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Conserved domains on  [gi|74222436|dbj|BAE38118|]
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unnamed protein product [Mus musculus]

Protein Classification

FKBP_C and TPR domain-containing protein( domain architecture ID 11991378)

FKBP_C and TPR domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
56-145 3.14e-21

FKBP-type peptidyl-prolyl cis-trans isomerase;


:

Pssm-ID: 459735  Cd Length: 94  Bit Score: 86.87  E-value: 3.14e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436    56 GSSRPLKGQVVTVHLQMSLENGTRVQ----EEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPY 131
Cdd:pfam00254   1 GPEKAKKGDRVTVHYTGTLEDGTVFDssydRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGPV 80

                          90
                  ....*....|....
gi 74222436   132 IPPHAALCLEVTLK 145
Cdd:pfam00254  81 IPPNATLVFEVELL 94
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
163-290 5.04e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.03  E-value: 5.04e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 163 ALANRkrecGNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQV 242
Cdd:COG0457  10 AYNNL----GLAYRRLGRYEEAIEDYEKALELDPDDAEA-----------------LYNLGLAYLRLGRYEEALADYEQA 68

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 74222436 243 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 290
Cdd:COG0457  69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNL 116
 
Name Accession Description Interval E-value
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
56-145 3.14e-21

FKBP-type peptidyl-prolyl cis-trans isomerase;


Pssm-ID: 459735  Cd Length: 94  Bit Score: 86.87  E-value: 3.14e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436    56 GSSRPLKGQVVTVHLQMSLENGTRVQ----EEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPY 131
Cdd:pfam00254   1 GPEKAKKGDRVTVHYTGTLEDGTVFDssydRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGPV 80

                          90
                  ....*....|....
gi 74222436   132 IPPHAALCLEVTLK 145
Cdd:pfam00254  81 IPPNATLVFEVELL 94
FkpA COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein ...
 45-144 2.68e-13

FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440311 [Multi-domain]  Cd Length: 104  Bit Score: 65.20  E-value: 2.68e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436  45 LRMKTLVPGpKGSSrPLKGQVVTVHLQMSLENGT----RVQEEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKY 120
Cdd:COG0545   1 LQYKVLKEG-TGAK-PKAGDTVTVHYTGTLLDGTvfdsSYDRGEPATFPLGVGQVIPGWDEGLQGMKVGGKRRLVIPPEL 78

                        90       100
                ....*....|....*....|....
gi 74222436 121 CYGPQGSrSPYIPPHAALCLEVTL 144
Cdd:COG0545  79 AYGERGA-GGVIPPNSTLVFEVEL 101
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
163-290 5.04e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.03  E-value: 5.04e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 163 ALANRkrecGNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQV 242
Cdd:COG0457  10 AYNNL----GLAYRRLGRYEEAIEDYEKALELDPDDAEA-----------------LYNLGLAYLRLGRYEEALADYEQA 68

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 74222436 243 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 290
Cdd:COG0457  69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNL 116
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 221-283 9.05e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 46.85  E-value: 9.05e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 74222436 221 NLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 283
Cdd:cd24142   5 EKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG 67
TPR_19 pfam14559
Tetratricopeptide repeat;
232-293 1.23e-05

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 42.57  E-value: 1.23e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 74222436   232 YRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKL 293
Cdd:pfam14559   4 YAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 219-296 5.35e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 5.35e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 74222436   219 LNNLAASQLKLDHYRAaLRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKK 296
Cdd:TIGR02917 807 LNNLAWLYLELKDPRA-LEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLA 883
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 250-283 1.02e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.97  E-value: 1.02e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 74222436    250 IKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 283
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
FKBP_C pfam00254
FKBP-type peptidyl-prolyl cis-trans isomerase;
56-145 3.14e-21

FKBP-type peptidyl-prolyl cis-trans isomerase;


Pssm-ID: 459735  Cd Length: 94  Bit Score: 86.87  E-value: 3.14e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436    56 GSSRPLKGQVVTVHLQMSLENGTRVQ----EEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPY 131
Cdd:pfam00254   1 GPEKAKKGDRVTVHYTGTLEDGTVFDssydRGKPFEFTLGSGQVIPGWDEGLVGMKVGEKRKLTIPPELAYGEEGLAGPV 80

                          90
                  ....*....|....
gi 74222436   132 IPPHAALCLEVTLK 145
Cdd:pfam00254  81 IPPNATLVFEVELL 94
FkpA COG0545
FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein ...
 45-144 2.68e-13

FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440311 [Multi-domain]  Cd Length: 104  Bit Score: 65.20  E-value: 2.68e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436  45 LRMKTLVPGpKGSSrPLKGQVVTVHLQMSLENGT----RVQEEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKY 120
Cdd:COG0545   1 LQYKVLKEG-TGAK-PKAGDTVTVHYTGTLLDGTvfdsSYDRGEPATFPLGVGQVIPGWDEGLQGMKVGGKRRLVIPPEL 78

                        90       100
                ....*....|....*....|....
gi 74222436 121 CYGPQGSrSPYIPPHAALCLEVTL 144
Cdd:COG0545  79 AYGERGA-GGVIPPNSTLVFEVEL 101
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
163-290 5.04e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.03  E-value: 5.04e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 163 ALANRkrecGNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQV 242
Cdd:COG0457  10 AYNNL----GLAYRRLGRYEEAIEDYEKALELDPDDAEA-----------------LYNLGLAYLRLGRYEEALADYEQA 68

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 74222436 243 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 290
Cdd:COG0457  69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNL 116
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 163-290 1.90e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 65.40  E-value: 1.90e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 163 ALANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQV 242
Cdd:COG3914  76 LLAALLELAALLLQALGRYEEALALYRRALALNPDNAEA-----------------LFNLGNLLLALGRLEEALAALRRA 138

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 74222436 243 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 290
Cdd:COG3914 139 LALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNL 186
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
163-290 2.22e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.10  E-value: 2.22e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 163 ALANRkrecGNAHYQRADFVLAANSYDLAIKAITSNtkvdmtceeeeellqlkVKCLNNLAASQLKLDHYRAALRSCSQV 242
Cdd:COG0457  44 ALYNL----GLAYLRLGRYEEALADYEQALELDPDD-----------------AEALNNLGLALQALGRYEEALEDYDKA 102

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 74222436 243 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 290
Cdd:COG0457 103 LELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNL 150
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 172-290 6.09e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.47  E-value: 6.09e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 172 GNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIK 251
Cdd:COG3914 119 GNLLLALGRLEEALAALRRALALNPDFAEA-----------------YLNLGEALRRLGRLEEAIAALRRALELDPDNAE 181

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 74222436 252 ALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 290
Cdd:COG3914 182 ALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 219-312 1.40e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 58.66  E-value: 1.40e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 219 LNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSkLVKKRA 298
Cdd:COG4783   7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLG-LALLKA 85

                        90
                ....*....|....
gi 74222436 299 AQRSTETALYRKML 312
Cdd:COG4783  86 GDYDEALALLEKAL 99
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 172-283 1.21e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.78  E-value: 1.21e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 172 GNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIK 251
Cdd:COG4235  24 GRAYLRLGRYDEALAAYEKALRLDPDNADA-----------------LLDLAEALLAAGDTEEAEELLERALALDPDNPE 86

                        90       100       110
                ....*....|....*....|....*....|..
gi 74222436 252 ALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 283
Cdd:COG4235  87 ALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
122-283 5.00e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 56.08  E-value: 5.00e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 122 YGPQGSRSPYIPPHAALCLEVTLktAEDGPDLEMLSGQERVALANRkrecGNAHYQRADFVLAANSYDLAIKAITSNTKV 201
Cdd:COG4785  36 ALAIALADLALALAAAALAAAAL--AAERIDRALALPDLAQLYYER----GVAYDSLGDYDLAIADFDQALELDPDLAEA 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 202 dmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEP 281
Cdd:COG4785 110 -----------------YNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDP 172


                ..
gi 74222436 282 SN 283
Cdd:COG4785 173 ND 174
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 172-312 6.04e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.04  E-value: 6.04e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 172 GNAHYQRADFVLAANSYDLAIKAITSNTKVdmtceeeeellqlkvkcLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIK 251
Cdd:COG4783  11 AQALLLAGDYDEAEALLEKALELDPDNPEA-----------------FALLGEILLQLGDLDEAIVLLHEALELDPDEPE 73

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74222436 252 ALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLvKKRAAQRSTETALYRKML 312
Cdd:COG4783  74 ARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARA-YRALGRPDEAIAALEKAL 133
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 174-315 6.86e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.20  E-value: 6.86e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 174 AHYQRADFVLAANSYDLAIKAITSNTKVDMTCEEEEELLQLKVKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKAL 253
Cdd:COG5010  12 LYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELY 91

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 74222436 254 FRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKRAAQRSTETALYRKMLGNP 315
Cdd:COG5010  92 YNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 221-290 8.92e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.47  E-value: 8.92e-09
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 221 NLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 290
Cdd:COG4235  22 LLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLL 91
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
226-293 1.72e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 51.32  E-value: 1.72e-08
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 74222436 226 QLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPiLRAALKLEPSNKTIHAELSKL 293
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAEL 68
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 218-316 2.86e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.35  E-value: 2.86e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 218 CLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKR 297
Cdd:COG2956 146 AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225

                        90
                ....*....|....*....
gi 74222436 298 AAQRSTETALYRKMLGNPS 316
Cdd:COG2956 226 GDPEEALELLRKALELDPS 244
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 222-320 7.20e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.23  E-value: 7.20e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 222 LAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVkkRAAQR 301
Cdd:COG3914  84 AALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL--RRLGR 161

                        90       100
                ....*....|....*....|.
gi 74222436 302 STE-TALYRKMLG-NPSRLPA 320
Cdd:COG3914 162 LEEaIAALRRALElDPDNAEA 182
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 164-312 1.60e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 52.04  E-value: 1.60e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 164 LANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVDMTCeeeeellqlkVKCLNNLAASQLKLDHYRAALRSCSQVL 243
Cdd:COG2956 136 LLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDC----------ARALLLLAELYLEQGDYEEAIAALERAL 205

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74222436 244 EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNktihAELSKLVKKRAAQRSTETA--LYRKML 312
Cdd:COG2956 206 EQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD----DLLLALADLLERKEGLEAAlaLLERQL 272
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
163-308 2.34e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.16  E-value: 2.34e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 163 ALANRkrecGNAHYQRADFVLAANSYDLAIKAITSNtkvdmtceeeeellqlkVKCLNNLAASQLKLDHYRAALRSCSQV 242
Cdd:COG0457  78 ALNNL----GLALQALGRYEEALEDYDKALELDPDD-----------------AEALYNLGLALLELGRYDEAIEAYERA 136

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 74222436 243 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKRAAQRSTETALY 308
Cdd:COG0457 137 LELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLA 202
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 176-314 2.79e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 51.27  E-value: 2.79e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 176 YQRADFVLAANSYDLAIKAITSNTKVDmtceeeeellQLKVKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFR 255
Cdd:COG2956  12 YFKGLNYLLNGQPDKAIDLLEEALELD----------PETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLE 81

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74222436 256 KGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKL------------VKKRAAQRSTETALYRKMLGN 314
Cdd:COG2956  82 LAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIyeqegdwekaieVLERLLKLGPENAHAYCELAE 152
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 219-293 3.91e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.88  E-value: 3.91e-07
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 74222436 219 LNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKL 293
Cdd:COG2956  79 LLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAEL 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
219-282 4.28e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 47.47  E-value: 4.28e-07
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 74222436 219 LNNLAASQLKLDHYRAALRsCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPS 282
Cdd:COG3063  29 LNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 219-283 1.53e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.11  E-value: 1.53e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 74222436 219 LNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 283
Cdd:COG4783  75 RLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 234-290 2.98e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.15  E-value: 2.98e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 74222436 234 AALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 290
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL 57
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 219-300 4.35e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.98  E-value: 4.35e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 219 LNNLAASQLKLDHYRAALRSCSQVLEHQPDNIK---ALFRKGKVLAQQGEYSEAIPILRAALKLEPSnktihAELSKLVK 295
Cdd:COG1729  33 LYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDKARATLEELIKKYPD-----SEAAKEAR 107


                ....*
gi 74222436 296 KRAAQ 300
Cdd:COG1729 108 ARLAR 112
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 164-320 7.06e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.03  E-value: 7.06e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 164 LANRKRECGNAHYQRADFVLAANSYDLAIKAITSNTKVDmtceeeeellQLKVKCLNNLAASQLKLDHYRAALRSCSQVL 243
Cdd:COG2956  68 LLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELD----------PDDAEALRLLAEIYEQEGDWEKAIEVLERLL 137

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 244 EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLvkkRAAQRSTETAL--YRKMLG-NPSRLPA 320
Cdd:COG2956 138 KLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAEL---YLEQGDYEEAIaaLERALEqDPDYLPA 214
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 221-283 9.05e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 46.85  E-value: 9.05e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 74222436 221 NLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 283
Cdd:cd24142   5 EKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG 67
TPR_19 pfam14559
Tetratricopeptide repeat;
232-293 1.23e-05

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 42.57  E-value: 1.23e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 74222436   232 YRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKL 293
Cdd:pfam14559   4 YAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 219-296 5.35e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 5.35e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 74222436   219 LNNLAASQLKLDHYRAaLRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKK 296
Cdd:TIGR02917 807 LNNLAWLYLELKDPRA-LEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLA 883
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 250-283 1.02e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 38.97  E-value: 1.02e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 74222436    250 IKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 283
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
250-283 1.04e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.94  E-value: 1.04e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 74222436   250 IKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 283
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
243-290 1.10e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.07  E-value: 1.10e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*...
gi 74222436 243 LEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 290
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNL 48
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 143-320 1.70e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 43.43  E-value: 1.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436   143 TLKTAEDGPDLEM-----LSGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAitsntKVDMTCeeeeellqlkvk 217
Cdd:TIGR00990 100 PVEPADELPEIDEssvanLSEEERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAIEC-----KPDPVY------------ 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436   218 cLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRA-ALKLEPSNKTIHAELSKLVKK 296
Cdd:TIGR00990 163 -YSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANAYDGLGKYADALLDLTAsCIIDGFRNEQSAQAVERLLKK 241

                         170       180
                  ....*....|....*....|....
gi 74222436   297 RAaqrstETALYRKMLGNPSRLPA 320
Cdd:TIGR00990 242 FA-----ESKAKEILETKPENLPS 260
TPR_11 pfam13414
TPR repeat;
257-296 2.59e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 38.22  E-value: 2.59e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 74222436   257 GKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKK 296
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYK 40
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 216-321 3.20e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 3.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436   216 VKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKL---EPSNKTIHAELSK 292
Cdd:TIGR02917 193 VDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKapnSPLAHYLKALVDF 272

                          90       100
                  ....*....|....*....|....*....
gi 74222436   293 LVKKRAAQRSTETALYRKmlgNPSRLPAK 321
Cdd:TIGR02917 273 QKKNYEDARETLQDALKS---APEYLPAL 298
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 251-281 5.41e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.12  E-value: 5.41e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 74222436   251 KALFRKGKVLAQQGEYSEAIPILRAALKLEP 281
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDP 32
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 221-283 9.05e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 37.32  E-value: 9.05e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 74222436   221 NLAASQLKLDHYRAALRSCSQVLEHQ---PDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 283
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 172-307 1.04e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 1.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436   172 GNAHYQRADFVLAANSYDLAIKAITSNtkvdmtceeeeellQLKVKclnnLAASQLKLDHYRAALRSCSQVLEHQPDNIK 251
Cdd:TIGR02917 710 GDLYLRQKDYPAAIQAYRKALKRAPSS--------------QNAIK----LHRALLASGNTAEAVKTLEAWLKTHPNDAV 771

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 74222436   252 ALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKRAAQRSTETAL 307
Cdd:TIGR02917 772 LRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDPRALEYAE 827
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 225-307 1.53e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.66  E-value: 1.53e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74222436 225 SQLKLDHYRAALRSCSQVLEHQPDNI---KALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKRAAQR 301
Cdd:COG1729   2 ALLKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELG 81


                ....*.
gi 74222436 302 STETAL 307
Cdd:COG1729  82 DYDKAR 87
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 216-249 2.28e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 2.28e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 74222436    216 VKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDN 249
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_8 pfam13181
Tetratricopeptide repeat;
250-282 3.43e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 34.68  E-value: 3.43e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 74222436   250 IKALFRKGKVLAQQGEYSEAIPILRAALKLEPS 282
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 222-283 3.57e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 3.57e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 74222436   222 LAASQLKLDHYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSN 283
Cdd:TIGR02917 607 LGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDN 668
TPR_1 pfam00515
Tetratricopeptide repeat;
216-249 5.41e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.32  E-value: 5.41e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 74222436   216 VKCLNNLAASQLKLDHYRAALRSCSQVLEHQPDN 249
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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