|
Name |
Accession |
Description |
Interval |
E-value |
| EP400_N |
pfam15790 |
E1A-binding protein p400, N-terminal; EP400_N is a family of eukaryote proteins. the exact ... |
1-451 |
3.49e-178 |
|
E1A-binding protein p400, N-terminal; EP400_N is a family of eukaryote proteins. the exact function of this domain is not known. This family is largely low-complexity residues.
Pssm-ID: 434938 [Multi-domain] Cd Length: 489 Bit Score: 514.93 E-value: 3.49e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 1 MHHGSGPQNVQHQLQRSRSFTGSEE----EQPAHPNLPPSPAAPFAPSASPSAPQSPGYQIqqLMSRSPVAGQNVNITLQ 76
Cdd:pfam15790 1 MHHGSGSQNVQRQLQRSKSVSGSEEqqqeQQPATVNHPQSPVTTFAPAASPSAPQSPNYQI--IMSRSPVTGQNVNITLQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 77 NVGPVVGGNQQITLAPLPLPNPTSPGFQFGAQQRRFEHGSPSYIQVTSPMSQQVQTQSPTQPSPGPGQTLQnvRAGAPGP 156
Cdd:pfam15790 79 NVGQMVAGNQQITLTPLPLQSPASPGFQHSAPQWRFEHGSPSYIQVTSPLPQQVQPQSPTQHSPVPLQGVQ--RPGAPGT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 157 GLGICSNSPTGgFVDASVLVRQISL-SPSSGGHFVFQEAPGLTQMAQG-AQVQLQHSGAPITVRERRLSQPHAQSGGTIH 234
Cdd:pfam15790 157 GLGVCGQSPTR-FVDASMLVRQISLgSPSGGGHFVYQDGTGLAQIAPGaGQVQLASPGTPGSVRERRLSQPHSQTGGTIH 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 235 HLGPQSPAAAGgTGLQPLASPNHITTASLPPQISSIIQGQliqqqqqvlqgqpMNRSLGFERTPGVLLPGVGGPSA-FGM 313
Cdd:pfam15790 236 HLGPQSPAAAG-AGLQTLGSPGHITTSNLPPQISSIIQGQ-------------LARPLGFEKTAQVVVAGAGGPAAsFGI 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 314 TSPPPPTSPSRTTMPPGLSSVPLTSMGSSG-MKKVPKKLEEIPPASQEMAQMRKQCLDYHYKEMEALKEVFKEYLIELFF 392
Cdd:pfam15790 302 PSSIPPTSPSRTSPPPGLSSNPLTSTGMSGsVKKVPKKLEEIAPATPEIAQLRKQCLDHHTKKMESLKEVFKEYLIELFF 381
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 74210751 393 LQHLQGNMMDFLAFKKKHYAPLQAYLRQNDLDIEEEEEEEEeeegKSEVINDEHQSLTG 451
Cdd:pfam15790 382 LQHLQGNMMDFLAFKKKHCVPLYTYLRQNDLDLEEEEEEEE----QSEVINDEVKVVTG 436
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
508-645 |
9.96e-06 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 48.88 E-value: 9.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 508 PTVQGGMPPTPQATQltGQKQSQQQYDPSTGPPVQNAASLHTPPPQLPARLPPasvpatalPSTLQFSQQSQMVEASTQL 587
Cdd:pfam09770 212 QQPAPAPAQPPAAPP--AQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHP--------VTILQRPQSPQPDPAQPSI 281
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 588 QIPVKTQQLNAPIPAPLPSQ-LPAPSSQPA-QPALHVPMPGKAQMQTSQLSSQTQVLCGH 645
Cdd:pfam09770 282 QPQAQQFHQQPPPVPVQPTQiLQNPNRLSAaRVGYPQNPQPGVQPAPAHQAHRQQGSFGR 341
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
513-646 |
1.46e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.90 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 513 GMPPTPQATQLTGQKQSQQQYDPSTGPPVQNAASLHTPPPQLPARLPPASVPATALPSTLQFSQQSQMVEASTQLQIPVK 592
Cdd:PRK07764 384 RLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPS 463
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 74210751 593 TQQLNAPIPAPLPSQLPAPSSQPAQ-PALHVPMPgkAQMQTSQLSSQTQVLCGHW 646
Cdd:PRK07764 464 AQPAPAPAAAPEPTAAPAPAPPAAPaPAAAPAAP--AAPAAPAGADDAATLRERW 516
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| EP400_N |
pfam15790 |
E1A-binding protein p400, N-terminal; EP400_N is a family of eukaryote proteins. the exact ... |
1-451 |
3.49e-178 |
|
E1A-binding protein p400, N-terminal; EP400_N is a family of eukaryote proteins. the exact function of this domain is not known. This family is largely low-complexity residues.
Pssm-ID: 434938 [Multi-domain] Cd Length: 489 Bit Score: 514.93 E-value: 3.49e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 1 MHHGSGPQNVQHQLQRSRSFTGSEE----EQPAHPNLPPSPAAPFAPSASPSAPQSPGYQIqqLMSRSPVAGQNVNITLQ 76
Cdd:pfam15790 1 MHHGSGSQNVQRQLQRSKSVSGSEEqqqeQQPATVNHPQSPVTTFAPAASPSAPQSPNYQI--IMSRSPVTGQNVNITLQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 77 NVGPVVGGNQQITLAPLPLPNPTSPGFQFGAQQRRFEHGSPSYIQVTSPMSQQVQTQSPTQPSPGPGQTLQnvRAGAPGP 156
Cdd:pfam15790 79 NVGQMVAGNQQITLTPLPLQSPASPGFQHSAPQWRFEHGSPSYIQVTSPLPQQVQPQSPTQHSPVPLQGVQ--RPGAPGT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 157 GLGICSNSPTGgFVDASVLVRQISL-SPSSGGHFVFQEAPGLTQMAQG-AQVQLQHSGAPITVRERRLSQPHAQSGGTIH 234
Cdd:pfam15790 157 GLGVCGQSPTR-FVDASMLVRQISLgSPSGGGHFVYQDGTGLAQIAPGaGQVQLASPGTPGSVRERRLSQPHSQTGGTIH 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 235 HLGPQSPAAAGgTGLQPLASPNHITTASLPPQISSIIQGQliqqqqqvlqgqpMNRSLGFERTPGVLLPGVGGPSA-FGM 313
Cdd:pfam15790 236 HLGPQSPAAAG-AGLQTLGSPGHITTSNLPPQISSIIQGQ-------------LARPLGFEKTAQVVVAGAGGPAAsFGI 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 314 TSPPPPTSPSRTTMPPGLSSVPLTSMGSSG-MKKVPKKLEEIPPASQEMAQMRKQCLDYHYKEMEALKEVFKEYLIELFF 392
Cdd:pfam15790 302 PSSIPPTSPSRTSPPPGLSSNPLTSTGMSGsVKKVPKKLEEIAPATPEIAQLRKQCLDHHTKKMESLKEVFKEYLIELFF 381
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 74210751 393 LQHLQGNMMDFLAFKKKHYAPLQAYLRQNDLDIEEEEEEEEeeegKSEVINDEHQSLTG 451
Cdd:pfam15790 382 LQHLQGNMMDFLAFKKKHCVPLYTYLRQNDLDLEEEEEEEE----QSEVINDEVKVVTG 436
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
508-645 |
9.96e-06 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 48.88 E-value: 9.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 508 PTVQGGMPPTPQATQltGQKQSQQQYDPSTGPPVQNAASLHTPPPQLPARLPPasvpatalPSTLQFSQQSQMVEASTQL 587
Cdd:pfam09770 212 QQPAPAPAQPPAAPP--AQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHP--------VTILQRPQSPQPDPAQPSI 281
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 588 QIPVKTQQLNAPIPAPLPSQ-LPAPSSQPA-QPALHVPMPGKAQMQTSQLSSQTQVLCGH 645
Cdd:pfam09770 282 QPQAQQFHQQPPPVPVQPTQiLQNPNRLSAaRVGYPQNPQPGVQPAPAHQAHRQQGSFGR 341
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
501-642 |
1.96e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 44.64 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 501 VPLQQLMPTVQGGMPPTPQATQLTGQKQSQQQYDPSTGPP------VQNAASLHTPPPQLPARLPPASVPATALPSTLQF 574
Cdd:pfam09770 153 IPDLQVDASLWGVAPKKAAAPAPAPQPAAQPASLPAPSRKmmsleeVEAAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQ 232
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74210751 575 SQQSQMVEASTQLQIPVKTQQLNAPIPAPLPSQL---PAPSSQPAQPALHVPMPGKAQMQTSQLSSQTQVL 642
Cdd:pfam09770 233 QQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILqrpQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQIL 303
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
513-646 |
1.46e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.90 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 513 GMPPTPQATQLTGQKQSQQQYDPSTGPPVQNAASLHTPPPQLPARLPPASVPATALPSTLQFSQQSQMVEASTQLQIPVK 592
Cdd:PRK07764 384 RLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPS 463
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 74210751 593 TQQLNAPIPAPLPSQLPAPSSQPAQ-PALHVPMPgkAQMQTSQLSSQTQVLCGHW 646
Cdd:PRK07764 464 AQPAPAPAAAPEPTAAPAPAPPAAPaPAAAPAAP--AAPAAPAGADDAATLRERW 516
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
474-634 |
1.53e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 41.99 E-value: 1.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 474 PTEQSKRPRLEVGHPGVVFQH-PGVNAGVPLQQLMPTvqgGMPPTPQATQLTGQKQS--QQQYDPSTGPPVQNAASLHTP 550
Cdd:PRK10263 342 QTPPVASVDVPPAQPTVAWQPvPGPQTGEPVIAPAPE---GYPQQSQYAQPAVQYNEplQQPVQPQQPYYAPAAEQPAQQ 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 551 PPQLPARLPPASVPATALPSTLQFSQQSQMVEASTQLQIPVKTQQLNAPIPAPLPSQLPAPSSQPAQPALHV-PMPGKAQ 629
Cdd:PRK10263 419 PYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVePEPVVEE 498
|
....*
gi 74210751 630 MQTSQ 634
Cdd:PRK10263 499 TKPAR 503
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
537-638 |
1.85e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 41.24 E-value: 1.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 537 TGPPVQNAASLHTPPPQLPARLPPASVPATALPSTLQFSQQSQMVEASTQLQiPVKTQQLNA----PIPAPLPSQLPAPS 612
Cdd:PRK14951 371 EAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAP-PAPVAAPAAaapaAAPAAAPAAVALAP 449
|
90 100
....*....|....*....|....*..
gi 74210751 613 SQPAQPALH-VPMPGKAQMQTSQLSSQ 638
Cdd:PRK14951 450 APPAQAAPEtVAIPVRVAPEPAVASAA 476
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
493-642 |
2.03e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 41.29 E-value: 2.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 493 QHPGVNAGVPLQQLMPTVQGGMPPTPQATQLTGQKQSQqqydpstgPPVQNAASLHTPPPQLPARLPPASVPATALPSTL 572
Cdd:pfam03154 290 QHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHT--------PPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTT 361
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 573 QFsqqSQMVEASTQLQIPvktqQLNAPIPAPLPSQLPAPSSQPAQPALHVPMPGKAQMQTSQLSSQTQVL 642
Cdd:pfam03154 362 PI---PQLPNPQSHKHPP----HLSGPSPFQMNSNLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQQL 424
|
|
| PRK10927 |
PRK10927 |
cell division protein FtsN; |
462-566 |
2.59e-03 |
|
cell division protein FtsN;
Pssm-ID: 236797 [Multi-domain] Cd Length: 319 Bit Score: 40.43 E-value: 2.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 462 EADPFKRQQVMppTEQSKRPRLEVGHPgvvFQHPGVNAGVPLQQLMPTVQGgmPPTPQATQLTGQKQSQQQYDPSTGPPV 541
Cdd:PRK10927 143 EQTPEQRQQTL--QRQRQAQQLAEQQR---LAQQSRTTEQSWQQQTRTSQA--APVQAQPRQSKPASTQQPYQDLLQTPA 215
|
90 100
....*....|....*....|....*
gi 74210751 542 QNAASLHTPPPQLPARLPPASVPAT 566
Cdd:PRK10927 216 HTTAQSKPQQAAPVTRAADAPKPTA 240
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
536-634 |
3.87e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 40.47 E-value: 3.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 536 STGPPVQNAASLHTPPPQLPARLPPASVPATAlPSTLQFSQQSQMVEASTQLQIPVKTQqlnaPIPAPlPSQLPAPSSQP 615
Cdd:PRK14951 410 AASAPAAPPAAAPPAPVAAPAAAAPAAAPAAA-PAAVALAPAPPAQAAPETVAIPVRVA----PEPAV-ASAAPAPAAAP 483
|
90
....*....|....*....
gi 74210751 616 AQPALHVPMPGKAQMQTSQ 634
Cdd:PRK14951 484 AAARLTPTEEGDVWHATVQ 502
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
506-629 |
6.77e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 39.47 E-value: 6.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 506 LMPTVQGG--MPPTPQATQLTGQKQSQQQYDPSTGPPVQNAASLHTPPPQLPARLPPASVPATALPS--TLQFSQQSQMV 581
Cdd:PRK12323 363 FRPGQSGGgaGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPApeALAAARQASAR 442
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 74210751 582 EASTQLQIPvktqqlNAPIPAPLPSQLPAPSSQPAQPALHVPMPGKAQ 629
Cdd:PRK12323 443 GPGGAPAPA------PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAA 484
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
507-629 |
7.73e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 39.46 E-value: 7.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74210751 507 MPTVQGGMPPTPQATQLTGQKQSQQQYDPSTGPPVQNAASLHTPPPQLPARLPPASVPATALPSTLQFSQQSQMVEASTQ 586
Cdd:PRK07994 363 APLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSE 442
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 74210751 587 LQIPVKTQQLNAPIpAPLPSQLPAPSSQPAQPALHVPMPGKAQ 629
Cdd:PRK07994 443 PAAASRARPVNSAL-ERLASVRPAPSALEKAPAKKEAYRWKAT 484
|
|
|