|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
139-638 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 772.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 139 RPSTIREVKASHIGQLVRISGIVTRCSDVKPLMAVAVYTCEDCGHEIYQEVTSRVFMPLFKCPSSRCRLNSKagNPILQL 218
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP--FSLNHE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 219 RaSKFLKFQEAKMQELAEHVPKGHIPRSMTVHLRGELTRKVSPGDVVEFSGIFLPIPYtGFKALRAGLVAD--TYLEATS 296
Cdd:smart00350 79 R-STFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPY-GFKLNTVKGLPVfaTYIEANH 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 297 VTH--FKKKYEEYEFQ-----KDEEEQIARLAEDGDIYNKLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGD 369
Cdd:smart00350 157 VRKldYKRSFEDSSFSvqslsDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 370 VHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESD 449
Cdd:smart00350 237 INILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 450 RTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWGRYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELA 529
Cdd:smart00350 317 RTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELA 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 530 KHVLHVHQT-EESPALGFE-PLEPNILRAYISAAR-RLSPYVPAELEEYIATAYSSIRQEEAKSNT-PHSYTTVRTLLSI 605
Cdd:smart00350 397 KHVVDLHRYsHPEEDEAFEpPLSQEKLRKYIAYAReKIKPKLSEEAADKLVKAYVDLRKEDSQTESrSSIPITVRQLESI 476
|
490 500 510
....*....|....*....|....*....|...
gi 1789577082 606 LRISAALARLRFSESVAQSDVDEALRLMQMSKI 638
Cdd:smart00350 477 IRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
329-636 |
0e+00 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 587.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 329 KLSRSLAPEIYGHEDIKKALLLLLVGAPHRQlKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVG 408
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 409 LTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWG 488
Cdd:cd17758 80 LTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 489 RYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVHQTEESPALGFEPLEPNILRAYISAARRLSPYV 568
Cdd:cd17758 160 RYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDFEPLDPKLLRAYIALAKRKRPTV 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1789577082 569 PAELEEYIATAYSSIRQEEAKSNtPHSYTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQMS 636
Cdd:cd17758 240 PPALADYIVQAYVEMRQEAKRSK-DFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
14-669 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 556.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 14 KGFLENFadangrsKYMEILQEVSNR--KIRAIQVDLDDLFNYkdeSEEFLGRLTENTRRYVSIFSAAVDELLPEPTEaf 91
Cdd:COG1241 10 EEFLRRY-------KYRDEILELAQEypEKRSLVVDYNDLYSF---DPDLADDLLENPDEVLEAAEEALREIDLEPYD-- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 92 pDDDHDIlmtqraddgtdNPDVSDPHQQIPseikryyevyfkapskgrpstIREVKASHIGQLVRISGIVTRCSDVKPLM 171
Cdd:COG1241 78 -VSLGDA-----------HVRITNLPETVP---------------------IRDIRSDHIGKLISVEGIVRKATEVKPKI 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 172 AVAVYTCEDCGHEIYQEVTSRVFMPLFKCPSsrCrlnSKAGNPILQLRASKFLKFQEAKMQELAEHVPKGHIPRSMTVHL 251
Cdd:COG1241 125 TEAAFECPRCGTETYVPQTGEKLQEPHECPG--C---GRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVIL 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 252 RGELTRKVSPGDVVEFSGIFLPIPYTGFKALRAglVADTYLEATSVTHFKKKYEEYEFQKDEEEQIARLAEDGDIYNKLS 331
Cdd:COG1241 200 EDDLVGEVRPGDRVTVTGILRIEQRTSGRGKST--IFDLYLEANSIEVEEKEFEEIEITEEDEEKIKELSKDPDIYEKII 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 332 RSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTA 411
Cdd:COG1241 278 ASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTA 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 412 AVMRDQV-TNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWGRY 490
Cdd:COG1241 358 AAVRDDFgTGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRF 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 491 DLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVHQTEESPALGFE--------PLEPNILRAYISAAR 562
Cdd:COG1241 438 DPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVHRAGELLEQEIEeeteevkpEIDPDLLRKYIAYAR 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 563 R-LSPYVPAELEEYIATAYSSIRQEEAKSNTPHSyTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQmskISLy 641
Cdd:COG1241 518 RnVFPVLTEEAKDLIEDFYVDMRKKGEDEDSPVP-ITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVD---SCL- 592
|
650 660
....*....|....*....|....*...
gi 1789577082 642 addrQKAGLDAISDTYSIIRDEAARSKK 669
Cdd:COG1241 593 ----KDVGVDPETGKFDIDVIETGTSKS 616
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
14-634 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 540.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 14 KGFLENFADANGRSKYMEILQEVSNRKIRAIQVDLDDLFNYkdeSEEFLGRLTENTRRYVSIFSAAVDELLPEPTEAFPD 93
Cdd:NF040949 6 KEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMF---DPELADLLIEKPDEVLPAASKALKEIVEEEDPEYAE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 94 DDHDIlmtqraddgtdNPDVSDPHQQIPseikryyevyfkapskgrpstIREVKASHIGQLVRISGIVTRCSDVKPLMAV 173
Cdd:NF040949 83 EVAKF-----------HVRFRNLPRTVP---------------------LRDLRSEYIGKLIAVEGIVTRTTPVKPRIVK 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 174 AVYTCEDCGHEIY-----QEVTSRVFMPLfKCPssRCrlnSKAGNPILQLRASKFLKFQEAKMQELAEHVPKGHIPRSMT 248
Cdd:NF040949 131 AVFRCRDCGCEFEwpeeeEESYEIVEPPT-VCP--VC---GKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIE 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 249 VHLRGELTRKVSPGDVVEFSGIFLPIPYTGFKALRAGLVaDTYLEATSVTHFKKKYEEYEFQKDEEEQIARLAEDGDIYN 328
Cdd:NF040949 205 VVLEDDLVDTARPGDRVTVTGILRIKPDSSLKKGSRPIF-KNYIEANHIEVSQKELEEVEITEEDEEKILELAKDPWIRE 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 329 KLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVG 408
Cdd:NF040949 284 KIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAG 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 409 LTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWG 488
Cdd:NF040949 364 LTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFG 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 489 RYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVHQTEESpalgFEP-LEPNILRAYISAARR---- 563
Cdd:NF040949 444 RYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDVHSGKEK----VKPeIDPDLLKKYIAYARKyvrp 519
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1789577082 564 -LSPYVPAELEEYiataYSSIRQEEAKSNTPHS--YTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQ 634
Cdd:NF040949 520 kLTEEAKKLIEDF----YVEMRKSSKSSEDPDSpiPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLML 589
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
313-536 |
3.76e-145 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 422.71 E-value: 3.76e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 313 EEEQIARLAEDGDIYNKLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINV 392
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 393 APRGVYTTGKGSSGVGLTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTS 472
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1789577082 473 LNARTAVLAAANPAWGRYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVH 536
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
142-636 |
1.79e-89 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 299.60 E-value: 1.79e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 142 TIREVKASHIGQLVRISGIVTRCSDVKPLMAVAVYTC-----------EDCGHEIYQEVTS-RVFMPL----------FK 199
Cdd:PTZ00111 217 CVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCrgqkkiglndyQPCTCEHYEYVIQgEVNEPLlcnecnskytFE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 200 CPSSRCRLNSKAGNPILQLRASKFLKFQEAKMQELAEHVPKGHI----PRSMTVHLRGELTRKVSPGDVVEFSGIFLPIP 275
Cdd:PTZ00111 297 LNHNMCVYSTKKIVKLLQSNSSLNNPDKDGLDNSVDNSGLNGEIymkdNEVINLNLYDDLIDSVKTGDRVTVVGILKVTP 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 276 -------------YTGFKALRAGLVADTYLEATSVTHFKKKYEEYEFQKDEEEQIARLAEDGDIYNKLSRSLAPEIYGHE 342
Cdd:PTZ00111 377 irtsttrrtlkslYTYFVNVIHVKVINSTNANQPEKGLKYLGNENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARN 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 343 DIKKALLLLLVGAPHRQLKDGM---------KIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTAAV 413
Cdd:PTZ00111 457 NVKIGLLCQLFSGNKNSSDFNKspdacykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASI 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 414 -MRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWGRYDL 492
Cdd:PTZ00111 537 kFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNK 616
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 493 RRTPAENINLPPALLSRFDLLWLILDRADMDSD----LELAKHVLHVHQTEES--------------------PALGFEP 548
Cdd:PTZ00111 617 NKAVIENINISPSLFTRFDLIYLVLDHIDQDTDqlisLSIAKDFLLPHMTGSGndedtydrsntmhvedeslrSEKDYNK 696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 549 LEPNILRAYISAAR-RLSPYVPAELEEYIATAYSSIRQEE----------------------AKSNTPHSYTTVRTLLSI 605
Cdd:PTZ00111 697 NDLDMLRMYIKFSKlHCFPKLSDEAKKVITREYVKMRQGNfqtsnldelehaqedddddlyyQSSGTRMIYVSSRMISSI 776
|
570 580 590
....*....|....*....|....*....|.
gi 1789577082 606 LRISAALARLRFSESVAQSDVDEALRLMQMS 636
Cdd:PTZ00111 777 IRISVSLARMRLSTVVTPADALQAVQIVKSS 807
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
16-96 |
3.46e-11 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 60.00 E-value: 3.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 16 FLENF-ADANGRSKYMEILQEVSNRKIRAIQVDLDDLFNYkdeSEEFLGRLTENTRRYVSIFSAAVDELLPE-PTEAFPD 93
Cdd:pfam14551 7 FLEEFrEDGDGEFKYRDQLREMIEREQRSLEVDLDDLREF---DPDLAEALLENPYEYLPLFEEALKEVVKElSEDPDYA 83
|
...
gi 1789577082 94 DDH 96
Cdd:pfam14551 84 EEE 86
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
139-638 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 772.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 139 RPSTIREVKASHIGQLVRISGIVTRCSDVKPLMAVAVYTCEDCGHEIYQEVTSRVFMPLFKCPSSRCRLNSKagNPILQL 218
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP--FSLNHE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 219 RaSKFLKFQEAKMQELAEHVPKGHIPRSMTVHLRGELTRKVSPGDVVEFSGIFLPIPYtGFKALRAGLVAD--TYLEATS 296
Cdd:smart00350 79 R-STFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPY-GFKLNTVKGLPVfaTYIEANH 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 297 VTH--FKKKYEEYEFQ-----KDEEEQIARLAEDGDIYNKLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGD 369
Cdd:smart00350 157 VRKldYKRSFEDSSFSvqslsDEEEEEIRKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 370 VHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESD 449
Cdd:smart00350 237 INILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 450 RTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWGRYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELA 529
Cdd:smart00350 317 RTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELA 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 530 KHVLHVHQT-EESPALGFE-PLEPNILRAYISAAR-RLSPYVPAELEEYIATAYSSIRQEEAKSNT-PHSYTTVRTLLSI 605
Cdd:smart00350 397 KHVVDLHRYsHPEEDEAFEpPLSQEKLRKYIAYAReKIKPKLSEEAADKLVKAYVDLRKEDSQTESrSSIPITVRQLESI 476
|
490 500 510
....*....|....*....|....*....|...
gi 1789577082 606 LRISAALARLRFSESVAQSDVDEALRLMQMSKI 638
Cdd:smart00350 477 IRLSEAHAKMRLSDVVEEADVEEAIRLLRESII 509
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
329-636 |
0e+00 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 587.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 329 KLSRSLAPEIYGHEDIKKALLLLLVGAPHRQlKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVG 408
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 409 LTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWG 488
Cdd:cd17758 80 LTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 489 RYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVHQTEESPALGFEPLEPNILRAYISAARRLSPYV 568
Cdd:cd17758 160 RYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDFEPLDPKLLRAYIALAKRKRPTV 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1789577082 569 PAELEEYIATAYSSIRQEEAKSNtPHSYTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQMS 636
Cdd:cd17758 240 PPALADYIVQAYVEMRQEAKRSK-DFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
14-669 |
0e+00 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 556.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 14 KGFLENFadangrsKYMEILQEVSNR--KIRAIQVDLDDLFNYkdeSEEFLGRLTENTRRYVSIFSAAVDELLPEPTEaf 91
Cdd:COG1241 10 EEFLRRY-------KYRDEILELAQEypEKRSLVVDYNDLYSF---DPDLADDLLENPDEVLEAAEEALREIDLEPYD-- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 92 pDDDHDIlmtqraddgtdNPDVSDPHQQIPseikryyevyfkapskgrpstIREVKASHIGQLVRISGIVTRCSDVKPLM 171
Cdd:COG1241 78 -VSLGDA-----------HVRITNLPETVP---------------------IRDIRSDHIGKLISVEGIVRKATEVKPKI 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 172 AVAVYTCEDCGHEIYQEVTSRVFMPLFKCPSsrCrlnSKAGNPILQLRASKFLKFQEAKMQELAEHVPKGHIPRSMTVHL 251
Cdd:COG1241 125 TEAAFECPRCGTETYVPQTGEKLQEPHECPG--C---GRQGPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVIL 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 252 RGELTRKVSPGDVVEFSGIFLPIPYTGFKALRAglVADTYLEATSVTHFKKKYEEYEFQKDEEEQIARLAEDGDIYNKLS 331
Cdd:COG1241 200 EDDLVGEVRPGDRVTVTGILRIEQRTSGRGKST--IFDLYLEANSIEVEEKEFEEIEITEEDEEKIKELSKDPDIYEKII 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 332 RSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTA 411
Cdd:COG1241 278 ASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTA 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 412 AVMRDQV-TNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWGRY 490
Cdd:COG1241 358 AAVRDDFgTGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRF 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 491 DLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVHQTEESPALGFE--------PLEPNILRAYISAAR 562
Cdd:COG1241 438 DPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVHRAGELLEQEIEeeteevkpEIDPDLLRKYIAYAR 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 563 R-LSPYVPAELEEYIATAYSSIRQEEAKSNTPHSyTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQmskISLy 641
Cdd:COG1241 518 RnVFPVLTEEAKDLIEDFYVDMRKKGEDEDSPVP-ITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVD---SCL- 592
|
650 660
....*....|....*....|....*...
gi 1789577082 642 addrQKAGLDAISDTYSIIRDEAARSKK 669
Cdd:COG1241 593 ----KDVGVDPETGKFDIDVIETGTSKS 616
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
14-634 |
0e+00 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 540.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 14 KGFLENFADANGRSKYMEILQEVSNRKIRAIQVDLDDLFNYkdeSEEFLGRLTENTRRYVSIFSAAVDELLPEPTEAFPD 93
Cdd:NF040949 6 KEFIRTFRDSFGNEKYKERIFEMIAMRKRSLVVDFNDLYMF---DPELADLLIEKPDEVLPAASKALKEIVEEEDPEYAE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 94 DDHDIlmtqraddgtdNPDVSDPHQQIPseikryyevyfkapskgrpstIREVKASHIGQLVRISGIVTRCSDVKPLMAV 173
Cdd:NF040949 83 EVAKF-----------HVRFRNLPRTVP---------------------LRDLRSEYIGKLIAVEGIVTRTTPVKPRIVK 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 174 AVYTCEDCGHEIY-----QEVTSRVFMPLfKCPssRCrlnSKAGNPILQLRASKFLKFQEAKMQELAEHVPKGHIPRSMT 248
Cdd:NF040949 131 AVFRCRDCGCEFEwpeeeEESYEIVEPPT-VCP--VC---GKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIE 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 249 VHLRGELTRKVSPGDVVEFSGIFLPIPYTGFKALRAGLVaDTYLEATSVTHFKKKYEEYEFQKDEEEQIARLAEDGDIYN 328
Cdd:NF040949 205 VVLEDDLVDTARPGDRVTVTGILRIKPDSSLKKGSRPIF-KNYIEANHIEVSQKELEEVEITEEDEEKILELAKDPWIRE 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 329 KLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVG 408
Cdd:NF040949 284 KIIASIAPSIYGHWEIKEAIALLLFGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAG 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 409 LTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWG 488
Cdd:NF040949 364 LTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFG 443
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 489 RYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVHQTEESpalgFEP-LEPNILRAYISAARR---- 563
Cdd:NF040949 444 RYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDVHSGKEK----VKPeIDPDLLKKYIAYARKyvrp 519
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1789577082 564 -LSPYVPAELEEYiataYSSIRQEEAKSNTPHS--YTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQ 634
Cdd:NF040949 520 kLTEEAKKLIEDF----YVEMRKSSKSSEDPDSpiPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLML 589
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
313-536 |
3.76e-145 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 422.71 E-value: 3.76e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 313 EEEQIARLAEDGDIYNKLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINV 392
Cdd:pfam00493 1 DEEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 393 APRGVYTTGKGSSGVGLTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTS 472
Cdd:pfam00493 81 APRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVAT 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1789577082 473 LNARTAVLAAANPAWGRYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVH 536
Cdd:pfam00493 161 LNARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
329-636 |
5.99e-140 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 412.89 E-value: 5.99e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 329 KLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVG 408
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 409 LTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWG 488
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 489 RYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVH---QTEESPALGFE--PLEPNILRAYISAARR 563
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHrgsDPEEQVKPEEDgiPIDIELLRKYILYARQ 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1789577082 564 LSPYVPAELEEYIATAYSSIRQEEAKSNTphSYTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQMS 636
Cdd:cd17706 241 IHPKISEEAREKLVRWYVELRKESERRST--IPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
329-636 |
6.54e-127 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 379.42 E-value: 6.54e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 329 KLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVG 408
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 409 LTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWG 488
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 489 RYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVH-----QTEESPALGFEPLEpnILRAYISAAR- 562
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHasarkASQSQENEGEIPIS--KLKRYIAYCRa 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1789577082 563 RLSPYVPAELEEYIATAYSSIR-----QEEAKSNTPHSYTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQMS 636
Cdd:cd17756 239 KCAPRLSEEAAEKLSNHYVTIRkdvrqNELESDNRSSIPITVRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
329-636 |
2.74e-123 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 369.78 E-value: 2.74e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 329 KLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVG 408
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 409 LTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWG 488
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 489 RYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVHQTEEspALGFEPLEPNILRAYISAARRLSPYV 568
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSKRE--EAIEPPFTAEQLKRYIAYARTFKPKL 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1789577082 569 PAELEEYIATAYSSIRQEEAKSNTPHSY-TTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQMS 636
Cdd:cd17757 239 TKEAKDELVEQYKELRQDDASGSTRSSYrITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
330-634 |
3.72e-120 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 361.40 E-value: 3.72e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 330 LSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGL 409
Cdd:cd17754 2 LSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 410 TAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWGR 489
Cdd:cd17754 82 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 490 YDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVHQTEEspalgfeplepnILRAYISAAR-RLSPYV 568
Cdd:cd17754 162 YDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRYIK------------FLRKYIHYAKeRIKPKL 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1789577082 569 PAELEEYIATAYSSIRQEEAKSNTPH--SYTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQ 634
Cdd:cd17754 230 TQEAAEYIAEEYADLRNDDNTKTDKArtSPITARTLETLIRLATAHAKARLSKTVDKVDAEVALNLLR 297
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
329-634 |
1.03e-119 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 360.61 E-value: 1.03e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 329 KLSRSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVG 408
Cdd:cd17761 2 KIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAAG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 409 LTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWG 488
Cdd:cd17761 82 LTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKFG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 489 RYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVHQTEESPALGFEpLEPNILRAYISAARR-LSPY 567
Cdd:cd17761 162 RFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGEMREIKPE-IDPDLLRKYIAYARKnVRPV 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1789577082 568 VPAELEEYIATAYSSIRQEEAKSNTPHSYTTvRTLLSILRISAALARLRFSESVAQSDVDEALRLMQ 634
Cdd:cd17761 241 LTEEAKQLIKDFYVEMRKSGQETPSPVPITA-RQLEALVRLSEASARMRLSQEVTLEDAERAIRIML 306
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
329-633 |
1.16e-119 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 360.60 E-value: 1.16e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 329 KLSRSLAPEIYGHEDIKKALLLLLVGAPHRQL-KDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGV 407
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFtKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 408 GLTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAW 487
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 488 GRYDLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVHQTEESPALGFEPLEPNILRAYISAAR-RLSP 566
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHIQDEVLDVEVLTDYISYAReHIHP 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1789577082 567 YVPAELEEYIATAYSSIRQEEAKSNTPHSYTTvRTLLSILRISAALARLRFSESVAQSDVDEALRLM 633
Cdd:cd17755 241 KLSEEAAQELVQAYVDMRKMGSDARKRITATP-RQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLI 306
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
333-633 |
1.80e-113 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 345.20 E-value: 1.80e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 333 SLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTAA 412
Cdd:cd17753 5 SIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVGLTAS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 413 VMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWGRYDL 492
Cdd:cd17753 85 VRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGGRYNP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 493 RRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLHVH--------QTEESPALGFEPLEPN----------IL 554
Cdd:cd17753 165 TLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHvrshpendEDREGEEEKNQRQRPKetkvepipqeLL 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 555 RAYISAAR-RLSPYVPAELEEYIATAYSSIRQEeakSNTPHSY-TTVRTLLSILRISAALARLRFSESVAQSDVDEALRL 632
Cdd:cd17753 245 RKYIHYAReKVRPKLNQMDMDKVSRVYADLRKE---SMATGSLpITVRHLESIIRISEAHAKMHLREYVSEEDVDMAIRV 321
|
.
gi 1789577082 633 M 633
Cdd:cd17753 322 M 322
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
142-636 |
1.79e-89 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 299.60 E-value: 1.79e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 142 TIREVKASHIGQLVRISGIVTRCSDVKPLMAVAVYTC-----------EDCGHEIYQEVTS-RVFMPL----------FK 199
Cdd:PTZ00111 217 CVGNLEPSMADSLVQFSGTVVRQTWIVPEITMACFRCrgqkkiglndyQPCTCEHYEYVIQgEVNEPLlcnecnskytFE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 200 CPSSRCRLNSKAGNPILQLRASKFLKFQEAKMQELAEHVPKGHI----PRSMTVHLRGELTRKVSPGDVVEFSGIFLPIP 275
Cdd:PTZ00111 297 LNHNMCVYSTKKIVKLLQSNSSLNNPDKDGLDNSVDNSGLNGEIymkdNEVINLNLYDDLIDSVKTGDRVTVVGILKVTP 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 276 -------------YTGFKALRAGLVADTYLEATSVTHFKKKYEEYEFQKDEEEQIARLAEDGDIYNKLSRSLAPEIYGHE 342
Cdd:PTZ00111 377 irtsttrrtlkslYTYFVNVIHVKVINSTNANQPEKGLKYLGNENDFSDLQVYKILELSRNPMIYRILLDSFAPSIKARN 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 343 DIKKALLLLLVGAPHRQLKDGM---------KIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTAAV 413
Cdd:PTZ00111 457 NVKIGLLCQLFSGNKNSSDFNKspdacykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASI 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 414 -MRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWGRYDL 492
Cdd:PTZ00111 537 kFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNK 616
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 493 RRTPAENINLPPALLSRFDLLWLILDRADMDSD----LELAKHVLHVHQTEES--------------------PALGFEP 548
Cdd:PTZ00111 617 NKAVIENINISPSLFTRFDLIYLVLDHIDQDTDqlisLSIAKDFLLPHMTGSGndedtydrsntmhvedeslrSEKDYNK 696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 549 LEPNILRAYISAAR-RLSPYVPAELEEYIATAYSSIRQEE----------------------AKSNTPHSYTTVRTLLSI 605
Cdd:PTZ00111 697 NDLDMLRMYIKFSKlHCFPKLSDEAKKVITREYVKMRQGNfqtsnldelehaqedddddlyyQSSGTRMIYVSSRMISSI 776
|
570 580 590
....*....|....*....|....*....|.
gi 1789577082 606 LRISAALARLRFSESVAQSDVDEALRLMQMS 636
Cdd:PTZ00111 777 IRISVSLARMRLSTVVTPADALQAVQIVKSS 807
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
332-636 |
1.56e-83 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 266.33 E-value: 1.56e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 332 RSLAPEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTA 411
Cdd:cd17760 4 ASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGLTV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 412 AVMRDqvTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAwGRYD 491
Cdd:cd17760 84 TAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK-GQYD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 492 LRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHVLhvhQTEESPALGFEPLEPNILRAYISAARRLSPYVPAE 571
Cdd:cd17760 161 PNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFIL---ENKGEPSKSSKLWSMEKMRTYFCLIKNLRPVLSDE 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1789577082 572 LEEYIATAYSSIRQEEAKSNtphSYTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQMS 636
Cdd:cd17760 238 ANAILLRYYQLQRQSDCRNA---ARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
333-636 |
3.45e-79 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 254.77 E-value: 3.45e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 333 SLAPEIYGHEDIKKALLLLLVGA--PHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLT 410
Cdd:cd17759 5 SLCPAIYGHELVKAGLLLSLFGGkqKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTTSGLT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 411 AAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDeSDRTAIHEVMEQQTVSIAKAGITTSLNARTAVLAAANPAWGRY 490
Cdd:cd17759 85 VTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMG-SQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPVGGHY 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 491 DLRRTPAENINLPPALLSRFDLLWLILDRADMDSDLELAKHvlhvhqteespalgfeplePNILRAYISAARR-LSPYVP 569
Cdd:cd17759 164 NKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH-------------------HQLLRKYISYARQyVNPVLS 224
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1789577082 570 AELEEYIATAYSSIR-QEEAKSNTPhsyTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQMS 636
Cdd:cd17759 225 KDASEALQEFYLELRkQNQLADSSP---ITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
143-275 |
2.32e-48 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 166.12 E-value: 2.32e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 143 IREVKASHIGQLVRISGIVTRCSDVKPLMAVAVYTCEDCGHEIYQEVTsrvfmPLFKCPSSRCrlNSKAGNpILQLRASK 222
Cdd:pfam17207 2 IRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKIT-----EPTKCPNPEC--GNKDPF-KLVHEKSK 73
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1789577082 223 FLKFQEAKMQELAEHVPKGHIPRSMTVHLRGELTRKVSPGDVVEFSGIFLPIP 275
Cdd:pfam17207 74 FVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
552-637 |
5.44e-24 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 96.07 E-value: 5.44e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 552 NILRAYISAAR-RLSPYVPAELEEYIATAYSSIRQEEAKSNTPHsYTTVRTLLSILRISAALARLRFSESVAQSDVDEAL 630
Cdd:pfam17855 1 ELLRKYIAYAReKIKPKLSEEAREKLVDAYVELRKESTGSGSSI-PITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAI 79
|
....*..
gi 1789577082 631 RLMQMSK 637
Cdd:pfam17855 80 RLLKESL 86
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
16-96 |
3.46e-11 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 60.00 E-value: 3.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 16 FLENF-ADANGRSKYMEILQEVSNRKIRAIQVDLDDLFNYkdeSEEFLGRLTENTRRYVSIFSAAVDELLPE-PTEAFPD 93
Cdd:pfam14551 7 FLEEFrEDGDGEFKYRDQLREMIEREQRSLEVDLDDLREF---DPDLAEALLENPYEYLPLFEEALKEVVKElSEDPDYA 83
|
...
gi 1789577082 94 DDH 96
Cdd:pfam14551 84 EEE 86
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
371-510 |
1.14e-03 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 39.58 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 371 HICLMGDPGVAKSQLLKHIINVAPRGVYTTgkgssgVGLTAAVMRDQVTNEMVLEGGALVLADM---------GICAIDE 441
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVFY------VQLTRDTTEEDLFGRRNIDPGGASWVDGplvraaregEIAVLDE 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 442 FDKMDESDRTAIHEVMEQQTVSIAKAG-ITTSLNARTAVLAAANPAwgrydlrrtPAENINLPPALLSRF 510
Cdd:pfam07728 75 INRANPDVLNSLLSLLDERRLLLPDGGeLVKAAPDGFRLIATMNPL---------DRGLNELSPALRSRF 135
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
357-512 |
1.92e-03 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 39.44 E-value: 1.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 357 HRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPRGVYTTGKGSSGVGLTAAVMRDQVTNEMV-LEGGALVLADMG 435
Cdd:cd00009 7 IEALREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFLVrLLFELAEKAKPG 86
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1789577082 436 ICAIDEFDKMDESDRTAIHEVMEQQTVSIAKagittslNARTAVLAAANpawgrydlrrtPAENINLPPALLSRFDL 512
Cdd:cd00009 87 VLFIDEIDSLSRGAQNALLRVLETLNDLRID-------RENVRVIGATN-----------RPLLGDLDRALYDRLDI 145
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
337-530 |
2.73e-03 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 40.66 E-value: 2.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 337 EIYGHEDIKKALLLLLVGA-PHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHI--------INVAPRGVYttgkgSSGV 407
Cdd:COG0464 158 DLGGLEEVKEELRELVALPlKRPELREEYGLPPPRGLLLYGPPGTGKTLLARALagelglplIEVDLSDLV-----SKYV 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1789577082 408 GLTAAVMRDqvtnemVLEGgALVLADmGICAIDEFDKM-----DESDRTAIHEV------MEQqtvsiakagittsLNAR 476
Cdd:COG0464 233 GETEKNLRE------VFDK-ARGLAP-CVLFIDEADALagkrgEVGDGVGRRVVntllteMEE-------------LRSD 291
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1789577082 477 TAVLAAANPAWgrydlrrtpaeniNLPPALLSRFD---------------LLWLILDRADMDSDLELAK 530
Cdd:COG0464 292 VVVIAATNRPD-------------LLDPALLRRFDeiiffplpdaeerleIFRIHLRKRPLDEDVDLEE 347
|
|
| |
