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Conserved domains on  [gi|158257096|dbj|BAF84521|]
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unnamed protein product [Homo sapiens]

Protein Classification

RCC1 domain-containing protein( domain architecture ID 11474102)

RCC1 (regulator of chromosome condensation) domain-containing protein similar to Arabidopsis UVR8 (UV RESISTANCE LOCUS 8), which plays an important role in mediating the effects of UV-B radiation on pathogen resistance by controlling the expression of the sinapate biosynthetic pathway.

Gene Ontology:  GO:0003682|GO:0005085
PubMed:  9510255|18442486

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 38-360 1.27e-66

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


:

Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 225.24  E-value: 1.27e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096  38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAVSKPTCVKALkpEKVKLAACGRNHTLVSTEGGNVYATGGNNEG 117
Cdd:COG5184    1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGL--SNVVAVAAGGDHTCALKADGTVWCWGNNSYG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096 118 QLGLGDTEERNTFHVISFFTSehkIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIG-KPVSWIS 196
Cdd:COG5184   79 QLGDGTTTDRTTPVKVPGLTG---VVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTTNRLTPVQVDAGlSGVVAIA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQllGNHRTPQLVSEIPEkVIQVACGGEHTVVLTEN-AVYTFGLGQFGQLG 275
Cdd:COG5184  156 AGGYHTCALKSDGTVWCWGANSYGQLGDGTT--TDRPTPVQVGGLSG-VVAVAAGGDHSCALKSDgTVWCWGSNSSGQLG 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096 276 LGTFLFETSePKVIENIRDqtISYISCGENHT-ALITDiGLMYTFGDGRHGKLGLGleNFTNHFIPTLCSNFLRfiVKLV 354
Cdd:COG5184  233 DGTTTDRAT-PVQVAGLTG--VVAIAAGGSHTcALKSD-GTVWCWGDNSYGQLGDG--TTTDRSTPVKVPGLSG--VVAV 304


                 ....*.
gi 158257096 355 ACGGCH 360
Cdd:COG5184  305 AAGSSH 310
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 38-360 1.27e-66

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 225.24  E-value: 1.27e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096  38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAVSKPTCVKALkpEKVKLAACGRNHTLVSTEGGNVYATGGNNEG 117
Cdd:COG5184    1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGL--SNVVAVAAGGDHTCALKADGTVWCWGNNSYG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096 118 QLGLGDTEERNTFHVISFFTSehkIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIG-KPVSWIS 196
Cdd:COG5184   79 QLGDGTTTDRTTPVKVPGLTG---VVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTTNRLTPVQVDAGlSGVVAIA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQllGNHRTPQLVSEIPEkVIQVACGGEHTVVLTEN-AVYTFGLGQFGQLG 275
Cdd:COG5184  156 AGGYHTCALKSDGTVWCWGANSYGQLGDGTT--TDRPTPVQVGGLSG-VVAVAAGGDHSCALKSDgTVWCWGSNSSGQLG 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096 276 LGTFLFETSePKVIENIRDqtISYISCGENHT-ALITDiGLMYTFGDGRHGKLGLGleNFTNHFIPTLCSNFLRfiVKLV 354
Cdd:COG5184  233 DGTTTDRAT-PVQVAGLTG--VVAIAAGGSHTcALKSD-GTVWCWGDNSYGQLGDG--TTTDRSTPVKVPGLSG--VVAV 304


                 ....*.
gi 158257096 355 ACGGCH 360
Cdd:COG5184  305 AAGSSH 310
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
158-205 6.24e-14

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 66.39  E-value: 6.24e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 158257096  158 DGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI--GKPVSWISCGYYHSAFV 205
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGlsGNKVVQVACGGDHTVAL 50
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 38-360 1.27e-66

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 225.24  E-value: 1.27e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096  38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAVSKPTCVKALkpEKVKLAACGRNHTLVSTEGGNVYATGGNNEG 117
Cdd:COG5184    1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPGL--SNVVAVAAGGDHTCALKADGTVWCWGNNSYG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096 118 QLGLGDTEERNTFHVISFFTSehkIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIG-KPVSWIS 196
Cdd:COG5184   79 QLGDGTTTDRTTPVKVPGLTG---VVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGDGTTTNRLTPVQVDAGlSGVVAIA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096 197 CGYYHSAFVTTDGELYVFGEPENGKLGLPNQllGNHRTPQLVSEIPEkVIQVACGGEHTVVLTEN-AVYTFGLGQFGQLG 275
Cdd:COG5184  156 AGGYHTCALKSDGTVWCWGANSYGQLGDGTT--TDRPTPVQVGGLSG-VVAVAAGGDHSCALKSDgTVWCWGSNSSGQLG 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096 276 LGTFLFETSePKVIENIRDqtISYISCGENHT-ALITDiGLMYTFGDGRHGKLGLGleNFTNHFIPTLCSNFLRfiVKLV 354
Cdd:COG5184  233 DGTTTDRAT-PVQVAGLTG--VVAIAAGGSHTcALKSD-GTVWCWGDNSYGQLGDG--TTTDRSTPVKVPGLSG--VVAV 304


                 ....*.
gi 158257096 355 ACGGCH 360
Cdd:COG5184  305 AAGSSH 310
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 38-341 6.70e-65

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 220.23  E-value: 6.70e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096  38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAVSKPTCVKALKPekVKLAACGRNHTLVSTEGGNVYATGGNNEG 117
Cdd:COG5184   51 VAVAAGGDHTCALKADGTVWCWGNNSYGQLGDGTTTDRTTPVKVPGLTG--VVAVAAGYYHSCALKSDGTVWCWGDNSSG 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096 118 QLGLGDTEERNTFHVISffTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISC 197
Cdd:COG5184  129 QLGDGTTTNRLTPVQVD--AGLSGVVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGLSGVVAVAA 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096 198 GYYHSAFVTTDGELYVFGEPENGKLGLPNQllGNHRTPQLVSEiPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQLGL 276
Cdd:COG5184  207 GGDHSCALKSDGTVWCWGSNSSGQLGDGTT--TDRATPVQVAG-LTGVVAIAAGGSHTCALKSDgTVWCWGDNSYGQLGD 283

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 158257096 277 GTFLFETSePKVIENIRDqtISYISCGENHT-ALITDiGLMYTFGDGRHGKLGLGleNFTNHFIPT 341
Cdd:COG5184  284 GTTTDRST-PVKVPGLSG--VVAVAAGSSHTcALLTD-GTVWCWGDNAYGQLGDG--TTTDRSTPV 343
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 37-129 3.05e-19

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 90.04  E-value: 3.05e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096  37 PVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAVSKPTCVKALKPekVKLAACGRNHTLVSTEGGNVYATGGNNE 116
Cdd:COG5184  251 VVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLSG--VVAVAAGSSHTCALLTDGTVWCWGDNAY 328

                         90
                 ....*....|...
gi 158257096 117 GQLGLGDTEERNT 129
Cdd:COG5184  329 GQLGDGTTTDRST 341
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
158-205 6.24e-14

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 66.39  E-value: 6.24e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 158257096  158 DGRLFMWGDNSEGQIGLKNVSNVCVPQQVTI--GKPVSWISCGYYHSAFV 205
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGlsGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
55-101 9.23e-13

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 63.31  E-value: 9.23e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 158257096   55 KLYMFGSNNWGQLGLGSKSAVSKPTCVKALKPEKVKLAACGRNHTLV 101
Cdd:pfam00415   3 RVYTWGRNDYGQLGLGTTENVLVPQKVEGLSGNKVVQVACGGDHTVA 49
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
263-310 2.32e-11

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 59.07  E-value: 2.32e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 158257096  263 VYTFGLGQFGQLGLGTFlFETSEPKVIENIRDQTISYISCGENHTALI 310
Cdd:pfam00415   4 VYTWGRNDYGQLGLGTT-ENVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
208-258 4.30e-11

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 58.68  E-value: 4.30e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 158257096  208 DGELYVFGEPENGKLGLPNQLlgNHRTPQLVSEIPE-KVIQVACGGEHTVVL 258
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTE--NVLVPQKVEGLSGnKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
142-171 1.14e-09

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 53.97  E-value: 1.14e-09
                          10        20        30
                  ....*....|....*....|....*....|
gi 158257096  142 IKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
106-155 2.23e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 47.90  E-value: 2.23e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 158257096  106 GNVYATGGNNEGQLGLGDTEERNTFHVISFFtSEHKIKQLSAGSNTSAAL 155
Cdd:pfam00415   2 GRVYTWGRNDYGQLGLGTTENVLVPQKVEGL-SGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
89-118 6.33e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 46.26  E-value: 6.33e-07
                          10        20        30
                  ....*....|....*....|....*....|
gi 158257096   89 VKLAACGRNHTLVSTEGGNVYATGGNNEGQ 118
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
314-360 2.49e-06

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 45.20  E-value: 2.49e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 158257096  314 GLMYTFGDGRHGKLGLGleNFTNHFIPTLCSNFLRFIVKLVACGGCH 360
Cdd:pfam00415   2 GRVYTWGRNDYGQLGLG--TTENVLVPQKVEGLSGNKVVQVACGGDH 46
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
245-273 3.73e-06

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 43.95  E-value: 3.73e-06
                          10        20        30
                  ....*....|....*....|....*....|
gi 158257096  245 VIQVACGGEHTVVLTEN-AVYTFGLGQFGQ 273
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDgRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
38-66 9.28e-06

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 42.80  E-value: 9.28e-06
                          10        20
                  ....*....|....*....|....*....
gi 158257096   38 VHLSCGDEHSAVVTGNNKLYMFGSNNWGQ 66
Cdd:pfam13540   2 VSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
195-220 1.50e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 42.41  E-value: 1.50e-05
                          10        20
                  ....*....|....*....|....*.
gi 158257096  195 ISCGYYHSAFVTTDGELYVFGEPENG 220
Cdd:pfam13540   4 VAAGDNHTLALTSDGRVYCWGDNSYG 29
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
297-325 4.70e-04

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 38.17  E-value: 4.70e-04
                          10        20
                  ....*....|....*....|....*....
gi 158257096  297 ISYISCGENHTALITDIGLMYTFGDGRHG 325
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYG 29
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
46-215 1.64e-03

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 41.29  E-value: 1.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096  46 HSAVVTGNNKLYMFGsnnwgqlGLGSKSAVSKptcVKALKPEK---VKLAAC---GRNHTLVSTEGGNVYATGGNNEGQl 119
Cdd:COG3055   15 EAAAALLDGKVYVAG-------GLSGGSASNS---FEVYDPATntwSELAPLpgpPRHHAAAVAQDGKLYVFGGFTGAN- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 158257096 120 glGDTEERNTFHVISFFTSE-HKIKQLSAGSNTSAALTEDGRLFMWGdnseGQIGLKNVSNVCVPQQVTigkpVSWISCG 198
Cdd:COG3055   84 --PSSTPLNDVYVYDPATNTwTKLAPMPTPRGGATALLLDGKIYVVG----GWDDGGNVAWVEVYDPAT----GTWTQLA 153

                        170       180
                 ....*....|....*....|...
gi 158257096 199 ------YYHSAFVTTDGELYVFG 215
Cdd:COG3055  154 plptprDHLAAAVLPDGKILVIG 176
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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