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Conserved domains on  [gi|1915353290|dbj|BBW85835|]
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membrane protein [Klebsiella pneumoniae]

Protein Classification

HPP family protein( domain architecture ID 10523216)

HPP family protein is an integral membrane protein with four transmembrane spanning helices

Gene Ontology:  GO:0016020

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HPP pfam04982
HPP family; These proteins are integral membrane proteins with four transmembrane spanning ...
 61-181 5.97e-36

HPP family; These proteins are integral membrane proteins with four transmembrane spanning helices. The most conserved region of the alignment is a motif HPP. The function of these proteins is uncertain but they may be transporters.


:

Pssm-ID: 461506  Cd Length: 122  Bit Score: 123.78  E-value: 5.97e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1915353290  61 FIAPMGASAVLLFGVPSSPLAQPWSIVGGNVLSALIGVTVGMLVPDAALACGLA--AALAIAGMYFLRCLHPPGGAVALT 138
Cdd:pfam04982   1 LIASFGASAVLLFGAPESPLAQPRNVVGGHLISALIGVAIAKLFGLSLLWLAAAlaVALAIALMQLTRTLHPPAGATALL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1915353290 139 AILGGAgVHSEGYHFVLTPVLLNSLMLALLAIVFNNLVGRRYP 181
Cdd:pfam04982  81 AVLGGP-IHALGWWFVLVPVLLGSLLLVLVALLVNNLTGRRYP 122
 
Name Accession Description Interval E-value
HPP pfam04982
HPP family; These proteins are integral membrane proteins with four transmembrane spanning ...
 61-181 5.97e-36

HPP family; These proteins are integral membrane proteins with four transmembrane spanning helices. The most conserved region of the alignment is a motif HPP. The function of these proteins is uncertain but they may be transporters.


Pssm-ID: 461506  Cd Length: 122  Bit Score: 123.78  E-value: 5.97e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1915353290  61 FIAPMGASAVLLFGVPSSPLAQPWSIVGGNVLSALIGVTVGMLVPDAALACGLA--AALAIAGMYFLRCLHPPGGAVALT 138
Cdd:pfam04982   1 LIASFGASAVLLFGAPESPLAQPRNVVGGHLISALIGVAIAKLFGLSLLWLAAAlaVALAIALMQLTRTLHPPAGATALL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1915353290 139 AILGGAgVHSEGYHFVLTPVLLNSLMLALLAIVFNNLVGRRYP 181
Cdd:pfam04982  81 AVLGGP-IHALGWWFVLVPVLLGSLLLVLVALLVNNLTGRRYP 122
 
Name Accession Description Interval E-value
HPP pfam04982
HPP family; These proteins are integral membrane proteins with four transmembrane spanning ...
 61-181 5.97e-36

HPP family; These proteins are integral membrane proteins with four transmembrane spanning helices. The most conserved region of the alignment is a motif HPP. The function of these proteins is uncertain but they may be transporters.


Pssm-ID: 461506  Cd Length: 122  Bit Score: 123.78  E-value: 5.97e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1915353290  61 FIAPMGASAVLLFGVPSSPLAQPWSIVGGNVLSALIGVTVGMLVPDAALACGLA--AALAIAGMYFLRCLHPPGGAVALT 138
Cdd:pfam04982   1 LIASFGASAVLLFGAPESPLAQPRNVVGGHLISALIGVAIAKLFGLSLLWLAAAlaVALAIALMQLTRTLHPPAGATALL 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1915353290 139 AILGGAgVHSEGYHFVLTPVLLNSLMLALLAIVFNNLVGRRYP 181
Cdd:pfam04982  81 AVLGGP-IHALGWWFVLVPVLLGSLLLVLVALLVNNLTGRRYP 122
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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