unnamed protein product [Homo sapiens]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| Mesd super family | cl10879 | Chaperone for wingless signalling and trafficking of LDL receptor; Mesd is a family of highly ... |
52-81 | 3.63e-11 | ||
Chaperone for wingless signalling and trafficking of LDL receptor; Mesd is a family of highly conserved proteins found from nematodes to humans. The final C-terminal residues, KEDL, are the endoplasmic reticulum retention sequence as it is an ER protein specifically required for the intracellular trafficking of members of the low-density lipoprotein family of receptors (LDLRs). The N- and C-terminal sequences are predicted to adopt a random coil conformation, with the exception of an isolated predicted helix within the N-terminal region, The central folded domain flanked by natively unstructured regions is the necessary structure for facilitating maturation of LRP6 (Low-Density Lipoprotein Receptor-Related Protein 6 Maturation). The actual alignment was detected with superfamily member pfam10185: Pssm-ID: 462985 Cd Length: 155 Bit Score: 57.08 E-value: 3.63e-11
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| Name | Accession | Description | Interval | E-value | ||
| Mesd | pfam10185 | Chaperone for wingless signalling and trafficking of LDL receptor; Mesd is a family of highly ... |
52-81 | 3.63e-11 | ||
Chaperone for wingless signalling and trafficking of LDL receptor; Mesd is a family of highly conserved proteins found from nematodes to humans. The final C-terminal residues, KEDL, are the endoplasmic reticulum retention sequence as it is an ER protein specifically required for the intracellular trafficking of members of the low-density lipoprotein family of receptors (LDLRs). The N- and C-terminal sequences are predicted to adopt a random coil conformation, with the exception of an isolated predicted helix within the N-terminal region, The central folded domain flanked by natively unstructured regions is the necessary structure for facilitating maturation of LRP6 (Low-Density Lipoprotein Receptor-Related Protein 6 Maturation). Pssm-ID: 462985 Cd Length: 155 Bit Score: 57.08 E-value: 3.63e-11
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| Name | Accession | Description | Interval | E-value | ||
| Mesd | pfam10185 | Chaperone for wingless signalling and trafficking of LDL receptor; Mesd is a family of highly ... |
52-81 | 3.63e-11 | ||
Chaperone for wingless signalling and trafficking of LDL receptor; Mesd is a family of highly conserved proteins found from nematodes to humans. The final C-terminal residues, KEDL, are the endoplasmic reticulum retention sequence as it is an ER protein specifically required for the intracellular trafficking of members of the low-density lipoprotein family of receptors (LDLRs). The N- and C-terminal sequences are predicted to adopt a random coil conformation, with the exception of an isolated predicted helix within the N-terminal region, The central folded domain flanked by natively unstructured regions is the necessary structure for facilitating maturation of LRP6 (Low-Density Lipoprotein Receptor-Related Protein 6 Maturation). Pssm-ID: 462985 Cd Length: 155 Bit Score: 57.08 E-value: 3.63e-11
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