|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
1-465 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 682.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 1 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSggRLYLQTRgSRFIKFQEMKMQEHSDQVPVGNIPRSITVL 80
Cdd:smart00350 33 LKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP--FSLNHER-STFIDFQKIKLQESPEEVPVGQLPRSVDVI 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 81 VEGENTRIAQPGDHVSVTGIFLPILrTGFRQVVQGLLSE--TYLEAHRIVK--MNKSEDDESGA----GELTREELRQIA 152
Cdd:smart00350 110 LDGDLVDKAKPGDRVEVTGIYRNVP-YGFKLNTVKGLPVfaTYIEANHVRKldYKRSFEDSSFSvqslSDEEEEEIRKLS 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 153 E-EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTG 230
Cdd:smart00350 189 KdPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNlPDGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTG 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 231 RGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILA 310
Cdd:smart00350 269 KGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLA 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 311 AANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSR-QPPSQFE-PLDMKLMRRYIA 388
Cdd:smart00350 349 AANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKHVVDLHRYSHpEEDEAFEpPLSQEKLRKYIA 428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 389 MCREK-QPMVPESLADYITAAYVEMRREAWASKDAT--YTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSK 465
Cdd:smart00350 429 YAREKiKPKLSEEAADKLVKAYVDLRKEDSQTESRSsiPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
159-464 |
0e+00 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 609.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 159 KLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGL 238
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKRGDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 239 TAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGR 318
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 319 YNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVP 398
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDFEPLDPKLLRAYIALAKRKRPTVP 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 193786225 399 ESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
Cdd:cd17758 241 PALADYIVQAYVEMRQEAKRSKDFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
1-462 |
1.26e-161 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 475.83 E-value: 1.26e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 1 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQtnrsgGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVL 80
Cdd:COG1241 124 ITEAAFECPRCGTETYVPQTGEKLQEPHECPGCGRQ-----GPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVI 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 81 VEGENTRIAQPGDHVSVTGIflpiLRTGFRQVVQGLLS--ETYLEAHRIVKMNKSEDDEsgagELTREELRQIAE----E 154
Cdd:COG1241 199 LEDDLVGEVRPGDRVTVTGI----LRIEQRTSGRGKSTifDLYLEANSIEVEEKEFEEI----EITEEDEEKIKElskdP 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 155 DFYEKLAASIAPEIYGHEDVKKALLLllvggvdQ--------SPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQ 226
Cdd:COG1241 271 DIYEKIIASIAPSIYGYEEIKEAIAL-------QlfggvpkvLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGV 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 227 YTTGRGSSGVGLTAAVLRDSVS-GELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNAR 305
Cdd:COG1241 344 YTSGKGSTAAGLTAAAVRDDFGtGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNAR 423
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 306 CSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFE--------P 377
Cdd:COG1241 424 CSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVHRAGELLEQEIEeeteevkpE 503
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 378 LDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNE 456
Cdd:COG1241 504 IDPDLLRKYIAYARRNvFPVLTEEAKDLIEDFYVDMRKKGEDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAER 583
|
....*.
gi 193786225 457 AIRLME 462
Cdd:COG1241 584 AIRLVD 589
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
1-462 |
3.70e-153 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 454.00 E-value: 3.70e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 1 MVVATYTCDQCGAETYQPiQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVL 80
Cdd:NF040949 128 IVKAVFRCRDCGCEFEWP-EEEEESYEIVEPPTVCPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVV 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 81 VEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSeTYLEAHRIVKMNKsEDDESgagELTREELRQIAE----EDF 156
Cdd:NF040949 207 LEDDLVDTARPGDRVTVTGILRIKPDSSLKKGSRPIFK-NYIEANHIEVSQK-ELEEV---EITEEDEEKILElakdPWI 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 157 YEKLAASIAPEIYGHEDVKKALLLLL-VGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSG 235
Cdd:NF040949 282 REKIIASIAPSIYGHWEIKEAIALLLfGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTA 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 236 VGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPA 315
Cdd:NF040949 362 AGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPK 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 316 YGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSrqppSQFEP-LDMKLMRRYIAMCREK- 393
Cdd:NF040949 442 FGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDVHSGK----EKVKPeIDPDLLKKYIAYARKYv 517
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 193786225 394 QPMVPESLADYITAAYVEMRREAWASKD---ATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLME 462
Cdd:NF040949 518 RPKLTEEAKKLIEDFYVEMRKSSKSSEDpdsPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLML 589
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
146-365 |
1.07e-134 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 389.97 E-value: 1.07e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 146 EELRQIA-EEDFYEKLAASIAPEIYGHEDVKKALLLLLVG-GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAP 223
Cdd:pfam00493 3 EEIKELAkRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGgVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIAP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 224 RSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLN 303
Cdd:pfam00493 83 RAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATLN 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 193786225 304 ARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVH 365
Cdd:pfam00493 163 ARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
91-464 |
1.66e-83 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 278.42 E-value: 1.66e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 91 PGDHVSVTGIF--LPIlRTGFRQVVQGLLSETYLEA-H-RIVKMNKSEDDESG------AGELTREELRQIAE----EDF 156
Cdd:PTZ00111 362 TGDRVTVVGILkvTPI-RTSTTRRTLKSLYTYFVNViHvKVINSTNANQPEKGlkylgnENDFSDLQVYKILElsrnPMI 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 157 YEKLAASIAPEIYGHEDVKK----------ALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQ 226
Cdd:PTZ00111 441 YRILLDSFAPSIKARNNVKIgllcqlfsgnKNSSDFNKSPDACYKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSI 520
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 227 YTTGRGSSGVGLTAAV-LRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNAR 305
Cdd:PTZ00111 521 YTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAE 600
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 306 CSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHI-----------------TY----- 363
Cdd:PTZ00111 601 TAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIakdfllphmtgsgndedTYdrsnt 680
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 364 --VHQHSRQPPSQFEPLDMKLMRRYIAMCR-EKQPMVPESLADYITAAYVEMRREAWASKD------------------- 421
Cdd:PTZ00111 681 mhVEDESLRSEKDYNKNDLDMLRMYIKFSKlHCFPKLSDEAKKVITREYVKMRQGNFQTSNldelehaqedddddlyyqs 760
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 193786225 422 ----ATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
Cdd:PTZ00111 761 sgtrMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSS 807
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
1-465 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 682.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 1 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSggRLYLQTRgSRFIKFQEMKMQEHSDQVPVGNIPRSITVL 80
Cdd:smart00350 33 LKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP--FSLNHER-STFIDFQKIKLQESPEEVPVGQLPRSVDVI 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 81 VEGENTRIAQPGDHVSVTGIFLPILrTGFRQVVQGLLSE--TYLEAHRIVK--MNKSEDDESGA----GELTREELRQIA 152
Cdd:smart00350 110 LDGDLVDKAKPGDRVEVTGIYRNVP-YGFKLNTVKGLPVfaTYIEANHVRKldYKRSFEDSSFSvqslSDEEEEEIRKLS 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 153 E-EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTG 230
Cdd:smart00350 189 KdPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNlPDGMKIRGDINILLCGDPGTAKSQLLKYVEKTAPRAVYTTG 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 231 RGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILA 310
Cdd:smart00350 269 KGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSDRTAIHEAMEQQTISIAKAGITTTLNARCSVLA 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 311 AANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSR-QPPSQFE-PLDMKLMRRYIA 388
Cdd:smart00350 349 AANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELAKHVVDLHRYSHpEEDEAFEpPLSQEKLRKYIA 428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 389 MCREK-QPMVPESLADYITAAYVEMRREAWASKDAT--YTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSK 465
Cdd:smart00350 429 YAREKiKPKLSEEAADKLVKAYVDLRKEDSQTESRSsiPITVRQLESIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
159-464 |
0e+00 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 609.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 159 KLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGL 238
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKRGDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 239 TAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGR 318
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 319 YNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVP 398
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDFEPLDPKLLRAYIALAKRKRPTVP 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 193786225 399 ESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
Cdd:cd17758 241 PALADYIVQAYVEMRQEAKRSKDFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
1-462 |
1.26e-161 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 475.83 E-value: 1.26e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 1 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQtnrsgGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVL 80
Cdd:COG1241 124 ITEAAFECPRCGTETYVPQTGEKLQEPHECPGCGRQ-----GPFKLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVI 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 81 VEGENTRIAQPGDHVSVTGIflpiLRTGFRQVVQGLLS--ETYLEAHRIVKMNKSEDDEsgagELTREELRQIAE----E 154
Cdd:COG1241 199 LEDDLVGEVRPGDRVTVTGI----LRIEQRTSGRGKSTifDLYLEANSIEVEEKEFEEI----EITEEDEEKIKElskdP 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 155 DFYEKLAASIAPEIYGHEDVKKALLLllvggvdQ--------SPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQ 226
Cdd:COG1241 271 DIYEKIIASIAPSIYGYEEIKEAIAL-------QlfggvpkvLPDGSRIRGDIHILLVGDPGTAKSQLLRYAARLAPRGV 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 227 YTTGRGSSGVGLTAAVLRDSVS-GELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNAR 305
Cdd:COG1241 344 YTSGKGSTAAGLTAAAVRDDFGtGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQTISIAKAGIVATLNAR 423
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 306 CSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFE--------P 377
Cdd:COG1241 424 CSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVHRAGELLEQEIEeeteevkpE 503
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 378 LDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNE 456
Cdd:COG1241 504 IDPDLLRKYIAYARRNvFPVLTEEAKDLIEDFYVDMRKKGEDEDSPVPITARQLEALIRLAEASARMRLSDTVTEEDAER 583
|
....*.
gi 193786225 457 AIRLME 462
Cdd:COG1241 584 AIRLVD 589
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
1-462 |
3.70e-153 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 454.00 E-value: 3.70e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 1 MVVATYTCDQCGAETYQPiQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVL 80
Cdd:NF040949 128 IVKAVFRCRDCGCEFEWP-EEEEESYEIVEPPTVCPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVV 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 81 VEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSeTYLEAHRIVKMNKsEDDESgagELTREELRQIAE----EDF 156
Cdd:NF040949 207 LEDDLVDTARPGDRVTVTGILRIKPDSSLKKGSRPIFK-NYIEANHIEVSQK-ELEEV---EITEEDEEKILElakdPWI 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 157 YEKLAASIAPEIYGHEDVKKALLLLL-VGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSG 235
Cdd:NF040949 282 REKIIASIAPSIYGHWEIKEAIALLLfGGVPKVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTA 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 236 VGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPA 315
Cdd:NF040949 362 AGLTAAVVRDKLTGEYYLEAGALVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPK 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 316 YGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSrqppSQFEP-LDMKLMRRYIAMCREK- 393
Cdd:NF040949 442 FGRYDPNRSVAENIDLPPTILSRFDLIFVIRDKPNEERDRRLARHILDVHSGK----EKVKPeIDPDLLKKYIAYARKYv 517
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 193786225 394 QPMVPESLADYITAAYVEMRREAWASKD---ATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLME 462
Cdd:NF040949 518 RPKLTEEAKKLIEDFYVEMRKSSKSSEDpdsPIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLML 589
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
159-464 |
3.23e-141 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 410.20 E-value: 3.23e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 159 KLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 237
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKIlEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 238 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 317
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 318 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHS-----RQPPSQFEPLDMKLMRRYIAMCRE 392
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSdpeeqVKPEEDGIPIDIELLRKYILYARQ 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 193786225 393 KQPMVPESLADYITAAYVEMRREAwASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
Cdd:cd17706 241 IHPKISEEAREKLVRWYVELRKES-ERRSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
146-365 |
1.07e-134 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 389.97 E-value: 1.07e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 146 EELRQIA-EEDFYEKLAASIAPEIYGHEDVKKALLLLLVG-GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAP 223
Cdd:pfam00493 3 EEIKELAkRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGgVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIAP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 224 RSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLN 303
Cdd:pfam00493 83 RAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATLN 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 193786225 304 ARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVH 365
Cdd:pfam00493 163 ARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
159-461 |
3.54e-123 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 364.06 E-value: 3.54e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 159 KLAASIAPEIYGHEDVKKALLLLL--VGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV 236
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLfgGTRKDFTKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 237 GLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAY 316
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 317 GRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREK-QP 395
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHIQDEVLDVEVLTDYISYAREHiHP 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 193786225 396 MVPESLADYITAAYVEMRReAWASKDATYTSA-RTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 461
Cdd:cd17755 241 KLSEEAAQELVQAYVDMRK-MGSDARKRITATpRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLI 306
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
159-464 |
2.36e-122 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 362.09 E-value: 2.36e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 159 KLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 237
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRlPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 238 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 317
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 318 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSR--QPPSQFEP-LDMKLMRRYIAMCREK- 393
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARkaSQSQENEGeIPISKLKRYIAYCRAKc 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 193786225 394 QPMVPESLADYITAAYVEMRREAWASKDATYTSA------RTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
Cdd:cd17756 241 APRLSEEAAEKLSNHYVTIRKDVRQNELESDNRSsipitvRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
158-461 |
5.92e-121 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 358.30 E-value: 5.92e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 158 EKLAASIAPEIYGHEDVKKALLLLL-VGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV 236
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLfGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 237 GLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAY 316
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 317 GRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRqpPSQFEP-LDMKLMRRYIAMCREK-Q 394
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGE--MREIKPeIDPDLLRKYIAYARKNvR 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 193786225 395 PMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 461
Cdd:cd17761 239 PVLTEEAKQLIKDFYVEMRKSGQETPSPVPITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIM 305
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
159-461 |
4.57e-119 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 354.06 E-value: 4.57e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 159 KLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGM-KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 237
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKhRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 238 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 317
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 318 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHItyVHQHSRQPPS--------------------QFEP 377
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFV--VGSHVRSHPEndedregeeeknqrqrpketKVEP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 378 LDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDATYTsARTLLAILRLSTALARLRMVDVVEKEDVNE 456
Cdd:cd17753 239 IPQELLRKYIHYAREKvRPKLNQMDMDKVSRVYADLRKESMATGSLPIT-VRHLESIIRISEAHAKMHLREYVSEEDVDM 317
|
....*
gi 193786225 457 AIRLM 461
Cdd:cd17753 318 AIRVM 322
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
159-464 |
7.97e-119 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 352.83 E-value: 7.97e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 159 KLAASIAPEIYGHEDVKKALLLLLVG-GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 237
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGgVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 238 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 317
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 318 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHItyVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMV 397
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHI--VDLHSKREEAIEPPFTAEQLKRYIAYARTFKPKL 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 193786225 398 PESLADYITAAYVEMR-REAWASKDATY-TSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
Cdd:cd17757 239 TKEAKDELVEQYKELRqDDASGSTRSSYrITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
160-461 |
2.95e-114 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 340.60 E-value: 2.95e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 160 LAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGL 238
Cdd:cd17754 2 LSKSLAPSIYGHEYIKKAILLMLLGGVEKNlENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 239 TAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGR 318
Cdd:cd17754 82 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 319 YNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHsrqppsqfepldMKLMRRYIAMCREK-QPMV 397
Cdd:cd17754 162 YDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------IKFLRKYIHYAKERiKPKL 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 193786225 398 PESLADYITAAYVEMRREAWASKDATYTS---ARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 461
Cdd:cd17754 230 TQEAAEYIAEEYADLRNDDNTKTDKARTSpitARTLETLIRLATAHAKARLSKTVDKVDAEVALNLL 296
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
91-464 |
1.66e-83 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 278.42 E-value: 1.66e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 91 PGDHVSVTGIF--LPIlRTGFRQVVQGLLSETYLEA-H-RIVKMNKSEDDESG------AGELTREELRQIAE----EDF 156
Cdd:PTZ00111 362 TGDRVTVVGILkvTPI-RTSTTRRTLKSLYTYFVNViHvKVINSTNANQPEKGlkylgnENDFSDLQVYKILElsrnPMI 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 157 YEKLAASIAPEIYGHEDVKK----------ALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQ 226
Cdd:PTZ00111 441 YRILLDSFAPSIKARNNVKIgllcqlfsgnKNSSDFNKSPDACYKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSI 520
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 227 YTTGRGSSGVGLTAAV-LRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNAR 305
Cdd:PTZ00111 521 YTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAE 600
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 306 CSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHI-----------------TY----- 363
Cdd:PTZ00111 601 TAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIakdfllphmtgsgndedTYdrsnt 680
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 364 --VHQHSRQPPSQFEPLDMKLMRRYIAMCR-EKQPMVPESLADYITAAYVEMRREAWASKD------------------- 421
Cdd:PTZ00111 681 mhVEDESLRSEKDYNKNDLDMLRMYIKFSKlHCFPKLSDEAKKVITREYVKMRQGNFQTSNldelehaqedddddlyyqs 760
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 193786225 422 ----ATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
Cdd:PTZ00111 761 sgtrMIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSS 807
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
160-464 |
1.99e-82 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 259.01 E-value: 1.99e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 160 LAASIAPEIYGHEDVKKALLLLLV---GGVDQSprGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV 236
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAggvQRIDAS--GTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 237 GLTAAVLRDSvsGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAy 316
Cdd:cd17760 80 GLTVTAVKDG--GEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 317 GRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITyvhqHSRQPPSQFEPL-DMKLMRRYIAMCREKQP 395
Cdd:cd17760 157 GQYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFIL----ENKGEPSKSSKLwSMEKMRTYFCLIKNLRP 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 193786225 396 MVPESlADYITAAYVEMRREAwASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
Cdd:cd17760 233 VLSDE-ANAILLRYYQLQRQS-DCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
160-464 |
1.66e-74 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 238.20 E-value: 1.66e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 160 LAASIAPEIYGHEDVKKALLLL----LVGGVDQSPRgMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSG 235
Cdd:cd17759 2 IVNSLCPAIYGHELVKAGLLLSlfggKQKYADDKNR-IPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 236 VGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEaDRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPA 315
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGS-QHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 316 YGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHityvhqhsrqppsqfepldMKLMRRYIAMCR-EKQ 394
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH-------------------HQLLRKYISYARqYVN 220
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 395 PMVPESLADYITAAYVEMRREAwASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 464
Cdd:cd17759 221 PVLSKDASEALQEFYLELRKQN-QLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
1-104 |
1.39e-33 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 123.75 E-value: 1.39e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 1 MVVATYTCDQCGAETYQPIQSPTfmpliMCPSQECQtnrSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVL 80
Cdd:pfam17207 30 LKKATFTCRKCGHTVGVKITEPT-----KCPNPECG---NKDPFKLVHEKSKFVDFQKIKIQESPEEVPAGELPRSLDVI 101
|
90 100
....*....|....*....|....
gi 193786225 81 VEGENTRIAQPGDHVSVTGIFLPI 104
Cdd:pfam17207 102 LDDDLVDRVKPGDRVTVTGIYRVV 125
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
382-465 |
1.12e-26 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 103.39 E-value: 1.12e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 382 LMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRL 460
Cdd:pfam17855 2 LLRKYIAYAREKiKPKLSEEAREKLVDAYVELRKESTGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIRL 81
|
....*
gi 193786225 461 MEMSK 465
Cdd:pfam17855 82 LKESL 86
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
200-339 |
7.43e-06 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 45.75 E-value: 7.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 200 NICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSgvGLTAAVLRDSVS---GELTLEGGALVLADQ--GVCCIDEFDKm 274
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVFYVQLTR--DTTEEDLFGRRNidpGGASWVDGPLVRAARegEIAVLDEINR- 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 193786225 275 AEADRTAI-HEVMEQQTISIAKAGILTTLNARC-SILAAANPAYGRYNPrrsleqniqLPAALLSRF 339
Cdd:pfam07728 78 ANPDVLNSlLSLLDERRLLLPDGGELVKAAPDGfRLIATMNPLDRGLNE---------LSPALRSRF 135
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
268-454 |
4.66e-05 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 45.54 E-value: 4.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 268 IDEFDKmaeAD-RT--AIHEVMEQQTISIAKAGIltTLNARCSILAAANP--AYGRYnprrsleqniQLPAALLSRFDL- 341
Cdd:COG0714 100 ADEINR---APpKTqsALLEAMEERQVTIPGGTY--KLPEPFLVIATQNPieQEGTY----------PLPEAQLDRFLLk 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 193786225 342 LWLiqDRPDRDNDLRLaqhityVHQHSRQPPSQFEPLdmkLMRRYIAMCRE--KQPMVPESLADYITAAYVEMRREAWAS 419
Cdd:COG0714 165 LYI--GYPDAEEEREI------LRRHTGRHLAEVEPV---LSPEELLALQElvRQVHVSEAVLDYIVDLVRATREHPDLR 233
|
170 180 190
....*....|....*....|....*....|....*
gi 193786225 420 KDAtytSARTLLAILRLSTALARLRMVDVVEKEDV 454
Cdd:COG0714 234 KGP---SPRASIALLRAARALALLDGRDYVTPDDV 265
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