIEIVRRDILSWLNER 317
 
Name Accession Description Interval E-value
PLN02298 PLN02298
hydrolase, alpha/beta fold family protein
 7-315 9.91e-109

hydrolase, alpha/beta fold family protein


Pssm-ID: 165939 [Multi-domain]  Cd Length: 330  Bit Score: 319.80  E-value: 9.91e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021   7 SEANASSPFGSLSAAEFYSRHSVTHSSAYVTNPTGLKLFTQWWTPLNR-PPLGLIAVVHGFTGESSWFLQLTSVLFAKSG 85
Cdd:PLN02298    8 ATETEVHFWGETPEEEYYALKGIKGSKSFFTSPRGLSLFTRSWLPSSSsPPRALIFMVHGYGNDISWTFQSTAIFLAQMG 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  86 YLTCAIDHQGHGFSDGLTAHIPNINLIVDDCISFFDDFRKRHASSFLPAFLYSESLGGAIALYITLRQKHQWNGLILSGA 165
Cdd:PLN02298   88 FACFALDLEGHGRSEGLRAYVPNVDLVVEDCLSFFNSVKQREEFQGLPRFLYGESMGGAICLLIHLANPEGFDGAVLVAP 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 166 MCSISHKFKPPWPLQHLLTLAATLIPTWRVVPTrGSIAGVSFKEPWKRKLAYANPNRTVGKPRAATAYELVRVCEDLQNR 245
Cdd:PLN02298  168 MCKISDKIRPPWPIPQILTFVARFLPTLAIVPT-ADLLEKSVKVPAKKIIAKRNPMRYNGKPRLGTVVELLRVTDYLGKK 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1789572021 246 FEEVEVPLMIVHGRDDVVCDPASVEELYRRCSSRDKTIKIYPGMWHQLI-GESEENVDLVFGDVLDWIKTR 315
Cdd:PLN02298  247 LKDVSIPFIVLHGSADVVTDPDVSRALYEEAKSEDKTIKIYDGMMHSLLfGEPDENIEIVRRDILSWLNER 317
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 55-298 1.56e-75

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 231.72  E-value: 1.56e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  55 PPLGLIAVVHGFTGESSWFLQLTSVLfAKSGYLTCAIDHQGHGFSDGLTAHIPNINLIVDDCISFFDDFRKRHASsfLPA 134
Cdd:pfam12146   2 EPRAVVVLVHGLGEHSGRYAHLADAL-AAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEHPG--LPL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 135 FLYSESLGGAIALYITLRQKHQWNGLILSGAMCSISHKFkPPWPLQHLLTLAATLIPTWRVvPTRGSIAGVSfKEPWKRK 214
Cdd:pfam12146  79 FLLGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPYL-APPILKLLAKLLGKLFPRLRV-PNNLLPDSLS-RDPEVVA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 215 LAYANPNRTvGKPRAATAYELVRVCEDLQNRFEEVEVPLMIVHGRDDVVCDPASVEELYRRCSSRDKTIKIYPGMWHQLI 294
Cdd:pfam12146 156 AYAADPLVH-GGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELL 234


                  ....
gi 1789572021 295 GESE 298
Cdd:pfam12146 235 NEPD 238
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
30-313 2.98e-32

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 119.72  E-value: 2.98e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  30 THSSAYVTNPTGLKLFTQWWTPlNRPPLGLIAVVHGFtGESSWFLQLTSVLFAKSGYLTCAIDHQGHGFSDGLTAHIPNI 109
Cdd:COG2267     2 TRRLVTLPTRDGLRLRGRRWRP-AGSPRGTVVLVHGL-GEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 110 NLIVDDCISFFDDFRKRHAssfLPAFLYSESLGGAIALYITLRQKHQWNGLILSGamcsishkfkppwplqhlltlaatl 189
Cdd:COG2267    80 DDYVDDLRAALDALRARPG---LPVVLLGHSMGGLIALLYAARYPDRVAGLVLLA------------------------- 131

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 190 iPTWRVVPTRGsiagvsfkepwkrklayanpnrtvgkPRAATAYELvrvceDLQNRFEEVEVPLMIVHGRDDVVCDPASV 269
Cdd:COG2267   132 -PAYRADPLLG--------------------------PSARWLRAL-----RLAEALARIDVPVLVLHGGADRVVPPEAA 179

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1789572021 270 EELYRRCsSRDKTIKIYPGMWHQLIgeSEENVDLVFGDVLDWIK 313
Cdd:COG2267   180 RRLAARL-SPDVELVLLPGARHELL--NEPAREEVLAAILAWLE 220
PST-A TIGR01607
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ...
 38-313 7.40e-12

Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.


Pssm-ID: 162444 [Multi-domain]  Cd Length: 332  Bit Score: 65.19  E-value: 7.40e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  38 NPTGLKLFTQWWTPLNrpPLGLIAVVHGFTG------------------------------ESSWFLQltsvlFAKSGYL 87
Cdd:TIGR01607   4 NKDGLLLKTYSWIVKN--AIGIIVLIHGLKShlrlqflkinakivnndravlidtdnyyiyKDSWIEN-----FNKNGYS 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  88 TCAIDHQGHGFSDG---LTAHIPNINLIVDDCISF---------------FDDFRKRHASSF---LPAFLYSESLGGAIA 146
Cdd:TIGR01607  77 VYGLDLQGHGESDGlqnLRGHINCFDDLVYDVIQYmnrindsiilenetkSDDESYDIVNTKenrLPMYIIGLSMGGNIA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 147 L-YITLRQKHQWN-------GLILSGAMCSI-------SHKFKppWPLQHLLTLAATLIPTWRVVPtrgsiaGVSF-KEP 210
Cdd:TIGR01607 157 LrLLELLGKSNENndklnikGCISLSGMISIksvgsddSFKFK--YFYLPVMNFMSRVFPTFRISK------KIRYeKSP 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 211 WKRKLAYANPNRTVGKPRAATAYELVRVCEDLQNRFEEV--EVPLMIVHGRDDVVCDPASVEELYRRCSSRDKTIKIYPG 288
Cdd:TIGR01607 229 YVNDIIKFDKFRYDGGITFNLASELIKATDTLDCDIDYIpkDIPILFIHSKGDCVCSYEGTVSFYNKLSISNKELHTLED 308

                         330       340
                  ....*....|....*....|....*.
gi 1789572021 289 MWHQLIGE-SEENvdlVFGDVLDWIK 313
Cdd:TIGR01607 309 MDHVITIEpGNEE---VLKKIIEWIS 331
 
Name Accession Description Interval E-value
PLN02298 PLN02298
hydrolase, alpha/beta fold family protein
 7-315 9.91e-109

hydrolase, alpha/beta fold family protein


Pssm-ID: 165939 [Multi-domain]  Cd Length: 330  Bit Score: 319.80  E-value: 9.91e-109
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021   7 SEANASSPFGSLSAAEFYSRHSVTHSSAYVTNPTGLKLFTQWWTPLNR-PPLGLIAVVHGFTGESSWFLQLTSVLFAKSG 85
Cdd:PLN02298    8 ATETEVHFWGETPEEEYYALKGIKGSKSFFTSPRGLSLFTRSWLPSSSsPPRALIFMVHGYGNDISWTFQSTAIFLAQMG 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  86 YLTCAIDHQGHGFSDGLTAHIPNINLIVDDCISFFDDFRKRHASSFLPAFLYSESLGGAIALYITLRQKHQWNGLILSGA 165
Cdd:PLN02298   88 FACFALDLEGHGRSEGLRAYVPNVDLVVEDCLSFFNSVKQREEFQGLPRFLYGESMGGAICLLIHLANPEGFDGAVLVAP 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 166 MCSISHKFKPPWPLQHLLTLAATLIPTWRVVPTrGSIAGVSFKEPWKRKLAYANPNRTVGKPRAATAYELVRVCEDLQNR 245
Cdd:PLN02298  168 MCKISDKIRPPWPIPQILTFVARFLPTLAIVPT-ADLLEKSVKVPAKKIIAKRNPMRYNGKPRLGTVVELLRVTDYLGKK 246

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1789572021 246 FEEVEVPLMIVHGRDDVVCDPASVEELYRRCSSRDKTIKIYPGMWHQLI-GESEENVDLVFGDVLDWIKTR 315
Cdd:PLN02298  247 LKDVSIPFIVLHGSADVVTDPDVSRALYEEAKSEDKTIKIYDGMMHSLLfGEPDENIEIVRRDILSWLNER 317
PLN02385 PLN02385
hydrolase; alpha/beta fold family protein
 35-316 1.11e-77

hydrolase; alpha/beta fold family protein


Pssm-ID: 215216 [Multi-domain]  Cd Length: 349  Bit Score: 241.20  E-value: 1.11e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  35 YVTNPTGLKLFTQWWTPLNRPPLGLIAVVHGFTGESSWFLQLTSVLFAKSGYLTCAIDHQGHGFSDGLTAHIPNINLIVD 114
Cdd:PLN02385   65 YEVNSRGVEIFSKSWLPENSRPKAAVCFCHGYGDTCTFFFEGIARKIASSGYGVFAMDYPGFGLSEGLHGYIPSFDDLVD 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 115 DCISFFDDFRKRHASSFLPAFLYSESLGGAIALYITLRQKHQWNGLILSGAMCSISHKFKPPWPLQHLLTLAATLIPTWR 194
Cdd:PLN02385  145 DVIEHYSKIKGNPEFRGLPSFLFGQSMGGAVALKVHLKQPNAWDGAILVAPMCKIADDVVPPPLVLQILILLANLLPKAK 224

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 195 VVPTRgSIAGVSFKEPWKRKLAYANPNRTVGKPRAATAYELVRVCEDLQNRFEEVEVPLMIVHGRDDVVCDPASVEELYR 274
Cdd:PLN02385  225 LVPQK-DLAELAFRDLKKRKMAEYNVIAYKDKPRLRTAVELLRTTQEIEMQLEEVSLPLLILHGEADKVTDPSVSKFLYE 303

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1789572021 275 RCSSRDKTIKIYPGMWHQLI-GESEENVDLVFGDVLDWIKTRS 316
Cdd:PLN02385  304 KASSSDKKLKLYEDAYHSILeGEPDEMIFQVLDDIISWLDSHS 346
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 55-298 1.56e-75

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 231.72  E-value: 1.56e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  55 PPLGLIAVVHGFTGESSWFLQLTSVLfAKSGYLTCAIDHQGHGFSDGLTAHIPNINLIVDDCISFFDDFRKRHASsfLPA 134
Cdd:pfam12146   2 EPRAVVVLVHGLGEHSGRYAHLADAL-AAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEHPG--LPL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 135 FLYSESLGGAIALYITLRQKHQWNGLILSGAMCSISHKFkPPWPLQHLLTLAATLIPTWRVvPTRGSIAGVSfKEPWKRK 214
Cdd:pfam12146  79 FLLGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPYL-APPILKLLAKLLGKLFPRLRV-PNNLLPDSLS-RDPEVVA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 215 LAYANPNRTvGKPRAATAYELVRVCEDLQNRFEEVEVPLMIVHGRDDVVCDPASVEELYRRCSSRDKTIKIYPGMWHQLI 294
Cdd:pfam12146 156 AYAADPLVH-GGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELL 234


                  ....
gi 1789572021 295 GESE 298
Cdd:pfam12146 235 NEPD 238
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
30-313 2.98e-32

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 119.72  E-value: 2.98e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  30 THSSAYVTNPTGLKLFTQWWTPlNRPPLGLIAVVHGFtGESSWFLQLTSVLFAKSGYLTCAIDHQGHGFSDGLTAHIPNI 109
Cdd:COG2267     2 TRRLVTLPTRDGLRLRGRRWRP-AGSPRGTVVLVHGL-GEHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 110 NLIVDDCISFFDDFRKRHAssfLPAFLYSESLGGAIALYITLRQKHQWNGLILSGamcsishkfkppwplqhlltlaatl 189
Cdd:COG2267    80 DDYVDDLRAALDALRARPG---LPVVLLGHSMGGLIALLYAARYPDRVAGLVLLA------------------------- 131

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 190 iPTWRVVPTRGsiagvsfkepwkrklayanpnrtvgkPRAATAYELvrvceDLQNRFEEVEVPLMIVHGRDDVVCDPASV 269
Cdd:COG2267   132 -PAYRADPLLG--------------------------PSARWLRAL-----RLAEALARIDVPVLVLHGGADRVVPPEAA 179

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 1789572021 270 EELYRRCsSRDKTIKIYPGMWHQLIgeSEENVDLVFGDVLDWIK 313
Cdd:COG2267   180 RRLAARL-SPDVELVLLPGARHELL--NEPAREEVLAAILAWLE 220
PLN02652 PLN02652
hydrolase; alpha/beta fold family protein
 44-315 1.02e-30

hydrolase; alpha/beta fold family protein


Pssm-ID: 215352 [Multi-domain]  Cd Length: 395  Bit Score: 119.61  E-value: 1.02e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  44 LFTQWWTPLNRPPLGLIAVVHGFTGESSWFLQLTSVLFAkSGYLTCAIDHQGHGFSDGLTAHIPNINLIVDDCISFFDDF 123
Cdd:PLN02652  123 LFCRSWAPAAGEMRGILIIIHGLNEHSGRYLHFAKQLTS-CGFGVYAMDWIGHGGSDGLHGYVPSLDYVVEDTEAFLEKI 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 124 RKRHASsfLPAFLYSESLGGAI----ALYITLRQKHQwnGLILSgamcSISHKFKPPWPLqhlltlAATLIPTWRVVPTR 199
Cdd:PLN02652  202 RSENPG--VPCFLFGHSTGGAVvlkaASYPSIEDKLE--GIVLT----SPALRVKPAHPI------VGAVAPIFSLVAPR 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 200 GSIAG-------VSfKEPWKRKLAYANPNRTVGKPRAATAYELVRVCEDLQNRFEEVEVPLMIVHGRDDVVCDPASVEEL 272
Cdd:PLN02652  268 FQFKGankrgipVS-RDPAALLAKYSDPLVYTGPIRVRTGHEILRISSYLTRNFKSVTVPFMVLHGTADRVTDPLASQDL 346

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1789572021 273 YRRCSSRDKTIKIYPGMWHQLIGESEEnvDLVFGDVLDWIKTR 315
Cdd:PLN02652  347 YNEAASRHKDIKLYDGFLHDLLFEPER--EEVGRDIIDWMEKR 387
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
63-317 5.13e-20

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 87.30  E-value: 5.13e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  63 VHGFTGeSSWFLQLTSVLFAKSGYLTCAIDHQGHGFSdglTAHIPNINliVDDCISF----FDDFRKRHAssflPAFLYS 138
Cdd:COG1647    21 LHGFTG-SPAEMRPLAEALAKAGYTVYAPRLPGHGTS---PEDLLKTT--WEDWLEDveeaYEILKAGYD----KVIVIG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 139 ESLGGAIALYITLRQKHQwNGLILsgamcsISHKFKPPWPLQHLLTLAATLIPTWRVVptrgsiaGVSFKEPWKRKLAYa 218
Cdd:COG1647    91 LSMGGLLALLLAARYPDV-AGLVL------LSPALKIDDPSAPLLPLLKYLARSLRGI-------GSDIEDPEVAEYAY- 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 219 npNRTvgkPRAAtAYELVRVCEDLQNRFEEVEVPLMIVHGRDDVVCDPASVEELYRRCSSRDKTIKIYPGMWHQLIgeSE 298
Cdd:COG1647   156 --DRT---PLRA-LAELQRLIREVRRDLPKITAPTLIIQSRKDEVVPPESARYIYERLGSPDKELVWLEDSGHVIT--LD 227

                         250
                  ....*....|....*....
gi 1789572021 299 ENVDLVFGDVLDWIKTRSE 317
Cdd:COG1647   228 KDREEVAEEILDFLERLAA 246
PHA02857 PHA02857
monoglyceride lipase; Provisional
 35-318 8.12e-20

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 87.63  E-value: 8.12e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  35 YVTNPTGLKLFTQWWTPLNRPPlGLIAVVHGfTGESSWFLQLTSVLFAKSGYLTCAIDHQGHGFSDGLTAHIPNINLIVD 114
Cdd:PHA02857    4 CMFNLDNDYIYCKYWKPITYPK-ALVFISHG-AGEHSGRYEELAENISSLGILVFSHDHIGHGRSNGEKMMIDDFGVYVR 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 115 DCISFFDDFRKRHASsfLPAFLYSESLGGAIALYITLRQKHQWNGLILSGAMCSISHkfkppwpLQHLLTLAATLIPTWR 194
Cdd:PHA02857   82 DVVQHVVTIKSTYPG--VPVFLLGHSMGATISILAAYKNPNLFTAMILMSPLVNAEA-------VPRLNLLAAKLMGIFY 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 195 VVPTRGSIAGVSFKEPWKRKLAY-ANPNRTVGKPRAATAYELVRVCEDLQNRFEEVEVPLMIVHGRDDVVCDPASVEELY 273
Cdd:PHA02857  153 PNKIVGKLCPESVSRDMDEVYKYqYDPLVNHEKIKAGFASQVLKATNKVRKIIPKIKTPILILQGTNNEISDVSGAYYFM 232

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1789572021 274 RRCSSrDKTIKIYPGMWHQLIGESEENVDLVFGDVLDWIKTRSEI 318
Cdd:PHA02857  233 QHANC-NREIKIYEGAKHHLHKETDEVKKSVMKEIETWIFNRVKV 276
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
36-313 2.16e-17

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 79.68  E-value: 2.16e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  36 VTNPTGLKLFTQWWTPLNRPPLGLIAVVHGFTGESSWFLQLTSVLFAKSGYLTCAIDHQGHGFSDGLTAHIPninliVDD 115
Cdd:COG1506     2 FKSADGTTLPGWLYLPADGKKYPVVVYVHGGPGSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGDWGGDE-----VDD 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 116 CISFFDDFRKRhasSFLPA---FLYSESLGGAIALYITLRQKHQWNGLILSGAMCSISHkfkppwplqhlltlaatlipt 192
Cdd:COG1506    77 VLAAIDYLAAR---PYVDPdriGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRS--------------------- 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 193 wrVVPTRGSIAGVSFKEPWKRKLAYANPnrtvgkpraatayelvrvceDLQNRFEEVEVPLMIVHGRDDVVCDPASVEEL 272
Cdd:COG1506   133 --YYGTTREYTERLMGGPWEDPEAYAAR--------------------SPLAYADKLKTPLLLIHGEADDRVPPEQAERL 190

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1789572021 273 YRRCSSR--DKTIKIYPGMWHqliGESEENVDLVFGDVLDWIK 313
Cdd:COG1506   191 YEALKKAgkPVELLVYPGEGH---GFSGAGAPDYLERILDFLD 230
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 23-314 1.75e-15

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 74.95  E-value: 1.75e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  23 FYSRHSVTHSSAYVTNPTGLKLFTQWWTPLNR-PPLGLIAVVHGFTGESSWFLQLTSvLFAKSGYLTCAIDHQGHGFSDG 101
Cdd:COG1073     2 FPPSDKVNKEDVTFKSRDGIKLAGDLYLPAGAsKKYPAVVVAHGNGGVKEQRALYAQ-RLAELGFNVLAFDYRGYGESEG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 102 LTAH--IPNINlivdDCISFFDDFRKRhasSFLPA---FLYSESLGGAIALYITLRQKhQWNGLILSGAMCSISHKFKpp 176
Cdd:COG1073    81 EPREegSPERR----DARAAVDYLRTL---PGVDPeriGLLGISLGGGYALNAAATDP-RVKAVILDSPFTSLEDLAA-- 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 177 wplQHLLTLAATLIPTWRVVPTrgsiagvsfkepwkrklayanpnrtvgkpraATAYELVRVCEDLQNRFEEVEVPLMIV 256
Cdd:COG1073   151 ---QRAKEARGAYLPGVPYLPN-------------------------------VRLASLLNDEFDPLAKIEKISRPLLFI 196

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1789572021 257 HGRDDVVCDPASVEELYRRCSSrDKTIKIYPGMWH-QLIgesEENVDLVFGDVLDWIKT 314
Cdd:COG1073   197 HGEKDEAVPFYMSEDLYEAAAE-PKELLIVPGAGHvDLY---DRPEEEYFDKLAEFFKK 251
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 63-313 3.10e-12

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 65.02  E-value: 3.10e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  63 VHGFTGESSWFLQLTSVLFAksGYLTCAIDHQGHGFSDGLTAHIpNINLIVDDCISFFDDFRKRhassflPAFLYSESLG 142
Cdd:COG0596    29 LHGLPGSSYEWRPLIPALAA--GYRVIAPDLRGHGRSDKPAGGY-TLDDLADDLAALLDALGLE------RVVLVGHSMG 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 143 GAIALYITLRQKHQWNGLILSGAMcsishkfkppwplqhlltlaatliptwrvvptrgsiagvsfkepwkRKLAYANPNR 222
Cdd:COG0596   100 GMVALELAARHPERVAGLVLVDEV----------------------------------------------LAALAEPLRR 133

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 223 TVGKPRAATAYELVRVCEDLQNRFEEVEVPLMIVHGRDDVVCDPASVEELYRRCssRDKTIKIYPGMWHQLIgesEENVD 302
Cdd:COG0596   134 PGLAPEALAALLRALARTDLRERLARITVPTLVIWGEKDPIVPPALARRLAELL--PNAELVVLPGAGHFPP---LEQPE 208

                         250
                  ....*....|.
gi 1789572021 303 LVFGDVLDWIK 313
Cdd:COG0596   209 AFAAALRDFLA 219
PST-A TIGR01607
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ...
 38-313 7.40e-12

Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.


Pssm-ID: 162444 [Multi-domain]  Cd Length: 332  Bit Score: 65.19  E-value: 7.40e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  38 NPTGLKLFTQWWTPLNrpPLGLIAVVHGFTG------------------------------ESSWFLQltsvlFAKSGYL 87
Cdd:TIGR01607   4 NKDGLLLKTYSWIVKN--AIGIIVLIHGLKShlrlqflkinakivnndravlidtdnyyiyKDSWIEN-----FNKNGYS 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  88 TCAIDHQGHGFSDG---LTAHIPNINLIVDDCISF---------------FDDFRKRHASSF---LPAFLYSESLGGAIA 146
Cdd:TIGR01607  77 VYGLDLQGHGESDGlqnLRGHINCFDDLVYDVIQYmnrindsiilenetkSDDESYDIVNTKenrLPMYIIGLSMGGNIA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 147 L-YITLRQKHQWN-------GLILSGAMCSI-------SHKFKppWPLQHLLTLAATLIPTWRVVPtrgsiaGVSF-KEP 210
Cdd:TIGR01607 157 LrLLELLGKSNENndklnikGCISLSGMISIksvgsddSFKFK--YFYLPVMNFMSRVFPTFRISK------KIRYeKSP 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 211 WKRKLAYANPNRTVGKPRAATAYELVRVCEDLQNRFEEV--EVPLMIVHGRDDVVCDPASVEELYRRCSSRDKTIKIYPG 288
Cdd:TIGR01607 229 YVNDIIKFDKFRYDGGITFNLASELIKATDTLDCDIDYIpkDIPILFIHSKGDCVCSYEGTVSFYNKLSISNKELHTLED 308

                         330       340
                  ....*....|....*....|....*.
gi 1789572021 289 MWHQLIGE-SEENvdlVFGDVLDWIK 313
Cdd:TIGR01607 309 MDHVITIEpGNEE---VLKKIIEWIS 331
PRK10749 PRK10749
lysophospholipase L2; Provisional
 84-279 6.84e-07

lysophospholipase L2; Provisional


Pssm-ID: 182697  Cd Length: 330  Bit Score: 50.00  E-value: 6.84e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  84 SGYLTCAIDHQGHGFS-----DGLTAHIPNINLIVDDCISFFD------DFRKRhassflpaFLYSESLGGAIALYITLR 152
Cdd:PRK10749   80 LGYDVLIIDHRGQGRSgrlldDPHRGHVERFNDYVDDLAAFWQqeiqpgPYRKR--------YALAHSMGGAILTLFLQR 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 153 QKHQWNGLILSGAMCSISHKFkPPWPLQHLLTLA----------ATLIPTWRVVPTRGSIAGVSfKEPWKRKLA-YAN-P 220
Cdd:PRK10749  152 HPGVFDAIALCAPMFGIVLPL-PSWMARRILNWAeghprirdgyAIGTGRWRPLPFAINVLTHS-RERYRRNLRfYADdP 229

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1789572021 221 NRTVGKPRAATAYELVRVCEDLQNRFEEVEVPLMIVHGRDDVVCDPASVEelyRRCSSR 279
Cdd:PRK10749  230 ELRVGGPTYHWVRESILAGEQVLAGAGDITTPLLLLQAEEERVVDNRMHD---RFCEAR 285
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
36-291 4.46e-06

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 46.88  E-value: 4.46e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  36 VTNPTGLKLFTQWWTPLNRPPLGLIAVVHGFTGESSWFLQLTSVLfAKSGYLTCAIDHQGHG----FSDGLTAHIP--NI 109
Cdd:COG0412     8 IPTPDGVTLPGYLARPAGGGPRPGVVVLHEIFGLNPHIRDVARRL-AAAGYVVLAPDLYGRGgpgdDPDEARALMGalDP 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 110 NLIVDDCISFFDDFRKRHASSFLPAFLYSESLGGAIALyitlrqkhqwnglilsgamcsishkfkppwplqhlltLAATL 189
Cdd:COG0412    87 ELLAADLRAALDWLKAQPEVDAGRVGVVGFCFGGGLAL-------------------------------------LAAAR 129

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 190 IPTWRvvptrgsiAGVSFkepwkrklaYANPNRTVGKPRAATayelvrvcedlqnrfeeVEVPLMIVHGRDDVVCDPASV 269
Cdd:COG0412   130 GPDLA--------AAVSF---------YGGLPADDLLDLAAR-----------------IKAPVLLLYGEKDPLVPPEQV 175

                         250       260
                  ....*....|....*....|....
gi 1789572021 270 EELYRRCSSR--DKTIKIYPGMWH 291
Cdd:COG0412   176 AALEAALAAAgvDVELHVYPGAGH 199
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 62-278 1.60e-04

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 42.49  E-value: 1.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021  62 VVHGFTGESSWFLQLTSVLfAKSGYLTCAIDHQGHGFSDgltAHIPNINLIVDDCISFFDDFRKrhASSFLPAFLYSESL 141
Cdd:pfam00561   5 LLHGLPGSSDLWRKLAPAL-ARDGFRVIALDLRGFGKSS---RPKAQDDYRTDDLAEDLEYILE--ALGLEKVNLVGHSM 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789572021 142 GGAIALYITLRQKHQWNGLILSGAMCSISH--------KFKPPW----PLQHLLTLAATLIPTWRVVPTRGSIAGVSFKE 209
Cdd:pfam00561  79 GGLIALAYAAKYPDRVKALVLLGALDPPHEldeadrfiLALFPGffdgFVADFAPNPLGRLVAKLLALLLLRLRLLKALP 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1789572021 210 PWKRKLAYANPNRTVGKPRAATAYELVRVCEDLQNRFEEVEVPLMIVHGRDDVVCDPASVEELYRRCSS 278
Cdd:pfam00561 159 LLNKRFPSGDYALAKSLVTGALLFIETWSTELRAKFLGRLDEPTLIIWGDQDPLVPPQALEKLAQLFPN 227
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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